WO2023107401A1 - Canule d'oxygénation avec circuit de mesure flexible - Google Patents
Canule d'oxygénation avec circuit de mesure flexible Download PDFInfo
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- WO2023107401A1 WO2023107401A1 PCT/US2022/051864 US2022051864W WO2023107401A1 WO 2023107401 A1 WO2023107401 A1 WO 2023107401A1 US 2022051864 W US2022051864 W US 2022051864W WO 2023107401 A1 WO2023107401 A1 WO 2023107401A1
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- Prior art keywords
- bridge section
- control unit
- patient
- frame
- film substrate
- Prior art date
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Classifications
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Definitions
- the present disclosure relates generally to medical oxygenation and related sensors. More particularly, the present disclosure relates to a respiration device with sensors for a continuous, long-term monitoring of an individual or patient, including measuring and analyzing respiratory condition.
- respiration of a person may be monitored for various reasons. For example, real-time respiration measurements may assist in real-time and/or automatic adjustments of oxygen levels. Knowledge about a patient's respiration may also assist a caregiver in assessing the patient's stability during surgery and recovery thereafter, or assist with therapy related to sleeping.
- the breathing apparatus includes a hollow frame comprising a bridge section and two supporting members, each supporting member configured to extend over an ear of a patient, the bridge section comprising a proximal portion configured to rest on a philtrum of the patient when the two supporting members of the frame are placed over each respective ear of the patient, and a distal portion extending in a lateral direction away from the proximal portion; a gas supply connector configured to provide a gas to an interior of the hollow frame, the hollow frame supplying the gas provided by the gas supply connector to at least one exit port located in the bridge section; a control unit coupled to the hollow frame; and a flexible thin-film substrate having a connector at a first end of the thin-film substrate and multiple appendages along a second end of the thin-film substrate, each appendage including a sensor at an end of the appendage, wherein the first end of the thin-film substrate is positioned within the hollow frame and is connected to the control unit by the
- FIGS. 1A, IB, and 1C depict a first example breathing device, according to various aspects of the subject technology.
- FIG. 2 depicts an example flexible thin-film electronic substrate, according to various aspects of the subject technology.
- FIG. 3 depicts a second example breathing device with a two-piece bridge section, according to various aspects of the subject technology.
- FIG. 4 depicts a third example breathing device with a two-piece bridge section, according to various aspects of the subject technology.
- FIGS. 5A and 5B depict an example bridge section according to various aspects of the subject technology.
- FIG. 6 depicts an example bridge section that is separable into two sections, according to various aspects of the subject technology.
- FIGS. 7A to 7C depict a fourth example breathing device with a two-piece bridge section, according to various aspects of the subject technology.
- FIGS. 8 A and 8B depict an example control unit, according to various aspects of the subject technology.
- FIG. 9 depicts an example control unit charging device, according to various aspects of the subject technology.
- FIG. 10 depicts an example process for constructing a breathing apparatus, according to aspects of the subject technology.
- FIG. 11 is a conceptual diagram illustrating an example electronic system for operating a breathing device, according to aspects of the subject technology.
- FIG. 12A-C depict a fifth example breathing device, according to various aspects of the subject technology.
- FIGS. 13A-B depict a sixth example breathing device, according to various aspects of the subject technology.
- FIGS. 14A-14C depict a seventh example breathing device with an adjustable portion, according to various aspects of the subject technology.
- FIGS. 15A-C depict flow data for a breathing apparatus according to aspects of the subject technology.
- FIG. 16 depicts flow data for a breathing apparatus according to aspects of the subject technology.
- FIGS. 17A-17C depict an eighth example of a breathing device, according to aspects of the subject technology.
- FIGS. 18A-18B depict a portion of FIGS. 17A-17C in more detail, according to aspects of the subject technology.
- FIGS. 19A-19C depict another example of a cannula portion of the breathing apparatus according to aspects of the subject technology.
- the subject technology includes a breathing device such as an oxygenation cannula with an integrated flexible circuit for oxygenating a patient while obtaining real-time precise measurements of the patient’s breathing.
- the disclosed breathing device includes a light-weight flexible hollow frame which attaches to the patient by way hooking around the patient's ears to provide oxygenation or other respiratory support to the patient’s airways.
- the disclosed breathing device may function similar to a nasal cannula in that it provides supplemental oxygenation without the need for an enclosed face mask, and may be disposable.
- the disclosed breathing device includes a framed support that houses a rechargeable and removable microprocessor-based control unit, and various sensors which communicate with the control unit by way of a flexible silicon circuit layer that traverses the frame.
- the breathing device is thus capable of oxygenating a patient through the nostrils while simultaneously measures breathing gas flow through the nostrils and/or mouth.
- the control unit includes a microprocessor, wireless communication equipment, and a rechargeable battery, and is removable from the disposable frame of the breathing device so that it can be reused again with a new frame.
- the control unit is further configured to communicate with an application installed on a mobile computing device such as a smart phone or tablet or laptop computer.
- data collected by the sensors may be logged by the application, which may also process the data and send instructions to the control unit for controlling the flow of gas to the patient or sensor sensitivities of the breathing device. Reuse of the control unit allows the patient connected portions of the breathing apparatus to be disposed, thereby preventing cross contamination and reducing cleaning time and overall cost of care.
- FIGS. 1A and IB depict a first example of a breathing device, according to various aspects of the subject technology.
- Breathing device 1 includes a hollow frame 2 configured to rest on a patient’s face and connect to a gas supply line 3, and which functions as a cannula for supplying the gas to a patient via dual nasal passages 4.
- Hollow cannula frame 2 may connect to gas supply line 3 via a connector 5.
- Gas supply line 3 may further connect to a gas source 6, which can be for example oxygen concentrator, oxygen bottle, hospital oxygenation system or similar.
- Hollow cannula frame 2 may include a bridge section 7 configured to rest on a philtrum of the patient when frame 2 is on the face of a patient.
- bridge section 7 includes a proximal portion 8a configured to rest on a philtrum of the patient, and a distal portion 8b extending in a lateral direction away from the proximal portion 8a.
- distal portion 8b when frame 2 is placed on the patient’s face, distal portion 8b curves outward away from the philtrum and lip area, beyond or below the tip of the patient’s nose.
- Hollow cannula frame 2 provides a hollow tube for the transport of gas at least from the connector 5 through bridge section 7.
- the frame 2 is hollow.
- frame 2 may be hermetically sealed so that the gas flows from the gas source 6 to the patient without loss of pressure.
- breathing device 1 also includes a sensor body 8 which houses one or more sensors.
- these sensors may include a nasal sensor 9a (also shown in FIG. 3) configured to measure the nasal respiration flow exiting a patient’s nasal cavity, and/or an oral sensor 9b configured to measure the oral respiration flow exiting a patient’s mouth.
- Any of the nasal and oral sensors 9a, 9b can include a thermistor configured to measure a characteristic of a flow adjacent to or engaging against the thermistor.
- sensors 9a and 9b include thermistors for sensing inhalation and exhalation flows.
- the resistance of each thermistor changes proportionally to flowing gas heating or cooling down the thermistor, e.g., during inspiration and expiration.
- the nasal flow passages are separated from each other such that each nasal sensor 9a may separately identify and measure the respiration flow associated with each of the patient’s nostrils. By separately identifying respiration flow associated with each of the patient’s nostrils, potential respiratory conditions or patient’s positions can be determined. For example, a blockage of a nasal passage or the respiration device can be identified and corrected.
- an oral sensor 9b is placed on a plane that is transverse or substantially perpendicular to the nasal sensors 9a.
- sensors 9a and 9b are controlled by, and provide measurements to, a control unit 10 housed in a housing 11 attached to frame 2.
- Control unit 10 may be removably connected to housing 11 such that is replaceable, or reusable with another cannula frame 2 when the present frame is disposed.
- control unit 10 connects to sensors 9a and 9b through a hollow arm 12 of frame 2.
- frame 2 may be constructed such that respective end portions of frame 2 are molded to function as rigid or semi-rigid temple pieces 13 that rest over the patient’s ears.
- temple pieces 13 may extend to hook behind the patient’s ears, keeping the breathing device 1 in place between the nose and mouth on patient’s upper lip, when placed on the patient’s face.
- FIG. 1C depicts a similar embodiment to FIGS. 1A-1B, having the addition of a control unit 2100 having a battery, processor and an O2 control valve. More specifically, the O2 control valve enables gas or O2 delivery from the 02 line 2003 to the patient’s airways during inspiration and stops gas or O2 delivery from the 02 line 2003 to the patient’s airways during expiration.
- a control unit 2100 having a battery, processor and an O2 control valve. More specifically, the O2 control valve enables gas or O2 delivery from the 02 line 2003 to the patient’s airways during inspiration and stops gas or O2 delivery from the 02 line 2003 to the patient’s airways during expiration.
- FIG. 2 depicts an example flexible thin- film electronic substrate 15, according to various aspects of the subject technology.
- Flexible thin-film electronic substrate 15 provides an electro conductive pathway for the transmission of electronic communication between various locations along the substrate.
- Substrate 15 is flexible (e.g. stretchable, bendable and/or compressible).
- the substrate 15 can be made of one or more flexible electrically conductive layers, including a flexible elastomer or elastomeric material, a plastic, or a combination thereof.
- to substrate material may include a silicon or may include, for example, polymers not limited to polyimide polymer (e.g.
- substrate 15 is depicted as a long flat strip, it may take on a different profile.
- substrate 15 may have a square or rectangular profile, or may be round or ovoid, or the like.
- Substrate 15 also termed a “conduit” or “circuit” herein, as described herein, may include wires or traces or other means for the transfer of electricity or electrical signals, but is not itself a traditionally gauged wire. In some implementations, one or more wires may supplement or replace substrate 15 or a portion of substrate 15.
- circuitry such as a laminated battery, a set of microchips, a sensor 9a, 9b, a sensor hub, antenna, and an assortment of integrated passive devices (IPD) may be applied, secured, embedded or otherwise affixed to substrate 15.
- substrate 15 may be electroplated or filled through sputtering or other known technique to create electrical connections, pads, and/or traces.
- One or more conductive layers can be patterned and an overlay (e.g. non-conductive polymer) can be applied to the outer surface of each conductive layer.
- the depicted flexible thin-film electronic substrate 15 includes a longer portion 16 extending from a first end 17 to a second end 18 that includes multiple appendages 19 disposed along the second end 18.
- each appendage 19 may terminate at a sensor 9a, 9b.
- a sensor may be embedded on an appendage 19.
- the chemical characteristics of the appendage 19 itself, or of the substrate 15, or a portion of substrate 15, may operate as a sensor.
- each sensor 9a, 9b may be a thermistor, and the appendage or portion thereof may be a thermally conductive material that changes its impedance responsive to a change in temperature.
- FIG. 3 depicts a second example breathing device with a two-piece bridge section, according to various aspects of the subject technology.
- proximal portion 8a of bridge section 7 may be separable from frame 2, but configured to interconnect with frame 2 to form a single unit.
- the second end 18 of the electronic substrate 15 is routed through proximal portion 8a and each appendage 19 passes through an opening in a wall of the bridge section 7 to provide each respective embedded sensor to an exterior of the bridge section.
- First end 17 of the electronic flex circuit is passed through an opening of frame 2 located at an interconnection point between bridge section 7 and frame 2 (not shown), and is routed through supporting member to connect to control unit 10.
- proximal portion 8a of bridge section 7 may be attached to distal portion 8b, as shown (20).
- FIG. 4 depicts a third example breathing device with a two-piece bridge section, according to various aspects of the subject technology.
- breathing device 1 includes two continuous hollow frame sections 2a, 2b.
- Each frame section includes a hollow supporting arm 12 configured to be placed over a respective ear of a patient.
- a first of the frame sections may include or may be contiguous with the proximal portion 8a of bridge section 7, and the other section may include the distal portion 8b of bridge section 7.
- a hollow chamber or cavity traverses each frame section through the corresponding portion of the bridge.
- the hollow chamber or cavity of the frame section connected to gas supply connector is configured to supply the gas to ports or openings of the nasal passages 4.
- the hollow chamber or cavity of the frame section connected to control unit 10 is configured to support the electronic substrate 15.
- a hollow chamber may both support the substrate 15 (or portion thereof) and be a conduit for the gas supply.
- FIGS. 5A and 5B depict an example bridge section according to various aspects of the subject technology.
- FIG. 5A depicts flow of gases relative to bridge section 7, a patient’s nares, and the ambient environment. Arrows 22 illustrate a portion of nasal respiration flow expelled from bridge section 7 to a patient’s nares.
- Proximal portion 8a and distal portion 8b collectively form a contiguous cavity 24 (dotted line) so that the openings of nasal passages 4 are enclosed within the cavity.
- proximal portion 8a also contain sensors 9a, or similar means, placed by the nasal passages 4, also enclosed inside cavity 24, to measure breathing gas air flow between the nostrils and the ambient flowing through the cavity 24. Sensor 9b is placed in the middle of the opening to measure breathing gas flow between the mouth and ambient air.
- Circles 26 and their corresponding arrows illustrate a portion and flow of ambient gas directed from the ambient environment toward each nasal sensor 9a during inspiration.
- FIG. 5B depicts an example bridge section, including a pulse oximetry sensor, according to various aspects of the subject technology.
- Bridge section 7 may include a pulse oximetry sensor 28 configured to measure oxygen level (oxygen saturation) of the blood by passing wavelengths of light through the skin proximate to the philtrum or lip of the patient to a photodetector.
- sensor 28 may include two LEDs that emit light at different wavelengths. The light traverses through the tissue and is reflected from the bone. Reflected light traverses through the tissue again, and the detectors detect the reflected light.
- the depicted sensor 28 may be coupled to a side of the proximal portion 8a nearest the patient’s face so that sensor 9a may read the patient’s oxygen saturation (SaO2) directly from the philtrum area of the patient.
- SaO2 oxygen saturation
- FIG. 6 depicts an example bridge section that is separable into two sections, according to various aspects of the subject technology.
- Bridge section 7 includes a proximal portion 8a configured to rest on a philtrum of the patient when the two supporting members 12a, 12b, of the breathing device 1 are placed over each respective ear of the patient, and a distal portion 8b extending in a lateral direction away from the proximal portion 8a.
- breathing device 1 may include two sections: a first frame section which includes or may be contiguous with the proximal portion 8a of bridge section 7, and the other section which includes the distal portion 8b of bridge section 7.
- first or proximal section 8a and second or distal section 8b are configured to interconnect with each other to form a single bridge section 7.
- the first frame section 2a comprises a first single contiguous chamber extending through a first supporting member 12a of the two supporting members and through the proximal portion 8a of the bridge section 7, and the second frame section 2b comprises a second single contiguous chamber extending through a second supporting member 12b of the two supporting members and through the distal portion 8b of the bridge section 7.
- the gas supply connector 5 is connected to an end of the second supporting member 12b and the gas provided by the gas supply connector is provided to the at least one exit port of the nasal passages 4.
- electronic substrate 15 traverses the first supporting member 12a to the proximal portion 8a of the bridge section 7 via a single contiguous chamber.
- flexible electronic substrate 15 traverses inside a cavity within the first supporting member 12a extending through the proximal portion 8a and through nasal guides 30 to cavity 24.
- an end of electronic substrate 15 passes through an opening in a wall of the bridge section.
- nasal guides 30 form the opening through the wall and extend out away from the wall of the bridge section to provide the sensors embedded within or affixed to the substrate at a position near the exit ports of the nasal passages 4 and thus at a desirable position near a patient’s nostrils to sense a characteristic of the patient’s respiration.
- Second supporting member 12b forms single a conduit to tubular nasal ducts formed by the nasal passages 4 to deliver oxygen to patient’s airways.
- Section 2a connects with section 2b at respective connection points 31 by way of respective male-female connectors 32 and 33.
- Thermistors 40, 41 may be located into the ends of an electronic substrate 15.
- Electronic substrate 15 can also contain thermistor 42 to measure the skin temperature from the patient’s upper lip and the pulse oximetry sensor 28 to measure oxygen saturation and pulse rate through the patient’s upper lip or philtrum area.
- Electronic substrate 15 may include electrical wires or traces (not shown in figure) that electrically connect the thermistors with the electrical contacts of a connector at the first end 17 of electronic substrate 15.
- the electronic flex circuit is located inside the cavity in the first supporting member 12a extending through the proximal portion 8a and through the nasal guides 30 to cavity 24. Flexible circuit and the corresponding thermistors are electrically connected with the control unit 10 (e.g. a central processing unit connected to connector housing 11). Control unit 10 receives electrical signals from the thermistors and the pulse oximetry sensor 28 or any other similar sensors connected on the electronic substrate 15.
- FIGS. 7A to 7B depict a fourth example breathing device with a two-piece bridge section, according to various aspects of the subject technology.
- exit ports or openings of the nasal passages 4 are located in the proximal portion 8a of the bridge section 7 such that the gas provided by the gas supply connector is provided to at least one exit port of the nasal passages 4 via a single contiguous chamber from connector 5 to the exit port(s) of the nasal passages 4.
- a sensor section 35 of breathing device 1 that includes electronic substrate 15 may be coupled to the first section, as depicted in FIG. 7C.
- Substrate 15 may be embedded within the sensor section 35 or be part of sensor section 35.
- the outer wall of sensor section 35 may be constructed of materials which implement substrate 15.
- FIGS. 12A-C depict a fifth example of a breathing device, according to various aspects of the subject technology.
- Breathing device 1001 includes a hollow frame 1002 configured to rest on a patient’s face and connect to a gas supply line 1003, which functions as a cannula for supplying gas to a patient via openings 1012.
- Hollow cannula frame 1002 may connect to a gas supply line 1003 via a connector (not shown).
- oxygen flows through gas supply line 1003, which may be in the form of a tube, through a valve 1005, into a bridge section 1007 and through a cavity portion 1011, located under the isthmus, and openings 1012, located under the left and right nostrils respectively and through the nostrils and into the patient’s airways upon inhalation.
- gas supply line 1003 which may be in the form of a tube
- valve 1005 into a bridge section 1007 and through a cavity portion 1011, located under the isthmus
- openings 1012 located under the left and right nostrils respectively and through the nostrils and into the patient’s airways upon inhalation.
- the valve 1005 is electrically connected to a control unit 1010 through an electrical flex circuit 1015.
- the control unit 1010 contains hardware, software and means to regulate the valve 1005.
- the valve 1005 is opened to deliver oxygen to patient during inhalation and closed to prevent the flow of oxygen when the patient exhales.
- the inhalation and exhalation is detected with thermistors 1009, which electrically connect with the control unit 1010 through the electrical flex circuit 1015.
- Cavity portion 1011 is formed of two half pipes 1014 and 1016, having concave sides positioned facing one another with an opening 1018 between the half pipes 1014, 1016 and channel 1017.
- the concave structure of the cavity portion 1011 and the channel 1017 enable the oxygen to be dispersed between both sides of the half pipes 1014 and 1016, and then flow directly into the left and right patient nostrils.
- a portion of the breathing device 1001 is disposable and a portion a reusable.
- the control unit 1010 may include the valve 1005, creating a reusable portion which can then be attached to a disposable portion including the bridge section 1007, electrical flex circuit 1015, and cannula frame 1002.
- FIGS. 13A-B depict a sixth example of a breathing device, according to various aspects of the subject technology.
- Breathing device 1101 includes a hollow frame 1102 configured to rest on a patient’s face and connect to a gas supply line 1103, which functions as a cannula for supplying gas to a patient.
- Hollow cannula frame 1102 may connect to a gas supply line 1103 via a connector (not shown).
- oxygen flows through gas supply line 1103, which may be in the form of a tube, through a valve 1105, into a bridge portion 1107 and into cavities 1112 and 1113 under the left and right nostrils respectively and into the patient’s airways upon inhalation.
- the valve 1105 is electrically connected to a control unit 1110 through an electrical flex circuit 1115.
- the control unit 1110 contains hardware, software and means to regulate the valve 1105.
- the valve 1105 is opened to deliver oxygen to patient during inhalation and closed to prevent the flow of oxygen when the patient exhales.
- the inhalation and exhalation is detected with thermistors 1109, which electrically connect with the control unit 1110 through the electrical flex circuit 1115.
- Bridge portion 1107 includes multiple openings 1111 disposed along surfaces thereof.
- the openings 1111 may be positioned generally perpendicular to the direction of patient inhalation and exhalation. Further, the openings 1111 may generally reside in a plane parallel to the thermistors. Openings 1111 are illustrated as spherical in shape, however other shapes are envisioned and within the purview of those skilled in the art. As oxygen flows through the openings 1111, the oxygen is directed to cavities 1112 and 1113 creates a micro atmosphere or oxygen curtain under the nostrils, which is delivered into the airways when the patient inhales. Further, oxygen may be delivered during inhalation and exhalation of the patient.
- a portion of the breathing device 1101 is disposable and a portion a reusable.
- the control unit 1110 may include the valve 1105, creating a reusable portion which can then be attached to a disposable portion including the bridge portion 1107, electrical flex circuit 1117, and cannula frame 1102.
- FIGS. 17A- 17B and FIGS. 18A- 18B depict another example of a breathing device, according to various aspects of the subject technology, with differences described in more detail.
- FIGS. 17A and 18A illustrate an exploded view of the breathing device 3001 and FIG. 17B and 18B illustrate an assembled view of the breathing device 3001.
- Breathing device 3001 includes a cannula frame 3002 configured to rest on a patient’s face and the frame 30002 connects to a gas supply line 3003.
- Cannula frame 3002 provides supports 3002a (shown in FIGS. 18A, 18B) for retaining the gas supply line 3003, which may be in the form of a snap or friction fit.
- Gas supply line 3003 may further connect to a gas source (not shown), which can be for example, an oxygen concentrator, oxygen bottle, hospital oxygenation system or similar.
- a gas source (not shown), which can be for example, an oxygen concentrator, oxygen bottle, hospital oxygenation system or similar.
- Cannula frame 3002 may include a bridge section 3007 configured to rest on a philtrum of the patient when frame 3002 is on the face of a patient.
- Cannula frame 3002 also includes a nasal bridge portion 3100.
- the nasal bridge portion 3100 includes at least one nasal port 3104, and preferably two nasal ports 3104 for insertion into or positioning adjacent a patient’s nares.
- the nasal bridge portion 3100 is connected to posts 3050 on the cannula frame 3002.
- the nasal bridge portion 3100 is made of a flexible material, such as silicone, which can easily slide over, and the end portions can be temporarily expanded to fit on the posts 3050. Once released, the silicone material will tightly fit over the posts 3050, however glues, adhesives, or other solvent welding techniques can be employed to provide enhanced security of the nasal bridge portion 3100 to the posts 3050.
- breathing device 3001 also includes an electronic substrate 3040 which houses one or more sensors.
- the electronic substrate functions similar to electronic substrate 15 described herein.
- the sensors may include nasal thermistors 3009a configured to measure the nasal respiration flow exiting a patient’s nasal cavity, and/or an oral sensor 3009b configured to measure the oral respiration flow exiting a patient’s mouth.
- the depicted electronic flex circuit 3040 also includes a pulse oximetry sensor 3028, according to various aspects of the subject technology.
- the pulse oximetry sensor 3028 is configured to measure oxygen level (oxygen saturation) of the blood by passing wavelengths of light through the skin proximate to the philtrum or lip of the patient to a photodetector.
- sensor 3028 may include two LEDs that emit light at different wavelengths. The light traverses through the tissue and is reflected from the bone. Reflected light traverses through the tissue again, and the detectors detect the reflected light.
- the depicted sensor 3028 may be coupled to a side of a proximal portion nearest the patient’s face so that sensor 3028 may read the patient’s oxygen saturation (SaO2) directly from the patients face.
- a sensor cover 3029 may snap fit over the sensor 3028 to protect the sensor and provide patient comfort.
- the sensor cover 3029 may include a cut out or window portion such that the sensor 3028 may directly contact the patient’s skin while protecting the electronics.
- the sensor cover 3029 may comprise silicone.
- the sensor cover 3029 may also be configured to receive other components of the breathing device 3001, such as the nasal cannula 3004.
- a sensor of the electronic flex circuit 3040 can be configured to measure oxygen gas flow from the nasal passages 4. The oxygen gas flow can be measured using any of the sensors 3009a, 3009b.
- a branch or finger can extend from the electronic flex circuit. In some examples, the branch or finger of the electronic flex circuit can extend from portion(s) of the thin-film substrate forming the appendage of any of the first and second sensors 3009a.
- the oxygen gas flow exiting from the gas openings of nasal passages 4 can be measured using the branch or finger extending from the electronic flex circuit.
- the branch or finger can be shaped so that a portion or distal end of the branch or finger is adjacent to or extends into a fluid flow pathway extending from the gas openings of nasal passages 4 toward the patient when the breathing device is worn by a patient.
- the oxygen gas flow can be measured within the oxygen gas cannula formed by the hollow arm 12, the frame 2, or another portion of the breathing device.
- the oxygen gas flow can be measured within the oxygen gas cannula by a sensor extending from or coupled to the electronic flex circuit.
- a sensor for measuring the oxygen gas flow can be positioned within the oxygen gas cannula.
- the breathing device of the present disclosure can be used to monitor the flow of oxygen from the mask, and can be used to determine if a change to the oxygen gas flow has occurred.
- a change to the oxygen gas flow can occur intentionally or unintentionally, such as closing or changing the value of oxygen flow from a source of oxygen or the oxygen tubing accidentally disconnected from the source of oxygen.
- the breathing device in some embodiments, can create or send an alarm signal if an unintentional change to oxygen gas flow has occurred.
- features of the present disclosure can minimize risks associated with unintentional changes to gas delivery for a patient.
- sensors 3009a, 3009b, and 3028 are controlled by, and provide measurements to, a control unit 3010 housed in a housing 3011 attached to frame 3002.
- Electronic flex circuit 3040 may include electrical wires or traces (not shown in figure) that electrically connect the thermistors as the sensors 3009a, 3009b, with the electrical contacts of a connector at one end of electronic flex circuit 3040.
- Control unit 3010 may be removably connected to control unit housing 3011 such that is replaceable, or reusable with another cannula frame 3002 when the present frame is disposed.
- the electronic flex circuit 3040 is connected to the control unit 1010 by passing a first end 3040a of the electronic substrate 3015 through an opening of frame 3002 and routing through supporting member to connect to control unit 3010.
- the first end 3040a of the electronic flex circuit can include hooks for attaching to the housing 3011 and connecting the electronic substrate 3015 with the control unit 3010.
- the frame 3002 may be constructed such that respective end portions of frame 3002 are molded to function as rigid or semi-rigid temple pieces 3013 that rest over the patient’s ears.
- temple pieces 3013 may extend to hook behind the patient’s ears, keeping the breathing device 3001 in place between the nose and mouth on patient’s upper lip, when placed on the patient’s face.
- flexible loops 3014 may be attached to the frame or otherwise molded thereon.
- FIG. 17C illustrates elastic flexible loops 3014 which may be looped over the patient’s ears, in a manner similar to a surgical facemask.
- FIGS. 19A and 19B illustrate different diameter nasal bridge portions 3100a, 3100b to deliver oxygen to a patient’s airways using the breathing device 3001.
- the larger diameter bridge portion as illustrated in FIG. 19A is one example of a “high flow” (HF) oxygen nasal cannula.
- the nasal bridge portion has a larger cross-sectional diameter dhfi for the nasal ports 3104a in addition to a larger cross-sectional diameter of the nasal bridge portion frame dhf2.
- a “low flow” (LF) oxygen nasal bridge portion is illustrated in FIG. 19B.
- the nasal bridge portion 3104b has a smaller cross-sectional nasal port diameter din in addition to a smaller cross-sectional diameter nasal bridge portion frame die.
- Both the LF and HF nasal bridge portion configurations comprise a flexible material such as silicone. Both LF and HF nasal bridge portions are configured to connect to the cannula frame 3002, as shown for example in FIG. 19C.
- Breathing device frame includes posts 3050 which extend towards the patient’s midline. The posts 3050 are sized and shaped such that both the LF and HF nasal bridge portions can securely connect to the cannula frame 3002. In other embodiments, the posts can be sized and shaped to receive either one or another of a LF or HF nasal bridge portion. It should be noted that prior to attaching to the frame 3002, sensor cover 3029 is received within one end of the nasal bridge portion. The nasal bridge portion retains the sensor cover 3029 in place.
- the cross-sectional diameter of the nasal port(s) 3014b and the nasal bridge portion frame dis may be smaller to accommodate oxygen delivery rates of 0-6L/min.
- a cross-sectional inner diameter of the nasal port 3104b may be from about 1 -5 mm, in embodiments, 2-4 mm, and in further embodiments, 3 mm.
- the nasal bridge portion frame die which supplies oxygen to the nasal port(s) may also be smaller and closer in size to the nasal port diameter.
- cross-sectional inner diameter of the nasal port(s) 3104a may be larger to accommodate oxygen delivery rates of up to 60L/min, in embodiments 30-60L/min, in other embodiments, 6L/min up to 60L/min.
- HF for an infant may be 6L/min while HF for an adult may be 60L/min.
- HF rates may vary depending on patient size.
- Cross-sectional diameter of the nasal port(s) 3104a and nasal bridge portion frame dhn may also be larger to accommodate higher flow rates.
- nasal port(s) for HF may be from about 4-6mm, and in embodiments, about 5mm in inner diameter.
- any of the embodiments described herein may have larger or smaller diameter nasal port(s) and cannulas such that the device can accommodate either LF or HF. It should be noted for any of the embodiments described herein, the use or one or two nasal ports is envisioned. Further, nasal ports may vary in shape, size and dimension to optimize oxygen flow to the patient.
- FIGS. 8 A and 8B depict an example control unit 10, according to various aspects of the subject technology.
- FIG. 8A depicts a control unit housing 1 1 affixed to the end of a arm 12.
- housing 11 may be adjacent to a respective temple piece 13 which, as depicted, may be configured to hook behind the patient’s ears.
- FIG. 8B depicts a printed circuit board (PCB) 36 with a microprocessor and related circuitry for operating control unit 10.
- Control unit 10 may include a microprocessor, a communication device, and a battery.
- a connector port 37 may be configured to allow electronic substrate 15 to removably plug-in to and communicate with control unit 10.
- control unit 10 can contain accelerometer and/or position sensor (not shown in figures) to measure patient’s head posture, movement, activity, position, walking, falling etc.
- the processor of control unit 10 may process and calculate respiration measurement values.
- the battery may be a rechargeable battery.
- Communication device may be a radio frequency transceiver to enable patient mobility and wireless operation, data transfer wirelessly to the host monitor to show the measured values for the care giver.
- the battery may power the microprocessor, communication device, and each sensor 9a, 9b of the electronic substrate 15.
- Radio frequency transceiver such as Bluetooth or WLAN, also enable measuring the location of the patient.
- Control unit 10 measures patient’s breathing gas flow and calculates respiration rate, and may also detect the time of inspiration and expiration from the breathing waveform. Control unit 10 may connect to a remote application and provide to that application respiration data measured from sensors 9 in real time. In some implementations, control unit may pair with or communicate with an oxygen delivery device to control the oxygen delivery in real time. For example, control unit 10 may instruct the delivery device to deliver oxygen to a patient’s airways during inspiration only. Control unit 10 may increase or decrease oxygenation flow and concentration remotely by controlling the valve depending on the need of oxygenation.
- the electronic flex circuit includes first and second sensors 3009a.
- a thermistor of a first sensor 3009a can measure a temperature change, such as a change in temperature caused by oxygen gas flow, which can be used to determine a change that is proportional to oxygen gas flow speed. This measurement is relative, as the temperature of oxygen gas causes an offset to measured signal.
- a thermistor of a second sensor 3009a can be used to determine an absolute oxygen gas flow speed.
- Control unit 10 may detect and communicate all patient actions back to a remove application.
- Control unit 10 (or the remote application) may record breathing measurements, and may correlate breath actions by the patient (e.g. a respiration rate) with a stored treatment plan.
- a caregiver may connect to the control unit 10 to view the log file when patient visits the caregiver’s office and determine whether the patient has followed the treatment plan or what were the deviations to the plan.
- FIGS. 14A-C depict another, seventh embodiment of a breathing device having a control unit 1210, according to various aspects of the subject technology.
- Control unit 1210 is similar to control unit 10 and functions as described herein with any differences are described below.
- FIG. 14 depicts a control unit housing 1211 affixed to the end of a support arm 1212.
- housing 1211 may be adjacent to a respective temple piece 1213 which, as depicted, may be configured to hook behind the patient’s ears.
- Temple piece 1213 may be adjustable to fit a specific patient. Adjustability may be controlled via a ratcheting mechanism 1214, or similar.
- Control unit 1210 may include a microprocessor, a communication device, and a battery.
- the housing 1211 may be a connector port 1237 which can be configured to allow flexible circuit to removably plug-in to and communicate with control unit 1210.
- the connector port 1237 includes tabs 1237a which enable entry and removal of the control unit 1210.
- FIG. 9 depicts an example control unit charging device, according to various aspects of the subject technology.
- control unit 10 may be replaced by a caregiver or the patient according to a treatment plan, or when a currently used control unit 10 experiences a failure or is required to be removed to upload data or to recharge the battery.
- Charging device 38 is provided to charge more than one control unit 10 at a time.
- Charging device 38 may be powered by a power adapter or may be powered by USB power.
- charging device 38 may upload or download data to and from a remote system using a USB or similar data cable.
- data transfer may be wireless.
- FIG. 10 depicts an example process for constructing a breathing device 1, according to aspects of the subject technology.
- the various blocks of example process 100 are described herein with reference to FIGS. 1-9, and the components and/or processes described herein. In some implementations, one or more of the blocks may be implemented apart from other blocks, and by one or more different processors or devices. Further for explanatory purposes, the blocks of example process 100 are described as occurring in serial, or linearly. However, multiple blocks of example process 100 may occur in parallel. In addition, the blocks of example process 100 need not be performed in the order shown and/or one or more of the blocks of example process 100 need not be performed.
- a hollow frame comprising a bridge section and two supporting members is constructed with each supporting member configured to extend over an ear of a patient.
- the bridge section is divided into a proximal portion configured to rest on a philtrum of the patient when the two supporting members of the frame are placed over each respective ear of the patient, and a distal portion extending in a lateral direction away from the proximal portion.
- the bridge section divides (or splits) the hollow frame into to two bridge segments at location corresponding to the philtrum of the wearer of the frame.
- the proximal portion and the distal portion start on each side connected to a respective supporting member, and then diverge further from each other and become the most spaced apart at a location corresponding to the wearer’s nose.
- the distal portion is curved (e.g. an arc) with the space between the distal portion and the proximal portion becoming largest at the apex of the curve (or arc) at the location corresponding to the wearer’s nose.
- one or both of the distal and proximal portions are hollow, as are the supporting members, and one or both of the distal and proximal portions may form a contiguous hollow chamber with a corresponding supporting member, as depicted in the various figures.
- a gas supply connector is coupled to the hollow frame.
- the gas supply connector configured to provide a gas to an interior of the hollow frame
- the hollow frame is configured to supply the gas provided by the gas supply connector to at least one exit port located in the bridge section. According to various implementations there are two exit ports, one for each nostril of a patient.
- step 103 a control unit is coupled to the hollow frame.
- a flexible thin-film substrate having a connector at a first end of the thin-film substrate and multiple appendages along a second end of the thin-film substrate is inserted within at least a portion of the hollow frame.
- Each appendage includes a sensor at an end of the appendage.
- step 105 the first end of the thin-film substrate is connected to the control unit by the connector.
- the thin-film substrate traverses a portion of the hollow frame between the control unit and the bridge section, and the second end traverses an interior of the bridge section and each appendage of the multiple appendages passes through an opening in a wall of the bridge section to provide each respective embedded sensor to an exterior of the bridge section.
- the thin-film substrate is configured to provide electrical communication between each sensor and the control unit.
- FIG. 11 is a conceptual diagram illustrating an example electronic system 800 for operating a breathing device, according to aspects of the subject technology.
- Electronic system 800 may be a computing device for execution of software associated with one or more portions or steps of process 700, or components and processes provided by FIGS. 1-10.
- Electronic system 800 may be representative, in combination with the disclosure regarding FIGS. 1-10, ofthe control unit 10.
- electronic system 800 may also represent a computing device connected to control unit 10.
- electronic system may be a personal computer or a mobile device such as a smartphone, tablet computer, laptop, PDA, an augmented reality device, a wearable such as a watch or band or glasses, or combination thereof, or other touch screen or television with one or more processors embedded therein or coupled thereto, or any other sort of computer-related electronic device having network connectivity.
- a personal computer or a mobile device such as a smartphone, tablet computer, laptop, PDA, an augmented reality device, a wearable such as a watch or band or glasses, or combination thereof, or other touch screen or television with one or more processors embedded therein or coupled thereto, or any other sort of computer-related electronic device having network connectivity.
- Electronic system 800 may include various types of computer readable media and interfaces for various other types of computer readable media.
- electronic system 800 includes a bus 808, processing unit(s) 812, a system memory 804, a read-only memory (ROM) 810, a permanent storage device 802, an input device interface 814, an output device interface 806, and one or more network interfaces 816.
- ROM read-only memory
- electronic system 800 may include or be integrated with other computing devices or circuitry for operation of the various components and processes previously described.
- Bus 808 collectively represents all system, peripheral, and chipset buses that communicatively connect the numerous internal devices of electronic system 800. For instance, bus 808 communicatively connects processing unit(s) 812 with ROM 810, system memory 804, and permanent storage device 802.
- processing unit(s) 812 retrieves instructions to execute and data to process in order to execute the processes of the subject disclosure.
- the processing unit(s) can be a single processor or a multi-core processor in different implementations.
- ROM 810 stores static data and instructions that are needed by processing unit(s) 812 and other modules of the electronic system.
- Permanent storage device 802 is a read- and- write memory device. This device is a non-volatile memory unit that stores instructions and data even when electronic system 800 is off.
- Some implementations of the subject disclosure use a mass-storage device (such as a magnetic or optical disk and its corresponding disk drive) as permanent storage device 802.
- system memory 804 is a read-and-write memory device. However, unlike storage device 802, system memory 804 is a volatile read-and-write memory, such a random access memory. System memory 804 stores some of the instructions and data that the processor needs at runtime. In some implementations, the processes of the subject disclosure are stored in system memory 804, permanent storage device 802, and/or ROM 810. From these various memory units, processing unit(s) 812 retrieves instructions to execute and data to process in order to execute the processes of some implementations.
- Bus 808 also connects to input and output device interfaces 814 and 806.
- Input device interface 814 enables the user to communicate information and select commands to the electronic system.
- Input devices used with input device interface 814 include, e.g., alphanumeric keyboards and pointing devices (also called “cursor control devices”).
- Output device interfaces 806 enables, e.g., the display of images generated by the electronic system 800.
- Output devices used with output device interface 806 include, e.g., printers and display devices, such as cathode ray tubes (CRT) or liquid crystal displays (LCD). Some implementations include devices such as a touchscreen that functions as both input and output devices.
- CTR cathode ray tubes
- LCD liquid crystal displays
- bus 808 also couples electronic system 800 to a network (not shown) through network interfaces 816.
- Network interfaces 816 may include, e.g., a wireless access point (e.g., Bluetooth or WiFi) or radio circuitry for connecting to a wireless access point.
- Network interfaces 816 may also include hardware (e.g., Ethernet hardware) for connecting the computer to a part of a network of computers such as a local area network (“LAN”), a wide area network (“WAN”), wireless LAN, or an Intranet, or a network of networks, such as the Internet.
- LAN local area network
- WAN wide area network
- Internet LAN
- Any or all components of electronic system 800 can be used in conjunction with the subject disclosure.
- Some implementations include electronic components, such as microprocessors, storage and memory that store computer program instructions in a machine- readable or computer-readable medium (alternatively referred to as computer-readable storage media, machine-readable media, or machine-readable storage media).
- electronic components such as microprocessors, storage and memory that store computer program instructions in a machine- readable or computer-readable medium (alternatively referred to as computer-readable storage media, machine-readable media, or machine-readable storage media).
- Such computer-readable media include RAM, ROM, read-only compact discs (CD-ROM), recordable compact discs (CD-R), rewritable compact discs (CD-RW), read-only digital versatile discs (e.g., DVD-ROM, dual-layer DVD-ROM), a variety of recordable/rewritable DVDs (e.g., DVD-RAM, DVD-RW, DVD+RW, etc.), flash memory (e.g., SD cards, mini-SD cards, micro-SD cards, etc.), magnetic and/or solid state hard drives, read-only and recordable Blu-Ray® discs, ultra density optical discs, any other optical or magnetic media, and floppy disks.
- RAM random access memory
- ROM read-only compact discs
- CD-R recordable compact discs
- CD-RW rewritable compact discs
- read-only digital versatile discs e.g., DVD-ROM, dual-layer DVD-ROM
- flash memory e.g., SD cards, mini
- the computer-readable media can store a computer program that is executable by at least one processing unit and includes sets of instructions for performing various operations.
- Examples of computer programs or computer code include machine code, such as is produced by a compiler, and files including higher-level code that are executed by a computer, an electronic component, or a microprocessor using an interpreter.
- ASICs application specific integrated circuits
- FPGAs field programmable gate arrays
- integrated circuits execute instructions that are stored on the circuit itself.
- FIGS. 15A-C illustrate waveforms for low flow (LF) breathing signals.
- LF low flow
- breathing function is measured from the left nostril (L), mouth (M), and right nostril (R).
- the figures also illustrate an average waveform (A) and the winner channel (W) which illustrates the waveform with the best signal to noise ratio.
- Inhalation and exhalation are measured before, during and after oxygen flow to the patient.
- oxygen flow is measured at OL/min for about 2.5 breaths, then oxygen flow turns on to 1 OL/min while breathing is measured.
- the waveform transitions back to the original waveform having larger amplitude, even though oxygen is flowing.
- FIG. 15B illustrates similar displayed values of L, M, R, A, and W for a 3mm cannula.
- Oxygen is initially provided at OL/min then is increased to 20L/min. Once oxygen is flowing, the amplitude of the wavelength is decreased temporarily and after 3 breaths, the waveform starts to transition back to the normal or larger wavelength signals recorded by the nose and mouth.
- Breath 4 illustrates a larger wavelength than breath 3, and if timepoints were to be taken out further, one would envision the wavelengths would normalize to their initial, higher amplitude wavelength.
- 15C includes wavelength displays wherein oxygen flow is initially provided at 20L/min and then oxygen flow is switched off to OL/min. The amplitude change is initially visible and if breathing were to be monitored over then next several breaths, the amplitude of the waveform would be observed decreasing.
- Figure 16 includes a comparison chart between a 3mm cannula and a 5mm cannula.
- the upper portion of the chart illustrates for a 3mm cannula at flow of 20L/min, the flow is converted to a volume of gas using length (L), width (W) and height (H).
- the area of the 3 mm cannula can be calculated, knowing the radius of a 3 mm cannula is 1.5 mm.
- the gas speed is 47.2 m/s.
- a larger diameter cannula at 5mm having 55L/min of oxygen flow translates to a gas speed of 46.7 m/s.
- the waveforms as illustrated herein may also be similar.
- the terms “computer,” “server,” “processor,” and “memory” all refer to electronic or other technological devices. These terms exclude people or groups of people.
- display or displaying means displaying on an electronic device.
- computer readable medium and “computer readable media” are entirely restricted to tangible, physical objects that store information in a form that is readable by a computer. These terms exclude any wireless signals, wired download signals, and any other ephemeral signals.
- implementations of the subject matter described in this specification can be implemented on a computer having a display device, e.g., a CRT (cathode ray tube) or LCD (liquid crystal display) monitor, for displaying information to the user and a keyboard and a pointing device, e.g., a mouse or a trackball, by which the user can provide input to the computer.
- a display device e.g., a CRT (cathode ray tube) or LCD (liquid crystal display) monitor
- a keyboard and a pointing device e.g., a mouse or a trackball
- Other kinds of devices can be used to provide for interaction with a user as well; e.g., feedback provided to the user can be any form of sensory feedback, e.g., visual feedback, auditory feedback, or tactile feedback; and input from the user can be received in any form, including acoustic, speech, or tactile input.
- a computer can interact with a user by sending documents to and receiving documents from
- Implementations of the subject matter described in this specification can be implemented in a computing system that includes a back end component, e.g., as a data server, or that includes a middleware component, e.g., an application server, or that includes a front end component, e.g., a client computer having a graphical user interface or a Web browser through which a user can interact with an implementation of the subject matter described in this specification, or any combination of one or more such back end, middleware, or front end components.
- the components of the system can be interconnected by any form or medium of digital data communication, e.g., a communication network. Examples of communication networks include a local area network (“LAN”) and a wide area network (“WAN”), an internetwork (e.g., the Internet), and peer-to-peer networks (e.g., ad hoc peer-to-peer networks).
- LAN local area network
- WAN wide area network
- Internet internetwork
- peer-to-peer networks e.g.,
- the computing system can include clients and servers.
- a client and server are generally remote from each other and may interact through a communication network. The relationship of client and server arises by virtue of computer programs running on the respective computers and having a client-server relationship to each other.
- a server transmits data (e.g., an HTML page) to a client device (e.g., for purposes of displaying data to and receiving user input from a user interacting with the client device).
- client device e.g., for purposes of displaying data to and receiving user input from a user interacting with the client device.
- Data generated at the client device e.g., a result of the user interaction
- the term website may include any aspect of a website, including one or more web pages, one or more servers used to host or store web related content, etc. Accordingly, the term website may be used interchangeably with the terms web page and server.
- the predicate words “configured to,” “operable to,” and “programmed to” do not imply any particular tangible or intangible modification of a subject, but, rather, are intended to be used interchangeably.
- a processor configured to monitor and control an operation or a component may also mean the processor being programmed to monitor and control the operation or the processor being operable to monitor and control the operation.
- a processor configured to execute code can be construed as a processor programmed to execute code or operable to execute code.
- the term automatic may include performance by a computer or machine without user intervention; for example, by instructions responsive to a predicate action by the computer or machine or other initiation mechanism.
- the word “example” is used herein to mean “serving as an example or illustration.” Any aspect or design described herein as “example” is not necessarily to be construed as preferred or advantageous over other aspects or designs.
- a phrase such as an “aspect” does not imply that such aspect is essential to the subject technology or that such aspect applies to all configurations of the subject technology.
- a disclosure relating to an aspect may apply to all configurations, or one or more configurations.
- An aspect may provide one or more examples.
- a phrase such as an aspect may refer to one or more aspects and vice versa.
- a phrase such as an “implementation” does not imply that such implementation is essential to the subject technology or that such implementation applies to all configurations of the subject technology.
- a disclosure relating to an implementation may apply to all implementations, or one or more implementations.
- An implementation may provide one or more examples.
- a phrase such as an “implementation” may refer to one or more implementations and vice versa.
- a phrase such as a “configuration” does not imply that such configuration is essential to the subject technology or that such configuration applies to all configurations of the subject technology.
- a disclosure relating to a configuration may apply to all configurations, or one or more configurations.
- a configuration may provide one or more examples.
- a phrase such as a “configuration” may refer to one or more configurations and vice versa.
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Otolaryngology (AREA)
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Un dispositif respiratoire comprend un cadre creux ayant une section pont et deux éléments de support. La section pont comprend une partie proximale conçue pour reposer sur un philtrum du patient lorsque les deux éléments de support du cadre sont placés sur chaque oreille respective du patient, et une partie distale s'étendant dans une direction latérale à l'opposé de la partie proximale. Un raccord d'alimentation en gaz fournit un gaz à travers un intérieur du cadre creux à au moins un orifice de sortie situé dans la section pont. Le dispositif respiratoire comprend une unité de commande couplée au cadre, et un substrat à film mince fournissant des capacités de communication électrique est positionné à l'intérieur du cadre, entre l'unité de commande et la section pont, de multiples appendices passant à travers une paroi de la section pont pour fournir un capteur à l'extérieur de la section pont.
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US202163286487P | 2021-12-06 | 2021-12-06 | |
US63/286,487 | 2021-12-06 |
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US5069222A (en) * | 1990-08-31 | 1991-12-03 | Mcdonald Jr Lewis D | Respiration sensor set |
US6165133A (en) * | 1995-11-17 | 2000-12-26 | New York University | Apparatus and method for monitoring breathing patterns |
US20020124849A1 (en) * | 2000-05-26 | 2002-09-12 | Taema | Nasal breathing mask with adjustable thermistor for treating respiratory disorders of sleep |
WO2011079262A2 (fr) * | 2009-12-24 | 2011-06-30 | Salter Labs | Canule et capteur de température de courant d'air combinés et leur procédé d'utilisation |
US20120203127A1 (en) * | 2011-02-07 | 2012-08-09 | Slp Ltd. | Nasal cannula with integrated thermal flow sensing |
WO2020252067A1 (fr) * | 2019-06-11 | 2020-12-17 | Vyaire Medical, Inc. | Dispositif de fixation de capteur de respiration |
WO2021058290A1 (fr) * | 2019-09-27 | 2021-04-01 | Koninklijke Philips N.V. | Interface patient avec oxymètre |
WO2022221316A1 (fr) * | 2021-04-13 | 2022-10-20 | Vyaire Medical, Inc. | Canule d'oxygénation avec circuit de mesure flexible |
-
2022
- 2022-12-05 WO PCT/US2022/051864 patent/WO2023107401A1/fr unknown
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
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US5069222A (en) * | 1990-08-31 | 1991-12-03 | Mcdonald Jr Lewis D | Respiration sensor set |
US6165133A (en) * | 1995-11-17 | 2000-12-26 | New York University | Apparatus and method for monitoring breathing patterns |
US20020124849A1 (en) * | 2000-05-26 | 2002-09-12 | Taema | Nasal breathing mask with adjustable thermistor for treating respiratory disorders of sleep |
WO2011079262A2 (fr) * | 2009-12-24 | 2011-06-30 | Salter Labs | Canule et capteur de température de courant d'air combinés et leur procédé d'utilisation |
US20120203127A1 (en) * | 2011-02-07 | 2012-08-09 | Slp Ltd. | Nasal cannula with integrated thermal flow sensing |
WO2020252067A1 (fr) * | 2019-06-11 | 2020-12-17 | Vyaire Medical, Inc. | Dispositif de fixation de capteur de respiration |
WO2021058290A1 (fr) * | 2019-09-27 | 2021-04-01 | Koninklijke Philips N.V. | Interface patient avec oxymètre |
WO2022221316A1 (fr) * | 2021-04-13 | 2022-10-20 | Vyaire Medical, Inc. | Canule d'oxygénation avec circuit de mesure flexible |
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