WO2023078479A1 - Complément alimentaire - Google Patents

Complément alimentaire Download PDF

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Publication number
WO2023078479A1
WO2023078479A1 PCT/CZ2022/000043 CZ2022000043W WO2023078479A1 WO 2023078479 A1 WO2023078479 A1 WO 2023078479A1 CZ 2022000043 W CZ2022000043 W CZ 2022000043W WO 2023078479 A1 WO2023078479 A1 WO 2023078479A1
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WO
WIPO (PCT)
Prior art keywords
composition
added
ginger
food supplement
food
Prior art date
Application number
PCT/CZ2022/000043
Other languages
English (en)
Inventor
Serhiy Sovyak
Original Assignee
Serhiy Sovyak
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serhiy Sovyak filed Critical Serhiy Sovyak
Priority to EP22809325.8A priority Critical patent/EP4426135A1/fr
Publication of WO2023078479A1 publication Critical patent/WO2023078479A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/212—Starch; Modified starch; Starch derivatives, e.g. esters or ethers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures

Definitions

  • iodine-containing medical products that are either used as a safe external disinfection agent for the human body (Lugol’s solution, lodiuoh Iodoform, povidone-iodines), or that can be used for ingestion, or in compositions (i.m., i.v. application) to treat thyroid gland diseases (potassium iodide, iodine, Renessans etc.).
  • the object of the present invention is a food supplement comprising a composition of a saponin and an amyloid substance, free iodine ions being bound to the obtained composition to produce a sesquiterpenoid-iodide, which improves immunity and practically reduces the toxic influence of free iodine ions to a minimum.
  • the principle of the food supplement according to the invention is that the composition comprises from 14.5 to 15.5 g of an amyloid substance, the amyloid substance being food-grade starch, 10.0 to 12,0 g of a saponin, the used saponin being fresh ginger, and 19.6 to 20.0 g of a 5% solution of iodine in ethanol.
  • the sesquiterpenes comprised in the ginger extract increase their efficiency (synergic effect).
  • Other excipients are food-grade glucose in the amount of 25.0 to 35.0 g and sugar in a quantity of 75.0 to 110.0 g.
  • the sugar and glucose mixture may be replaced with fructose in a quantity of 90.0 to 110.0 g. So far. prior-art products have proved that they carry antimicrobial, antiviral and antibacterial effects that were used to treat cholera, dysentery, chlamydia as well as to treat tonsillitis and other diseases with severe symptoms.
  • the present invention provides a complex compound with an absolutely precise iodine dose where iodine is in. a biologically active and non-toxic form.
  • iodine is used in the J + valency unlike e.g. the use of Lugol's solution, which comprises iodine (I 2 ) and potassium iodide (KI) dissolved in distilled water. Potassium iodide makes dissolution of iodine in water possible, producing I 3 - ions.
  • the solution is also an oxidation antiseptic agent, but is inconvenient in that it may cause scars or temporary discoloration of skin. It is not intended for digestion, because iodine in the solution is in the valency and comprises toxic elementary iodine.
  • the inventive food supplement comprises compounds of polysaccharides and iodine.
  • iodine is present in the J + valency, which is a safer and more considerate iodine complex intended for internal use.
  • Blue-coloured iodine in the J + valency is the basic trace element for living organisms. It is this form of iodine that can be found and accumulated in tissues and organs of higher animals and humans.
  • Compounds of iodine in the J + valency starch complex of iodine
  • the novelty of the present invention consists in the combination of saponins with amyloid structures that have the ability to bind free iodine ions, producing sesquiterpenoid-iodides that improve the support of immunity and also reduce the toxic influence of free iodine ions to a minimum. For this reason, we are submitting an invention relating to a new food supplement that is very efficient and influences immunity as an antibacterial, antiviral product for the human body.
  • Fresh ginger which comprises saponins, has positive effects on the alimentary tract proved by many clinical studies. Its active constituents positively stimulate digestion and absorption. Brown rat experiments have confirmed that flesh ginger influences hypoglycaemia, hypocholesterolemia (low cholesterol content in blood) and hypolipidemia and that it might also be used to treat diabetic complications.
  • sugar refers to the disaccharide sucrose consisting of D-glucose and D-fructose.
  • D-glucose is that it is necessary for the function of the human body; it is the essential and fastest energy source for all body tissues.
  • glucose is the only source of energy, which they cannot do without. These tissues consume about 150 g of glucose during 24 hours. Besides, glucose serves as a detoxicant during serious illnesses.
  • Lemons contain a high quantity of ascorbic acid and citric acid (3.5-8.0 g/100 g), they have approximately 87 % of water. Therefore, they are used in the natural form in a number of foods; it is especially their juice that is used. They further comprise bioflavonoids, pectin, aromatic essences, provitamin A, vitamin B, about 3 % of saccharides. It is also a source of calcium, potassium, phosphorus, magnesium, iron, zinc and others.
  • lemon juice is also advantageous within the present invention for pH adjustment of the entire composition.
  • the production method of the food supplement consists in a fresh sliced/diced ginger rhizome being subjected to extraction for 10-15 minutes in 4/5 parts of boiling water of the total volume of water designed for the production, the obtained extract, being separated by decanting, filtering. Subsequently, a mixture with 1/5 parts of the total water volume (t° ⁇ 40 °C) of starch, sugar and glucose or only starch, blended into a homogeneous condition, is added to the boiling ginger extract. The boiled mixture is left to stand for a certain time (at least 20 minutes) to let. the starch gelatinize. Lemon juice is added to the swollen suspension under stirring, and then a iodine solution in ethanol, in the temperature range of approx. 30 - 80 °C.
  • fructose In the case of producing a product with fructose, suitable e.g. for diabetics, sugar and glucose are not used. Fructose is only added to the final food supplement at the end of the production.
  • the novelty of the production method consists in the lemon juice and Iodine solution in ethanol being added to the above-mentioned composition at an elevated temperature (at 30 - 80 °C). Since normally, a iodine solution in ethanol is added at. the room temperature.
  • Example 1 A production method of a food supplement in the gel solution form, comprising: starch - 15.0 g
  • the food supplement was produced in the following way: 10.0 g of fresh sliced/diced ginger is extracted in 720.0 g of boiling water and the obtained extract is separated by decanting, filtering.
  • the boiled mixture is left to stand for at least 20 min to let the starch gelatinize.
  • 30.0 g of natural lemon juice is added to the swollen suspension at 30 - 80 °C, and then 19.8 g of a 5% iodine solution in ethanol at 30 - 80 °C.
  • the final product is in the form of a gel solution.
  • Example 2 A production method of a food supplement in the gel solution form, comprising:
  • the boiled mixture is left to stand for at least. 20 min to let the starch gelatinize.
  • 25.0 g of natural lemon juice is added to the swollen suspension at 30 - 80 °C, and then 20.0 g of a 5% iodine solution in ethanol at 30 ⁇ 80 °C.
  • the final product is in the form of a gel solution.
  • Example 3 A production method of a food supplement In the gel solution form, comprising: starch - 15.0 g 5% iodine solution in ethanol - 19.6 g fresh ginger - 10.0 g, and a mixture comprising natural lemon juice - 32.5 g sugar - 110.0 g glucose - 32.0 g and 950 g of potable water.
  • the following was used for the production of the food supplement: 10.0 g of fresh sliced/diced ginger, which is extracted in 760.0 g of boiling water, and the obtained extract is separated by decanting, filtering.
  • the boiled mixture is left to stand for at least 20 min to lei the starch gelatinize.
  • 32.5 g of natural lemon juice is added to the swollen suspension at 30 - 80 °C, and then 19.6 g of a 5% iodine solution in ethanol at 30 - 80 °C.
  • the final food supplement was produced in the form of a gel solution.
  • Example 4 A production method of a food supplement in the gel solution, form, comprising: starch - 14.5 g
  • the food supplement was produced in a similar way (see above), 12.0 g of fresh sliced/diced ginger, which is extracted in 720 g of boiling water, and the obtained extract is separated by decanting, filtering.
  • the boiled mixture is left to stand for at least 60 min to let the starch gelatinize. .35.0 g of natural lemon juice is added to the swollen suspension at 30 - 80 °C, and then 19.6 g of a 5% iodine solution in ethanol at 30 - 80 °C. Finally, 110.0 g of fructose is added at. a temperature lower than 60 °C. I'he final product is in the form of a gel solution.
  • a specialized facility subsequently proved the effect of all the analysed samples of the food supplement produced according to the Embodiment Examples 1 to 4 against the bacteria Escherichia coli, which may e.g. cause infection of the urinary tract or intestinal complications.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Un objet de la présente solution est un complément alimentaire pour renforcer l'immunité sous la forme d'une composition, la composition comprenant de 14,5 à 15,5 g d'amidon de qualité alimentaire, de 10,0 à 12,0 g de gingembre, de 19,6 à 20,0 g de solution d'iode à 5 % dans l'éthanol, de 25,0 à 35,0 g de jus de citron, de 850,0 à 950,0 g d'eau et en outre de 75,0 à 110,0 g de sucre, de 25,0 à 35,0 g de glucose ou de 90,0 à 110,0 g de fructose. Un objet de la présente solution est également un procédé de production du complément alimentaire.
PCT/CZ2022/000043 2021-11-02 2022-11-01 Complément alimentaire WO2023078479A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP22809325.8A EP4426135A1 (fr) 2021-11-02 2022-11-01 Complément alimentaire

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZPV2021-505 2021-11-02
CZ2021-505A CZ2021505A3 (cs) 2021-11-02 2021-11-02 Potravinový doplněk

Publications (1)

Publication Number Publication Date
WO2023078479A1 true WO2023078479A1 (fr) 2023-05-11

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Family Applications (1)

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PCT/CZ2022/000043 WO2023078479A1 (fr) 2021-11-02 2022-11-01 Complément alimentaire

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CZ (1) CZ2021505A3 (fr)
WO (1) WO2023078479A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020136802A1 (en) * 2000-09-29 2002-09-26 The Procter & Gamble Co. Beverage compositions comprising arabinogalactan and defined minerals
US20060024385A1 (en) * 2004-07-27 2006-02-02 Pedersen Mark A Metabolic capacity enhancing compositions and methods for use in a mammal
WO2016069580A1 (fr) * 2014-10-27 2016-05-06 VitaThinQ, Inc. Compléments nutritionnels
US20210220422A1 (en) * 2020-01-20 2021-07-22 Jonathan Parker Dietary supplement compositions and methods
US20210228483A1 (en) * 2018-06-11 2021-07-29 Seattle Gummy Company Low glycemic gummy composition and methods of making and using thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2189830C1 (ru) * 2001-05-21 2002-09-27 Общество с ограниченной ответственностью Фирма "ЭЙКОСЪ" Биологически активная добавка "лактогон"
US20210038664A1 (en) * 2018-02-09 2021-02-11 Atp Institute Pty Ltd Formulation and method of use
US11701335B2 (en) * 2018-08-31 2023-07-18 Apr Applied Pharma Research S.A. Methods of normalizing amino acid metabolism

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020136802A1 (en) * 2000-09-29 2002-09-26 The Procter & Gamble Co. Beverage compositions comprising arabinogalactan and defined minerals
US20060024385A1 (en) * 2004-07-27 2006-02-02 Pedersen Mark A Metabolic capacity enhancing compositions and methods for use in a mammal
WO2016069580A1 (fr) * 2014-10-27 2016-05-06 VitaThinQ, Inc. Compléments nutritionnels
US20210228483A1 (en) * 2018-06-11 2021-07-29 Seattle Gummy Company Low glycemic gummy composition and methods of making and using thereof
US20210220422A1 (en) * 2020-01-20 2021-07-22 Jonathan Parker Dietary supplement compositions and methods

Also Published As

Publication number Publication date
CZ309544B6 (cs) 2023-03-29
CZ2021505A3 (cs) 2023-03-29

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