WO2023155177A1 - Sensitivity test management system and method - Google Patents

Sensitivity test management system and method Download PDF

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Publication number
WO2023155177A1
WO2023155177A1 PCT/CN2022/076974 CN2022076974W WO2023155177A1 WO 2023155177 A1 WO2023155177 A1 WO 2023155177A1 CN 2022076974 W CN2022076974 W CN 2022076974W WO 2023155177 A1 WO2023155177 A1 WO 2023155177A1
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information
sensitivity test
sensitivity
test management
management system
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PCT/CN2022/076974
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French (fr)
Chinese (zh)
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曹庆恒
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曹庆恒
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Priority to CN202280000208.6A priority Critical patent/CN117121117A/en
Priority to PCT/CN2022/076974 priority patent/WO2023155177A1/en
Publication of WO2023155177A1 publication Critical patent/WO2023155177A1/en

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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00ICT specially adapted for the handling or processing of medical references

Definitions

  • the invention relates to the technical field of intelligent medical information processing, in particular to a sensitivity test management system and method.
  • the existing sensitivity test is usually carried out before the doctor takes the medicine. In order to prevent the occurrence of allergic reactions, especially the occurrence of severe allergic reactions, it is stipulated that some drugs that are prone to allergic reactions need to be tested for skin sensitivity before use. If the skin test is negative Drugs can be given to patients, but are prohibited if the skin test is positive.
  • Existing sensitivity tests are usually only for specific drugs, and less consideration is given to patients and disease conditions, and the experimental results are mainly judged based on experience, lacking quantitative standards. At the same time, false positives in sensitive tests will affect accurate drug selection, which may lead to medication risks, over-medication and other problems, and may even delay the timely treatment of patients.
  • the main purpose of the present invention is to provide a sensitivity test management system and method for the current situation that the existing sensitivity test management is not refined enough, from the assessment of whether the sensitivity test is needed, the quantitative analysis of the experimental results, and the basis Management of sensitivity tests in various aspects, such as drug analysis of experimental results, is conducive to high-quality management of sensitivity tests, and plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.
  • the present invention provides a sensitivity test management system, said system comprising:
  • the database unit is used to store a sensitivity test management database, and the sensitivity test management database includes rules that require sensitivity tests;
  • An information acquisition unit configured to acquire patient information, disease information, and information on allergens to be tested, the allergens to be tested include: at least one of medicine, diet, medical equipment, light, cosmetics, daily necessities, air, and clothing;
  • the analysis unit is configured to perform analysis according to the patient information, disease information, allergen information to be tested and the rules requiring a sensitivity test to evaluate whether a sensitivity test is required.
  • the sensitivity test management database includes the rules of the sensitivity test scheme, and the sensitivity test management system provides a suitable sensitivity test for patients who need a sensitivity test plan.
  • the database unit further stores a patient personal information database, and the patient personal information database includes relevant information of the patient for providing or supplementing the patient information.
  • the sensitivity test management database includes rules for analysis of sensitivity test results
  • the sensitivity test management system obtains the data of the sensitivity test through the information acquisition unit
  • the analysis unit analyzes the data of the sensitivity test to obtain the result of the sensitivity test.
  • the analysis unit identifies the image data of the sensitivity test, and analyzes at least one of the data of the position, color, area, and height of the red and swollen part to obtain the sensitivity test the result of.
  • the sensitivity test management system evaluates according to the results of the sensitivity test and patient information, disease information, and allergen information to be tested, and gives the evaluation results.
  • the analysis unit is based on at least one of safety, effectiveness, economy, and suitability of the allergen to be tested under different conditions of patient information and disease information. For different analysis results of each analysis item, set the corresponding grades/scores respectively.
  • the substance evaluation model is used to calculate the comprehensive grade/score of different allergens to be tested.
  • the sensitivity test management system also optimizes and adjusts the patient's original application plan according to the evaluation results of the allergens to be tested.
  • the method of optimizing and adjusting the application plan may include: adjusting the use plan of the relevant test allergen, adjusting the relevant test allergen, carrying out the use monitoring of the relevant test allergen or other treatment methods, etc. at least one.
  • the present invention also provides a sensitivity test management method, the method comprising:
  • Step 1 establishing a sensitivity test management database, the sensitivity test management database includes rules that require sensitivity tests;
  • Step 2 obtaining patient information, disease information and allergen information to be tested
  • Step 3 Analyze according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.
  • the sensitivity test management system includes: a database unit, an information acquisition unit and an analysis unit.
  • Sensitivity test management methods include: establishing a sensitivity test management database, obtaining patient information, disease information, and test allergen information, and performing analysis based on patient information, disease information, test allergen information, and rules requiring sensitivity tests, Assess the need for sensitivity testing.
  • sensitivity test management is carried out from various aspects such as rules for sensitivity tests, quantitative analysis of test results, and analysis of allergens to be tested according to test results, which is beneficial High-quality management of sensitivity tests plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.
  • Fig. 1 is a block diagram of a susceptibility test management system of the present invention.
  • Fig. 2 is a flow chart of a sensitivity test management method of the present invention.
  • the sensitivity test includes skin (or intradermal) sensitivity test, and may also include other sensitivity tests.
  • Some drugs are prone to allergic reactions during clinical use, such as penicillin, streptomycin, cytochrome C, etc. Common allergic reactions include rash, urticaria, dermatitis, fever, angioedema, asthma, anaphylactic shock, etc. Among them, anaphylactic shock is the most serious and can even lead to death.
  • Drugs with negative skin tests can be given to patients, and those with positive skin tests are prohibited.
  • the allergens to be tested may include: drugs, diet, medical equipment, light, cosmetics, daily necessities, air, clothing, etc.
  • patients refer to the objects analyzed by the sensitivity test management system, which may include: sick people, medical examiners, pregnant women, children, personnel in special positions, subjects, etc., and may also be other groups of people who need to be tested for allergies.
  • Fig. 1 is a block diagram of a susceptibility test management system of the present invention.
  • a sensitivity test management system of the present invention includes:
  • Database unit 11 is used for storing sensitivity test management database, and described sensitivity test management database includes the rule that needs to do sensitivity test;
  • An information acquisition unit 12 configured to acquire patient information, disease information and allergen information to be tested;
  • the analysis unit 13 is configured to perform analysis according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.
  • the sensitivity test management database may include: rules requiring sensitivity tests, and may also include rules for sensitivity test schemes and rules for analysis of sensitivity test results. Specifically, it can include various related element attributes and their values/ranges/calculation methods/sources/restrictions/exclusions, and the interrelationships/interactions/transformations between various/groups/various element attributes /rule/calculation method.
  • the rule that requires a sensitivity test is based on a comprehensive judgment of patient information, disease information, and allergen information to be tested. If certain rules are met, a sensitivity test is required. For example: Some drugs require skin tests according to regulations; some drugs require skin tests only under specific circumstances, such as: those who are allergic to thymosin injection need to do skin tests. Since the occurrence of allergic reactions is closely related to the internal allergens of antibiotics and the patient's own allergic constitution, it is necessary to comprehensively consider the information of the patient, the disease, and the allergen to be tested to determine whether a sensitivity test is required, rather than Simply by using the allergens to be tested to determine whether a sensitivity test is required.
  • the sensitivity test management database and its contents of the present invention are based on various diagnosis and treatment standards, diagnosis and treatment norms, guidelines, industry norms, teaching materials, clinical treatment paths, drug instructions, medical equipment use/operation instructions, medical device instruction manuals, surgical operation specifications , inspection/inspection specifications, formulary, pharmacopoeia, expert consensus, expert experience, meeting minutes and consensus within the medical consortium/hospital/department, papers, monographs, inventions, scientific inferences, experimental reports, experimental reports, data analysis reports, Test reports, test reports, approval documents, relevant regulations, relevant guidance, relevant policies, relevant systems, relevant catalogs, relevant literature, relevant price regulations, relevant price catalogs, relevant bidding results, relevant price policies, relevant insurance payment terms, Relevant insurance payment agreements, relevant bidding results, relevant procurement catalogs, relevant doctors/nurses/examiners/pharmacists/nursing staff/patients/salespersons’ evaluations/test results/monitoring reports/safety reports, other literature, other professional/ Authoritative research results can also be
  • the sensitivity test management database can also be a database established by combining the above methods.
  • the database can be updated by version, or it can be updated in real time based on actual data.
  • the sensitivity test management database can be a relational database or a non-relational database; it can be a table database, a graph database, or a knowledge map database; relevant data can be structured data or unstructured data .
  • the rules related to the need for sensitivity test, the rules of the sensitivity test program and the rules of sensitivity test result analysis may include: various use conditions/requirements/attributes/ Numerical values, such as drug manufacturer, specification, dosage form, daily frequency, time interval, time/daily dosage, time/day maximum dosage, method of use, sensitivity, route of administration, site of administration, etc.
  • group information may include specific age, gender, developmental status, marital status, childbearing status, working status, learning status, exercise status, living status, physiological status, psychological status, genetic status, physical status, immune status and other specific population information.
  • Genetic related information includes: genetic information, genetic information variation/change information, genetic defect information, genetic medical history, family medical history and other information.
  • Disease information includes: disease, diagnosis, symptom, symptom type, symptom, index, pulse condition, tongue diagnosis and other information.
  • Medical history information includes medical history, surgical history, radiotherapy history, chemotherapy history, psychotherapy history, physical therapy history, immunotherapy history, gene therapy history, and other information.
  • Medication history information includes: medication history, drug efficacy, adverse drug reactions, drug allergy history, drug tolerance, and other information.
  • Medical device use history information includes: medical device use history, medical device efficacy, medical device adverse reactions, medical device tolerance, etc.
  • Operation items include surgery, inspection, inspection, test, detection, operation, health care, rehabilitation, psychological treatment, radiotherapy, chemotherapy, physical therapy, hyperthermia, phototherapy, magnetic therapy, electrotherapy, cold therapy, electromagnetic therapy, sound therapy, immunotherapy, Gene therapy, weight loss, fitness, plastic surgery, beauty and other projects.
  • Physiological development information includes: growth and development, physiological stage, fertility and other information.
  • Marriage information includes marriage history, birth history, sex life and other information.
  • Physiological conditions include: physical fitness, nutritional status, hearing, vision, taste, smell, touch, breathing, motor coordination, digestion, absorption, excretion, sexual function, etc. and the level of related abilities.
  • Mental/intellectual conditions include: mental illness, emotions, feelings, intelligence, attention, memory, perception, communication skills, expressive skills, etc.
  • Life/work/study/sports/entertainment information includes: diet, work and rest, sleep, work, study, entertainment, sports and other related information.
  • Environmental information includes: microbial distribution, contact population, temperature, humidity, air pressure, season, altitude, air quality, air diffusion conditions, terrain, landform, oxygen content, light, ultraviolet rays, radiation, electromagnetic waves, noise, epidemics, plant information.
  • Medical insurance related information includes medical benefits, medical insurance, commercial insurance, etc.
  • Medical institution information includes medical institution level, specialties, attributes, regions, departments and other information.
  • Medical personnel information includes: age, gender, position, professional title, professional qualifications, professional training, protective measures and other information.
  • Implants include: grafts, cultures, gene carriers, implanted chips, implanted equipment/devices, etc.
  • Nutritional support includes: water, calories, protein, trace elements, sugar, salt, fat, carbohydrates, minerals, amino acids, vitamin testing, content standards, supplementary dosage, etc.
  • the rules in the sensitivity test management database that require sensitivity tests, the rules of the sensitivity test program and the rules of the analysis of sensitivity test results can be established based on a single allergen to be tested or a classification of allergens to be tested, or It may include sections established for each test allergen group to be used in combination.
  • the rules of the sensitivity test scheme are the rules of adopting an appropriate sensitivity test scheme according to different patient information, disease information, and allergen information to be tested.
  • the sensitivity test management system provides a suitable sensitivity test plan for patients who need a sensitivity test based on patient information, disease information, information on allergens to be tested, and the rules of the sensitivity test plan.
  • the rules for the analysis of sensitivity test results are the rules for giving the results of sensitivity tests based on different patient information, disease information, information on allergens to be tested and sensitivity test data.
  • the sensitivity test management system obtains the data of the sensitivity test through the information acquisition unit, and analyzes the data of the sensitivity test through the analysis unit combining patient information, disease information, and allergen information to obtain the result of the sensitivity test.
  • the sensitivity test management database of the present invention can also include relevant information on allergic reactions of the allergens to be tested, such as: the relationship between the use method/dose/time/frequency/interval of the allergens to be tested and the allergic reaction, the possibility of the allergens to be tested Allergic reactions and the factors that may affect the allergic reactions and the treatment measures after the allergic reactions occur, specifically including: related influencing factors of allergic reactions, symptoms/indicator signals/manifestations/feelings/severity/harm of allergic reactions, allergic reactions Treatment, allergic reaction prevention methods, remedial measures after allergic reaction occurs, etc.
  • the sensitivity test management database of the present invention can also include information related to allergic reactions and the use monitoring scheme of the allergen to be tested, such as: monitoring the concentration of the allergen to be tested, monitoring related indicators, monitoring related symptoms, monitoring related physiological conditions, etc. Facts related to allergic reactions during or after drug use are obtained and analyzed.
  • the sensitivity test management database of the present invention can also include: allergy-related information and information related to allergic reaction type/allergic reaction degree grading/allergic reaction impact, wherein the allergic reaction impact can be further divided into allergic reaction impact type and impact level, and specific consequences of the impact.
  • the type of allergic reaction may include: type I (immediate type); type II (cytotoxic type); type III (immune complex type); type IV (delayed type).
  • the type of allergic reaction impact of the allergens to be tested may include: enhancement/weakening of curative effect, shortening/prolongation of onset time, increase/decrease of toxicity, increase/decrease of treatment cost, enhancement/weakening of compliance, etc.; allergic reaction impact level Can be set to ignore, minor, moderate, severe, critical, dangerous, prohibited, etc.
  • the patient information, disease information and allergen information to be tested are acquired through the information acquisition unit 12 .
  • Patient information can include: basic patient information, genetic related information, family health related information such as family medical history, medical history, allergy history, regional epidemiological history, medication history, operation history, medical device use history, learning situation, work situation, exercise situation, Family situation, living environment, hobbies, compliance, tolerance, medical insurance, and physiology/psychology/study/work/physical fitness/sleep/exercise/emotion/metabolism/vision/hearing/intelligence/attention/diet /immunity/growth and development/memory/fertility status and work and rest time and other information.
  • family health related information such as family medical history, medical history, allergy history, regional epidemiological history, medication history, operation history, medical device use history, learning situation, work situation, exercise situation, Family situation, living environment, hobbies, compliance, tolerance, medical insurance, and physiology/psychology/study/work/physical fitness/sleep/exercise/emotion/metabolism/vision/hearing/intelligence/attention/diet /immunity/growth and development
  • Disease information can include: various physiological/mental/study/work/physical fitness/sleep/exercise/emotional/metabolism/vision/hearing/intelligence/attention/appetite/immunity/growth and development/memory/fertility/genetic correlations of the patient Indicators, parameters, states or conditions of information, etc.; information obtained through inquiry, inspection, detection, test, experiment, operation, evaluation, evaluation, and observation of diseases/symptoms/indicators; and patient growth and development/birth/contraception /Assisted reproduction/Psychological needs/Learning needs/Working needs/Sports needs/Entertainment needs/Nutrition needs/calorie needs, etc.; patient's surgery/operation/examination/detection/monitoring/assessment/evaluation/analysis/prediction/physiotherapy /Heat therapy/Phototherapy/Magnet therapy/Electrotherapy/Rehabilitation/Health care/Immunotherapy/Gene therapy and other information; Information about patients' medicines/Medical devices/
  • the information of the allergen to be tested includes: the name, composition, concentration, contact method and other information of the allergen to be tested.
  • the allergen to be tested is a drug
  • its information may include: drug generic name, trade name, manufacturer, drug batch number, drug type, drug specification, drug dosage form, route of administration, site of administration, method of use, administration Dosage, medication time, medication interval, medication frequency, medication cycle and other information.
  • the sources for the information acquisition unit 12 to acquire patient information, disease information, and allergen information to be tested can be: patient-related symptoms, related indicators, feelings, states, physiological function self-reports; patient self-reports on the states and needs of study, work, life, sports, etc.
  • Medical orders issued by medical personnel patient's medical records, electronic medical records, diagnostic reports, examination results, test results, monitoring results, evaluation reports; obtained from the patient's personal information database; through inquiry, examination, detection, test, experiment, operation Information obtained by methods such as evaluation, evaluation, observation, etc.; pre-set time, season, hour, interval, cycle and other information; pre-set ways to monitor changes in various physiological and pathological indicators; patient personal information database, health Archives, family or family member health records, doctor's orders, medical records, drug records, prescriptions, electronic medical records, medical institution information systems, pharmacy/medical device store information systems, medical records, treatment records, evaluation reports, consultation records, investigation records, schedules Records/plans, diet records/plans, medication records/plans, treatment records/plans, exercise records/plans, work records/plans, study records/plans, rehabilitation records/plans, health care records/plans, inspections/checklists, operations Plans/records, health management plans, bills, clinical treatment paths, examination/test results, surgical settings/records
  • the missing information can also be provided or improved by the patient/doctor/nurse/caregiver, or the highly relevant information can be actively prompted to the patient/doctor/nurse/caregiver to observe, monitor, check, inquire, analyze, Confirm and record whether there is a relevant situation or obtain relevant indicators/performance/feeling/symptoms/physiological changes.
  • the correlation is determined by setting or through data analysis. The importance of safety, economy, suitability/comfort/compliance, etc. is graded or sorted, and the information with higher importance can be set as the information that must be completed or the next step cannot be carried out.
  • Intelligent detection/analysis equipment includes: smell, image, sound, pulse condition, X-ray film, CT, nuclear magnetic resonance, ultrasonic examination, brain wave, mass spectrometer, tongue analysis, fundus examination, gastroscope, colonoscopy, catheter, minimally invasive mirror , heart rate, blood oxygen level, blood pressure, blood sugar, blood lipid, body temperature, blood test, urine test, feces test, pulse measurement/analysis equipment, etc.
  • the database unit 11 may also store a patient personal information database, which includes relevant information of the patient for providing or supplementing the patient information.
  • the patient's personal information database includes relevant information of the patient, including: basic patient information, genetic information, and family health information such as family medical history, medical history, allergy history, regional epidemic history, medication history, surgical history, and medical device use history , study situation, work situation, sports situation, family situation, living environment, hobbies, compliance situation, tolerance situation, medical insurance situation, and physical/psychological/study/work/physical fitness/sleep/exercise/emotion/metabolism/ Information about vision/hearing/intelligence/attention/diet/immunity/growth/development/memory/fertility and work and rest time.
  • the analysis unit 13 conducts analysis according to the patient information, disease information, allergen information to be tested and the rules requiring a sensitivity test to evaluate whether a sensitivity test is required.
  • the analysis unit 13 After obtaining the patient information, disease information, and allergen information to be tested, the analysis unit 13 compares the patient information, disease information, and allergen information to be tested with the rules in the sensitivity test management database that require a sensitivity test, and analyzes Determine whether the patient needs to do the analysis results of the sensitivity test.
  • the database unit 11 can also store a sensitivity test element attribute dictionary, which is used to process information obtained from different sources, different data structures, different descriptions, and different data standards and the correlation in the database unit. Matching/comparison of information and rules.
  • Sensitivity test element attribute dictionary which contains at least one of the standard dictionary, corresponding dictionary of different names, and fuzzy matching dictionary of each element attribute related to sensitivity test, including the different names, structures, combinations and Correspondence data and so on.
  • Matching/comparison can be done by using the obtained original information to compare with the dictionaries corresponding to different names of the items in the sensitivity test element attribute dictionary, or by first converting the obtained original information into corresponding standard dictionaries and then matching them with sensitivity test management database, or use fuzzy matching between the obtained original information and the dictionaries of the sensitivity test management database, or a combination of the above methods.
  • the attribute dictionary of sensitivity test elements can be established separately, or it can be included in the sensitivity test management database.
  • the sensitivity test element attribute dictionary for matching, it can also be processed by speech recognition technology, semantic recognition technology, translation of different languages, OCR recognition technology, virtual reality technology, augmented reality technology, gesture recognition technology, etc.
  • speech recognition technology semantic recognition technology
  • translation of different languages OCR recognition technology
  • virtual reality technology virtual reality technology
  • augmented reality technology gesture recognition technology
  • the sensitivity test management system of the present invention can also provide a suitable sensitivity test plan for patients who need a sensitivity test after evaluating the results of whether a sensitivity test is required.
  • Sensitivity testing protocols may use skin testing or other methods.
  • the skin test site can be selected from the curved side of the forearm, or the skin of the upper arm or back. Specific test methods can use intradermal test, prick test or patch test.
  • the sensitivity test protocol is an appropriate protocol given based on patient information, disease information, and allergen information to be tested.
  • the rules of the sensitivity test scheme can also include the criteria for selecting the sensitivity test scheme and common schemes in various situations.
  • the relevant standards and common schemes can be manually set by experts, or can be After obtaining a large number of examples, conduct data collection, evaluate whether there are common characteristics, and use various related statistical methods, big data monitoring and other methods to establish the combination of elements with common characteristics, and can also be based on evidence-based medicine.
  • it can also include the establishment of various weights/various levels/various rankings that need to be manually set, and can also include establishment based on information reorganization/information analysis/big data analysis, It can also include those established through deep learning of artificial intelligence, or obtained through data mining and analysis, or manually set through statistical analysis of data/deep learning of artificial intelligence, or through It can be established by clinicians and pharmacists through continuous accumulation and refinement in the process of disease diagnosis and treatment, or it can be established through a combination of the above methods, and can be continuously accumulated and optimized during use.
  • the sensitivity test management system of the present invention can also obtain the data of the sensitivity test through the information acquisition unit 12, and analyze the data of the sensitivity test in combination with the rules of the sensitivity test result analysis through the analysis unit 13, and obtain the sensitivity test result. result.
  • the information acquiring unit 12 acquires the data of the sensitivity test, which may include: indicators of various sensitivity tests, skin images, position/color/area/height of changes such as skin redness and swelling, etc.
  • the analysis unit 13 analyzes the data of the sensitivity test, and can adopt a quantitative method to formulate certain standards, and obtain accurate results through precise analysis of the indicators and image data of the sensitivity test, so as to avoid relying on the doctor's personal experience. Performing the analysis results in incorrect results.
  • the image data of the sensitivity test can be identified, and at least one of the position, color, area, and height of the red and swollen part can be analyzed to obtain the result of the sensitivity test.
  • the rules for analysis of sensitivity test results may include analysis criteria for sensitivity test results.
  • the analysis standard of the sensitivity test results can be manually set by experts, or after obtaining a large number of examples, data collection can be carried out to evaluate whether there are common characteristics, and for the combination of elements with common characteristics, various relevant statistical methods,
  • the establishment of methods such as big data monitoring can also be based on methods of evidence-based medicine, or based on probability speculation based on existing data, and can also include sources such as various weights/various levels/various sorts that need to be manually set.
  • It can also include those established based on information reorganization/information analysis/big data analysis, or those established through artificial intelligence deep learning, or those obtained through data mining analysis, or those obtained through data statistical analysis/manual After intelligent deep learning, it must be manually set, or it can be established through the continuous accumulation and refinement of clinicians and pharmacists in the process of disease diagnosis and treatment, or it can be established through a combination of the above methods, and can be used during use Continuous accumulation and optimization.
  • the sensitivity test management system of the present invention can also evaluate according to the results of the sensitivity test and patient information, disease information, and allergen information to be tested, and give the evaluation results.
  • the analysis unit 13 can respectively set corresponding When evaluating the allergens to be tested, the levels/scores of the allergens to be tested can be calculated according to the corresponding levels/scores of the allergens to be tested in each analysis item and the set evaluation model of the allergens to be tested. Comprehensive level/point value. Used for test allergen assessments, including comparisons of different test allergens or test allergen regimens.
  • the allergens to be tested can be evaluated from the safety, effectiveness, economy, and suitability of the application of the allergens to be tested, and whether the application plan of the allergens to be tested is suitable for the patient can be analyzed. For example: if a patient has a severe allergic reaction to a certain drug, which may be life-threatening, the drug must not be used; and if a drug has only a mild allergic reaction, but the therapeutic effect and price of the drug are excellent, then the drug can be used Consider using.
  • the safety analysis items of the evaluation of the allergens to be tested can include: allergic risk, the severity of allergic reactions, the safety of allergy tests, etc.; the effectiveness analysis items can include: the impact on curative effect and severity, etc.; the economic analysis items It can include: treatment cost and amount, etc.; the suitability analysis items can include: the impact of compliance, etc.
  • an evaluation model of the allergens to be tested composed of the analysis results of each analysis item can be set up, so that the relationship between each analysis item and the evaluation of the allergens to be tested can be obtained.
  • the business units here can be divided into business scenarios based on various dimensions and combinations such as administration, medical institutions, departments, doctors, users, drugs, and diseases.
  • the evaluation model of the allergens to be tested can be manually set and established by experts, or after obtaining a large number of examples, data collection can be carried out to evaluate whether there are common characteristics. For the combination of elements with common characteristics, various relevant statistical methods, Establish methods such as big data monitoring.
  • the establishment of the model can be based on the method of evidence-based medicine, or based on the probability speculation of existing data, and can also include the establishment of various weights/various levels/various rankings that need to be manually set, and can also include information-based Reorganization/information analysis/big data analysis can also include those established through artificial intelligence deep learning, data mining and analysis, and data statistical analysis/artificial intelligence deep learning.
  • the parameters of the model can be manually set by experts, or obtained through data statistics/analysis, or obtained through information reorganization/big data analysis, or obtained through artificial intelligence deep learning/optimization, and can be Continuously accumulate and optimize during use.
  • the comprehensive grade/score value of the test allergen assessment can be used to give the test allergen assessment result, or to compare the test allergen or the test allergen schemes with each other.
  • a certain threshold can be set in advance.
  • Thresholds of different levels can be preset, for example: reminder level, prohibition level, warning level, suggestion level, recommendation level, report level, etc.
  • the sensitivity test management system of the present invention can also optimize and adjust the application plan of the patient's original allergen to be tested according to the evaluation result of the allergen to be tested.
  • the method for optimizing and adjusting the specific application plan may include: adjusting the use plan of the relevant test allergen, adjusting the relevant test allergen, carrying out the use monitoring of the relevant test allergen or other treatment methods, etc. at least one.
  • Adjustment of the relevant drug usage plan includes: adjustment of the relevant drug administration time plan, adjustment of the relevant drug use method plan, etc. Specifically, it includes: at least one of adjusting the frequency of administration, adjusting the time interval between medications, adjusting the route of administration, adjusting the site of administration, and adjusting the method of use, etc., or a combination of two or more.
  • the above-mentioned adjustment of the administration time of relevant drugs refers to reducing or eliminating the influence of allergic reactions by adjusting the administration frequency or time of administration of the drugs.
  • the specific adjustment method is: according to the relationship between the impact of drug allergic reaction and the time interval of drug use, as well as the reasonable drug use time range of each drug that may have a certain risk of allergic reaction, it can be obtained that the relevant drug is in line with the reasonable drug use time range.
  • the drug administration time plan that minimizes the impact of allergic reactions is the optimal drug use time plan.
  • the drug use time optimization scheme may be one or a collection of multiple time schemes.
  • the allergic reaction can be eliminated by adjusting the administration time of A or B, prolonging the interval between the two drugs, and avoiding the generation of product C. Impact.
  • Adjusting the usage method of relevant drugs mentioned above refers to reducing or eliminating the impact of allergic reactions by adjusting the route of administration, the site of administration, and the method of use. Comprehensively analyze the range of possible adjustments of relevant drug usage methods through pharmacokinetics, disease characteristics, user compliance and other factors. For example, some external medicines will cause allergic reactions when used on the face, but there is no allergic phenomenon when used on other parts of the body. You can reduce or eliminate the impact of allergic reactions by adjusting the administration site and avoiding use on sensitive skin parts.
  • Adjustment of relevant drugs includes at least one of the following: reducing drugs, increasing drugs, changing drugs, etc. on the basis of the original drug regimen. Specifically, it includes: excluding drugs that may have a certain risk of allergic reaction from the drug regimen, replacing drugs that may have a certain risk of allergic reaction with other drugs that have the same clinical effect but have a lower risk of allergic reaction. On this basis, new drugs are added to reduce the risk of original allergic reactions.
  • the reduction of drugs mentioned above refers to reducing or eliminating the impact of allergic reactions by stopping one or several drugs in the original drug regimen.
  • the choice of drug discontinuation may include whether the drug is the preferred/first-line treatment for a certain indication, whether the drug is used for a long time, etc.
  • patients with type 2 diabetes mellitus combined with metformin and sulfonylurea hypoglycemic drugs assuming that the blood sugar control of the patient has reached the target with metformin alone before adding sulfonylureas, and the patient has a history of allergy to sulfonylureas, it can be stopped by stopping the sulfonylureas. Eliminates the risk of allergic reactions.
  • the above-mentioned replacement of drugs refers to reducing or eliminating the impact of allergic reactions by replacing one or several drugs in the original drug regimen.
  • Changing medicines includes changing dosage forms, changing specifications, changing manufacturers, changing drug names, etc.
  • factors can include whether the drug is the preferred/first-line treatment for a certain indication, whether the drug has an alternative, whether the current business unit has an alternative to the drug, whether the drug is long-term Medication, etc.
  • patients with type 2 diabetes who have a history of allergy to sulfonamides may experience cross-allergies when taking sulfonylureas.
  • the sulfonylureas can be replaced by other oral hypoglycemic agents such as biguanides and glucosidase inhibitors.
  • Adding drugs as mentioned above refers to reducing or eliminating the impact of allergic reactions by adding new drugs on the basis of the original drug regimen.
  • the incidence of hypersensitivity reactions among users receiving paclitaxel injection is as high as 30% to 41%.
  • Pretreatment with glucocorticoids plus H1 and H2 receptor antagonists can be performed before infusion of paclitaxel injection to prevent hypersensitivity. reaction occurs.
  • the above-mentioned relevant medication monitoring scheme includes at least one of: monitoring the blood drug concentration of relevant drugs, monitoring related indicators, monitoring related symptoms, and monitoring related physiological conditions. For example, if a patient may be allergic to a certain drug, but there is no replacement plan, the relevant indicators and symptoms of the patient can be closely monitored. Once allergic indications appear, the drug should be stopped immediately.
  • the above-mentioned other treatment methods include: at least one of surgery, physical therapy, traditional Chinese medicine therapy, psychotherapy, rehabilitation therapy, and comprehensive health management.
  • the method of optimizing the drug regimen can also be a combination of the above methods, that is, adjusting the time regimen of relevant drug administration, adjusting the regimen of relevant drug usage, reducing drugs, increasing drugs, changing drugs, carrying out relevant drug monitoring, using other treatment methods, etc. Two or more of them are used at the same time.
  • whether a sensitivity test is required, the results of the sensitivity test, and the evaluation results of the allergens to be tested given by the sensitivity test management system can be used to assist in reminding, warning, restricting, prohibiting, assisting, and guiding patients/ Physician/Nurse/Caregiver for treatment. It can also be used for patient/doctor/nurse/caregiver and referral/management/guidance/counseling post or secondary referral/management/guidance/counseling center discussion and data basis for advanced post reply/auto-reply. It can also be used as a basis for professional level evaluation/professional normative evaluation/performance evaluation/performance appraisal of doctors/nurses/caregivers and other personnel afterwards.
  • It can also be used as a basis for sales or refusal of sales by unmanned vending machines/e-commerce/pharmacies/medical institutions. It can also be connected with various information systems/information platforms/various unmanned vending machines/smart wearable devices/smart home devices/smart medical devices/medical devices/remote control medical devices, as related operations or processes triggered by systems or related devices Configurable control items, such as vending, smart reminder, smart start, smart shutdown, etc. It can also be used as a medical insurance management agency/medical insurance company/health administrative department/credit evaluation agency/grade review agency/judicial agency to evaluate, assess, supervise, enforce, manage, and refer to medical institutions/pharmacies/medical equipment retail stores.
  • the data basis for sales can also be used for data when medical insurance management agencies/medical insurance companies/price management departments/health administrative departments/medical institutions formulate surgery-related policies/regulations/payment scope/payment ratio/payment amount/use scope, etc.
  • the analysis results of each analysis item are fed back to different departments and different positions, and the processing authority and process of each department and position are set.
  • various corresponding analysis result reports can also be generated according to management requirements.
  • the application of sensitivity test management results can be in the mode of prior recommendation, mid-event review, or post-event evaluation.
  • the normative evaluation report issued is provided to the medical administration management personnel, medical insurance institutions, medical insurance management personnel, and circulation field management personnel to prompt various violations and illegal acts that may exist, in order to further standardize diagnosis and treatment process support.
  • various analysis results, assessments, reports and other output information of the sensitivity test management system can be manually completed by professionals according to the sensitivity test management database and various data, or manually completed with the support of the system, It can also be completed automatically by the system, by artificial intelligence, or by a combination of system/artificial intelligence and manual completion.
  • the form of application/output of relevant sensitivity test management and analysis results can be reminders, notifications, reports, reports, system authority restrictions, system process restrictions, control of related systems/equipment/files/authorities, etc.; it can also be the provision of relevant interfaces It can also be implemented by connecting with other management systems; it can also be an application that provides analysis results and the user manually implements the relevant analysis results.
  • the identification, confirmation, login, and electronic signature of patients, medical personnel, and related roles in the sensitivity test management system, as well as the storage, transmission, and application of personal information, medical information, and various analysis results can be done through Various methods are used for encryption to prevent related identities/permissions from being stolen or information leaked.
  • the encryption algorithms include symmetric encryption algorithms and/or asymmetric encryption algorithms, such as: encryption algorithms for large integer decomposition problems, encryption algorithms for discrete logarithm problems, and elliptic curve encryption algorithms, such as blockchain technology, etc.
  • the encryption hardware can Using keys, dongles, encrypted hard disks, etc., can also be combined with user equipment hardware, network addresses, etc. for encryption, and the above methods can also be combined for encryption.
  • the data transmission mode of the sensitivity test management system can be data line mode, wired network, wireless transmission mode, radio frequency identification mode, magnetic card reading and writing mode, mobile hard disk mode, NFC mode, bar code mode, two-dimensional code mode wait.
  • Wireless transmission methods include: infrared, bluetooth, wifi, microwave, visible light wave, telecommunications wireless network, ultrasonic/sound wave, radio and other methods.
  • the susceptibility test management system can be used as a stand-alone machine, or can be used by users with access-type external hardware such as mobile hard disks, boxes, cards, etc., or can be installed on local servers to support local users, or can be installed on
  • the private cloud server supports the use of private cloud users, and can also be installed on the Internet to provide services to Internet users.
  • Fig. 2 is a method flowchart of a sensitivity test management method of the present invention.
  • the sensitivity test management method of the present invention includes:
  • Step 1 establishing a sensitivity test management database, the sensitivity test management database includes rules that require sensitivity tests;
  • Step 2 obtaining patient information, disease information and allergen information to be tested
  • Step 3 Analyze according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.
  • the sensitivity test management method of the present invention may also include:
  • Step 4 obtaining the data of the sensitivity test and analyzing the data of the sensitivity test to obtain the result of the sensitivity test.
  • the sensitivity test management method of the present invention may also include:
  • Step 5 Evaluate the allergen to be tested according to the results of the sensitivity test, patient information, disease information, and allergen to be tested, and give the evaluation result.
  • the sensitive test management method of the present invention corresponds to the technical features of the sensitive test management system of the present invention one by one, and reference may be made to the description of the aforementioned sensitive test management system, which will not be repeated here.
  • a sensitivity test management system and method of the present invention includes: a database unit, an information acquisition unit and an analysis unit.
  • Sensitivity test management methods include: establishing a sensitivity test management database, obtaining patient information, disease information, and test allergen information, and performing analysis based on patient information, disease information, test allergen information, and rules requiring sensitivity tests, Assess the need for sensitivity testing.
  • sensitivity test management is carried out from various aspects such as rules for sensitivity tests, quantitative analysis of test results, and analysis of allergens to be tested according to test results, which is beneficial High-quality management of sensitivity tests plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.

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Abstract

A sensitivity test management system and method. The sensitivity test management system comprises: a database unit (11), an information acquisition unit (12), and an analysis unit (13). The sensitivity test management method comprises: establishing a sensitivity test management database (S1); acquiring patient information, disease information, and information of a substance to be tested for allergens (S2); and according to the patient information, the disease information, the information of the substance and a rule requiring a sensitivity test, performing an analysis to evaluate whether a sensitivity test is required (S3). By means of the system and the method, sensitivity test management is carried out from multiple aspects such as the rule requiring the sensitivity test, the quantitative analysis of test results and the analysis of the substance according to the test results, such that the system and method play an enormous role in promoting the high-quality management of sensitivity tests, improving medical quality, preventing anaphylactic reactions, guaranteeing of safety of patients and the like.

Description

一种敏感性试验管理系统及方法A sensitivity test management system and method 技术领域technical field
本发明涉及智能化医疗信息处理的技术领域,特别是涉及一种敏感性试验管理系统及方法。The invention relates to the technical field of intelligent medical information processing, in particular to a sensitivity test management system and method.
背景技术Background technique
随着科技的不断发展,人们生活水平不断提高,对于医疗质量的需求也不断增加。在人们接受医疗服务的过程中,过敏严重影响医疗质量,甚至危及生命。由于医学科学的局限性、疾病自身特点、医院管理因素、医生业务水平、药品和医疗器械、患者自身实际情况等因素,使得医疗过程中存在一定几率的过敏风险。With the continuous development of science and technology, people's living standards are constantly improving, and the demand for medical quality is also increasing. In the process of people receiving medical services, allergies seriously affect the quality of medical care, and even endanger their lives. Due to the limitations of medical science, the characteristics of the disease itself, hospital management factors, doctors' professional level, drugs and medical devices, and the actual situation of patients themselves, there is a certain probability of allergic risk in the medical process.
现有的敏感性试验通常是在医生用药前进行,为了防止过敏反应的发生,特别是严重过敏反应的发生,规定一些容易发生过敏反应的药物在使用前需要做皮肤敏感试验,皮试阴性的药物可以给病人使用,皮试阳性的则禁止使用。现有敏感性试验通常只针对特定药物,而较少考虑患者与疾病情况,对于实验结果也主要是根据经验进行判断,缺乏量化标准。同时,敏感试验的假阳性会影响准确的药物选择,可能会导致用药风险、过度医疗等问题,甚至可能延误患者的及时救治。The existing sensitivity test is usually carried out before the doctor takes the medicine. In order to prevent the occurrence of allergic reactions, especially the occurrence of severe allergic reactions, it is stipulated that some drugs that are prone to allergic reactions need to be tested for skin sensitivity before use. If the skin test is negative Drugs can be given to patients, but are prohibited if the skin test is positive. Existing sensitivity tests are usually only for specific drugs, and less consideration is given to patients and disease conditions, and the experimental results are mainly judged based on experience, lacking quantitative standards. At the same time, false positives in sensitive tests will affect accurate drug selection, which may lead to medication risks, over-medication and other problems, and may even delay the timely treatment of patients.
因此,应用信息化技术,结合医学、药学专业数据和业务,建立一套实用、全面的敏感性试验管理系统及方法,从是否需要做敏感性试验的条件、实验结果的量化分析、以及根据实验结果进行用药分析等多方面进行敏感性试验管理,有利于高质量管理敏感性试 验,提高医疗质量、防止过敏反应、保障患者安全等方面发挥巨大的作用。Therefore, apply information technology, combine medical and pharmacy professional data and business, establish a set of practical and comprehensive sensitivity test management system and method, from whether sensitivity test needs to be done, quantitative analysis of test results, and based on test Results Management of sensitivity tests in many aspects, such as medication analysis, is conducive to high-quality management of sensitivity tests, and plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.
发明内容Contents of the invention
本发明的主要目的是:针对现有的敏感性试验管理精细化不够的现状,提供一种敏感性试验管理系统及方法,从是否需要做敏感性试验的评估、实验结果的量化分析、以及根据实验结果进行用药分析等多方面进行敏感性试验管理,有利于高质量管理敏感性试验,提高医疗质量、防止过敏反应、保障患者安全等方面发挥巨大的作用。The main purpose of the present invention is to provide a sensitivity test management system and method for the current situation that the existing sensitivity test management is not refined enough, from the assessment of whether the sensitivity test is needed, the quantitative analysis of the experimental results, and the basis Management of sensitivity tests in various aspects, such as drug analysis of experimental results, is conducive to high-quality management of sensitivity tests, and plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.
为实现上述目的,本发明提供了一种敏感性试验管理系统,所述系统包括:To achieve the above object, the present invention provides a sensitivity test management system, said system comprising:
数据库单元,用于存储敏感性试验管理数据库,所述敏感性试验管理数据库包括需要做敏感性试验的规则;The database unit is used to store a sensitivity test management database, and the sensitivity test management database includes rules that require sensitivity tests;
信息获取单元,用于获取患者信息、疾病信息和待测过敏物信息,所述待测过敏物包括:药物、饮食、医疗器械、光照、化妆品、日用品、空气、衣物中的至少一种;An information acquisition unit, configured to acquire patient information, disease information, and information on allergens to be tested, the allergens to be tested include: at least one of medicine, diet, medical equipment, light, cosmetics, daily necessities, air, and clothing;
分析单元,用于根据患者信息、疾病信息、待测过敏物信息和需要做敏感性试验的规则进行分析,评估是否需要做敏感性试验。The analysis unit is configured to perform analysis according to the patient information, disease information, allergen information to be tested and the rules requiring a sensitivity test to evaluate whether a sensitivity test is required.
如上所述的一种敏感性试验管理系统,所述敏感性试验管理数据库包括敏感性试验方案的规则,所述敏感性试验管理系统对于需 要做敏感性试验的患者,给出适合的敏感性试验方案。A sensitivity test management system as described above, the sensitivity test management database includes the rules of the sensitivity test scheme, and the sensitivity test management system provides a suitable sensitivity test for patients who need a sensitivity test plan.
如上所述的一种敏感性试验管理系统,所述数据库单元还存储有患者个人信息数据库,所述患者个人信息数据库中包括患者的相关信息,用于提供或补充患者信息。According to the sensitivity test management system described above, the database unit further stores a patient personal information database, and the patient personal information database includes relevant information of the patient for providing or supplementing the patient information.
如上所述的一种敏感性试验管理系统,所述敏感性试验管理数据库包括敏感性试验结果分析的规则,所述敏感性试验管理系统通过所述信息获取单元获取敏感性试验的数据,并通过所述分析单元对敏感性试验的数据进行分析,得到敏感性试验的结果。A sensitivity test management system as described above, the sensitivity test management database includes rules for analysis of sensitivity test results, the sensitivity test management system obtains the data of the sensitivity test through the information acquisition unit, and The analysis unit analyzes the data of the sensitivity test to obtain the result of the sensitivity test.
如上所述的一种敏感性试验管理系统,所述分析单元对敏感性试验的影像数据进行识别,通过红肿部位的位置、颜色、面积、高度中的至少一项数据,分析得出敏感性试验的结果。A sensitivity test management system as described above, the analysis unit identifies the image data of the sensitivity test, and analyzes at least one of the data of the position, color, area, and height of the red and swollen part to obtain the sensitivity test the result of.
如上所述的一种敏感性试验管理系统,所述敏感性试验管理系统根据敏感性试验的结果和患者信息、疾病信息、待测过敏物信息进行评估,给出评估结果。According to the sensitivity test management system as described above, the sensitivity test management system evaluates according to the results of the sensitivity test and patient information, disease information, and allergen information to be tested, and gives the evaluation results.
如上所述的一种敏感性试验管理系统,所述分析单元根据在不同的患者信息和疾病信息的条件下,待测过敏物在包括安全性、有效性、经济性、适宜性中的至少一项分析项目的不同分析结果,分别设定对应的级别/分值,在进行待测过敏物评估时,能够根据待测过敏物在各分析项目所对应的级别/分值以及设置的待测过敏物评估模型,计算出不同待测过敏物的综合级别/分值。According to a sensitivity test management system as described above, the analysis unit is based on at least one of safety, effectiveness, economy, and suitability of the allergen to be tested under different conditions of patient information and disease information. For different analysis results of each analysis item, set the corresponding grades/scores respectively. The substance evaluation model is used to calculate the comprehensive grade/score of different allergens to be tested.
如上所述的一种敏感性试验管理系统,所述敏感性试验管理系统还根据待测过敏物评估结果对患者的原应用方案进行优化与调 整。应用方案优化与调整的方法可以包括:调整相关待测过敏物使用方案、调整相关待测过敏物、开展相关待测过敏物使用监测或其他治疗方法等至少一种。According to the above-mentioned sensitivity test management system, the sensitivity test management system also optimizes and adjusts the patient's original application plan according to the evaluation results of the allergens to be tested. The method of optimizing and adjusting the application plan may include: adjusting the use plan of the relevant test allergen, adjusting the relevant test allergen, carrying out the use monitoring of the relevant test allergen or other treatment methods, etc. at least one.
本发明还提供一种敏感性试验管理方法,所述方法包括:The present invention also provides a sensitivity test management method, the method comprising:
步骤1,建立敏感性试验管理数据库,所述敏感性试验管理数据库包括需要做敏感性试验的规则;Step 1, establishing a sensitivity test management database, the sensitivity test management database includes rules that require sensitivity tests;
步骤2,获取患者信息、疾病信息和待测过敏物信息;Step 2, obtaining patient information, disease information and allergen information to be tested;
步骤3,根据患者信息、疾病信息、待测过敏物信息和需要做敏感性试验的规则进行分析,评估是否需要做敏感性试验。Step 3: Analyze according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.
本发明的一种敏感性试验管理系统及方法,敏感性试验管理系统包括:数据库单元、信息获取单元和分析单元。敏感性试验管理方法包括:建立敏感性试验管理数据库,获取患者信息、疾病信息和待测过敏物信息,根据患者信息、疾病信息、待测过敏物信息和需要做敏感性试验的规则进行分析,评估是否需要做敏感性试验。通过本发明的一种敏感性试验管理系统及方法,从需要做敏感性试验的规则、试验结果的量化分析、以及根据试验结果进行待测过敏物分析等多方面进行敏感性试验管理,有利于高质量管理敏感性试验,提高医疗质量、防止过敏反应、保障患者安全等方面发挥巨大的作用。A sensitivity test management system and method of the present invention, the sensitivity test management system includes: a database unit, an information acquisition unit and an analysis unit. Sensitivity test management methods include: establishing a sensitivity test management database, obtaining patient information, disease information, and test allergen information, and performing analysis based on patient information, disease information, test allergen information, and rules requiring sensitivity tests, Assess the need for sensitivity testing. Through a sensitivity test management system and method of the present invention, sensitivity test management is carried out from various aspects such as rules for sensitivity tests, quantitative analysis of test results, and analysis of allergens to be tested according to test results, which is beneficial High-quality management of sensitivity tests plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.
附图说明Description of drawings
图1为本发明一种敏感性试验管理系统的框图。Fig. 1 is a block diagram of a susceptibility test management system of the present invention.
图2为本发明一种敏感性试验管理方法的方法流程图。Fig. 2 is a flow chart of a sensitivity test management method of the present invention.
具体实施方式Detailed ways
为进一步阐述本发明达成预定目的所采取的技术手段及功效,以下结合附图及实施例,对本发明的具体实施方式,详细说明如下。In order to further explain the technical means and effects adopted by the present invention to achieve the intended purpose, the specific implementation of the present invention will be described in detail below in conjunction with the accompanying drawings and examples.
在本发明中,敏感性试验包括皮肤(或皮内)敏感试验,还可以包括其他的敏感性试验。某些药物在临床使用过程中容易发生过敏反应,如青霉素、链霉素、细胞色素C等,常见的过敏反应包括皮疹、荨麻疹、皮炎、发热、血管神经性水肿、哮喘、过敏性休克等,其中以过敏性休克最为严重,甚至可导致死亡。为了防止过敏反应的发生,特别是严重过敏反应的发生,规定一些容易发生过敏反应的药物在使用前需要做皮肤敏感试验,皮试阴性的药物可以给病人使用,皮试阳性的则禁止使用。待测过敏物可以包括:药物、饮食、医疗器械、光照、化妆品、日用品、空气、衣物等。In the present invention, the sensitivity test includes skin (or intradermal) sensitivity test, and may also include other sensitivity tests. Some drugs are prone to allergic reactions during clinical use, such as penicillin, streptomycin, cytochrome C, etc. Common allergic reactions include rash, urticaria, dermatitis, fever, angioedema, asthma, anaphylactic shock, etc. Among them, anaphylactic shock is the most serious and can even lead to death. In order to prevent the occurrence of allergic reactions, especially the occurrence of severe allergic reactions, it is stipulated that some drugs that are prone to allergic reactions need to be tested for skin sensitivity before use. Drugs with negative skin tests can be given to patients, and those with positive skin tests are prohibited. The allergens to be tested may include: drugs, diet, medical equipment, light, cosmetics, daily necessities, air, clothing, etc.
在本发明中,患者指敏感性试验管理系统分析的对象,可以包括:生病者、体检者、孕妇、儿童、特种岗位人员、受试者等,也可以是需要测试过敏情况的其他人群。In the present invention, patients refer to the objects analyzed by the sensitivity test management system, which may include: sick people, medical examiners, pregnant women, children, personnel in special positions, subjects, etc., and may also be other groups of people who need to be tested for allergies.
本发明第一实施例参阅图1。图1为本发明一种敏感性试验管理系统的框图。如图所示,本发明的一种敏感性试验管理系统包括:Refer to FIG. 1 for the first embodiment of the present invention. Fig. 1 is a block diagram of a susceptibility test management system of the present invention. As shown in the figure, a sensitivity test management system of the present invention includes:
数据库单元11,用于存储敏感性试验管理数据库,所述敏感性 试验管理数据库包括需要做敏感性试验的规则; Database unit 11, is used for storing sensitivity test management database, and described sensitivity test management database includes the rule that needs to do sensitivity test;
信息获取单元12,用于获取患者信息、疾病信息和待测过敏物信息;An information acquisition unit 12, configured to acquire patient information, disease information and allergen information to be tested;
分析单元13,用于根据患者信息、疾病信息、待测过敏物信息和需要做敏感性试验的规则进行分析,评估是否需要做敏感性试验。The analysis unit 13 is configured to perform analysis according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.
首先,需要建立敏感性试验管理数据库。First, a sensitivity test management database needs to be established.
在本发明中,敏感性试验管理数据库可以包括:需要做敏感性试验的规则,还可以包括敏感性试验方案的规则和敏感性试验结果分析的规则。具体可以包括各种相关要素属性及其各要素属性的值/范围/计算方法/来源/限制条件/排除条件,各种/各组/各类要素属性之间的相互关系/相互影响/相互转化/规则/计算方法。In the present invention, the sensitivity test management database may include: rules requiring sensitivity tests, and may also include rules for sensitivity test schemes and rules for analysis of sensitivity test results. Specifically, it can include various related element attributes and their values/ranges/calculation methods/sources/restrictions/exclusions, and the interrelationships/interactions/transformations between various/groups/various element attributes /rule/calculation method.
需要做敏感性试验的规则是通过患者信息、疾病信息和待测过敏物信息综合判断,符合一定的规则则需要做敏感性试验。例如:有些药物是按规定必须做皮试的药物;还有些药物是在特定情况下才需要做皮试的药物,如:胸腺肽注射液过敏体质者需做皮试。由于过敏反应的发生与抗生素内在的致敏原及患者自身的过敏性体质密切相关,因此,需要综合考虑患者信息、疾病信息和待测过敏物信息,来确定是否需要做敏感性试验,而不是单纯通过使用的待测过敏物来判断是否需要做敏感性试验。The rule that requires a sensitivity test is based on a comprehensive judgment of patient information, disease information, and allergen information to be tested. If certain rules are met, a sensitivity test is required. For example: Some drugs require skin tests according to regulations; some drugs require skin tests only under specific circumstances, such as: those who are allergic to thymosin injection need to do skin tests. Since the occurrence of allergic reactions is closely related to the internal allergens of antibiotics and the patient's own allergic constitution, it is necessary to comprehensively consider the information of the patient, the disease, and the allergen to be tested to determine whether a sensitivity test is required, rather than Simply by using the allergens to be tested to determine whether a sensitivity test is required.
本发明的敏感性试验管理数据库及其内容是基于各种诊疗标准、诊疗规范、指南、行业规范、教材、临床治疗路径、药物说明 书、医疗设备使用/操作说明书、医疗器械使用说明书、手术操作规范、检查/检验规范、处方集、药典、专家共识、专家经验、医联体/医院/科室内部的会议纪要及共识、论文、专著、发明、科学推论、实验报告、试验报告、数据分析报告、测试报告、检测报告、审批文件、相关法规、相关指导意见、相关政策、相关制度、相关目录、相关文献资料、相关价格规定、相关价格目录、相关招标结果、相关物价政策、相关保险支付条款、相关保险支付协议、相关招标结果、相关采购目录、相关医生/护士/检验师/药师/护理人员/患者/售货员的评价/检查结果/监测报告/安全报告、其他文献资料、其他具有专业性/权威性的研究结果,还可以基于循证医学的方法,或基于现有数据的概率推测,还可以包括需要人工设定的各种权重/各种等级/各种排序等来源建立的数据库,也可以包括基于信息重整/信息分析/大数据分析建立的数据库,也可以包括通过人工智能深度学习建立的数据库,也可以包括通过数据挖据分析后得出的数据库,也可以包括通过数据统计分析/人工智能深度学习后得经过人工设定出的规则和指标,也可以是在通过临床医生、药师在疾病治疗过程中不断积累和细化的相关信息和规则。敏感性试验管理数据库也可以是通过上述方法组合建立的数据库。数据库可以是按版本更新,也可以是根据实际数据实时更新。敏感性试验管理数据库可以是关系型数据库,也可以是非关系型数据库;可以是表数据库,也可以是图数据库,还可以是知识图谱数据库;相关数据可以是结构化数据,也可以是非结构化数据。The sensitivity test management database and its contents of the present invention are based on various diagnosis and treatment standards, diagnosis and treatment norms, guidelines, industry norms, teaching materials, clinical treatment paths, drug instructions, medical equipment use/operation instructions, medical device instruction manuals, surgical operation specifications , inspection/inspection specifications, formulary, pharmacopoeia, expert consensus, expert experience, meeting minutes and consensus within the medical consortium/hospital/department, papers, monographs, inventions, scientific inferences, experimental reports, experimental reports, data analysis reports, Test reports, test reports, approval documents, relevant regulations, relevant guidance, relevant policies, relevant systems, relevant catalogs, relevant literature, relevant price regulations, relevant price catalogs, relevant bidding results, relevant price policies, relevant insurance payment terms, Relevant insurance payment agreements, relevant bidding results, relevant procurement catalogs, relevant doctors/nurses/examiners/pharmacists/nursing staff/patients/salespersons’ evaluations/test results/monitoring reports/safety reports, other literature, other professional/ Authoritative research results can also be based on methods of evidence-based medicine, or based on probabilistic speculation based on existing data, and can also include databases established from sources such as various weights/grades/ranks that need to be manually set, or It can include databases established based on information reorganization/information analysis/big data analysis, databases established through artificial intelligence deep learning, databases obtained through data mining analysis, and data statistical analysis After the deep learning of artificial intelligence, the rules and indicators set manually, or the relevant information and rules accumulated and refined by clinicians and pharmacists in the process of disease treatment can also be used. The sensitivity test management database can also be a database established by combining the above methods. The database can be updated by version, or it can be updated in real time based on actual data. The sensitivity test management database can be a relational database or a non-relational database; it can be a table database, a graph database, or a knowledge map database; relevant data can be structured data or unstructured data .
敏感性试验管理数据库中的需要做敏感性试验的规则以及敏感性试验方案的规则和敏感性试验结果分析的规则所涉及的要素可以包括:待测过敏物的各种使用条件/要求/属性/数值,如药物的厂 家、规格、剂型、日频率、时间间隔、次/日用量、次/日极量、使用方法、敏感性、给药途径、给药部位等。还包括:患者的基本信息、人群信息、遗传相关信息、疾病信息、病史信息、用药史信息、医疗器械使用史信息、接触史、暴露史、操作项目、症状、指标、身体位置、操作对象、操作方法、操作目标、生理发育信息、婚育信息、生理状况、心理/智力状况、生活/工作/学习/运动/娱乐信息、环境信息、药物/医疗器械/保健品/化妆品使用相关信息、医疗保险相关信息、医疗费用支付能力/意愿、医疗机构信息、医疗人员信息、药物所需医疗器械/耗材/设备/仪器/药物/植入物、药物的费用、照护、风险评估、分期、阶段、麻醉、呼吸、止血、感染预防、疼痛、急救措施、指标控制、准备和要求、训练、适应症/指征、禁忌症、相关防护和急救、营养支持、医生级别及权限、辅助软件、影像等各项要素信息。In the sensitivity test management database, the rules related to the need for sensitivity test, the rules of the sensitivity test program and the rules of sensitivity test result analysis may include: various use conditions/requirements/attributes/ Numerical values, such as drug manufacturer, specification, dosage form, daily frequency, time interval, time/daily dosage, time/day maximum dosage, method of use, sensitivity, route of administration, site of administration, etc. Also includes: basic patient information, population information, genetic information, disease information, medical history information, medication history information, medical device use history information, contact history, exposure history, operation items, symptoms, indicators, body position, operation objects, Operation methods, operation objectives, physiological development information, marriage and childbirth information, physiological conditions, psychological/intellectual conditions, life/work/study/sports/entertainment information, environmental information, information related to the use of drugs/medical devices/health products/cosmetics, medical treatment Insurance-related information, ability/willingness to pay for medical expenses, medical institution information, medical personnel information, medical devices/consumables/equipment/instruments/drugs/implants required for drugs, drug costs, care, risk assessment, stages, stages, Anesthesia, respiration, hemostasis, infection prevention, pain, first aid measures, index control, preparation and requirements, training, indications/indications, contraindications, related protection and first aid, nutritional support, doctor level and authority, auxiliary software, imaging, etc. Information about various elements.
在本发明中,人群信息可以包括特定年龄、性别、发育状况、婚姻状况、生育状况、工作状况、学习状况、运动状况、生活状况、生理状况、心理状况、遗传学状况、身体状况、免疫状况等特定人群信息。遗传相关信息包括:遗传信息、遗传信息变异/改变信息、遗传缺陷信息、遗传病史、家族病史等信息。疾病信息包括:疾病、诊断、症状、症型、症候、指标、脉象、舌诊等信息。病史信息包括病史、手术史、放疗史、化疗史、心理治疗史、理疗史、免疫治疗史、基因治疗史等等信息。用药史信息包括:用药史、药物疗效、药物不良反应、药物过敏史、药物耐受情况等等信息。医疗器械使用史信息包括:医疗器械使用史、医疗器械使用疗效、医疗器械使用不良反应、医疗器械耐受情况等等信息。操作项目包括手术、检查、检验、测试、检测、操作、保健、康复、心理治疗、 放疗、化疗、理疗、热疗、光疗、磁疗、电疗、冷疗、电磁疗、声疗、免疫疗法、基因治疗、减肥、健身、整形、美容等项目。生理发育信息包括:生长发育情况、生理阶段、生育能力等信息。婚育信息包括婚史、生育史、性生活等信息。生理状况包括:体能、营养状况、听力、视力、味觉、嗅觉、触觉、呼吸、运动协调、消化、吸收、排泄、性功能等状况和相关能力的水平。心理/智力状况包括:心理疾病、情绪、感受、智力、注意力、记忆力、感知力、沟通能力、表达能力等等。生活/工作/学习/运动/娱乐信息包括:饮食、作息、睡眠、工作、学习、娱乐、运动等相关信息。环境信息包括:微生物分布情况、接触人群情况、温度、湿度、气压、季节、海拔、空气质量、空气扩散条件、地形、地貌、含氧量、光照、紫外线、辐射、电磁波、噪音、流行病、植物等信息。医疗保险相关信息包括医疗福利、医疗保险、商业保险等。医疗机构信息包括医疗机构级别、专科、属性、地区,科室等信息。医疗人员信息包括:年龄、性别、职务、职称、专业资格、专业培训、防护措施等信息。植入物包括:移植物、培养物、基因载体、植入芯片、植入设备/装置等。营养支持包括:水分、热量、蛋白质、微量元素、糖、盐、脂肪、碳水化合物、矿物质、氨基酸、维生素的检测、含量标准、补充剂量等。In the present invention, group information may include specific age, gender, developmental status, marital status, childbearing status, working status, learning status, exercise status, living status, physiological status, psychological status, genetic status, physical status, immune status and other specific population information. Genetic related information includes: genetic information, genetic information variation/change information, genetic defect information, genetic medical history, family medical history and other information. Disease information includes: disease, diagnosis, symptom, symptom type, symptom, index, pulse condition, tongue diagnosis and other information. Medical history information includes medical history, surgical history, radiotherapy history, chemotherapy history, psychotherapy history, physical therapy history, immunotherapy history, gene therapy history, and other information. Medication history information includes: medication history, drug efficacy, adverse drug reactions, drug allergy history, drug tolerance, and other information. Medical device use history information includes: medical device use history, medical device efficacy, medical device adverse reactions, medical device tolerance, etc. Operation items include surgery, inspection, inspection, test, detection, operation, health care, rehabilitation, psychological treatment, radiotherapy, chemotherapy, physical therapy, hyperthermia, phototherapy, magnetic therapy, electrotherapy, cold therapy, electromagnetic therapy, sound therapy, immunotherapy, Gene therapy, weight loss, fitness, plastic surgery, beauty and other projects. Physiological development information includes: growth and development, physiological stage, fertility and other information. Marriage information includes marriage history, birth history, sex life and other information. Physiological conditions include: physical fitness, nutritional status, hearing, vision, taste, smell, touch, breathing, motor coordination, digestion, absorption, excretion, sexual function, etc. and the level of related abilities. Mental/intellectual conditions include: mental illness, emotions, feelings, intelligence, attention, memory, perception, communication skills, expressive skills, etc. Life/work/study/sports/entertainment information includes: diet, work and rest, sleep, work, study, entertainment, sports and other related information. Environmental information includes: microbial distribution, contact population, temperature, humidity, air pressure, season, altitude, air quality, air diffusion conditions, terrain, landform, oxygen content, light, ultraviolet rays, radiation, electromagnetic waves, noise, epidemics, plant information. Medical insurance related information includes medical benefits, medical insurance, commercial insurance, etc. Medical institution information includes medical institution level, specialties, attributes, regions, departments and other information. Medical personnel information includes: age, gender, position, professional title, professional qualifications, professional training, protective measures and other information. Implants include: grafts, cultures, gene carriers, implanted chips, implanted equipment/devices, etc. Nutritional support includes: water, calories, protein, trace elements, sugar, salt, fat, carbohydrates, minerals, amino acids, vitamin testing, content standards, supplementary dosage, etc.
敏感性试验管理数据库中的需要做敏感性试验的规则,以及敏感性试验方案的规则和敏感性试验结果分析的规则,可以是以单个待测过敏物或待测过敏物分类为对象建立,也可以包括以各需要联合使用的待测过敏物组为对象来建立的部分。The rules in the sensitivity test management database that require sensitivity tests, the rules of the sensitivity test program and the rules of the analysis of sensitivity test results can be established based on a single allergen to be tested or a classification of allergens to be tested, or It may include sections established for each test allergen group to be used in combination.
在本发明中,敏感性试验方案的规则是根据不同的患者信息、 疾病信息、待测过敏物信息,采用适合的敏感性试验方案的规则。敏感性试验管理系统对于需要做敏感性试验的患者,根据患者信息、疾病信息、待测过敏物信息,以及敏感性试验方案的规则给出适合的敏感性试验方案。In the present invention, the rules of the sensitivity test scheme are the rules of adopting an appropriate sensitivity test scheme according to different patient information, disease information, and allergen information to be tested. The sensitivity test management system provides a suitable sensitivity test plan for patients who need a sensitivity test based on patient information, disease information, information on allergens to be tested, and the rules of the sensitivity test plan.
敏感性试验结果分析的规则是根据不同的患者信息、疾病信息、待测过敏物信息和敏感性试验的数据,给出敏感性试验结果的规则。敏感性试验管理系统通过信息获取单元获取敏感性试验的数据,并通过分析单元结合患者信息、疾病信息、待测过敏物信息,对敏感性试验的数据进行分析,得到敏感性试验的结果。The rules for the analysis of sensitivity test results are the rules for giving the results of sensitivity tests based on different patient information, disease information, information on allergens to be tested and sensitivity test data. The sensitivity test management system obtains the data of the sensitivity test through the information acquisition unit, and analyzes the data of the sensitivity test through the analysis unit combining patient information, disease information, and allergen information to obtain the result of the sensitivity test.
本发明的敏感性试验管理数据库还可以包括待测过敏物过敏反应的相关信息,如:待测过敏物的使用方法/剂量/时间/频率/间隔等与过敏反应的关系、待测过敏物可能出现的过敏反应以及可能影响该过敏反应的因素和出现该过敏反应后的处理措施,具体包括:过敏反应相关影响因素、过敏反应的症状/指标信号/表现/感受/严重程度/危害、过敏反应处理、过敏反应预防方法、过敏反应出现后的补救措施等。The sensitivity test management database of the present invention can also include relevant information on allergic reactions of the allergens to be tested, such as: the relationship between the use method/dose/time/frequency/interval of the allergens to be tested and the allergic reaction, the possibility of the allergens to be tested Allergic reactions and the factors that may affect the allergic reactions and the treatment measures after the allergic reactions occur, specifically including: related influencing factors of allergic reactions, symptoms/indicator signals/manifestations/feelings/severity/harm of allergic reactions, allergic reactions Treatment, allergic reaction prevention methods, remedial measures after allergic reaction occurs, etc.
本发明的敏感性试验管理数据库还可以包括过敏反应与待测过敏物使用监测方案的相关信息,如:监测相关待测过敏物浓度、监测相关指标、监测相关症状、监测相关生理状况等,用于获取及分析药物使用过程中或药物使用后与过敏反应相关的实际情况。The sensitivity test management database of the present invention can also include information related to allergic reactions and the use monitoring scheme of the allergen to be tested, such as: monitoring the concentration of the allergen to be tested, monitoring related indicators, monitoring related symptoms, monitoring related physiological conditions, etc. Facts related to allergic reactions during or after drug use are obtained and analyzed.
本发明的敏感性试验管理数据库还可以包括:过敏相关信息及与过敏反应类型/过敏反应程度分级/过敏反应影响的信息,其中过敏反应影响又可以分为过敏反应影响类型和影响级别、以及具体的 影响后果。其中过敏反应的类型可以包括:I型(速发型);Ⅱ型(细胞毒型);Ⅲ型(免疫复合物型);Ⅳ型(迟发型)。待测过敏物过敏反应影响类型可以包括:疗效的增强/减弱、起效时间的缩短/延长、毒性的增加/减少、治疗成本的增加/减少、依从性的增强/减弱等;过敏反应影响级别可以设定为可忽略、轻微、中度、重度、严重、危险、禁止等。The sensitivity test management database of the present invention can also include: allergy-related information and information related to allergic reaction type/allergic reaction degree grading/allergic reaction impact, wherein the allergic reaction impact can be further divided into allergic reaction impact type and impact level, and specific consequences of the impact. The type of allergic reaction may include: type I (immediate type); type II (cytotoxic type); type III (immune complex type); type IV (delayed type). The type of allergic reaction impact of the allergens to be tested may include: enhancement/weakening of curative effect, shortening/prolongation of onset time, increase/decrease of toxicity, increase/decrease of treatment cost, enhancement/weakening of compliance, etc.; allergic reaction impact level Can be set to ignore, minor, moderate, severe, critical, dangerous, prohibited, etc.
其次,通过信息获取单元12获取患者信息、疾病信息和待测过敏物信息。Secondly, the patient information, disease information and allergen information to be tested are acquired through the information acquisition unit 12 .
患者信息可以包括:患者基本信息、遗传相关信息、家族健康相关信息如家族病史、病史、过敏史、区域流行病史、用药史、手术史、医疗器械使用史、学习情况、工作情况、运动情况、家庭情况、生活环境、兴趣爱好、依从性情况、耐受情况、医疗保险情况,以及生理/心理/学习/工作/体能/睡眠/运动/情绪/代谢/视力/听力/智力/注意力/饮食/免疫/生长发育/记忆力/生育能力状况和作息时间等信息。Patient information can include: basic patient information, genetic related information, family health related information such as family medical history, medical history, allergy history, regional epidemiological history, medication history, operation history, medical device use history, learning situation, work situation, exercise situation, Family situation, living environment, hobbies, compliance, tolerance, medical insurance, and physiology/psychology/study/work/physical fitness/sleep/exercise/emotion/metabolism/vision/hearing/intelligence/attention/diet /immunity/growth and development/memory/fertility status and work and rest time and other information.
疾病信息可以包括:患者的各种生理/心理/学习/工作/体能/睡眠/运动/情绪/代谢/视力/听力/智力/注意力/食欲/免疫/生长发育/记忆力/生育能力/遗传相关信息等的指标、参数、状态或状况;对疾病/症状/指标等通过问询、检查、检测、试验、实验、手术、评估、评价、观察所得到的信息;与患者生长发育/生育/避孕/辅助生殖/心理需求/学习需求/工作需求/运动需求/娱乐需求/营养需求/热量需求等有关的信息;患者的手术/操作/检查/检测/监测/评估/评价/分析/预测/理疗/热疗/光疗/磁疗/电疗/康复/保健/免疫治疗/基因治疗等信息;患者的药品/医疗器械/保健品/化妆品等相关的信 息。Disease information can include: various physiological/mental/study/work/physical fitness/sleep/exercise/emotional/metabolism/vision/hearing/intelligence/attention/appetite/immunity/growth and development/memory/fertility/genetic correlations of the patient Indicators, parameters, states or conditions of information, etc.; information obtained through inquiry, inspection, detection, test, experiment, operation, evaluation, evaluation, and observation of diseases/symptoms/indicators; and patient growth and development/birth/contraception /Assisted reproduction/Psychological needs/Learning needs/Working needs/Sports needs/Entertainment needs/Nutrition needs/calorie needs, etc.; patient's surgery/operation/examination/detection/monitoring/assessment/evaluation/analysis/prediction/physiotherapy /Heat therapy/Phototherapy/Magnet therapy/Electrotherapy/Rehabilitation/Health care/Immunotherapy/Gene therapy and other information; Information about patients' medicines/Medical devices/Health care products/Cosmetics etc.
待测过敏物信息包括:待测过敏物的名称、成分、浓度、接触方法等信息。例如:待测过敏物为药物,其信息可以包括:药物的通用名、商品名、生产企业、药物批号、药物类型、药物规格、药物剂型、给药途径、给药部位、使用方法、给药量、用药时间、用药间隔、用药频率、用药周期等信息。The information of the allergen to be tested includes: the name, composition, concentration, contact method and other information of the allergen to be tested. For example, if the allergen to be tested is a drug, its information may include: drug generic name, trade name, manufacturer, drug batch number, drug type, drug specification, drug dosage form, route of administration, site of administration, method of use, administration Dosage, medication time, medication interval, medication frequency, medication cycle and other information.
信息获取单元12获取患者信息、疾病信息和待测过敏物信息的来源可以是:患者相关症状、相关指标、感受、状态、生理功能自述;患者学习、工作、生活、运动等的状态和需求自述;医疗人员开具的医嘱;患者的病历、电子病历、诊断报告、检查结果、检验结果、监测结果、评估报告;从患者个人信息数据库中获取;通过问询、检查、检测、试验、实验、手术、评估、评价、观察等方法获取的信息;事先设定的时间、季节、时辰、间隔、周期等信息;事先设定的监测各项生理、病理指标的变化等途径;患者个人信息数据库、健康档案、家庭或家族成员健康记录、医嘱、病历、药历、处方、电子病历、医疗机构信息系统、药店/医疗器械店信息系统、就医记录、治疗记录、评估报告、咨询记录、调查记录、作息记录/计划、饮食记录/计划、用药记录/计划、治疗记录/计划、运动记录/计划、工作记录/计划、学习记录/计划、康复记录/计划、保健记录/计划、检验/检查单、手术计划/记录、健康管理计划、收费单、临床治疗路径、检查/检验结果、手术设定/记录、基因检测结果,也可以从患者/医生/护士/看护人的使用/处方/推荐记录获得,也可以是由各种穿戴设备、传感器、电子设备、电子定位系统、天气预报系统、电子温湿度/气压检测设备、智能音箱、智能家 居系统、智能监视/监测系统、智能眼镜、智能马桶、智能地面、智能秤、智能检测/分析设备、电子输液系统、手术机器人、人脸识别分析、指纹识别、语音识别、步态识别、定位系统、社交平台等设备或系统提供,也可以是由患者生活、学习、工作、运动、出行、社交、购物、饮食、作息、娱乐等信息通过大数据分析得到,也可由患者的人种/家族/区域/年龄/婚姻/生育等相关信息分析得到。缺失信息也可以由患者/医生/护士/看护人提供或完善相关信息,也可以是将相关性高的信息主动提示患者/医生/护士/看护人去观察、监测、检查、问询、分析、确认、记录是否出现相关情况或获取相关指标/表现/感受/症状/生理改变,相关性是由设定或通过数据分析的把各项相关要素按照对治疗方案合理及合规性在有效性、安全性、经济性、适宜性/舒适性/依从性等方面的重要性进行分级或排序,对重要性较高的可以设定为必须完善否则不能进行下一步的信息。获取患者治疗方案的相关要素实际信息时,还可以根据医疗人员个人信息数据库对特定医疗人员开具的相关医疗信息进行分析,以便进一步准确掌握相关要素的实际信息。评估报告包括生理、心理、经济、信用、运动能力等。智能检测/分析设备包括:气味、图像、声音、脉象、X光片、CT、核磁、超声波检查、脑电波、质谱分析仪、舌诊分析、眼底检查、胃镜、肠镜、导管、微创镜、心率、血氧量、血压、血糖、血脂、体温、血液检查、尿液检查、粪便检查、脉博测量/分析设备等。The sources for the information acquisition unit 12 to acquire patient information, disease information, and allergen information to be tested can be: patient-related symptoms, related indicators, feelings, states, physiological function self-reports; patient self-reports on the states and needs of study, work, life, sports, etc. ; Medical orders issued by medical personnel; patient's medical records, electronic medical records, diagnostic reports, examination results, test results, monitoring results, evaluation reports; obtained from the patient's personal information database; through inquiry, examination, detection, test, experiment, operation Information obtained by methods such as evaluation, evaluation, observation, etc.; pre-set time, season, hour, interval, cycle and other information; pre-set ways to monitor changes in various physiological and pathological indicators; patient personal information database, health Archives, family or family member health records, doctor's orders, medical records, drug records, prescriptions, electronic medical records, medical institution information systems, pharmacy/medical device store information systems, medical records, treatment records, evaluation reports, consultation records, investigation records, schedules Records/plans, diet records/plans, medication records/plans, treatment records/plans, exercise records/plans, work records/plans, study records/plans, rehabilitation records/plans, health care records/plans, inspections/checklists, operations Plans/records, health management plans, bills, clinical treatment paths, examination/test results, surgical settings/records, genetic test results, can also be obtained from patient/doctor/nurse/caregiver use/prescription/recommendation records, It can also be composed of various wearable devices, sensors, electronic devices, electronic positioning systems, weather forecast systems, electronic temperature and humidity/air pressure detection equipment, smart speakers, smart home systems, smart monitoring/monitoring systems, smart glasses, smart toilets, smart Ground, smart scales, smart detection/analysis equipment, electronic infusion systems, surgical robots, face recognition analysis, fingerprint recognition, voice recognition, gait recognition, positioning systems, social platforms and other equipment or systems, can also be provided by patients’ life , Study, work, exercise, travel, social interaction, shopping, diet, work and rest, entertainment and other information can be obtained through big data analysis, and can also be obtained by analyzing relevant information such as the patient's race/family/region/age/marriage/birth. The missing information can also be provided or improved by the patient/doctor/nurse/caregiver, or the highly relevant information can be actively prompted to the patient/doctor/nurse/caregiver to observe, monitor, check, inquire, analyze, Confirm and record whether there is a relevant situation or obtain relevant indicators/performance/feeling/symptoms/physiological changes. The correlation is determined by setting or through data analysis. The importance of safety, economy, suitability/comfort/compliance, etc. is graded or sorted, and the information with higher importance can be set as the information that must be completed or the next step cannot be carried out. When obtaining the actual information of the relevant elements of the patient's treatment plan, it is also possible to analyze the relevant medical information issued by specific medical personnel according to the database of medical personnel's personal information, so as to further accurately grasp the actual information of the relevant elements. Evaluation reports include physical, psychological, economic, credit, athletic ability, etc. Intelligent detection/analysis equipment includes: smell, image, sound, pulse condition, X-ray film, CT, nuclear magnetic resonance, ultrasonic examination, brain wave, mass spectrometer, tongue analysis, fundus examination, gastroscope, colonoscopy, catheter, minimally invasive mirror , heart rate, blood oxygen level, blood pressure, blood sugar, blood lipid, body temperature, blood test, urine test, feces test, pulse measurement/analysis equipment, etc.
在本发明中,数据库单元11还可以存储有患者个人信息数据库,所述患者个人信息数据库中包括患者的相关信息,用于提供或补充患者信息。患者个人信息数据库中包括患者的相关信息,其内容包括:患者基本信息、遗传相关信息、家族健康相关信息如家族 病史、病史、过敏史、区域流行病史、用药史、手术史、医疗器械使用史、学习情况、工作情况、运动情况、家庭情况、生活环境、兴趣爱好、依从性情况、耐受情况、医疗保险情况,以及生理/心理/学习/工作/体能/睡眠/运动/情绪/代谢/视力/听力/智力/注意力/饮食/免疫/生长发育/记忆力/生育能力状况和作息时间等信息。In the present invention, the database unit 11 may also store a patient personal information database, which includes relevant information of the patient for providing or supplementing the patient information. The patient's personal information database includes relevant information of the patient, including: basic patient information, genetic information, and family health information such as family medical history, medical history, allergy history, regional epidemic history, medication history, surgical history, and medical device use history , study situation, work situation, sports situation, family situation, living environment, hobbies, compliance situation, tolerance situation, medical insurance situation, and physical/psychological/study/work/physical fitness/sleep/exercise/emotion/metabolism/ Information about vision/hearing/intelligence/attention/diet/immunity/growth/development/memory/fertility and work and rest time.
然后,由分析单元13根据患者信息、疾病信息、待测过敏物信息和需要做敏感性试验的规则进行分析,评估是否需要做敏感性试验。Then, the analysis unit 13 conducts analysis according to the patient information, disease information, allergen information to be tested and the rules requiring a sensitivity test to evaluate whether a sensitivity test is required.
获取患者信息、疾病信息和待测过敏物信息之后,分析单元13将患者信息、疾病信息和待测过敏物信息与敏感性试验管理数据库中的需要做敏感性试验的规则进行比对,分析得出该患者是否需要做敏感性试验的分析结果。After obtaining the patient information, disease information, and allergen information to be tested, the analysis unit 13 compares the patient information, disease information, and allergen information to be tested with the rules in the sensitivity test management database that require a sensitivity test, and analyzes Determine whether the patient needs to do the analysis results of the sensitivity test.
本发明的敏感性试验管理系统,数据库单元11还可以存储有敏感性试验要素属性字典,用于处理获取的来自不同来源、不同数据结构、不同描述、不同数据标准的信息与数据库单元中的相关信息和规则的匹配/比对。敏感性试验要素属性字典其中包含敏感性试验相关各要素属性的标准字典、异名对应字典、模糊匹配字典中的至少一个,包括上述各项涉及的各维度要素属性的异名、结构、组合以及相互对应关系等数据。匹配/比对可以是使用获取的原始信息与敏感性试验要素属性字典所带的各项目异名对应字典进行对照,也可是首先将获取的原始信息转换对应各标准字典后再与敏感性试验管理数据库进行对照,或者将获取的原始信息与敏感性试验管理数据库各字典进行模糊匹配对照使用,或者是上述方法的组合。敏感性试验要素属性字典可以单独建立,也可以包括在敏感性试验管理 数据库中。In the sensitivity test management system of the present invention, the database unit 11 can also store a sensitivity test element attribute dictionary, which is used to process information obtained from different sources, different data structures, different descriptions, and different data standards and the correlation in the database unit. Matching/comparison of information and rules. Sensitivity test element attribute dictionary, which contains at least one of the standard dictionary, corresponding dictionary of different names, and fuzzy matching dictionary of each element attribute related to sensitivity test, including the different names, structures, combinations and Correspondence data and so on. Matching/comparison can be done by using the obtained original information to compare with the dictionaries corresponding to different names of the items in the sensitivity test element attribute dictionary, or by first converting the obtained original information into corresponding standard dictionaries and then matching them with sensitivity test management database, or use fuzzy matching between the obtained original information and the dictionaries of the sensitivity test management database, or a combination of the above methods. The attribute dictionary of sensitivity test elements can be established separately, or it can be included in the sensitivity test management database.
在本发明中,除了采用敏感性试验要素属性字典进行匹配,还可以通过语音识别技术、语义识别技术、不同语言的翻译、OCR识别技术、虚拟现实技术、增强现实技术、手势识别技术等方法处理获取的信息与数据库单元中相关信息和规则的匹配/比对。In the present invention, in addition to using the sensitivity test element attribute dictionary for matching, it can also be processed by speech recognition technology, semantic recognition technology, translation of different languages, OCR recognition technology, virtual reality technology, augmented reality technology, gesture recognition technology, etc. The matching/comparison of the obtained information with the relevant information and rules in the database unit.
本发明的敏感性试验管理系统,评估得出是否需要做敏感性试验的结果后,对于需要做敏感性试验的患者,还可以给出适合的敏感性试验方案。敏感性试验方案可以采用皮试,也可以采用其他方式。皮试的部位可以选用前臂曲侧,也可以选用上臂或背部皮肤。具体试验方法可以采用皮内试验、挑刺试验或斑贴试验。The sensitivity test management system of the present invention can also provide a suitable sensitivity test plan for patients who need a sensitivity test after evaluating the results of whether a sensitivity test is required. Sensitivity testing protocols may use skin testing or other methods. The skin test site can be selected from the curved side of the forearm, or the skin of the upper arm or back. Specific test methods can use intradermal test, prick test or patch test.
敏感性试验方案是根据患者信息、疾病信息和待测过敏物信息,所给出的适合的方案。本发明的敏感性试验管理系统,敏感性试验方案的规则还可以包括选择敏感性试验方案的标准和各种不同情况下的常用方案,相关标准和常用方案可以是由专家人工设定,也可以是在获取大量实例后,进行数据集合,评估是否有共性特征,对有共性特征的要素组合,使用各种相关统计学方法、大数据监测等方法建立,还可以是基于循证医学的方法,或基于现有数据的概率推测,还可以包括需要人工设定的各种权重/各种等级/各种排序等来源建立的,也可以包括基于信息重整/信息分析/大数据分析建立的,也可以包括通过人工智能深度学习建立的,也可以包括通过数据挖据分析后得出的,也可以包括通过数据统计分析/人工智能深度学习后得经过人工设定出的,也可以是在通过临床医生、药师在疾病诊疗过程中不断积累和细化而建立的,也可以是通过上述方法组合建立,并且可以在使用过程中不断积累及优化。The sensitivity test protocol is an appropriate protocol given based on patient information, disease information, and allergen information to be tested. In the sensitivity test management system of the present invention, the rules of the sensitivity test scheme can also include the criteria for selecting the sensitivity test scheme and common schemes in various situations. The relevant standards and common schemes can be manually set by experts, or can be After obtaining a large number of examples, conduct data collection, evaluate whether there are common characteristics, and use various related statistical methods, big data monitoring and other methods to establish the combination of elements with common characteristics, and can also be based on evidence-based medicine. Or based on the probability speculation of existing data, it can also include the establishment of various weights/various levels/various rankings that need to be manually set, and can also include establishment based on information reorganization/information analysis/big data analysis, It can also include those established through deep learning of artificial intelligence, or obtained through data mining and analysis, or manually set through statistical analysis of data/deep learning of artificial intelligence, or through It can be established by clinicians and pharmacists through continuous accumulation and refinement in the process of disease diagnosis and treatment, or it can be established through a combination of the above methods, and can be continuously accumulated and optimized during use.
本发明的敏感性试验管理系统,还可以通过信息获取单元12获取敏感性试验的数据,并通过分析单元13对敏感性试验的数据结合敏感性试验结果分析的规则进行分析,得到敏感性试验的结果。The sensitivity test management system of the present invention can also obtain the data of the sensitivity test through the information acquisition unit 12, and analyze the data of the sensitivity test in combination with the rules of the sensitivity test result analysis through the analysis unit 13, and obtain the sensitivity test result. result.
信息获取单元12获取敏感性试验的数据,可以包括:各种敏感性试验的指标、皮肤影像、皮肤产生红肿等变化的位置/颜色/面积/高度等等。The information acquiring unit 12 acquires the data of the sensitivity test, which may include: indicators of various sensitivity tests, skin images, position/color/area/height of changes such as skin redness and swelling, etc.
分析单元13对敏感性试验的数据进行分析,可以采用量化的方式,制定一定的标准,通过对敏感性试验的指标、图像数据等进行精确分析,得到精确的结果,从而避免依据医生个人的经验进行分析而导致给出的结果错误。例如:可以对敏感性试验的影像数据进行识别,通过红肿部位的位置、颜色、面积、高度中的至少一项,分析得出敏感性试验的结果。The analysis unit 13 analyzes the data of the sensitivity test, and can adopt a quantitative method to formulate certain standards, and obtain accurate results through precise analysis of the indicators and image data of the sensitivity test, so as to avoid relying on the doctor's personal experience. Performing the analysis results in incorrect results. For example: the image data of the sensitivity test can be identified, and at least one of the position, color, area, and height of the red and swollen part can be analyzed to obtain the result of the sensitivity test.
敏感性试验结果分析的规则可以包括敏感性试验结果的分析标准。敏感性试验结果的分析标准可以是由专家人工设定,也可以是在获取大量实例后,进行数据集合,评估是否有共性特征,对有共性特征的要素组合,使用各种相关统计学方法、大数据监测等方法建立,还可以是基于循证医学的方法,或基于现有数据的概率推测,还可以包括需要人工设定的各种权重/各种等级/各种排序等来源建立的,也可以包括基于信息重整/信息分析/大数据分析建立的,也可以包括通过人工智能深度学习建立的,也可以包括通过数据挖据分析后得出的,也可以包括通过数据统计分析/人工智能深度学习后得经过人工设定出的,也可以是在通过临床医生、药师在疾病诊疗过程中不断积累和细化而建立的,也可以是通过上述方法组合建立,并且可以在使用过程中不断积累及优化。The rules for analysis of sensitivity test results may include analysis criteria for sensitivity test results. The analysis standard of the sensitivity test results can be manually set by experts, or after obtaining a large number of examples, data collection can be carried out to evaluate whether there are common characteristics, and for the combination of elements with common characteristics, various relevant statistical methods, The establishment of methods such as big data monitoring can also be based on methods of evidence-based medicine, or based on probability speculation based on existing data, and can also include sources such as various weights/various levels/various sorts that need to be manually set. It can also include those established based on information reorganization/information analysis/big data analysis, or those established through artificial intelligence deep learning, or those obtained through data mining analysis, or those obtained through data statistical analysis/manual After intelligent deep learning, it must be manually set, or it can be established through the continuous accumulation and refinement of clinicians and pharmacists in the process of disease diagnosis and treatment, or it can be established through a combination of the above methods, and can be used during use Continuous accumulation and optimization.
本发明的敏感性试验管理系统,还可以根据敏感性试验的结果和患者信息、疾病信息、待测过敏物信息进行评估,给出评估结果。The sensitivity test management system of the present invention can also evaluate according to the results of the sensitivity test and patient information, disease information, and allergen information to be tested, and give the evaluation results.
分析单元13可以根据在不同的患者信息和疾病信息的条件下,待测过敏物在包括安全性、有效性、经济性、适宜性中的至少一项分析项目的不同分析结果,分别设定对应的级别/分值,在进行待测过敏物评估时,能够根据待测过敏物在各分析项目所对应的级别/分值以及设置的待测过敏物评估模型,计算出不同待测过敏物的综合级别/分值。用于进行待测过敏物评估,包括对不同待测过敏物或待测过敏物方案的比较。The analysis unit 13 can respectively set corresponding When evaluating the allergens to be tested, the levels/scores of the allergens to be tested can be calculated according to the corresponding levels/scores of the allergens to be tested in each analysis item and the set evaluation model of the allergens to be tested. Comprehensive level/point value. Used for test allergen assessments, including comparisons of different test allergens or test allergen regimens.
在本发明中,可以从待测过敏物应用的安全、有效、经济、适宜等项目,进行待测过敏物评估,分析患者的待测过敏物的应用方案是否适合。例如:如果患者对某种药物有严重的过敏反应,可能危及生命,则该药物肯定不能使用;而如果某药物只有轻微的过敏反应,但在治疗效果及药物价格都极佳,那么该药物可以考虑使用。待测过敏物评估在安全方面分析项目可以包括:过敏风险、过敏反应的严重程度、过敏试验安全性等;有效性方面分析项目可以包括:对疗效的影响以及严重程度等;经济性方面分析项目可以包括:治疗费用及金额等;适宜性方面分析项目可以包括:依从性的影响等。在进行待测过敏物评估时,可以根据不同业务单元的业务需要,设置由各分析项目分析结果构成的待测过敏物评估模型,以便通过各分析项目与待测过敏物评估的关系以及得出综合评估结果。这里的业务单元可以是以行政、医疗机构、科室、医生、用户、药物、疾病等各维度及组合对业务场景进行划分。In the present invention, the allergens to be tested can be evaluated from the safety, effectiveness, economy, and suitability of the application of the allergens to be tested, and whether the application plan of the allergens to be tested is suitable for the patient can be analyzed. For example: if a patient has a severe allergic reaction to a certain drug, which may be life-threatening, the drug must not be used; and if a drug has only a mild allergic reaction, but the therapeutic effect and price of the drug are excellent, then the drug can be used Consider using. The safety analysis items of the evaluation of the allergens to be tested can include: allergic risk, the severity of allergic reactions, the safety of allergy tests, etc.; the effectiveness analysis items can include: the impact on curative effect and severity, etc.; the economic analysis items It can include: treatment cost and amount, etc.; the suitability analysis items can include: the impact of compliance, etc. When evaluating the allergens to be tested, according to the business needs of different business units, an evaluation model of the allergens to be tested composed of the analysis results of each analysis item can be set up, so that the relationship between each analysis item and the evaluation of the allergens to be tested can be obtained. Comprehensive assessment results. The business units here can be divided into business scenarios based on various dimensions and combinations such as administration, medical institutions, departments, doctors, users, drugs, and diseases.
待测过敏物评估模型可以是由专家人工设定建立,也可以是在获取大量实例后,进行数据集合,评估是否有共性特征,对有共性特征的要素组合,使用各种相关统计学方法、大数据监测等方法建立。模型的建立可以是基于循证医学的方法,或基于现有数据的概率推测,还可以包括需要人工设定的各种权重/各种等级/各种排序等来源建立的,也可以包括基于信息重整/信息分析/大数据分析建立的,也可以包括通过人工智能深度学习建立的,也可以包括通过数据挖据分析后得出的,也可以包括通过数据统计分析/人工智能深度学习后得经过人工设定出的,也可以是在通过临床医生、药师在疾病诊疗过程中不断积累和细化而建立的。模型的各项参数可以是由专家人工设定的,或者通过数据统计/分析而得到的,或者通过信息重整/大数据分析得到的,或者通过人工智能深度学习/优化后得到的,并且可以在使用过程中不断积累及优化。The evaluation model of the allergens to be tested can be manually set and established by experts, or after obtaining a large number of examples, data collection can be carried out to evaluate whether there are common characteristics. For the combination of elements with common characteristics, various relevant statistical methods, Establish methods such as big data monitoring. The establishment of the model can be based on the method of evidence-based medicine, or based on the probability speculation of existing data, and can also include the establishment of various weights/various levels/various rankings that need to be manually set, and can also include information-based Reorganization/information analysis/big data analysis can also include those established through artificial intelligence deep learning, data mining and analysis, and data statistical analysis/artificial intelligence deep learning. It is manually set, or it can be established through the continuous accumulation and refinement of clinicians and pharmacists in the process of disease diagnosis and treatment. The parameters of the model can be manually set by experts, or obtained through data statistics/analysis, or obtained through information reorganization/big data analysis, or obtained through artificial intelligence deep learning/optimization, and can be Continuously accumulate and optimize during use.
在本发明中,待测过敏物评估的综合级别/分值,可以用于给出待测过敏物评估的结果,或者用于待测过敏物或待测过敏物方案相互之间进行比较。可以是预先设定一定的阈值,在进行待测过敏物评估时,计算出不同待测过敏物或待测过敏物方案的综合级别/分值,与预先设定的阈值进行比较,给出待测过敏物评估的结果。可以是预先设定不同级别的阈值,例如:提醒级、制止级、警告级、建议级、推荐级、报告级等。In the present invention, the comprehensive grade/score value of the test allergen assessment can be used to give the test allergen assessment result, or to compare the test allergen or the test allergen schemes with each other. A certain threshold can be set in advance. When evaluating the allergen to be tested, the comprehensive level/score of different allergens to be tested or the scheme of the allergen to be tested is calculated, compared with the preset threshold, and the to-be-tested allergen is given. The results of the allergy assessment. Thresholds of different levels can be preset, for example: reminder level, prohibition level, warning level, suggestion level, recommendation level, report level, etc.
本发明的敏感性试验管理系统,还可以根据待测过敏物评估结果对患者的原待测过敏物应用方案进行优化与调整。具体应用方案优化与调整的方法可以包括:调整相关待测过敏物使用方案、调整相关待测过敏物、开展相关待测过敏物使用监测或其他治疗方法等 至少一种。The sensitivity test management system of the present invention can also optimize and adjust the application plan of the patient's original allergen to be tested according to the evaluation result of the allergen to be tested. The method for optimizing and adjusting the specific application plan may include: adjusting the use plan of the relevant test allergen, adjusting the relevant test allergen, carrying out the use monitoring of the relevant test allergen or other treatment methods, etc. at least one.
以待测过敏物为药物为例。调整相关药物使用方案包括:调整相关药物用药时间方案、调整相关药物使用方法方案等。具体包括:调整给药频率、调整药物之间用药时间间隔、调整给药途径、调整给药部位、调整使用方法等至少一项,也可以两项及以上的组合。Take the allergen to be tested as a drug as an example. Adjustment of the relevant drug usage plan includes: adjustment of the relevant drug administration time plan, adjustment of the relevant drug use method plan, etc. Specifically, it includes: at least one of adjusting the frequency of administration, adjusting the time interval between medications, adjusting the route of administration, adjusting the site of administration, and adjusting the method of use, etc., or a combination of two or more.
以上所述调整相关药物用药时间,指通过调整药物的给药频率或服药时间以降低或消除过敏反应的影响。通过药代动力学、疾病特性、用户依从性等因素综合分析相关药物使用时间可能调整的范围。具体调整方法为:根据药物过敏反应影响与药物使用时间间隔关系,以及可能存在一定的过敏反应风险的各药物合理的用药时间范围,可以得出的在符合相关药物合理用药时间范围的条件下将过敏反应影响降到最低的药物用药时间方案即为药物使用时间优化方案。药物使用时间优化方案可以是一个也可以是多个时间方案的合集。如:用户对A药和B药在体内共同作用生成的新产物C过敏,可以通过调整A或B的用药时间,延长两药的给药间隔,避免产物C的生成,从而消除这种过敏反应的影响。The above-mentioned adjustment of the administration time of relevant drugs refers to reducing or eliminating the influence of allergic reactions by adjusting the administration frequency or time of administration of the drugs. Comprehensively analyze the range of possible adjustments in the use time of related drugs based on factors such as pharmacokinetics, disease characteristics, and user compliance. The specific adjustment method is: according to the relationship between the impact of drug allergic reaction and the time interval of drug use, as well as the reasonable drug use time range of each drug that may have a certain risk of allergic reaction, it can be obtained that the relevant drug is in line with the reasonable drug use time range. The drug administration time plan that minimizes the impact of allergic reactions is the optimal drug use time plan. The drug use time optimization scheme may be one or a collection of multiple time schemes. For example, if the user is allergic to the new product C produced by the joint action of drug A and drug B in the body, the allergic reaction can be eliminated by adjusting the administration time of A or B, prolonging the interval between the two drugs, and avoiding the generation of product C. Impact.
以上所述调整相关药物使用方法,指通过调整给药途径、调整给药部位、调整使用方法,降低或消除过敏反应影响。通过药代动力学、疾病特性、用户依从性等因素综合分析相关药物使用方法可能调整的范围。如:某些外用药用于脸部会出现过敏反应,用于其他身体部位时无过敏现象,可以通过调整给药部位,避免用于敏感性皮肤部位来降低或消除过敏反应影响。Adjusting the usage method of relevant drugs mentioned above refers to reducing or eliminating the impact of allergic reactions by adjusting the route of administration, the site of administration, and the method of use. Comprehensively analyze the range of possible adjustments of relevant drug usage methods through pharmacokinetics, disease characteristics, user compliance and other factors. For example, some external medicines will cause allergic reactions when used on the face, but there is no allergic phenomenon when used on other parts of the body. You can reduce or eliminate the impact of allergic reactions by adjusting the administration site and avoiding use on sensitive skin parts.
调整相关药物包括在原用药方案的基础上:减少药物、增加药物、更换药物等至少一项。具体包括:将可能存在一定的过敏反应风险的药物从用药方案中排除,将可能存在一定的过敏反应风险的药物更换为具有相同临床作用但过敏反应风险较小的其他药物,在现有用药方案基础上,增加新的药物以降低原有过敏反应风险等。Adjustment of relevant drugs includes at least one of the following: reducing drugs, increasing drugs, changing drugs, etc. on the basis of the original drug regimen. Specifically, it includes: excluding drugs that may have a certain risk of allergic reaction from the drug regimen, replacing drugs that may have a certain risk of allergic reaction with other drugs that have the same clinical effect but have a lower risk of allergic reaction. On this basis, new drugs are added to reduce the risk of original allergic reactions.
以上所述减少药物,指通过停用原用药方案中的一种或几种药物,降低或消除过敏反应的影响。停用药物的选择,因素可以包括该药物是否某一适应症的首选/一线治疗方案、该药物是否长期用药等。如:2型糖尿病患者联合使用二甲双胍和磺脲类降糖药,假设患者加用磺脲类前单用二甲双胍血糖控制已达标,且患者有磺胺类药物过敏史,可通过停用磺脲类来消除过敏反应风险。The reduction of drugs mentioned above refers to reducing or eliminating the impact of allergic reactions by stopping one or several drugs in the original drug regimen. The choice of drug discontinuation may include whether the drug is the preferred/first-line treatment for a certain indication, whether the drug is used for a long time, etc. For example: patients with type 2 diabetes mellitus combined with metformin and sulfonylurea hypoglycemic drugs, assuming that the blood sugar control of the patient has reached the target with metformin alone before adding sulfonylureas, and the patient has a history of allergy to sulfonylureas, it can be stopped by stopping the sulfonylureas. Eliminates the risk of allergic reactions.
以上所述更换药物,指通过更换原用药方案中的一种或几种药物,降低或消除过敏反应的影响。更换药物包括更换剂型、更换规格、更换厂家、更换药品名称等。原用药方案中的药物是否可更换,因素可以包括该药物是否某一适应症的首选/一线治疗方案、该药物是否有可替代品、当前业务单元是否有该药物的替代品、该药物是否长期用药等。如:有磺胺类药物过敏史的2型糖尿病患者服用磺脲类降糖药,可能会发生交叉过敏,可将磺脲类换成双胍类、葡萄糖苷酶抑制剂等其他口服降糖药。The above-mentioned replacement of drugs refers to reducing or eliminating the impact of allergic reactions by replacing one or several drugs in the original drug regimen. Changing medicines includes changing dosage forms, changing specifications, changing manufacturers, changing drug names, etc. Whether the drug in the original drug regimen can be replaced, factors can include whether the drug is the preferred/first-line treatment for a certain indication, whether the drug has an alternative, whether the current business unit has an alternative to the drug, whether the drug is long-term Medication, etc. For example, patients with type 2 diabetes who have a history of allergy to sulfonamides may experience cross-allergies when taking sulfonylureas. The sulfonylureas can be replaced by other oral hypoglycemic agents such as biguanides and glucosidase inhibitors.
以上所述增加药物,指通过在原用药方案的基础上增加新的药物,降低或消除过敏反应的影响。增加药物以预防或治疗原用药方案可能引起的过敏反应,或与原用药方案中的药物相互作用产生新的临床作用或减弱原用药方案中的药物毒性,以降低或消除原用药方案中过敏反应的影响。如:接受紫杉醇注射液治疗的用户超敏反 应发生率高达30%~41%,可在紫杉醇注射液输注前,通过糖皮质激素加H1和H2受体拮抗剂进行预处理,以预防超敏反应的发生。Adding drugs as mentioned above refers to reducing or eliminating the impact of allergic reactions by adding new drugs on the basis of the original drug regimen. Add drugs to prevent or treat allergic reactions that may be caused by the original drug regimen, or interact with drugs in the original drug regimen to produce new clinical effects or reduce drug toxicity in the original drug regimen, so as to reduce or eliminate allergic reactions in the original drug regimen Impact. For example, the incidence of hypersensitivity reactions among users receiving paclitaxel injection is as high as 30% to 41%. Pretreatment with glucocorticoids plus H1 and H2 receptor antagonists can be performed before infusion of paclitaxel injection to prevent hypersensitivity. reaction occurs.
以上所述相关用药监测方案包括:监测相关药物血药浓度、监测相关指标、监测相关症状、监测相关生理状况等至少一项。如:患者可能对某种药物过敏,但没有替换方案的情况下,可密切监测患者的相关指标、症状等,一旦出现过敏指征,立即停用该药物。The above-mentioned relevant medication monitoring scheme includes at least one of: monitoring the blood drug concentration of relevant drugs, monitoring related indicators, monitoring related symptoms, and monitoring related physiological conditions. For example, if a patient may be allergic to a certain drug, but there is no replacement plan, the relevant indicators and symptoms of the patient can be closely monitored. Once allergic indications appear, the drug should be stopped immediately.
以上所述其他治疗方法包括:手术、理疗、中医疗法、心理治疗、康复治疗、综合健康管理等至少一项。The above-mentioned other treatment methods include: at least one of surgery, physical therapy, traditional Chinese medicine therapy, psychotherapy, rehabilitation therapy, and comprehensive health management.
对用药方案进行优化的方法还可以是上述方法的组合,即调整相关药物用药时间方案、调整相关药物使用方法方案、减少药物、增加药物、更换药物、开展相关用药监测、使用其他治疗方法等方法中两种或两种以上同时采用的情况。The method of optimizing the drug regimen can also be a combination of the above methods, that is, adjusting the time regimen of relevant drug administration, adjusting the regimen of relevant drug usage, reducing drugs, increasing drugs, changing drugs, carrying out relevant drug monitoring, using other treatment methods, etc. Two or more of them are used at the same time.
在本发明中,敏感性试验管理系统给出的是否需要做敏感性试验、敏感性试验的结果和待测过敏物评估结果,可以用于辅助提醒、警告、限制、禁止、协助、指导患者/医生/护士/看护人进行治疗。也可以用于患者/医生/护士/看护人与推荐/管理/指导/咨询岗位或二级推荐/管理/指导/咨询中心讨论以及高级岗位回复/自动回复的数据基础。也可以事后作为医生/护士/看护人等人员专业水平评价/专业规范性评价/绩效评价/绩效考核的依据。也可以作为无人售货机/电商/药店/医疗机构销售或拒绝销售的依据。也可以与各种信息系统/信息平台/各种无人售货机/智能穿戴设备/智能家居设备/智能医疗器械/医疗设备/远程控制医疗器械联通,作为系统或相关设备触发下相关操作或流程的可配置控制项目,如自动售货、智能 提醒、智能启动、智能关闭等。也可以作为医保管理机构/医疗保险公司/卫生行政管理部门/信用评价机构/等级评审机构/司法机构评价、考核、监督、执法、管理、裁判医疗机构/药店/医疗器械零售店相关业务行为的依据,也可以用于监护者/家庭医生/家庭药师/健康管理师/家庭护理管理患者的治疗/康复/保健/检查的依据,也可以用于智能健康管理系统/疾病管理系统对患者的健康管理/疾病管理,也可以用于科研机构/科研人员/生产企业/销售企业/使用机构/采购机构/患者/医生/护士/药师/看护人/售货员等相关对象选择/评估/设计/研发/销售的数据依据,也可以用于医疗保险管理机构/医疗保险公司/物价管理部门/卫生行政部门/医疗机构制定手术相关政策/规定/支付范围/支付比率/支付额度/使用范围等时的数据依据。也可以对以上各项分析项目及其分析结果的反馈对象和应用进行设置,根据患者的需要,将各分析项目分析结果反馈给不同部门和不同岗位,并设置各部门、岗位的处理权限和流程以及各环节的处理时限和处理要求,也可根据管理需求生成相应各种分析结果报表。对敏感性试验管理结果的应用可以是事前推荐、事中审核、也可以是事后点评的模式。根据敏感性试验管理结果,出具的规范性评估报告,提供给医政管理人员、医疗保险机构、医疗保险管理人员、流通领域管理人员,提示可能存在的各种违规、违法行为,为进一步规范诊疗过程提供支持。In the present invention, whether a sensitivity test is required, the results of the sensitivity test, and the evaluation results of the allergens to be tested given by the sensitivity test management system can be used to assist in reminding, warning, restricting, prohibiting, assisting, and guiding patients/ Physician/Nurse/Caregiver for treatment. It can also be used for patient/doctor/nurse/caregiver and referral/management/guidance/counseling post or secondary referral/management/guidance/counseling center discussion and data basis for advanced post reply/auto-reply. It can also be used as a basis for professional level evaluation/professional normative evaluation/performance evaluation/performance appraisal of doctors/nurses/caregivers and other personnel afterwards. It can also be used as a basis for sales or refusal of sales by unmanned vending machines/e-commerce/pharmacies/medical institutions. It can also be connected with various information systems/information platforms/various unmanned vending machines/smart wearable devices/smart home devices/smart medical devices/medical devices/remote control medical devices, as related operations or processes triggered by systems or related devices Configurable control items, such as vending, smart reminder, smart start, smart shutdown, etc. It can also be used as a medical insurance management agency/medical insurance company/health administrative department/credit evaluation agency/grade review agency/judicial agency to evaluate, assess, supervise, enforce, manage, and refer to medical institutions/pharmacies/medical equipment retail stores. It can also be used as a basis for guardians/family doctors/family pharmacists/health managers/family care management patients' treatment/rehabilitation/health care/examination, and can also be used for intelligent health management systems/disease management systems for patients' health Management/disease management, can also be used for scientific research institutions/researchers/production companies/sales companies/using organizations/purchasing organizations/patients/doctors/nurses/pharmacists/caregivers/salespersons and other related objects selection/evaluation/design/development/ The data basis for sales can also be used for data when medical insurance management agencies/medical insurance companies/price management departments/health administrative departments/medical institutions formulate surgery-related policies/regulations/payment scope/payment ratio/payment amount/use scope, etc. in accordance with. It is also possible to set the feedback objects and applications of the above analysis items and their analysis results. According to the needs of patients, the analysis results of each analysis item are fed back to different departments and different positions, and the processing authority and process of each department and position are set. As well as the processing time limit and processing requirements of each link, various corresponding analysis result reports can also be generated according to management requirements. The application of sensitivity test management results can be in the mode of prior recommendation, mid-event review, or post-event evaluation. According to the management results of the sensitivity test, the normative evaluation report issued is provided to the medical administration management personnel, medical insurance institutions, medical insurance management personnel, and circulation field management personnel to prompt various violations and illegal acts that may exist, in order to further standardize diagnosis and treatment process support.
在本发明中,敏感性试验管理系统的各项分析结果以及评估、报告以及其他输出信息,可以由专业人员根据敏感性试验管理数据库以及各项数据人工完成,或者在系统的支持下人工完成,也可以让系统自动完成,也可以由人工智能自动完成,也可以系统/人工智能完成部分与手工完成部分结合的方式完成。相关敏感性试验管理 分析结果应用/输出的形式可以是提醒、通知、报表、报告、系统权限限制、系统流程限制、相关系统/设备/文件/权限的控制等功能实现;也可以是提供相关接口,与其他管理系统对接实现;也可以是提供分析结果,由用户手工实现相关分析结果的应用。In the present invention, various analysis results, assessments, reports and other output information of the sensitivity test management system can be manually completed by professionals according to the sensitivity test management database and various data, or manually completed with the support of the system, It can also be completed automatically by the system, by artificial intelligence, or by a combination of system/artificial intelligence and manual completion. The form of application/output of relevant sensitivity test management and analysis results can be reminders, notifications, reports, reports, system authority restrictions, system process restrictions, control of related systems/equipment/files/authorities, etc.; it can also be the provision of relevant interfaces It can also be implemented by connecting with other management systems; it can also be an application that provides analysis results and the user manually implements the relevant analysis results.
在本发明中,敏感性试验管理系统的患者、医疗人员以及相关角色的身份识别、确认、登录、电子签章,以及个人信息、医疗信息和各项分析结果的储存、传输和应用,可以通过各种方法进行加密,防止相关身份/权限被盗用或者信息泄露。其中加密算法包括对称加密算法和/或非对称加密算法,例如:大整数分解问题类加密算法、离散对数问题类加密算法、椭圆曲线类加密算法,具体如区块链技术等,加密硬件可以采用密钥、加密狗、加密硬盘等,还可以结合用户设备硬件、网络地址等进行加密,还可以是上述方法相互结合进行加密。In the present invention, the identification, confirmation, login, and electronic signature of patients, medical personnel, and related roles in the sensitivity test management system, as well as the storage, transmission, and application of personal information, medical information, and various analysis results can be done through Various methods are used for encryption to prevent related identities/permissions from being stolen or information leaked. The encryption algorithms include symmetric encryption algorithms and/or asymmetric encryption algorithms, such as: encryption algorithms for large integer decomposition problems, encryption algorithms for discrete logarithm problems, and elliptic curve encryption algorithms, such as blockchain technology, etc. The encryption hardware can Using keys, dongles, encrypted hard disks, etc., can also be combined with user equipment hardware, network addresses, etc. for encryption, and the above methods can also be combined for encryption.
在本发明中,敏感性试验管理系统的数据传输方式可以是数据线方式、有线网络、无线传输方式、射频识别方式、磁卡读写方式、移动硬盘方式、NFC方式、条形码方式、二维码方式等。无线传输方式包括:红外、蓝牙、wifi、微波、可见光波、电信无线网络、超声波/声波、无线电等方式。In the present invention, the data transmission mode of the sensitivity test management system can be data line mode, wired network, wireless transmission mode, radio frequency identification mode, magnetic card reading and writing mode, mobile hard disk mode, NFC mode, bar code mode, two-dimensional code mode wait. Wireless transmission methods include: infrared, bluetooth, wifi, microwave, visible light wave, telecommunications wireless network, ultrasonic/sound wave, radio and other methods.
在本发明中,敏感性试验管理系统可以以单机使用,也可以是以移动硬盘、盒子、卡等接入式外部硬件供用户使用,也可以安装在本地服务器支持本地用户使用,也可以安装在私有云服务器支持私有云用户使用,也可以安装在互联网面向互联网用户提供服务。In the present invention, the susceptibility test management system can be used as a stand-alone machine, or can be used by users with access-type external hardware such as mobile hard disks, boxes, cards, etc., or can be installed on local servers to support local users, or can be installed on The private cloud server supports the use of private cloud users, and can also be installed on the Internet to provide services to Internet users.
本发明第二实施例参阅图2。图2为本发明一种敏感性试验管 理方法的方法流程图。如图所示,本发明的敏感性试验管理方法包括:Refer to FIG. 2 for the second embodiment of the present invention. Fig. 2 is a method flowchart of a sensitivity test management method of the present invention. As shown in the figure, the sensitivity test management method of the present invention includes:
步骤1,建立敏感性试验管理数据库,所述敏感性试验管理数据库包括需要做敏感性试验的规则;Step 1, establishing a sensitivity test management database, the sensitivity test management database includes rules that require sensitivity tests;
步骤2,获取患者信息、疾病信息和待测过敏物信息;Step 2, obtaining patient information, disease information and allergen information to be tested;
步骤3,根据患者信息、疾病信息、待测过敏物信息和需要做敏感性试验的规则进行分析,评估是否需要做敏感性试验。Step 3: Analyze according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.
本发明的敏感性试验管理方法,还可以包括:The sensitivity test management method of the present invention may also include:
步骤4,获取敏感性试验的数据,并对敏感性试验的数据进行分析,得到敏感性试验的结果。Step 4, obtaining the data of the sensitivity test and analyzing the data of the sensitivity test to obtain the result of the sensitivity test.
本发明的敏感性试验管理方法,还可以包括:The sensitivity test management method of the present invention may also include:
步骤5,根据敏感性试验的结果和患者信息、疾病信息、待测过敏物信息进行待测过敏物评估,给出评估结果。Step 5: Evaluate the allergen to be tested according to the results of the sensitivity test, patient information, disease information, and allergen to be tested, and give the evaluation result.
本发明的一种敏感性试验管理方法与本发明的一种敏感性试验管理系统,技术特征一一对应,可以参照前述一种敏感性试验管理系统的说明,在此不再赘述。The sensitive test management method of the present invention corresponds to the technical features of the sensitive test management system of the present invention one by one, and reference may be made to the description of the aforementioned sensitive test management system, which will not be repeated here.
综上所述,本发明的一种敏感性试验管理系统及方法,敏感性试验管理系统包括:数据库单元、信息获取单元和分析单元。敏感性试验管理方法包括:建立敏感性试验管理数据库,获取患者信息、疾病信息和待测过敏物信息,根据患者信息、疾病信息、待测过敏物信息和需要做敏感性试验的规则进行分析,评估是否需要做敏感性试验。通过本发明的一种敏感性试验管理系统及方法,从需 要做敏感性试验的规则、试验结果的量化分析、以及根据试验结果进行待测过敏物分析等多方面进行敏感性试验管理,有利于高质量管理敏感性试验,提高医疗质量、防止过敏反应、保障患者安全等方面发挥巨大的作用。In summary, a sensitivity test management system and method of the present invention, the sensitivity test management system includes: a database unit, an information acquisition unit and an analysis unit. Sensitivity test management methods include: establishing a sensitivity test management database, obtaining patient information, disease information, and test allergen information, and performing analysis based on patient information, disease information, test allergen information, and rules requiring sensitivity tests, Assess the need for sensitivity testing. Through a sensitivity test management system and method of the present invention, sensitivity test management is carried out from various aspects such as rules for sensitivity tests, quantitative analysis of test results, and analysis of allergens to be tested according to test results, which is beneficial High-quality management of sensitivity tests plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.
以上所述的具体实施方式,对本发明的目的、技术方案和有益效果进行了进一步详细说明,所应理解的是,以上所述仅为本发明的具体实施方式而已,并不用于限定本发明的保护范围,凡在本发明的精神和原则之内,所做的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。The specific embodiments described above have further described the purpose, technical solutions and beneficial effects of the present invention in detail. It should be understood that the above descriptions are only specific embodiments of the present invention and are not intended to limit the scope of the present invention. Protection scope, within the spirit and principles of the present invention, any modification, equivalent replacement, improvement, etc., shall be included in the protection scope of the present invention.

Claims (9)

  1. 一种敏感性试验管理系统,其特征在于,所述系统包括:A sensitivity test management system, characterized in that the system includes:
    数据库单元,用于存储敏感性试验管理数据库,所述敏感性试验管理数据库包括需要做敏感性试验的规则;The database unit is used to store a sensitivity test management database, and the sensitivity test management database includes rules that require sensitivity tests;
    信息获取单元,用于获取患者信息、疾病信息和待测过敏物信息,所述待测过敏物包括:药物、饮食、医疗器械、光照、化妆品、日用品、空气、衣物中的至少一种;An information acquisition unit, configured to acquire patient information, disease information, and information on allergens to be tested, the allergens to be tested include: at least one of medicine, diet, medical equipment, light, cosmetics, daily necessities, air, and clothing;
    分析单元,用于根据患者信息、疾病信息、待测过敏物信息和需要做敏感性试验的规则进行分析,评估是否需要做敏感性试验。The analysis unit is configured to perform analysis according to the patient information, disease information, allergen information to be tested and the rules requiring a sensitivity test to evaluate whether a sensitivity test is required.
  2. 根据权利要求1所述的一种敏感性试验管理系统,其特征在于:所述敏感性试验管理数据库包括敏感性试验方案的规则,所述敏感性试验管理系统对于需要做敏感性试验的患者,给出适合的敏感性试验方案。A sensitivity test management system according to claim 1, characterized in that: the sensitivity test management database includes rules for sensitivity test schemes, and the sensitivity test management system for patients who need to do sensitivity tests, A suitable sensitivity test plan is given.
  3. 根据权利要求1所述的一种敏感性试验管理系统,其特征在于:所述数据库单元还存储有患者个人信息数据库,所述患者个人信息数据库中包括患者的相关信息,用于提供或补充患者信息。A sensitivity test management system according to claim 1, characterized in that: said database unit also stores a patient personal information database, said patient personal information database includes relevant information of the patient, for providing or supplementing patient information. information.
  4. 根据权利要求1所述的一种敏感性试验管理系统,其特征在于:所述敏感性试验管理数据库包括敏感性试验结果分析的规则,所述敏感性试验管理系统通过所述信息获取单元获取敏感性试验的数据,并通过所述分析单元对敏感性试验的数据进行分析,得到敏感性试验的结果。A sensitivity test management system according to claim 1, characterized in that: said sensitivity test management database includes rules for analysis of sensitivity test results, and said sensitivity test management system acquires sensitive The data of the sensitivity test is analyzed by the analysis unit to obtain the result of the sensitivity test.
  5. 根据权利要求4所述的一种敏感性试验管理系统,其特征在于:所述分析单元对敏感性试验的影像数据进行识别,通过红肿部位的位置、颜色、面积、高度中的至少一项数据,分析得出敏感性 试验的结果。A sensitivity test management system according to claim 4, characterized in that: the analysis unit identifies the image data of the sensitivity test, and uses at least one data of the position, color, area, and height of the red and swollen part , to analyze the results of the sensitivity test.
  6. 根据权利要求4所述的一种敏感性试验管理系统,其特征在于:所述敏感性试验管理系统根据敏感性试验的结果和患者信息、疾病信息、待测过敏物信息进行评估,给出评估结果。A sensitivity test management system according to claim 4, characterized in that: the sensitivity test management system evaluates according to the results of the sensitivity test and patient information, disease information, and allergen information to be tested, and gives an evaluation result.
  7. 根据权利要求6所述的一种敏感性试验管理系统,其特征在于:所述分析单元根据在不同的患者信息和疾病信息的条件下,待测过敏物在包括安全性、有效性、经济性、适宜性中的至少一项分析项目的不同分析结果,分别设定对应的级别/分值,在进行待测过敏物评估时,能够根据待测过敏物在各分析项目所对应的级别/分值以及设置的待测过敏物评估模型,计算出不同待测过敏物的综合级别/分值。A sensitivity test management system according to claim 6, characterized in that: the analysis unit is based on the conditions of different patient information and disease information, the allergens to be tested include safety, effectiveness, economy According to the different analysis results of at least one of the analysis items in the suitability, the corresponding grades/scores are set respectively. When evaluating the allergens to be tested, it can value and the set test allergen evaluation model to calculate the comprehensive level/score of different test allergens.
  8. 根据权利要求6所述的一种敏感性试验管理系统,其特征在于:所述敏感性试验管理系统还根据待测过敏物评估结果对患者的原应用方案进行优化与调整。应用方案优化与调整的方法可以包括:调整相关待测过敏物使用方案、调整相关待测过敏物、开展相关待测过敏物使用监测或其他治疗方法等至少一种。The sensitivity test management system according to claim 6, characterized in that: the sensitivity test management system also optimizes and adjusts the patient's original application plan according to the evaluation results of the allergens to be tested. The method of optimizing and adjusting the application plan may include: adjusting the use plan of the relevant test allergen, adjusting the relevant test allergen, carrying out the use monitoring of the relevant test allergen or other treatment methods, etc. at least one.
  9. 一种敏感性试验管理方法,其特征在于,所述方法包括:A sensitivity test management method, characterized in that the method comprises:
    步骤1,建立敏感性试验管理数据库,所述敏感性试验管理数据库包括需要做敏感性试验的规则;Step 1, establishing a sensitivity test management database, the sensitivity test management database includes rules that require sensitivity tests;
    步骤2,获取患者信息、疾病信息和待测过敏物信息;Step 2, obtaining patient information, disease information and allergen information to be tested;
    步骤3,根据患者信息、疾病信息、待测过敏物信息和需要做敏感性试验的规则进行分析,评估是否需要做敏感性试验。Step 3: Analyze according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.
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