WO2023072193A1 - State control apparatus and method, and electrical stimulus device and medical instrument - Google Patents

Abstract

The present application relates to a state control apparatus and method, and an electrical stimulus device and a medical instrument. The state control apparatus is configured to: in response to a treatment instruction, generate a periodic control pulse signal, the control pulse signal comprising a parameter control pulse signal, a treatment control pulse signal and a low-power-consumption control pulse signal; and according to the parameter control pulse signal, the treatment control pulse signal and the low-power-consumption control pulse signal, control an electrical stimulus assembly to output a periodic preset treatment signal, with the period of the preset treatment signal being equal to the period of the parameter control pulse signal, and the preset treatment signal comprising a preset low-power-consumption waveform, and a stimulus pulse having the same pulse width as that of the parameter control pulse signal.

Description

State control device, method, electrical stimulation device and medical device

related application

This application claims the priority of the Chinese patent application filed on October 28, 2021, with the application number 202111261522.3, entitled "State Control Device, Method, Electrical Stimulation Equipment, and Medical Device", which is hereby incorporated by reference in its entirety.

technical field

The application belongs to the technical field of electronic equipment, and specifically relates to a state control device, method, electrical stimulation equipment and medical equipment.

Background technique

With the development of brain surgery technology and neuroelectronic science and technology, as well as the increasing types and incidence of middle-aged and elderly cranial nerve diseases, some electrical stimulation medical devices are used in the neurointerventional surgery for the treatment of brain tissue, and Played a good clinical effect.

Contents of the invention

The first aspect of the present application provides a state control device for controlling the state of an output signal of an electrical stimulation component of an electrical stimulation device, the state control device includes a controller connected to the electrical stimulation component, and the controller is controlled by Configured as:

Generate periodic control pulse signals in response to treatment instructions, the control pulse signals include parameter control pulse signals, treatment control pulse signals and low power consumption control pulse signals;

According to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal, the electrical stimulation component is controlled to output a periodic preset treatment signal; the period of the preset treatment signal is equal to that of the parameter control pulse signal Period, the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal.

In one of the embodiments, the triggering moment of the treatment control pulse signal corresponds to the rising edge, and the triggering moment of the low power consumption control pulse signal is the same as the triggering moment of the treatment control pulse signal and ahead of the parameter control pulse The rising edge of the signal, the triggering moment of the low power consumption control pulse signal corresponds to the falling edge; the generation of a periodic control pulse signal in response to the treatment instruction includes: starting from the triggering moment of the treatment control pulse signal Timing/counting at all times, and controlling the treatment control pulse signal to maintain a high level and controlling the low power consumption control pulse signal to maintain a low level; triggering the first rising edge of the parameter control pulse signal at the first preset time ;Trigger the first falling edge of the parameter control pulse signal and the first falling edge of the treatment control pulse signal at the second preset moment; trigger the first falling edge of the low power consumption control pulse signal at the third preset moment Rising edge; trigger the second rising edge of the parameter control pulse signal at the fourth preset moment; wherein, the time difference between the fourth preset moment and the first preset moment is equal to the parameter control pulse signal cycle.

In one of the embodiments, the preset treatment signal also includes a stimulation intermittent waveform; the electrical stimulation component is controlled to output periodic pulse signals according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal The preset treatment signal includes: triggering the first rising edge of the preset treatment signal at the first preset moment; triggering the first falling edge of the preset treatment signal at the second preset moment; the stimulation intermittent waveform; at the third preset moment, stop the stimulation intermittent waveform and trigger the preset low power consumption waveform; stop the preset low power consumption waveform at the fourth preset moment and trigger the preset low power consumption waveform The second rising edge of the preset therapy signal.

In one embodiment, the stimulation intermittent waveform is low level, and the maximum value of the preset low power consumption waveform is less than or equal to the minimum value of the low level.

In one of the embodiments, the controller is further configured to: acquire the frequency of the internal clock of the controller, and generate the control pulse signal according to the frequency of the clock in response to the treatment instruction; or acquire the frequency of the clock The controller internally presets the timing of the delay function, and generates the control pulse signal according to the timing of the preset delay function.

In one of the embodiments, the state control device further includes an oscillator connected to the controller for triggering the controller to generate the control pulse signal.

In one of the embodiments, the controller is further configured to: obtain the cycle of the wake-up interrupt signal provided by the oscillator to the controller; respond to the treatment instruction, generate The control pulse signal.

In one embodiment, the treatment instruction includes a preset parameter for setting at least one of the period, pulse width and duration of the preset low power waveform of the preset treatment signal.

In one of the embodiments, the controller is further configured to: obtain the treatment instruction from the terminal device, and generate a control pulse signal containing the preset parameters according to the treatment instruction.

The second aspect of the present application provides an electrical stimulation device, including an electrical stimulation component, and any state control device described in the embodiments of the present application.

In one of the embodiments, the electrical stimulation device further includes a communication module connected to the controller; wherein, the controller obtains the treatment instruction and the /or configuration parameters, the configuration parameters include at least one of the period, pulse width and duration of the preset low power consumption waveform of the preset treatment signal.

In one of the embodiments, the communication module includes a Bluetooth module, which is connected to the controller; wherein, the controller acquires the treatment instruction and/or the configuration parameters through the Bluetooth module.

In one embodiment, the electrical stimulation component includes several electrodes connected to the controller.

In one of the embodiments, the electrical stimulation device is an implantable electrical stimulation device.

A third aspect of the present application provides a medical device, including any electrical stimulation device described in the embodiments of the present application.

The fourth aspect of the present application provides a state control method, which is applied to the state control device described in any embodiment of the present application; the method includes: generating a periodic control pulse signal in response to a treatment instruction, and the control The pulse signal includes a parameter control pulse signal, a treatment control pulse signal and a low power consumption control pulse signal; according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal, the electrical stimulation component is controlled to output a periodic preset Set a treatment signal; the period of the preset treatment signal is equal to the period of the parameter control pulse signal, and the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal .

A fifth aspect of the present application provides a state control circuit for controlling the state of an output signal of an electric stimulation component of an electric stimulation device, the state control circuit comprising a control pulse signal generation module and a preset treatment signal generation module. The control pulse signal generation module includes a control unit, the control unit is configured to generate a periodic control pulse signal in response to a treatment instruction, and the control pulse signal includes a parameter control pulse signal, a treatment control pulse signal and a low power consumption control pulse signal. Pulse signal. The preset treatment signal generation module is configured to control the electrical stimulation component to output a periodic preset treatment signal according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal; the preset treatment The period of the signal is equal to the period of the parameter control pulse signal, and the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal.

The details of various embodiments of the invention are set forth in the accompanying drawings and the description below. From the description, drawings and claims, those skilled in the art will easily understand other features, problems to be solved and beneficial effects of the present invention.

Description of drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings that need to be used in the description of the embodiments. Obviously, the drawings in the following description are only some embodiments of the present application. Those of ordinary skill in the art can also obtain the drawings of other embodiments according to these drawings without any creative effort.

FIG. 1 is a schematic structural diagram of a state control device provided in an embodiment of the present application;

Fig. 2 is a schematic flow chart of the execution steps of the controller of the state control device in Fig. 1;

Fig. 3 is a schematic diagram of a working waveform of a state control device provided in an embodiment of the present application and a schematic diagram of a waveform of a corresponding preset treatment signal;

FIG. 4 is a schematic waveform diagram of a state control device controlling an electrical stimulation component to output a preset treatment signal provided in an embodiment of the present application;

Fig. 5 is a schematic flow chart of steps executed by a controller of a state control device provided in an embodiment of the present application;

FIG. 6 is a schematic structural diagram of a state control device provided in another embodiment of the present application;

Fig. 7 is a schematic structural diagram of an electrical stimulation device provided in an embodiment of the present application;

Fig. 8 is a schematic structural diagram of an electrical stimulation device provided in another embodiment of the present application;

Fig. 9 is a schematic workflow diagram of a medical device provided in an embodiment of the present application;

FIG. 10 is a functional block diagram of a state control circuit provided in an embodiment of the present application;

FIG. 11 is another functional block diagram of a state control circuit provided in an embodiment of the present application;

FIG. 12 is a schematic structural diagram of a state control circuit provided in an embodiment of the present application.

Detailed ways

In order to facilitate the understanding of the present application, the present application will be described more fully below with reference to the relevant drawings. Preferred embodiments of the application are shown in the accompanying drawings. However, the present application can be embodied in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the understanding of the disclosure of the application more thorough and comprehensive.

Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the technical field to which this application belongs. The terms used herein in the specification of the application are only for the purpose of describing specific embodiments, and are not intended to limit the application. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

In the case of using "comprising", "having", and "comprising" described herein, another element may also be added unless an explicit qualifying term such as "only", "consisting of" etc. is used . Unless mentioned to the contrary, the terms of a singular form may include a plural form and shall not be construed as one in number.

It should be understood that although the terms "first", "second", etc. may be used herein to describe various elements, these elements should not be limited by these terms. These terms are only used to distinguish one element from another. For example, a first element could be termed a second element, and, similarly, a second element could be termed a first element, without departing from the scope of the application.

In this application, unless otherwise clearly specified and limited, terms such as "connected" and "connected" should be interpreted in a broad sense, for example, they can be directly connected or indirectly connected through an intermediary, and they can be internally connected to each other. connectivity or interaction between two elements. Those of ordinary skill in the art can understand the specific meanings of the above terms in this application according to specific situations.

The applicant found that traditional implantable electrical stimulation medical devices have high power consumption and require frequent charging, resulting in frequent charging of the battery, affecting battery life, and increasing the risk and speed of battery damage.

Therefore, how to increase the working time of the implanted electrical stimulation medical device after charging has become one of the technical problems that need to be solved urgently for such devices.

Based on this, it is necessary to address the above technical problems and provide a state control device, method, electrical stimulation equipment and medical equipment, which can reduce the energy consumption of the product during the working cycle without increasing the volume of the product, thereby improving the battery life of the product after charging. operating hours.

Please refer to FIG. 1-FIG. 2. In one embodiment of the present application, a state control device 100 is provided for controlling the state of the output signal of the electrical stimulation component 20 of the electrical stimulation device 200. The state control device 100 includes an electric The stimulus component 20 is connected to the controller 10, and the controller 10 is configured to perform the following steps:

Step S110: Generate a periodic control pulse signal in response to the treatment instruction, the control pulse signal includes a parameter control pulse signal, a treatment control pulse signal and a low power consumption control pulse signal;

Step S120: According to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal, control the electrical stimulation component to output a periodic preset treatment signal; the period of the preset treatment signal is equal to the parameter control The period of the pulse signal, the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal.

Please continue to refer to FIGS. 1-2 , by configuring the controller 10 to generate periodic control pulse signals in response to treatment instructions, the control pulse signals include parameter control pulse signals, treatment control pulse signals and low power consumption control pulse signals; The controller 10 can control the electrical stimulation component 20 to output a periodic preset treatment signal according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal; the period of the preset treatment signal is equal to the parameter control The period of the pulse signal, the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal, so that the product periodically outputs the treatment signal to ensure the treatment effect while reducing the product Energy consumption per unit time. This application does not add additional electronic components or batteries, only by controlling the state of the output signal of the electrical stimulation component 20 of the electrical stimulation device 200, the energy consumption per unit time of the product is reduced, the working time of the product after charging is improved, and the implementation cost is low. , the control effect is good.

As an example, please refer to Figure 3-Figure 4, the trigger time of the treatment control pulse signal S1 can be set to correspond to the rising edge, and the trigger time of the low power consumption control pulse signal S2 is set to be the same as the trigger time of the treatment control pulse signal S1, both are t0 , and ahead of the rising edge of the parameter control pulse signal S0, the trigger time of the low power consumption control pulse signal S2 is set to correspond to the falling edge; the generation of periodic control pulse signals in response to the treatment instructions includes: self-treatment control pulse signals The trigger time of S1 is timing/counting at the start time, and the treatment control pulse signal S1 is controlled to maintain a high level and the low power consumption control pulse signal S2 is controlled to maintain a low level; the parameter control pulse signal S0 is triggered at the first preset time t1 trigger the first falling edge of the parameter control pulse signal S0 and the first falling edge of the treatment control pulse signal S1 at the second preset time t2; trigger the low power consumption control pulse signal at the third preset time t3 The first rising edge of S2; the second rising edge of the parameter control pulse signal S0 is triggered at the fourth preset moment t4; wherein, the time difference between the fourth preset moment t4 and the first preset moment t1 is equal to the parameter control pulse signal S0 The cycle T.

Further, please continue to refer to FIG. 3-FIG. 4, the preset treatment signal D0 also includes a stimulation intermittent waveform (such as the waveform between the second preset time t2 and the third preset time t3); the control according to the parameters The pulse signal, the treatment control pulse signal and the low power consumption control pulse signal control the electrical stimulation component to output a periodic preset treatment signal, including: triggering the first rising edge of the preset treatment signal D0 at the first preset time t1; Trigger the first falling edge of the preset treatment signal D0 and stimulate the intermittent waveform at the second preset moment t2; stop stimulating the intermittent waveform at the third preset moment t3 and trigger the preset low power consumption waveform (for example, the third preset moment t3 and the fourth preset time t4); at the fourth preset time t4, the preset low power consumption waveform is stopped and the second rising edge of the preset treatment signal D0 is triggered. It can be understood that the time difference between the fourth preset moment t4 and the first preset moment t1 is also equal to the period of the preset treatment signal D0. That is to say, starting from the fourth preset time t4, the controller controls the electric stimulation component to output the second periodic preset treatment signal according to the parameter control pulse signal, the treatment control pulse signal and the low power consumption control pulse signal, so as to analogy. As an example, please continue to refer to Figures 3-4, you can set the stimulation intermittent waveform (the waveform between the second preset time t2 and the third preset time t3) to a low level, and set the preset low power consumption waveform (the first The maximum value of the waveform between the third preset time t3 and the fourth preset time t4 is less than or equal to the minimum value of the stimulation intermittent waveform. Make the product periodically output the treatment signal with the preset period T as the period value, so as to ensure the treatment effect and reduce the energy consumption of the product per unit time.

As an example, please continue to refer to Figure 4, the amplitude of the stimulation pulse between the first preset moment t1 and the second preset moment t2 can be set to 0V-10.0V, the second preset moment t2 and the third preset moment The amplitude of the stimulation intermittent waveform between t3 is 0V-3.0V; the difference between the first preset moment t1 and the second preset moment t2 can be set to 20μs-450μs, for example, the first preset moment can be set The difference between t1 and the second preset time t2 is 20 μs, 80 μs, 100 μs, 140 μs, 200 μs, 290 μs, 330 μs, 390 μs or 450 μs. The difference T between the fourth preset moment t4 and the first preset moment t1 can be set as 4.0ms-500.0ms, for example, the difference between the fourth preset moment t4 and the first preset moment t1 can be set T is 4.0ms, 100.2ms, 200.5ms, 300.8ms, 400.8ms or 500.0ms. Electrical stimulation equipment generally consumes a lot of energy during the period of outputting stimulation pulses between the first preset time t1 and the second preset time t2, and outputs stimulation intermittent waveforms between the second preset time t2 and the third preset time t3 The energy consumption during the period is small, and the energy consumption during the period of outputting the preset low power consumption waveform between the third preset time t3 and the fourth preset time t4 is within the preset energy consumption range. Since the sources of energy consumption between the third preset time t3 and the fourth preset time t4 mainly include timers or counters, the energy consumption is very small. The proportion of time for outputting stimulation pulses in the period T of the preset treatment signal is very small, so that the energy consumption per unit time of the product is very small, and the working time of the product after charging is effectively improved. The preset times disclosed in this application include four, respectively t1, t1, t3 and t4, but are not limited to four preset times. During specific implementation, more than three preset times can be set according to the actual situation, for example Five, six, etc. preset moments.

As an example, continuing to refer to Figure 5, the controller can be configured to perform the following steps:

Step S111: Obtain the frequency of the internal clock of the controller, and generate the control pulse signal according to the frequency of the clock in response to the treatment instruction; or obtain the time set by the internal preset delay function of the controller, generating the control pulse signal according to the timing timed by the preset delay function;

Step S120: According to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal, control the electrical stimulation component to output a periodic preset treatment signal; the period of the preset treatment signal is equal to the parameter control The period of the pulse signal, the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal.

As an example, please continue to refer to Figure 5, you can turn off the watchdog, set the frequency of the internal clock of the controller, for example, 1MHZ, set the IO port of the controller to output mode and select the IO port as the output port, and use the internal clock of the controller In the low power consumption mode, a parameter control pulse signal, a treatment control pulse signal and a low power consumption control pulse signal are generated according to the treatment instruction, wherein the period of the parameter control pulse signal is equal to the duty cycle of the internal clock, and the operation of the internal clock The period can be calculated and obtained according to the frequency of the internal clock, so that the controller can control the electrical stimulation component to output a periodic preset treatment signal according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal; The period of the preset treatment signal is equal to the period of the parameter control pulse signal, and the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal, thereby effectively Reduce product energy consumption.

As an example, please continue to refer to Figure 5, the controller can be set to control the electrical stimulation component to stop according to the preset delay function from the start moment of controlling the electrical stimulation component to output the stimulation pulse in the treatment mode. After the stimulation pulse, the preset low power consumption waveform is output, so that the controller can control the electrical stimulation component to output a periodic preset treatment signal according to the parameter control pulse signal, the treatment control pulse signal and the low power consumption control pulse signal The period of the preset treatment signal is equal to the period of the parameter control pulse signal, and the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal.

As an example, referring to FIG. 6 , it can be set that the state control device 100 further includes an oscillator 30 connected to the controller 10 for triggering the controller 10 to generate a control pulse signal.

As an example, please continue to refer to FIG. 6, the parameter control pulse signal can be set to include a wake-up interrupt signal; the oscillator 30 can be used to provide the wake-up interrupt signal to the controller 10; the controller 10 is also configured to: obtain the wake-up interrupt signal period; in response to the treatment instruction, generate the control pulse signal according to the period of the wake-up interrupt signal, the control pulse signal includes a parameter control pulse signal, a treatment control pulse signal and a low power consumption control pulse signal, wherein, The period of the parameter control pulse signal is equal to the period of the wake-up interrupt signal. The electrical stimulation device 200 generates periodic control pulse signals according to the treatment instructions, and the control pulse signals include parameter control pulse signals, treatment control pulse signals and low power consumption control pulse signals, thereby effectively reducing product energy consumption.

Please refer to FIG. 7 , in one embodiment of the present application, an electrical stimulation device 200 is provided, including the electrical stimulation component 20 and the state control device 100 in any embodiment of the present application.

As an example, please refer to FIG. 8 , it can be set that the electrical stimulation device 200 also includes a communication module 40, and the communication module 40 is connected to the controller 10; /or configure parameters, and generate a control pulse signal containing the preset parameters according to the treatment instruction, the treatment instruction can be set to include the period, pulse width and duration of the preset low-power waveform for setting the preset treatment signal At least one of the preset parameters, so that before the user sends the treatment instruction on the terminal device 201, setting the treatment instruction includes at least One kind of preset parameters, the electrical stimulation device 200 obtains the preset parameters contained in the treatment instructions during the process of receiving the treatment instructions, and the electrical stimulation device 200 generates periodic control pulse signals according to the treatment instructions, and the control pulse signals include Parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal; wherein, the period of the parameter control pulse signal is equal to the period in the preset parameters, and the pulse width of the parameter control pulse signal is equal to the period in the preset parameters pulse width. The user may also be prompted to set configuration parameters before the user sends a treatment instruction on the terminal device 201, and at least one of the cycle, pulse width, and duration of the preset low-power waveform is set by the user on the terminal device 201. After that, the user is prompted whether to confirm sending the treatment instruction, and after the user clicks the confirmation button, the treatment instruction is sent, so that the electrical stimulation device 200 generates a periodic control pulse signal according to the treatment instruction, and the control pulse signal includes a parameter control pulse signal . Treatment control pulse signal and low power consumption control pulse signal; wherein, the period of the parameter control pulse signal is equal to the period in the configuration parameters, and the pulse width of the parameter control pulse signal is equal to the pulse width in the configuration parameters.

As an example, please continue to refer to FIG. 8 , the communication module 40 can be set to include a Bluetooth module 41 , and the Bluetooth module 41 is connected to the controller 10 ; wherein, the controller 10 obtains treatment instructions and/or configuration parameters through the Bluetooth module 41 . For example, the user can set preset parameters included in the treatment instruction via the terminal device 201 , or send configuration parameters to the electrical stimulation device 200 via the terminal device 201 before sending the treatment instruction. In an embodiment of the present application, the terminal device 201 may include at least one of a desktop computer, an all-in-one computer, a tablet computer, a mobile phone, an industrial computer, a smart watch, or a smart wearable device.

As an example, please continue to refer to FIG. 8 , the electrical stimulation component 20 may be configured to include several electrodes 21 connected to the controller 10 , so as to provide a treatment signal of a preset period to the target area to be treated via the electrodes 21 . For example, electro-stimulation device 200 is an implantable electro-stimulation device. The controller 10 generates a periodic control pulse signal in response to the treatment instruction, and the control pulse signal includes a parameter control pulse signal, a treatment control pulse signal and a low power consumption control pulse signal; so that the controller 10 can control the pulse signal according to the parameters , the treatment control pulse signal and the low power consumption control pulse signal control the electrical stimulation component 20 to output a periodic preset treatment signal; the period of the preset treatment signal is equal to the period of the parameter control pulse signal, and the preset treatment signal Including the preset low power consumption waveform and the stimulation pulse with the same pulse width as the parameter control pulse signal enables the product to periodically output the treatment signal to ensure the treatment effect while reducing the energy consumption of the product per unit time. This application does not add additional electronic components or batteries, and only controls the state of the output signal of the electrode 21 through the controller itself, which reduces the energy consumption per unit time of the product and improves the working time of the product after charging, thus effectively reducing the patient's anxiety. The frequency and times of charging required for implantable medical devices improve the comfort of use.

As an example, please refer to FIG. 9 , in one embodiment of the present application, a medical device is provided, including any electrical stimulation device in any embodiment of the present application. You can turn off the watchdog, set the frequency of the internal clock of the controller, such as 1MHZ, set the IO port of the controller to output mode and select the IO port as the output port, and the controller obtains the frequency of its internal clock or a preset delay function Timing time; this embodiment enables the electrical stimulation component to output preset treatment signals and effectively reduce energy consumption of the product. The controller can be set to enter the charging state when near-field communication is detected; when the controller is set to detect Bluetooth communication, the controller communicates with the connected terminal device via the Bluetooth module, and the controller can obtain information from the terminal device treatment instructions and/or configuration parameters; and set the controller to collect equipment data when it detects that the data collection conditions are met, so as to analyze the operation of the equipment based on the equipment data and remotely analyze whether there is a fault and the cause of the fault. For example, the user can set the preset parameters contained in the treatment instruction via the terminal device, or send configuration parameters to the electrical stimulation device via the terminal device before sending the treatment instruction. At least one of the duration of the power consumption waveform and the like. If the controller detects that there is no near-field communication, no Bluetooth communication, and the data collection conditions are not met, the controller enters a low power consumption mode, and generates the control pulse signal according to the frequency of the clock; or self-controls the electronic From the start moment when the stimulation component outputs the stimulation pulse, the electrical stimulation component is regularly controlled according to the preset delay function to output the preset low-power waveform after the stimulation pulse is suspended; so that the controller The control pulse signal, the treatment control pulse signal and the low power consumption control pulse signal control the electrical stimulation component to output a periodic preset treatment signal; the period of the preset treatment signal is equal to the period of the parameter control pulse signal, and the The preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal. Wherein, the period of the parameter control pulse signal is equal to the duty cycle of the internal clock, and the duty cycle of the internal clock can be calculated and obtained according to the frequency of the internal clock, so that the controller can control the pulse signal and the treatment control pulse according to the parameters. The signal and the low power consumption control pulse signal control the electrical stimulation component to output a periodic preset treatment signal, thereby effectively reducing energy consumption of the product.

As an example, in one embodiment of the present application, a state control method is provided, which is applied to the state control device in any embodiment of the present application; the method includes: generating periodic control pulses in response to treatment instructions signal, the control pulse signal includes a parameter control pulse signal, a treatment control pulse signal and a low power consumption control pulse signal; the electric stimulation component is controlled according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal Output a periodic preset treatment signal; the period of the preset treatment signal is equal to the period of the parameter control pulse signal, and the preset treatment signal includes a preset low power consumption waveform and a pulse with the parameter control pulse signal Stimulus pulses of the same width.

As an example, in one embodiment of the present application, referring to FIG. 10 , a state control circuit 101 is provided for controlling the state of the output signal of the electrical stimulation component 20 of the electrical stimulation device. The state control circuit 101 includes a control pulse signal A generation module 1011 and a preset treatment signal generation module 1012 . The control pulse signal generation module 1011 includes a control unit 1013 configured to generate periodic control pulse signals in response to treatment instructions, and the control pulse signals include parameter control pulse signals, treatment control pulse signals and low power consumption control pulse signals. The preset treatment signal generation module 1012 is configured to control the electrical stimulation component to output a periodic preset treatment signal according to the parameter control pulse signal, the treatment control pulse signal and the low power consumption control pulse signal; the period of the preset treatment signal is equal to the parameter control pulse The period of the signal, the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal.

Referring to FIG. 11 , in an example, the preset treatment signal generating module 1012 includes a first enabling unit 1111 , a second enabling unit 1112 and a third enabling unit 1113 . One end of the first enabling unit 1111, the second enabling unit 1112, and the third enabling unit 1113 are respectively connected to the control unit 1013, and the other ends are respectively connected to the electrical stimulation component 20 for controlling pulses according to parameters respectively The signal, the treatment control pulse signal and the low power consumption control pulse signal control the electrical stimulation component 20 to output periodic preset treatment signals.

In one example, referring to FIG. 12 , an implementation of a state control circuit is provided. The first enabling unit 1111 includes a first switch K0, an operational amplifier 1202, a MOS transistor 1204 and a current sampling resistor R. The first end of the first switch K0 is connected to the control unit 1013 and is configured to receive a parameter control pulse signal as an enabling signal. The second terminal of the first switch K0 is connected to the first input terminal/inverting input terminal of the operational amplifier 1202, and the first input terminal of the operational amplifier 1202 is connected to the output terminal of the digital-to-analog converter DAC through the third terminal of the first switch K0 , and its second input terminal/non-inverting input terminal is connected to the current sampling resistor R, and the output terminal of the operational amplifier 1202 is connected to the first terminal of the electrical stimulation component 20 through the drain-source terminal of the MOS transistor 1204 and the first capacitor C1. The operational amplifier 1202 compares the voltage between the first input terminal and the second input terminal, and then outputs the corresponding voltage to control the conduction resistance R of the MOS transistor 1204, thereby controlling the load current between the second capacitor C2 and the third capacitor C3 . The gate of the MOS transistor 1204 is grounded via the current sampling resistor R.

The second enabling unit 1112 includes a second switch K1 and a second capacitor C2 for energy storage; the first end of the second switch K1 is connected to the control unit 1013, configured to receive a treatment control pulse signal as an enabling signal; The second terminal of the second switch K1 is respectively connected to the second capacitor C2 and the third capacitor C3, and is connected to the second terminal of the electrical stimulation component 20 via the third capacitor C3. The second switch K1 also includes a third terminal that can be connected to a power supply VCC.

The third enabling unit 1113 includes a third switch K2, a DC blocking capacitor C3 and a first capacitor C1, the first end of the third switch K2 is connected to the control unit 1013, configured to receive a low power consumption control pulse signal as an enabling Signal. The third switch K2 is also connected across the two ends of the electrical stimulation component 20, and is respectively connected to the first terminal of the electrical stimulation component 20 via the first capacitor C1 and connected to the second terminal of the electrical stimulation component 20 via the third capacitor C3. The end of the third switch K2 connected to the second end of the electrical stimulation component 20 is also used to connect to the power supply VCC via the second switch K1.

The first enabling unit 1111, the second enabling unit 1112, and the third enabling unit 1113 described above are described as examples, and are not limited to this circuit. As those skilled in the art understand, any one of them can be replaced during specific implementation. are other circuits that can realize their respective functions.

As an example, please refer to Figure 3-Figure 4, you can set the trigger time of the treatment control pulse signal S1 to correspond to the rising edge, set the trigger time of the low power consumption control pulse signal S2 to be the same as the trigger time of the treatment control pulse signal S1, both are t0 , and ahead of the rising edge of the parameter control pulse signal S0, set the trigger time of the low power consumption control pulse signal S2 to correspond to the falling edge; the generation of a periodic control pulse signal in response to the treatment instruction includes: from the treatment control pulse signal The trigger time of S1 is timing/counting at the start time, and the treatment control pulse signal S1 is controlled to maintain a high level and the low power consumption control pulse signal S2 is controlled to maintain a low level; the parameter control pulse signal S0 is triggered at the first preset time t1 trigger the first falling edge of the parameter control pulse signal S0 and the first falling edge of the treatment control pulse signal S1 at the second preset time t2; trigger the low power consumption control pulse signal at the third preset time t3 The first rising edge of S2; the second rising edge of the parameter control pulse signal S0 is triggered at the fourth preset moment t4; wherein, the time difference between the fourth preset moment t4 and the first preset moment t1 is equal to the parameter control pulse signal S0 The cycle T.

It can be understood that the parameter control pulse signal S0, treatment control pulse signal S1 and low power consumption control pulse signal S2 can be output through the control unit 1013, and combined with the state control circuit provided by this embodiment in the electrical stimulation component 20 A periodic preset therapy signal is generated across the electrode contacts.

3, 4 and 12, at time t0, the second switch K1 of the state control circuit 101 is turned on in response to the high level of the treatment control pulse signal S1, and the power supply VCC makes the capacitor C2 Charge. At the first preset time t1, the first switch K0 is turned on in response to the high level of the parameter control pulse signal S0, by controlling the output voltage of the operational amplifier 1202, and then controlling the on-resistance of the drain-source terminal of the MOS transistor 1204, Thus, the first rising edge of the preset treatment signal D0 is triggered at the first preset time t1. Then, at the second preset time t2, the first switch K0 is turned off in response to the low level of the parameter control pulse signal S0, the second switch K1 is turned off in response to the low level of the treatment control pulse signal S1, and the electrical stimulation There is no current between the electrode contacts of the assembly 20, and the first falling edge of the preset treatment signal D0 and the intermittent stimulation waveform are triggered at the second preset time t2. At the third preset time t3, the third switch K2 is turned on in response to the high level of the low power consumption control pulse signal S2, generating a reverse current from C1 to C3, and stopping the intermittent stimulation waveform at the third preset time t3 And trigger a preset low power consumption waveform (for example, a waveform between the third preset time t3 and the fourth preset time t4). It can be understood that the time difference between the fourth preset moment t4 and the first preset moment t1 is also equal to the period of the preset treatment signal D0. That is to say, starting from the fourth preset time t4, the controller controls the electric stimulation component to output the second periodic preset treatment signal according to the parameter control pulse signal, the treatment control pulse signal and the low power consumption control pulse signal, so as to analogy. It can be understood that after each signal edge is generated, the control unit 1013 will enter a low-power sleep state. At this time, within a preset cycle of the state control circuit, at the first preset time t1 and the third preset time t3 During the period between, the control unit is timed by the timer; during the period between the third preset time t3 and the fourth preset time t4, the control unit is controlled by the RTC. Since the input clock of the RTC is much lower than that of the timer, the power consumption per unit time of the product can be reduced by controlling the unit to sleep frequently and reducing the clock of the timer.

For other features and beneficial effects of the state control circuit of this embodiment, reference may be made to the relevant content of the implementation manner of the state control device 100 , which will not be repeated here. It can be understood that, according to the embodiment of the present application, various functions of the state control device 100 can be realized by the state control circuit of the present embodiment, but the present application is not limited thereto. The electrical stimulation device, medical device or state control method, and state control circuit in the above-mentioned embodiments can generate periodic control pulse signals in response to treatment instructions by configuring the controller, and the control pulse signals include parameter control pulse signals, treatment control The pulse signal and the low power consumption control pulse signal enable the controller to control the electrical stimulation component to output a periodic preset treatment signal according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal; The period of the preset treatment signal is equal to the period of the parameter control pulse signal, and the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal, so that the product periodically outputs The treatment signal ensures the treatment effect while reducing the energy consumption per unit time of the product. This application does not add additional electronic components or batteries, only by controlling the state of the output signal of the electrical stimulation component of the electrical stimulation device, the energy consumption per unit time of the product is reduced, the working time of the product after charging is improved, the implementation cost is low, and the control The effect is good.

It should be understood that although the steps in the flow charts of FIG. 2 , FIG. 5 and FIG. 9 are shown sequentially as indicated by the arrows, these steps are not necessarily executed sequentially in the order indicated by the arrows. Unless otherwise specified herein, there is no strict order restriction on the execution of these steps, and these steps can be executed in other orders. Moreover, at least some of the steps in Fig. 2, Fig. 5 and Fig. 9 may include a plurality of sub-steps or stages, these sub-steps or stages are not necessarily executed at the same time, but may be executed at different moments, these The execution order of the sub-steps or stages is not necessarily performed sequentially, but may be executed alternately or alternately with at least a part of other steps or sub-steps or stages of other steps.

Those of ordinary skill in the art can understand that all or part of the processes in the methods of the above embodiments can be implemented through computer programs to instruct related hardware, and the computer programs can be stored in a non-volatile computer-readable memory In the medium, when the computer program is executed, it may include the processes of the embodiments of the above-mentioned methods. Wherein, any references to memory, storage, database or other media used in the various embodiments provided in the present application may include at least one of non-volatile memory and volatile memory. Non-volatile memory may include read-only memory (Read-Only Memory, ROM), magnetic tape, floppy disk, flash memory or optical memory, etc. Volatile memory can include Random Access Memory (RAM) or external cache memory. By way of illustration and not limitation, RAM can take many forms, such as Static Random Access Memory (SRAM) or Dynamic Random Access Memory (DRAM).

Please note that the above-mentioned embodiments are for illustrative purposes only and are not meant to limit the present application.

The technical features of the above-mentioned embodiments can be combined arbitrarily. For the sake of concise description, all possible combinations of the technical features of the above-mentioned embodiments are not described. However, as long as there is no contradiction in the combination of these technical features, they should be It is considered to be within the range described in this specification.

The above-mentioned embodiments only express several implementation modes of the present application, and the description thereof is relatively specific and detailed, but should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make several modifications and improvements without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the scope of protection of the patent application should be based on the appended claims.

Claims (35)

1. A state control device for controlling the state of an output signal of an electric stimulation component of an electric stimulation device, the state control device includes a controller connected to the electric stimulation component, and the controller is configured to:

   Generate periodic control pulse signals in response to treatment instructions, the control pulse signals include parameter control pulse signals, treatment control pulse signals and low power consumption control pulse signals;

   According to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal, the electrical stimulation component is controlled to output a periodic preset treatment signal; the period of the preset treatment signal is equal to that of the parameter control pulse signal Period, the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal.
2. The device according to claim 1, wherein the triggering moment of the treatment control pulse signal corresponds to the rising edge, and the triggering moment of the low power consumption control pulse signal is the same as the triggering moment of the treatment control pulse signal and ahead of the The rising edge of the parameter control pulse signal, the trigger moment of the low power consumption control pulse signal corresponds to the falling edge;

   The generation of periodic control pulse signals in response to treatment instructions includes:

   Timing/counting from the triggering moment of the treatment control pulse signal as the starting time, and controlling the treatment control pulse signal to maintain a high level and controlling the low power consumption control pulse signal to maintain a low level;

   triggering the first rising edge of the parameter control pulse signal at a first preset moment;

   triggering the first falling edge of the parameter control pulse signal and the first falling edge of the treatment control pulse signal at a second preset moment;

   triggering the first rising edge of the low power consumption control pulse signal at a third preset moment;

   The second rising edge of the parameter control pulse signal is triggered at a fourth preset moment; wherein, the time difference between the fourth preset moment and the first preset moment is equal to the period of the parameter control pulse signal.
3. The device according to claim 2, wherein the preset treatment signal further comprises a stimulation intermittent waveform;

   The controlling the electrical stimulation component to output a periodic preset treatment signal according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal includes:

   triggering the first rising edge of the preset treatment signal at the first preset moment;

   triggering the first falling edge of the preset treatment signal and the stimulation intermittent waveform at the second preset moment;

   Stopping the stimulation intermittent waveform and triggering the preset low power consumption waveform at the third preset moment;

   At the fourth preset moment, the preset low power consumption waveform is suspended and a second rising edge of the preset therapy signal is triggered.
4. The device according to claim 3, wherein the stimulation intermittent waveform is a low level, and the maximum value of the preset low power consumption waveform is less than or equal to the minimum value of the low level.
5. The device according to any one of claims 1-4, wherein the controller is further configured to:

   The frequency of the internal clock of the controller is obtained, and in response to the treatment instruction, the control pulse signal is generated according to the frequency of the clock.
6. The device according to any one of claims 1-4, wherein the controller is further configured to:

   Acquiring the time set by the preset delay function inside the controller, and generating the control pulse signal according to the time set by the preset delay function.
7. The device according to any one of claims 1-6, further comprising:

   An oscillator, connected to the controller, used to trigger the controller to generate the control pulse signal.
8. The device according to any one of claims 1-7, wherein the parameter control pulse signal includes a wake-up interrupt signal; the controller is further configured to:

   Obtain the cycle of the wake-up interrupt signal;

   The control pulse signal is generated according to a period of the wake-up interrupt signal in response to the therapy instruction.
9. The device according to any one of claims 1-8, wherein the treatment instruction includes an instruction for setting at least one of the cycle, pulse width, and duration of the preset low-power waveform of the preset treatment signal. Preset parameters.
10. The device according to any one of claims 1-9, wherein the controller is further configured to:

    The treatment instruction from the terminal device is acquired, and a control pulse signal including the preset parameters is generated according to the treatment instruction.
11. An electrical stimulation device, comprising:

    electrical stimulation components; and

    The state control device according to any one of claims 1-10.
12. The electrical stimulation device of claim 10, further comprising:

    a communication module connected to the controller;

    Wherein, the controller obtains the treatment instructions and/or configuration parameters from the terminal equipment through the communication module, and the configuration parameters include the period, pulse width and duration of the preset low power consumption waveform of the preset treatment signal. At least one of the times.
13. The electrical stimulation device according to claim 12, wherein the communication module comprises:

    Bluetooth module, connected with the controller;

    Wherein, the controller obtains the treatment instruction and/or the configuration parameters through the Bluetooth module.
14. The electro-stimulation device according to any one of claims 11-13, wherein the electro-stimulation assembly comprises a plurality of electrodes connected to the controller.
15. The electro-stimulation device according to any one of claims 11-14, wherein the electro-stimulation device is an implantable electro-stimulation device.
16. A medical device, comprising:

    An electrostimulation device as claimed in any one of claims 11-15.
17. A state control method, wherein, be applied to the state control device described in any one of claims 1-10; Said method comprises:

    Generate periodic control pulse signals in response to treatment instructions, the control pulse signals include parameter control pulse signals, treatment control pulse signals and low power consumption control pulse signals;

    According to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal, the electrical stimulation component is controlled to output a periodic preset treatment signal; the period of the preset treatment signal is equal to that of the parameter control pulse signal Period, the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal.
18. The method according to claim 17, further comprising:

    The trigger time of the treatment control pulse signal is set to correspond to the rising edge, and the trigger time of the low power consumption control pulse signal is set to be the same as the trigger time of the treatment control pulse signal and ahead of the rising edge of the parameter control pulse signal, Setting the trigger time of the low power consumption control pulse signal to correspond to the falling edge;

    Wherein, the generation of periodic control pulse signals in response to treatment instructions includes:

    Timing/counting from the triggering moment of the treatment control pulse signal as the starting time, and controlling the treatment control pulse signal to maintain a high level and controlling the low power consumption control pulse signal to maintain a low level;

    triggering the first rising edge of the parameter control pulse signal at a first preset moment;

    triggering the first falling edge of the parameter control pulse signal and the first falling edge of the treatment control pulse signal at a second preset moment;

    triggering the first rising edge of the low power consumption control pulse signal at a third preset moment;

    The second rising edge of the parameter control pulse signal is triggered at a fourth preset moment; wherein, the time difference between the fourth preset moment and the first preset moment is equal to the period of the parameter control pulse signal.
19. The method according to claim 18, wherein the preset treatment signal further comprises a stimulation intermittent waveform;

    The controlling the electrical stimulation component to output a periodic preset treatment signal according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal includes:

    triggering the first rising edge of the preset treatment signal at the first preset moment;

    triggering the first falling edge of the preset treatment signal and the stimulation intermittent waveform at the second preset moment;

    Stopping the stimulation intermittent waveform and triggering the preset low power consumption waveform at the third preset moment;

    At the fourth preset moment, the preset low power consumption waveform is suspended and a second rising edge of the preset therapy signal is triggered.
20. The method according to claim 19, wherein the stimulation intermittent waveform is a low level, and the maximum value of the preset low power consumption waveform is less than or equal to the minimum value of the low level.
21. The method according to any one of claims 17-20, further comprising:

    The frequency of the internal clock of the controller is obtained, and in response to the treatment instruction, the control pulse signal is generated according to the frequency of the clock.
22. The method according to any one of claims 17-20, further comprising:

    Acquiring the time set by the preset delay function inside the controller, and generating the control pulse signal according to the time set by the preset delay function.
23. The method according to any one of claims 17-22, further comprising:

    set the oscillator connected with the controller,

    The oscillator is used to trigger the controller to generate the control pulse signal.
24. The method according to any one of claims 17-23, wherein the parameter control pulse signal includes a wake-up interrupt signal; the method further includes:

    Obtain the cycle of the wake-up interrupt signal;

    The control pulse signal is generated according to a period of the wake-up interrupt signal in response to the therapy instruction.
25. The method according to any one of claims 17-24, wherein the treatment instruction includes at least one of the parameters for setting the period, pulse width and duration of the preset low-power waveform of the preset treatment signal Preset parameters.
26. The method according to any one of claims 17-25, further comprising:

    The treatment instruction from the terminal device is acquired, and a control pulse signal including the preset parameters is generated according to the treatment instruction.
27. A state control circuit, used to control the state of the output signal of the electric stimulation component of the electric stimulation device, the state control circuit includes a control pulse signal generation module and a preset treatment signal generation module; wherein,

    The control pulse signal generation module includes a control unit, the control unit is configured to generate a periodic control pulse signal in response to a treatment instruction, and the control pulse signal includes a parameter control pulse signal, a treatment control pulse signal and a low power consumption control pulse signal. Pulse signal;

    The preset treatment signal generation module is configured to control the electrical stimulation component to output a periodic preset treatment signal according to the parameter control pulse signal, treatment control pulse signal and low power consumption control pulse signal; the preset treatment The period of the signal is equal to the period of the parameter control pulse signal, and the preset treatment signal includes a preset low power consumption waveform and a stimulation pulse with the same pulse width as the parameter control pulse signal.
28. The state control circuit according to claim 27, wherein the preset treatment signal generating module comprises a first enabling unit, a second enabling unit and a third enabling unit;

    One end of the first enabling unit, the second enabling unit, and the third enabling unit are respectively connected to the control unit, and the other ends are respectively connected to the electrical stimulation component, and are used for respectively according to the parameters The control pulse signal, the treatment control pulse signal and the low power consumption control pulse signal control the electrical stimulation component to output a periodic preset treatment signal.
29. The state control circuit according to claim 28, wherein,

    The first enable unit includes a first switch, an operational amplifier, a MOS tube, and a current sampling resistor; the first end of the first switch is connected to the control unit, configured to receive the parameter control pulse signal as an enable signal; the second end of the first switch is connected to the first input end of the operational amplifier, and the first input end of the operational amplifier is connected to the output of the digital-to-analog converter through the third end of the first switch end, the second input end of the operational amplifier is connected to the current sampling resistor; the output end of the operational amplifier is connected to the first end of the electrical stimulation component via the MOS transistor and the first capacitor, and the MOS transistor The grid of the current sampling resistor is connected to the ground terminal.
30. The state control circuit of claim 29, wherein the first switch further comprises a third terminal connected to a power source.
31. The state control circuit according to claim 28, wherein,

    The second enabling unit includes a second switch and a second capacitor for energy storage; the first end of the second switch is connected to the control unit, configured to receive the treatment control pulse signal as an enabling signal ; The second terminal of the second switch is respectively connected to the second capacitor and the third capacitor, and is connected to the second terminal of the electrical stimulation component via the third capacitor.
32. The state control circuit of claim 31, wherein the second switch further includes a third terminal connected to a power source.
33. The state control circuit according to claim 28, wherein,

    The third enabling unit includes a third switch, a third capacitor and a first capacitor, the first end of the third switch is connected to the control unit, configured to receive the low power consumption control pulse signal as an enabling signal; the third switch is also connected across the two ends of the electrical stimulation component, and respectively connected to the first end of the electrical stimulation component via the first capacitor, and connected to the electrical stimulation component via the third capacitor the second end of the component.
34. The state control circuit according to claim 33, wherein,

    One end of the third switch connected to the second end of the electrical stimulation component is also connected to a power source.
35. The state control circuit according to any one of claims 27-34, wherein the trigger time of the treatment control pulse signal corresponds to the rising edge, and the trigger time of the low power consumption control pulse signal is the same as that of the treatment control pulse signal. The triggering time is the same and ahead of the rising edge of the parameter control pulse signal, and the triggering time of the low power consumption control pulse signal corresponds to the falling edge;

    The control unit generates periodic control pulse signals in response to treatment instructions, including:

    Timing/counting from the triggering moment of the treatment control pulse signal as the starting time, and controlling the treatment control pulse signal to maintain a high level and controlling the low power consumption control pulse signal to maintain a low level;

    triggering the first rising edge of the parameter control pulse signal at a first preset moment;

    triggering the first falling edge of the parameter control pulse signal and the first falling edge of the treatment control pulse signal at a second preset moment;

    triggering the first rising edge of the low power consumption control pulse signal at a third preset moment;

    The second rising edge of the parameter control pulse signal is triggered at a fourth preset moment; wherein, the time difference between the fourth preset moment and the first preset moment is equal to the period of the parameter control pulse signal.

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