WO2023036296A1 - Capsule d'administration de médicament - Google Patents
Capsule d'administration de médicament Download PDFInfo
- Publication number
- WO2023036296A1 WO2023036296A1 PCT/CN2022/118123 CN2022118123W WO2023036296A1 WO 2023036296 A1 WO2023036296 A1 WO 2023036296A1 CN 2022118123 W CN2022118123 W CN 2022118123W WO 2023036296 A1 WO2023036296 A1 WO 2023036296A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drug delivery
- drug
- capsule
- housing
- inlet
- Prior art date
Links
- 239000002775 capsule Substances 0.000 title claims abstract description 50
- 238000001647 drug administration Methods 0.000 title claims abstract description 29
- 239000003814 drug Substances 0.000 claims abstract description 107
- 229940079593 drug Drugs 0.000 claims abstract description 68
- 239000007901 soft capsule Substances 0.000 claims abstract description 56
- 239000012530 fluid Substances 0.000 claims abstract description 24
- 238000012377 drug delivery Methods 0.000 claims description 80
- 238000003384 imaging method Methods 0.000 claims description 31
- 238000005192 partition Methods 0.000 claims description 12
- 238000001125 extrusion Methods 0.000 claims description 4
- 210000001035 gastrointestinal tract Anatomy 0.000 description 10
- 238000009434 installation Methods 0.000 description 9
- 239000007788 liquid Substances 0.000 description 9
- 230000003902 lesion Effects 0.000 description 6
- 238000013461 design Methods 0.000 description 5
- 208000025865 Ulcer Diseases 0.000 description 4
- 230000001079 digestive effect Effects 0.000 description 4
- 230000033001 locomotion Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- 238000004891 communication Methods 0.000 description 3
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 3
- 239000012535 impurity Substances 0.000 description 3
- 238000013270 controlled release Methods 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241000167880 Hirundinidae Species 0.000 description 1
- 208000008469 Peptic Ulcer Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000001839 endoscopy Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000004643 material aging Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000011906 peptic ulcer disease Diseases 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Definitions
- the drug delivery capsule also has an imaging module arranged in the cavity of the device, and the drug delivery channel includes a drug delivery outlet arranged on the housing; the drug delivery outlet is arranged on the imaging module. within the image acquisition area of the module.
- Embodiments of the present invention a drug delivery capsule is disclosed.
- the drug delivery capsule has a drug storehouse for storing medicine.
- the drug stored in the drug storehouse enters the digestive tract section along with the drug delivery capsule. When it reaches the delivery area It is released after the lesion area, so as to achieve precise drug delivery.
- the imaging module 5 includes a module circuit board 51 arranged in the equipment cavity 12, a camera 52 arranged on the module circuit board 51, and a supplementary camera 52 arranged on the side of the camera 52.
- Light 53 The number of the supplementary lights 53 can be multiple, and the multiple supplementary lights 53 are arranged around the camera 52 .
- the module circuit board 51 is electrically connected to the battery unit 41 , and the battery unit 41 supplies power to the imaging module 5 .
- the pump body 31 is arranged on the partition 13, and the partition 13 is provided with a connection hole connecting the medicine compartment 10 and the equipment cavity 12 , the outlet of the pump body 31 communicates with the connecting hole.
- the outlet of the pump body 31 is directly exposed to the drug storehouse 10 to facilitate the release of the controlled fluid into the drug storehouse 10 .
- the drug delivery capsule is extended along the length direction, and the soft capsule 11 and the imaging module 5 are arranged oppositely on both sides of the housing 1 in the length direction; the drug delivery outlet 21 It is arranged on the side of the housing 1 away from the soft capsule 11; the administration channel 2 also has an administration inlet 22 arranged on the soft capsule 11 and communicates with the administration inlet 22 and the
- the connection pipe 23 of the drug delivery outlet 21, the connection pipe 23 is a hose.
- the hose can be made of biocompatible PC material.
- the drug delivery outlet 21 is arranged in the image acquisition area of the imaging module 5, so that the imaging module 5 can directly observe the drug delivery status, so as to better control the drug delivery.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
L'invention concerne une capsule d'administration de médicament. La capsule d'administration de médicament est pourvue d'un boîtier (1) avec une cartouche de médicament (10), d'une capsule molle (11) disposée dans la cartouche de médicament (10), d'un canal d'administration de médicament (2), et d'un module de contrôle d'administration de médicament (3). Le module de contrôle d'administration de médicament (3) est utilisé pour remplir la cartouche de médicament (10) avec un fluide pour extruder la capsule molle (11), de telle sorte que l'administration de médicament est effectuée d'une manière de remplacement. Le module de contrôle d'administration de médicament peut être utilisé pour contrôler la quantité d'administration de médicament au moyen du contrôle de la quantité de fluide entrant dans la cartouche de médicament (10), et la vitesse d'administration de médicament est contrôlée au moyen du contrôle de la vitesse du fluide entrant dans la cartouche de médicament (10).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2024515287A JP2024530818A (ja) | 2021-09-10 | 2022-09-09 | 投薬カプセル |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111060451.0 | 2021-09-10 | ||
CN202111060451.0A CN113769249B (zh) | 2021-09-10 | 2021-09-10 | 一种给药胶囊 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2023036296A1 true WO2023036296A1 (fr) | 2023-03-16 |
Family
ID=78842402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2022/118123 WO2023036296A1 (fr) | 2021-09-10 | 2022-09-09 | Capsule d'administration de médicament |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP2024530818A (fr) |
CN (1) | CN113769249B (fr) |
WO (1) | WO2023036296A1 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113769249B (zh) * | 2021-09-10 | 2023-08-04 | 安翰科技(武汉)股份有限公司 | 一种给药胶囊 |
CN114376980B (zh) * | 2022-01-14 | 2024-05-03 | 安翰科技(武汉)股份有限公司 | 施药胶囊 |
CN116350275A (zh) * | 2023-03-07 | 2023-06-30 | 安翰科技(武汉)股份有限公司 | 采样胶囊、采集方法 |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002186672A (ja) * | 2001-09-28 | 2002-07-02 | Olympus Optical Co Ltd | 医療用カプセル装置 |
CN1730118A (zh) * | 2005-08-19 | 2006-02-08 | 华南理工大学 | 化学反应气压式微胶囊药物释放方法及其装置 |
US20080234546A1 (en) * | 2003-10-01 | 2008-09-25 | Olympus Corporation | In vivo observation device |
CN101301508A (zh) * | 2008-06-27 | 2008-11-12 | 华南理工大学 | 利用超声触发控制的化学反应气压式肠胃道药物释放装置 |
CN102139137A (zh) * | 2011-03-04 | 2011-08-03 | 上海交通大学 | 基于数字图像导航的体外磁控制药物释放胶囊系统 |
CN106730284A (zh) * | 2016-11-24 | 2017-05-31 | 上海理工大学 | 微胶囊式胃肠道药物释放系统 |
EP3189819A1 (fr) * | 2016-01-11 | 2017-07-12 | Raumedic AG | Dispositif de distribution de médicaments et module de distribution de médicaments |
CN108968924A (zh) * | 2018-05-28 | 2018-12-11 | 重庆大学 | 一种出血释药胶囊 |
CN113769249A (zh) * | 2021-09-10 | 2021-12-10 | 安翰科技(武汉)股份有限公司 | 一种给药胶囊 |
CN113769250A (zh) * | 2021-09-10 | 2021-12-10 | 安翰科技(武汉)股份有限公司 | 一种给药胶囊 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4180073A (en) * | 1977-08-29 | 1979-12-25 | Alza Corporation | Device for delivering drug to biological environment |
US8852083B2 (en) * | 2005-02-04 | 2014-10-07 | Uti Limited Partnership | Self-stabilized encapsulated imaging system |
US8114055B2 (en) * | 2005-05-10 | 2012-02-14 | Palyon Medical (Bvi) Limited | Implantable pump with infinitely variable resistor |
DE602009001050D1 (de) * | 2008-06-04 | 2011-05-26 | Olympus Medical Systems Corp | Kapselförmige medizinische Vorrichtung |
JP5203050B2 (ja) * | 2008-06-04 | 2013-06-05 | オリンパスメディカルシステムズ株式会社 | カプセル型医療装置 |
EP3603624A1 (fr) * | 2009-12-24 | 2020-02-05 | Rani Therapeutics, LLC | Préparations d'agent thérapeutique pour l'administration dans une lumière du tractus intestinal à l'aide d'un dispositif d'administration de médicaments à avaler |
US10064544B2 (en) * | 2015-01-26 | 2018-09-04 | The Chinese University Of Hong Kong | Endoscopic capsule and endoscopic system |
CN207152881U (zh) * | 2017-03-14 | 2018-03-30 | 华北石油管理局总医院 | 一种喷涂式食道上药装置 |
CA3092688A1 (fr) * | 2018-03-01 | 2019-09-06 | Minipumps Llc | Pompes a flux continu implantables |
CN211911674U (zh) * | 2020-01-19 | 2020-11-13 | 安翰科技(武汉)股份有限公司 | 胶囊系统 |
CN111631674A (zh) * | 2020-06-03 | 2020-09-08 | 湖北科技学院 | 一种释药型胶囊式消化道内窥镜装置及释药方法 |
CN113080809A (zh) * | 2021-03-10 | 2021-07-09 | 中国矿业大学 | 一种基于磁流变液的软体医疗胶囊机器人 |
-
2021
- 2021-09-10 CN CN202111060451.0A patent/CN113769249B/zh active Active
-
2022
- 2022-09-09 WO PCT/CN2022/118123 patent/WO2023036296A1/fr active Application Filing
- 2022-09-09 JP JP2024515287A patent/JP2024530818A/ja active Pending
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002186672A (ja) * | 2001-09-28 | 2002-07-02 | Olympus Optical Co Ltd | 医療用カプセル装置 |
US20080234546A1 (en) * | 2003-10-01 | 2008-09-25 | Olympus Corporation | In vivo observation device |
CN1730118A (zh) * | 2005-08-19 | 2006-02-08 | 华南理工大学 | 化学反应气压式微胶囊药物释放方法及其装置 |
CN101301508A (zh) * | 2008-06-27 | 2008-11-12 | 华南理工大学 | 利用超声触发控制的化学反应气压式肠胃道药物释放装置 |
CN102139137A (zh) * | 2011-03-04 | 2011-08-03 | 上海交通大学 | 基于数字图像导航的体外磁控制药物释放胶囊系统 |
EP3189819A1 (fr) * | 2016-01-11 | 2017-07-12 | Raumedic AG | Dispositif de distribution de médicaments et module de distribution de médicaments |
CN106730284A (zh) * | 2016-11-24 | 2017-05-31 | 上海理工大学 | 微胶囊式胃肠道药物释放系统 |
CN108968924A (zh) * | 2018-05-28 | 2018-12-11 | 重庆大学 | 一种出血释药胶囊 |
CN113769249A (zh) * | 2021-09-10 | 2021-12-10 | 安翰科技(武汉)股份有限公司 | 一种给药胶囊 |
CN113769250A (zh) * | 2021-09-10 | 2021-12-10 | 安翰科技(武汉)股份有限公司 | 一种给药胶囊 |
Also Published As
Publication number | Publication date |
---|---|
CN113769249A (zh) | 2021-12-10 |
JP2024530818A (ja) | 2024-08-23 |
CN113769249B (zh) | 2023-08-04 |
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