WO2023124390A1 - 程控设备和植入式神经刺激系统 - Google Patents

程控设备和植入式神经刺激系统 Download PDF

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Publication number
WO2023124390A1
WO2023124390A1 PCT/CN2022/125078 CN2022125078W WO2023124390A1 WO 2023124390 A1 WO2023124390 A1 WO 2023124390A1 CN 2022125078 W CN2022125078 W CN 2022125078W WO 2023124390 A1 WO2023124390 A1 WO 2023124390A1
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path
sliding
preset
program
parameter
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PCT/CN2022/125078
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English (en)
French (fr)
Inventor
马艳
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苏州景昱医疗器械有限公司
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Publication of WO2023124390A1 publication Critical patent/WO2023124390A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators

Definitions

  • the present application relates to the technical field of implantable medical devices, in particular to a program-controlled device and an implanted nerve stimulation system.
  • the implantable neurostimulation system mainly includes a stimulator implanted in the body and a program-controlled device outside the body.
  • Neuromodulation technology mainly uses stereotaxic surgery to implant electrodes in specific structures (i.e., target points) in the body, and the stimulator implanted in the patient sends electrical pulses to the target points through the electrodes to regulate the electrical activity of the corresponding neural structures and networks. Its function can improve symptoms and relieve pain.
  • the purpose of this application is to provide a program-controlled device and an implanted nerve stimulation system, which greatly reduces the user's operation steps, makes parameter value setting faster and more convenient, and improves the user's experience.
  • the present application provides a program-controlled device, which is applied to an implantable nerve stimulation system, and the implantable nerve stimulation system includes the program-controlled device arranged outside the patient's body and the stimulation device implanted in the patient's body. device;
  • the programmed device is communicatively connected to the stimulator, the programmed device comprising:
  • a touch screen configured to receive user operations
  • a communication module configured to enable data interaction between the program-controlled device and the stimulator
  • a controller the controller is electrically connected to the touch screen and the communication module respectively, the controller is configured to:
  • a control instruction is generated and sent to the stimulator, so that the stimulator generates electrical stimulation according to the control instruction and applies the electrical stimulation to the internal tissue of the patient.
  • the beneficial effects of this technical solution are: Generally speaking, when setting parameter values, the existing program-controlled equipment needs to input specific values or gradually adjust through multiple button operations, and the efficiency of parameter value setting is low.
  • the program-controlled equipment of the present application can support user's Sliding operation, the user can set the parameter value by sliding, which greatly reduces the user's operation steps, makes the parameter value setting faster and more convenient, and improves the user experience.
  • the controller is further configured to obtain the configuration parameter value of the target parameter in the following manner:
  • the reference path corresponding to the sliding path is obtained, and the reference path is a preset Assuming a part of the circular path and the path direction of the reference path is determined by the path direction of the sliding path, the preset circular path is in the preset sliding area;
  • the configuration parameter value of the target parameter is acquired based on the reference path.
  • the beneficial effect of this technical solution is: use two-stage detection process to judge whether it is a misoperation, only when it is judged that the sliding operation is not a misoperation, the configuration parameter value is obtained, when the first stage detects the position of each track point of the sliding path When both are in the preset sliding area, instead of directly calculating the configuration parameter value, it enters the second stage of detection.
  • the two-stage detection process can play a double insurance role, avoiding users from setting unreasonable parameter values due to misoperation, and ensuring the safety of patients.
  • the first stage it is detected whether the positions of the track points of the sliding path are all in the preset sliding area, and when it is detected that the positions of the track points of the sliding path are all in the preset sliding area, it indicates that The user may have the intention to configure parameters, and enter the second stage at this time; in the second stage, based on the starting point, end point and path direction of the sliding path, the reference path corresponding to the sliding path is obtained, the similarity between the sliding path and the reference path is obtained, and the detection Whether the similarity is not less than a preset similarity threshold, and when the similarity is not less than a preset similarity threshold, it can be determined that the sliding operation is not a misoperation.
  • the controller is further configured to:
  • the valid starting point range including the current parameter value of the target parameter corresponding to the position point on the touch screen
  • the starting point of the sliding path is not within the effective starting point range, no operation is performed, or the user is prompted to re-operate, or an area corresponding to the effective starting point range is displayed on the touch screen in a blinking state.
  • the beneficial effect of this technical solution is: to detect whether the starting point of the sliding path is within the effective starting point range, if the starting point of the sliding path is not within the effective starting point range, it indicates that the sliding operation may be misoperation by the user. Indirectly remind the user that the sliding operation is invalid by not responding after the operation, or directly prompt the user to re-operate, or display the area corresponding to the effective starting point range on the touch screen in a blinking state, any of the above processing methods can serve as a reminder to the user The effect of this sliding operation is invalid, and the degree of intelligence is relatively high.
  • the controller is further configured to obtain the reference path in the following manner:
  • a path between the start point and the end point of the reference path is intercepted from the preset circular path as the reference path.
  • the beneficial effect of this technical solution is: the point on the preset circular path closest to the starting point of the sliding path is used as the starting point of the reference path, and the point on the preset circular path closest to the end point of the sliding path is used as the end point of the reference path, Intercept the path between the start point and the end point of the reference path along the sliding path in the preset circular path as the reference path.
  • the reference path thus obtained is more suitable for the sliding path, and it is easier to obtain the corresponding configuration parameter values according to the reference path.
  • Reasonable can truly reflect the user's intention when configuring parameters.
  • the controller is further configured to obtain the similarity in the following manner:
  • the beneficial effect of this technical solution is that the preset deep learning model can be trained according to the similarity training data to obtain the similarity model, and the corresponding similarity can be automatically generated in real time only by inputting the sliding path and the reference path into the similarity model , a high degree of intelligence.
  • a preset deep learning model can be obtained.
  • Establish the functional relationship from input to output Although the functional relationship between input and output cannot be found 100%, it can approach the actual correlation as much as possible.
  • the similarity model trained by this can output the corresponding similarity in real time. And the reliability of the output result is high.
  • the controller is further configured to acquire the preset similarity threshold in the following manner:
  • a similarity threshold corresponding to the patient's disease type is acquired as the preset similarity threshold.
  • the beneficial effect of this technical solution is that patients with different disease types may have different hand control abilities. Compared with patients with strong hand control, Parkinson's patients with poor hand control have the same sliding path when sliding. The deviation of the circular path may be large, and the similarity may be low. For patients with different disease types, different preset similarity thresholds are used, so that the program-controlled equipment can support patients with poor hand control to perform sliding operations, greatly reducing It reduces the operating difficulty for patients when using program-controlled equipment.
  • the controller is further configured to obtain the configuration parameter value of the target parameter in the following manner:
  • a configuration parameter value of the target parameter is determined based on the ratio of the length of the reference path to the preset circular path and the range of the target parameter.
  • the beneficial effect of this technical solution is that: based on the ratio of the length of the reference path to the preset circular path and the range of the target parameter, the parameter value of the target parameter can be adjusted steplessly, and the configuration parameter value of the target parameter can be within the range of the target parameter Any value of , to meet the needs of practical applications.
  • the preset circular path is provided with at least one scale, and the controller is further configured to obtain the configuration parameter value of the target parameter in the following manner:
  • the configuration parameter value of the target parameter is determined.
  • the beneficial effect of this technical solution is that: based on the setting value of the target parameter corresponding to the closest scale of the reference path, the parameter value of the target parameter can be adjusted to obtain the configuration parameter value of the target parameter, and the configuration parameter value of the target parameter can be multiple One of the set values of the target parameters corresponding to the scales can meet the needs of practical applications.
  • the controller obtains the range of the target parameter in the following manner:
  • the beneficial effect of this technical solution is that: the configuration process of each parameter of the stimulator is not isolated, and the configuration parameter value of each parameter is associated with the range of other parameters, so that when setting the parameters, only a relatively reasonable It is completed within the range, avoiding the user from setting unreasonable parameter values and ensuring the safety of patients.
  • the preset circular path is sequentially provided with N scales along its clockwise direction, and the set value of the target parameter corresponding to the kth scale corresponds to the k-1th scale
  • the difference between the set value of the target parameter is smaller than the difference between the set value of the target parameter corresponding to the k+1th scale and the set value of the target parameter corresponding to the kth scale value
  • N is an integer greater than 2
  • k is an integer greater than 1 and less than N.
  • the beneficial effect of this technical solution is that: along the clockwise direction of the preset circular path itself, the difference between the set values of the target parameters corresponding to two adjacent scales becomes larger and larger, so that the user slides clockwise During the process, the magnitude of the set value corresponding to the track point changes gradually, which further speeds up the efficiency of parameter value setting.
  • the controller is further configured to:
  • the beneficial effect of this technical solution is: when the position of any track point of the sliding path is not in the preset sliding area, it indicates that the sliding operation may be caused by a user's misoperation, and it is judged that the sliding operation is invalid.
  • Any of the above processing methods can play a role.
  • the function of reminding the user that the sliding operation is invalid this time has a high degree of intelligence.
  • the controller is further configured to:
  • the beneficial effect of this technical solution is that: when the similarity is less than the preset similarity threshold, it indicates that the sliding operation may be caused by the user’s mistaken touch, and it is judged that the sliding operation is invalid. At this time, no operation can be performed. Indirectly remind the user that the sliding operation is invalid in a non-responsive manner, or prompt the user to re-operate, or display the preset circular path on the touch screen in a blinking state. Any of the above processing methods can remind the user that the sliding operation is invalid The role of intelligence is higher.
  • the target parameter is any one of a voltage pulse width parameter, an amplitude parameter, and a frequency parameter.
  • the target parameter can be any one of the pulse width parameter, amplitude parameter and frequency parameter of the voltage, so that the program-controlled device can control the stimulator to apply corresponding electrical stimulation to the patient based on the configuration parameter value of the target parameter , to meet the needs of practical applications.
  • the patient's disease type includes one or more of epilepsy, tremor, Parkinson's disease, depression, obsessive-compulsive disorder, Alzheimer's disease, and drug addiction.
  • the beneficial effect of the technical solution is that the stimulators in patients with different types of diseases can be controlled by using the program-controlled equipment, and the scope of application is wide.
  • the present application provides an implantable neurostimulation system, the implanted neurostimulation system includes the programmable device arranged outside the patient's body and a stimulator implanted in the patient's body;
  • the programmed device is communicatively connected to the stimulator, the programmed device comprising:
  • a touch screen configured to receive user operations
  • a communication module configured to enable data interaction between the program-controlled device and the stimulator
  • a controller the controller is electrically connected to the touch screen and the communication module respectively, the controller is configured to:
  • a control instruction is generated and sent to the stimulator, so that the stimulator generates the electrical stimulation according to the control instruction.
  • the implantable nerve stimulation system of the present application can support the user's sliding operation, and the user can set the parameter value by sliding, which greatly reduces the user's operation steps and makes the parameter value setting faster and more convenient , to improve user experience.
  • FIG. 1 is a schematic flowchart of a method for controlling a program-controlled device provided in an embodiment of the present application
  • FIG. 2 is a schematic flow diagram of obtaining configuration parameter values of target parameters provided by an embodiment of the present application
  • Fig. 3 is a schematic diagram of a display interface of a touch screen provided by an embodiment of the present application.
  • Fig. 4 is a schematic flowchart of another method for controlling a program-controlled device provided in an embodiment of the present application.
  • FIG. 5 is a schematic flow diagram of obtaining a reference path provided by an embodiment of the present application.
  • FIG. 6 is a schematic flow chart of obtaining similarity provided by an embodiment of the present application.
  • Fig. 7 is a schematic flow chart of obtaining a preset similarity threshold provided by an embodiment of the present application.
  • FIG. 8 is a schematic flowchart of another method for obtaining configuration parameter values of target parameters provided by the embodiment of the present application.
  • FIG. 9 is a schematic flowchart of another method for obtaining configuration parameter values of target parameters provided by the embodiment of the present application.
  • FIG. 10 is a schematic flowchart of a part of a method for controlling a program-controlled device provided in an embodiment of the present application.
  • Fig. 11 is a partial flowchart of another method for controlling a program-controlled device provided in an embodiment of the present application.
  • Fig. 12 is a structural block diagram of a program-controlled device provided by an embodiment of the present application.
  • Fig. 13 is a structural block diagram of an implantable nerve stimulation system provided by an embodiment of the present application.
  • At least one means one or more, and “multiple” means two or more.
  • “And/or” describes the association relationship of associated objects, indicating that there may be three types of relationships, for example, A and/or B, which can mean: A exists alone, A and B exist at the same time, and B exists alone, where A, B can be singular or plural.
  • the character “/” generally indicates that the contextual objects are an “or” relationship.
  • “At least one of the following" or similar expressions refer to any combination of these items, including any combination of single or plural items.
  • At least one item (piece) of a, b or c can represent: a, b, c, a and b, a and c, b and c or a and b and c, wherein a, b and c can be It can be single or multiple. It is worth noting that "at least one item (item)" can also be interpreted as “one item (item) or multiple items (item)”.
  • words such as “exemplary” or “for example” are used to mean an example, illustration or illustration. Any embodiment or design described herein as “exemplary” or “for example” is not to be construed as preferred or advantageous over other embodiments or designs. Rather, the use of words such as “exemplary” or “such as” is intended to present related concepts in a concrete manner.
  • An implantable neurostimulator system (an implanted medical system) mainly includes a stimulator implanted in a patient (ie, an implanted neurostimulator) and a program-controlled device placed outside the patient's body.
  • the program-controlled device may include an in vitro controller, and the program-controlled device may also be an in vitro controller.
  • the existing neuromodulation technology mainly uses stereotaxic surgery to implant electrodes in specific structures (i.e., targets) in the body, and the stimulator implanted in the patient sends electrical pulses to the targets through the electrodes to regulate the corresponding neural structures and networks. Electrical activity and its function, thereby improving symptoms and relieving pain.
  • the stimulator can be an implantable electrical nerve stimulation device, an implantable cardiac electrical stimulation system (also known as a cardiac pacemaker), an implantable drug infusion device (Implantable Drug Delivery System, referred to as I DDS) and a wire. Any one of the switching devices.
  • Implantable electrical nerve stimulation devices are, for example, Deep Brain Stimulation (DBS), Implantable Cortical Nerve Stimulation (CNS), Implantable Spinal Cord Stimulation , referred to as SCS), implanted sacral nerve stimulation system (Sacral Nerve Stimulation, referred to as SNS), implanted vagus nerve stimulation system (Vagus Nerve Stimulation, referred to as VNS), etc.
  • the stimulator can include IPG, extension wires and electrode wires.
  • IPG implantable pulse generator, implantable pulse generator
  • IPG is set in the patient's body, receives the program control instructions sent by the program control device, and provides controllable stimulation to the tissues in the body relying on sealed batteries and circuits.
  • Electrical stimulation energy through implanted extension leads and electrode leads, delivers one or two controlled, specific electrical stimuli to specific areas of tissue in the body.
  • the extension wire is used in conjunction with the IPG as a transmission medium for the electrical stimulation signal, and transmits the electrical stimulation signal generated by the IPG to the electrode wire.
  • Electrode leads deliver electrical stimulation to specific areas of tissue in the body through multiple electrode contacts.
  • the stimulator is provided with one or more electrode wires on one side or both sides, and a plurality of electrode contacts are arranged on the electrode wires, and the electrode contacts can be arranged uniformly or non-uniformly in the circumferential direction of the electrode wires.
  • the electrode contacts may be arranged in an array of 4 rows and 3 columns (a total of 12 electrode contacts) in the circumferential direction of the electrode wire.
  • Electrode contacts may include stimulation electrode contacts and/or collection electrode contacts.
  • the electrode contacts can be in the shape of, for example, a sheet, a ring, or a dot.
  • the stimulated body tissue may be the patient's brain tissue, and the stimulated site may be a specific part of the brain tissue.
  • the stimulated site is generally different, the number of stimulation contacts (single source or multi-source) used, one or more channels (single-channel or multi-channel) specific electrical stimulation signals
  • the application and stimulus parameter data are also different.
  • the embodiment of the present application does not limit the applicable disease types, which may be the applicable disease types for deep brain stimulation (DBS), spinal cord stimulation (SCS), pelvic stimulation, gastric stimulation, peripheral nerve stimulation, and functional electrical stimulation.
  • DBS disorders that DBS can be used to treat or manage include, but are not limited to: spasticity disorders (e.g., epilepsy), pain, migraine, psychiatric disorders (e.g., major depressive disorder (MDD)), bipolar disorder, anxiety disorders, Post-traumatic stress disorder, hypodepression, obsessive-compulsive disorder (OCD), conduct disorder, mood disorder, memory disorder, mental status disorder, mobility disorder (eg, essential tremor or Parkinson's disease), Huntington's disease, Al Alzheimer's disease, drug addiction, autism, or other neurological or psychiatric conditions and impairments.
  • spasticity disorders e.g., epilepsy
  • pain migraine
  • psychiatric disorders e.g., major depressive disorder (MDD)
  • bipolar disorder e.g., anxiety disorders, Post-traumatic stress disorder, hypodepression, obsessive-compulsive disorder (OCD)
  • OCD obsessive-compulsive disorder
  • conduct disorder mood disorder
  • the program-controlled device when the program-controlled device and the stimulator establish a program-controlled connection, can be used to adjust the stimulation parameters of the stimulator (different stimulation parameters correspond to different electrical stimulation signals), and the stimulator can also be used to sense the deep brain of the patient.
  • the bioelectric activity of the stimulator can be used to collect the electrophysiological signal, and the stimulation parameters of the electrical stimulation signal of the stimulator can be adjusted continuously through the collected electrophysiological signal.
  • Stimulation parameters can include: frequency (for example, the number of electrical stimulation pulse signals per unit time 1s, unit is Hz), pulse width (duration of each pulse, unit is ⁇ s), amplitude (generally expressed by voltage, that is, The intensity of each pulse, the unit is V), timing (for example, it can be continuous or triggered), stimulation mode (including one or more of current mode, voltage mode, timed stimulation mode and cycle stimulation mode), doctor's control upper limit One or more of upper and lower limits (range adjustable by doctors) and upper and lower limits of patient control (range adjustable by patients).
  • frequency for example, the number of electrical stimulation pulse signals per unit time 1s, unit is Hz
  • pulse width duration of each pulse, unit is ⁇ s
  • amplitude generally expressed by voltage, that is, The intensity of each pulse, the unit is V
  • timing for example, it can be continuous or triggered
  • stimulation mode including one or more of current mode, voltage mode, timed stimulation mode and cycle stimulation mode
  • doctor's control upper limit One or more of upper and lower limits (range adjustable
  • various stimulation parameters of the stimulator can be adjusted in current mode or voltage mode.
  • the program-controlled device may be a doctor-programmed device (ie, a program-controlled device used by a doctor) or a patient-programmed device (ie, a program-controlled device used by a patient).
  • the doctor's program-controlled device can be, for example, a tablet computer, a notebook computer, a desktop computer, a mobile phone and other smart terminal devices equipped with program-controlled software.
  • the patient program-controlled device can be, for example, smart terminal devices such as tablet computers, notebook computers, desktop computers, and mobile phones equipped with program-controlled software, and the patient program-controlled device can also be other electronic devices with program-controlled functions (such as chargers with program-controlled functions, data collection device).
  • the embodiment of the present application does not limit the data interaction between the doctor's program-controlled device and the stimulator.
  • the doctor's program-controlled device can perform data interaction with the stimulator through the server and the patient's program-controlled device.
  • the doctor’s program-controlled device can interact with the stimulator through the patient’s program-controlled device, and the doctor’s program-controlled device can also directly interact with the stimulator.
  • the patient programmable device may include a host (communicating with the server) and a slave (communicating with the stimulator), the host and slave being communicatively connected.
  • the doctor's program-controlled equipment can exchange data with the server through the 3G/4G/5G network
  • the server can exchange data with the host through the 3G/4G/5G network
  • the host can exchange data with the slave through the Bluetooth protocol/WIFI protocol/USB protocol.
  • the sub-machine can exchange data with the stimulator through the 401MHz-406MHz working frequency band/2.4GHz-2.48GHz working frequency band, and the doctor's program-controlled equipment can directly exchange data with the stimulator through the 401MHz-406MHz working frequency band/2.4GHz-2.48GHz working frequency band interact.
  • an embodiment of the present application provides a control method for a program-controlled device, which is applied to an implantable neurostimulation system, and the implanted neurostimulation system includes the program-controlled device arranged outside the patient's the stimulator in the patient;
  • the programmed device is communicatively connected to the stimulator, the programmed device comprising:
  • a touch screen configured to receive user operations
  • a communication module configured to enable data interaction between the program-controlled device and the stimulator
  • the method includes steps S101 to S102.
  • Step S101 using the touch screen to receive a sliding operation, and obtain the configuration parameter value of the target parameter in response to the sliding operation;
  • Step S102 Based on the configuration parameter value of the target parameter, generate a control instruction and send it to the stimulator, so that the stimulator generates electrical stimulation according to the control instruction and applies the electrical stimulation to the internal tissue of the patient. Stimulate.
  • the stimulator can be an implantable electrical nerve stimulation device, an implantable cardiac electrical stimulation system (also known as a cardiac pacemaker), an implantable drug infusion device (Implantable Drug Delivery System, referred to as IDDS) and a lead transfer device any of the.
  • Implantable electrical nerve stimulation devices are, for example, Deep Brain Stimulation (DBS), Implantable Cortical Nerve Stimulation (CNS), Implantable Spinal Cord Stimulation , referred to as SCS), implanted sacral nerve stimulation system (Sacral Nerve Stimulation, referred to as SNS), implanted vagus nerve stimulation system (Vagus Nerve Stimulation, referred to as VNS) and so on.
  • DBS Deep Brain Stimulation
  • CNS Implantable Cortical Nerve Stimulation
  • SCS Implantable Spinal Cord Stimulation
  • SNS implanted sacral nerve stimulation system
  • Vagus Nerve Stimulation referred to as VNS
  • the stimulator is set in the patient's body for providing electrical stimulation
  • Program-controlled devices may include, but are not limited to: smart phones (such as Android phones, iOS phones, etc.), tablet computers, portable personal computers, mobile Internet devices (Mobile Internet Devices, MID) and other devices, which are not limited in the embodiments of this application.
  • a programmable device may include a physician-programmed device and/or a patient-programmed device.
  • the patient programming device is equipped for the patient, and the patient can use the patient programming device to adjust the parameters of the corresponding stimulator by himself.
  • the corresponding preset adjustment range can be set based on the patient's disease information, and the patient can only adjust the corresponding stimulator parameters within the corresponding preset adjustment range.
  • the doctor's program-controlled device is equipped for doctors.
  • a doctor's program-controlled device can use the communication module to perform data interaction with the stimulators of multiple patients.
  • the communication module may include a wired communication module and/or a wireless communication module.
  • the wired communication module may include one or more of an optical fiber communication unit, a coaxial cable communication unit, an open wire communication unit, a waveguide communication unit, and a photoelectric communication unit; the wireless communication module may include a 4G communication unit, a 5G communication unit, a WIFI communication unit, One or more of near field communication unit, WiGig communication unit, Bluetooth communication unit, ZigBee communication unit, microwave communication unit, satellite communication unit and atmospheric laser communication unit.
  • the wired communication module is relatively stable, with high reliability and high transmission rate; the wireless communication module has a longer communication distance and is not limited by wires, and has certain mobility. It can communicate through a wireless connection in a mobile state, and the cost is relatively low. Low.
  • the touch screen may include any one of a resistive touch screen, a capacitive touch screen, and a surface acoustic wave screen.
  • the target parameter may be any one of a voltage pulse width parameter, an amplitude parameter, and a frequency parameter.
  • the target parameter may be any one of a current pulse width parameter, an amplitude parameter, and a frequency parameter.
  • the target parameter can be any one of the pulse width parameter, amplitude parameter and frequency parameter, so that the program-controlled device can control the stimulator to apply corresponding electrical stimulation to the patient based on the configuration parameter value of the target parameter, meeting the needs of practical applications.
  • the step S101 may include steps S201 to S204.
  • Step S201 Obtain a sliding path corresponding to the target parameter in response to the sliding operation
  • Step S202 When it is detected that the position of each track point of the sliding path is in the preset sliding area, based on the starting point, the ending point and the path direction of the sliding path, obtain the reference path corresponding to the sliding path, the reference path
  • the path is a part of a preset circular path and the path direction of the reference path is determined by the path direction of the sliding path, the preset circular path is in the preset sliding area;
  • Step S203 Obtain the similarity between the sliding path and the reference path
  • Step S204 when the similarity is not less than a preset similarity threshold, based on the reference path, acquire the configuration parameter value of the target parameter.
  • a two-stage detection process is used to determine whether it is a misoperation. Only when it is judged that the sliding operation is not a misoperation can the configuration parameter value be obtained.
  • the first stage detects that the position of each track point of the sliding path is in the preset sliding In the area, instead of directly calculating the configuration parameter value, it enters the second stage of detection.
  • the detected similarity is not less than the preset similarity threshold, it is determined that the sliding operation is not a misoperation, and then the configuration parameter value is obtained.
  • the detection process of each stage can play the role of double insurance, preventing users from setting unreasonable parameter values due to misoperation, and ensuring the safety of patients' lives.
  • the first stage it is detected whether the positions of the track points of the sliding path are all in the preset sliding area, and when it is detected that the positions of the track points of the sliding path are all in the preset sliding area, it indicates that The user may have the intention to configure parameters, and enter the second stage at this time; in the second stage, based on the starting point, end point and path direction of the sliding path, the reference path corresponding to the sliding path is obtained, the similarity between the sliding path and the reference path is obtained, and the detection Whether the similarity is not less than a preset similarity threshold, and when the similarity is not less than a preset similarity threshold, it can be determined that the sliding operation is not a misoperation.
  • the shape of the preset sliding area may be a ring concentric with the preset circular path.
  • the present application does not limit the length of the sliding path.
  • the user can slide less than one circle along the preset sliding area of the touch screen, or can slide multiple circles along the preset sliding area of the touch screen (the total number of circles may not be an integer).
  • the reference path may be less than one preset circular path, may be one preset circular path, or may be a non-integer number of preset circular paths (for example, 1.5, 3.5, etc.).
  • the reference path is, for example, 0.3 circles of the preset circular path;
  • the reference path is, for example, 1 circle of the preset circle path; Set a circular path.
  • the method may further include step S205 to step S207.
  • Step S205 Before step S202, detect whether the starting point of the sliding path is within a valid starting point range, and the valid starting point range includes the position point on the touch screen corresponding to the current parameter value of the target parameter;
  • Step S206 If the starting point of the sliding path is within the effective starting point range, then detecting whether the positions of the track points of the sliding path are all within the preset sliding area;
  • Step S207 If the starting point of the sliding path is not within the effective starting point range, no operation is performed, or the user is prompted to re-operate, or an area corresponding to the valid starting point range is displayed on the touch screen in a blinking state.
  • the starting point of the sliding path is within the valid starting point range. If the starting point of the sliding path is not within the valid starting point range, it indicates that the sliding operation may be misoperation by the user. At this time, you can do nothing. If there is no response after the sliding operation Indirectly remind the user that the sliding operation is invalid, or directly prompt the user to re-operate, or display the area corresponding to the effective starting point range in a blinking state on the touch screen. Any of the above processing methods can remind the user that the sliding operation is invalid. The role of intelligence is higher.
  • the effective starting point range is, for example, a circle centered on the point on the touch screen corresponding to the current parameter value of the target parameter, and the radius is a circle with a preset size;
  • the location point of is a square with the preset size as the side length.
  • the preset size is, for example, 8mm, 10mm or 20mm.
  • the step S202 may include steps S301 to S303.
  • Step S301 Find a point on the preset circular path that is closest to the starting point of the sliding path as the starting point of the reference path;
  • Step S302 Find a point on the preset circular path that is closest to the end point of the sliding path as the end point of the reference path;
  • Step S303 Based on the path direction of the sliding path, intercept the path between the start point and the end point of the reference path from the preset circular path as the reference path.
  • the point on the preset circular path closest to the starting point of the sliding path is used as the starting point of the reference path
  • the point on the preset circular path closest to the end point of the sliding path is used as the end point of the reference path to intercept the preset circular path
  • the path direction along the sliding path from the start point to the end point of the reference path is used as the reference path.
  • the reference path thus obtained is more suitable for the sliding path. It is more reasonable to obtain the corresponding configuration parameter values according to the reference path, which can truly reflect The intent of the user when configuring parameters.
  • the step S203 may include steps S401 to S403.
  • Step S401 Obtain a plurality of similarity training data, each of which includes a sample sliding path used for training, a sample reference path, and the marked similarity between them;
  • Step S402 using multiple similarity training data to train a preset deep learning model to obtain a similarity model
  • Step S403 Input the sliding path and the reference path into the similarity model to obtain the similarity.
  • the preset deep learning model can be trained according to the similarity training data to obtain the similarity model. Just input the sliding path and the reference path into the similarity model, and the corresponding similarity can be automatically generated in real time, and the degree of intelligence is relatively high. high.
  • a preset deep learning model can be obtained. Through the learning and tuning of the preset deep learning model, Establish the functional relationship from input to output. Although the functional relationship between input and output cannot be found 100%, it can approach the actual correlation as much as possible.
  • the similarity model trained by this can output the corresponding similarity in real time. And the reliability of the output result is high.
  • the preset similarity threshold may be obtained through steps S501 to S502.
  • Step S501 Obtain the first correspondence between disease types and similarity thresholds
  • Step S502 Based on the patient's disease type and the first correspondence, obtain a similarity threshold corresponding to the patient's disease type as the preset similarity threshold.
  • the ability of hand control of patients with different disease types may be different.
  • Parkinson's patients with poor hand control can deviate from the preset circular path when sliding It may be larger, but the similarity may be lower.
  • different preset similarity thresholds are used, so that the program-controlled device can support patients with poor hand control to perform sliding operations, which greatly reduces the patient's use of the program-controlled device. Difficulty in operating the device.
  • the similarity threshold corresponding to Parkinson's disease is 60%
  • the similarity threshold corresponding to depression is 80%
  • the similarity threshold corresponding to drug addiction is 85%.
  • the patient Zhang San is a Parkinson's patient
  • the preset similarity threshold of Zhang San is 60%.
  • the lowest similarity threshold among all disease types of the patient may be used as the patient's preset similarity threshold.
  • the program-controlled device of this application is not limited to the applicable disease types, and the disease types include but are not limited to: spasticity disease (for example, epilepsy), pain, migraine, mental illness (for example, major depressive disorder (MDD)), bipolar disorder , anxiety disorders, post-traumatic stress disorder, hypodepression, obsessive-compulsive disorder (OCD), behavioral disorders, mood disorders, memory disorders, mental status disorders, mobility disorders (eg, tremors or Parkinson's disease), Huntington's disease, Al Alzheimer's disease, drug addiction disorder, or other neurological or psychiatric conditions and impairments.
  • spasticity disease for example, epilepsy
  • pain migraine
  • mental illness for example, major depressive disorder (MDD)
  • bipolar disorder e.g., anxiety disorders, post-traumatic stress disorder, hypodepression, obsessive-compulsive disorder (OCD)
  • OCD obsessive-compulsive disorder
  • behavioral disorders eg, tremors or Parkinson's disease
  • the patient's disease type includes one or more of epilepsy, tremor, Parkinson's disease, depression, obsessive-compulsive disorder, Alzheimer's disease, and drug addiction.
  • the stimulators in patients with different disease types can be controlled by using the program-controlled equipment, and the scope of application is wide.
  • the step S204 may include steps S601 to S602.
  • Step S601 Obtain the range of the target parameter corresponding to the preset circular path
  • Step S602 Determine the configuration parameter value of the target parameter based on the ratio of the length of the reference path to the preset circular path and the range of the target parameter.
  • the range of the target parameter is used to indicate the first set value and the second set value of the target parameter.
  • the measuring range refers to the measuring range of the measuring tool, and the measuring range is determined by the graduation value and the maximum measuring value of the measuring tool.
  • the range of the meter is the value of the difference between the upper and lower limits of the nominal range of the meter. If the measurement lower limit of the instrument is zero, the maximum value of the physical quantity that can be measured is equal to its range.
  • the parameter value of the target parameter can be adjusted steplessly, and the configuration parameter value of the target parameter can be any value within the range of the target parameter, satisfying requirements in practical applications.
  • the step S602 may include:
  • determining the configuration parameter value of the target parameter based on the ratio of the length of the reference path to the preset circular path, the path direction of the reference path, the current parameter value of the target parameter, and the range of the target parameter .
  • the first set value of the target parameter can be the minimum set value of the target parameter
  • the second set value of the target parameter can be the maximum set value of the target parameter.
  • configuration parameter values are in the range between the minimum setpoint and the maximum setpoint.
  • the target parameter is the voltage pulse width parameter of the stimulator
  • the range of the voltage pulse width parameter is 0-960 ⁇ s
  • the first setting value of the voltage pulse width parameter is 0 ⁇ s
  • the second setting value is 960 ⁇ s.
  • the first set value and the second set value of the target parameter can both be at the minimum set value of the target parameter and the range between the maximum set value.
  • the above method can support the user to slide multiple circles along the preset sliding area of the touch screen.
  • the adjustment range of the parameter value of the target parameter is large, if the user is only allowed to slide one circle, it is inconvenient for the user to perform fine control within the scope of one circle. It is very easy to cause the parameter value to be set too high or too low, but the program-controlled device of the present application can support the user to slide multiple times along the preset sliding area of the touch screen, which is convenient for the user to make fine adjustments.
  • the target parameter is the voltage amplitude parameter of the stimulator
  • the first setting value of the voltage amplitude parameter is 0V
  • the second setting value is 0.6V.
  • the reference path is 3.5 preset circular paths, the ratio of the length of the reference path to the preset circular path is 3.5, the path direction of the reference path is counterclockwise, and the current parameter value of the voltage amplitude parameter is 2.35V, then the voltage amplitude parameter
  • the configuration parameter value of 2.35V-3.5 ⁇ (0.6-0)V 0.25V.
  • the preset circular path is provided with at least one scale, and the step S204 may include steps S701 to S702.
  • Step S701 Obtain the range of the target parameter corresponding to the preset circular path and the set value of the target parameter corresponding to each scale of the preset circular path;
  • Step S702 Determine the configuration parameter value of the target parameter based on the set value of the target parameter corresponding to the closest scale of the reference path.
  • the parameter value of the target parameter can be adjusted to obtain the configuration parameter value of the target parameter.
  • the configuration parameter value of the target parameter can be the target corresponding to multiple scales.
  • One of the set values of the parameters meets the requirements in practical applications.
  • the target parameter is the voltage pulse width parameter.
  • the preset circular path is set with 20 scales. 120 ⁇ s...960 ⁇ s, the closest scale to the end point of the reference path is the fourth scale, then the configuration parameter value of the voltage pulse width parameter is 80 ⁇ s.
  • the step S601 or the step S701 obtains the range of the target parameter in the following manner:
  • the target parameter is One of the parameters of the stimulator, the parameters of the stimulator include the amplitude parameter of the constant current, the frequency parameter of the constant current, the amplitude parameter of the constant voltage, the pulse width parameter of the constant voltage, and the frequency parameter of the constant voltage multiple.
  • each parameter of the stimulator is not isolated, and the configuration parameter value of each parameter is associated with the range of other parameters, so that when setting parameters, it can only be completed within a relatively reasonable range, avoiding Users set unreasonable parameter values to ensure the safety of patients.
  • the preset circular path is provided with a plurality of scales
  • the reference path corresponding to the sliding path is no more than one preset circular path
  • the range of the target parameter is used to indicate the minimum setting of the target parameter. fixed value and maximum set value.
  • the range of the target parameter includes an operable part and an inoperable part
  • the method further includes: displaying on the touch screen in a first state the corresponding part of the operable part of the range of the target parameter scale, and, in the second state, the touch screen displays a scale other than the scale corresponding to the inoperable part of the range of the target parameter;
  • the corresponding target parameter is the voltage frequency parameter
  • the associated parameter corresponding to the voltage frequency parameter is the voltage amplitude parameter
  • the configuration parameter value of the voltage amplitude parameter is 0.2V
  • the range of the voltage frequency parameter is 40Hz ⁇ 120Hz
  • the configuration parameter value of the voltage amplitude parameter is 0.3V
  • the range of the voltage frequency parameter can be 60Hz-160Hz.
  • the preset circular path has 8 scales.
  • the corresponding setting values of these 8 scales are 20Hz, 40Hz, 60Hz, 80Hz, 100Hz, 120Hz, 140Hz and 160Hz.
  • the scale corresponding to the operable part of the range of the voltage frequency parameter includes the second scale to the sixth scale.
  • the 2nd to 6th scales are displayed in green, and the 1st, 7th, and 8th scales are displayed in red or gray.
  • the scale range corresponding to the green state is operable, and the scale range corresponding to the red or gray state is not operable.
  • the preset circular path is sequentially provided with N scales along its clockwise direction, and the set value of the target parameter corresponding to the kth scale corresponds to the k-1th scale
  • the difference between the set value of the target parameter and the difference between the set value of the target parameter corresponding to the k+1th scale and the set value of the target parameter corresponding to the kth scale The values are the same, N is an integer greater than 2, and k is an integer greater than 1 and less than N.
  • the controller of the program-controlled device can use the touch screen to display the parameter values of the N scales.
  • the target parameter is the voltage amplitude parameter
  • the preset circular path is provided with 255 scales in sequence along the path direction of the sliding path, and the difference between the set values of the voltage amplitude parameter corresponding to two adjacent scales is The value is a fixed value of 0.05V, and the setting values of the voltage amplitude parameters corresponding to these 255 scales are 0.05V, 0.1V, 0.15V, 0.2V, 0.25V, 0.3V...12.75V.
  • N scales correspond to the set values of the marked parameters to form an arithmetic sequence, which conforms to the user's operating habits.
  • the preset circular path is sequentially provided with N scales along its clockwise direction, the set value of the target parameter corresponding to the kth scale and the target corresponding to the k-1th scale The difference between the set values of the parameters is different from the difference between the set value of the target parameter corresponding to the k+1th scale and the set value of the target parameter corresponding to the kth scale.
  • the target parameter is the voltage frequency parameter
  • the preset circular path is provided with 8 scales in sequence along the path direction of the sliding path, and the difference between the set values of the voltage frequency parameter corresponding to two adjacent scales is not the same.
  • the setting values of the voltage and frequency parameters corresponding to these 8 scales are 20Hz, 60Hz, 100Hz, 200Hz, 210Hz, 230Hz, 240Hz and 245Hz.
  • the setting value of the target parameter corresponding to any scale can be flexibly set according to the needs of practical applications, and the application range is wide.
  • the preset circular path is sequentially provided with N scales along its clockwise direction, the set value of the target parameter corresponding to the kth scale and the target corresponding to the k-1th scale The difference between the set values of the parameters is smaller than the difference between the set value of the target parameter corresponding to the k+1th scale and the set value of the target parameter corresponding to the kth scale.
  • the method may further include step S208.
  • Step S208 When it is detected that the position of any track point of the sliding path is not in the preset sliding area, no operation is performed, or the user is prompted to re-operate, or the touch screen displays the Default sliding area.
  • the method may further include step S209.
  • Step S209 When the similarity is less than the preset similarity threshold, no operation is performed, or the user is prompted to re-operate, or the preset circular path is displayed on the touch screen in a blinking state.
  • the similarity is less than the preset similarity threshold, it indicates that the sliding operation may be caused by the user's mistaken touch, and it is judged that the sliding operation is invalid. At this time, you can do nothing and perform the sliding operation without any response. Indirectly remind the user that the sliding operation is invalid, or remind the user to re-operate, or display the preset circular path on the touch screen in a blinking state. Through any of the above processing methods, it can remind the user that the sliding operation is invalid. Smart Higher degree.
  • the present application also provides a program-controlled device 100 , whose specific implementation mode is consistent with the implementation mode and achieved technical effect described in the above-mentioned control method embodiment, and part of the content will not be repeated here.
  • the program-controlled device 100 is applied to an implantable neurostimulation system, and the implanted neurostimulation system includes the program-controlled device 100 arranged outside the patient's body and a stimulator implanted in the patient's body;
  • the program-controlled device 100 is communicably connected to the stimulator, and the program-controlled device 100 includes:
  • the touch screen 101 is configured to receive user operations
  • a communication module 102 the communication module 102 is configured to realize data interaction between the program-controlled device 100 and the stimulator;
  • a controller 103, the controller 103 is electrically connected to the touch screen 101 and the communication module 102 respectively, and the controller 103 is configured to:
  • a control instruction is generated and sent to the stimulator, so that the stimulator generates electrical stimulation according to the control instruction and applies the electrical stimulation to the internal tissue of the patient.
  • the controller 103 may include at least one memory, at least one processor, and a bus connecting different platform systems.
  • the memory may include one or more of random access memory (RAM), read only memory (ROM) and cache memory.
  • RAM random access memory
  • ROM read only memory
  • cache memory stores a computer program, which is executable by the processor.
  • a bus may represent one or more of several types of bus structures, including a memory bus, a peripheral bus, an accelerated graphics port, or a local bus using any of a variety of bus structures.
  • controller 103 is further configured to obtain the configuration parameter value of the target parameter in the following manner:
  • the reference path corresponding to the sliding path is obtained, and the reference path is a preset Assuming a part of the circular path and the path direction of the reference path is determined by the path direction of the sliding path, the preset circular path is in the preset sliding area;
  • the configuration parameter value of the target parameter is acquired based on the reference path.
  • controller 103 is further configured to:
  • the valid starting point range including the current parameter value of the target parameter Corresponding position points on the touch screen 101;
  • the starting point of the sliding path is not within the effective starting point range, no operation is performed, or the user is prompted to re-operate, or the area corresponding to the valid starting point range is displayed on the touch screen 101 in a blinking state.
  • controller 103 is further configured to obtain the reference path in the following manner:
  • a path between the start point and the end point of the reference path is intercepted from the preset circular path as the reference path.
  • controller 103 is further configured to obtain the similarity in the following manner:
  • controller 103 is further configured to acquire the preset similarity threshold in the following manner:
  • a similarity threshold corresponding to the patient's disease type is acquired as the preset similarity threshold.
  • controller 103 is further configured to obtain the configuration parameter value of the target parameter in the following manner:
  • the configuration parameter value of the target parameter is determined based on the ratio of the length of the reference path to the preset circular path and the range of the target parameter.
  • the preset circular path is provided with at least one scale, and the controller 103 is further configured to obtain the configuration parameter value of the target parameter in the following manner:
  • the configuration parameter value of the target parameter is determined.
  • the controller 103 acquires the range of the target parameter corresponding to the preset circular path in the following manner:
  • the preset circular path is sequentially provided with N scales along its clockwise direction, and the set value of the target parameter corresponding to the kth scale corresponds to the k-1th scale
  • the difference between the set value of the target parameter is smaller than the difference between the set value of the target parameter corresponding to the k+1th scale and the set value of the target parameter corresponding to the kth scale value
  • N is an integer greater than 2
  • k is an integer greater than 1 and less than N.
  • controller 103 is further configured to:
  • controller 103 is further configured to:
  • the target parameter is any one of a voltage pulse width parameter, an amplitude parameter, and a frequency parameter.
  • the patient's disease type includes one or more of epilepsy, tremor, Parkinson's disease, depression, obsessive-compulsive disorder, Alzheimer's disease, and drug addiction.
  • the present application also provides an implantable nerve stimulation system 300 , whose specific implementation mode is consistent with the implementation mode and achieved technical effect described in the above-mentioned control method embodiment, and part of the content will not be repeated here.
  • the implantable nerve stimulation system 300 includes the programmable device 100 arranged outside the patient's body and a stimulator implanted in the patient's body;
  • the stimulator is configured to generate electrical stimulation and apply the electrical stimulation to internal tissue of the patient;
  • the program-controlled device 100 is communicably connected to the stimulator, and the program-controlled device 100 includes:
  • the touch screen 101 is configured to receive user operations
  • a communication module 102 the communication module 102 is configured to realize data interaction between the program-controlled device 100 and the stimulator;
  • a controller 103, the controller 103 is electrically connected to the touch screen 101 and the communication module 102 respectively, and the controller 103 is configured to:
  • a control instruction is generated and sent to the stimulator, so that the stimulator generates the electrical stimulation according to the control instruction.
  • the implantable nerve stimulation system 300 of the present application can support the user's sliding operation, and the user can set the parameter value by sliding, which greatly reduces the user's operation steps, makes the parameter value setting faster and more convenient, and improves the user's Use experience.
  • connection When an element is referred to as being “on” or “over”, “connected to” or “coupled to” another element, the element may be directly on, directly connected to, or Or directly bonded to the other component, or intermediate components may be present. However, when an element is referred to as being “directly on,” “directly connected to,” or “directly coupled to” another element, there are no intervening elements present. To this end, the term “connected” may refer to a physical connection, an electrical connection, etc., with or without intervening components.

Abstract

本申请提供了一种程控设备和植入式神经刺激系统，所述程控设备包括：触摸屏，所述触摸屏被配置成接收用户的操作；通信模块，所述通信模块被配置成实现所述程控设备与刺激器之间的数据交互；控制器，所述控制器分别与所述触摸屏和所述通信模块电连接，所述控制器被配置成：利用所述触摸屏接收滑动操作，响应于所述滑动操作，获取目标参数的配置参数值；基于所述目标参数的配置参数值，生成控制指令并发送至所述刺激器，以使所述刺激器根据所述控制指令生成电刺激并向所述患者的体内组织施加所述电刺激。用户可以通过滑动的方式设置参数值，大大减少了用户的操作步骤，使得参数值设置更为快速便捷，提升用户的使用体验。

Description

程控设备和植入式神经刺激系统
本申请要求于2021年12月27日提交的申请号为202111615735.1的中国专利的优先权，上述中国专利通过全文引用的形式并入。
技术领域
本申请涉及植入式医疗设备技术领域，尤其涉及程控设备和植入式神经刺激系统。
背景技术
植入式神经刺激系统主要包括植入体内的刺激器以及体外的程控设备。神经调控技术主要是通过立体定向手术在体内特定结构(即靶点)植入电极，并由植入患者体内的刺激器经电极向靶点发放电脉冲，调控相应神经结构和网络的电活动及其功能，从而改善症状、缓解病痛。
现有的程控设备在设置参数值时需要输入具体数值或者通过多次按键操作逐步调节，参数值设置效率低下，用户的使用体验较差。
发明内容
本申请的目的在于提供程控设备和植入式神经刺激系统，大大减少了用户的操作步骤，使得参数值设置更为快速便捷，提升用户的使用体验。
本申请的目的采用以下技术方案实现：
第一方面，本申请提供了一种程控设备，应用于植入式神经刺激系统，所述植入式神经刺激系统包括设置于患者体外的所述程控设备和植入于所述患者体内的刺激器；
所述程控设备与所述刺激器可通信地连接，所述程控设备包括：
触摸屏，所述触摸屏被配置成接收用户的操作；
通信模块，所述通信模块被配置成实现所述程控设备与所述刺激器之间的数据交互；
控制器，所述控制器分别与所述触摸屏和所述通信模块电连接，所述控制器被配置成：
利用所述触摸屏接收滑动操作，响应于所述滑动操作，获取目标参数的配置 参数值；
基于所述目标参数的配置参数值，生成控制指令并发送至所述刺激器，以使所述刺激器根据所述控制指令生成电刺激并向所述患者的体内组织施加所述电刺激。
该技术方案的有益效果在于：一般而言，现有的程控设备在设置参数值时需要输入具体数值或者通过多次按键操作逐步调节，参数值设置效率低下，本申请的程控设备可以支持用户的滑动操作，用户可以通过滑动的方式设置参数值，大大减少了用户的操作步骤，使得参数值设置更为快速便捷，提升用户的使用体验。
在一种可能的实现方式中，所述控制器被进一步配置成采用如下方式获取所述目标参数的配置参数值：
响应于所述滑动操作，获取所述目标参数对应的滑动路径；
当检测到所述滑动路径的各轨迹点的位置均处于预设滑动区域时，基于所述滑动路径的起点、终点和路径方向，获取所述滑动路径对应的参考路径，所述参考路径是预设圆周路径的一部分且所述参考路径的路径方向由所述滑动路径的路径方向确定，所述预设圆周路径处于所述预设滑动区域；
获取所述滑动路径和所述参考路径的相似度；
当所述相似度不小于预设相似度阈值时，基于所述参考路径，获取所述目标参数的配置参数值。
该技术方案的有益效果在于：使用两个阶段的检测过程来判断是否为误操作，只有判断滑动操作不是误操作时才获取配置参数值，当第一阶段检测到滑动路径的各轨迹点的位置均处于预设滑动区域时，并非直接进行配置参数值的计算，而是进入第二阶段的检测，当检测到相似度不小于预设相似度阈值时，才确定滑动操作不是误操作，进而获取配置参数值，两个阶段的检测过程可以起到双重保险的作用，避免用户因为误操作而设置不合理的参数值，保障患者的生命安全。
具体而言，在第一阶段，检测所述滑动路径的各轨迹点的位置是否均处于预设滑动区域，当检测到所述滑动路径的各轨迹点的位置均处于预设滑动区域时，表明用户可能有配置参数的意图，这时进入第二阶段；在第二阶段，基于滑动路径的起点、终点和路径方向，获取滑动路径对应的参考路径，获取滑动路径和参考路径的相似度，检测相似度是否不小于预设相似度阈值，当相似度不小于预设 相似度阈值时，可以确定滑动操作并非误操作。
在一种可能的实现方式中，所述控制器还被配置成：
在检测所述滑动路径的各轨迹点的位置是否均处于所述预设滑动区域之前，检测所述滑动路径的起点是否处于有效起点范围，所述有效起点范围包括所述目标参数的当前参数值对应的所述触摸屏上的位置点；
如果所述滑动路径的起点处于所述有效起点范围，则检测所述滑动路径的各轨迹点的位置是否均处于所述预设滑动区域；
如果所述滑动路径的起点不处于所述有效起点范围，则不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述有效起点范围对应的区域。
该技术方案的有益效果在于：检测滑动路径的起点是否处于有效起点范围，若滑动路径的起点不处于有效起点范围，表明滑动操作可能为用户误操作，此时，可以不做任何操作，通过滑动操作后没有反应的方式进行间接提示用户滑动操作无效，或者，直接提示用户重新操作，或者，在触摸屏以闪烁的状态显示有效起点范围对应的区域，以上任意一种处理方式均可以起到提示用户本次滑动操作无效的作用，智能化程度较高。
在一种可能的实现方式中，所述控制器被进一步配置成采用如下方式获取所述参考路径：
在所述预设圆周路径上找到与所述滑动路径的起点距离最近的点，作为所述参考路径的起点；
在所述预设圆周路径上找到与所述滑动路径的终点距离最近的点，作为所述参考路径的终点；
基于所述滑动路径的路径方向，从所述预设圆周路径中截取所述参考路径的起点到终点之间的路径作为所述参考路径。
该技术方案的有益效果在于：以预设圆周路径上与滑动路径的起点距离最近的点作为参考路径的起点，以预设圆周路径上与滑动路径的终点距离最近的点作为参考路径的终点，截取预设圆周路径中沿滑动路径的路径方向从参考路径的起点到终点之间的路径作为参考路径，由此得到的参考路径较为贴合滑动路径，根据该参考路径获取对应的配置参数值较为合理，能够真实反应用户在配置参数时 的意图。
在一种可能的实现方式中，所述控制器被进一步配置成采用如下方式获取所述相似度：
获取多个相似度训练数据，每个所述相似度训练数据包括用于训练的样本滑动路径、样本参考路径以及二者的标注相似度；
利用多个所述相似度训练数据训练预设的深度学习模型，得到相似度模型；
将所述滑动路径和所述参考路径输入所述相似度模型，得到所述相似度。
该技术方案的有益效果在于：可以根据相似度训练数据训练预设的深度学习模型，得到相似度模型，只需将滑动路径和参考路径输入相似度模型，即可实时地自动生成对应的相似度，智能化程度较高。通过设计，建立适量的神经元计算节点和多层运算层次结构，选择合适的输入层和输出层，就可以得到预设的深度学习模型，通过该预设的深度学习模型的学习和调优，建立起从输入到输出的函数关系，虽然不能100％找到输入与输出的函数关系，但是可以尽可能地逼近现实的关联关系，由此训练得到的相似度模型，可以实时输出对应的相似度，且输出结果可靠性高。
在一种可能的实现方式中，所述控制器被进一步配置成采用如下方式获取所述预设相似度阈值：
获取疾病类型和相似度阈值之间的第一对应关系；
基于所述患者的疾病类型和所述第一对应关系，获取所述患者的疾病类型对应的相似度阈值作为所述预设相似度阈值。
该技术方案的有益效果在于：疾病类型不同的患者的手部控制的能力可能不同，相比于手部控制力强的患者，手部控制力较差的帕金森患者在滑动时滑动路径与预设圆周路径的偏差可能较大，相似度可能较低，针对不同疾病类型的患者，采用不同的预设相似度阈值，使得程控设备可以支持手部控制力较差的患者进行滑动操作，大大降低了患者在使用程控设备时的操作难度。
在一种可能的实现方式中，所述控制器被进一步配置成采用如下方式获取所述目标参数的配置参数值：
获取所述预设圆周路径对应的所述目标参数的量程；
基于所述参考路径与所述预设圆周路径的长度之比和所述目标参数的量程， 确定所述目标参数的配置参数值。
该技术方案的有益效果在于：可以基于参考路径与预设圆周路径的长度之比和目标参数的量程，对目标参数的参数值进行无极调节，目标参数的配置参数值可以是目标参数的量程内的任意值，满足实际应用中的需求。
在一种可能的实现方式中，所述预设圆周路径设置有至少一个刻度，所述控制器被进一步配置成采用如下方式获取所述目标参数的配置参数值：
获取所述预设圆周路径对应的所述目标参数的量程以及所述预设圆周路径的每个刻度对应的所述目标参数的设定值；
基于所述参考路径的终点最接近的刻度对应的所述目标参数的设定值，确定所述目标参数的配置参数值。
该技术方案的有益效果在于：可以基于参考路径最接近的刻度对应的目标参数的设定值，对目标参数的参数值进行调节得到目标参数的配置参数值，目标参数的配置参数值可以是多个刻度对应的目标参数的设定值中的其中一个，满足实际应用中的需求。
在一种可能的实现方式中，所述控制器采用如下方式获取所述目标参数的量程：
获取关联参数的配置参数值和所述目标参数的量程的第二对应关系，所述关联参数为所述刺激器的参数中所述目标参数以外的一个或多个参数；
基于关联参数的配置参数值和所述第二对应关系，获取所述目标参数的量程。
该技术方案的有益效果在于：刺激器的每个参数的配置过程并非是孤立的，每个参数的配置参数值与其他参数的量程是相关联的，使得在设置参数时只能在相对合理的量程内完成，避免用户设置不合理的参数值，保障患者的生命安全。
在一种可能的实现方式中，所述预设圆周路径沿自身的顺时针方向依次设置有N个刻度，第k个刻度对应的所述目标参数的设定值和第k-1个刻度对应的所述目标参数的设定值之间的差值小于第k+1个刻度对应的所述目标参数的设定值和第k个刻度对应的所述目标参数的设定值之间的差值，N为大于2的整数，k为大于1小于N的整数。
该技术方案的有益效果在于：沿着预设圆周路径自身的顺时针方向，相邻两个刻度对应的所述目标参数的设定值的差值越来越大，使得用户在顺时针滑动的 过程中，轨迹点对应的设定值的幅度变化逐渐变快，进一步加快参数值设置的效率。
在一种可能的实现方式中，所述控制器还被配置成：
当检测到所述滑动路径的任意一个轨迹点的位置不处于所述预设滑动区域时，不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述预设滑动区域。
该技术方案的有益效果在于：当滑动路径的任意一个轨迹点的位置不处于预设滑动区域时，表明滑动操作可能为用户误操作所致，判断本次滑动操作无效，此时，可以不做任何操作，通过滑动操作后没有反应的方式进行间接提示用户滑动操作无效，或者提示用户重新操作，或者在触摸屏以闪烁的状态显示预设滑动区域，通过以上任意一种处理方式，均可以起到提示用户本次滑动操作无效的作用，智能化程度较高。
在一种可能的实现方式中，所述控制器还被配置成：
当所述相似度小于所述预设相似度阈值时，不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述预设圆周路径。
该技术方案的有益效果在于：当相似度小于预设相似度阈值时，表明滑动操作可能为用户误触所致，判断本次滑动操作无效，此时，可以不做任何操作，通过滑动操作后没有反应的方式进行间接提示用户滑动操作无效，或者提示用户重新操作，或者在触摸屏以闪烁的状态显示预设圆周路径，通过以上任意一种处理方式，均可以起到提示用户本次滑动操作无效的作用，智能化程度较高。
在一种可能的实现方式中，所述目标参数为电压的脉宽参数、幅值参数和频率参数中的任意一个。
该技术方案的有益效果在于：目标参数可以是电压的脉宽参数、幅值参数和频率参数中的任意一个，使得程控设备可以基于目标参数的配置参数值控制刺激器向患者施加相应的电刺激，满足实际应用的需求。
在一种可能的实现方式中，所述患者的疾病类型包括癫痫、震颤、帕金森病、抑郁症、强迫症、阿尔茨海默症和药物成瘾症中的一个或多个。
该技术方案的有益效果在于：利用程控设备可以对疾病类型不同的患者体内的刺激器进行控制，适用范围较广。
第二方面，本申请提供了一种植入式神经刺激系统，所述植入式神经刺激系统包括设置于患者体外的所述程控设备和植入于所述患者体内的刺激器；
所述刺激器被配置成生成电刺激并向所述患者的体内组织施加所述电刺激；
所述程控设备与所述刺激器可通信地连接，所述程控设备包括：
触摸屏，所述触摸屏被配置成接收用户的操作；
通信模块，所述通信模块被配置成实现所述程控设备与所述刺激器之间的数据交互；
控制器，所述控制器分别与所述触摸屏和所述通信模块电连接，所述控制器被配置成：
利用所述触摸屏接收滑动操作，响应于所述滑动操作，获取目标参数的配置参数值；
基于所述目标参数的配置参数值，生成控制指令并发送至所述刺激器，以使所述刺激器根据所述控制指令生成所述电刺激。
该技术方案的有益效果在于：本申请的植入式神经刺激系统可以支持用户的滑动操作，用户可以通过滑动的方式设置参数值，大大减少了用户的操作步骤，使得参数值设置更为快速便捷，提升用户的使用体验。
附图说明
下面结合附图和实施例对本申请进一步说明。
图1是本申请实施例提供的一种程控设备的控制方法的流程示意图；
图2是本申请实施例提供的一种获取目标参数的配置参数值的流程示意图；
图3是本申请实施例提供的一种触摸屏的显示界面的示意图；
图4是本申请实施例提供的另一种程控设备的控制方法的流程示意图；
图5是本申请实施例提供的一种获取参考路径的流程示意图；
图6是本申请实施例提供的一种获取相似度的流程示意图；
图7是本申请实施例提供的一种获取预设相似度阈值的流程示意图；
图8是本申请实施例提供的另一种获取目标参数的配置参数值的流程示意图；
图9是本申请实施例提供的又一种获取目标参数的配置参数值的流程示意图；
图10是本申请实施例提供的一种程控设备的控制方法的部分流程示意图；
图11是本申请实施例提供的另一种程控设备的控制方法的部分流程示意图；
图12是本申请实施例提供的一种程控设备的结构框图；
图13是本申请实施例提供的一种植入式神经刺激系统的结构框图。
具体实施方式
下面，结合附图以及具体实施方式，对本申请做进一步描述，需要说明的是，在不相冲突的前提下，以下描述的各实施例之间或各技术特征之间可以任意组合形成新的实施例。
在本申请中，“至少一个”是指一个或者多个，“多个”是指两个或两个以上。“和/或”，描述关联对象的关联关系，表示可以存在三种关系，例如，A和/或B，可以表示：单独存在A，同时存在A和B，单独存在B的情况，其中A，B可以是单数或者复数。字符“/”一般表示前后关联对象是一种“或”的关系。“以下至少一项(个)”或其类似表达，是指的这些项中的任意组合，包括单项(个)或复数项(个)的任意组合。例如，a，b或c中的至少一项(个)，可以表示：a，b，c，a和b，a和c，b和c或a和b和c，其中a、b和c可以是单个，也可以是多个。值得注意的是，“至少一项(个)”还可以解释成“一项(个)或多项(个)”。
本申请中，“示例性的”或者“例如”等词用于表示作例子、例证或说明。本申请中被描述为“示例性的”或者“例如”的任何实施例或设计方案不应被解释为比其他实施例或设计方案更优选或更具优势。确切而言，使用“示例性的”或者“例如”等词旨在以具体方式呈现相关概念。
下面，首先对本申请实施例的其中一个应用领域(即植入式神经刺激器)进行简单说明。
植入式神经刺激系统(一种植入式医疗系统)主要包括植入患者体内的刺激器(即植入式神经刺激器)以及设置于患者体外的程控设备。程控设备可以包括体外控制器，程控设备也可以就是体外控制器。现有的神经调控技术主要是通过立体定向手术在体内特定结构(即靶点)植入电极，并由植入患者体内的刺激器经电极向靶点发放电脉冲，调控相应神经结构和网络的电活动及其功能，从而改善症状、缓解病痛。其中，刺激器可以是植入式神经电刺激装置、植入式心脏电刺激系统(又称心脏起搏器)、植入式药物输注装置(Implantable Drug Delivery Sy stem，简称I DDS)和导线转接装置中的任意一种。植入式神经电刺激装置例如是脑深部电刺激系统(Deep Brain Stimulation，简称DBS)、植入式脑皮层刺激系统(Cortical Nerve Stimulation，简称CNS)、植入式脊髓电刺激系统(Spinal Cord Stimulation，简称SCS)、植入式骶神经电刺激系统(Sacral Nerve Stimulation，简称SNS)、植入式迷走神经电刺激系统(Vagus Nerve Stimulation，简称VNS)等。
刺激器可以包括IPG、延伸导线和电极导线，IPG(implantable pulse generator，植入式脉冲发生器)设置于患者体内，接收程控设备发送的程控指令，依靠密封电池和电路向体内组织提供可控制的电刺激能量，通过植入的延伸导线和电极导线，为体内组织的特定区域递送一路或两路可控制的特定电刺激。延伸导线配合IPG使用，作为电刺激信号的传递媒体，将IPG产生的电刺激信号，传递给电极导线。电极导线通过多个电极触点，向体内组织的特定区域递送电刺激。刺激器设置有单侧或双侧的一路或多路电极导线，电极导线上设置有多个电极触点，电极触点可以均匀排列或者非均匀排列在电极导线的周向上。作为一个示例，电极触点可以以4行3列的阵列(共计12个电极触点)排列在电极导线的周向上。电极触点可以包括刺激电极触点和/或采集电极触点。电极触点例如可以采用片状、环状、点状等形状。
在一些可能的实施方式中，受刺激的体内组织可以是患者的脑组织，受刺激的部位可以是脑组织的特定部位。当患者的疾病类型不同时，受刺激的部位一般来说是不同的，所使用的刺激触点(单源或多源)的数量、一路或多路(单通道或多通道)特定电刺激信号的运用以及刺激参数数据也是不同的。本申请实施例对适用的疾病类型不做限定，其可以是脑深部刺激(DBS)、脊髓刺激(SCS)、骨盆刺激、胃刺激、外周神经刺激、功能性电刺激所适用的疾病类型。其中，DBS可以用于治疗或管理的疾病类型包括但不限于：痉挛疾病(例如，癫痫)、疼痛、偏头痛、精神疾病(例如，重度抑郁症(MDD))、躁郁症、焦虑症、创伤后压力心理障碍症、轻郁症、强迫症(OCD)、行为障碍、情绪障碍、记忆障碍、心理状态障碍、移动障碍(例如，特发性震颤或帕金森氏病)、亨廷顿病、阿尔茨海默症、药物成瘾症、孤独症或其他神经学或精神科疾病和损害。
本申请实施例中，程控设备和刺激器建立程控连接时，可以利用程控设备调 整刺激器的刺激参数(不同的刺激参数所对应的电刺激信号不同)，也可以通过刺激器感测患者脑深部的生物电活动以采集得到电生理信号，并可以通过所采集到的电生理信号来继续调节刺激器的电刺激信号的刺激参数。
刺激参数可以包括：频率(例如是单位时间1s内的电刺激脉冲信号个数，单位为Hz)、脉宽(每个脉冲的持续时间，单位为μs)、幅值(一般用电压表述，即每个脉冲的强度，单位为V)、时序(例如可以是连续或者触发)、刺激模式(包括电流模式、电压模式、定时刺激模式和循环刺激模式中的一种或多种)、医生控制上限及下限(医生可调节的范围)和患者控制上限及下限(患者可自主调节的范围)中的一种或多种。
在一个具体应用场景中，可以在电流模式或者电压模式下对刺激器的各刺激参数进行调节。
程控设备可以是医生程控设备(即医生使用的程控设备)或者患者程控设备(即患者使用的程控设备)。医生程控设备例如可以是搭载有程控软件的平板电脑、笔记本电脑、台式计算机、手机等智能终端设备。患者程控设备例如可以是搭载有程控软件的平板电脑、笔记本电脑、台式计算机、手机等智能终端设备，患者程控设备还可以是其他具有程控功能的电子设备(例如是具有程控功能的充电器、数据采集设备)。
本申请实施例对医生程控设备和刺激器的数据交互不进行限制，当医生远程程控时，医生程控设备可以通过服务器、患者程控设备与刺激器进行数据交互。当医生线下和患者面对面进行程控时，医生程控设备可以通过患者程控设备与刺激器进行数据交互，医生程控设备还可以直接与刺激器进行数据交互。
在一些可选的实施方式中，患者程控设备可以包括(与服务器通信的)主机和(与刺激器通信的)子机，主机和子机可通信的连接。其中，医生程控设备可以通过3G/4G/5G网络与服务器进行数据交互，服务器可以通过3G/4G/5G网络与主机进行数据交互，主机可以通过蓝牙协议/WIFI协议/USB协议与子机进行数据交互，子机可以通过401MHz-406MHz工作频段/2.4GHz-2.48GHz工作频段与刺激器进行数据交互，医生程控设备可以通过401MHz-406MHz工作频段/2.4GHz-2.48GHz工作频段与刺激器直接进行数据交互。
参见图1，本申请实施例提供了一种程控设备的控制方法，应用于植入式神 经刺激系统，所述植入式神经刺激系统包括设置于患者体外的所述程控设备和植入于所述患者体内的刺激器；
所述程控设备与所述刺激器可通信地连接，所述程控设备包括：
触摸屏，所述触摸屏被配置成接收用户的操作；
通信模块，所述通信模块被配置成实现所述程控设备与所述刺激器之间的数据交互；
所述方法包括步骤S101～步骤S102。
步骤S101：利用所述触摸屏接收滑动操作，响应于所述滑动操作，获取目标参数的配置参数值；
步骤S102：基于所述目标参数的配置参数值，生成控制指令并发送至所述刺激器，以使所述刺激器根据所述控制指令生成电刺激并向所述患者的体内组织施加所述电刺激。
一般而言，现有的程控设备在设置参数值时需要输入具体数值或者通过多次按键操作逐步调节，参数值设置效率低下，本申请的程控设备可以支持用户的滑动操作，用户可以通过滑动的方式设置参数值，大大减少了用户的操作步骤，使得参数值设置更为快速便捷，提升用户的使用体验。
刺激器可以是植入式神经电刺激装置、植入式心脏电刺激系统(又称心脏起搏器)、植入式药物输注装置(Implantable Drug Delivery System，简称I DDS)和导线转接装置中的任意一种。植入式神经电刺激装置例如是脑深部电刺激系统(Deep Brain Stimulation，简称DBS)，植入式脑皮层刺激系统(Cortical Nerve Stimulation，简称CNS)，植入式脊髓电刺激系统(Spinal Cord Stimulation，简称SCS)，植入式骶神经电刺激系统(Sacral Nerve Stimulation，简称SNS)，植入式迷走神经电刺激系统(Vagus Nerve Stimulation，简称VNS)等。刺激器设置于患者体内，用于提供电刺激。
程控设备可以包括但不限于：智能手机(如Android手机、iOS手机等)、平板电脑、便携式个人计算机、移动互联网设备(Mobile Internet Devices，MID)等设备，本申请实施例不做限定。
在一些实施方式中，程控设备可以包括医生程控设备和/或患者程控设备。
患者程控设备是为患者配备的，患者可以利用患者程控设备自行调节对应的 刺激器的参数。具体地，可以基于患者的疾病信息设置对应的预设调节范围，患者只能在对应的预设调节范围内调节对应的刺激器的参数。
医生程控设备是为医生配备的，一个医生程控设备可以利用通信模块分别与多个患者的刺激器进行数据交互。
在一些实施方式中，通信模块可以包括有线通信模块和/或无线通信模块。
有线通信模块可以包括光纤通信单元、同轴电缆通信单元、明线通信单元、波导通信单元和光电通信单元中的一个或多个；无线通信模块可以包括4G通信单元、5G通信单元、WIFI通信单元、近场通信单元、WiGig通信单元、蓝牙通信单元、ZigBee通信单元、微波通信单元、卫星通信单元和大气激光通信单元中的一个或多个。
有线通信模块较为稳定，且可靠性高、传输速率高；无线通信模块的通信距离更长，且不受线的限制，具有一定的移动性，可以在移动状态下通过无线连接进行通信，成本较低。
在一些实施方式中，触摸屏可以包括电阻式触摸屏、电容式触摸屏和表面声波屏中的任意一个。
在一种可能的实现方式中，所述目标参数可以为电压的脉宽参数、幅值参数和频率参数中的任意一个。
在一种可能的实现方式中，所述目标参数可以为电流的脉宽参数、幅值参数和频率参数中的任意一个。
由此，目标参数可以是脉宽参数、幅值参数和频率参数中的任意一个，使得程控设备可以基于目标参数的配置参数值控制刺激器向患者施加相应的电刺激，满足实际应用的需求。
参见图2，在一种可能的实现方式中，所述步骤S101可以包括步骤S201～步骤S204。
步骤S201：响应于所述滑动操作，获取所述目标参数对应的滑动路径；
步骤S202：当检测到所述滑动路径的各轨迹点的位置均处于预设滑动区域时，基于所述滑动路径的起点、终点和路径方向，获取所述滑动路径对应的参考路径，所述参考路径是预设圆周路径的一部分且所述参考路径的路径方向由所述滑动路径的路径方向确定，所述预设圆周路径处于所述预设滑动区域；
步骤S203：获取所述滑动路径和所述参考路径的相似度；
步骤S204：当所述相似度不小于预设相似度阈值时，基于所述参考路径，获取所述目标参数的配置参数值。
由此，使用两个阶段的检测过程来判断是否为误操作，只有判断滑动操作不是误操作时才获取配置参数值，当第一阶段检测到滑动路径的各轨迹点的位置均处于预设滑动区域时，并非直接进行配置参数值的计算，而是进入第二阶段的检测，当检测到相似度不小于预设相似度阈值时，才确定滑动操作不是误操作，进而获取配置参数值，两个阶段的检测过程可以起到双重保险的作用，避免用户因为误操作而设置不合理的参数值，保障患者的生命安全。
具体而言，在第一阶段，检测所述滑动路径的各轨迹点的位置是否均处于预设滑动区域，当检测到所述滑动路径的各轨迹点的位置均处于预设滑动区域时，表明用户可能有配置参数的意图，这时进入第二阶段；在第二阶段，基于滑动路径的起点、终点和路径方向，获取滑动路径对应的参考路径，获取滑动路径和参考路径的相似度，检测相似度是否不小于预设相似度阈值，当相似度不小于预设相似度阈值时，可以确定滑动操作并非误操作。
参见图3，在一些实施方式中，预设滑动区域的形状可以是与预设圆周路径同心的圆环。
本申请对滑动路径的长度不做限定，用户可以沿触摸屏的预设滑动区域滑动不足一圈，也可以，也可以沿触摸屏的预设滑动区域滑动多圈(总圈数可以不是整数)。
参考路径可以是不足一个预设圆周路径，也可以是一个预设圆周路径，也可以是非整数个预设圆周路径(例如1.5个、3.5个等)。当用户滑动0.3圈时，参考路径例如是0.3圈预设圆周路径；当用户滑动1圈时，参考路径例如是1圈预设圆周路径；当用户滑动4.5圈时，参考路径例如是4.5圈预设圆周路径。
参见图3和图4，在一种可能的实现方式中，所述方法还可以包括步骤S205～步骤S207。
步骤S205：在步骤S202之前，检测所述滑动路径的起点是否处于有效起点范围，所述有效起点范围包括所述目标参数的当前参数值对应的所述触摸屏上的位置点；
步骤S206：如果所述滑动路径的起点处于所述有效起点范围，则检测所述滑动路径的各轨迹点的位置是否均处于所述预设滑动区域；
步骤S207：如果所述滑动路径的起点不处于所述有效起点范围，则不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述有效起点范围对应的区域。
由此，检测滑动路径的起点是否处于有效起点范围，若滑动路径的起点不处于有效起点范围，表明滑动操作可能为用户误操作，此时，可以不做任何操作，通过滑动操作后没有反应的方式进行间接提示用户滑动操作无效，或者，直接提示用户重新操作，或者，在触摸屏以闪烁的状态显示有效起点范围对应的区域，以上任意一种处理方式均可以起到提示用户本次滑动操作无效的作用，智能化程度较高。
有效起点范围例如是以目标参数的当前参数值对应的触摸屏上的位置点为圆心，以预设尺寸为半径的圆形；或者，有效起点范围例如是以目标参数的当前参数值对应的触摸屏上的位置点为中心，以预设尺寸为边长的正方形。预设尺寸例如是8mm、10mm或者20mm。
参见图5，在一种可能的实现方式中，所述步骤S202可以包括步骤S301～步骤S303。
步骤S301：在所述预设圆周路径上找到与所述滑动路径的起点距离最近的点，作为所述参考路径的起点；
步骤S302：在所述预设圆周路径上找到与所述滑动路径的终点距离最近的点，作为所述参考路径的终点；
步骤S303：基于所述滑动路径的路径方向，从所述预设圆周路径中截取所述参考路径的起点到终点之间的路径作为所述参考路径。
由此，以预设圆周路径上与滑动路径的起点距离最近的点作为参考路径的起点，以预设圆周路径上与滑动路径的终点距离最近的点作为参考路径的终点，截取预设圆周路径中沿滑动路径的路径方向从参考路径的起点到终点之间的路径作为参考路径，由此得到的参考路径较为贴合滑动路径，根据该参考路径获取对应的配置参数值较为合理，能够真实反应用户在配置参数时的意图。
参见图6，在一种可能的实现方式中，所述步骤S203可以包括步骤S401～ 步骤S403。
步骤S401：获取多个相似度训练数据，每个所述相似度训练数据包括用于训练的样本滑动路径、样本参考路径以及二者的标注相似度；
步骤S402：利用多个所述相似度训练数据训练预设的深度学习模型，得到相似度模型；
步骤S403：将所述滑动路径和所述参考路径输入所述相似度模型，得到所述相似度。
由此，可以根据相似度训练数据训练预设的深度学习模型，得到相似度模型，只需将滑动路径和参考路径输入相似度模型，即可实时地自动生成对应的相似度，智能化程度较高。通过设计，建立适量的神经元计算节点和多层运算层次结构，选择合适的输入层和输出层，就可以得到预设的深度学习模型，通过该预设的深度学习模型的学习和调优，建立起从输入到输出的函数关系，虽然不能100％找到输入与输出的函数关系，但是可以尽可能地逼近现实的关联关系，由此训练得到的相似度模型，可以实时输出对应的相似度，且输出结果可靠性高。
参见图7，在一种可能的实现方式中，所述预设相似度阈值可以采用步骤S501～步骤S502获取。
步骤S501：获取疾病类型和相似度阈值之间的第一对应关系；
步骤S502：基于所述患者的疾病类型和所述第一对应关系，获取所述患者的疾病类型对应的相似度阈值作为所述预设相似度阈值。
由此，疾病类型不同的患者的手部控制的能力可能不同，相比于手部控制力强的患者，手部控制力较差的帕金森患者在滑动时滑动路径与预设圆周路径的偏差可能较大，相似度可能较低，针对不同疾病类型的患者，采用不同的预设相似度阈值，使得程控设备可以支持手部控制力较差的患者进行滑动操作，大大降低了患者在使用程控设备时的操作难度。
在一具体应用中，帕金森病对应的相似度阈值为60％，抑郁症对应的相似度阈值为80％，药物成瘾症对应的相似度阈值为85％。
例如患者张三为帕金森患者，则张三的预设相似度阈值为60％。当患者的疾病类型大于一种时，可以以该患者所有疾病类型对应的相似度阈值中最低的一个作为该患者的预设相似度阈值。
本申请的程控设备对适用的疾病类型不做限定，疾病类型包括但不限于：痉挛疾病(例如，癫痫)、疼痛、偏头痛、精神疾病(例如，重度抑郁症(MDD))、躁郁症、焦虑症、创伤后压力心理障碍症、轻郁症、强迫症(OCD)、行为障碍、情绪障碍、记忆障碍、心理状态障碍、移动障碍(例如，震颤或帕金森病)、亨廷顿病、阿尔茨海默症、药物成瘾症或其他神经学或精神科疾病和损害。当程控设备用于治疗药物成瘾症患者时，可以帮助吸毒人员戒毒，提升他们的幸福感和生命质量。
在一种可能的实现方式中，所述患者的疾病类型包括癫痫、震颤、帕金森病、抑郁症、强迫症、阿尔茨海默症和药物成瘾症中的一个或多个。
由此，利用程控设备可以对疾病类型不同的患者体内的刺激器进行控制，适用范围较广。
参见图8，在一种可能的实现方式中，所述步骤S204可以包括步骤S601～步骤S602。
步骤S601：获取所述预设圆周路径对应的所述目标参数的量程；
步骤S602：基于所述参考路径与所述预设圆周路径的长度之比和所述目标参数的量程，确定所述目标参数的配置参数值。
其中，所述目标参数的量程用于指示所述目标参数的第一设定值和第二设定值。
量程是指度量工具的测量范围，量程由度量工具的分度值、最大测量值决定。仪表的量程为仪表标称范围的上下两极限之差的值。如果仪表的测量下限为零，则所能测量的物理量的最大值等于其量程。
由此，可以基于参考路径与预设圆周路径的长度之比和目标参数的量程，对目标参数的参数值进行无极调节，目标参数的配置参数值可以是目标参数的量程内的任意值，满足实际应用中的需求。
在一些实施方式中，所述步骤S602可以包括：
基于所述参考路径与所述预设圆周路径的长度之比、所述参考路径的路径方向、所述目标参数的当前参数值和所述目标参数的量程，确定所述目标参数的配置参数值。
当参考路径不足一个预设圆周路径时，目标参数的第一设定值可以是目标参 数的最小设定值，目标参数的第二设定值可以是目标参数的最大设定值。一般而言，配置参数值处于最小设定值和最大设定值之间的范围。
在一具体应用中，目标参数为刺激器的电压脉宽参数，电压脉宽参数的量程为0～960μs，电压脉宽参数的第一设定值为0μs，第二设定值为960μs。
参考路径与预设圆周路径的长度之比为0.5，参考路径的路径方向为顺时针，电压脉宽参数的当前参数值为20μs，则电压脉宽参数的配置参数值为20μs+0.5×(960-0)μs＝500μs。
当参考路径为一个以上(非整数倍)预设圆周路径(例如1.5个、3.5个等)时，目标参数的第一设定值和第二设定值可以均处于目标参数的最小设定值和最大设定值之间的范围。
上述方式可以支持用户沿触摸屏的预设滑动区域滑动多圈，当目标参数的参数值的调节范围较大时，若只允许用户滑动一圈，用户不便在一圈的范围内进行精细把控，极容易造成参数值设置得偏高或偏低，而本申请的程控设备可以支持用户沿触摸屏的预设滑动区域滑动多圈，便于用户进行精细调节。
在一具体应用中，目标参数为刺激器的电压幅值参数，电压幅值参数的第一设定值为0V，第二设定值为0.6V。
参考路径为3.5个预设圆周路径，参考路径与预设圆周路径的长度之比为3.5，参考路径的路径方向为逆时针，电压幅值参数的当前参数值为2.35V，则电压幅值参数的配置参数值为2.35V-3.5×(0.6-0)V＝0.25V。
参见图9，在一种可能的实现方式中，所述预设圆周路径设置有至少一个刻度，所述步骤S204可以包括步骤S701～步骤S702。
步骤S701：获取所述预设圆周路径对应的所述目标参数的量程以及所述预设圆周路径的每个刻度对应的所述目标参数的设定值；
步骤S702：基于所述参考路径最接近的刻度对应的所述目标参数的设定值，确定所述目标参数的配置参数值。
由此，可以基于参考路径最接近的刻度对应的目标参数的设定值，对目标参数的参数值进行调节得到目标参数的配置参数值，目标参数的配置参数值可以是多个刻度对应的目标参数的设定值中的其中一个，满足实际应用中的需求。
在一具体应用中，目标参数为电压脉宽参数，预设圆周路径设置有20个刻 度，这20个刻度对应的电压脉宽参数的设定值依次为20μs、40μs、60μs、80μs、100μs、120μs……960μs，参考路径的终点最接近的刻度为第4个刻度，则电压脉宽参数的配置参数值为80μs。
在一种可能的实现方式中，所述步骤S601或者所述步骤S701采用如下方式获取所述目标参数的量程：
获取关联参数的配置参数值和所述目标参数的量程的第二对应关系，所述关联参数为所述刺激器的参数中所述目标参数以外的一个或多个参数；(所述目标参数是所述刺激器的参数的其中一个，所述刺激器的参数包括恒定电流的幅值参数、恒定电流的频率参数、恒定电压的幅值参数、恒定电压的脉宽参数、恒定电压的频率中参数的多个。)
基于关联参数的配置参数值和所述第二对应关系，获取所述目标参数的量程。
由此，刺激器的每个参数的配置过程并非是孤立的，每个参数的配置参数值与其他参数的量程是相关联的，使得在设置参数时只能在相对合理的量程内完成，避免用户设置不合理的参数值，保障患者的生命安全。
在一种可能的实现方式中，所述预设圆周路径设置有多个刻度，滑动路径对应的参考路径不大于1个预设圆周路径，目标参数的量程用于指示所述目标参数的最小设定值和最大设定值。
在一种可能的实现方式中，所述目标参数的量程包括可操作部分和不可操作部分，所述方法还包括：在所述触摸屏以第一状态显示所述目标参数的量程的可操作部分对应的刻度，以及，在所述触摸屏以第二状态显示所述目标参数的量程的不可操作部分对应的刻度以外的刻度；
当检测到所述参考路径的终点最接近的刻度处于所述目标参数的量程的不可操作部分对应的刻度范围时，不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述目标参数的量程的可操作部分对应的刻度。
在一具体应用中，对应的目标参数为电压频率参数，电压频率参数对应的关联参数为电压幅值参数，电压幅值参数的配置参数值为0.2V，则电压频率参数的量程为40Hz～120Hz；而当电压幅值参数的配置参数值为0.3V时，电压频率参数的量程可以为60Hz～160Hz。
预设圆周路径设置有8个刻度，在设置电压频率参数时，这8个刻度对应的 设定值依次为20Hz、40Hz、60Hz、80Hz、100Hz、120Hz、140Hz和160Hz。电压频率参数的量程的可操作部分对应的刻度包括第2个刻度至第6个刻度。
在触摸屏上以绿色的状态显示第2个刻度至第6个刻度，以红色或者灰色的状态显示第1个刻度、第7个刻度和第8个刻度。其中，绿色状态对应的刻度范围可操作，红色或者灰色的状态对应的刻度范围不可操作。
在一种可能的实现方式中，所述预设圆周路径沿自身的顺时针方向依次设置有N个刻度，第k个刻度对应的所述目标参数的设定值和第k-1个刻度对应的所述目标参数的设定值之间的差值与第k+1个刻度对应的所述目标参数的设定值和第k个刻度对应的所述目标参数的设定值之间的差值相同，N为大于2的整数，k为大于1小于N的整数。在一些具体应用中，(程控设备的控制器)可以利用触摸屏显示所述N个刻度的参数值。
在一具体应用中，目标参数为电压幅值参数，预设圆周路径沿滑动路径的路径方向依次设置有255个刻度，相邻两个刻度对应的电压幅值参数的设定值之间的差值为定值0.05V，这255个刻度对应的电压幅值参数的设定值依次为0.05V、0.1V、0.15V、0.2V、0.25V、0.3V……12.75V。
由此，N个刻度对应标参数的设定值组成等差数列，符合用户的操作习惯。
在一种可能的实现方式中，所述预设圆周路径沿自身的顺时针方向依次设置有N个刻度，第k个刻度对应的目标参数的设定值和第k-1个刻度对应的目标参数的设定值之间的差值与第k+1个刻度对应的目标参数的设定值和第k个刻度对应的目标参数的设定值之间的差值不同。
在一具体应用中，目标参数为电压频率参数，预设圆周路径沿滑动路径的路径方向依次设置有8个刻度，相邻两个刻度对应的电压频率参数的设定值之间的差值不为定值，这8个刻度对应的电压频率参数的设定值依次为20Hz、60Hz、100Hz、200Hz、210Hz、230Hz、240Hz和245Hz。
由此，可以根据实际应用的需要对任意一个刻度对应的目标参数的设定值进行灵活设置，适用范围较广。
在一种可能的实现方式中，所述预设圆周路径沿自身的顺时针方向依次设置有N个刻度，第k个刻度对应的目标参数的设定值和第k-1个刻度对应的目标参数的设定值之间的差值小于第k+1个刻度对应的目标参数的设定值和第k个刻度 对应的目标参数的设定值之间的差值。
由此，沿着预设圆周路径自身的顺时针方向，相邻两个刻度对应的所述目标参数的设定值的差值越来越大，使得用户在顺时针滑动的过程中，轨迹点对应的(刻度所对应的)设定值的幅度变化逐渐变快，进一步加快参数值设置的效率。
参见图10，在一种可能的实现方式中，所述方法还可以包括步骤S208。
步骤S208：当检测到所述滑动路径的任意一个轨迹点的位置不处于所述预设滑动区域时，不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述预设滑动区域。
由此，当滑动路径的任意一个轨迹点的位置不处于预设滑动区域时，表明滑动操作可能为用户误触所致，判断本次滑动操作无效，此时，可以不做任何操作，通过滑动操作后没有反应的方式进行间接提示用户滑动操作无效，或者提示用户重新操作，或者在触摸屏以闪烁的状态显示预设滑动区域，通过以上任意一种处理方式，均可以起到提示用户本次滑动操作无效的作用，智能化程度较高。
参见图11，在一种可能的实现方式中，所述方法还可以包括步骤S209。
步骤S209：当所述相似度小于所述预设相似度阈值时，不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述预设圆周路径。
由此，当相似度小于预设相似度阈值时，表明滑动操作可能为用户误触所致，判断本次滑动操作无效，此时，可以不做任何操作，通过滑动操作后没有反应的方式进行间接提示用户滑动操作无效，或者提示用户重新操作，或者在触摸屏以闪烁的状态显示预设圆周路径，通过以上任意一种处理方式，均可以起到提示用户本次滑动操作无效的作用，智能化程度较高。
参见图12，本申请还提供了一种程控设备100，其具体实现方式与上述控制方法的实施例中记载的实施方式、所达到的技术效果一致，部分内容不再赘述。
所述程控设备100应用于植入式神经刺激系统，所述植入式神经刺激系统包括设置于患者体外的所述程控设备100和植入于所述患者体内的刺激器；
所述程控设备100与所述刺激器可通信地连接，所述程控设备100包括：
触摸屏101，所述触摸屏101被配置成接收用户的操作；
通信模块102，所述通信模块102被配置成实现所述程控设备100与所述刺激器之间的数据交互；
控制器103，所述控制器103分别与所述触摸屏101和所述通信模块102电连接，所述控制器103被配置成：
利用所述触摸屏101接收滑动操作，响应于所述滑动操作，获取目标参数的配置参数值；
基于所述目标参数的配置参数值，生成控制指令并发送至所述刺激器，以使所述刺激器根据所述控制指令生成电刺激并向所述患者的体内组织施加所述电刺激。
在一些实施方式中，控制器103可以包括至少一个存储器、至少一个处理器以及连接不同平台系统的总线。其中，存储器可以包括随机存取存储器(RAM)、只读存储器(ROM)和高速缓存存储器中的一个或多个。存储器存储有计算机程序，该计算机程序可以被处理器执行。总线可以为表示几类总线结构中的一种或多种，包括存储器总线、外围总线、图形加速端口或者使用多种总线结构中的任意总线结构的局域总线。
在一种可能的实现方式中，所述控制器103被进一步配置成采用如下方式获取所述目标参数的配置参数值：
响应于所述滑动操作，获取所述目标参数对应的滑动路径；
当检测到所述滑动路径的各轨迹点的位置均处于预设滑动区域时，基于所述滑动路径的起点、终点和路径方向，获取所述滑动路径对应的参考路径，所述参考路径是预设圆周路径的一部分且所述参考路径的路径方向由所述滑动路径的路径方向确定，所述预设圆周路径处于所述预设滑动区域；
获取所述滑动路径和所述参考路径的相似度；
当所述相似度不小于预设相似度阈值时，基于所述参考路径，获取所述目标参数的配置参数值。
在一种可能的实现方式中，所述控制器103还被配置成：
在检测所述滑动路径的各轨迹点的位置是否均处于所述预设滑动区域之前，检测所述滑动路径的起点是否处于有效起点范围，所述有效起点范围包括所述目标参数的当前参数值对应的所述触摸屏101上的位置点；
如果所述滑动路径的起点处于所述有效起点范围，则检测所述滑动路径的各轨迹点的位置是否均处于所述预设滑动区域；
如果所述滑动路径的起点不处于所述有效起点范围，则不做任何操作，或者提示用户重新操作，或者在所述触摸屏101以闪烁的状态显示所述有效起点范围对应的区域。
在一种可能的实现方式中，所述控制器103被进一步配置成采用如下方式获取所述参考路径：
在所述预设圆周路径上找到与所述滑动路径的起点距离最近的点，作为所述参考路径的起点；
在所述预设圆周路径上找到与所述滑动路径的终点距离最近的点，作为所述参考路径的终点；
基于所述滑动路径的路径方向，从所述预设圆周路径中截取所述参考路径的起点到终点之间的路径作为所述参考路径。
在一种可能的实现方式中，所述控制器103被进一步配置成采用如下方式获取所述相似度：
获取多个相似度训练数据，每个所述相似度训练数据包括用于训练的样本滑动路径、样本参考路径以及二者的标注相似度；
利用多个所述相似度训练数据训练预设的深度学习模型，得到相似度模型；
将所述滑动路径和所述参考路径输入所述相似度模型，得到所述相似度。
在一种可能的实现方式中，所述控制器103被进一步配置成采用如下方式获取所述预设相似度阈值：
获取疾病类型和相似度阈值之间的第一对应关系；
基于所述患者的疾病类型和所述第一对应关系，获取所述患者的疾病类型对应的相似度阈值作为所述预设相似度阈值。
在一种可能的实现方式中，所述控制器103被进一步配置成采用如下方式获取所述目标参数的配置参数值：
获取所述预设圆周路径对应的所述目标参数的量程；
基于所述参考路径与所述预设圆周路径的长度之比和所述目标参数的量程，确定所述目标参数的配置参数值。
在一种可能的实现方式中，所述预设圆周路径设置有至少一个刻度，所述控制器103被进一步配置成采用如下方式获取所述目标参数的配置参数值：
获取所述预设圆周路径对应的所述目标参数的量程以及所述预设圆周路径的每个刻度对应的所述目标参数的设定值；
基于所述参考路径的终点最接近的刻度对应的所述目标参数的设定值，确定所述目标参数的配置参数值。
在一种可能的实现方式中，所述控制器103采用如下方式获取所述预设圆周路径对应的所述目标参数的量程：
获取关联参数的配置参数值和所述预设圆周路径对应的所述目标参数的量程的第二对应关系，所述关联参数为所述刺激器的参数中所述目标参数以外的一个或多个参数；
基于关联参数的配置参数值和所述第二对应关系，获取所述目标参数的量程。
在一种可能的实现方式中，所述预设圆周路径沿自身的顺时针方向依次设置有N个刻度，第k个刻度对应的所述目标参数的设定值和第k-1个刻度对应的所述目标参数的设定值之间的差值小于第k+1个刻度对应的所述目标参数的设定值和第k个刻度对应的所述目标参数的设定值之间的差值，N为大于2的整数，k为大于1小于N的整数。
在一种可能的实现方式中，所述控制器103还被配置成：
当检测到所述滑动路径的任意一个轨迹点的位置不处于所述预设滑动区域时，不做任何操作，或者提示用户重新操作，或者在所述触摸屏101以闪烁的状态显示所述预设滑动区域。
在一种可能的实现方式中，所述控制器103还被配置成：
当所述相似度小于所述预设相似度阈值时，不做任何操作，或者提示用户重新操作，或者在所述触摸屏101以闪烁的状态显示所述预设圆周路径。
在一种可能的实现方式中，所述目标参数为电压的脉宽参数、幅值参数和频率参数中的任意一个。
在一种可能的实现方式中，所述患者的疾病类型包括癫痫、震颤、帕金森病、抑郁症、强迫症、阿尔茨海默症和药物成瘾症中的一个或多个。
参见图13，本申请还提供了一种植入式神经刺激系统300，其具体实现方式与上述控制方法的实施例中记载的实施方式、所达到的技术效果一致，部分内容不再赘述。
所述植入式神经刺激系统300包括设置于患者体外的所述程控设备100和植入于所述患者体内的刺激器；
所述刺激器被配置成生成电刺激并向所述患者的体内组织施加所述电刺激；
所述程控设备100与所述刺激器可通信地连接，所述程控设备100包括：
触摸屏101，所述触摸屏101被配置成接收用户的操作；
通信模块102，所述通信模块102被配置成实现所述程控设备100与所述刺激器之间的数据交互；
控制器103，所述控制器103分别与所述触摸屏101和所述通信模块102电连接，所述控制器103被配置成：
利用所述触摸屏101接收滑动操作，响应于所述滑动操作，获取目标参数的配置参数值；
基于所述目标参数的配置参数值，生成控制指令并发送至所述刺激器，以使所述刺激器根据所述控制指令生成所述电刺激。
由此，本申请的植入式神经刺激系统300可以支持用户的滑动操作，用户可以通过滑动的方式设置参数值，大大减少了用户的操作步骤，使得参数值设置更为快速便捷，提升用户的使用体验。
需要说明的是，本申请的说明书和权利要求书及上述附图中的术语“第一”、“第二”等是用于区别类似的对象，而不必用于描述特定的顺序或先后次序。应该理解这样使用的数据在适当情况下可以互换，以便这里描述的本申请的实施例能够以除了在这里图示或描述的那些以外的顺序实施。此外，术语“包括”和“具有”以及他们的任何变形，意图在于覆盖不排他的包含，例如，包含了一系列步骤或单元的过程、方法、系统、产品或设备不必限于清楚地列出的那些步骤或单元，而是可包括没有清楚地列出的或对于这些过程、方法、产品或设备固有的其它步骤或单元。
当一个部件被称作“在”另一部件“上”或“之上”、“连接到”或“结合到”另一部件时，该部件可以直接在所述另一部件上、直接连接到或直接结合到所述另一部件，或者可以存在中间部件。然而，当部件被称作“直接在”另一部件“上”、“直接连接到”或“直接结合到”另一部件时，不存在中间部件。为此，术语“连接”可以指物理连接、电气连接等，并且具有或不具有中间部件。
本申请从使用目的上，效能上，进步及新颖性等观点进行阐述，本申请以上的说明书及说明书附图，仅为本申请的较佳实施例而已，并非以此局限本申请，因此，凡一切与本申请构造，装置，特征等近似、雷同的，即凡依本申请专利申请范围所作的等同替换或修饰等，皆应属本申请的专利申请保护的范围之内。

Claims (15)

  1. 一种程控设备，应用于植入式神经刺激系统，所述植入式神经刺激系统包括设置于患者体外的所述程控设备和植入于所述患者体内的刺激器；
    所述程控设备与所述刺激器可通信地连接，所述程控设备包括：
    触摸屏，所述触摸屏被配置成接收用户的操作；
    通信模块，所述通信模块被配置成实现所述程控设备与所述刺激器之间的数据交互；
    控制器，所述控制器分别与所述触摸屏和所述通信模块电连接，所述控制器被配置成：
    利用所述触摸屏接收滑动操作，响应于所述滑动操作，获取目标参数的配置参数值；
    基于所述目标参数的配置参数值，生成控制指令并发送至所述刺激器，以使所述刺激器根据所述控制指令生成电刺激并向所述患者的体内组织施加所述电刺激。
  2. 根据权利要求1所述的程控设备，其中，所述控制器被进一步配置成采用如下方式获取所述目标参数的配置参数值：
    响应于所述滑动操作，获取所述目标参数对应的滑动路径；
    当检测到所述滑动路径的各轨迹点的位置均处于预设滑动区域时，基于所述滑动路径的起点、终点和路径方向，获取所述滑动路径对应的参考路径，所述参考路径是预设圆周路径的一部分且所述参考路径的路径方向由所述滑动路径的路径方向确定，所述预设圆周路径处于所述预设滑动区域；
    获取所述滑动路径和所述参考路径的相似度；
    当所述相似度不小于预设相似度阈值时，基于所述参考路径，获取所述目标参数的配置参数值。
  3. 根据权利要求2所述的程控设备，其中，所述控制器还被配置成：
    在检测所述滑动路径的各轨迹点的位置是否均处于所述预设滑动区域之前，检测所述滑动路径的起点是否处于有效起点范围，所述有效起点范围包括所述目 标参数的当前参数值对应的所述触摸屏上的位置点；
    如果所述滑动路径的起点处于所述有效起点范围，则检测所述滑动路径的各轨迹点的位置是否均处于所述预设滑动区域；
    如果所述滑动路径的起点不处于所述有效起点范围，则不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述有效起点范围对应的区域。
  4. 根据权利要求2所述的程控设备，其中，所述控制器被进一步配置成采用如下方式获取所述参考路径：
    在所述预设圆周路径上找到与所述滑动路径的起点距离最近的点，作为所述参考路径的起点；
    在所述预设圆周路径上找到与所述滑动路径的终点距离最近的点，作为所述参考路径的终点；
    基于所述滑动路径的路径方向，从所述预设圆周路径中截取所述参考路径的起点到终点之间的路径作为所述参考路径。
  5. 根据权利要求2所述的程控设备，其中，所述控制器被进一步配置成采用如下方式获取所述相似度：
    获取多个相似度训练数据，每个所述相似度训练数据包括用于训练的样本滑动路径、样本参考路径以及二者的标注相似度；
    利用多个所述相似度训练数据训练预设的深度学习模型，得到相似度模型；
    将所述滑动路径和所述参考路径输入所述相似度模型，得到所述相似度。
  6. 根据权利要求2所述的程控设备，其中，所述控制器被进一步配置成采用如下方式获取所述预设相似度阈值：
    获取疾病类型和相似度阈值之间的第一对应关系；
    基于所述患者的疾病类型和所述第一对应关系，获取所述患者的疾病类型对应的相似度阈值作为所述预设相似度阈值。
  7. 根据权利要求2所述的程控设备，其中，所述控制器被进一步配置成采用如下方式获取所述目标参数的配置参数值：
    获取所述预设圆周路径对应的所述目标参数的量程；
    基于所述参考路径与所述预设圆周路径的长度之比和所述目标参数的量程，确定所述目标参数的配置参数值。
  8. 根据权利要求4所述的程控设备，其中，所述预设圆周路径设置有至少一个刻度，所述控制器被进一步配置成采用如下方式获取所述目标参数的配置参数值：
    获取所述预设圆周路径对应的所述目标参数的量程以及所述预设圆周路径的每个刻度对应的所述目标参数的设定值；
    基于所述参考路径的终点最接近的刻度对应的所述目标参数的设定值，确定所述目标参数的配置参数值。
  9. 根据权利要求7或8所述的程控设备，其中，所述控制器采用如下方式获取所述预设圆周路径对应的所述目标参数的量程：
    获取关联参数的配置参数值和所述预设圆周路径对应的所述目标参数的量程的第二对应关系，所述关联参数为所述刺激器的参数中所述目标参数以外的一个或多个参数；
    基于关联参数的配置参数值和所述第二对应关系，获取所述目标参数的量程。
  10. 根据权利要求8所述的程控设备，其中，所述预设圆周路径沿自身的顺时针方向依次设置有N个刻度，第k个刻度对应的所述目标参数的设定值和第k-1个刻度对应的所述目标参数的设定值之间的差值小于第k+1个刻度对应的所述目标参数的设定值和第k个刻度对应的所述目标参数的设定值之间的差值，N为大于2的整数，k为大于1小于N的整数。
  11. 根据权利要求2所述的程控设备，其中，所述控制器还被配置成：
    当检测到所述滑动路径的任意一个轨迹点的位置不处于所述预设滑动区域时，不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述预设滑动区域。
  12. 根据权利要求2所述的程控设备，其中，所述控制器还被配置成：
    当所述相似度小于所述预设相似度阈值时，不做任何操作，或者提示用户重新操作，或者在所述触摸屏以闪烁的状态显示所述预设圆周路径。
  13. 根据权利要求1所述的程控设备，其中，所述目标参数为电压的脉宽参 数、幅值参数和频率参数中的任意一个。
  14. 根据权利要求1所述的程控设备，其中，所述患者的疾病类型包括癫痫、震颤、帕金森病、抑郁症、强迫症、阿尔茨海默症和药物成瘾症中的一个或多个。
  15. 一种植入式神经刺激系统，所述植入式神经刺激系统包括设置于患者体外的所述程控设备和植入于所述患者体内的刺激器；
    所述刺激器被配置成生成电刺激并向所述患者的体内组织施加所述电刺激；
    所述程控设备与所述刺激器可通信地连接，所述程控设备包括：
    触摸屏，所述触摸屏被配置成接收用户的操作；
    通信模块，所述通信模块被配置成实现所述程控设备与所述刺激器之间的数据交互；
    控制器，所述控制器分别与所述触摸屏和所述通信模块电连接，所述控制器被配置成：
    利用所述触摸屏接收滑动操作，响应于所述滑动操作，获取所述目标参数的配置参数值；
    基于所述目标参数的配置参数值，生成控制指令并发送至所述刺激器，以使所述刺激器根据所述控制指令生成所述电刺激。
PCT/CN2022/125078 2021-12-27 2022-10-13 程控设备和植入式神经刺激系统 WO2023124390A1 (zh)

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