WO2023155177A1

WO2023155177A1 - Sensitivity test management system and method

Info

Publication number: WO2023155177A1
Application number: PCT/CN2022/076974
Authority: WO
Inventors: 曹庆恒
Original assignee: 曹庆恒
Priority date: 2022-02-18
Filing date: 2022-02-18
Publication date: 2023-08-24
Also published as: CN117121117A

Abstract

A sensitivity test management system and method. The sensitivity test management system comprises: a database unit (11), an information acquisition unit (12), and an analysis unit (13). The sensitivity test management method comprises: establishing a sensitivity test management database (S1); acquiring patient information, disease information, and information of a substance to be tested for allergens (S2); and according to the patient information, the disease information, the information of the substance and a rule requiring a sensitivity test, performing an analysis to evaluate whether a sensitivity test is required (S3). By means of the system and the method, sensitivity test management is carried out from multiple aspects such as the rule requiring the sensitivity test, the quantitative analysis of test results and the analysis of the substance according to the test results, such that the system and method play an enormous role in promoting the high-quality management of sensitivity tests, improving medical quality, preventing anaphylactic reactions, guaranteeing of safety of patients and the like.

Description

A sensitivity test management system and method

technical field

The invention relates to the technical field of intelligent medical information processing, in particular to a sensitivity test management system and method.

Background technique

With the continuous development of science and technology, people's living standards are constantly improving, and the demand for medical quality is also increasing. In the process of people receiving medical services, allergies seriously affect the quality of medical care, and even endanger their lives. Due to the limitations of medical science, the characteristics of the disease itself, hospital management factors, doctors' professional level, drugs and medical devices, and the actual situation of patients themselves, there is a certain probability of allergic risk in the medical process.

The existing sensitivity test is usually carried out before the doctor takes the medicine. In order to prevent the occurrence of allergic reactions, especially the occurrence of severe allergic reactions, it is stipulated that some drugs that are prone to allergic reactions need to be tested for skin sensitivity before use. If the skin test is negative Drugs can be given to patients, but are prohibited if the skin test is positive. Existing sensitivity tests are usually only for specific drugs, and less consideration is given to patients and disease conditions, and the experimental results are mainly judged based on experience, lacking quantitative standards. At the same time, false positives in sensitive tests will affect accurate drug selection, which may lead to medication risks, over-medication and other problems, and may even delay the timely treatment of patients.

Therefore, apply information technology, combine medical and pharmacy professional data and business, establish a set of practical and comprehensive sensitivity test management system and method, from whether sensitivity test needs to be done, quantitative analysis of test results, and based on test Results Management of sensitivity tests in many aspects, such as medication analysis, is conducive to high-quality management of sensitivity tests, and plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.

Contents of the invention

The main purpose of the present invention is to provide a sensitivity test management system and method for the current situation that the existing sensitivity test management is not refined enough, from the assessment of whether the sensitivity test is needed, the quantitative analysis of the experimental results, and the basis Management of sensitivity tests in various aspects, such as drug analysis of experimental results, is conducive to high-quality management of sensitivity tests, and plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.

To achieve the above object, the present invention provides a sensitivity test management system, said system comprising:

The database unit is used to store a sensitivity test management database, and the sensitivity test management database includes rules that require sensitivity tests;

An information acquisition unit, configured to acquire patient information, disease information, and information on allergens to be tested, the allergens to be tested include: at least one of medicine, diet, medical equipment, light, cosmetics, daily necessities, air, and clothing;

The analysis unit is configured to perform analysis according to the patient information, disease information, allergen information to be tested and the rules requiring a sensitivity test to evaluate whether a sensitivity test is required.

A sensitivity test management system as described above, the sensitivity test management database includes the rules of the sensitivity test scheme, and the sensitivity test management system provides a suitable sensitivity test for patients who need a sensitivity test plan.

According to the sensitivity test management system described above, the database unit further stores a patient personal information database, and the patient personal information database includes relevant information of the patient for providing or supplementing the patient information.

A sensitivity test management system as described above, the sensitivity test management database includes rules for analysis of sensitivity test results, the sensitivity test management system obtains the data of the sensitivity test through the information acquisition unit, and The analysis unit analyzes the data of the sensitivity test to obtain the result of the sensitivity test.

A sensitivity test management system as described above, the analysis unit identifies the image data of the sensitivity test, and analyzes at least one of the data of the position, color, area, and height of the red and swollen part to obtain the sensitivity test the result of.

According to the sensitivity test management system as described above, the sensitivity test management system evaluates according to the results of the sensitivity test and patient information, disease information, and allergen information to be tested, and gives the evaluation results.

According to a sensitivity test management system as described above, the analysis unit is based on at least one of safety, effectiveness, economy, and suitability of the allergen to be tested under different conditions of patient information and disease information. For different analysis results of each analysis item, set the corresponding grades/scores respectively. The substance evaluation model is used to calculate the comprehensive grade/score of different allergens to be tested.

According to the above-mentioned sensitivity test management system, the sensitivity test management system also optimizes and adjusts the patient's original application plan according to the evaluation results of the allergens to be tested. The method of optimizing and adjusting the application plan may include: adjusting the use plan of the relevant test allergen, adjusting the relevant test allergen, carrying out the use monitoring of the relevant test allergen or other treatment methods, etc. at least one.

The present invention also provides a sensitivity test management method, the method comprising:

Step 1, establishing a sensitivity test management database, the sensitivity test management database includes rules that require sensitivity tests;

Step 2, obtaining patient information, disease information and allergen information to be tested;

Step 3: Analyze according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.

A sensitivity test management system and method of the present invention, the sensitivity test management system includes: a database unit, an information acquisition unit and an analysis unit. Sensitivity test management methods include: establishing a sensitivity test management database, obtaining patient information, disease information, and test allergen information, and performing analysis based on patient information, disease information, test allergen information, and rules requiring sensitivity tests, Assess the need for sensitivity testing. Through a sensitivity test management system and method of the present invention, sensitivity test management is carried out from various aspects such as rules for sensitivity tests, quantitative analysis of test results, and analysis of allergens to be tested according to test results, which is beneficial High-quality management of sensitivity tests plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.

Description of drawings

Fig. 1 is a block diagram of a susceptibility test management system of the present invention.

Fig. 2 is a flow chart of a sensitivity test management method of the present invention.

Detailed ways

In order to further explain the technical means and effects adopted by the present invention to achieve the intended purpose, the specific implementation of the present invention will be described in detail below in conjunction with the accompanying drawings and examples.

In the present invention, the sensitivity test includes skin (or intradermal) sensitivity test, and may also include other sensitivity tests. Some drugs are prone to allergic reactions during clinical use, such as penicillin, streptomycin, cytochrome C, etc. Common allergic reactions include rash, urticaria, dermatitis, fever, angioedema, asthma, anaphylactic shock, etc. Among them, anaphylactic shock is the most serious and can even lead to death. In order to prevent the occurrence of allergic reactions, especially the occurrence of severe allergic reactions, it is stipulated that some drugs that are prone to allergic reactions need to be tested for skin sensitivity before use. Drugs with negative skin tests can be given to patients, and those with positive skin tests are prohibited. The allergens to be tested may include: drugs, diet, medical equipment, light, cosmetics, daily necessities, air, clothing, etc.

In the present invention, patients refer to the objects analyzed by the sensitivity test management system, which may include: sick people, medical examiners, pregnant women, children, personnel in special positions, subjects, etc., and may also be other groups of people who need to be tested for allergies.

Refer to FIG. 1 for the first embodiment of the present invention. Fig. 1 is a block diagram of a susceptibility test management system of the present invention. As shown in the figure, a sensitivity test management system of the present invention includes:

Database unit 11, is used for storing sensitivity test management database, and described sensitivity test management database includes the rule that needs to do sensitivity test;

An information acquisition unit 12, configured to acquire patient information, disease information and allergen information to be tested;

The analysis unit 13 is configured to perform analysis according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.

First, a sensitivity test management database needs to be established.

In the present invention, the sensitivity test management database may include: rules requiring sensitivity tests, and may also include rules for sensitivity test schemes and rules for analysis of sensitivity test results. Specifically, it can include various related element attributes and their values/ranges/calculation methods/sources/restrictions/exclusions, and the interrelationships/interactions/transformations between various/groups/various element attributes /rule/calculation method.

The rule that requires a sensitivity test is based on a comprehensive judgment of patient information, disease information, and allergen information to be tested. If certain rules are met, a sensitivity test is required. For example: Some drugs require skin tests according to regulations; some drugs require skin tests only under specific circumstances, such as: those who are allergic to thymosin injection need to do skin tests. Since the occurrence of allergic reactions is closely related to the internal allergens of antibiotics and the patient's own allergic constitution, it is necessary to comprehensively consider the information of the patient, the disease, and the allergen to be tested to determine whether a sensitivity test is required, rather than Simply by using the allergens to be tested to determine whether a sensitivity test is required.

The sensitivity test management database and its contents of the present invention are based on various diagnosis and treatment standards, diagnosis and treatment norms, guidelines, industry norms, teaching materials, clinical treatment paths, drug instructions, medical equipment use/operation instructions, medical device instruction manuals, surgical operation specifications , inspection/inspection specifications, formulary, pharmacopoeia, expert consensus, expert experience, meeting minutes and consensus within the medical consortium/hospital/department, papers, monographs, inventions, scientific inferences, experimental reports, experimental reports, data analysis reports, Test reports, test reports, approval documents, relevant regulations, relevant guidance, relevant policies, relevant systems, relevant catalogs, relevant literature, relevant price regulations, relevant price catalogs, relevant bidding results, relevant price policies, relevant insurance payment terms, Relevant insurance payment agreements, relevant bidding results, relevant procurement catalogs, relevant doctors/nurses/examiners/pharmacists/nursing staff/patients/salespersons’ evaluations/test results/monitoring reports/safety reports, other literature, other professional/ Authoritative research results can also be based on methods of evidence-based medicine, or based on probabilistic speculation based on existing data, and can also include databases established from sources such as various weights/grades/ranks that need to be manually set, or It can include databases established based on information reorganization/information analysis/big data analysis, databases established through artificial intelligence deep learning, databases obtained through data mining analysis, and data statistical analysis After the deep learning of artificial intelligence, the rules and indicators set manually, or the relevant information and rules accumulated and refined by clinicians and pharmacists in the process of disease treatment can also be used. The sensitivity test management database can also be a database established by combining the above methods. The database can be updated by version, or it can be updated in real time based on actual data. The sensitivity test management database can be a relational database or a non-relational database; it can be a table database, a graph database, or a knowledge map database; relevant data can be structured data or unstructured data .

In the sensitivity test management database, the rules related to the need for sensitivity test, the rules of the sensitivity test program and the rules of sensitivity test result analysis may include: various use conditions/requirements/attributes/ Numerical values, such as drug manufacturer, specification, dosage form, daily frequency, time interval, time/daily dosage, time/day maximum dosage, method of use, sensitivity, route of administration, site of administration, etc. Also includes: basic patient information, population information, genetic information, disease information, medical history information, medication history information, medical device use history information, contact history, exposure history, operation items, symptoms, indicators, body position, operation objects, Operation methods, operation objectives, physiological development information, marriage and childbirth information, physiological conditions, psychological/intellectual conditions, life/work/study/sports/entertainment information, environmental information, information related to the use of drugs/medical devices/health products/cosmetics, medical treatment Insurance-related information, ability/willingness to pay for medical expenses, medical institution information, medical personnel information, medical devices/consumables/equipment/instruments/drugs/implants required for drugs, drug costs, care, risk assessment, stages, stages, Anesthesia, respiration, hemostasis, infection prevention, pain, first aid measures, index control, preparation and requirements, training, indications/indications, contraindications, related protection and first aid, nutritional support, doctor level and authority, auxiliary software, imaging, etc. Information about various elements.

In the present invention, group information may include specific age, gender, developmental status, marital status, childbearing status, working status, learning status, exercise status, living status, physiological status, psychological status, genetic status, physical status, immune status and other specific population information. Genetic related information includes: genetic information, genetic information variation/change information, genetic defect information, genetic medical history, family medical history and other information. Disease information includes: disease, diagnosis, symptom, symptom type, symptom, index, pulse condition, tongue diagnosis and other information. Medical history information includes medical history, surgical history, radiotherapy history, chemotherapy history, psychotherapy history, physical therapy history, immunotherapy history, gene therapy history, and other information. Medication history information includes: medication history, drug efficacy, adverse drug reactions, drug allergy history, drug tolerance, and other information. Medical device use history information includes: medical device use history, medical device efficacy, medical device adverse reactions, medical device tolerance, etc. Operation items include surgery, inspection, inspection, test, detection, operation, health care, rehabilitation, psychological treatment, radiotherapy, chemotherapy, physical therapy, hyperthermia, phototherapy, magnetic therapy, electrotherapy, cold therapy, electromagnetic therapy, sound therapy, immunotherapy, Gene therapy, weight loss, fitness, plastic surgery, beauty and other projects. Physiological development information includes: growth and development, physiological stage, fertility and other information. Marriage information includes marriage history, birth history, sex life and other information. Physiological conditions include: physical fitness, nutritional status, hearing, vision, taste, smell, touch, breathing, motor coordination, digestion, absorption, excretion, sexual function, etc. and the level of related abilities. Mental/intellectual conditions include: mental illness, emotions, feelings, intelligence, attention, memory, perception, communication skills, expressive skills, etc. Life/work/study/sports/entertainment information includes: diet, work and rest, sleep, work, study, entertainment, sports and other related information. Environmental information includes: microbial distribution, contact population, temperature, humidity, air pressure, season, altitude, air quality, air diffusion conditions, terrain, landform, oxygen content, light, ultraviolet rays, radiation, electromagnetic waves, noise, epidemics, plant information. Medical insurance related information includes medical benefits, medical insurance, commercial insurance, etc. Medical institution information includes medical institution level, specialties, attributes, regions, departments and other information. Medical personnel information includes: age, gender, position, professional title, professional qualifications, professional training, protective measures and other information. Implants include: grafts, cultures, gene carriers, implanted chips, implanted equipment/devices, etc. Nutritional support includes: water, calories, protein, trace elements, sugar, salt, fat, carbohydrates, minerals, amino acids, vitamin testing, content standards, supplementary dosage, etc.

The rules in the sensitivity test management database that require sensitivity tests, the rules of the sensitivity test program and the rules of the analysis of sensitivity test results can be established based on a single allergen to be tested or a classification of allergens to be tested, or It may include sections established for each test allergen group to be used in combination.

In the present invention, the rules of the sensitivity test scheme are the rules of adopting an appropriate sensitivity test scheme according to different patient information, disease information, and allergen information to be tested. The sensitivity test management system provides a suitable sensitivity test plan for patients who need a sensitivity test based on patient information, disease information, information on allergens to be tested, and the rules of the sensitivity test plan.

The rules for the analysis of sensitivity test results are the rules for giving the results of sensitivity tests based on different patient information, disease information, information on allergens to be tested and sensitivity test data. The sensitivity test management system obtains the data of the sensitivity test through the information acquisition unit, and analyzes the data of the sensitivity test through the analysis unit combining patient information, disease information, and allergen information to obtain the result of the sensitivity test.

The sensitivity test management database of the present invention can also include relevant information on allergic reactions of the allergens to be tested, such as: the relationship between the use method/dose/time/frequency/interval of the allergens to be tested and the allergic reaction, the possibility of the allergens to be tested Allergic reactions and the factors that may affect the allergic reactions and the treatment measures after the allergic reactions occur, specifically including: related influencing factors of allergic reactions, symptoms/indicator signals/manifestations/feelings/severity/harm of allergic reactions, allergic reactions Treatment, allergic reaction prevention methods, remedial measures after allergic reaction occurs, etc.

The sensitivity test management database of the present invention can also include information related to allergic reactions and the use monitoring scheme of the allergen to be tested, such as: monitoring the concentration of the allergen to be tested, monitoring related indicators, monitoring related symptoms, monitoring related physiological conditions, etc. Facts related to allergic reactions during or after drug use are obtained and analyzed.

The sensitivity test management database of the present invention can also include: allergy-related information and information related to allergic reaction type/allergic reaction degree grading/allergic reaction impact, wherein the allergic reaction impact can be further divided into allergic reaction impact type and impact level, and specific consequences of the impact. The type of allergic reaction may include: type I (immediate type); type II (cytotoxic type); type III (immune complex type); type IV (delayed type). The type of allergic reaction impact of the allergens to be tested may include: enhancement/weakening of curative effect, shortening/prolongation of onset time, increase/decrease of toxicity, increase/decrease of treatment cost, enhancement/weakening of compliance, etc.; allergic reaction impact level Can be set to ignore, minor, moderate, severe, critical, dangerous, prohibited, etc.

Secondly, the patient information, disease information and allergen information to be tested are acquired through the information acquisition unit 12 .

Patient information can include: basic patient information, genetic related information, family health related information such as family medical history, medical history, allergy history, regional epidemiological history, medication history, operation history, medical device use history, learning situation, work situation, exercise situation, Family situation, living environment, hobbies, compliance, tolerance, medical insurance, and physiology/psychology/study/work/physical fitness/sleep/exercise/emotion/metabolism/vision/hearing/intelligence/attention/diet /immunity/growth and development/memory/fertility status and work and rest time and other information.

Disease information can include: various physiological/mental/study/work/physical fitness/sleep/exercise/emotional/metabolism/vision/hearing/intelligence/attention/appetite/immunity/growth and development/memory/fertility/genetic correlations of the patient Indicators, parameters, states or conditions of information, etc.; information obtained through inquiry, inspection, detection, test, experiment, operation, evaluation, evaluation, and observation of diseases/symptoms/indicators; and patient growth and development/birth/contraception /Assisted reproduction/Psychological needs/Learning needs/Working needs/Sports needs/Entertainment needs/Nutrition needs/calorie needs, etc.; patient's surgery/operation/examination/detection/monitoring/assessment/evaluation/analysis/prediction/physiotherapy /Heat therapy/Phototherapy/Magnet therapy/Electrotherapy/Rehabilitation/Health care/Immunotherapy/Gene therapy and other information; Information about patients' medicines/Medical devices/Health care products/Cosmetics etc.

The information of the allergen to be tested includes: the name, composition, concentration, contact method and other information of the allergen to be tested. For example, if the allergen to be tested is a drug, its information may include: drug generic name, trade name, manufacturer, drug batch number, drug type, drug specification, drug dosage form, route of administration, site of administration, method of use, administration Dosage, medication time, medication interval, medication frequency, medication cycle and other information.

The sources for the information acquisition unit 12 to acquire patient information, disease information, and allergen information to be tested can be: patient-related symptoms, related indicators, feelings, states, physiological function self-reports; patient self-reports on the states and needs of study, work, life, sports, etc. ; Medical orders issued by medical personnel; patient's medical records, electronic medical records, diagnostic reports, examination results, test results, monitoring results, evaluation reports; obtained from the patient's personal information database; through inquiry, examination, detection, test, experiment, operation Information obtained by methods such as evaluation, evaluation, observation, etc.; pre-set time, season, hour, interval, cycle and other information; pre-set ways to monitor changes in various physiological and pathological indicators; patient personal information database, health Archives, family or family member health records, doctor's orders, medical records, drug records, prescriptions, electronic medical records, medical institution information systems, pharmacy/medical device store information systems, medical records, treatment records, evaluation reports, consultation records, investigation records, schedules Records/plans, diet records/plans, medication records/plans, treatment records/plans, exercise records/plans, work records/plans, study records/plans, rehabilitation records/plans, health care records/plans, inspections/checklists, operations Plans/records, health management plans, bills, clinical treatment paths, examination/test results, surgical settings/records, genetic test results, can also be obtained from patient/doctor/nurse/caregiver use/prescription/recommendation records, It can also be composed of various wearable devices, sensors, electronic devices, electronic positioning systems, weather forecast systems, electronic temperature and humidity/air pressure detection equipment, smart speakers, smart home systems, smart monitoring/monitoring systems, smart glasses, smart toilets, smart Ground, smart scales, smart detection/analysis equipment, electronic infusion systems, surgical robots, face recognition analysis, fingerprint recognition, voice recognition, gait recognition, positioning systems, social platforms and other equipment or systems, can also be provided by patients’ life , Study, work, exercise, travel, social interaction, shopping, diet, work and rest, entertainment and other information can be obtained through big data analysis, and can also be obtained by analyzing relevant information such as the patient's race/family/region/age/marriage/birth. The missing information can also be provided or improved by the patient/doctor/nurse/caregiver, or the highly relevant information can be actively prompted to the patient/doctor/nurse/caregiver to observe, monitor, check, inquire, analyze, Confirm and record whether there is a relevant situation or obtain relevant indicators/performance/feeling/symptoms/physiological changes. The correlation is determined by setting or through data analysis. The importance of safety, economy, suitability/comfort/compliance, etc. is graded or sorted, and the information with higher importance can be set as the information that must be completed or the next step cannot be carried out. When obtaining the actual information of the relevant elements of the patient's treatment plan, it is also possible to analyze the relevant medical information issued by specific medical personnel according to the database of medical personnel's personal information, so as to further accurately grasp the actual information of the relevant elements. Evaluation reports include physical, psychological, economic, credit, athletic ability, etc. Intelligent detection/analysis equipment includes: smell, image, sound, pulse condition, X-ray film, CT, nuclear magnetic resonance, ultrasonic examination, brain wave, mass spectrometer, tongue analysis, fundus examination, gastroscope, colonoscopy, catheter, minimally invasive mirror , heart rate, blood oxygen level, blood pressure, blood sugar, blood lipid, body temperature, blood test, urine test, feces test, pulse measurement/analysis equipment, etc.

In the present invention, the database unit 11 may also store a patient personal information database, which includes relevant information of the patient for providing or supplementing the patient information. The patient's personal information database includes relevant information of the patient, including: basic patient information, genetic information, and family health information such as family medical history, medical history, allergy history, regional epidemic history, medication history, surgical history, and medical device use history , study situation, work situation, sports situation, family situation, living environment, hobbies, compliance situation, tolerance situation, medical insurance situation, and physical/psychological/study/work/physical fitness/sleep/exercise/emotion/metabolism/ Information about vision/hearing/intelligence/attention/diet/immunity/growth/development/memory/fertility and work and rest time.

Then, the analysis unit 13 conducts analysis according to the patient information, disease information, allergen information to be tested and the rules requiring a sensitivity test to evaluate whether a sensitivity test is required.

After obtaining the patient information, disease information, and allergen information to be tested, the analysis unit 13 compares the patient information, disease information, and allergen information to be tested with the rules in the sensitivity test management database that require a sensitivity test, and analyzes Determine whether the patient needs to do the analysis results of the sensitivity test.

In the sensitivity test management system of the present invention, the database unit 11 can also store a sensitivity test element attribute dictionary, which is used to process information obtained from different sources, different data structures, different descriptions, and different data standards and the correlation in the database unit. Matching/comparison of information and rules. Sensitivity test element attribute dictionary, which contains at least one of the standard dictionary, corresponding dictionary of different names, and fuzzy matching dictionary of each element attribute related to sensitivity test, including the different names, structures, combinations and Correspondence data and so on. Matching/comparison can be done by using the obtained original information to compare with the dictionaries corresponding to different names of the items in the sensitivity test element attribute dictionary, or by first converting the obtained original information into corresponding standard dictionaries and then matching them with sensitivity test management database, or use fuzzy matching between the obtained original information and the dictionaries of the sensitivity test management database, or a combination of the above methods. The attribute dictionary of sensitivity test elements can be established separately, or it can be included in the sensitivity test management database.

In the present invention, in addition to using the sensitivity test element attribute dictionary for matching, it can also be processed by speech recognition technology, semantic recognition technology, translation of different languages, OCR recognition technology, virtual reality technology, augmented reality technology, gesture recognition technology, etc. The matching/comparison of the obtained information with the relevant information and rules in the database unit.

The sensitivity test management system of the present invention can also provide a suitable sensitivity test plan for patients who need a sensitivity test after evaluating the results of whether a sensitivity test is required. Sensitivity testing protocols may use skin testing or other methods. The skin test site can be selected from the curved side of the forearm, or the skin of the upper arm or back. Specific test methods can use intradermal test, prick test or patch test.

The sensitivity test protocol is an appropriate protocol given based on patient information, disease information, and allergen information to be tested. In the sensitivity test management system of the present invention, the rules of the sensitivity test scheme can also include the criteria for selecting the sensitivity test scheme and common schemes in various situations. The relevant standards and common schemes can be manually set by experts, or can be After obtaining a large number of examples, conduct data collection, evaluate whether there are common characteristics, and use various related statistical methods, big data monitoring and other methods to establish the combination of elements with common characteristics, and can also be based on evidence-based medicine. Or based on the probability speculation of existing data, it can also include the establishment of various weights/various levels/various rankings that need to be manually set, and can also include establishment based on information reorganization/information analysis/big data analysis, It can also include those established through deep learning of artificial intelligence, or obtained through data mining and analysis, or manually set through statistical analysis of data/deep learning of artificial intelligence, or through It can be established by clinicians and pharmacists through continuous accumulation and refinement in the process of disease diagnosis and treatment, or it can be established through a combination of the above methods, and can be continuously accumulated and optimized during use.

The sensitivity test management system of the present invention can also obtain the data of the sensitivity test through the information acquisition unit 12, and analyze the data of the sensitivity test in combination with the rules of the sensitivity test result analysis through the analysis unit 13, and obtain the sensitivity test result. result.

The information acquiring unit 12 acquires the data of the sensitivity test, which may include: indicators of various sensitivity tests, skin images, position/color/area/height of changes such as skin redness and swelling, etc.

The analysis unit 13 analyzes the data of the sensitivity test, and can adopt a quantitative method to formulate certain standards, and obtain accurate results through precise analysis of the indicators and image data of the sensitivity test, so as to avoid relying on the doctor's personal experience. Performing the analysis results in incorrect results. For example: the image data of the sensitivity test can be identified, and at least one of the position, color, area, and height of the red and swollen part can be analyzed to obtain the result of the sensitivity test.

The rules for analysis of sensitivity test results may include analysis criteria for sensitivity test results. The analysis standard of the sensitivity test results can be manually set by experts, or after obtaining a large number of examples, data collection can be carried out to evaluate whether there are common characteristics, and for the combination of elements with common characteristics, various relevant statistical methods, The establishment of methods such as big data monitoring can also be based on methods of evidence-based medicine, or based on probability speculation based on existing data, and can also include sources such as various weights/various levels/various sorts that need to be manually set. It can also include those established based on information reorganization/information analysis/big data analysis, or those established through artificial intelligence deep learning, or those obtained through data mining analysis, or those obtained through data statistical analysis/manual After intelligent deep learning, it must be manually set, or it can be established through the continuous accumulation and refinement of clinicians and pharmacists in the process of disease diagnosis and treatment, or it can be established through a combination of the above methods, and can be used during use Continuous accumulation and optimization.

The sensitivity test management system of the present invention can also evaluate according to the results of the sensitivity test and patient information, disease information, and allergen information to be tested, and give the evaluation results.

The analysis unit 13 can respectively set corresponding When evaluating the allergens to be tested, the levels/scores of the allergens to be tested can be calculated according to the corresponding levels/scores of the allergens to be tested in each analysis item and the set evaluation model of the allergens to be tested. Comprehensive level/point value. Used for test allergen assessments, including comparisons of different test allergens or test allergen regimens.

In the present invention, the allergens to be tested can be evaluated from the safety, effectiveness, economy, and suitability of the application of the allergens to be tested, and whether the application plan of the allergens to be tested is suitable for the patient can be analyzed. For example: if a patient has a severe allergic reaction to a certain drug, which may be life-threatening, the drug must not be used; and if a drug has only a mild allergic reaction, but the therapeutic effect and price of the drug are excellent, then the drug can be used Consider using. The safety analysis items of the evaluation of the allergens to be tested can include: allergic risk, the severity of allergic reactions, the safety of allergy tests, etc.; the effectiveness analysis items can include: the impact on curative effect and severity, etc.; the economic analysis items It can include: treatment cost and amount, etc.; the suitability analysis items can include: the impact of compliance, etc. When evaluating the allergens to be tested, according to the business needs of different business units, an evaluation model of the allergens to be tested composed of the analysis results of each analysis item can be set up, so that the relationship between each analysis item and the evaluation of the allergens to be tested can be obtained. Comprehensive assessment results. The business units here can be divided into business scenarios based on various dimensions and combinations such as administration, medical institutions, departments, doctors, users, drugs, and diseases.

The evaluation model of the allergens to be tested can be manually set and established by experts, or after obtaining a large number of examples, data collection can be carried out to evaluate whether there are common characteristics. For the combination of elements with common characteristics, various relevant statistical methods, Establish methods such as big data monitoring. The establishment of the model can be based on the method of evidence-based medicine, or based on the probability speculation of existing data, and can also include the establishment of various weights/various levels/various rankings that need to be manually set, and can also include information-based Reorganization/information analysis/big data analysis can also include those established through artificial intelligence deep learning, data mining and analysis, and data statistical analysis/artificial intelligence deep learning. It is manually set, or it can be established through the continuous accumulation and refinement of clinicians and pharmacists in the process of disease diagnosis and treatment. The parameters of the model can be manually set by experts, or obtained through data statistics/analysis, or obtained through information reorganization/big data analysis, or obtained through artificial intelligence deep learning/optimization, and can be Continuously accumulate and optimize during use.

In the present invention, the comprehensive grade/score value of the test allergen assessment can be used to give the test allergen assessment result, or to compare the test allergen or the test allergen schemes with each other. A certain threshold can be set in advance. When evaluating the allergen to be tested, the comprehensive level/score of different allergens to be tested or the scheme of the allergen to be tested is calculated, compared with the preset threshold, and the to-be-tested allergen is given. The results of the allergy assessment. Thresholds of different levels can be preset, for example: reminder level, prohibition level, warning level, suggestion level, recommendation level, report level, etc.

The sensitivity test management system of the present invention can also optimize and adjust the application plan of the patient's original allergen to be tested according to the evaluation result of the allergen to be tested. The method for optimizing and adjusting the specific application plan may include: adjusting the use plan of the relevant test allergen, adjusting the relevant test allergen, carrying out the use monitoring of the relevant test allergen or other treatment methods, etc. at least one.

Take the allergen to be tested as a drug as an example. Adjustment of the relevant drug usage plan includes: adjustment of the relevant drug administration time plan, adjustment of the relevant drug use method plan, etc. Specifically, it includes: at least one of adjusting the frequency of administration, adjusting the time interval between medications, adjusting the route of administration, adjusting the site of administration, and adjusting the method of use, etc., or a combination of two or more.

The above-mentioned adjustment of the administration time of relevant drugs refers to reducing or eliminating the influence of allergic reactions by adjusting the administration frequency or time of administration of the drugs. Comprehensively analyze the range of possible adjustments in the use time of related drugs based on factors such as pharmacokinetics, disease characteristics, and user compliance. The specific adjustment method is: according to the relationship between the impact of drug allergic reaction and the time interval of drug use, as well as the reasonable drug use time range of each drug that may have a certain risk of allergic reaction, it can be obtained that the relevant drug is in line with the reasonable drug use time range. The drug administration time plan that minimizes the impact of allergic reactions is the optimal drug use time plan. The drug use time optimization scheme may be one or a collection of multiple time schemes. For example, if the user is allergic to the new product C produced by the joint action of drug A and drug B in the body, the allergic reaction can be eliminated by adjusting the administration time of A or B, prolonging the interval between the two drugs, and avoiding the generation of product C. Impact.

Adjusting the usage method of relevant drugs mentioned above refers to reducing or eliminating the impact of allergic reactions by adjusting the route of administration, the site of administration, and the method of use. Comprehensively analyze the range of possible adjustments of relevant drug usage methods through pharmacokinetics, disease characteristics, user compliance and other factors. For example, some external medicines will cause allergic reactions when used on the face, but there is no allergic phenomenon when used on other parts of the body. You can reduce or eliminate the impact of allergic reactions by adjusting the administration site and avoiding use on sensitive skin parts.

Adjustment of relevant drugs includes at least one of the following: reducing drugs, increasing drugs, changing drugs, etc. on the basis of the original drug regimen. Specifically, it includes: excluding drugs that may have a certain risk of allergic reaction from the drug regimen, replacing drugs that may have a certain risk of allergic reaction with other drugs that have the same clinical effect but have a lower risk of allergic reaction. On this basis, new drugs are added to reduce the risk of original allergic reactions.

The reduction of drugs mentioned above refers to reducing or eliminating the impact of allergic reactions by stopping one or several drugs in the original drug regimen. The choice of drug discontinuation may include whether the drug is the preferred/first-line treatment for a certain indication, whether the drug is used for a long time, etc. For example: patients with type 2 diabetes mellitus combined with metformin and sulfonylurea hypoglycemic drugs, assuming that the blood sugar control of the patient has reached the target with metformin alone before adding sulfonylureas, and the patient has a history of allergy to sulfonylureas, it can be stopped by stopping the sulfonylureas. Eliminates the risk of allergic reactions.

The above-mentioned replacement of drugs refers to reducing or eliminating the impact of allergic reactions by replacing one or several drugs in the original drug regimen. Changing medicines includes changing dosage forms, changing specifications, changing manufacturers, changing drug names, etc. Whether the drug in the original drug regimen can be replaced, factors can include whether the drug is the preferred/first-line treatment for a certain indication, whether the drug has an alternative, whether the current business unit has an alternative to the drug, whether the drug is long-term Medication, etc. For example, patients with type 2 diabetes who have a history of allergy to sulfonamides may experience cross-allergies when taking sulfonylureas. The sulfonylureas can be replaced by other oral hypoglycemic agents such as biguanides and glucosidase inhibitors.

Adding drugs as mentioned above refers to reducing or eliminating the impact of allergic reactions by adding new drugs on the basis of the original drug regimen. Add drugs to prevent or treat allergic reactions that may be caused by the original drug regimen, or interact with drugs in the original drug regimen to produce new clinical effects or reduce drug toxicity in the original drug regimen, so as to reduce or eliminate allergic reactions in the original drug regimen Impact. For example, the incidence of hypersensitivity reactions among users receiving paclitaxel injection is as high as 30% to 41%. Pretreatment with glucocorticoids plus H1 and H2 receptor antagonists can be performed before infusion of paclitaxel injection to prevent hypersensitivity. reaction occurs.

The above-mentioned relevant medication monitoring scheme includes at least one of: monitoring the blood drug concentration of relevant drugs, monitoring related indicators, monitoring related symptoms, and monitoring related physiological conditions. For example, if a patient may be allergic to a certain drug, but there is no replacement plan, the relevant indicators and symptoms of the patient can be closely monitored. Once allergic indications appear, the drug should be stopped immediately.

The above-mentioned other treatment methods include: at least one of surgery, physical therapy, traditional Chinese medicine therapy, psychotherapy, rehabilitation therapy, and comprehensive health management.

The method of optimizing the drug regimen can also be a combination of the above methods, that is, adjusting the time regimen of relevant drug administration, adjusting the regimen of relevant drug usage, reducing drugs, increasing drugs, changing drugs, carrying out relevant drug monitoring, using other treatment methods, etc. Two or more of them are used at the same time.

In the present invention, whether a sensitivity test is required, the results of the sensitivity test, and the evaluation results of the allergens to be tested given by the sensitivity test management system can be used to assist in reminding, warning, restricting, prohibiting, assisting, and guiding patients/ Physician/Nurse/Caregiver for treatment. It can also be used for patient/doctor/nurse/caregiver and referral/management/guidance/counseling post or secondary referral/management/guidance/counseling center discussion and data basis for advanced post reply/auto-reply. It can also be used as a basis for professional level evaluation/professional normative evaluation/performance evaluation/performance appraisal of doctors/nurses/caregivers and other personnel afterwards. It can also be used as a basis for sales or refusal of sales by unmanned vending machines/e-commerce/pharmacies/medical institutions. It can also be connected with various information systems/information platforms/various unmanned vending machines/smart wearable devices/smart home devices/smart medical devices/medical devices/remote control medical devices, as related operations or processes triggered by systems or related devices Configurable control items, such as vending, smart reminder, smart start, smart shutdown, etc. It can also be used as a medical insurance management agency/medical insurance company/health administrative department/credit evaluation agency/grade review agency/judicial agency to evaluate, assess, supervise, enforce, manage, and refer to medical institutions/pharmacies/medical equipment retail stores. It can also be used as a basis for guardians/family doctors/family pharmacists/health managers/family care management patients' treatment/rehabilitation/health care/examination, and can also be used for intelligent health management systems/disease management systems for patients' health Management/disease management, can also be used for scientific research institutions/researchers/production companies/sales companies/using organizations/purchasing organizations/patients/doctors/nurses/pharmacists/caregivers/salespersons and other related objects selection/evaluation/design/development/ The data basis for sales can also be used for data when medical insurance management agencies/medical insurance companies/price management departments/health administrative departments/medical institutions formulate surgery-related policies/regulations/payment scope/payment ratio/payment amount/use scope, etc. in accordance with. It is also possible to set the feedback objects and applications of the above analysis items and their analysis results. According to the needs of patients, the analysis results of each analysis item are fed back to different departments and different positions, and the processing authority and process of each department and position are set. As well as the processing time limit and processing requirements of each link, various corresponding analysis result reports can also be generated according to management requirements. The application of sensitivity test management results can be in the mode of prior recommendation, mid-event review, or post-event evaluation. According to the management results of the sensitivity test, the normative evaluation report issued is provided to the medical administration management personnel, medical insurance institutions, medical insurance management personnel, and circulation field management personnel to prompt various violations and illegal acts that may exist, in order to further standardize diagnosis and treatment process support.

In the present invention, various analysis results, assessments, reports and other output information of the sensitivity test management system can be manually completed by professionals according to the sensitivity test management database and various data, or manually completed with the support of the system, It can also be completed automatically by the system, by artificial intelligence, or by a combination of system/artificial intelligence and manual completion. The form of application/output of relevant sensitivity test management and analysis results can be reminders, notifications, reports, reports, system authority restrictions, system process restrictions, control of related systems/equipment/files/authorities, etc.; it can also be the provision of relevant interfaces It can also be implemented by connecting with other management systems; it can also be an application that provides analysis results and the user manually implements the relevant analysis results.

In the present invention, the identification, confirmation, login, and electronic signature of patients, medical personnel, and related roles in the sensitivity test management system, as well as the storage, transmission, and application of personal information, medical information, and various analysis results can be done through Various methods are used for encryption to prevent related identities/permissions from being stolen or information leaked. The encryption algorithms include symmetric encryption algorithms and/or asymmetric encryption algorithms, such as: encryption algorithms for large integer decomposition problems, encryption algorithms for discrete logarithm problems, and elliptic curve encryption algorithms, such as blockchain technology, etc. The encryption hardware can Using keys, dongles, encrypted hard disks, etc., can also be combined with user equipment hardware, network addresses, etc. for encryption, and the above methods can also be combined for encryption.

In the present invention, the data transmission mode of the sensitivity test management system can be data line mode, wired network, wireless transmission mode, radio frequency identification mode, magnetic card reading and writing mode, mobile hard disk mode, NFC mode, bar code mode, two-dimensional code mode wait. Wireless transmission methods include: infrared, bluetooth, wifi, microwave, visible light wave, telecommunications wireless network, ultrasonic/sound wave, radio and other methods.

In the present invention, the susceptibility test management system can be used as a stand-alone machine, or can be used by users with access-type external hardware such as mobile hard disks, boxes, cards, etc., or can be installed on local servers to support local users, or can be installed on The private cloud server supports the use of private cloud users, and can also be installed on the Internet to provide services to Internet users.

Refer to FIG. 2 for the second embodiment of the present invention. Fig. 2 is a method flowchart of a sensitivity test management method of the present invention. As shown in the figure, the sensitivity test management method of the present invention includes:

The sensitivity test management method of the present invention may also include:

Step 4, obtaining the data of the sensitivity test and analyzing the data of the sensitivity test to obtain the result of the sensitivity test.

Step 5: Evaluate the allergen to be tested according to the results of the sensitivity test, patient information, disease information, and allergen to be tested, and give the evaluation result.

The sensitive test management method of the present invention corresponds to the technical features of the sensitive test management system of the present invention one by one, and reference may be made to the description of the aforementioned sensitive test management system, which will not be repeated here.

In summary, a sensitivity test management system and method of the present invention, the sensitivity test management system includes: a database unit, an information acquisition unit and an analysis unit. Sensitivity test management methods include: establishing a sensitivity test management database, obtaining patient information, disease information, and test allergen information, and performing analysis based on patient information, disease information, test allergen information, and rules requiring sensitivity tests, Assess the need for sensitivity testing. Through a sensitivity test management system and method of the present invention, sensitivity test management is carried out from various aspects such as rules for sensitivity tests, quantitative analysis of test results, and analysis of allergens to be tested according to test results, which is beneficial High-quality management of sensitivity tests plays a huge role in improving medical quality, preventing allergic reactions, and ensuring patient safety.

The specific embodiments described above have further described the purpose, technical solutions and beneficial effects of the present invention in detail. It should be understood that the above descriptions are only specific embodiments of the present invention and are not intended to limit the scope of the present invention. Protection scope, within the spirit and principles of the present invention, any modification, equivalent replacement, improvement, etc., shall be included in the protection scope of the present invention.

Claims

A sensitivity test management system, characterized in that the system includes:

The database unit is used to store a sensitivity test management database, and the sensitivity test management database includes rules that require sensitivity tests;

An information acquisition unit, configured to acquire patient information, disease information, and information on allergens to be tested, the allergens to be tested include: at least one of medicine, diet, medical equipment, light, cosmetics, daily necessities, air, and clothing;

The analysis unit is configured to perform analysis according to the patient information, disease information, allergen information to be tested and the rules requiring a sensitivity test to evaluate whether a sensitivity test is required.
A sensitivity test management system according to claim 1, characterized in that: the sensitivity test management database includes rules for sensitivity test schemes, and the sensitivity test management system for patients who need to do sensitivity tests, A suitable sensitivity test plan is given.
A sensitivity test management system according to claim 1, characterized in that: said database unit also stores a patient personal information database, said patient personal information database includes relevant information of the patient, for providing or supplementing patient information. information.
A sensitivity test management system according to claim 1, characterized in that: said sensitivity test management database includes rules for analysis of sensitivity test results, and said sensitivity test management system acquires sensitive The data of the sensitivity test is analyzed by the analysis unit to obtain the result of the sensitivity test.
A sensitivity test management system according to claim 4, characterized in that: the analysis unit identifies the image data of the sensitivity test, and uses at least one data of the position, color, area, and height of the red and swollen part , to analyze the results of the sensitivity test.
A sensitivity test management system according to claim 4, characterized in that: the sensitivity test management system evaluates according to the results of the sensitivity test and patient information, disease information, and allergen information to be tested, and gives an evaluation result.
A sensitivity test management system according to claim 6, characterized in that: the analysis unit is based on the conditions of different patient information and disease information, the allergens to be tested include safety, effectiveness, economy According to the different analysis results of at least one of the analysis items in the suitability, the corresponding grades/scores are set respectively. When evaluating the allergens to be tested, it can value and the set test allergen evaluation model to calculate the comprehensive level/score of different test allergens.
The sensitivity test management system according to claim 6, characterized in that: the sensitivity test management system also optimizes and adjusts the patient's original application plan according to the evaluation results of the allergens to be tested. The method of optimizing and adjusting the application plan may include: adjusting the use plan of the relevant test allergen, adjusting the relevant test allergen, carrying out the use monitoring of the relevant test allergen or other treatment methods, etc. at least one.
A sensitivity test management method, characterized in that the method comprises:

Step 1, establishing a sensitivity test management database, the sensitivity test management database includes rules that require sensitivity tests;

Step 2, obtaining patient information, disease information and allergen information to be tested;

Step 3: Analyze according to the patient information, disease information, allergen information to be tested and the rules requiring sensitivity testing to evaluate whether sensitivity testing is required.