CN112426141B - Blood pressure detection device and electronic device - Google Patents

Blood pressure detection device and electronic device Download PDF

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Publication number
CN112426141B
CN112426141B CN202011432872.7A CN202011432872A CN112426141B CN 112426141 B CN112426141 B CN 112426141B CN 202011432872 A CN202011432872 A CN 202011432872A CN 112426141 B CN112426141 B CN 112426141B
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blood pressure
user
pressure
signal
ppg
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CN112426141A (en
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李华飞
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Shenzhen Goodix Technology Co Ltd
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Shenzhen Goodix Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02108Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802Sensor mounted on worn items

Abstract

The blood pressure detection device and the electronic equipment have accurate blood pressure detection results and are convenient to detect. The blood pressure detection device includes: a processor configured to: acquiring blood pressure calibration information, wherein the blood pressure calibration information is information obtained by processing according to a first pressure acting on a user and a first PPG signal when the first pressure acts on the user; acquiring a second PPG signal, and processing according to the second PPG signal to obtain the initial blood pressure of the user; and calibrating the initial blood pressure according to the blood pressure calibration information, and taking the blood pressure obtained by calibration as the blood pressure of the user. In the technical scheme, the blood pressure calibration information determined according to the first PPG signal and the first pressure is directly obtained according to the blood pressure detection device without assistance of external equipment such as a sphygmomanometer, and the initial blood pressure determined according to the second PPG signal is obtained.

Description

Blood pressure detection device and electronic device
Technical Field
The present application relates to the field of electronics, and more particularly, to a blood pressure detection device and an electronic apparatus.
Background
Blood pressure is one of the important parameters for measuring the cardiovascular system of human body, and has important significance in disease diagnosis, treatment process and prognosis judgment. Currently, the mature blood pressure detection method in the market is a cuff type detection method based on an auscultation method or an oscillography method, wherein the auscultation method requires a professional operator to judge the blood pressure based on the sound of brachial artery blood flow, and is suitable for medical scenes; the oscillometric method is to inflate the cuff to block arterial blood flow, then detect the pressure of the air in the cuff and extract weak pulse wave in the process of exhausting, and detect the blood pressure value according to the change of the pulse wave along with the pressure in the cuff.
Along with the development of living standard, the sphygmomanometer adopting the cuff-type detection method gradually enters more daily scenes, and the accuracy of blood pressure measurement and the portability of the sphygmomanometer are very important for patients with hypertension, and although the sphygmomanometer adopting the cuff-type detection method has more accurate blood pressure measurement, the sphygmomanometer is not easy to carry, cannot meet all-weather blood pressure monitoring and cannot meet the requirements of patients with hypertension.
Therefore, the blood pressure detection device which has accurate blood pressure detection results, can be conveniently carried and has great application prospect and market value.
Disclosure of Invention
The embodiment of the application provides a blood pressure detection method, a blood pressure detection device and electronic equipment, which have accurate blood pressure detection results and are convenient to detect.
In a first aspect, a blood pressure detection method is provided, applied to a blood pressure detection device, including:
acquiring blood pressure calibration information, wherein the blood pressure calibration information is obtained by processing a first photoplethysmography (PPG) signal according to a first pressure acting on a user and a first photoplethysmography when the first pressure acts on the user;
acquiring a second photoplethysmography (PPG) signal, and processing according to the second PPG signal to obtain the initial blood pressure of the user;
and calibrating the initial blood pressure according to the blood pressure calibration information, and taking the blood pressure obtained by calibration as the blood pressure of the user.
In the technical solution of the embodiment of the present application, when the second PPG signal is detected, the accuracy of the blood pressure measured based on the second PPG signal is low. At this time, the blood pressure calibration information determined according to the first PPG signal and the first pressure is directly obtained according to the blood pressure detection device without assistance of an external device such as a sphygmomanometer, and is provided to the initial blood pressure determined according to the second PPG signal, the blood pressure calibration information calibrates the initial blood pressure, and the more accurate blood pressure obtained by calibration is used as the blood pressure of the user. In addition, if the blood pressure value is determined only by the first PPG signal and the first pressure, the first pressure is required to act on the user each time the blood pressure is detected, and the operation is complex and causes bad experience to the user. In the embodiment of the application, the blood pressure calibration information obtained by previous processing can be obtained to calibrate the initial blood pressure obtained according to the second PPG signal, so that the first pressure is not required to act on a user when blood pressure is detected each time, the first pressure and the first PPG signal are detected, and further the accuracy of blood pressure detection can be further improved, and meanwhile, the convenience of blood pressure detection and user experience can be improved.
In some possible embodiments, the acquiring blood pressure calibration information includes: driving a pressing module to press the user so as to form the first pressure; controlling a first pulse wave detection module to detect the first PPG signal when the first pressure acts on the user; the control pressure detection module detects the first pressure; the first pressure and the first PPG signal are received, and the blood pressure calibration information is determined according to the first pressure and the first PPG signal.
In some possible embodiments, the acquiring blood pressure calibration information includes: the control prompt module outputs a prompt signal which is used for prompting the user to apply pressure to the blood pressure detection device so as to form the first pressure; controlling a first pulse wave detection module to detect the first PPG signal when the first pressure acts on the user; the control pressure detection module detects the first pressure; the first pressure and the first PPG signal are received, and the blood pressure calibration information is determined according to the first pressure and the first PPG signal.
In some possible embodiments, the first pressure is either greater or lesser than the second pressure over time.
In some possible embodiments, the acquiring a second photoplethysmography, PPG, signal and processing according to the second PPG signal to obtain the initial blood pressure of the user comprises: controlling a second pulse wave detection module to detect the second PPG signal of the user; and receiving the second PPG signal, and processing the second PPG signal by adopting a pulse wave analysis method or a pulse wave conduction time measurement method to obtain the initial blood pressure of the user.
In some possible embodiments, the first pressure varies over time, the determining the blood pressure calibration information from the first pressure and the first PPG signal comprises: sorting the first PPG signals corresponding to the first pressure according to the magnitude of the first pressure to form envelope signals of the first PPG signals; determining a first blood pressure of the user from the envelope signal; the first blood pressure is used as the blood pressure calibration information.
In some possible embodiments, the calibrating the initial blood pressure according to the blood pressure calibration information, taking the calibrated blood pressure as the blood pressure of the user, includes: taking the blood pressure calibration information as a direct current component of the blood pressure of the user, and taking the initial blood pressure as an alternating current component of the blood pressure of the user; and calibrating the alternating current component of the blood pressure of the user according to the direct current component of the blood pressure of the user, and taking the calibrated blood pressure as the blood pressure of the user.
In some possible embodiments, before the acquiring the second photoplethysmography PPG signal, the blood pressure detection method further comprises: determining whether the user is in motion; if not, acquiring the second PPG signal; if so, after a preset time period, whether the user is in a motion state is determined again.
In some possible embodiments, the acquiring the first photoplethysmography, PPG, signal comprises: acquiring the first PPG signal at a first location of the user; the acquiring a second photoplethysmography, PPG, signal comprises: the second PPG signal is acquired at a second location of the user, wherein the second location is different from the first location.
In some possible embodiments, the first location is a finger of the user and the second location is a wrist of the user.
In a second aspect, a blood pressure detection device is provided, comprising a processor configured to: acquiring blood pressure calibration information, wherein the blood pressure calibration information is obtained by processing a first photoplethysmography (PPG) signal according to a first pressure acting on a user and a first photoplethysmography when the first pressure acts on the user; acquiring a second photoplethysmography (PPG) signal, and processing according to the second PPG signal to obtain the initial blood pressure of the user; and calibrating the initial blood pressure according to the blood pressure calibration information, and taking the blood pressure obtained by calibration as the blood pressure of the user.
In some possible implementations, the processor is configured to: driving a pressing module to press the first pressure to the user so as to form the first pressure; controlling a first pulse wave detection module to detect the first PPG signal when the first pressure acts on the user; the control pressure detection module detects the first pressure; the first pressure and the first PPG signal are received, and the blood pressure calibration information is determined according to the first pressure and the first PPG signal.
In some possible embodiments, the blood pressure detection device further comprises: the pressure applying module is electrically connected with the processor, and the first pulse wave detecting module is electrically connected with the processor.
In some possible implementations, the processor is configured to: the control prompt module outputs a prompt signal which is used for prompting the user to apply pressure to the blood pressure detection device so as to form the first pressure; controlling a first pulse wave detection module to detect the first PPG signal when the first pressure acts on the user; the control pressure detection module detects the first pressure; the first pressure and the first PPG signal are received, and the blood pressure calibration information is determined according to the first pressure and the first PPG signal.
In some possible embodiments, the blood pressure detection device further comprises: the prompting module is electrically connected with the processor, and the first pulse wave detection module is electrically connected with the processor.
In some possible embodiments, the first pressure is either greater or lesser than the second pressure over time.
In some possible implementations, the processor is configured to: controlling a second pulse wave detection module to detect the second PPG signal of the user; and receiving the second PPG signal, and processing the second PPG signal by adopting a pulse wave analysis method or a pulse wave conduction time measurement method to obtain the initial blood pressure of the user.
In some possible embodiments, the blood pressure detection device further comprises: the second pulse wave detection module is electrically connected with the processor.
In some possible implementations, the first PPG signal varies with the magnitude of the first pressure; the processor is configured to: sorting the first PPG signal according to the magnitude of the first pressure to form an envelope signal of the first PPG signal; determining a first blood pressure of the user from the envelope signal; the first blood pressure is used as the blood pressure calibration information.
In some possible implementations, the processor is configured to: taking the blood pressure calibration information as a direct current component of the blood pressure of the user, and taking the initial blood pressure as an alternating current component of the blood pressure of the user; and calibrating the alternating current component of the blood pressure of the user according to the direct current component of the blood pressure of the user, and taking the calibrated blood pressure as the blood pressure of the user.
In some possible implementations, before the processor is configured to obtain the second photoplethysmography PPG signal, the processor is further configured to: determining whether the user is in motion; if not, acquiring the second PPG signal; if so, after a preset time period, whether the user is in a motion state is determined again.
In some possible implementations, the processor is configured to: acquiring the first PPG signal at a first location of the user; the second PPG signal is acquired at a second location of the user, wherein the second location is different from the first location.
In some possible embodiments, the first location is a finger of the user and the second location is a wrist of the user.
In a third aspect, there is provided an electronic device comprising: the blood pressure detecting device of the second aspect or any one of the possible embodiments of the second aspect.
In some possible implementations, the electronic device is a smart watch.
Drawings
Fig. 1 is a block diagram of an electronic device to which the biological information detection system of the present application is applicable.
Fig. 2 is a schematic structural diagram of an apparatus for acquiring a photoplethysmography wave by using a photoelectric sensor.
Fig. 3 is a waveform characteristic diagram of a pulse wave.
Fig. 4 is a schematic diagram of the relative relationship between ECG waveform, PPG waveform, and PTT.
Fig. 5 is a schematic flow chart diagram of a blood pressure detection method according to an embodiment of the present application.
Fig. 6 is a schematic flow chart diagram of another blood pressure detection method according to an embodiment of the present application.
Fig. 7 is a schematic diagram of a prompt signal according to an embodiment of the present application.
Fig. 8 is a schematic flow chart diagram of another blood pressure detection method according to an embodiment of the present application.
Fig. 9 is a schematic flow chart diagram of another blood pressure detection method according to an embodiment of the present application.
Fig. 10 is a waveform schematic diagram of a first PPG signal as a function of first pressure according to an embodiment of the present application.
Fig. 11 is a schematic flow chart diagram of another blood pressure detection method according to an embodiment of the present application.
Fig. 12 is a schematic flow chart diagram of another blood pressure detection method according to an embodiment of the present application.
Fig. 13 is a schematic block diagram of a blood pressure detecting device according to an embodiment of the present application.
Fig. 14 is a schematic block diagram of another blood pressure detection device according to an embodiment of the present application.
Fig. 15 is a top view of a smart watch according to an embodiment of the present application.
Fig. 16 is a bottom view of the smart watch of fig. 15.
Fig. 17 is a side view of the smart watch of fig. 15.
Fig. 18 is a schematic block diagram of another blood pressure detection device according to an embodiment of the present application.
Fig. 19 is a bottom view of another smart watch according to an embodiment of the present application.
Detailed Description
The technical solutions in the embodiments of the present application will be described below with reference to the accompanying drawings.
It should be understood that the specific examples herein are intended only to facilitate a better understanding of the embodiments of the present application by those skilled in the art and are not intended to limit the scope of the embodiments of the present application.
It should also be understood that, in various embodiments of the present application, the size of the sequence number of each process does not mean that the execution sequence of each process should be determined by its functions and internal logic, and should not constitute any limitation on the implementation process of the embodiments of the present application.
It should also be understood that the various embodiments described in this specification may be implemented alone or in combination, and that the examples herein are not limited in this regard.
Unless defined otherwise, all technical and scientific terms used in the examples of this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the present application is for the purpose of describing particular embodiments only and is not intended to limit the scope of the present application. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
The present application is applicable to a biological information detection system including, but not limited to, a blood pressure detection system. The biological information detection system can be applied to various types of electronic devices, which can be intelligent wearable devices, mobile phones, tablet computers, mobile medical devices and the like, wherein the intelligent wearable devices can comprise at least one of the following devices: watches, bracelets, foot chains, necklaces, glasses, or head-mounted devices; the ambulatory medical device may include at least one of the following: blood glucose monitoring devices, heart rate monitoring devices, blood pressure measuring devices, body temperature measuring devices, etc., to which embodiments of the present application are not limited.
Fig. 1 is a block diagram showing a configuration of an electronic device to which the biological information detecting system of the present application is applied.
As shown in fig. 1, electronic device 10 may include a bus 110, a processor 120, a memory 130, an input/output interface 140, a display 150, a communication interface 160, and a biometric information detection system 170.
Bus 110 may include circuitry that enables communication (e.g., control messages or data) to be transferred between components in electronic device 10. Processor 120 may include one or more types of data processors for performing data processing. Memory 130 may include volatile memory and/or nonvolatile memory. Which may store instructions or data relating to other features in the electronic device 10.
The input/output interface 140 may be used to receive instructions or data input from a user or an external device and then transmit to other functional components in the electronic device 10, or may output instructions or data generated by other functional components in the electronic device 10 to a user or an external device.
The display 150 may include, for example, a liquid crystal display (Liquid Crystal Display, LCD), an Organic Light-Emitting Diode (OLED) display, or other type of display. The display 150 may display various types of content, such as text, images, video, icons, and the like, for a user. Further, the display 150 may include a touch screen through which a user may input related instruction information.
The communication interface 160 may be used to enable communication between the electronic device 10 and an external device, such as a web server or other electronic device. By way of example, the communication interface 160 may be connected to a communication network by wireless or wired communication to communicate with external devices. Wherein the wireless communication includes, but is not limited to, cellular communication or short-range communication. The wired communication includes, but is not limited to, at least one of universal serial bus (Universal Serial Bus, USB), high definition multimedia interface (High Definition Multimedia Interface, HDMI), recommended standard 232 (RS-232), or other communication means.
The biometric information detection system 170 is used to enable detection of biometric information of a user, including but not limited to: the parameter information such as heart rate, blood oxygen saturation, blood pressure of the user may be obtained by testing the pulse wave of the user, in other words, the biological information detection system 170 in the embodiment of the present application may be used to detect the pulse wave of the user, and obtain one or more types of biological characteristic information of the user based on the calculation and analysis of the pulse wave.
In some embodiments, the electronic device 10 may omit at least one of the above components, or may further include other components, which are not described in detail herein.
Specifically, the embodiment of the present application relates to a blood pressure detection method and a blood pressure detection apparatus, which can be applied to the biological information detection system 170 in fig. 1, and which is provided in the electronic device 10 in fig. 1. And more particularly, the embodiment of the application relates to a cuff-free blood pressure detection method and a blood pressure detection device based on pulse waves, which have the advantages of portability, continuous noninvasive measurement, high measurement accuracy and the like.
For ease of understanding, related concepts related to the present application will first be described.
(1) Pulse wave
Pulse waves refer to periodic fluctuations in the wall of an artery caused by periodic changes in pressure and volume within the artery during the periodic contraction and relaxation of the heart, i.e., periodic pulsations of the heart push blood along the blood vessel to produce pulse waves. Therefore, the pulse wave is affected by the heart function state, and is also affected by the vascular resistance, vascular elasticity, blood viscosity and the like flowing through each level of artery, and the change of the physiological characteristics of the cardiovascular system causes the change of the intensity, the morphology, the rhythm and the speed of the pulse wave signal. Therefore, the characteristics of the pulse wave signals can be analyzed and researched, the physiological and pathological information contained in the pulse wave signals can be extracted, and the method is helpful for early diagnosis and prevention of cardiovascular system related diseases.
The pulse wave is divided into pressure pulse wave and photoplethysmogram pulse wave, which reflect the periodical changes of the intravascular pressure and volume, respectively. The pressure pulse wave is usually detected and obtained at the superficial arteries such as radial artery, carotid artery or femoral artery, and the change curve of arterial pressure with time is traced by using a pressure sensor to obtain a pressure pulse wave waveform chart.
Photoplethysmogram is generally obtained by detecting with a photosensor, and is also often referred to as photoplethysmogram, and is generally detected by a photoplethysmography (Photo Plethysmography, PPG) method, and a change curve of a blood volume with time obtained by the photoplethysmography method is referred to as a photoplethysmogram waveform, hereinafter, photoplethysmogram is also referred to as a photoplethysmogram signal or PPG signal.
Specifically, fig. 2 shows a schematic diagram of the structure of an apparatus for acquiring a photoplethysmography wave using a photosensor.
As shown in fig. 2, when a light source emits a light beam with a certain wavelength to the surface of human skin (such as finger skin shown in fig. 2), the contraction and expansion of blood vessels each time of heartbeat affects the transmission of light (such as light passing through a fingertip in a transmitted PPG) or the reflection of light (such as light coming from the vicinity of the finger surface in a reflected PPG). When light passes through skin tissue and then reflects to the light detector, the illumination will be attenuated to some extent. The absorption of light by tissues like muscles, bones, veins and other connective tissues is substantially unchanged (if the measurement site does not move significantly), but arteries are different, and the absorption of light naturally varies due to pulsations of blood in the arteries. Therefore, after the light signal reflected and/or transmitted by the human body is converted into an electric signal by the light detector, the absorption of the light signal by the artery is changed, and the absorption of the light signal by other tissues is basically unchanged, so that the obtained signal can be divided into a Direct Current (DC) signal and an Alternating Current (AC) signal, and the characteristics of blood flow can be reflected by extracting the AC signal from the signal.
The two pulse wave waveforms have similar morphological characteristics, because the pressure pulse wave and the photoplethysmogram pulse wave are actually two different manifestations of the same arterial periodic pulse process, essentially reflecting the functional state of the cardiovascular system.
Fig. 3 shows a waveform characteristic diagram of a photoplethysmogram pulse wave.
As shown in fig. 3, a complete pulse wave waveform has a, B, C, D4 important feature points, which include ascending branches and descending branches. As shown in fig. 3, a is called a main wave, B is called a tidal wave, C is called a dicrotic wave peak, D is called a dicrotic wave trough, OA is a main rising branch, OO' is a pulse wave period.
The OA segment is the ascending branch of the pulse waveform, which is caused by the shrinkage of the left ventricle to eject blood, and the arterial blood pressure is rapidly increased, so as to form the expansion of the arterial wall. The O-point is the beginning of the cardiac ejection phase, the a-point is the highest aortic pressure point reflecting the maximum pressure and volume in the artery.
The AD section is the anterior section of the descending branch of the pulse waveform, and is caused by the process that the blood velocity begins to decrease in the later stage of ventricular ejection, so that the blood volume flowing into the periphery of the aorta is larger than that flowing into the aorta, the artery is changed from distention to retraction, and the arterial blood pressure gradually becomes lower. Point B is the left ventricular ejection stopping point, which is the peak point of the reflected wave, also called the tidal wave peak, reflecting the tension, compliance and peripheral resistance of the arterial vessel. The D point is the tidal wave trough point, i.e. the boundary point between systole and diastole.
The DO' segment is the posterior segment of the descending branch of the pulse waveform, also called the dicrotic wave, and is formed by the reflux of blood in the aorta in the ventricular direction due to the continuous decrease of the arterial blood pressure caused by the diastole of the ventricle. Reflecting the functional status of the aorta, vascular elasticity and blood flow status.
(2) Pulse transit time (Pulse Transit Time, PTT) and pulse velocity (Pulse Wave Velocity, PWV) measurements
Specifically, PTT refers to the conduction time of pulse wave from the heart to the measurement site when arterial ejection, and PWV can be calculated from PTT by the positional relationship between the measurement site and the heart. In the theory of the prior art, PWV has a linear relation with blood pressure, and the blood pressure can be calculated according to PWV or PTT and a related data model.
At present, since the pulse wave velocity PWV is difficult to measure, the existing PWV-based blood pressure detection methods all rely on PTT detection.
In some methods, PTT may be detected by Electrocardiography (ECG) in combination with PPG blood pressure detection techniques to estimate blood pressure.
Fig. 4 shows the relative relationship among ECG waveform, PPG waveform, and PTT.
As shown in fig. 4, in the ECG waveform, the R-wave represents the contraction of the ventricle, and the time interval between the R-wave in the ECG waveform and the main wave in the PPG waveform may be denoted as PPT. Or PPT may also be represented by the time interval before the R-wave in the ECG waveform reaches other feature points in the PPG waveform.
Specifically, the method is used for detecting the high-frequency component of the systolic blood pressure (Systolic Blood Pressure, SBP) according to PTT and a function equation, while the low-frequency component of the systolic blood pressure is needed to be measured by a more accurate blood pressure measurement method, such as an auscultation method or an oscillometric method, and the final more accurate value of the systolic blood pressure can be determined according to the sum of the low-frequency component and the high-frequency component of the systolic blood pressure. Further, a more accurate value of the diastolic pressure DPB may be obtained from the function equation between the PTT, the more accurate systolic pressure SBP, and the diastolic pressure (Diastolic Blood Pressure, DPB). In other words, according to the method, accurate blood pressure low-frequency components are required to be measured by external equipment such as a sphygmomanometer at regular intervals, and the blood pressure detected by the PPT detection method is calibrated, so that a more accurate blood pressure detection result is obtained.
(3) Pulse wave analysis (Pulse Wave Analysis, PWA)
Specifically, the characteristic parameters in the pulse wave can be extracted, the characteristic parameters with the best correlation with the blood pressure are found by analyzing the correlation between the characteristic parameters and the blood pressure, the characteristic parameters are used as the variable for measuring the blood pressure, regression analysis is carried out, and a regression function equation is established for measuring the blood pressure.
Alternatively, the amplitude of any feature point or the time difference between any two feature points in the pulse wave shown in fig. 3 may be used as the feature parameter, and the correlation analysis between the feature parameter and the blood pressure may be performed by a large amount of experimental data, and a regression function equation may be established. In the actual blood pressure measurement process, the pulse wave is detected, the characteristic parameters are extracted from the pulse wave, and then the blood pressure is measured according to the characteristic parameters and a regression function equation.
The blood pressure detected by the method is obtained by calculating a regression function equation, parameters obtained by artificial fitting are in the regression function equation, and along with time variation and human body difference, a certain error may exist in a blood pressure measurement result obtained by calculating the regression function equation. Therefore, the method also needs to calibrate the blood pressure measurement result regularly, that is, to measure accurate blood pressure through external devices such as a sphygmomanometer regularly, calibrate the blood pressure detected according to the PWA detection method or calibrate parameters in a regression equation, so as to obtain a more accurate blood pressure detection result. Therefore, based on the above description, although the above-described cuff-less blood pressure detection method can be used to obtain a pulse wave, and further the blood pressure is obtained by the pulse wave detection, it is possible to carry the blood pressure detection device with it. However, each of the above-described cuff-less blood pressure detection methods also has a problem of inaccurate blood pressure measurement and is troublesome to calibrate.
Based on the above, the cuff-free blood pressure detection method and device have the advantages of convenience, capability of continuous non-invasive measurement, high measurement accuracy and the like.
Fig. 5 shows a schematic flow chart of a blood pressure detection method 100 according to the present application. The blood pressure detection method 100 is applied to a blood pressure detection device, which may be a blood pressure detection device for detecting blood pressure information in the biological information detection system 170 of fig. 1, and optionally the blood pressure detection device includes a processor, which may be a subject of executing the blood pressure detection method 100 described below.
As shown in fig. 5, the blood pressure detection method 100 includes the following steps.
S110: blood pressure calibration information is acquired, wherein the blood pressure calibration information is information obtained through processing according to a first pressure acted on a user and a first photoplethysmography (PPG) signal when the first pressure acts on the user.
S120: and acquiring a second photoplethysmography (PPG) signal, and processing according to the second PPG signal to obtain the initial blood pressure of the user.
S130: and calibrating the initial blood pressure according to the blood pressure calibration information, and taking the blood pressure obtained by calibration as the blood pressure of the user.
Specifically, in step S110, the processor acquires a first pressure that can be applied to a user at a current time and a first photoplethysmography PPG signal when the first pressure is applied to the user, and the processor processes according to the first pressure and the first PPG signal to obtain blood pressure calibration information; alternatively, the processor directly invokes the blood pressure calibration information obtained at a previous time.
When the first pressure acts on the user, the blood vessel of the pressed part is deformed, the blood volume changes, and therefore, the first PPG signal changes along with the change of the first pressure, and therefore, the blood pressure calibration information can be determined according to the relation of the first PPG signal along with the change of the first pressure.
In step S120, when no pressure is applied to the user, the processor may acquire a second PPG signal of the user, and process to obtain an initial blood pressure according to the second PPG signal. The detection of the second PPG signal does not affect the user, can be obtained for a long time and continuously and is a noninvasive detection. However, since the second PPG signal does not include information about pressure variation, the accuracy of the initial blood pressure obtained by processing the second PPG signal is low, and if the initial blood pressure is directly provided to the user, the user experience is affected.
In step S130, the initial blood pressure is calibrated according to the blood pressure calibration information, so that a calibrated relatively accurate blood pressure can be obtained, and the blood pressure obtained by the calibration is used as the current blood pressure of the user and fed back to the user.
In the technical scheme of the embodiment of the application, the obtained second PPG signal is a PPG signal detected when no pressure acts on the body surface of the user, and the initial blood pressure accuracy obtained based on the second PPG signal is lower. At this time, calibration is performed without using external auxiliary equipment such as a sphygmomanometer, and the first PPG signal and the first pressure are directly obtained according to measurement of the blood pressure detection device, blood pressure calibration information is determined, the blood pressure calibration information is provided for initial blood pressure, the initial blood pressure is calibrated by using the blood pressure calibration information, and the calibrated accurate blood pressure is fed back to the user as the current blood pressure of the user. In addition, if the blood pressure value is determined only by the first PPG signal and the first pressure, the first pressure is required to act on the user each time the blood pressure is detected, and the operation is complicated and the user is not experienced well. In the embodiment of the application, the blood pressure calibration information obtained by previous processing can be obtained to calibrate the initial blood pressure obtained according to the second PPG signal, so that the first pressure is not required to act on a user when blood pressure is detected each time, the first pressure and the first PPG signal are detected, and further the accuracy of blood pressure detection can be further improved, and meanwhile, the convenience of blood pressure detection and user experience can be improved.
Alternatively, in step S110 described above, a first PPG signal at a first location of the user may be acquired, and in step S120 described above, a second PPG signal at a second location of the user may be acquired.
As can be appreciated in connection with the above description of fig. 2, the blood pressure detection device or the electronic device thereof comprises a PPG detection module comprising a light source and a light detector for detecting the first PPG signal and the second PPG signal.
In some embodiments, the first location and the second location are different locations of the user, in which case the blood pressure detection device or the electronic device in which it is located comprises a light source and a light detector corresponding to the two different locations, i.e. to the first light source and the first light detector at the first location of the user for detecting the first PPG signal at the first location; a second light source and a second light detector corresponding to a second location of the user for detecting a second PPG signal at the second location.
As an example, the first location of the user may be a finger of the user, e.g. an index finger, the first light source and the first light detector being controllable to detect the first PPG signal at the finger. The second location of the user may be the wrist of the user, and the second light source and the second light detector may be controlled to detect the second PPG signal at the wrist. Under this circumstance, the blood pressure detection device of the embodiment of the application can be arranged in the intelligent watch, the first light source and the first light detector can be correspondingly arranged on the side face of the intelligent watch, so that a user can conveniently detect the first pressure and the first PPG signal by pressing a finger to obtain blood pressure calibration information, and the second light source and the second light detector can be correspondingly arranged on the back face of the intelligent watch to detect the second PPG signal at the wrist, thus being convenient for the user to carry out blood pressure detection. For example, the second light source and the second light detector on the back side may facilitate long-term detection of the user's blood pressure (i.e., without requiring the user to press the wristwatch for a long period of time) to monitor the user's blood pressure for a long period of time, such as for example, to facilitate long-term and continuous blood pressure detection and monitoring during sleep states of the user. And the blood pressure calibration information obtained by the first pressure and the first PPG signal at the finger is used for calibrating the blood pressure obtained by the second PPG signal at the wrist, so that the convenient blood pressure detection can be realized, and the blood pressure detection result is accurate.
Of course, the first portion and the second portion may be the same portion of the user, for example, the first portion and the second portion are both the wrist of the user or are both other portions of the user, in which case the blood pressure detecting device or the electronic device thereof may only include a light source and a light detector corresponding to one portion, i.e. the electronic device may only include one light source and one light detector for respectively detecting the first PPG signal when the first pressure acts on the user and the second PPG signal when the pressure does not act on the user at different times, and if the blood pressure detecting device is disposed in the smart watch, the one light source and the one light detector may be disposed correspondingly on the back of the smart watch.
But preferably the first and second parts are respectively different parts of the user for the following reasons:
firstly, through testing PPG signals of different parts of a user, the PPG signals of different parts are synthesized to determine the blood pressure of the user, so that the accuracy of blood pressure test can be improved.
Secondly, if the first part is a finger, the second part is a wrist, and the movement amplitude of the wrist is smaller relative to the finger; and the wrist is suitable for wearing intelligent terminal equipment, for example, wearing of an intelligent watch, and the second PPG signal is derived from the wrist, so that the wearing equipment is more suitable for long-term continuous blood pressure detection, and the user experience can be improved.
Furthermore, the first part needs to apply pressure to the finger, the finger is convenient to apply pressure, the skin at the finger is thinner than the skin at the wrist, when the pressure signal acts on the finger, the generated first PPG signal changes obviously along with the first pressure, the accurate blood pressure calibration information can be obtained through detection, and the blood pressure calibration information is provided for the second PPG signal generated at the wrist, so that the accuracy of the blood pressure test at the wrist can be improved.
Alternatively, the first pressure may be applied to the user in a number of different ways.
For example, in the first embodiment, the first pressure is a pressure signal generated by the user, which may be, for example, a pressure signal generated by the first portion of the user pressing the blood pressure detecting device, for example, when the user's hand points to the blood pressure detecting device to apply pressure, the blood pressure detecting device will correspondingly apply a reaction force to the user's finger to form the first pressure.
In a second embodiment, the first pressure is a pressure signal generated by the blood pressure detecting device, and may be, for example, a pressure signal generated by the blood pressure detecting device applying pressure to a first portion of the user, for example, a pressure signal applied by the blood pressure detecting device itself to a finger of the user.
Next, the execution of the blood pressure detection method in the above two embodiments will be described with reference to fig. 6 to 8.
Fig. 6 shows a schematic flow chart of the blood pressure detection method 100 in the first embodiment described above.
As shown in fig. 6, the above step S110 may include the following steps.
S111: the control prompt module outputs a prompt signal which is used for prompting a user to apply pressure to the blood pressure detection device so as to form first pressure;
s113: controlling a first pulse wave detection module to detect a first PPG signal when a first pressure acts on a user;
s114: the control pressure detection module detects a first pressure;
s115: the first pressure and the first PPG signal are received, and blood pressure calibration information is determined from the first pressure and the first PPG signal.
Optionally, the alert signal includes, but is not limited to, one or more of a text signal, an image signal, a sound signal, a vibration signal, or a light signal, intended for interaction with a user. Correspondingly, in order to control the prompt module to output the prompt signals of different types, the blood pressure detection device or the electronic equipment where the blood pressure detection device is located may include prompt modules of different types.
For example, after receiving the presentation signal, the user applies pressure to the blood pressure detecting device through the first portion, and the blood pressure detecting device applies a reaction force to the first portion to form a first pressure to the first portion. At this time, the processor controls the blood pressure detecting device or the first pulse wave detecting module in the electronic device thereof to detect the first PPG signal when the first pressure acts on the user, and controls the blood pressure detecting device or the pressure detecting module in the electronic device thereof to detect the first pressure.
Then, the processor receives the first PPG signal transmitted by the first pulse wave detection module and the first pressure transmitted by the pressure detection module, and determines blood pressure calibration information according to the first pressure and the first PPG signal.
Optionally, the prompt signal may be an image signal or a video signal, and may show a specific pressing manner to the user, for example, at least part of functional modules in the blood pressure detection device, for example, the first pulse wave detection module is disposed on a side surface of the smart watch, and the prompt signal may prompt the user to press in a pressing manner shown in fig. 7, where an index finger of the user presses on one side surface of the watch, and a thumb presses on another side surface of the watch, and the first pulse wave detection module may be disposed under the thumb or the index finger, and by adopting this pressing manner, the pressing stability may be improved, so as to improve the detection accuracy of the first pressure and the detection accuracy of the first PPG signal.
Further, if the user's finger is pressed against the blood pressure detecting device, i.e. the first pressure acts on the user's finger, the first light source in the first pulse wave detecting module is controlled to be turned on at this time, and a first light signal is emitted to the user's finger, and the first light signal is received by the first light detector in the first pulse wave detecting module after being reflected and/or transmitted by the user's finger, so as to form a first PPG signal.
Optionally, in the embodiment of the present application, the first light source may emit an optical signal in a target band, where the target band includes, but is not limited to, a red light band or a green light band, to obtain a first PPG signal with better signal quality.
Optionally, the alert signal may also be used to alert the user as to the manner in which the pressure is applied, for example, increasing the applied pressure, or decreasing the applied pressure. After receiving the prompt signal, the user adjusts the pressing force with time, for example, first applies pressure to the blood pressure detecting device with a smaller pressing force, then gradually increases the pressing force, and for example, first applies pressure to the blood pressure detecting device with a larger pressing force, then gradually decreases the pressing force. Alternatively, the pressing force may be changed in any other manner, which is not particularly limited in the embodiment of the present application.
Further, when the pressing force of the user's finger is changed, the first pressure acting on the user's finger is changed with time, and the blood volume in the blood vessel inside the finger is also changed with time, and thus, the waveform of the first PPG signal is changed with time and corresponds to the different first pressure.
Fig. 8 shows a schematic flow chart of another blood pressure detection method 100 according to the second embodiment.
As shown in fig. 8, the above step S110 may include the following steps.
S112: the pressing module is driven to press the user to form a first pressure;
s113: controlling a first pulse wave detection module to detect a first PPG signal when a first pressure acts on a user;
s115: the first pressure and the first PPG signal are received, and blood pressure calibration information is determined from the first pressure and the first PPG signal.
Optionally, the blood pressure detection device or an electronic device in which the blood pressure detection device is located comprises a pressure application module, which may be used to apply pressure to a user. As an example, in embodiments of the present application, the processor may drive the pressure application module to apply pressure to the user to create the first pressure. The pressing module includes, but is not limited to, a motor drive unit or other type of drive unit, which is not specifically limited in the embodiments of the present application.
Further, when the pressure applying module is driven to apply pressure to a first portion of the user, such as a finger, the processor controls to turn on the first light source in the first pulse wave detecting module, and transmits a first light signal to the finger of the user, where the first light signal is reflected and/or transmitted by the finger of the user, and then is received by the first light detector in the first pulse wave detecting module to form a first PPG signal.
Alternatively, in some embodiments, the pressure application module may send the pressure it applies directly to the user as the first pressure to the processor.
Alternatively, in other embodiments, the blood pressure detecting apparatus or the electronic device thereof may include a pressure detecting module, and optionally, in the blood pressure detecting method 100 shown in fig. 8, before step S115, step S114 may further be included (the dashed box in fig. 8 indicates that this step is an optional step): the control pressure detection module detects a first pressure. Specifically, the processor may control the pressure detection module to detect the pressure applied by the pressure application module to the user, and obtain the first pressure and send the first pressure to the processor.
Alternatively, the pressure intensity of the pressure applied by the pressure applying module to the finger of the user may change with time, for example, the pressure intensity changes from small to large or from large to small with time, or may also change in any other manner, which is not specifically limited in the embodiments of the present application.
Further, when the pressure signal applied by the pressure applying module to the finger of the user changes, the first pressure acting on the finger of the user changes with time, and the blood volume in the blood vessel inside the finger also changes with time, so that the waveform of the first PPG signal changes with time and corresponds to the different first pressure.
By adopting the technical scheme of the embodiment of the application, the pressure is applied to the user through the control pressure applying module so as to form the first pressure, the situation that the user actively presses when detecting the blood pressure can be avoided, so that the user experience is improved, and compared with the pressing pressure of the user, the pressure applying module is controlled to provide the first pressure for the user, and the user can be prevented from pressing the blood pressure detecting device and the electronic equipment where the blood pressure detecting device is located to be damaged.
As is apparent from the above description of fig. 6 and 8, the magnitude of the first pressure acting on the user varies with time, and thus the detected first PPG signal varies with the magnitude of the first pressure.
In this case, fig. 9 shows a schematic flow chart of another blood pressure detection method 100.
As shown in fig. 9, the above step S115 may include the following steps.
S1151: the first PPG signals are ordered in order of magnitude of the first pressure, forming an envelope signal of the first PPG signals.
S1152: and determining the first blood pressure of the user according to the envelope signal, and taking the first blood pressure as blood pressure calibration information.
Optionally, in step S1151, the first PPG signals corresponding to different pressures are arranged in order of decreasing first pressure or increasing first pressure, to form an envelope signal of the first PPG signals. According to the sequence of the first pressure, the formed envelope signal of the first PPG signal can reflect the relation between the amplitude of the PPG signal and the change of the first pressure more accurately, and compared with the envelope signals obtained in other modes, the envelope signal formed in the mode has better signal quality, and the blood pressure detected according to the envelope signal has higher accuracy.
It is understood that step S1151 and step S1152 in fig. 9 are applied to the embodiment of the blood pressure detection method 100 shown in fig. 8, and that step S1151 and step S1152 are also applicable to the embodiment of the blood pressure detection method 100 shown in fig. 6.
Fig. 10 shows a trend of the corresponding first PPG signal when the first pressure is changed from small to large.
As can be seen from fig. 10, as the first pressure gradually increases, the amplitude of the first PPG signal gradually increases, and when the amplitude reaches the maximum, the amplitude of the first PPG signal gradually decreases until it disappears. Therefore, the amplitude of the envelope signal formed by the first PPG signal increases with pressure, and gradually decreases to zero with increasing pressure signal after reaching a maximum value.
In step S1152, as an embodiment, a first blood pressure of the user may be determined according to the waveform parameters of the envelope signal and a preset function equation, for example, a current diastolic blood pressure and systolic blood pressure of the user may be determined, and the first blood pressure may be directly used as blood pressure calibration information.
Optionally, the preset function equation may be a function equation determined according to multiple sets of experimental data, so as to improve the calculation reliability of calculating the blood pressure through the function equation and the waveform parameters of the envelope signal.
In order to ensure the accuracy of the blood pressure calibration information, optionally, before the above step S1152, the following steps may be performed:
judging whether the envelope signal meets the preset condition, if yes, executing the step S1151, otherwise, re-detecting a new PPG signal generated under a new pressure signal according to the processes of steps S111 and S113 shown in fig. 6 or steps S112 and S113 shown in fig. 8.
Specifically, whether the envelope signal meets the preset condition or not is judged, namely whether the signal quality of the envelope signal is good or bad is judged, if the signal quality of the envelope signal is bad, the change trend of the detected first PPG signal along with the change of the first pressure is not obvious, and the first blood pressure detected according to the envelope signal is inaccurate, namely the blood pressure calibration information is inaccurate.
Optionally, in an embodiment of the present application, the preset conditions of the envelope signal include, but are not limited to: the integrity of the envelope signal, the amplitude of the maximum amplitude of the envelope signal, the width of the envelope signal, etc., as embodiments of the present application are not specifically limited.
Optionally, in the above step, if the envelope signal does not meet the preset condition, it is determined whether the number of times of unsatisfied exceeds the threshold, if the number of times of unsatisfied exceeds the threshold, the blood pressure detection process is ended, and if the number of times of unsatisfied exceeds the threshold, a new PPG signal generated under the new pressure signal is re-detected according to the process of the above step S110.
By adopting the mode, the calibration process can be repeatedly carried out under the poor test condition, the system resource is wasted, and poor experience is brought to the user.
Fig. 11 shows a schematic flow chart of another blood pressure detection method 100.
As shown in fig. 11, as a possible implementation manner, the step S120 may include the following steps.
S121: controlling a second pulse wave detection module to detect a second PPG signal of the user;
s122: and receiving a second PPG signal, and processing the second PPG signal by adopting a pulse wave analysis method or a pulse wave conduction time measurement method to obtain the initial blood pressure of the user.
Optionally, in step S121, the second light source in the second pulse wave detection module is turned on under control of the target frequency in a preset period of time, and an optical signal of the second light source after being reflected and/or transmitted by the user is received by the second light detector in the second pulse wave detection module, so as to detect the second PPG signal.
As an example, the preset period of time is 1s, the target frequency is 50Hz, and the second light source is turned on multiple times at a frequency of 50Hz, i.e. the first light source is turned on once every 20ms, so as to detect the second PPG signal within 1 s.
Of course, the preset time period and the target frequency may be any other preset value, which is not specifically limited in the embodiment of the present application. It can be appreciated that the longer the preset time period and the higher the target frequency, the higher the detection accuracy of the second PPG signal.
Optionally, in the embodiment of the present application, the second light source may emit an optical signal in a target band, where the target band includes, but is not limited to, a red light band or a green light band, to obtain a second PPG signal with better signal quality.
Alternatively, in addition to controlling the second pulse wave detection module to detect the second PPG signal of the user in step S121, the first pulse wave detection module may be controlled to detect the second PPG signal of the user. Namely, the first pulse wave detection module is controlled to respectively detect a first PPG signal and a second PPG signal of the same part of the user in different time periods, wherein the first PPG signal is a PPG signal when a first pressure acts on the user, and the second PPG signal is a PPG signal when no pressure acts on the user.
Further, as shown in fig. 11, after the second PPG signal is detected in step S121, in step S122, the second PPG signal may be processed by the PTT measurement method or the PWA analysis method to obtain the initial blood pressure of the user, or other related technology methods may be further used to obtain the initial blood pressure of the user according to the second PPG signal, which is not limited in particular in the embodiment of the present application.
Specifically, if the PTT measurement method is used to measure the blood pressure, an ECG signal corresponding to the second PPG signal needs to be measured, and PTT is determined according to the ECG signal and the second PPG signal, so as to determine an ac component of the current blood pressure of the user, that is, an initial blood pressure.
Alternatively, as shown in fig. 11, the above step S130 may include the following steps.
S131: the blood pressure calibration information is taken as the direct current component of the user's blood pressure, and the initial blood pressure is taken as the alternating current component of the user's blood pressure.
S132: and calibrating the alternating current component of the blood pressure of the user according to the direct current component of the blood pressure of the user, and taking the calibrated blood pressure as the blood pressure of the user.
In this embodiment, the blood pressure calibration information acquired in step S110 may be the first blood pressure, and in steps S131 and S132, the first blood pressure is used as a direct current component of the current blood pressure of the user, the initial blood pressure is used as an alternating current component of the current blood pressure of the user, the current blood pressure of the user is determined from the first blood pressure and the initial blood pressure, and the current blood pressure of the user is fed back to the user as an output.
Alternatively, in other embodiments, in the process of processing the second PPG signal by using the PTT measurement method or the PWA analysis method, a function equation is used to calculate a blood pressure, and according to the blood pressure calibration information, for example, a first blood pressure, function equation parameters in the process of processing the second PPG signal are calibrated, so that an initial blood pressure calculated according to the second PPG signal and the calibrated function equation is close to or even equal to the first blood pressure, and the first blood pressure or the initial blood pressure is used as a current blood pressure of a user and is output and fed back to the user.
The blood pressure obtained through the mode is accurate, long-term and continuous blood pressure measurement can be realized, and user experience can be improved.
On the basis of the blood pressure detection method 100 shown in fig. 5 above, fig. 12 shows a schematic diagram of another blood pressure detection method 100.
As shown in fig. 12, the blood pressure detection method 100 may further include:
s140: it is determined whether the user is in motion.
If not, step S120 and step S130 are executed to obtain a second PPG signal, process the second PPG signal to obtain an initial blood pressure of the user, and determine the blood pressure of the user according to the blood pressure calibration information and the initial blood pressure.
If so, step S120 and step S130 are not executed, and step S140 is executed again after a predetermined period of time, i.e. whether the user is in a motion state is determined again.
Since the relative movement between the optical sensor (including the light source and the light detector) and the skin reduces the sensitivity of the optical signal, if the user is in motion, a larger disturbance is caused to the detection of the second PPG signal. Therefore, before the second PPG is acquired, the state of the user is judged, and the second PPG signal is detected and acquired when the user is in a non-motion state, so that the accuracy of blood pressure detection can be improved.
Alternatively, the state of the user may be sensed by a motion sensor, including but not limited to an accelerometer, where the accelerations of the three axes XYZ are all 0 if the user is in a stationary state, and the second PPG signal quality tested is the best.
In some embodiments, it may be determined whether the user is in motion by determining whether the accelerations of the XYZ three axes in the accelerometer are within a preset threshold. The preset thresholds may be all 0, or at least one of them is 0, or other preset thresholds, which is not specifically limited in the embodiments of the present application.
The above description is made with reference to fig. 5 to fig. 12, which illustrate a plurality of blood pressure detection methods provided in the embodiments of the present application, in which the same blood pressure detection device is used, in a blood pressure detection process, two detection modes are adopted to detect and obtain different PPG signals, and the results obtained in the two detection modes are combined to determine the blood pressure of the user together, so that the accuracy of blood pressure detection is improved while convenient blood pressure detection is realized.
In addition, it should be noted that, when the first PPG signal is detected, the first pressure needs to act on the user body surface, and in one measurement process, the first pressure is a pressure signal acting on the user in a short time, and the blood pressure measured by this method is accurate but not suitable for long-time or frequent use for blood pressure detection, and long-time or frequent application of pressure to the user body surface may cause poor user experience.
In order to solve the above-mentioned problems, another blood pressure detecting method is provided according to the embodiment of the present application, and on the basis of the above-mentioned blood pressure detecting method 100, that is, on the basis of determining the blood pressure calibration information, in the subsequent blood pressure detecting process, before the blood pressure detection, it is first determined whether the calibration is updated at present, and if the calibration is updated, new blood pressure calibration information is obtained again, where the new blood pressure calibration information is obtained according to the first PPG signal when the first pressure is applied to the user again and the new blood pressure calibration information obtained by the reapplied first pressure processing. In addition, a new second PPG signal when no pressure acts on the user is acquired again, a new initial blood pressure is determined, and the new initial blood pressure is calibrated by combining the new blood pressure calibration information, so that the new blood pressure of the user is determined. If the calibration is not updated, the previous blood pressure calibration information is directly called, a new second PPG signal without pressure acting on the user is obtained, the new initial blood pressure is determined, and then the new initial blood pressure is directly calibrated based on the previous blood pressure calibration information, so that the new blood pressure of the user is determined.
As one implementation, before acquiring the blood pressure calibration information, it may be determined whether to perform the calibration based on first information including, but not limited to: current time information and/or user input information.
Specifically, if the first information is the current time information, determining whether the current time information is within a preset time range, if the current time information is within the preset time range, performing calibration, otherwise, if the time information is not within the preset time range, not performing calibration.
As an example, the preset time range may be a time period preset by the user, such as the same time period of each month, or a time period of each day, or any other preset time period. The time information is current time information, and whether the current time is within a preset time period is judged to judge whether the blood pressure detection device is calibrated.
Specifically, if the first information is user input information, the user input information is used for indicating whether the user needs to calibrate the blood pressure detection device, and the blood pressure detection device is calibrated according to the user requirement.
Optionally, in this embodiment of the present application, a preset time period is taken as a period, the blood pressure of the user may be continuously detected, and when the blood pressure of the user is detected each time, whether to perform calibration may be flexibly determined according to the first information, for example, the current time information and/or the user input information, or the like, that is, whether to obtain new blood pressure calibration information is determined.
The blood pressure detecting method provided in the present application is described above with reference to fig. 5 to 12, and the blood pressure detecting device provided in the present application is described below with reference to fig. 13 to 19, and it is understood that the blood pressure detecting device described in the following embodiments may be a device for performing the blood pressure detecting method described above, and relevant technical features may be referred to the relevant description above.
As shown in fig. 13, a blood pressure detecting apparatus 101 may include: a processor 11, the processor 11 being configured to:
acquiring blood pressure calibration information, wherein the blood pressure calibration information is obtained by processing a first photoplethysmography (PPG) signal according to a first pressure acting on a user and a first photoplethysmography when the first pressure acts on the user;
acquiring a second photoplethysmography (PPG) signal, and processing according to the second PPG signal to obtain the initial blood pressure of the user;
and calibrating the initial blood pressure according to the blood pressure calibration information, and taking the blood pressure obtained by calibration as the blood pressure of the user.
Alternatively, in other embodiments, the processor 11 is configured to:
the control prompt module 15 outputs a prompt signal for prompting the user to apply pressure to the blood pressure detection device to form the first pressure;
Controlling a first pulse wave detection module 13 to detect the first PPG signal when the first pressure acts on the user;
the control pressure detection module 14 detects a first pressure;
the first pressure and the first PPG signal are received, and the blood pressure calibration information is determined according to the first pressure and the first PPG signal.
Optionally, as shown in fig. 14, the blood pressure detecting device 101 in the embodiment of the present application may further include the above-mentioned prompting module 15, the first pulse wave detecting module 13, and the pressure detecting module 14.
Alternatively, the first pulse wave detection module 13 may include: a first light source 121, a first light detector 122, and a first signal processing module 123.
Optionally, the first light source 121 is configured to emit a first light signal to a first location of a user, where a first pressure acts on the first location of the user, where the first light signal is received by the first light detector 122 after being reflected and/or transmitted by a blood vessel in the first location, and the first light detector 122 performs photoelectric conversion on the received light signal, and then transmits the formed electrical signal to the first signal processing module 123 for signal processing, so as to form a first PPG signal.
Optionally, the first Light source 121 includes, but is not limited to, one or more point-like Light sources, such as a Light-Emitting Diode (LED), a Laser Diode (LD), or an infrared Emitting Diode, which may also be a linear Light source or a planar Light source, which is not specifically limited in this embodiment of the present application. The first light source 121 may be configured to emit a first light signal in one or more target wavelength bands, which may be, for example, a red wavelength band or a green wavelength band.
Optionally, the first photodetector 122 includes, but is not limited to, a Photodiode (PD), a phototransistor, or the like, which is used for photoelectric conversion. The first signal processing module 123 may include: the signal processing circuits such as the amplifying circuit, the low-pass filter circuit, the analog-to-digital conversion circuit and the like are used for optimizing the signal quality so as to improve the blood pressure detection effect.
Alternatively, a pressure sensor may be included in the pressure detection module 14 for sensing the first pressure, including but not limited to: piezoelectric pressure sensors, piezoresistive pressure sensors, capacitive pressure sensors, inductive pressure sensors, or other types of pressure sensors, as embodiments of the present application are not specifically limited in this regard.
In particular, the first light source 121 and the first light detector 122 may be located on the same side or opposite side of the first portion of the user for receiving reflected light and/or transmitted light after passing through the first portion to form the first PPG signal.
As an example, the first light source 121 and the first light detector 122 are both located on the same side of the first part of the user, e.g. the blood pressure detection device 101 is provided on the smart watch, the first light source 121 and the first light detector 122 are arranged adjacent, which may be located at the side of the smart watch or in a key at the side of the smart watch.
Alternatively, the pressure detection module 14 may be disposed at a side of the smart watch together with the first light source 121 and the first light detector 122, which may be disposed stacked with the first light source 121 and the first light detector 122, or may be disposed horizontally with the first light source 121 and the first light detector 122.
Specifically, the processor 11 is configured to control the prompting module 12 to output a prompting signal for prompting the user to apply pressure to the blood pressure detecting device to form a first pressure;
optionally, the alert signal includes, but is not limited to, one or more of a text signal, an image signal, a sound signal, a vibration signal, or a light signal, intended for interaction with a user. Correspondingly, the prompt module 12 includes, but is not limited to, a display unit, a lighting unit, a sound unit, a vibration unit, or the like.
After receiving the prompt signal, the user applies pressure to the blood pressure detecting device 101 through the first portion to generate a first pressure at the first portion, and as an example, the prompt module 12 is a display unit, for example, a display screen of the smart watch may be multiplexed into the prompt module 12, where the display screen is used for outputting the prompt signal, for example, outputting a pressing gesture picture or video shown in fig. 7, and after receiving the prompt signal, the user presses his finger against the side of the watch in a manner shown in fig. 7, where the finger presses against a button on the side of the watch, that is, presses against a position corresponding to the first light source 121 and the first light detector 122.
Alternatively, the prompting signal may be used to prompt the user to press the intensity of the blood pressure detection device 101 from large to small or from small to large, and then the first pressure detected by the pressure detection module 14 is from large to small or from small to large. The user applies pressure to the blood pressure detection device 101 according to the mode, the variation trend of the first pressure is the same, and the processor 11 can conveniently sort the first PPG signals corresponding to the first pressure according to the magnitude of the first pressure, so as to obtain envelope signals with good signal quality, and the envelope signals are used for detecting the blood pressure of the user to obtain blood pressure correction information.
Fig. 15 to 17 show a top view, a bottom view and a side view of a smart watch, specifically, fig. 15 is a top view of the smart watch, that is, a front surface of the smart watch; fig. 16 is a bottom view of the smart watch, i.e., the back side of the smart watch; fig. 17 is a side view of the smart watch, i.e., the side of the smart watch.
As shown in fig. 15 to 17, the first light source 121 and the first light detector 122 are disposed on the side keys of the smart watch, and the pressure detection module 14 is disposed on one side of the first light source 121 and the first light detector 122 near the inside of the watch, and is stacked with the first light source 121 and the first light detector 122.
It should be noted that, in the embodiment shown in fig. 15 to 17, the pressure detection module 14 may be located inside the watch, and the first light source 121 and the first light detector 122 may be disposed inside the key, so the pressure detection module 14, the first light source 121 and the first light detector 122 are indicated by dashed boxes in fig. 15 to 17.
Optionally, the processor 11 is further configured to: controlling the second pulse wave detection module 13 to detect a second PPG signal of the user;
and receiving a second PPG signal, and processing the second PPG signal by adopting a pulse wave analysis method or a pulse wave conduction time measurement method to obtain the initial blood pressure of the user.
Optionally, as shown in fig. 14, the blood pressure detecting device 101 of the embodiment of the present application may further include the above-mentioned second pulse wave detecting module 13.
As an example, the second pulse wave detection module 13 may include: a second light source 131, a second light detector 132 and a second signal processing module 133.
Specifically, the second light source 131 may be one or more point-like light sources, and is configured to emit second optical signals of different target bands to a second portion of the user, where the second optical signals are received by the second light detector 132 after being reflected or transmitted by a blood vessel in the second portion, and the number of the second light detectors 132 may also be one or more, and the one or more second light detectors 132 photoelectrically convert the received optical signals and then transmit the formed electrical signals to the second signal processing module 133 for signal processing to form a second PPG signal.
Alternatively, the second light source 131 and the second light detector 132 may be located on the same side of the second portion of the user, for example, the blood pressure detecting device 101 is disposed on the smart watch, and the second light source 131 and the second light detector 132 are disposed adjacent to each other, which may be located on the back side of the smart watch.
As shown in fig. 15 to 17, the smart watch includes a plurality of second light sources 131 and a plurality of second light detectors 132, wherein the plurality of second light sources 131 can emit second light signals with at least two different wavelength bands, the plurality of second light sources 131 are disposed at a central portion of a back surface of the watch, and the plurality of second light detectors 132 surround the plurality of second light sources 131.
As shown in fig. 14, in the embodiment of the present application, the processor 11 is configured to perform signal interaction with the first pulse wave detection module 12, the second pulse wave detection module 13, the prompt module 15, and the pressure detection module 14, and may be used to generate control signals to control the first pulse wave detection module 12, the second pulse wave detection module 13, the prompt module 15, and the pressure detection module 14 to perform corresponding functional actions, and may also be used to receive various signals detected by the first pulse wave detection module 12, the second pulse wave detection module 13, and the pressure detection module 14, for example, the first pressure, the first PPG signal, the second PPG signal, and the like, and perform signal processing on the various signals to obtain a blood pressure detection result.
Alternatively, in other embodiments, the processor 11 is configured to:
driving the pressing module 16 to press the first pressure to the user so as to form the first pressure;
control the first pulse wave detection module 12 to detect the first PPG signal when the first pressure acts on the user;
the first pressure and the first PPG signal are received, and the blood pressure calibration information is determined according to the first pressure and the first PPG signal.
Alternatively, in some embodiments, the first pressure received by the processor 11 may be the first pressure to which the pressure application module 16 sends.
Optionally, in other embodiments, the processor 11 is further configured to: the control pressure detection module 14 detects the first pressure. The first pressure received by the processor 11 is the first pressure to which the pressure detection module 14 sends.
Optionally, as shown in fig. 18, the blood pressure detecting device 101 in the embodiment of the present application may further include the above-described pressure applying module 16 and the first pulse wave detecting module 12.
Optionally, in some embodiments, the blood pressure detection device 101 may further include: a pressure detection module 14.
Further, the blood pressure detecting device 101 may further include: the second pulse wave detection module 13.
Specifically, in the embodiment of the present application, the first pulse wave detection module 12, the second pulse wave detection module 13 and the pressure detection module 14 may refer to the related descriptions of fig. 14, and are not described in detail herein.
In the present embodiment, the processor 11 is configured to control the pressing module 16 to apply pressure to the user to form the first pressure. Optionally, the processor 11 is configured to control the intensity of the pressing module to the user to be changed from large to small or from small to large, and thus the first pressure formed is changed from large to small or from small to large. In some embodiments, the pressure application module 16 includes, but is not limited to, a motor drive module or other type of drive module, as the present embodiments are not specifically limited.
Alternatively, if the first light source 121 and the first light detector 122 are disposed on the key of the wristwatch, the pressing module 16 may be disposed on one side of the key for providing pressure to the key.
Fig. 19 shows a bottom view of a smart watch including a pressure applying module 16, i.e., a schematic back view of the smart watch.
As an example, as shown in fig. 19, the pressing module 16 may be disposed between the first light source 121, the first light detector 122 and the pressure detection module 14, so that the first light source 121 and the first light detector 122 can detect the first PPG signal, and can also facilitate the detection of the pressure by pressing the module where the first light source 121 and the first light detector are located, and further, pressing the user to generate the first pressure, and in addition, the pressing module 16 is disposed adjacent to the pressure detection module 14, so that the pressure detection module 14 can also perform the pressure detection.
It will be appreciated that, in addition to the pressing module 16, other functional modules in fig. 18 and 19 may be referred to in the description related to fig. 15 to 18 above, and will not be described again here. In addition, fig. 15 to 17, and fig. 19 only illustrate the related structure of the blood pressure detecting device 101 provided in the embodiment of the present application by taking the smart watch as an example, and the blood pressure detecting device 101 in the embodiment of the present application is not limited to being provided only on the smart watch, but may be provided in any other type of electronic device such as a mobile phone, a computer, or a biological information detecting device, and the embodiment of the present application is not limited thereto specifically.
Further, the processor 11 may be configured to implement the relevant steps in the blood pressure detection method 100 above, in addition to being configured to implement the relevant functions described in fig. 13, 14 and 18 above.
Optionally, for the first pressure and the first PPG signal, the processor 11 may be configured to: sorting the first PPG signals according to the magnitude of the first pressure to form envelope signals of the first PPG signals; determining a first blood pressure of a user according to waveform parameters of the envelope signal and a preset function equation; and taking the first blood pressure as blood pressure calibration information.
Alternatively, for a calibration procedure of blood pressure calibration information with initial blood pressure, the processor 11 may be configured to: and taking the initial blood pressure as an alternating current component of the blood pressure of the user, taking the blood pressure calibration information as a direct current component of the blood pressure of the user, and calibrating to obtain the blood pressure of the user.
In some embodiments, before processor 11 is configured to acquire the second PPG signal, processor 11 is further configured to: determining whether the user is in a motion state;
if not, the processor 11 is configured to: acquiring a second PPG signal;
if yes, the processor 11 is configured to: after a preset period of time, it is re-determined whether the user is in motion.
In some embodiments, the processor 11 is configured to: judging whether the acceleration value of the accelerometer is within the range of a preset threshold value, and determining whether the user is in a motion state.
Alternatively, in some implementations, the blood pressure detection device 101 of the present embodiments may include an accelerometer or other type of motion sensor. In other embodiments, the accelerometer or other type of motion sensor may also be disposed in the electronic device in which the blood pressure detecting device 101 is located, which is not specifically limited in this embodiment.
Optionally, the processor 11 is configured to: acquiring a first PPG signal at a first location of a user;
a second PPG signal is acquired at a second location of the user, wherein the second location is different from the first location.
Optionally, the first part is a finger of the user and the second part is a wrist of the user.
The embodiment of the present application further provides a blood pressure detecting device, including a processor and a memory, where the memory is configured to store a computer program, and the processor is configured to invoke the computer program to execute the blood pressure detecting method 100 in any of the embodiments of the present application.
The embodiment of the present application further provides an electronic device, which may include the blood pressure detecting apparatus 101 in any of the embodiments of the present application.
Alternatively, the electronic device may be a smart watch or a mobile phone, and the blood pressure detecting device 101 may be disposed on any surface of the electronic device, for example, on a back surface or a side surface of the electronic device.
Further, the above-mentioned blood pressure detecting device 101 may be disposed in a key on the surface of the electronic device, where the key may be used only for realizing blood pressure detection, or may be used for realizing other functions of the electronic device based on realizing blood pressure detection.
It should be appreciated that the processing unit or processor of embodiments of the present application may be an integrated circuit chip with signal processing capabilities. In implementation, the steps of the above method embodiments may be implemented by integrated logic circuits of hardware in a processor or instructions in software form. The processor may be a general purpose processor, a digital signal processor (Digital Signal Processor, DSP), an application specific integrated circuit (Application Specific Integrated Circuit, ASIC), an off-the-shelf programmable gate array (Field Programmable Gate Array, FPGA) or other programmable logic device, discrete gate or transistor logic device, discrete hardware components. The disclosed methods, steps, and logic blocks in the embodiments of the present application may be implemented or performed. It will be appreciated that the blood pressure detection device of embodiments of the present application may also include a memory unit or memory, which may be volatile memory or nonvolatile memory, or may include both volatile and nonvolatile memory.
The present application also proposes a computer readable storage medium storing one or more programs, the one or more programs comprising instructions, which when executed by a portable electronic device comprising a plurality of application programs, enable the portable electronic device to perform the method of the above-presented embodiments.
The present application also proposes a computer program comprising instructions which, when executed by a computer, cause the computer to perform the method of the embodiments shown above.
Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware, or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the solution. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.
In the several embodiments provided in this application, it should be understood that the disclosed systems, devices, and methods may be implemented in other manners. For example, the apparatus embodiments described above are merely illustrative, e.g., the division of the units is merely a logical function division, and there may be additional divisions when actually implemented, e.g., multiple units or components may be combined or integrated into another system, or some features may be omitted or not performed. Alternatively, the coupling or direct coupling or communication connection shown or discussed with each other may be an indirect coupling or communication connection via some interfaces, devices or units, which may be in electrical, mechanical or other form.
The units described as separate units may or may not be physically separate, and units shown as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.
In addition, each functional unit in each embodiment of the present application may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit.
The functions, if implemented in the form of software functional units and sold or used as a stand-alone product, may be stored in a computer-readable storage medium. Based on such understanding, the technical solutions of the present application may be embodied in essence or a part contributing to the prior art or a part of the technical solutions, or in the form of a software product, which is stored in a storage medium and includes several instructions to cause a computer device (which may be a personal computer, a server, or a network device, etc.) to perform all or part of the steps of the methods described in the embodiments of the present application. And the aforementioned storage medium includes: a U-disk, a removable hard disk, a Read-Only Memory (ROM), a random access Memory (Random Access Memory, RAM), a magnetic disk, or an optical disk, or other various media capable of storing program codes.
The foregoing is merely specific embodiments of the present application, but the scope of the present application is not limited thereto, and any person skilled in the art can easily think about changes or substitutions within the technical scope of the present application, and the changes and substitutions are intended to be covered by the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims (13)

1. A blood pressure detection device comprising a processor configured to:
acquiring blood pressure calibration information, wherein the blood pressure calibration information is obtained by processing a first photoplethysmography (PPG) signal according to a first pressure acting on a user and a first photoplethysmography when the first pressure acts on the user;
acquiring a second photoplethysmography (PPG) signal, and processing according to the second PPG signal to obtain the initial blood pressure of the user;
calibrating the initial blood pressure according to the blood pressure calibration information, and taking the blood pressure obtained by calibration as the blood pressure of the user;
wherein the first photoplethysmography, PPG, signal varies with the magnitude of the first pressure;
the processor is configured to: sorting the first photoplethysmography PPG signals according to the magnitude of the first pressure to form envelope signals of the first photoplethysmography PPG signals;
Determining a first blood pressure of the user from the envelope signal;
taking the first blood pressure as the blood pressure calibration information;
the processor is configured to:
the blood pressure calibration information is taken as a direct current component of the blood pressure of the user,
taking the initial blood pressure as an alternating component of the blood pressure of the user;
and calibrating the alternating current component of the blood pressure of the user according to the direct current component of the blood pressure of the user, and taking the calibrated blood pressure as the blood pressure of the user.
2. The blood pressure detection device of claim 1, wherein the processor is configured to:
driving a pressing module to press the first pressure to the user so as to form the first pressure;
controlling a first pulse wave detection module to detect the first photoplethysmography, PPG, signal when the first pressure acts on the user;
controlling a pressure detection module to detect the first pressure;
the first pressure and the first photoplethysmography PPG signal are received and the blood pressure calibration information is determined from the first pressure and the first photoplethysmography PPG signal.
3. The blood pressure detection device according to claim 2, characterized in that the blood pressure detection device further comprises: the pressure applying module is electrically connected with the processor, and the first pulse wave detecting module is electrically connected with the processor.
4. The blood pressure detection device of claim 1, wherein the processor is configured to:
the control prompt module outputs a prompt signal, and the prompt signal is used for prompting the user to apply pressure to the blood pressure detection device so as to form the first pressure;
controlling a first pulse wave detection module to detect the first photoplethysmography, PPG, signal when the first pressure acts on the user;
controlling a pressure detection module to detect the first pressure;
the first pressure and the first photoplethysmography PPG signal are received, and the blood pressure calibration information is determined according to the first pressure and the first photoplethysmography PPG signal.
5. The blood pressure detection device according to claim 4, further comprising: the prompting module is electrically connected with the processor, and the first pulse wave detection module is electrically connected with the processor.
6. The blood pressure detection device of claim 2 or 4, wherein the first pressure changes from large to small or from small to large over time.
7. The blood pressure detection device of any one of claims 1 to 5, wherein the processor is configured to:
Controlling a second pulse wave detection module to detect the second photoplethysmography, PPG, signal of the user;
and receiving the second photoplethysmography PPG signal, and processing the second photoplethysmography PPG signal by adopting a pulse wave analysis method or a pulse wave conduction time measurement method to obtain the initial blood pressure of the user.
8. The blood pressure detection device of claim 7, further comprising: the second pulse wave detection module is electrically connected with the processor.
9. The blood pressure detection device of any one of claims 1 to 5, wherein prior to the processor being configured to obtain the second photoplethysmography, PPG, signal, the processor is further configured to: determining whether the user is in a motion state;
if not, acquiring the second photoplethysmography (PPG) signal;
if so, after a preset time period, whether the user is in a motion state is determined again.
10. The blood pressure detection device of any one of claims 1 to 5, wherein the processor is configured to:
Acquiring the first photoplethysmography, PPG, signal at a first location of the user;
the second photoplethysmography, PPG, signal is acquired at a second location of the user, wherein the second location is different from the first location.
11. The blood pressure detection device of claim 10, wherein the first location is a finger of the user and the second location is a wrist of the user.
12. An electronic device, comprising:
the blood pressure detection device according to any one of claims 1 to 11.
13. The electronic device of claim 12, wherein the electronic device is a smart watch.
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