WO2023007810A1 - 測定用プローブ、カテーテルセットおよび測定システム - Google Patents

測定用プローブ、カテーテルセットおよび測定システム Download PDF

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Publication number
WO2023007810A1
WO2023007810A1 PCT/JP2022/010536 JP2022010536W WO2023007810A1 WO 2023007810 A1 WO2023007810 A1 WO 2023007810A1 JP 2022010536 W JP2022010536 W JP 2022010536W WO 2023007810 A1 WO2023007810 A1 WO 2023007810A1
Authority
WO
WIPO (PCT)
Prior art keywords
light
catheter
probe
fluid
measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2022/010536
Other languages
English (en)
French (fr)
Japanese (ja)
Inventor
賢志 澤田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Priority to JP2023538243A priority Critical patent/JP7750964B2/ja
Publication of WO2023007810A1 publication Critical patent/WO2023007810A1/ja
Priority to US18/417,119 priority patent/US20240156383A1/en
Anticipated expiration legal-status Critical
Priority to JP2025159391A priority patent/JP2025182014A/ja
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/201—Assessing renal or kidney functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/207—Sensing devices adapted to collect urine
    • A61B5/208—Sensing devices adapted to collect urine adapted to determine urine quantity, e.g. flow, volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6874—Bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0462—Apparatus with built-in sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04—Arrangements of multiple sensors of the same type
    • A61B2562/043—Arrangements of multiple sensors of the same type in a linear array
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/18—Shielding or protection of sensors from environmental influences, e.g. protection from mechanical damage
    • A61B2562/185—Optical shielding, e.g. baffles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
    • A61B5/02154—Measuring pressure in heart or blood vessels by means inserted into the body by optical transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH

Definitions

  • the retaining lid 215 is loosened. Through holes provided in the holding lid 215 , the holding rubber 214 , and the holding tube 213 communicate with the second pipe line 212 .
  • the holding rubber 214 is compressed and expands in the radial direction.
  • the swollen holding rubber 214 presses and fixes the side surface of the measurement probe 14 .
  • the holding rubber 214 realizes the function of the fixing section of the present embodiment, which can fix the measurement probe 14 inserted into the urinary tract 156 at an arbitrary position.
  • An index field 67, a date and time field 61, an oxygen partial pressure field 62, a temperature field 63 and a graph field 68 are displayed on the screen.
  • the index column 67 displays indices representing the state of the kidney. The user can easily grasp the patient's kidney condition by combining the alphabet and the symbol "+" or "-".
  • FIG. 22C shows the timing at which the optical analyzer 52 operates.
  • cj indicates the operation of analyzing the characteristics of the fluorescence emitted by the phosphor J; ck indicates the operation of analyzing the properties of the fluorescence emitted by the phosphor J; OFF indicates an operation in which fluorescence characteristics are not analyzed.
  • the horizontal axes in FIGS. 22A to 22C all indicate time.
  • the measurement probe 14 is inserted through the probe channel 157 having a diameter smaller than that of the urinary tract 156, even if the shape of the shaft 153 changes, the tip of the measurement probe 14 can be There is little positional change with the tip of the bladder indwelling catheter 15 . Therefore, it is possible to provide the measurement system 10 in which the measurement probe 14 is less likely to be pressed against the distal end side of the indwelling bladder catheter 15 even if the patient's posture changes.
  • the light emitter ring 245 is attached so that the light emitter 24 faces the urine funnel 154 side. As shown in FIG. 32B, emitter 24 blocks the end of probe conduit 157 .
  • the light emitter block 246 is formed by bending an optical fiber bundle into a U shape, for example.
  • Light emitter block 246 may be a combination of multiple optical components, such as light guides and prisms.
  • FIG. 48A is a cross-sectional view of the measurement probe 14 with the adapter 43 attached.
  • 48B is a cross-sectional view of adapter 43.
  • FIG. 48A and 48B are diagrams schematically showing configurations of the measurement probe 14 and the adapter 43 by reducing the longitudinal dimension of the measurement probe 14.
  • FIG. 48A and 48B are diagrams schematically showing configurations of the measurement probe 14 and the adapter 43 by reducing the longitudinal dimension of the measurement probe 14.
  • 49 and 50 are explanatory diagrams explaining how to use the measurement system 10 of the eighth embodiment.
  • An extension fiber 42 is connected to the measuring device 30 .
  • An optical fiber receptacle 421 is provided at one end of the extension fiber 42 .
  • the adapter 43 desirably has a lock mechanism for fixing the inner cylinder 435 in a state of being housed in the outer cylinder 436 . Note that the adapter 43 has flexibility similar to that of the urine collection tube 172 even when the inner cylinder 435 is accommodated inside the outer cylinder 436 while the measurement probe 14 is inserted.
  • FIG. 55 is a functional block diagram of measurement system 10 according to the tenth embodiment.
  • Measurement system 10 includes measurement probe 14 and measurement device 30 .
  • the measurement probe 14 includes a long body 41 that can be inserted into the catheter 15 having the flow path 156, a sensor 24 that is fixed to the long body 41 and capable of detecting the state of the fluid flowing through the flow path 156, and a long body. and a sensor holding portion 141 that holds the sensor 24 at a predetermined position when the scale body 41 is inserted into the catheter 15 .
  • the measuring device 30 includes a data acquisition unit 81 that acquires data from the sensor 24 held by the sensor holding unit 141, a determination unit 82 that determines the state of the patient in which the catheter 15 is indwelled based on the acquired data, and a determination unit 82. and a display unit 83 for displaying the state of the display.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Anesthesiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Optics & Photonics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
PCT/JP2022/010536 2021-07-30 2022-03-10 測定用プローブ、カテーテルセットおよび測定システム Ceased WO2023007810A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2023538243A JP7750964B2 (ja) 2021-07-30 2022-03-10 測定用プローブおよび測定システム
US18/417,119 US20240156383A1 (en) 2021-07-30 2024-01-19 Measurement probe, catheter set, and measurement system
JP2025159391A JP2025182014A (ja) 2021-07-30 2025-09-25 カテーテルセットおよび測定システム

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021126085 2021-07-30
JP2021-126085 2021-07-30

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US18/417,119 Continuation US20240156383A1 (en) 2021-07-30 2024-01-19 Measurement probe, catheter set, and measurement system

Publications (1)

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WO2023007810A1 true WO2023007810A1 (ja) 2023-02-02

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PCT/JP2022/010536 Ceased WO2023007810A1 (ja) 2021-07-30 2022-03-10 測定用プローブ、カテーテルセットおよび測定システム

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US (1) US20240156383A1 (https=)
JP (2) JP7750964B2 (https=)
WO (1) WO2023007810A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2022209703A1 (https=) * 2021-03-31 2022-10-06
WO2025142882A1 (ja) * 2023-12-25 2025-07-03 テルモ株式会社 尿の電気特性測定装置、尿の電気特性測定システム及び尿の電気特性測定方法

Families Citing this family (4)

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Publication number Priority date Publication date Assignee Title
CN216675721U (zh) 2020-08-03 2022-06-07 巴德阿克塞斯系统股份有限公司 布拉格光栅光纤波动感测与监测系统
US12426818B2 (en) 2022-06-08 2025-09-30 Bright Uro, Inc. Packaging assembly and method of preparing sensing device for insertion into a body cavity to preserve sterility
AU2023284982A1 (en) 2022-06-08 2025-01-09 Bright Uro, Inc. Systems and methods for urological sensing
US20260047765A1 (en) * 2024-08-19 2026-02-19 Bard Access Systems, Inc. Fiber Optics Thermometry System for Detection and Confirmation

Citations (4)

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Publication number Priority date Publication date Assignee Title
JP2016531650A (ja) * 2013-06-27 2016-10-13 セラノーヴァ，エルエルシー 感知フォーリー・カテーテル
WO2017033826A1 (ja) * 2015-08-24 2017-03-02 テルモ株式会社 カテーテル
WO2017213237A1 (ja) * 2016-06-10 2017-12-14 テルモ株式会社 酸素測定デバイス
WO2018180426A1 (ja) * 2017-03-30 2018-10-04 テルモ株式会社 モニタリングシステム及び酸素測定システム

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JP4388180B2 (ja) * 1999-11-08 2009-12-24 川澄化学工業株式会社 レーザーファイバーの誘導カテーテル
CH708172B1 (de) * 2013-05-30 2021-02-15 Unisensor Ag Sphincterprüfkatheter.
JP6333909B2 (ja) * 2016-09-15 2018-05-30 浜松ホトニクス株式会社 カテーテル
WO2020115843A1 (ja) * 2018-12-05 2020-06-11 オリンパス株式会社 光照射処置具

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016531650A (ja) * 2013-06-27 2016-10-13 セラノーヴァ，エルエルシー 感知フォーリー・カテーテル
WO2017033826A1 (ja) * 2015-08-24 2017-03-02 テルモ株式会社 カテーテル
WO2017213237A1 (ja) * 2016-06-10 2017-12-14 テルモ株式会社 酸素測定デバイス
WO2018180426A1 (ja) * 2017-03-30 2018-10-04 テルモ株式会社 モニタリングシステム及び酸素測定システム

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2022209703A1 (https=) * 2021-03-31 2022-10-06
WO2025142882A1 (ja) * 2023-12-25 2025-07-03 テルモ株式会社 尿の電気特性測定装置、尿の電気特性測定システム及び尿の電気特性測定方法

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US20240156383A1 (en) 2024-05-16
JP2025182014A (ja) 2025-12-11
JP7750964B2 (ja) 2025-10-07
JPWO2023007810A1 (https=) 2023-02-02

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