WO2023016378A1

WO2023016378A1 - Blood pressure measurement method and apparatus, and electronic device

Info

Publication number: WO2023016378A1
Application number: PCT/CN2022/110645
Authority: WO
Inventors: 刘子毅; 潘伟潮
Original assignee: 广东乐心医疗电子股份有限公司
Priority date: 2021-08-07
Filing date: 2022-08-05
Publication date: 2023-02-16
Also published as: WO2023016326A1

Abstract

The present disclosure provides a blood pressure measurement method and apparatus, and an electronic device. The method comprises: applying pressure to a first part of a user, and acquiring blood pressure multi-modal information of the user, the blood pressure multi-modal information comprising a first pulse wave signal generated by the first part of the user and a second pulse wave signal generated by a second part of the user; and performing weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain a blood pressure measurement value of the user, the blood pressure measurement value comprising a systolic pressure measurement value and a diastolic pressure measurement value. In this mode, two pulse wave signals can be acquired and are subjected to weighted calculation to obtain the blood pressure measurement value of the user, which can reduce the influence of signal quality and improve the accuracy of blood pressure measurement.

Description

Blood pressure measurement method, device and electronic equipment

Cross References to Related Applications

This disclosure requires that the Chinese patent application with the application number 202110904954.5 titled "Blood Pressure Measurement Method, Device and Electronic Equipment" be submitted to the State Intellectual Property Office of China on August 7, 2021, and that the Chinese National Intellectual Property Office be submitted on August 7, 2021. Priority of Chinese Patent Application No. 202110904953.0 entitled "Blood Pressure Calibration Method, Apparatus, System, and Electronic Equipment" from the Intellectual Property Office, the entire contents of which are incorporated by reference in this disclosure.

technical field

The present disclosure relates to the field of medical technology, in particular to a blood pressure measuring method, device and electronic equipment.

Background technique

The electronic sphygmomanometer currently used clinically is mainly based on the oscillometric method to measure the user's blood pressure. The arterial vessel is blocked by pressure from the cuff, and the envelope of the oscillating wave from the vessel wall is sensed during inflation or deflation. Based on the statistical law, the envelope shape and the corresponding relationship between the user's systolic blood pressure and diastolic blood pressure are found, and the blood pressure measurement value is obtained.

However, this method of single-use oscillometric measurement is easily constrained by statistical laws, that is, statistical laws do not necessarily satisfy the individual specificity of a small number of users. At the same time, it may also be affected by the signal quality, resulting in low measurement accuracy.

Contents of the invention

In view of this, the purpose of the present disclosure is to provide a blood pressure measurement method, device and electronic equipment, so as to reduce the influence of signal quality and improve the accuracy of blood pressure measurement.

An embodiment of the present disclosure provides a method for measuring blood pressure. The method may include: applying pressure to the first part of the user, and acquiring multimodal information of the user's blood pressure; wherein the multimodal information of blood pressure includes information generated by the first part of the user. The first pulse wave signal of the user and the second pulse wave signal generated by the second part of the user; the weighted average calculation is performed on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user; wherein, the blood pressure measurement value includes Systolic and diastolic measurements.

In an optional embodiment of the present disclosure, the above-mentioned step of applying pressure to the first part of the user and obtaining the multimodal information of the user's blood pressure may include: applying pressure to the first part of the user through the first pulse wave detection module ; The first pulse wave signal generated by the first part of the user is detected by the first pulse wave detection module; the second pulse wave signal generated by the second part of the user is detected by the second pulse wave detection module.

In an optional embodiment of the present disclosure, the above-mentioned first pulse wave detection module and the second pulse wave detection module may be set on the same side arm of the user; the first part of the user may be the proximal artery of the user's arm ; The second part of the user may be the distal artery of the user's arm.

In an optional embodiment of the present disclosure, the above-mentioned first pulse wave detection module may include an oscillometric-based arm or wrist electronic sphygmomanometer; the second pulse wave detection module may include at least one of the following: photoplethysmography scanning meter, laser radar, optical imager, piezoelectric sensor or capacitive sensor; the step of performing weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user may include: The processor of the meter performs weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user.

In the disclosed embodiment of the present disclosure, the measurement method of the electronic sphygmomanometer may include inflation measurement and deflation measurement; when the measurement method of the electronic sphygmomanometer is inflation measurement, the pulse wave main wave amplitude and The amplitude of the dicrotic wave can change from large to small over time until the user's arterial blood vessel is blocked and becomes a stable process; when the electronic sphygmomanometer is measured in deflated mode, the amplitude of the main pulse wave of the second pulse wave signal And the dicrotic wave amplitude can be: from a stable process after the user's arterial vessel is blocked, to a process from small to large over time.

In an optional embodiment of the present disclosure, the step of performing weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user may include: obtaining the characteristics of the first pulse wave signal and the second pulse wave signal Two features of the pulse wave signal; wherein, the feature can at least include: the main wave starting moment, the main wave peak time, the main wave amplitude, the descending gorge time, the dicrotic wave peak time, the heavy wave Pulse wave amplitude, dicrotic wave end time; based on the characteristics of the first pulse wave signal and the second pulse wave signal, weighted average calculation is performed on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user.

In an optional embodiment of the present disclosure, the weighted average calculation is performed on the first pulse wave signal and the second pulse wave signal based on the characteristics of the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user The step may include: based on the characteristics of the first pulse wave signal, using the variable amplitude coefficient method to determine the user's average blood pressure measurement value MAP, the first systolic blood pressure measurement value _SBP1 and the first diastolic blood pressure measurement value _DBP1 ; based on the second The characteristics of the pulse wave signal, the pressure corresponding to the initial moment of the stable process during the inflation type measurement or the end point of the stable process during the deflation type measurement is used as the second systolic blood pressure measurement value SBP ₂ ; the second pulse wave signal The characteristics and mean pressure measurement value MAP, input the preset second diastolic pressure model, output the second diastolic pressure measurement value _DBP2 ; weighted average of the first systolic pressure measurement value _SBP1 and the second systolic pressure measurement value _SBP2 Calculate to obtain the user's systolic blood pressure measurement value SBP; perform weighted average calculation on the first diastolic blood pressure measurement value DBP ₁ and the second diastolic blood pressure measurement value DBP ₂ to obtain the user's diastolic blood pressure measurement value DBP.

In an optional embodiment of the present disclosure, the weighted average calculation of the first systolic blood pressure measurement value SBP ₁ and the second systolic blood pressure measurement value SBP ₂ to obtain the user's systolic blood pressure measurement value SBP may include: The first weight value and the second weight value perform weighted average calculation on the first systolic blood pressure measurement value SBP ₁ and the second systolic blood pressure measurement value SBP ₂ to obtain the user's systolic blood pressure measurement value SBP; for the first diastolic blood pressure measurement value DBP ₁ The step of performing weighted average calculation with the second diastolic blood pressure measurement DBP ₂ to obtain the user's diastolic blood pressure measurement DBP includes: based on the preset third weight value and the fourth weight value, the first diastolic blood pressure measurement value DBP ₁ and The weighted average calculation is performed on the second diastolic blood pressure measurement value DBP ₂ to obtain the user's diastolic blood pressure measurement value DBP.

In an optional embodiment of the present disclosure, the above method may further include: determining invalid first pulse wave signals in the first pulse wave signal and the second pulse wave signal based on the characteristics of the first pulse wave signal and the characteristics of the second pulse wave signal, respectively. Pulse wave and invalid second pulse wave; delete invalid first pulse wave and invalid second pulse wave; count the first proportion of invalid first pulse wave in the first pulse wave signal and the invalid second pulse wave in the second pulse wave The second proportion in the wave signal; calculate the signal quality of the first pulse wave based on the characteristics of the first pulse wave signal and the first proportion; calculate the signal quality of the second pulse wave based on the characteristics of the second pulse wave signal and the second proportion Signal quality; determining the weight of the first pulse wave signal and the weight of the second pulse wave signal based on the signal quality of the first pulse wave and the signal quality of the second pulse wave; for the first systolic blood pressure measurement value SBP ₁ and the second systolic blood pressure The step of performing weighted average calculation on the measured value SBP ₂ to obtain the user's systolic blood pressure measured value SBP may include: calculating the first systolic blood pressure measured value SBP ₁ and the second pulse wave signal through the weight of the first pulse wave signal and the weight of the second pulse wave signal Perform weighted average calculation on the two systolic blood pressure measurement values SBP ₂ to obtain the user's systolic blood pressure measurement value SBP; perform weighted average calculation on the first diastolic blood pressure measurement value DBP ₁ and the second diastolic blood pressure measurement value DBP ₂ to obtain the user's diastolic blood pressure measurement value The step of calculating the DBP may include: performing weighted average calculation on the first diastolic pressure measurement value and the second diastolic pressure measurement value through the weight of the first pulse wave signal and the weight of the second pulse wave signal to obtain the user's diastolic pressure measurement value .

In an optional embodiment of the present disclosure, the above step of determining the weight of the first pulse wave signal and the weight of the second pulse wave signal based on the signal quality of the first pulse wave and the signal quality of the second pulse wave may include: if The signal quality of the first pulse wave is less than the preset first threshold, the weight of the first pulse wave signal is 0, and the weight of the second pulse wave signal is 1; if the signal quality of the second pulse wave is less than the preset second threshold , the weight of the second pulse wave signal is 0, and the weight of the first pulse wave signal is 1; if the difference between the signal quality of the first pulse wave and the signal quality of the second pulse wave is greater than the preset threshold, the weight of the first pulse wave The weight is 1, and the weight of the second pulse wave is 0.

In an optional embodiment of the present disclosure, the above method may further include: if the peak moment of the main wave of the second pulse wave signal is missing at the peak moment of the first main wave signal of the first pulse wave signal, based on the time before and after the peak moment of the first main wave signal The characteristics of multiple second pulse wave signals reconstruct the characteristics of the missing pulse wave corresponding to the first main wave peak moment of the second pulse wave signal; if the first pulse wave is missing at the second main wave peak moment of the second pulse wave signal At the peak time of the main wave, based on the features of the multiple first pulse wave signals before and after the peak time of the second main wave, the characteristics of the missing pulse wave corresponding to the first pulse wave signal at the peak time of the second main wave are reconstructed.

In an optional embodiment of the present disclosure, after the above-mentioned step of applying pressure to the first part of the user, the method may further include: acquiring other physiological signals of the user, and the other physiological signals may include at least one of the following: electrocardiogram signal, photoelectric Plethysmography signal, lidar signal, optical imaging signal, piezoelectric sensor signal or capacitive sensor signal; features of the missing first pulse wave signal and features of the missing second pulse wave signal are analyzed by other physiological signals Reconfiguration; after the step of obtaining the user's blood pressure measurement value, the method may further include: compensating the user's blood pressure measurement value through other physiological signals, and obtaining the user's blood pressure measurement value after compensation.

An embodiment of the present disclosure also provides a blood pressure measurement device, which may include: a multimodal information acquisition module configured to apply pressure to the first part of the user to acquire multimodal information of the user's blood pressure; wherein, The blood pressure multimodal information includes the first pulse wave signal generated by the first part of the user and the second pulse wave signal generated by the second part of the user; the weighted average calculation module is configured to calculate the first pulse wave signal and the second pulse wave signal The weighted average calculation is performed on the two pulse wave signals to obtain the blood pressure measurement value of the user; wherein, the blood pressure measurement value includes a systolic blood pressure measurement value and a diastolic blood pressure measurement value.

In an optional embodiment of the present disclosure, the multimodal information acquisition module may be configured to apply pressure to the first part of the user through the first pulse wave detection module; The first pulse wave signal generated by the part; the second pulse wave signal generated by the second part of the user is detected by the second pulse wave detection module.

In an optional embodiment of the present disclosure, the above-mentioned first pulse wave detection module may include an oscillometric-based arm or wrist electronic sphygmomanometer; the second pulse wave detection module may include at least one of the following: photoplethysmography scanning meter, laser radar, optical imager, piezoelectric sensor or capacitive sensor; the above weighted average calculation module can be configured to weight the first pulse wave signal and the second pulse wave signal through the processor of the electronic sphygmomanometer Calculate the average to obtain the user's blood pressure measurement value.

In an optional embodiment of the present disclosure, the measurement method of the electronic sphygmomanometer may include inflation measurement and deflation measurement; when the measurement method of the electronic sphygmomanometer is inflation measurement, the pulse wave main wave amplitude of the second pulse wave signal And the amplitude of the dicrotic wave can change from large to small over time until the user's arterial blood vessel is blocked and evolves into a stable process; The amplitude and the dicrotic wave amplitude can be: from a stable process after the user's arteries are blocked, to a process that changes from small to large over time.

An embodiment of the present disclosure also provides an electronic device, including a processor and a memory, the memory stores computer-executable instructions that can be executed by the processor, and when the electronic device is running, the processor executes the computer-executable instructions, In order to realize the above blood pressure measuring method.

An embodiment of the present disclosure also provides a computer-readable storage medium, on which computer-executable instructions are stored, and when the computer-executable instructions are invoked and executed by a processor, the processor is prompted to implement the above blood pressure measurement method .

An embodiment of the present disclosure also provides a computer program product, including a computer program that, when invoked and executed by a processor, prompts the processor to implement the above blood pressure measurement method.

Embodiments of the present disclosure bring the following beneficial effects:

The embodiments of the present disclosure provide a blood pressure measurement method, device, and electronic equipment, which can obtain the first pulse wave signal generated by the first part of the user and the second pulse wave signal generated by the second part of the user after the pressure is applied to the first part of the user. For the second pulse wave signal, weighted average calculation is performed on the first pulse wave signal and the second pulse wave signal to obtain the user's systolic blood pressure measurement value and diastolic blood pressure measurement value. In this way, two pulse wave signals can be obtained and weighted to calculate the user's blood pressure measurement value, which can reduce the influence of signal quality and improve the accuracy of blood pressure measurement.

Other features and advantages of the present disclosure will be set forth in the following description, or some of the features and advantages can be inferred or unambiguously determined from the description, or can be known by implementing the above-mentioned techniques of the present disclosure.

In order to make the above-mentioned objects, features and advantages of the present disclosure more comprehensible, preferred embodiments will be described in detail below together with the accompanying drawings.

Description of drawings

In order to more clearly illustrate the specific embodiments of the present disclosure or the technical solutions in the prior art, the following will briefly introduce the drawings that need to be used in the description of the specific embodiments or the prior art. Obviously, the accompanying drawings in the following description The drawings are some implementations of the present disclosure, and those skilled in the art can also obtain other drawings according to these drawings without creative work.

FIG. 1 is a flow chart of a method for measuring blood pressure provided by an embodiment of the present disclosure;

FIG. 2 is a flow chart of another blood pressure measurement method provided by an embodiment of the present disclosure;

FIG. 3 is a schematic diagram of a first pulse wave signal and a second pulse wave signal provided by an embodiment of the present disclosure;

FIG. 4 is a schematic diagram of a blood pressure measurement method provided by an embodiment of the present disclosure;

FIG. 5 is a schematic diagram of a blood pressure measurement device provided by an embodiment of the present disclosure;

FIG. 6 is a schematic diagram of another blood pressure measuring device provided by an embodiment of the present disclosure;

FIG. 7 is a schematic diagram of another blood pressure measurement device provided by an embodiment of the present disclosure;

FIG. 8 is a schematic structural diagram of a blood pressure measurement device provided by an embodiment of the present disclosure;

FIG. 9 is a schematic structural diagram of an electronic device provided by an embodiment of the present disclosure.

Icons: 31-the first pulse wave detection module; 32-display screen; 33-user buttons; 34-gas circuit; 35-cuff; 36-second pulse wave detection module; 37-miniature laser source; 38-photodiode ;39-ECG signal detection module; 41-the first pulse wave detection module; 42-display screen; 43-user buttons; 44-gas circuit; 45-cuff; 46-second pulse wave detection module; 48-and photodiode; 49-first pulse wave detection module; 50-display screen; 51-user button; 52-cuff; 53-miniature laser source; 54-photodiode; 55-second pulse wave detection module; 100-memory; 101-processor; 102-bus; 103-communication interface.

Detailed ways

In order to make the purpose, technical solutions and advantages of the embodiments of the present disclosure clearer, the technical solutions of the present disclosure will be clearly and completely described below in conjunction with the accompanying drawings. Apparently, the described embodiments are part of the embodiments of the present disclosure, not all of them. the embodiment. Based on the embodiments in the present disclosure, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present disclosure.

At present, only using the oscillometric method to measure blood pressure is easily affected by the signal quality, resulting in low measurement accuracy. Based on this, the embodiments of the present disclosure provide a blood pressure measurement method, device, and electronic equipment, and specifically relate to a blood pressure measurement method and device that integrates multiple pulse wave signals, which can improve the accuracy of the electronic blood pressure monitor, and is used to enhance the Improvement of accuracy when measuring blood pressure with a single pulse wave signal.

In order to facilitate understanding of this embodiment, a method for measuring blood pressure disclosed in an embodiment of the present disclosure is firstly introduced in detail.

An embodiment of the present disclosure provides a blood pressure measurement method. Referring to the flowchart of a blood pressure measurement method shown in FIG. 1 , the blood pressure measurement method includes the following steps:

Step S102, apply pressure to the first part of the user, and obtain the multimodal information of the user's blood pressure; wherein, the multimodal information of blood pressure includes the first pulse wave signal generated by the first part of the user and the pulse wave signal generated by the second part of the user. Second pulse wave signal.

In order to measure blood pressure, it is first necessary to apply pressure to the first part of the user, wherein the first part can refer to the brachial artery or radial artery of the user's arm, and then the first pulse wave signal generated by the first part can be obtained. The second part can be any position from the first part to the fingertip on the same arm as the first part, for example: the first part is the brachial artery of the user's arm, then the second part can be any position from the brachial artery to the fingertip One location; the first location is the radial artery of the user's arm, and the second location can be any location from the radial artery to the fingertip.

That is, when pressure is applied to the first part of the user, the first part can generate a first pulse wave signal, and the second part can generate a second pulse wave signal, and the above-mentioned first pulse wave signal and second pulse wave signal can be obtained .

Step S104, performing weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the user's blood pressure measurement value; wherein, the blood pressure measurement value includes a systolic blood pressure measurement value and a diastolic blood pressure measurement value.

The weighted average calculation can set different weights for the first pulse wave signal and the second pulse wave signal, and calculate according to the set weight, the first pulse wave signal and the second pulse wave signal, and obtain the user's systolic blood pressure measurement value and diastolic blood pressure Measurements.

Optionally, the above weights may be preset by the user, or calculated by the system based on the first pulse wave signal and the second pulse wave signal, for example: the system may calculate the first pulse wave signal and the second pulse wave signal The signal quality of the signal, and then calculate the weights of the first pulse wave signal and the second pulse wave signal according to the above signal quality, and a higher weight can be set for the pulse wave signal with higher signal quality weight.

Through the above method, if the signal quality of a pulse wave signal is poor, a lower weight is set for the pulse wave signal with poor signal quality, thereby reducing the influence of signal quality on the blood pressure measurement accuracy, even if the signal quality of a pulse wave signal is poor It has high blood pressure measurement accuracy.

In the blood pressure measurement method provided by an embodiment of the present disclosure, the first pulse wave signal generated by the first part of the user and the second pulse wave signal generated by the second part of the user can be obtained after applying pressure to the first part of the user, The weighted average calculation is performed on the first pulse wave signal and the second pulse wave signal to obtain the user's systolic blood pressure measurement value and diastolic blood pressure measurement value. In this way, two pulse wave signals can be obtained and weighted to calculate the user's blood pressure measurement value, which can reduce the influence of signal quality and improve the accuracy of blood pressure measurement.

This embodiment also provides another blood pressure measurement method, which is implemented on the basis of the above-mentioned embodiments, as shown in Figure 2, the flow chart of another blood pressure measurement method, the blood pressure measurement method in this embodiment includes the following step:

Step S202, apply pressure to the first part of the user through the first pulse wave detection module; detect the first pulse wave signal generated by the first part of the user through the first pulse wave detection module; detect the user's body pressure through the second pulse wave detection module The second pulse wave signal generated by the second part.

Optionally, the first pulse wave detection module and the second pulse wave detection module can be set on the same side arm of the user; the first part of the user can be the proximal artery of the user's arm; the second part of the user can be It is the arterial vessel at the distal end of the user's arm. For example: the first location may be the brachial artery or the radial artery of the user's arm; the second location of the user may include the location from the first location of the user to the fingertip of the user.

Optionally, the first pulse wave detection module may include an arm or wrist electronic sphygmomanometer based on the oscillometric method; the measurement method of the electronic sphygmomanometer may include inflation measurement or deflation measurement; the second pulse wave detection module may at least Can include one of the following: photoplethysmography, lidar, optical imager, piezoelectric sensor, or capacitive sensor. Therefore, the average weighted calculation can be performed by the processor of the electronic sphygmomanometer. For example, the weighted average calculation can be performed on the first pulse wave signal and the second pulse wave signal by the processor of the electronic sphygmomanometer to obtain the blood pressure measurement value of the user.

Optionally, the first pulse wave detection module and the second pulse wave detection module can be designed in one piece or separately. Taking the integrated design as an example, the user wears the cuff of the electronic sphygmomanometer (that is, the first pulse wave detection module), turns on the blood pressure measurement device, and the blood pressure measurement device receives the user's command to start the blood pressure measurement, and starts to collect the user's first pulse wave signal and the second pulse wave signal.

After the blood pressure measurement device receives the blood pressure measurement command, the user needs to press the pad of the finger on the same side on the second pulse wave detection module integrated with the electronic blood pressure monitor. At this time, if the blood pressure measurement device determines that there is real pulse wave information in the collected second pulse wave signal and exceeds the duration threshold, blood pressure measurement may be started. The duration threshold here may be a preset value, for example, 5 seconds. Otherwise, prompt the user to measure in the correct way.

Wherein, the pulse wave amplitude of the first pulse wave signal first decreases and then increases until it becomes stable with the pressure applied to the user.

In some possible implementations, the pulse wave amplitude of the second pulse wave signal changes from large to small over time until the blood vessel is blocked and develops into a stable process; in some possible implementations, the pulse of the second pulse wave signal The wave amplitude changes from a stable process after the blood vessel is blocked to a process of increasing from small to large over time.

Specifically, when the measurement method of the electronic sphygmomanometer is inflatable measurement, the main pulse wave amplitude and the dicrotic wave amplitude of the second pulse wave signal change from large to small over time until the user's arterial blood vessel is blocked and become stable. process; when the measurement method of the electronic sphygmomanometer is deflated measurement, the amplitude of the main pulse wave and the amplitude of the dicrotic wave of the second pulse wave signal are as follows: from a stable process after the user's arterial blood vessel is blocked to by The process of growing from small to large.

For example, referring to a schematic diagram of a first pulse wave signal and a second pulse wave signal shown in Figure 3, the first pulse wave signal and the second pulse wave signal are collected simultaneously, and the electronic sphygmomanometer in Figure 3 adopts an inflatable measurement , the second pulse wave signal is a PPG (Photoplethysmogram, photoplethysmogram) pulse wave signal. It can be seen that the pulse wave amplitude of the PPG pulse wave signal changes from large to small over time, and finally tends to be stable.

Step S204, performing weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user; wherein, the blood pressure measurement value includes a systolic blood pressure measurement value and a diastolic blood pressure measurement value.

Optionally, when the weighted average calculation is performed on the first pulse wave signal and the second pulse wave signal, first the features of the first pulse wave signal and the features of the second pulse wave signal can be obtained, wherein the features can include but not limited to: The starting time of the main wave, the peak time of the main wave, the amplitude of the main wave, the moment of the descending gorge, the peak time of the dicrotic wave, the amplitude of the dicrotic wave, and the end time of the dicrotic wave of each pulse wave in the pulse wave signal; based on the first pulse The characteristics of the wave signal and the characteristics of the second pulse wave signal perform weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user.

According to the characteristics of the first pulse wave signal and the characteristics of the second pulse wave signal, it is possible to determine the invalid pulse wave of the first pulse wave signal and the second pulse wave signal, and reconstruct the pulse wave of the first pulse wave signal and the second pulse wave signal missing information. Wherein, the method for determining the invalid pulse wave further includes: determining the invalid first pulse wave and the invalid second pulse wave in the first pulse wave signal and the second pulse wave signal based on the characteristics of the first pulse wave signal and the characteristics of the second pulse wave signal, respectively. Two pulse waves; delete invalid first pulse wave and invalid second pulse wave.

Wherein, the above-mentioned method for reconstructing the missing information can be performed through the following steps: If the main wave peak time signal of the second pulse wave signal is missing at the time when the first main wave peak time occurs in the first pulse wave signal, based on the first main wave peak The characteristics of multiple second pulse wave signals before and after the first occurrence moment reconstruct the characteristics of the missing pulse wave first occurrence moment corresponding to the first main wave peak moment of the second pulse wave signal; if the second pulse wave signal The main wave peak time signal of the first pulse wave is missing at the second occurrence time of the second main wave peak time, and the first pulse wave signal is reconstructed based on the characteristics of a plurality of first pulse wave signals before and after the second main wave peak time at the second occurrence time time The characteristics of the missing pulse wave second occurrence moment corresponding to the second main wave peak moment of the wave signal.

Wherein, the first pulse wave signal refers to a sequence composed of pulse waves, such as pulse wave 1, pulse wave 2, pulse wave 3...

The first pulse wave signal needs to delete the invalid pulse wave first, and reconstruct the missing pulse wave; the reference basis for deletion can include the amplitude, convexity, width, rise and fall time and other characteristics of any pulse wave Whether it is within 3 times the interquartile range of all characteristics.

The method of judging the effectiveness of any pulse wave can refer to but not limited to the following formula:

QL-1.5×IQR≤F≤QU+1.5×IQR;

Among them, F is the selected feature of the pulse wave, such as the peak amplitude of the main wave, QL and QU are the lower and upper quartiles of the distribution formed by the same type of features of all pulse waves, and IQR is the interquartile range. Further, it may refer to whether multiple features satisfy the above formula at the same time.

The reference basis for the absence may be whether there is no pressure pulse wave at the moment corresponding to the non-invalid second pulse wave. If it is determined to be missing, you can refer to but not limited to the following formula to reconstruct the characteristics corresponding to the first pulse wave, taking the reconstruction of the amplitude A(t) at time t as an example:

_Δi = A(i)-A(i-1);

Among them, w _i is the weight of the pulse wave amplitude variation at time i.

Similarly, it is also necessary to delete the invalid pulse wave and reconstruct the missing pulse wave for the second pulse wave signal; the basis for deletion may include the main peak amplitude of any pulse wave, the duration of the descending gorge from the starting point of the pulse wave, the Whether the time length from the gorge to the end point of the pulse wave, the amplitude of the dicrotic wave and other features are within 3 times the interquartile range of all features. The basis for missing can be whether the second pulse wave is missing at the time corresponding to the non-invalid first pulse wave. If the missing is determined, the second pulse wave feature can be reconstructed by referring to the reconstruction method in the first pulse wave.

After deleting the invalid pulse wave and reconstructing the missing pulse wave for the first pulse wave and the second pulse wave, the signal quality of the pulse wave can be calculated according to the invalid pulse wave, for example: statistical invalid first pulse wave in the first pulse wave signal The first proportion of the first proportion and the second proportion of the invalid second pulse wave in the second pulse wave signal; the signal quality of the first pulse wave is calculated based on the characteristics of the first pulse wave signal and the first proportion; based on the second pulse wave The signal quality of the second pulse wave is calculated according to the characteristic of the wave signal and the second proportion.

The above ratio refers to the ratio of the number of invalid pulse waves to the total number of pulse waves. Wherein, the first pulse wave signal after this step refers to the signal after the invalid first pulse wave is deleted, and the second pulse wave signal refers to the signal after the invalid second pulse wave is deleted. To determine the signal quality of the first pulse wave signal or the second pulse wave signal, you can refer to but not limited to the following formula:

ω=Q×CV _F ;

Among them, Q is the invalid proportion, CV _F is the coefficient of variation of selected features such as the peak time of the main wave, (F _i+1 -F _i ) is the interval between adjacent main wave peak times, and w represents the The interval time between peak moments is used as the reference signal quality. Further, the average value of w calculated with reference to multiple features may be used.

Or, based on a machine learning model such as a decision tree, the proportion of invalid pulse waves and the coefficient of variation of different features are constructed as feature vectors to output signal quality in a statistical sense. In this way, human experts are required to pre-mark the signal quality of the first pulse wave signal and the second pulse wave signal, and construct the first pulse wave signal quality judgment model and the second pulse wave signal quality judgment model according to the assigned marks. Signal quality judgment model.

After acquiring the features of the first pulse wave signal and the features of the second pulse wave signal, the user's blood pressure measurement value can be calculated in the following manner: based on the features of the first pulse wave signal, the user's average blood pressure is determined by using the variable amplitude coefficient method. The measured value MAP, the first systolic blood pressure measured value SBP ₁ and the first diastolic blood pressure measured value DBP ₁ ; based on the characteristics of the second pulse wave signal, the initial moment of the stabilization process when the inflation type measurement is performed or when the deflation type measurement The pressure corresponding to the end moment of the stabilization process is taken as the second systolic blood pressure measurement value SBP ₂ ; the characteristics of the second pulse wave signal and the average pressure measurement value MAP are input into the preset second diastolic pressure model, and the second diastolic pressure measurement value is output value DBP ₂ ; weighted average calculation is performed on the first systolic blood pressure measurement value SBP ₁ and the second systolic blood pressure measurement value SBP ₂ to obtain the user's systolic blood pressure measurement value SBP; for the first diastolic blood pressure measurement value DBP ₁ and the second diastolic blood pressure measurement value The measured value DBP ₂ performs weighted average calculation to obtain the user's diastolic blood pressure measured value DBP.

The mean pressure MAP of the first pulse wave signal, the first systolic blood pressure SBP ₁ and the first diastolic blood pressure DBP ₁ can be obtained by using the coefficient of variation method. However, the amplitude coefficient usually needs to be adapted to the hardware limitations of different electronic sphygmomanometers, such as the width, material, and length of the cuff.

The calculation of the second systolic blood pressure SBP ₂ of the second pulse wave signal can be referred to FIG. 3 , and the initial moment after the pulse wave amplitude of the second pulse wave signal tends to stabilize is selected, that is, point A in FIG. 3( a ). After that point, no change in amplitude occurs. For the determination that the amplitude no longer changes, reference may be made, but not limited to, that all four adjacent amplitudes are less than or equal to 0.1 times of all previous amplitudes.

The calculation of the second diastolic pressure DBP ₂ of the second pulse wave signal adopts the following formula:

DBP ₂ =(MAP-a×SBP ₂ )/b;

Among them, t _s (i) is the duration from the starting moment of the main wave of the i-th pulse wave to the moment of descending the middle gorge, which generally indicates the duration of the systolic period, that is, point A (starting moment of the main wave) in Figure 3(b) to The duration of point C (Jiangzhongxia moment). t _d (i) is the duration from the moment of descending middle gorge of the i-th pulse wave to the end of dicrotic wave, which generally indicates the duration of the diastolic period, that is, point C (moment of descending middle gorge) to point E (central gorge) in Figure 3(b). The duration of the wave at the end of the wave). N is the number of pulse waves in the second pulse wave signal.

When performing weighted average calculation, it is necessary to determine the weight of the weighted average calculation. There are two ways, one is to preset the weight in advance, for example: based on the preset first weight value and second weight value to measure the first systolic blood pressure The weighted average calculation of the measured systolic blood pressure and the second measured systolic blood pressure is performed to obtain the measured systolic blood pressure of the user; the first diastolic blood pressure measured value and the second diastolic blood pressure measured value are weighted based on the preset third weight value and fourth weight value Calculate the average to get the user's diastolic blood pressure measurement.

Optionally, the first weight value, the second weight value, the third weight value and the fourth weight value may be the same or different, which is not limited here. The above method can perform weighted average calculation according to preset weights, and the calculation speed is fast and the efficiency is high.

The other is to calculate the weight of the first pulse wave signal and the weight of the second pulse wave signal according to the above signal quality after determining the signal quality of the first pulse wave and the signal quality of the second pulse wave, for example: based on the first pulse wave The signal quality of the pulse wave and the signal quality of the second pulse wave determine the weight of the first pulse wave signal and the weight of the second pulse wave signal; The measured value and the second systolic blood pressure measured value are weighted and averaged to obtain the user's systolic blood pressure measured value; the first diastolic blood pressure measured value and the second diastolic blood pressure are calculated by the weight of the first pulse wave signal and the weight of the second pulse wave signal The measured values are weighted and averaged to obtain the measured value of the user's diastolic blood pressure.

Wherein, if it is confirmed that the first pulse wave signal or the second pulse wave signal does not meet the preset signal quality, the user is reminded that the measurement failed; if it is confirmed that the difference between the first systolic blood pressure and the second systolic blood pressure exceeds the preset difference threshold, if the first If the difference between the systolic blood pressure and the second systolic blood pressure exceeds the preset difference threshold, the first systolic blood pressure is directly used as the user's systolic blood pressure measurement; if the difference between the first diastolic blood pressure and the second diastolic pressure exceeds the preset difference threshold, the Use the first diastolic pressure as the user's systolic blood pressure measurement; if it is confirmed that the difference between the first diastolic pressure and the second diastolic pressure exceeds a preset difference threshold, directly select the one with better signal quality as the weighted average output.

For example: if the signal quality of the first pulse wave is less than the preset first threshold, the weight of the first pulse wave signal is 0, and the weight of the second pulse wave signal is 1; if the signal quality of the second pulse wave is less than the preset The second threshold, the weight of the second pulse wave signal is 0, and the weight of the first pulse wave signal is 1; if the difference between the signal quality of the first pulse wave and the signal quality of the second pulse wave is greater than the preset threshold, the first The pulse wave has a weight of 1 and the second pulse wave has a weight of 0.

The weighted average of the systolic blood pressure SBP measured by the user can be calculated as follows, but not limited to: SBP=w ₁ ×SBP ₁ +w ₂ ×SBP ₂ ; w ₁ +w ₂ =1; where, the weights w ₁ and w ₂ can be directly set by preset can also be adjusted in real time through signal quality.

It should be noted that the weighted average can only be used when the difference between SBP ₁ and SBP ₂ is within the preset difference threshold range. In this embodiment, the difference threshold can be set to 15 mmHg. If the difference threshold is exceeded, the first systolic blood pressure can be directly used as the SBP.

Users can refer to the process of SBP for measuring the weighted average of diastolic blood pressure DBP. The weights w3 and w4 can be directly obtained by preset or adjusted in real time by signal quality, for example: DBP=w ₃ ×DBP ₁ +w ₄ ×DBP ₂ .

In another scenario, the method of measuring blood pressure by fusing the first pulse wave signal and the second pulse wave signal may not be able to perform mutual compensation because the first pulse wave and the second pulse wave have invalid pulse waves or missing pulse waves at the same time . For example, slight jitter during user measurement, weak perfusion accompanied by insufficient cuff pressure and other phenomena. Optionally, other physiological signals collected synchronously can be added. Optionally, the other physiological signal is a third signal or more signals, and the type of the signal may overlap with the second pulse wave signal.

For example: obtaining other physiological signals of the user; reconstructing the features of the missing first pulse wave signal and the missing second pulse wave signal through other physiological signals; compensating the user's blood pressure measurement value through other physiological signals, The compensated blood pressure measurement of the user.

Specifically, the above-mentioned other physiological signals include at least one of the following: electrocardiogram signals, photoplethysmography signals, lidar signals, optical imaging signals, piezoelectric sensor signals or capacitive sensor signals.

For example, the other physiological signal may be an ECG (Electrocardiogram, electrocardiogram) signal or a PPG pulse wave signal at other locations. The ECG signal or PPG pulse wave signal from other parts can not only be used to further judge the invalid pulse wave or missing pulse wave, but also can calculate the pulse wave transit time (PulseWaveTransitTime, PWTT) with the existing second pulse wave signal, etc. parameter. The newly added parameters can be further incorporated into the calculation of DBP and SBP.

For example, referring to the schematic diagram of a blood pressure measurement method shown in FIG. 4, the blood pressure can be measured in the following manner:

Because the user first puts his finger on the first pulse wave detection module, it is relatively easy to acquire the second pulse wave. Therefore, the user can start the blood pressure measurement first, and collect the second pulse wave signal at the same time. If it is confirmed that the real second pulse wave is not detected, it will prompt the correct measurement. If it is confirmed that the real second pulse wave is detected, the first pulse wave signal and the second pulse wave signal are collected.

The invalid first pulse wave is deleted, the missing first pulse wave is reconstructed, and the signal quality of the first pulse wave is calculated. The invalid second pulse wave is deleted, the missing second pulse wave is reconstructed, and the signal quality of the second pulse wave is calculated. Calculate the first systolic and first diastolic, and calculate the second systolic and second diastolic.

If it is confirmed that neither the first pulse wave signal quality nor the second signal quality meets the signal quality condition, the user is prompted that the measurement fails. Calculate the difference between the first systolic blood pressure and the second systolic blood pressure, the difference between the second systolic blood pressure and the second diastolic blood pressure; the weighted average of the first and second systolic blood pressure, if there is a pulse wave signal quality that does not meet the signal quality conditions, adjust the weighted weight to Zero, only output the systolic and diastolic blood pressure corresponding to one pulse wave signal that meets the signal quality conditions.

Referring to the schematic diagram of a blood pressure measuring device shown in FIG. 5, the first pulse wave detection module 31 and the second pulse wave detection module 36 are discrete, wherein the first pulse wave detection module 31 is separated from the cuff 35 and the host Type electronic sphygmomanometer, the second pulse wave detection module 36 is a smart watch or smart bracelet separated from the first pulse wave detection module 31. Specifically, it also includes a display screen 32 , user buttons 33 , an air circuit 34 , a micro laser source 37 and a photodiode 38 .

Referring to the schematic diagram of another blood pressure measuring device shown in FIG. 6, the second pulse wave signal is collected by a separate second pulse wave detection module 46, and optionally sent to the first pulse wave detection module 41 via Bluetooth connection for further processing. deal with.

Referring to the schematic diagram of another blood pressure measuring device shown in FIG. 7, another optional implementation of the integration of the first pulse wave detection module 49 and the second pulse wave detection module 55, wherein the first pulse wave detection module 49 is For an electronic sphygmomanometer integrated with the cuff 52 and the host, the second pulse wave detection module 55 is located at the edge of the cuff 52 close to the user's palm. Specifically, it also includes a display screen 50 , user buttons 51 , a micro laser source 53 and a photodiode 54 .

To sum up, the above-mentioned method provided by the embodiments of the present disclosure, which integrates multiple pulse wave information, has a blood pressure measurement result that is more accurate than a single information; the blood pressure measurement method is applied to a blood pressure measurement device, and the method includes: obtaining The blood pressure multimodal signal, the blood pressure multimodal signal includes the first pulse wave signal generated by the pressure acting on the first part of the user, and the second pulse wave signal generated by the second part of the user when the pressure acts on the user; Invalid and missing information of the first pulse wave signal and the second pulse wave signal, and implement mutual compensation; obtain the signal quality respectively for the first pulse wave signal and the second pulse wave signal; calculate the average pressure, the first pulse wave signal according to the first pulse wave signal systolic blood pressure and first diastolic blood pressure, and calculate the second systolic blood pressure and second diastolic blood pressure according to the second pulse wave signal; according to the quality of the first pulse wave signal and the second pulse wave signal quality, the The user's systolic blood pressure measurement is obtained by fusion, and the user's diastolic blood pressure measurement is obtained by fusion of the first diastolic pressure and the second diastolic pressure.

The above method provided by the embodiments of the present disclosure can improve the accuracy of blood pressure measurement, and even if the first pulse wave signal or the second pulse wave signal has a signal quality defect, the user's blood pressure measurement value can be obtained more accurately.

Corresponding to the above method embodiment, the embodiment of the present disclosure also provides a blood pressure measurement device, refer to the schematic structural diagram of a blood pressure measurement device shown in FIG. 8 , the blood pressure measurement device includes:

The multimodal information acquisition module 81 is configured to apply pressure to the first part of the user to obtain the multimodal information of the user's blood pressure; wherein the multimodal information of the blood pressure includes the first pulse generated by the first part of the user wave signal and the second pulse wave signal generated by the second part of the user;

The weighted average calculation module 82 is configured to perform weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user; wherein, the blood pressure measurement value includes a systolic blood pressure measurement value and a diastolic blood pressure measurement value .

An embodiment of the present disclosure provides a blood pressure measurement device, which can obtain a first pulse wave signal generated by the first part of the user and a second pulse wave signal generated by the second part of the user after applying pressure to the first part of the user, The weighted average calculation is performed on the first pulse wave signal and the second pulse wave signal to obtain the user's systolic blood pressure measurement value and diastolic blood pressure measurement value. In this way, two pulse wave signals can be obtained and weighted to calculate the user's blood pressure measurement value, which can reduce the influence of signal quality and improve the accuracy of blood pressure measurement.

The above-mentioned multimodal information acquisition module is configured to apply pressure to the first part of the user through the first pulse wave detection module; detect the first pulse wave signal generated by the first part of the user through the first pulse wave detection module; The second pulse wave signal generated by the second part of the user is detected by the second pulse wave detection module.

The above-mentioned first pulse wave detection module and the second pulse wave detection module are set on the same side arm of the user; the first part of the user is the proximal end artery of the user's arm; the second part of the user is the distal end of the user's arm. Cardiac arteries.

The above-mentioned first pulse wave detection module includes an arm-type or wrist-type electronic sphygmomanometer based on the oscillometric method; the second pulse wave detection module includes at least one of the following: photoplethysmography, laser radar, optical imager, piezoelectric Sensor or capacitive sensor; the above weighted average calculation module is configured to perform weighted average calculation on the first pulse wave signal and the second pulse wave signal by the processor of the electronic sphygmomanometer to obtain the blood pressure measurement value of the user.

The measurement methods of the electronic sphygmomanometer include inflation measurement and deflation measurement; when the measurement method of the electronic sphygmomanometer is inflation measurement, the pulse wave main wave amplitude and dicrotic wave amplitude of the second pulse wave signal change from large to small over time , until the user's arterial blood vessel is blocked, it evolves into a stable process; when the electronic sphygmomanometer measures deflation, the pulse wave main wave amplitude and dicrotic wave amplitude of the second pulse wave signal are: determined by the user's arterial The stable process after the blood vessel is blocked evolves from small to large over time.

The above-mentioned weighted average calculation module is configured to obtain the features of the first pulse wave signal and the features of the second pulse wave signal; wherein, the features may at least include: the starting moment of each main wave in the pulse wave signal, Main wave peak time, main wave amplitude, descending gorge time, dicrotic wave peak time, dicrotic wave amplitude, dicrotic wave end time; based on the characteristics of the first pulse wave signal and the characteristics of the second pulse wave signal The weighted average calculation is performed on the pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user.

The above-mentioned weighted average calculation module is configured to determine the average blood pressure measurement value, the first systolic blood pressure measurement value and the first diastolic blood pressure measurement value of the user based on the characteristics of the first pulse wave signal by using the variable amplitude coefficient method; The characteristics of the pulse wave signal, the pressure corresponding to the initial moment of the stable process during the inflatable measurement or the end moment of the stable process during the deflated measurement is used as the second systolic blood pressure measurement value; the characteristic of the second pulse wave signal The characteristics of the first pulse wave signal corresponding to the average pressure measurement value are input into the preset human blood vessel elastic cavity model, and the second diastolic pressure measurement value is output; weighted average is performed on the first systolic pressure measurement value and the second systolic pressure measurement value Calculate to obtain the measured systolic blood pressure of the user; perform weighted average calculation on the first measured diastolic blood pressure and the second measured diastolic blood pressure to obtain the measured diastolic blood pressure of the user.

The above-mentioned weighted average calculation module is configured to perform weighted average calculation on the first systolic blood pressure measurement value and the second systolic blood pressure measurement value based on the preset first weight value and second weight value to obtain the user's systolic blood pressure measurement value ; Based on the preset third weight value and the fourth weight value, the weighted average calculation is performed on the first diastolic blood pressure measurement value and the second diastolic blood pressure measurement value to obtain the diastolic blood pressure measurement value of the user.

The above-mentioned weighted average calculation module is further configured to determine the invalid first pulse wave and the invalid The second pulse wave; delete the invalid first pulse wave and the invalid second pulse wave; count the first proportion of the invalid first pulse wave in the first pulse wave signal and the proportion of the invalid second pulse wave in the second pulse wave signal The second proportion; calculate the signal quality of the first pulse wave based on the characteristics of the first pulse wave signal and the first proportion; calculate the signal quality of the second pulse wave based on the characteristics of the second pulse wave signal and the second proportion; The signal quality of the first pulse wave and the signal quality of the second pulse wave determine the weight of the first pulse wave signal and the weight of the second pulse wave signal; the above-mentioned weighted average calculation module is configured to use the weight of the first pulse wave signal The weight and the weight of the second pulse wave signal perform a weighted average calculation on the first systolic blood pressure measurement value and the second systolic blood pressure measurement value to obtain the user's systolic blood pressure measurement value; the above weighted average calculation module is configured to use the first The weight of the pulse wave signal and the weight of the second pulse wave signal perform weighted average calculation on the first measured value of diastolic pressure and the second measured value of diastolic pressure to obtain the measured value of the user's diastolic pressure.

The above-mentioned weighted average calculation module is configured to if the signal quality of the first pulse wave is less than the preset first threshold, the weight of the first pulse wave signal is 0, and the weight of the second pulse wave signal is 1; if the second The signal quality of the pulse wave is less than the preset second threshold, the weight of the second pulse wave signal is 0, and the weight of the first pulse wave signal is 1; if the signal quality of the first pulse wave is equal to the signal quality of the second pulse wave If the difference is greater than the preset threshold, the weight of the first pulse wave is 1, and the weight of the second pulse wave is 0.

The above-mentioned weighted average calculation module is configured to, if the main wave peak time of the second pulse wave is missing at the first main wave peak time of the first pulse wave signal, based on a plurality of second pulses before and after the first main wave peak time The feature of the wave signal reconstructs the feature of the missing pulse wave corresponding to the first main wave peak moment of the second pulse wave signal; if the main wave peak of the first pulse wave is missing at the second main wave peak moment of the second pulse wave signal time, based on the features of the multiple first pulse wave signals before and after the peak time of the second main wave, the features of the missing pulse wave corresponding to the peak time of the second main wave of the first pulse wave signal are reconstructed.

The above-mentioned weighted average calculation module is also configured to obtain other physiological signals of the user; the above-mentioned other physiological signals include at least one of the following: electrocardiogram signal, photoplethysmography signal, laser radar signal, optical imaging signal, piezoelectric sensor signal or capacitive sensor signal; reconstruct the feature of the missing first pulse wave signal and the feature of the missing second pulse wave signal through other physiological signals; the above-mentioned weighted average calculation module is also configured to use other physiological signals The physiological signal compensates the user's blood pressure measurement value, and obtains the user's blood pressure measurement value after compensation.

Those skilled in the art can clearly understand that for the convenience and brevity of description, the specific working process of the blood pressure measuring device described above can refer to the corresponding process in the embodiment of the aforementioned blood pressure measuring method, which will not be repeated here.

An embodiment of the present disclosure also provides an electronic device for running the above blood pressure measurement method; refer to the schematic structural diagram of an electronic device shown in FIG. One or more computer instructions are stored, and one or more computer instructions are executed by the processor 101 to implement the above blood pressure measurement method.

Optionally, the electronic device shown in FIG. 9 further includes a bus 102 and a communication interface 103 , and the processor 101 , the communication interface 103 and the memory 100 are connected through the bus 102 .

Wherein, the memory 100 may include a high-speed random access memory (RAM, Random Access Memory), and may also include a non-volatile memory (non-volatile memory), such as at least one disk memory. The communication connection between the system network element and at least one other network element is realized through at least one communication interface 103 (which may be wired or wireless), and the Internet, wide area network, local network, metropolitan area network, etc. can be used. The bus 102 may be an ISA bus, a PCI bus, or an EISA bus, etc. The bus can be divided into address bus, data bus, control bus and so on. For ease of representation, only one double-headed arrow is used in FIG. 9 , but it does not mean that there is only one bus or one type of bus.

The processor 101 may be an integrated circuit chip with signal processing capability. In the implementation process, each step of the above method can be completed by an integrated logic circuit of hardware in the processor 101 or instructions in the form of software. Above-mentioned processor 101 can be general-purpose processor, comprises central processing unit (Central Processing Unit, be called for short CPU), network processor (Network Processor, be called for short NP) etc.; Can also be digital signal processor (Digital Signal Processor, be called for short DSP), ASIC (Application Specific Integrated Circuit, referred to as ASIC), Field-Programmable Gate Array (Field-Programmable Gate Array, referred to as FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components. Various methods, steps and logic block diagrams disclosed in the embodiments of the present disclosure may be implemented or executed. A general-purpose processor may be a microprocessor, or the processor may be any conventional processor, or the like. The steps of the methods disclosed in the embodiments of the present disclosure may be directly implemented by a hardware decoding processor, or implemented by a combination of hardware and software modules in the decoding processor. The software module can be located in a mature storage medium in the field such as random access memory, flash memory, read-only memory, programmable read-only memory or electrically erasable programmable memory, register. The storage medium is located in the memory 100, and the processor 101 reads the information in the memory 100, and completes the steps of the methods in the foregoing embodiments in combination with its hardware.

An embodiment of the present disclosure also provides a computer-readable storage medium, the computer-readable storage medium stores computer-executable instructions, and when the computer-executable instructions are invoked and executed by a processor, the computer-executable instructions cause the processor to implement For the specific implementation of the above blood pressure measurement method, refer to the method embodiments, which will not be repeated here.

The computer program product of the blood pressure measurement method, device, and electronic equipment provided by the embodiments of the present disclosure includes a computer-readable storage medium storing program codes, and the instructions contained in the program codes can be used to execute the methods in the previous method embodiments, and the specific implementation Reference may be made to the method embodiments, and details are not repeated here.

Those skilled in the art can clearly understand that for the convenience and brevity of description, the specific working process of the system and/or device described above can refer to the corresponding process in the foregoing method embodiment, and details are not repeated here.

In addition, in the description of the embodiments of the present disclosure, unless otherwise specified and limited, the terms "installation", "connection" and "connection" should be interpreted in a broad sense, for example, it can be a fixed connection or a detachable connection , or integrally connected; it may be mechanically connected or electrically connected; it may be directly connected or indirectly connected through an intermediary, and it may be the internal communication of two components. Those of ordinary skill in the art can understand the specific meanings of the above terms in the present disclosure in specific situations.

If the functions described above are realized in the form of software function units and sold or used as independent products, they can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of the present disclosure is essentially or the part that contributes to the prior art or the part of the technical solution can be embodied in the form of a software product, and the computer software product is stored in a storage medium, including Several instructions are used to make a computer device (which may be a personal computer, a server, or a network device, etc.) execute all or part of the steps of the methods described in various embodiments of the present disclosure. The aforementioned storage medium includes: U disk, mobile hard disk, read-only memory (ROM, Read-OnlyMemory), random access memory (RAM, RandomAccessMemory), magnetic disk or optical disk and other media that can store program codes.

In the description of the present disclosure, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" etc. The indicated orientations or positional relationships are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present disclosure and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation or be in a specific orientation. construction and operation are therefore not to be construed as limitations on the present disclosure. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and should not be construed as indicating or implying relative importance.

Finally, it should be noted that: the above-mentioned embodiments are only specific implementations of the present disclosure, and are used to illustrate the technical solutions of the present disclosure, rather than limit them, and the protection scope of the present disclosure is not limited thereto, although referring to the aforementioned The embodiments have described the present disclosure in detail, and those skilled in the art should understand that any person familiar with the technical field can still modify the technical solutions described in the foregoing embodiments within the technical scope disclosed in the present disclosure Changes can be easily imagined, or equivalent replacements can be made to some of the technical features; and these modifications, changes or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present disclosure, and should be included in this disclosure. within the scope of protection. Therefore, the protection scope of the present disclosure should be defined by the protection scope of the claims.

Industrial Applicability

The present disclosure provides a blood pressure measurement method, device and electronic equipment, which can obtain the first pulse wave signal generated by the user's first part and the second pulse wave signal generated by the user's second part after the pressure is applied to the user's first part signal, performing weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the user's systolic blood pressure measurement value and diastolic blood pressure measurement value. In this way, two pulse wave signals can be obtained and weighted to calculate the user's blood pressure measurement value, which can reduce the influence of signal quality and improve the accuracy of blood pressure measurement.

Furthermore, it is understood that the blood pressure measurement method, apparatus and electronic equipment of the present disclosure are reproducible and can be used in various industrial applications. For example, the blood pressure measuring method, device and electronic equipment disclosed in the present disclosure can be used in the field of medical technology.

Claims

A method for measuring blood pressure, characterized in that the method comprises:

applying pressure to the first part of the user to obtain multimodal blood pressure information of the user; wherein the multimodal blood pressure information includes the first pulse wave signal generated by the first part of the user and the user's the second pulse wave signal generated by the second part;

A weighted average calculation is performed on the first pulse wave signal and the second pulse wave signal to obtain a blood pressure measurement value of the user; wherein the blood pressure measurement value includes a systolic blood pressure measurement value and a diastolic blood pressure measurement value.
The method according to claim 1, wherein the step of applying pressure to the first part of the user and obtaining the multimodal information of the user's blood pressure comprises:

applying pressure to the first part of the user through the first pulse wave detection module;

Detecting the first pulse wave signal generated by the first part of the user through the first pulse wave detection module;

The second pulse wave signal generated by the second part of the user is detected by the second pulse wave detection module.
The method according to claim 2, wherein the first pulse wave detection module and the second pulse wave detection module are arranged on the same side arm of the user; the first part of the user is the The proximal artery of the user's arm; the second location of the user is the distal artery of the user's arm.
The method according to claim 2 or 3, wherein the first pulse wave detection module includes an oscillometric arm or wrist electronic sphygmomanometer; the second pulse wave detection module includes at least one of the following One: photoplethysmography, lidar, optical imager, piezoelectric sensor or capacitive sensor;

The step of performing weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user includes:

The processor of the electronic sphygmomanometer performs weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user.
The method according to claim 4, characterized in that the measurement methods of the electronic sphygmomanometer include inflation measurement and deflation measurement;

When the measurement method of the electronic sphygmomanometer is the inflation type measurement, the main pulse wave amplitude and the dicrotic wave amplitude of the second pulse wave signal change from large to small over time until the user's arterial blood vessel is blocked. Evolves into a stable process after breaking;

When the measurement method of the electronic sphygmomanometer is the deflation type measurement, the pulse wave main wave amplitude and the dicrotic wave amplitude of the second pulse wave signal are: the stable pulse wave amplitude after the user's arterial blood vessel is blocked A process evolves from small to large over time.
The method according to any one of claims 1 to 5, characterized in that, the step of performing weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user ,include:

Obtaining the features of the first pulse wave signal and the features of the second pulse wave signal; wherein, the features at least include: the start time of the main wave, the peak time of the main wave, and the main wave of each pulse wave in the pulse wave signal. Amplitude of wave, time of descending middle gorge, peak moment of dicrotic wave, amplitude of dicrotic wave, end time of dicrotic wave;

Based on the features of the first pulse wave signal and the features of the second pulse wave signal, weighted average calculation is performed on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user.
The method according to claim 6, wherein the first pulse wave signal and the second pulse wave signal are performed based on the characteristics of the first pulse wave signal and the characteristics of the second pulse wave signal. Weighted average calculation to obtain the blood pressure measurement value of the user, including:

Based on the characteristics of the first pulse wave signal, the user's average blood pressure measurement value MAP, the first systolic blood pressure measurement value SBP1 and the first diastolic blood pressure measurement value DBP1 are determined by using the variable amplitude coefficient method;

Based on the characteristics of the second pulse wave signal, the pressure corresponding to the start moment of the stabilization process during inflation-type measurement or the end moment of the stabilization process during deflation-type measurement is taken as the second systolic blood pressure measurement value SBP 2 ;

Inputting the characteristics of the second pulse wave signal and the measured mean pressure value MAP into a preset second diastolic pressure model, and outputting a second measured value DBP 2 of diastolic pressure;

performing weighted average calculation on the first measured systolic blood pressure SBP 1 and the second measured systolic blood pressure SBP 2 to obtain the measured systolic blood pressure SBP of the user;

A weighted average calculation is performed on the first measured diastolic blood pressure DBP1 and the second measured diastolic blood pressure DBP2 to obtain the user's diastolic blood pressure measured DBP.
The method according to claim 7, wherein the weighted average calculation is performed on the first measured systolic blood pressure SBP 1 and the second measured systolic blood pressure SBP 2 to obtain the measured systolic blood pressure SBP of the user ,include:

Perform weighted average calculation on the first systolic blood pressure measurement value SBP 1 and the second systolic blood pressure measurement value SBP 2 based on the preset first weight value and second weight value to obtain the systolic blood pressure measurement value SBP of the user ;

The step of performing weighted average calculation on the first diastolic blood pressure measurement value DBP 1 and the second diastolic blood pressure measurement value DBP 2 to obtain the user's diastolic blood pressure measurement value DBP includes:

Perform weighted average calculation on the first diastolic blood pressure measurement value DBP 1 and the second diastolic blood pressure measurement value DBP 2 based on the preset third weight value and fourth weight value to obtain the user's diastolic blood pressure measurement value DBP .
The method according to claim 7, wherein the method further comprises:

Determining an invalid first pulse wave and an invalid second pulse wave in the first pulse wave signal and the second pulse wave signal based on the characteristics of the first pulse wave signal and the characteristics of the second pulse wave signal, respectively ;

deleting the invalid first pulse wave and the invalid second pulse wave;

counting the first proportion of the invalid first pulse wave in the first pulse wave signal and the second proportion of the invalid second pulse wave in the second pulse wave signal;

calculating the signal quality of the first pulse wave based on the characteristics of the first pulse wave signal and the first ratio;

calculating the signal quality of the second pulse wave based on the characteristics of the second pulse wave signal and the second proportion;

determining the weight of the first pulse wave signal and the weight of the second pulse wave signal based on the signal quality of the first pulse wave and the signal quality of the second pulse wave;

The step of performing weighted average calculation on the first measured systolic blood pressure SBP 1 and the second measured systolic blood pressure SBP 2 to obtain the measured systolic blood pressure SBP of the user includes:

The weighted average calculation of the first systolic blood pressure measurement value SBP1 and the second systolic blood pressure measurement value SBP2 is performed by using the weight of the first pulse wave signal and the weight of the second pulse wave signal to obtain the User's systolic blood pressure measurement SBP;

The step of performing weighted average calculation on the first diastolic blood pressure measurement value DBP 1 and the second diastolic blood pressure measurement value DBP 2 to obtain the user's diastolic blood pressure measurement value DBP includes:

Perform weighted average calculation on the first diastolic blood pressure measurement value and the second diastolic blood pressure measurement value by using the weight of the first pulse wave signal and the weight of the second pulse wave signal to obtain the diastolic blood pressure of the user Measurements.
The method according to claim 9, wherein the weight of the first pulse wave signal and the weight of the second pulse wave signal are determined based on the signal quality of the first pulse wave and the signal quality of the second pulse wave. The steps of signal weighting include:

If the signal quality of the first pulse wave is less than the preset first threshold, the weight of the first pulse wave signal is 0, and the weight of the second pulse wave signal is 1;

If the signal quality of the second pulse wave is less than the preset second threshold, the weight of the second pulse wave signal is 0, and the weight of the first pulse wave signal is 1;

If the difference between the signal quality of the first pulse wave and the signal quality of the second pulse wave is greater than a preset threshold, the weight of the first pulse wave is 1, and the weight of the second pulse wave is 0.
The method according to any one of claims 6 to 10, further comprising:

If the main wave peak time of the second pulse wave signal is missing at the first main wave peak time of the first pulse wave signal, based on the feature re- Constructing the characteristics of the missing pulse wave corresponding to the peak moment of the first main wave of the second pulse wave signal;

If the main wave peak time of the first pulse wave signal is missing at the second main wave peak time of the second pulse wave signal, based on the feature re- The feature of the missing pulse wave corresponding to the peak moment of the second main wave of the first pulse wave signal is constructed.
The method according to any one of claims 6 to 11, wherein after the step of applying pressure to the first part of the user, the method further comprises:

Acquiring other physiological signals of the user, the other physiological signals include at least one of the following: electrocardiogram signal, photoplethysmography signal, lidar signal, optical imaging signal, piezoelectric sensor signal or capacitive sensor signal;

reconstructing the missing features of the first pulse wave signal and the missing features of the second pulse wave signal from the other physiological signals;

After the step of obtaining the blood pressure measurement value of the user, the method further includes:

The blood pressure measurement value of the user is compensated by using the other physiological signals, and the compensated blood pressure measurement value of the user is obtained.
A blood pressure measuring device, characterized in that the device comprises:

The multimodal information acquisition module is configured to apply pressure to the first part of the user to obtain multimodal blood pressure information of the user; wherein the multimodal information of blood pressure includes the first part of the user a first pulse wave signal generated and a second pulse wave signal generated by a second part of the user;

The weighted average calculation module is configured to perform weighted average calculation on the first pulse wave signal and the second pulse wave signal to obtain the blood pressure measurement value of the user; wherein the blood pressure measurement value includes systolic blood pressure measurements and diastolic measurements.
The blood pressure measurement device according to claim 13, wherein the multimodal information acquisition module is configured to apply pressure to the user's first part through the first pulse wave detection module; A pulse wave detection module detects a first pulse wave signal generated by a first part of the user; a second pulse wave signal generated by a second part of the user is detected by a second pulse wave detection module.
The blood pressure measuring device according to claim 14, wherein the first pulse wave detection module and the second pulse wave detection module are arranged on the same side arm of the user; The arterial vessel at the proximal end of the arm of the user; the second location of the user is the arterial vessel at the distal end of the arm of the user.
The blood pressure measuring device according to claim 14 or 15, wherein the first pulse wave detection module includes an oscillometric arm or wrist electronic sphygmomanometer; the second pulse wave detection module at least includes One of the following: photoplethysmography, lidar, optical imager, piezoelectric sensor, or capacitive sensor;

The weighted average calculation module is configured to perform weighted average calculation on the first pulse wave signal and the second pulse wave signal by the processor of the electronic sphygmomanometer to obtain the blood pressure measurement value of the user.
The blood pressure measuring device according to claim 16, characterized in that, the measurement method of the electronic sphygmomanometer includes inflation measurement and deflation measurement; when the measurement method of the electronic sphygmomanometer is the inflation measurement, the The pulse wave main wave amplitude and the dicrotic wave amplitude of the second pulse wave signal change from large to small over time until the user's arterial blood vessel is blocked and evolve into a stable process; when the electronic sphygmomanometer is measured by In the deflated measurement, the amplitude of the main pulse wave and the amplitude of the dicrotic wave of the second pulse wave signal are: from a stable process after the user's arterial vessel is blocked, to a change from small to large over time process.
An electronic device is characterized in that it includes a processor and a memory, the memory stores computer-executable instructions that can be executed by the processor, and when the electronic device is running, the processor executes the computer-executable instructions. Executing instructions to realize the blood pressure measuring method according to any one of claims 1 to 12.
A computer-readable storage medium, characterized in that computer-executable instructions are stored on the computer-readable storage medium, and when called and executed by a processor, the computer-executable instructions cause the processor to realize the The blood pressure measurement method described in any one of 1 to 12.
A computer program product, characterized by comprising a computer program, which when called and executed by a processor causes the processor to implement the blood pressure measurement method according to any one of claims 1 to 12.