WO2023169069A1 - Novel nicotine-free chinese herbal medicine cigarette and preparation method therefor - Google Patents

Novel nicotine-free chinese herbal medicine cigarette and preparation method therefor Download PDF

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Publication number
WO2023169069A1
WO2023169069A1 PCT/CN2023/070044 CN2023070044W WO2023169069A1 WO 2023169069 A1 WO2023169069 A1 WO 2023169069A1 CN 2023070044 W CN2023070044 W CN 2023070044W WO 2023169069 A1 WO2023169069 A1 WO 2023169069A1
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chinese herbal
nicotine
free
take
preparation
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PCT/CN2023/070044
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French (fr)
Chinese (zh)
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李欣
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湖南百草香灸生物科技有限公司
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Publication of WO2023169069A1 publication Critical patent/WO2023169069A1/en

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    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/20Biochemical treatment
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24DCIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D1/00Cigars; Cigarettes
    • A24D1/18Selection of materials, other than tobacco, suitable for smoking
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Definitions

  • the invention belongs to the field of new cigarettes, and specifically relates to a new type of Chinese herbal nicotine-free cigarette and its preparation method.
  • Smoking is very harmful. Tobacco contains a variety of toxic substances. The smoke produced when tobacco is burned contains about 1,000 harmful components. Among them, tar, carbon monoxide and nicotine are deadly substances. Tar will reduce the function of cilia in purifying the air; carbon monoxide will combine with hemoglobin and drive away oxygen, causing the body to become hypoxic; nicotine is the most harmful and addictive.
  • Long-term smoking is very harmful, mainly in the following aspects: (1) Causes respiratory diseases. Long-term smoking can easily cause chronic inflammation of the respiratory mucosa. In severe cases, congestion, edema, inflammatory secretions may occur, and may even cause structural changes in the respiratory mucosa, leading to bronchitis, chronic obstructive pulmonary disease, and chronic pulmonary disease. Heart disease, as well as bronchiectasis, can even cause some malignant tumors, such as lung cancer. (2) Cause cardiovascular and cerebrovascular diseases. Long-term smokers are prone to coronary atherosclerotic heart disease, hypertension, and cerebrovascular disease. (3) Cause digestive system diseases.
  • the technical problem to be solved by the present invention is that existing cigarettes produce a variety of harmful substances when smoking and endanger human health.
  • the technical solution of the present invention to solve the above technical problems is to provide a new type of Chinese herbal nicotine-free cigarette.
  • the composition of the above-mentioned cigarettes includes: 20-100g of angelica, 20-100g of wolfberry, 20-100g of ganoderma, 20-100g of fairy spleen, 20-100g of Chinese yam, 20-100g of cordyceps, 20-100g of curculigo, 20-100g of honeycomb, and eucommia ulmoides.
  • the composition of the above-mentioned new Chinese herbal nicotine-free cigarettes includes: 20g Angelica sinensis, 20g Lycium barbarum, 20g Ganoderma lucidum, 20g Xianlingpi, 20g Chinese yam, 20g Cordyceps sinensis, 20g curculigo, 20g honeycomb, 30g Eucommia ulmoides, 20g Dipsacus root.
  • the invention also provides a preparation method for the above-mentioned novel Chinese herbal nicotine-free cigarette, which includes the following steps:
  • step d Stir and mix the particles obtained in step b and the shredded tobacco obtained in step c, then add the Chinese herbal medicine rock sugar wine obtained in step a, and take it out after 7-10 days to obtain a mixture of shredded tobacco and Chinese herbal medicine;
  • step e Take pears, grapes, apples, and mangoes to make juice. Pour the compound fungal polysaccharide in step e into the juice. The volume ratio of the compound fungal polysaccharide to the juice is 1:3-5. Store it in a can and seal for 1-2 Months, get fungal polysaccharide probiotic enzyme;
  • step g Mix the Chinese herbal medicine mixture of shredded tobacco obtained in step d and the fungal polysaccharide probiotic enzyme obtained in step f, seal and store it for 1-2 months, take it out and dry it in the sun, and take the particles of more than 10 mesh and within 2 mm to obtain a mixture of Chinese patent shredded tobacco. Put it into an empty cigarette tube to get a new type of Chinese herbal nicotine-free cigarette.
  • step a the dosage of the grain wine is 2-5 times the total amount of medicinal materials in step a.
  • step c the added amount of the microorganism Pseudomonas putida is 10-20% of the amount of shredded tobacco.
  • step c the concentration of the microorganism Pseudomonas putida is 5-20%.
  • the invention provides a new type of Chinese herbal medicine nicotine-free cigarette and a preparation method thereof.
  • the nicotine-free tobacco leaves are used as the medicine, and the beneficial ingredients produced by the fermentation of Chinese herbal medicines that are beneficial to various human skills are inhaled into the lungs through smoking, because The lungs connect hundreds of meridians, the lungs govern qi, the heart governs blood, qi pushes the blood away, and the blood moves with the qi.
  • the aerosol carries the active ingredients of various Chinese herbal medicines and penetrates into the internal organs, various meridians and cells of the body, which will cause the body to get sick.
  • the new Chinese herbal nicotine-free cigarette of the present invention has the appearance and smoking method of a cigarette, and has tobacco leaves. It feels like smoking when smoked. However, because it does not contain nicotine, it will not cause cigarette addiction, but will reduce the cigarette craving. At the same time, it will be smoked through smoking. Chinese herbal medicine is brought into the alveolar cells to improve the morphology of the alveolar cells and achieve the effect of regulating the body.
  • the present invention selects a variety of lung-moistening Chinese herbal medicines to jointly prepare a Chinese herbal nicotine-free cigarette.
  • the nicotine-free tobacco leaves are used as the drug guide, and are inhaled into the lungs through smoking, because the lungs connect hundreds of meridians, the lungs govern qi, the heart governs blood, and qi. Pushing the blood away, the blood follows the flow of Qi.
  • the aerosol carries the active ingredients of various Chinese herbal medicines and penetrates into the human body's internal organs, various meridians and cells, expelling the moisture, cold air and toxins that cause the human body to become sick, and opening up the body's stasis and blockage. This place allows all parts of the human body to function normally and achieves the effect of regulating various diseases.
  • Angelica sinensis nourishes blood and activates blood circulation, regulates menstruation and relieves pain, moistens the intestines and relieves constipation; it is mainly used to treat blood deficiency and chlorosis, irregular menstruation, amenorrhea and dysmenorrhea, blood deficiency, blood stagnation, cold blood and various pains, bruises and rheumatic paralysis. Pain, ulcers, ulcers, intestinal dryness, constipation, etc.
  • Lycium barbarum nourishes the liver and kidneys, replenishes essence and improves eyesight, and is mainly used to treat liver and kidney yin deficiency and premature aging.
  • Ganoderma lucidum nourishes qi and calms the mind, relieves cough and asthma, and is mainly used to treat restlessness, cough and asthma with excessive phlegm, and fatigue syndrome.
  • Xianling spleen has the effects of nourishing the kidneys and strengthening the heart, strengthening yang and relieving paralysis. It is used for impotence and spermatorrhea, weak muscles and bones, chest tightness and dizziness, shortness of breath and fatigue, rheumatic arthralgia, etc.
  • Yam has the effects of replenishing qi and nourishing yin, nourishing the spleen, lungs and kidneys, strengthening essence and stopping vaginal discharge. Indications: Spleen deficiency, less food, fatigue, loose stools and diarrhea, lung deficiency, asthma and cough, kidney deficiency, spermatorrhea, vaginal discharge, frequent urination, internal heat and thirst, etc.
  • Cordyceps sinensis has the effects of nourishing the kidneys and lungs, stopping bleeding and reducing phlegm. It is mainly used to treat impotence and spermatorrhea, soreness of waist and knees, chronic cough, shortness of breath, and labor cough with bloody phlegm.
  • Curculigo has the effects of warming the kidneys and strengthening yang, dispelling cold and dehumidifying. It is mainly used to treat impotence, cold essence, enuresis and frequent urination, cold-damp arthralgia, weakness of muscles and bones, abdominal pain, cold diarrhea, etc.
  • the hive has the effects of attacking poisons and killing insects, dispelling wind and relieving pain. Mainly used to treat carbuncle, boils, scrofula, scabies, rash and itching, rheumatic arthralgia, toothache, sore throat, etc.
  • Eucommia ulmoides has the effects of nourishing the liver and kidneys, strengthening muscles and bones, and preventing miscarriage. It is mainly used to treat low back pain due to kidney deficiency and various low back pains, restless fetal movements, and habitual abortion.
  • Achyranthes bidentata has the effects of promoting blood circulation and promoting menstruation, nourishing the liver and kidneys, strengthening the muscles and bones, diluting water and relieving stranguria, and inducing the downward movement of fire (blood).
  • Dipsacus has the effects of nourishing the liver and kidneys, strengthening muscles and bones, and promoting blood vessels. It is mainly used to treat liver and kidney deficiency, waist and knee pain, cold-damp arthralgia, metrorrhagia and bleeding, restless fetal movement, bruises, muscle fractures, etc.
  • Cynomorium cynomorium has the effects of nourishing the kidneys, supporting yang, moistening the intestines and laxative. It is mainly used to treat kidney yang deficiency, impotence, cold essence, liver and kidney insufficiency, foot flaccidity and soft tendons, intestinal dryness and constipation.
  • Cistanche deserticola has the effects of nourishing the kidneys, supporting yang, moistening the intestines and laxative. It is mainly used to treat deficiency of kidney yang, insufficient essence and blood, impotence and premature ejaculation, cold uterus and infertility, soreness of waist and knees, flaccidity, dryness of intestines and constipation.
  • Yellow dog kidney has the effects of warming the kidneys and strengthening yang, replenishing essence and replenishing marrow. It is mainly used to treat kidney yang deficiency, impotence, cold sperm, lack of sperm and infertility.
  • the giant centipede has the effect of calming convulsions and extinguishing the wind.
  • Morinda officinalis has the effects of nourishing the kidneys, supporting yang, dispelling wind and removing dampness. It is mainly used to treat impotence, cold uterus and infertility, frequent urination, rheumatism, waist and knee pain, kidney deficiency, soreness and weakness in the waist and knees.
  • Cornus officinalis has the effects of nourishing the liver and kidneys, relieving astringency and fixing prolapse, and is used to treat dizziness and tinnitus, waist and knee pain, impotence and spermatorrhea, enuresis and frequent urination, uterine bleeding, profuse sweating, and internal heat to quench thirst.
  • Red peony root has the effects of clearing away heat and cooling blood, activating blood circulation and removing blood stasis. It is mainly used to treat spots caused by warm poison, blood-heat, vomiting, red and swollen eyes, carbuncles, sores, liver stagnation and hypochondriac pain, amenorrhea and dysmenorrhea, abdominal pain and bruises.
  • the present invention specially selects the above-mentioned Chinese medicinal materials and utilizes the synergistic effect of these medicinal materials to jointly achieve the effects of tonifying the kidneys and replenishing qi, eliminating dampness and dissipating swelling. It is guided by shredded tobacco and made into the form of cigarettes. It is inhaled through the lungs and enters the whole body. Under the joint effect, conditioning is achieved. physical effects.
  • the ingredients of cigarettes include:
  • Angelica 20g wolfberry 20g, Ganoderma lucidum 20g, fairy spleen 20g, yam 20g, cordyceps 20g, curculigo 20g, honeycomb 20g, Eucommia 30g, Achyranthes 20g, Dipsacus 30g, Cynomorium cynomorium 20g, Cistanche deserticola 20g, 1 yellow dog kidney , 4 large centipedes, 20g Morinda officinalis, 20g cornus, 60g red peony root, 20g licorice, 50g rock sugar, 100g shredded tobacco, 20g mint, 20g honeysuckle, 20g wild chrysanthemum, 20g dandelion, 20g purple ground bark, purple back day 20g sunflower seeds, 20g apocynum, 10g shiitake mushrooms, 10g hericium, 10g oyster mushroom, 10g cypress fungus, 10g Armillaria fungus, 10g white fungus, 10g
  • the preparation method is as follows:
  • step d Stir and mix the particles obtained in step b and the shredded tobacco obtained in step c, then add the Chinese herbal medicine rock sugar wine obtained in step a, and take it out after 7 days to obtain a mixture of shredded tobacco and Chinese herbal medicine;
  • step g Mix the Chinese herbal medicine mixture of shredded tobacco obtained in step d and the fungal polysaccharide probiotic enzyme obtained in step f. After mixing, seal and store it for 1 month. Take it out and dry it in the sun. Take the particles of more than 10 mesh and within 2 mm to obtain the mixture of Chinese patent shredded tobacco. In the empty cigarette pipe, you can get a new type of Chinese herbal nicotine-free cigarette.
  • the ingredients of cigarettes include:
  • Angelica 100g wolfberry 100g, Ganoderma lucidum 100g, fairy spleen 100g, yam 100g, cordyceps 100g, curculigo 100g, honeycomb 100g, eucommia 100g, Achyranthes 100g, Dipsacus 100g, Cynomorium 100g, Cistanche deserticola 100g, 3 yellow dog kidneys , 8 large centipedes, 100g Morinda officinalis, 100g cornus, 100g red peony root, 100g licorice, 100g rock sugar, 200g shredded tobacco, 50g mint, 50g honeysuckle, 50g wild chrysanthemum, 50g dandelion, 50g purple groundweed, purple back day 50g sunflower seeds, 50g apocynum, 20g shiitake mushrooms, 20g hericium, 20g oyster mushrooms, 20g cypress fungus, 20g Armillaria fungus, 20g white fungus, 20g matsu
  • the preparation method is the same as Example 1.
  • the ingredients of cigarettes include:
  • Angelica 20g wolfberry 20g, Ganoderma lucidum 20g, fairy spleen 20g, yam 20g, cordyceps 20g, curculigo 20g, honeycomb 20g, Eucommia 30g, Achyranthes 20g, Dipsacus 30g, Cynomorium cynomorium 20g, Cistanche deserticola 20g, 1 yellow dog kidney , 4 large centipedes, 20g Morinda officinalis, 20g cornus, 60g red peony root, 20g licorice, 50g rock sugar, 200g shredded tobacco, 50g mint, 50g honeysuckle, 50g wild chrysanthemum, 50g dandelion, 50g purple groundweed, purple back day 50g sunflower seeds, 50g apocynum, 10g shiitake mushrooms, 10g hericium, 10g oyster mushroom, 10g cypress fungus, 10g Armillaria fungus, 10g white fungus, 10g
  • the preparation method is the same as Example 1.
  • the new cigarette prepared in Example 3 was used to conduct an effect verification experiment.
  • mice were used to conduct toxicity experiments. 50 white mice were selected, weighing (20 ⁇ 2) g, half male and half male, and randomly divided into 2 groups, namely the blank control group.
  • the cigarettes of the present invention were prepared according to the method of Example 3. Put them in different rooms. In the room where the mice in the cigarette group of the present invention are placed, the cigarettes of the present invention are lit for one and a half hours every day for 30 consecutive days. The blank control group is not treated, and the reactions of the mice are observed and recorded every day.
  • mice in the cigarette group of the present invention had no abnormal behavior, no symptoms of poisoning, no abnormalities in behavior and appetite, and general physical signs were good, indicating that the cigarette of the present invention was safe and had no toxic or side effects.
  • the content of heavy metals in the cigarettes of the present invention was measured, and no heavy metal content was detected, indicating that the cigarettes of the present invention are non-toxic.
  • Case Li male, 60 years old, felt kidney deficiency and backache at the beginning of 2020. He started smoking cigarettes of the invention in May 2021, smoking 5-10 cigarettes a day. After 3 months, his kidney deficiency and backache were significantly improved.
  • Case Jiang female, 50 years old, was diagnosed with high blood pressure in 2011.
  • her high pressure was 220, accompanied by high blood sugar and abdominal distension.
  • the high pressure is reduced to 180, accompanied by a decrease in blood sugar, the appetite becomes better, and the quality of sleep is improved.
  • Case Tian female, 54 years old, was diagnosed with lung nodules in 2020. She started smoking cigarettes of the invention in March, smoking 5-10 cigarettes a day, and her lung CT test was normal after one month of smoking.
  • the case is Li, male, 65 years old, a smoker for 30 years, coughing and spitting frequently every day, accompanied by varicose veins, getting up late at night, and cirrhosis of the liver.
  • Case Zhou male, 58 years old, has smoked for 30 years. He started smoking cigarettes of the invention in 2021, smoking 5-10 cigarettes a day. After a month, his face became younger, there were fewer spots on his face, and he gave up smoking.
  • Case Zhao male, 56 years old, has smoked for more than 20 years. He started smoking cigarettes of the invention in 2021, smoking 5-10 cigarettes a day. After two months, he no longer wanted to smoke the original cigarettes. He stopped smoking cigarettes of the invention and was followed up for half a year. There are no signs of addiction to the cigarettes of the invention.
  • the cigarette of the present invention has a scientific and reasonable mix of raw materials, has the effects of removing tobacco poison and conditioning and improving the body, is not addictive, and is suitable for promotion and use.

Abstract

A novel nicotine-free Chinese herbal medicine cigarette and a preparation method therefor. The cigarette uses as a way to introduce the medicine tobacco leaves from which nicotine has been removed and smoking is the means for introducing the Chinese herbal medicine to alveolar cells.

Description

新型中草药无尼古丁香烟及其制备方法Novel Chinese herbal nicotine-free cigarette and preparation method thereof 技术领域Technical field
本发明属于新型香烟领域,具体涉及一种新型中草药无尼古丁香烟及其制备方法。The invention belongs to the field of new cigarettes, and specifically relates to a new type of Chinese herbal nicotine-free cigarette and its preparation method.
背景技术Background technique
影响国民健康的一大要素是吸烟,吸烟的危害很大,烟草中含有多种有毒物质。烟草燃烧时所产生的烟气中,约含有1000多种有害成分。其中,焦油、一氧化碳和尼古丁等是致命物质。焦油会降低纤毛净化空气的作用;一氧化碳与血红蛋白结合,会赶走氧气,导致人体缺氧;尼古丁的危害最大并且具有成瘾性。A major factor affecting national health is smoking. Smoking is very harmful. Tobacco contains a variety of toxic substances. The smoke produced when tobacco is burned contains about 1,000 harmful components. Among them, tar, carbon monoxide and nicotine are deadly substances. Tar will reduce the function of cilia in purifying the air; carbon monoxide will combine with hemoglobin and drive away oxygen, causing the body to become hypoxic; nicotine is the most harmful and addictive.
长期吸烟的危害性很大,主要有以下几个方面:(1)引发呼吸系统疾病。长期吸烟容易使呼吸道黏膜出现慢性炎症,严重时可能会出现充血、水肿、炎性分泌物渗出,甚至引起呼吸道黏膜出现结构的改变,从而导致支气管炎、慢性阻塞性肺疾病、慢性肺源性心脏病,以及支气管扩张症,甚至还会引起一些恶性肿瘤,比如肺癌等。(2)引发心脑血管疾病。长期吸烟者容易引发冠状动脉粥样硬化性心脏病、高血压病、脑血管病。(3)引发消化系统疾病。长期吸烟者容易触发胃酸分泌增多,而且能够抑制胰腺分泌碳酸氢钠,使十二指肠酸负荷增加,容易诱发胃炎、十二指肠球部溃疡,而且能够降低食管下括约肌张力,从而诱发反流性食管炎等。(4)引发其他问题。除了容易导致肺癌以外,还可能会导致引起喉癌、膀胱癌、舌癌、食道癌、子宫颈癌等。而且对于孕妇来说,烟草中的这些致癌物质会通过胎盘影响胎儿,使其子代的癌症发生率显著增高。Long-term smoking is very harmful, mainly in the following aspects: (1) Causes respiratory diseases. Long-term smoking can easily cause chronic inflammation of the respiratory mucosa. In severe cases, congestion, edema, inflammatory secretions may occur, and may even cause structural changes in the respiratory mucosa, leading to bronchitis, chronic obstructive pulmonary disease, and chronic pulmonary disease. Heart disease, as well as bronchiectasis, can even cause some malignant tumors, such as lung cancer. (2) Cause cardiovascular and cerebrovascular diseases. Long-term smokers are prone to coronary atherosclerotic heart disease, hypertension, and cerebrovascular disease. (3) Cause digestive system diseases. Long-term smokers can easily trigger increased gastric acid secretion, and can inhibit the secretion of sodium bicarbonate by the pancreas, increasing the acid load in the duodenum, easily inducing gastritis and duodenal bulb ulcers, and can reduce the tension of the lower esophageal sphincter, thus inducing reaction. Fluid esophagitis, etc. (4) Cause other problems. In addition to easily causing lung cancer, it may also cause laryngeal cancer, bladder cancer, tongue cancer, esophageal cancer, cervical cancer, etc. And for pregnant women, these carcinogens in tobacco will affect the fetus through the placenta, significantly increasing the incidence of cancer in their offspring.
技术问题technical problem
吸烟有害健康,然而由于烟草中的尼古丁具有成瘾性,长期吸烟导致产生烟瘾,很难抗拒传统香烟的诱惑,一步步的侵害身体。为了减少烟瘾,降低吸烟造成的危害,需要开发一些新的对人体健康影响小的香烟。Smoking is harmful to health. However, due to the addictive nature of nicotine in tobacco, long-term smoking leads to addiction. It is difficult to resist the temptation of traditional cigarettes, which damages the body step by step. In order to reduce the addiction to cigarettes and reduce the harm caused by smoking, it is necessary to develop some new cigarettes that have less impact on human health.
技术解决方案Technical solutions
本发明要解决的技术问题为:现有香烟在吸烟时会产生多种有害物质,危害人体健康的问题。The technical problem to be solved by the present invention is that existing cigarettes produce a variety of harmful substances when smoking and endanger human health.
本发明解决上述技术问题的技术方案为:提供了一种新型中草药无尼古丁香烟。上述香烟的组成包括:当归20-100g,枸杞20-100g,灵芝20-100g,仙灵脾20-100g,山药20-100g,冬虫夏草20-100g,仙茅20-100g,蜂房20-100g,杜仲30-100g,牛膝20-100g,续断30-100g,锁阳20-100g,肉苁蓉20-100g,黄狗肾1具-3具,大蜈蚣4条-8条,巴戟天20-100g,山萸肉20-100g,赤芍60-100g,甘草20-100g,冰糖50-100g,烟丝100-200g,薄荷20-50g,金银花20-50g,野菊花20-50g,蒲公英20-50g,紫花地丁20-50g,紫背天葵子20-50g,罗布麻20-50g,香菇10-20g、猴头菇10-20g、平菇10-20g、松柏树菌10-20g、蜜环菌10-20g、白木耳10-20g、松茸菌10-20g。The technical solution of the present invention to solve the above technical problems is to provide a new type of Chinese herbal nicotine-free cigarette. The composition of the above-mentioned cigarettes includes: 20-100g of angelica, 20-100g of wolfberry, 20-100g of ganoderma, 20-100g of fairy spleen, 20-100g of Chinese yam, 20-100g of cordyceps, 20-100g of curculigo, 20-100g of honeycomb, and eucommia ulmoides. 30-100g, Achyranthes bidentata 20-100g, Dipsacus Dipsacus 30-100g, Cynomorium cynomorium 20-100g, Cistanche deserticola 20-100g, 1-3 yellow dog kidneys, 4-8 giant centipedes, Morinda citrifolia 20-100g , cornus 20-100g, red peony root 60-100g, licorice 20-100g, rock sugar 50-100g, tobacco 100-200g, mint 20-50g, honeysuckle 20-50g, wild chrysanthemum 20-50g, dandelion 20-50g, 20-50g of Purpurea purpurea, 20-50g of Apophyllum semen, 20-50g of Apocynum, 10-20g of shiitake mushroom, 10-20g of Hericium erinaceus, 10-20g of Pleurotus ostreatus, 10-20g of cypress fungus, Armillaria fungus 10-20g, white fungus 10-20g, matsutake mushroom 10-20g.
优选的,上述新型中草药无尼古丁香烟中,组成包括:当归20g,枸杞20g,灵芝20g,仙灵脾20g,山药20g,冬虫夏草20g,仙茅20g,蜂房20g,杜仲30g,牛膝20g,续断30g,锁阳20g,肉苁蓉20g,黄狗肾1具,大蜈蚣4条,巴戟天20g,山萸肉20g,赤芍60g,甘草20g,冰糖50g,烟丝200g,薄荷50g,金银花50g,野菊花50g,蒲公英50g,紫花地丁50g,紫背天葵子50g,罗布麻50g,香菇10g、猴头菇10g、平菇10g、松柏树菌10g、蜜环菌10g、白木耳10g、松茸菌10g。Preferably, the composition of the above-mentioned new Chinese herbal nicotine-free cigarettes includes: 20g Angelica sinensis, 20g Lycium barbarum, 20g Ganoderma lucidum, 20g Xianlingpi, 20g Chinese yam, 20g Cordyceps sinensis, 20g curculigo, 20g honeycomb, 30g Eucommia ulmoides, 20g Dipsacus root. 30g, 20g Cynomorium Cynomorium, 20g Cistanche deserticola, 1 yellow dog kidney, 4 large centipedes, 20g Morinda officinalis, 20g cornus, 60g red peony root, 20g licorice, 50g rock sugar, 200g shredded tobacco, 50g mint, 50g honeysuckle, wild 50g of chrysanthemum, 50g of dandelion, 50g of purpurea, 50g of hemp seed, 50g of apocynum, 10g of shiitake mushroom, 10g of hericium, 10g of oyster mushroom, 10g of cypress fungus, 10g of Armillaria fungus, 10g of white fungus, 10g of matsutake mushroom .
本发明还提供了一种上述新型中草药无尼古丁香烟的制备方法,包括以下步骤:The invention also provides a preparation method for the above-mentioned novel Chinese herbal nicotine-free cigarette, which includes the following steps:
a、将配方量的当归,枸杞,灵芝,山药,仙灵脾,冬虫夏草,仙茅,蜂房,杜仲,牛膝,续断,锁阳,肉苁蓉,黄狗肾,大蜈蚣,巴戟天,山萸肉,赤芍,甘草洗净晒干切段,泡制在45-50度粮食酒里,泡制2-3个月,得中草药酒,再加入冰糖得中草药冰糖酒;a. Add the formula amount of angelica, wolfberry, ganoderma, yam, fairy spleen, cordyceps, curculigo, hibiscus, eucommia, achyranthes, Dipsacus, Cynomorium, Cistanche deserticola, yellow dog kidney, giant centipede, Morinda officinalis, mountain Wash the cornus, red peony root and licorice, dry and cut into sections, soak in 45-50 degree grain wine, brew for 2-3 months to get Chinese herbal wine, then add rock sugar to get Chinese herbal rock sugar wine;
b、将配方量的薄荷,金银花,野菊花,蒲公英,紫花地丁,紫背天葵子,罗布麻粉碎成颗粒,取10目以上2毫米以下的颗粒备用;b. Crush the formula amount of peppermint, honeysuckle, wild chrysanthemum, dandelion, purpurea, geranium seed, and apocynum into granules, and take the granules with more than 10 mesh and less than 2 mm for later use;
c、将配方量的烟丝蒸馏30-40min后加入微生物恶臭假单胞菌封存1-2个月,得去尼古丁的烟丝;c. Distill the prescribed amount of cut tobacco for 30-40 minutes, add the microorganism Pseudomonas putida, and seal it for 1-2 months to obtain nicotine-free cut tobacco;
d、将步骤b所得颗粒与步骤c所得烟丝搅拌混匀后,加入步骤a所得中草药冰糖酒中,7-10天后取出,得烟丝中草药混合物;d. Stir and mix the particles obtained in step b and the shredded tobacco obtained in step c, then add the Chinese herbal medicine rock sugar wine obtained in step a, and take it out after 7-10 days to obtain a mixture of shredded tobacco and Chinese herbal medicine;
e、取配方量的香菇、猴头菇、平菇、松柏树菌、蜜环菌、白木耳、松茸菌,粉碎破壁,得复合真菌多糖;e. Take the formula amount of shiitake mushrooms, Hericium erinaceus, Pleurotus ostreatus, conifer fungus, Armillaria fungi, white fungus, and matsutake mushrooms, crush and break the wall to obtain the composite fungal polysaccharide;
f、取梨、葡萄、苹果、芒果,制成果汁,将步骤e中的复合真菌多糖倒入果汁中,复合真菌多糖与果汁的体积比为1:3-5,装罐密封保存1-2个月,得真菌多糖益生菌酵素;f. Take pears, grapes, apples, and mangoes to make juice. Pour the compound fungal polysaccharide in step e into the juice. The volume ratio of the compound fungal polysaccharide to the juice is 1:3-5. Store it in a can and seal for 1-2 Months, get fungal polysaccharide probiotic enzyme;
g、将步骤d所得烟丝中草药混合物与步骤f所得真菌多糖益生菌酵素,混合后密封保存1-2个月,取出后晒干,取10目以上2毫米以内的颗粒,得中成药烟丝混合物,装入空烟管中,得新型中草药无尼古丁香烟。g. Mix the Chinese herbal medicine mixture of shredded tobacco obtained in step d and the fungal polysaccharide probiotic enzyme obtained in step f, seal and store it for 1-2 months, take it out and dry it in the sun, and take the particles of more than 10 mesh and within 2 mm to obtain a mixture of Chinese patent shredded tobacco. Put it into an empty cigarette tube to get a new type of Chinese herbal nicotine-free cigarette.
其中,步骤a中,所述粮食酒的用量是步骤a药材总量的2-5倍。Wherein, in step a, the dosage of the grain wine is 2-5 times the total amount of medicinal materials in step a.
其中,步骤c中,所述微生物恶臭假单胞菌加入量为烟丝用量的10-20%。Wherein, in step c, the added amount of the microorganism Pseudomonas putida is 10-20% of the amount of shredded tobacco.
其中,步骤c中,所述微生物恶臭假单胞菌的浓度为5-20%。Wherein, in step c, the concentration of the microorganism Pseudomonas putida is 5-20%.
有益效果beneficial effects
本发明提供了一种新型中草药无尼古丁香烟及其制备方法,以去尼古丁的烟叶为药引,将对人体各项技能有益的中草药发酵产生的有益成分透过吸烟的方式吸入到肺里,因为肺通百脉,肺主气,心主血,气推血走,血随气行,气雾携带各种中草药的有效成分渗透到人体的五脏六腑、身体的各个经络和细胞将造成人体得病的湿气、寒气和毒素排出来并打通人体瘀堵的地方,让人体的各个部位能正常的运转,达到调理百病的效果。本发明的新型中草药无尼古丁香烟具有香烟的外形和抽吸方式,具有烟叶,吸起来有吸烟的感觉,但由于不含尼古丁,不会产生烟瘾,反而会降低烟瘾,同时通过抽吸的方式将中草药带入肺泡细胞中,改善肺泡细胞形态,达到调理身体的效果。The invention provides a new type of Chinese herbal medicine nicotine-free cigarette and a preparation method thereof. The nicotine-free tobacco leaves are used as the medicine, and the beneficial ingredients produced by the fermentation of Chinese herbal medicines that are beneficial to various human skills are inhaled into the lungs through smoking, because The lungs connect hundreds of meridians, the lungs govern qi, the heart governs blood, qi pushes the blood away, and the blood moves with the qi. The aerosol carries the active ingredients of various Chinese herbal medicines and penetrates into the internal organs, various meridians and cells of the body, which will cause the body to get sick. Moisture, coldness and toxins are discharged and the blocked areas of the human body are opened up, allowing all parts of the human body to function normally, achieving the effect of regulating all diseases. The new Chinese herbal nicotine-free cigarette of the present invention has the appearance and smoking method of a cigarette, and has tobacco leaves. It feels like smoking when smoked. However, because it does not contain nicotine, it will not cause cigarette addiction, but will reduce the cigarette craving. At the same time, it will be smoked through smoking. Chinese herbal medicine is brought into the alveolar cells to improve the morphology of the alveolar cells and achieve the effect of regulating the body.
本发明选择多种润肺中草药共同制备一种中草药无尼古丁香烟,以去尼古丁的烟叶为药引,通过吸烟的方式吸入到肺里,因为肺通百脉,肺主气,心主血,气推血走,血随气行,气雾携带各种中草药的有效成分渗透到人体的五脏六腑、身体的各个经络和细胞将造成人体得病的湿气、寒气和毒素排出来并打通人体瘀堵的地方,让人体的各个部位能正常的运转,达到调理百病的效果。The present invention selects a variety of lung-moistening Chinese herbal medicines to jointly prepare a Chinese herbal nicotine-free cigarette. The nicotine-free tobacco leaves are used as the drug guide, and are inhaled into the lungs through smoking, because the lungs connect hundreds of meridians, the lungs govern qi, the heart governs blood, and qi. Pushing the blood away, the blood follows the flow of Qi. The aerosol carries the active ingredients of various Chinese herbal medicines and penetrates into the human body's internal organs, various meridians and cells, expelling the moisture, cold air and toxins that cause the human body to become sick, and opening up the body's stasis and blockage. This place allows all parts of the human body to function normally and achieves the effect of regulating various diseases.
本发明选择的中药材中,当归补血活血,调经止痛,润肠通便;主治血虚萎黄,月经不调,经闭痛经,血虚,血滞,血寒诸痛,跌打损伤,风湿痹痛,痈疽疮疡,肠燥便秘等。Among the Chinese medicinal materials selected in the present invention, Angelica sinensis nourishes blood and activates blood circulation, regulates menstruation and relieves pain, moistens the intestines and relieves constipation; it is mainly used to treat blood deficiency and chlorosis, irregular menstruation, amenorrhea and dysmenorrhea, blood deficiency, blood stagnation, cold blood and various pains, bruises and rheumatic paralysis. Pain, ulcers, ulcers, intestinal dryness, constipation, etc.
枸杞滋补肝肾,益精明目,主治肝肾阴虚及早衰证。Lycium barbarum nourishes the liver and kidneys, replenishes essence and improves eyesight, and is mainly used to treat liver and kidney yin deficiency and premature aging.
灵芝补气安神,止咳平喘,主治心神不宁,咳喘痰多,虚劳症。Ganoderma lucidum nourishes qi and calms the mind, relieves cough and asthma, and is mainly used to treat restlessness, cough and asthma with excessive phlegm, and fatigue syndrome.
仙灵脾具有补肾强心,壮阳通痹的功效。用于阳萎遗精,筋骨痿软,胸闷头晕,气短乏力,风湿痹痛等。Xianling spleen has the effects of nourishing the kidneys and strengthening the heart, strengthening yang and relieving paralysis. It is used for impotence and spermatorrhea, weak muscles and bones, chest tightness and dizziness, shortness of breath and fatigue, rheumatic arthralgia, etc.
山药具有益气养阴,补脾肺肾,固精止带的功效。主治脾虚食少,倦怠乏力,便溏泄泻,肺虚喘咳,肾虚遗精,带下尿频,内热消渴等。Yam has the effects of replenishing qi and nourishing yin, nourishing the spleen, lungs and kidneys, strengthening essence and stopping vaginal discharge. Indications: Spleen deficiency, less food, fatigue, loose stools and diarrhea, lung deficiency, asthma and cough, kidney deficiency, spermatorrhea, vaginal discharge, frequent urination, internal heat and thirst, etc.
冬虫夏草具有补肾益肺,止血化痰的功效。主治阳痿遗精、腰膝酸痛、久咳虚喘、劳嗽痰血。Cordyceps sinensis has the effects of nourishing the kidneys and lungs, stopping bleeding and reducing phlegm. It is mainly used to treat impotence and spermatorrhea, soreness of waist and knees, chronic cough, shortness of breath, and labor cough with bloody phlegm.
仙茅具有温肾壮阳,祛寒除湿的功效。主治阳痿精寒,遗尿尿频,寒湿痹痛,筋骨痿软,腹痛冷泻等。Curculigo has the effects of warming the kidneys and strengthening yang, dispelling cold and dehumidifying. It is mainly used to treat impotence, cold essence, enuresis and frequent urination, cold-damp arthralgia, weakness of muscles and bones, abdominal pain, cold diarrhea, etc.
蜂房具有攻毒杀虫,祛风止痛的功效。主治痈疽,疔疮,瘰疬疥癣,瘾疹瘙痒,风湿痹痛,牙痛,喉痹肿痛等。The hive has the effects of attacking poisons and killing insects, dispelling wind and relieving pain. Mainly used to treat carbuncle, boils, scrofula, scabies, rash and itching, rheumatic arthralgia, toothache, sore throat, etc.
杜仲具有补肝肾,强筋骨,安胎的功效。主治肾虚腰痛及各种腰痛,胎动不安,习惯性堕胎。Eucommia ulmoides has the effects of nourishing the liver and kidneys, strengthening muscles and bones, and preventing miscarriage. It is mainly used to treat low back pain due to kidney deficiency and various low back pains, restless fetal movements, and habitual abortion.
牛膝具有活血通经,补肝肾,强筋骨,利水通淋,引火(血)下行的功效。主治瘀血阻滞经闭、痛经、经行腹痛、胞衣不下,跌打伤痛,腰膝酸痛,下肢痿软,淋证,水肿,小便不利,头痛,眩晕,齿痛,口舌生疮,吐血,衄血。Achyranthes bidentata has the effects of promoting blood circulation and promoting menstruation, nourishing the liver and kidneys, strengthening the muscles and bones, diluting water and relieving stranguria, and inducing the downward movement of fire (blood). Mainly used to treat blood stasis, amenorrhea, dysmenorrhea, abdominal pain during menstruation, retained afterbirth, pain from bruises, waist and knee pain, flaccidity of lower limbs, stranguria, edema, difficulty urinating, headache, dizziness, toothache, sores on the mouth and tongue, and vomiting blood. , epistaxis.
续断具有补益肝肾,续筋健骨,通利血脉的功效。主治肝肾不足,腰膝酸痛,寒湿痹痛,崩漏下血,胎动不安,跌打损伤,筋骨折伤等。Dipsacus has the effects of nourishing the liver and kidneys, strengthening muscles and bones, and promoting blood vessels. It is mainly used to treat liver and kidney deficiency, waist and knee pain, cold-damp arthralgia, metrorrhagia and bleeding, restless fetal movement, bruises, muscle fractures, etc.
锁阳具有补肾助阳,润肠通便的功效。主治肾阳虚衰,阳痿精冷,肝肾不足,足痿筋软,肠燥便秘等。Cynomorium cynomorium has the effects of nourishing the kidneys, supporting yang, moistening the intestines and laxative. It is mainly used to treat kidney yang deficiency, impotence, cold essence, liver and kidney insufficiency, foot flaccidity and soft tendons, intestinal dryness and constipation.
肉苁蓉具有补肾助阳,润肠通便的功效。主治肾阳亏虚,精血不足,阳痿早泄,宫冷不育,腰膝酸痛,痿软无力,肠燥津枯便秘。Cistanche deserticola has the effects of nourishing the kidneys, supporting yang, moistening the intestines and laxative. It is mainly used to treat deficiency of kidney yang, insufficient essence and blood, impotence and premature ejaculation, cold uterus and infertility, soreness of waist and knees, flaccidity, dryness of intestines and constipation.
黄狗肾具有暖肾壮阳,益精填髓的功效。主治肾阳虚衰,阳痿精冷,精少不育等。Yellow dog kidney has the effects of warming the kidneys and strengthening yang, replenishing essence and replenishing marrow. It is mainly used to treat kidney yang deficiency, impotence, cold sperm, lack of sperm and infertility.
大蜈蚣具有镇惊熄风之功效。主治破伤风,腰脊反张,四肢僵直,牙噤口喁,遍身冷,不知人者。临床上用于治疗疗疮肿毒、无名肿痛、急性乳腺炎、淋巴结核、骨髓炎、烧烫伤等。The giant centipede has the effect of calming convulsions and extinguishing the wind. Mainly used to treat tetanus, opisthotonosis of the waist and spine, stiffness of the limbs, clenched teeth, coldness all over the body, and ignorance of others. It is clinically used to treat sores, nameless swelling and pain, acute mastitis, lymph node tuberculosis, osteomyelitis, burns and scalds, etc.
巴戟天具有补肾助阳,祛风除湿的功效。主治阳痿不举,宫冷不孕,小便频数,风湿腰膝疼痛,肾虚腰膝酸软。Morinda officinalis has the effects of nourishing the kidneys, supporting yang, dispelling wind and removing dampness. It is mainly used to treat impotence, cold uterus and infertility, frequent urination, rheumatism, waist and knee pain, kidney deficiency, soreness and weakness in the waist and knees.
山萸肉具有补益肝肾、收涩固脱的作用,用于治疗眩晕耳鸣、腰膝酸痛、阳痿遗精、遗尿尿频、崩漏带下、大汗虚脱、内热消渴。Cornus officinalis has the effects of nourishing the liver and kidneys, relieving astringency and fixing prolapse, and is used to treat dizziness and tinnitus, waist and knee pain, impotence and spermatorrhea, enuresis and frequent urination, uterine bleeding, profuse sweating, and internal heat to quench thirst.
赤芍具有清热凉血,活血祛瘀的功效。主治温毒发斑,血热吐衄,目赤肿痛,痈肿疮疡,肝郁胁痛,经闭痛经,癥瘕腹痛,跌打损伤。Red peony root has the effects of clearing away heat and cooling blood, activating blood circulation and removing blood stasis. It is mainly used to treat spots caused by warm poison, blood-heat, vomiting, red and swollen eyes, carbuncles, sores, liver stagnation and hypochondriac pain, amenorrhea and dysmenorrhea, abdominal pain and bruises.
本发明特别的选择上述中药材,利用这些药材的协同作用,共同达到补肾益气,消湿散肿等功效,通过烟丝引导,制成香烟形式,通过肺吸入而进入全身,共同作用下达到调理身体的效果。The present invention specially selects the above-mentioned Chinese medicinal materials and utilizes the synergistic effect of these medicinal materials to jointly achieve the effects of tonifying the kidneys and replenishing qi, eliminating dampness and dissipating swelling. It is guided by shredded tobacco and made into the form of cigarettes. It is inhaled through the lungs and enters the whole body. Under the joint effect, conditioning is achieved. physical effects.
下面将通过实施例对本发明的具体实施方式做进一步的解释说明,但不表示将本发明的保护范围限制在实施例所述范围内。The specific embodiments of the present invention will be further explained below through examples, but this does not mean that the protection scope of the present invention is limited to the scope described in the examples.
实施例Example 1   1 制备本发明的新型中草药无尼古丁香烟Preparation of novel Chinese herbal nicotine-free cigarettes of the present invention
香烟的成分包括:The ingredients of cigarettes include:
当归20g,枸杞20g,灵芝20g,仙灵脾20g,山药20g,冬虫夏草20g,仙茅20g,蜂房20g,杜仲30g,牛膝20g,续断30g,锁阳20g,肉苁蓉20g,黄狗肾1具,大蜈蚣4条,巴戟天20g,山萸肉20g,赤芍60g,甘草20g,冰糖50g,烟丝100g,薄荷20g,金银花20g,野菊花20g,蒲公英20g,紫花地丁20g,紫背天葵子20g,罗布麻20g,香菇10g、猴头菇10g、平菇10g、松柏树菌10g、蜜环菌10g、白木耳10g、松茸菌10g。Angelica 20g, wolfberry 20g, Ganoderma lucidum 20g, fairy spleen 20g, yam 20g, cordyceps 20g, curculigo 20g, honeycomb 20g, Eucommia 30g, Achyranthes 20g, Dipsacus 30g, Cynomorium cynomorium 20g, Cistanche deserticola 20g, 1 yellow dog kidney , 4 large centipedes, 20g Morinda officinalis, 20g cornus, 60g red peony root, 20g licorice, 50g rock sugar, 100g shredded tobacco, 20g mint, 20g honeysuckle, 20g wild chrysanthemum, 20g dandelion, 20g purple ground bark, purple back day 20g sunflower seeds, 20g apocynum, 10g shiitake mushrooms, 10g hericium, 10g oyster mushroom, 10g cypress fungus, 10g Armillaria fungus, 10g white fungus, 10g matsutake mushroom.
制备方法如下:The preparation method is as follows:
a、将配方量的当归,枸杞,灵芝,山药,仙灵脾,冬虫夏草,仙茅,蜂房,杜仲,牛膝,续断,锁阳,肉苁蓉,黄狗肾,大蜈蚣,巴戟天,山萸肉,赤芍,甘草洗净晒干切段,泡制在45度粮食酒里,泡制2个月,得中草药酒,再加入冰糖得中草药冰糖酒;a. Add the formula amount of angelica, wolfberry, ganoderma, yam, fairy spleen, cordyceps, curculigo, hibiscus, eucommia, achyranthes, Dipsacus, Cynomorium, Cistanche deserticola, yellow dog kidney, giant centipede, Morinda officinalis, mountain Wash cornus, red peony root and licorice, dry and cut into sections, soak in 45 degree grain wine, brew for 2 months to get Chinese herbal wine, then add rock sugar to get Chinese herbal rock sugar wine;
b、将配方量的薄荷,金银花,野菊花,蒲公英,紫花地丁,紫背天葵子,罗布麻粉碎成颗粒,取10目以上2毫米以下的颗粒备用;b. Crush the formula amount of peppermint, honeysuckle, wild chrysanthemum, dandelion, purpurea, geranium seed, and apocynum into granules, and take the granules with more than 10 mesh and less than 2 mm for later use;
c、将配方量的烟丝蒸馏30min后加入微生物恶臭假单胞菌封存1个月,得去尼古丁的烟丝;c. Distill the formula amount of cut tobacco for 30 minutes, then add the microorganism Pseudomonas putida and seal it for 1 month to obtain nicotine-free cut tobacco;
d、将步骤b所得颗粒与步骤c所得烟丝搅拌混匀后,加入步骤a所得中草药冰糖酒中,7天后取出,得烟丝中草药混合物;d. Stir and mix the particles obtained in step b and the shredded tobacco obtained in step c, then add the Chinese herbal medicine rock sugar wine obtained in step a, and take it out after 7 days to obtain a mixture of shredded tobacco and Chinese herbal medicine;
e、取配方量的香菇、猴头菇、平菇、松柏树菌、蜜环菌、白木耳、松茸菌,粉碎破壁,得复合真菌多糖;e. Take the formula amount of shiitake mushrooms, Hericium erinaceus, Pleurotus ostreatus, conifer fungus, Armillaria fungi, white fungus, and matsutake mushrooms, crush and break the wall to obtain the composite fungal polysaccharide;
f、取梨、葡萄、苹果、芒果,制成果汁,将步骤e中的复合真菌多糖倒入果汁中,复合真菌多糖与果汁的体积比为1:3,装罐密封保存1个月,得真菌多糖益生菌酵素;f. Take pears, grapes, apples, and mangoes to make juice. Pour the compound fungal polysaccharide in step e into the juice. The volume ratio of the compound fungal polysaccharide to the juice is 1:3. Store it in a can and seal for 1 month to obtain Fungal polysaccharide probiotic enzyme;
g、将步骤d所得烟丝中草药混合物与步骤f所得真菌多糖益生菌酵素,混合后密封保存1个月,取出后晒干,取10目以上2毫米以内的颗粒,得中成药烟丝混合物,装入空烟管中,得新型中草药无尼古丁香烟。g. Mix the Chinese herbal medicine mixture of shredded tobacco obtained in step d and the fungal polysaccharide probiotic enzyme obtained in step f. After mixing, seal and store it for 1 month. Take it out and dry it in the sun. Take the particles of more than 10 mesh and within 2 mm to obtain the mixture of Chinese patent shredded tobacco. In the empty cigarette pipe, you can get a new type of Chinese herbal nicotine-free cigarette.
实施例Example 2   2 制备本发明的新型中草药无尼古丁香烟Preparation of novel Chinese herbal nicotine-free cigarettes of the present invention
香烟的成分包括:The ingredients of cigarettes include:
当归100g,枸杞100g,灵芝100g,仙灵脾100g,山药100g,冬虫夏草100g,仙茅100g,蜂房100g,杜仲100g,牛膝100g,续断100g,锁阳100g,肉苁蓉100g,黄狗肾3具,大蜈蚣8条,巴戟天100g,山萸肉100g,赤芍100g,甘草100g,冰糖100g,烟丝200g,薄荷50g,金银花50g,野菊花50g,蒲公英50g,紫花地丁50g,紫背天葵子50g,罗布麻50g,香菇20g、猴头菇20g、平菇20g、松柏树菌20g、蜜环菌20g、白木耳20g、松茸菌20g。Angelica 100g, wolfberry 100g, Ganoderma lucidum 100g, fairy spleen 100g, yam 100g, cordyceps 100g, curculigo 100g, honeycomb 100g, eucommia 100g, Achyranthes 100g, Dipsacus 100g, Cynomorium 100g, Cistanche deserticola 100g, 3 yellow dog kidneys , 8 large centipedes, 100g Morinda officinalis, 100g cornus, 100g red peony root, 100g licorice, 100g rock sugar, 200g shredded tobacco, 50g mint, 50g honeysuckle, 50g wild chrysanthemum, 50g dandelion, 50g purple groundweed, purple back day 50g sunflower seeds, 50g apocynum, 20g shiitake mushrooms, 20g hericium, 20g oyster mushrooms, 20g cypress fungus, 20g Armillaria fungus, 20g white fungus, 20g matsutake mushroom.
制备方法同实施例1。The preparation method is the same as Example 1.
实施例Example 3   3 制备本发明的新型中草药无尼古丁香烟Preparation of novel Chinese herbal nicotine-free cigarettes of the present invention
香烟的成分包括:The ingredients of cigarettes include:
当归20g,枸杞20g,灵芝20g,仙灵脾20g,山药20g,冬虫夏草20g,仙茅20g,蜂房20g,杜仲30g,牛膝20g,续断30g,锁阳20g,肉苁蓉20g,黄狗肾1具,大蜈蚣4条,巴戟天20g,山萸肉20g,赤芍60g,甘草20g,冰糖50g,烟丝200g,薄荷50g,金银花50g,野菊花50g,蒲公英50g,紫花地丁50g,紫背天葵子50g,罗布麻50g,香菇10g、猴头菇10g、平菇10g、松柏树菌10g、蜜环菌10g、白木耳10g、松茸菌10g。Angelica 20g, wolfberry 20g, Ganoderma lucidum 20g, fairy spleen 20g, yam 20g, cordyceps 20g, curculigo 20g, honeycomb 20g, Eucommia 30g, Achyranthes 20g, Dipsacus 30g, Cynomorium cynomorium 20g, Cistanche deserticola 20g, 1 yellow dog kidney , 4 large centipedes, 20g Morinda officinalis, 20g cornus, 60g red peony root, 20g licorice, 50g rock sugar, 200g shredded tobacco, 50g mint, 50g honeysuckle, 50g wild chrysanthemum, 50g dandelion, 50g purple groundweed, purple back day 50g sunflower seeds, 50g apocynum, 10g shiitake mushrooms, 10g hericium, 10g oyster mushroom, 10g cypress fungus, 10g Armillaria fungus, 10g white fungus, 10g matsutake mushroom.
制备方法同实施例1。The preparation method is the same as Example 1.
采用实施例3制备的新型烟进行效果验证实验。The new cigarette prepared in Example 3 was used to conduct an effect verification experiment.
采用小鼠进行毒性实验,选取小白鼠50只,体重(20±2)g,雌雄各半,随机平均分为2组,即空白对照组,本发明香烟按照实施例3的方法进行制备组,分别放在不同的房间。在放置本发明香烟组小鼠的房间每日点燃本发明香烟一个半个小时,连续30天,空白对照组不做处理,每日观察记录小鼠反应。结果表明:与空白对照组相比,本发明香烟组小鼠行为无异常,无中毒症状,行为,食欲均无异常,一般体征良好,表明本发明香烟安全、无毒副作用。Mice were used to conduct toxicity experiments. 50 white mice were selected, weighing (20±2) g, half male and half male, and randomly divided into 2 groups, namely the blank control group. The cigarettes of the present invention were prepared according to the method of Example 3. Put them in different rooms. In the room where the mice in the cigarette group of the present invention are placed, the cigarettes of the present invention are lit for one and a half hours every day for 30 consecutive days. The blank control group is not treated, and the reactions of the mice are observed and recorded every day. The results showed that compared with the blank control group, the mice in the cigarette group of the present invention had no abnormal behavior, no symptoms of poisoning, no abnormalities in behavior and appetite, and general physical signs were good, indicating that the cigarette of the present invention was safe and had no toxic or side effects.
测定本发明香烟中的重金属含量,均未检出,提示本发明香烟无毒性。The content of heavy metals in the cigarettes of the present invention was measured, and no heavy metal content was detected, indicating that the cigarettes of the present invention are non-toxic.
采用实施例3的香烟进行临床实验:Use the cigarettes of Example 3 to conduct clinical experiments:
病例李某,男,60岁,2020年初感觉肾虚,腰酸背痛2021年5月开始吸本发明香烟,每天吸5-10支,3个月后,肾虚,腰酸背痛情况明显改善。Case Li, male, 60 years old, felt kidney deficiency and backache at the beginning of 2020. He started smoking cigarettes of the invention in May 2021, smoking 5-10 cigarettes a day. After 3 months, his kidney deficiency and backache were significantly improved.
病例肖某,女,45岁,2015年11月诊断出是糖尿病同时诊断高血压,之前身全四肢无力浮肿没精神、视力模糊、吃糖降降压药,吸本发明香烟20天,每天吸5-10支,一身浮肿好转、精力充沛,视力提高。Case: Xiao, female, 45 years old, was diagnosed with diabetes and high blood pressure in November 2015. Previously, her body and limbs were weak, swollen, lack of energy, blurred vision, taking sugar and antihypertensive drugs, and smoked cigarettes of the present invention for 20 days, every day. 5-10 sticks, the edema all over the body will improve, you will be energetic and your eyesight will improve.
病例姜某,女,50岁,2011年诊断出来高血压,2021年6月开始吸本发明香烟时高压220,伴随高血糖,腹胀。吸本发明香烟一个月,每天吸5-10支,高压降至180,同时伴随血糖下降,胃口变好,睡眠质量得以改善。Case Jiang, female, 50 years old, was diagnosed with high blood pressure in 2011. When she started smoking cigarettes of the invention in June 2021, her high pressure was 220, accompanied by high blood sugar and abdominal distension. After smoking cigarettes of the present invention for one month, 5-10 cigarettes a day, the high pressure is reduced to 180, accompanied by a decrease in blood sugar, the appetite becomes better, and the quality of sleep is improved.
病例田某,女,54岁,2020年诊断出肺有结节,3月开始吸本发明香烟,每天吸5-10支,吸一个月后肺CT检测正常。Case Tian, female, 54 years old, was diagnosed with lung nodules in 2020. She started smoking cigarettes of the invention in March, smoking 5-10 cigarettes a day, and her lung CT test was normal after one month of smoking.
病例李某,男,65岁,有30年烟龄,每天都频繁的咳嗽吐痰,伴随有静脉曲张,老起夜,肝硬化。从2020年开始吸本发明香烟每天吸5-10支,三个月后不再咳嗽吐痰了,静脉曲张没有了,晚上睡觉不再起夜了,肝硬化指标没有继续恶化,同时戒除了烟瘾。The case is Li, male, 65 years old, a smoker for 30 years, coughing and spitting frequently every day, accompanied by varicose veins, getting up late at night, and cirrhosis of the liver. I started smoking 5-10 cigarettes of the invention every day in 2020. After three months, I stopped coughing and spitting, my varicose veins disappeared, I stopped getting up late at night, my liver cirrhosis indicators did not continue to worsen, and I quit smoking at the same time.
病例周某,男,58岁,有30年烟龄,2021年开始吸本发明香烟,每天吸5-10支,一个月后脸上变年轻,脸上的斑点少了,戒除了烟瘾。Case Zhou, male, 58 years old, has smoked for 30 years. He started smoking cigarettes of the invention in 2021, smoking 5-10 cigarettes a day. After a month, his face became younger, there were fewer spots on his face, and he gave up smoking.
病例赵某,男,56岁,有20多年烟龄,2021年开始吸本发明香烟,每天吸5-10支,两个月后不再想吸原来的香烟,停吸本发明香烟跟踪半年后并无对本发明香烟上瘾的迹象。Case Zhao, male, 56 years old, has smoked for more than 20 years. He started smoking cigarettes of the invention in 2021, smoking 5-10 cigarettes a day. After two months, he no longer wanted to smoke the original cigarettes. He stopped smoking cigarettes of the invention and was followed up for half a year. There are no signs of addiction to the cigarettes of the invention.
综上所述,本发明香烟原料搭配科学合理,具有去烟毒和调理改善身体的功效,且不上瘾,适宜推广使用。To sum up, the cigarette of the present invention has a scientific and reasonable mix of raw materials, has the effects of removing tobacco poison and conditioning and improving the body, is not addictive, and is suitable for promotion and use.

Claims (4)

  1. 新型中草药无尼古丁香烟的制备方法,其特征在于,包括以下步骤:The preparation method of new Chinese herbal nicotine-free cigarettes is characterized by including the following steps:
    新型中草药无尼古丁香烟组成包括:当归20-100g,枸杞20-100g,灵芝20-100g,仙灵脾20-100g,山药20-100g,冬虫夏草20-100g,仙茅20-100g,蜂房20-100g,杜仲30-100g,牛膝20-100g,续断30-100g,锁阳20-100g,肉苁蓉20-100g,黄狗肾1具-3具,大蜈蚣4条-8条,巴戟天20-100g,山萸肉20-100g,赤芍60-100g,甘草20-100g,冰糖50-100g,烟丝100-200g,薄荷20-50g,金银花20-50g,野菊花20-50g,蒲公英20-50g,紫花地丁20-50g,紫背天葵子20-50g,罗布麻20-50g,香菇10-20g,猴头菇10-20g,平菇10-20g,松柏树菌10-20g,蜜环菌10-20g,白木耳10-20g,松茸菌10-20g;The composition of the new Chinese herbal nicotine-free cigarettes includes: Angelica sinensis 20-100g, wolfberry 20-100g, Ganoderma lucidum 20-100g, Xianlingpi 20-100g, yam 20-100g, Cordyceps sinensis 20-100g, curculigo 20-100g, honeycomb 20-100g , Eucommia 30-100g, Achyranthes bidentata 20-100g, Dipsacus Dipsacus 30-100g, Cynomorium cynomorium 20-100g, Cistanche deserticola 20-100g, 1-3 yellow dog kidneys, 4-8 giant centipedes, 20 Morinda officinalis -100g, cornus 20-100g, red peony root 60-100g, licorice 20-100g, rock sugar 50-100g, tobacco 100-200g, mint 20-50g, honeysuckle 20-50g, wild chrysanthemum 20-50g, dandelion 20- 50g, 20-50g of Purpurea purpurea, 20-50g of Apophyllum semen, 20-50g of Apocynum, 10-20g of shiitake mushroom, 10-20g of Hericium erinaceus, 10-20g of oyster mushroom, 10-20g of cypress fungus, honey 10-20g of ring fungus, 10-20g of white fungus, 10-20g of matsutake mushroom;
    a、将配方量的当归,枸杞,灵芝,山药,仙灵脾,冬虫夏草,仙茅,蜂房,杜仲,牛膝,续断,锁阳,肉苁蓉,黄狗肾,大蜈蚣,巴戟天,山萸肉,赤芍,甘草洗净晒干切段,泡制在45-50度粮食酒里,泡制2-3个月,得中草药酒,再加入冰糖得中草药冰糖酒;a. Add the formula amount of angelica, wolfberry, ganoderma, yam, fairy spleen, cordyceps, curculigo, hibiscus, eucommia, achyranthes, Dipsacus, Cynomorium, Cistanche deserticola, yellow dog kidney, giant centipede, Morinda officinalis, mountain Wash the cornus, red peony root and licorice, dry and cut into sections, soak in 45-50 degree grain wine, brew for 2-3 months to get Chinese herbal wine, then add rock sugar to get Chinese herbal rock sugar wine;
    b、将配方量的薄荷,金银花,野菊花,蒲公英,紫花地丁,紫背天葵子,罗布麻粉碎成颗粒,取10目以上2毫米以下的颗粒备用;b. Crush the formula amount of peppermint, honeysuckle, wild chrysanthemum, dandelion, purpurea, geranium seed, and apocynum into granules, and take the granules with more than 10 mesh and less than 2 mm for later use;
    c、将配方量的烟丝蒸馏30-40min后加入微生物恶臭假单胞菌封存1-2个月,得去尼古丁的烟丝;c. Distill the prescribed amount of cut tobacco for 30-40 minutes, add the microorganism Pseudomonas putida, and seal it for 1-2 months to obtain nicotine-free cut tobacco;
    d、将步骤b所得颗粒与步骤c所得烟丝搅拌混匀后,加入步骤a所得中草药冰糖酒中,7-10天后取出,得烟丝中草药混合物;d. Stir and mix the particles obtained in step b and the shredded tobacco obtained in step c, then add the Chinese herbal medicine rock sugar wine obtained in step a, and take it out after 7-10 days to obtain a mixture of shredded tobacco and Chinese herbal medicine;
    e、取配方量的香菇、猴头菇、平菇、松柏树菌、蜜环菌、白木耳、松茸菌,粉碎破壁,得复合真菌多糖;e. Take the formula amount of shiitake mushrooms, Hericium erinaceus, Pleurotus ostreatus, conifer fungus, Armillaria fungi, white fungus, and matsutake mushrooms, crush and break the wall to obtain the composite fungal polysaccharide;
    f、取梨、葡萄、苹果、芒果,制成果汁,将步骤e中的复合真菌多糖倒入果汁中,复合真菌多糖与果汁的体积比为1:3-5,装罐密封保存1-2个月,得真菌多糖益生菌酵素;f. Take pears, grapes, apples, and mangoes to make juice. Pour the compound fungal polysaccharide in step e into the juice. The volume ratio of the compound fungal polysaccharide to the juice is 1:3-5. Store it in a can and seal for 1-2 Months, get fungal polysaccharide probiotic enzyme;
    g、将步骤d所得烟丝中草药混合物与步骤f所得真菌多糖益生菌酵素,混合后密封保存1-2个月,取出后晒干,取10目以上2毫米以内的颗粒,得中成药烟丝混合物,装入空烟管中,得新型中草药无尼古丁香烟。g. Mix the Chinese herbal medicine mixture of shredded tobacco obtained in step d and the fungal polysaccharide probiotic enzyme obtained in step f, seal and store it for 1-2 months, take it out and dry it in the sun, and take the particles of more than 10 mesh and within 2 mm to obtain a mixture of Chinese patent shredded tobacco. Put it into an empty cigarette tube to get a new type of Chinese herbal nicotine-free cigarette.
  2. 根据权利要求1所述的新型中草药无尼古丁香烟的制备方法,其特征在于:步骤a所述粮食酒的用量是步骤a药材总量的2-5倍。The preparation method of new Chinese herbal nicotine-free cigarettes according to claim 1, characterized in that: the amount of grain wine in step a is 2-5 times the total amount of medicinal materials in step a.
  3. 根据权利要求1所述的新型中草药无尼古丁香烟的制备方法,其特征在于:步骤c中所述微生物恶臭假单胞菌加入量为烟丝用量的10-20%。The preparation method of new Chinese herbal nicotine-free cigarettes according to claim 1, characterized in that: the addition amount of the microorganism Pseudomonas putida in step c is 10-20% of the amount of shredded tobacco.
  4. 根据权利要求1所述的新型中草药无尼古丁香烟的制备方法,其特征在于:步骤c中所述微生物恶臭假单胞菌的浓度为5-20%。The preparation method of new Chinese herbal nicotine-free cigarettes according to claim 1, characterized in that: the concentration of the microorganism Pseudomonas putida in step c is 5-20%.
PCT/CN2023/070044 2022-03-09 2023-01-03 Novel nicotine-free chinese herbal medicine cigarette and preparation method therefor WO2023169069A1 (en)

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