WO2022255978A1 - A composition against genital odors - Google Patents
A composition against genital odors Download PDFInfo
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- WO2022255978A1 WO2022255978A1 PCT/TR2022/050501 TR2022050501W WO2022255978A1 WO 2022255978 A1 WO2022255978 A1 WO 2022255978A1 TR 2022050501 W TR2022050501 W TR 2022050501W WO 2022255978 A1 WO2022255978 A1 WO 2022255978A1
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- composition according
- composition
- tocopherol
- genital
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 41
- 235000019645 odor Nutrition 0.000 title claims abstract description 34
- 210000004392 genitalia Anatomy 0.000 title claims abstract description 26
- 230000015572 biosynthetic process Effects 0.000 claims abstract description 12
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 18
- 241000186660 Lactobacillus Species 0.000 claims description 15
- 229940039696 lactobacillus Drugs 0.000 claims description 11
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 9
- 241000186000 Bifidobacterium Species 0.000 claims description 9
- 229920002674 hyaluronan Polymers 0.000 claims description 9
- 229960003160 hyaluronic acid Drugs 0.000 claims description 9
- 235000014655 lactic acid Nutrition 0.000 claims description 9
- 239000004310 lactic acid Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 9
- 239000002304 perfume Substances 0.000 claims description 9
- 229940043375 1,5-pentanediol Drugs 0.000 claims description 8
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 8
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- 244000068988 Glycine max Species 0.000 claims description 8
- 235000010469 Glycine max Nutrition 0.000 claims description 8
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 claims description 8
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 claims description 8
- 229930006000 Sucrose Natural products 0.000 claims description 8
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 8
- 235000010385 ascorbyl palmitate Nutrition 0.000 claims description 8
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 8
- 239000000706 filtrate Substances 0.000 claims description 8
- 239000000787 lecithin Substances 0.000 claims description 8
- 235000010445 lecithin Nutrition 0.000 claims description 8
- 229940067606 lecithin Drugs 0.000 claims description 8
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 8
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims description 8
- 239000005720 sucrose Substances 0.000 claims description 8
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims description 8
- 235000010384 tocopherol Nutrition 0.000 claims description 8
- 229960001295 tocopherol Drugs 0.000 claims description 8
- 229930003799 tocopherol Natural products 0.000 claims description 8
- 239000011732 tocopherol Substances 0.000 claims description 8
- 229940042585 tocopherol acetate Drugs 0.000 claims description 8
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 8
- 239000000047 product Substances 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 235000011187 glycerol Nutrition 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 239000013522 chelant Substances 0.000 claims description 3
- 238000000265 homogenisation Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 230000002335 preservative effect Effects 0.000 claims description 3
- 239000012467 final product Substances 0.000 claims description 2
- 239000007921 spray Substances 0.000 claims description 2
- 208000015181 infectious disease Diseases 0.000 description 8
- 241000894006 Bacteria Species 0.000 description 6
- 210000001215 vagina Anatomy 0.000 description 5
- 238000004140 cleaning Methods 0.000 description 4
- 206010046935 Vaginal odour Diseases 0.000 description 3
- 239000002453 shampoo Substances 0.000 description 3
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 229910052796 boron Inorganic materials 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000002906 microbiologic effect Effects 0.000 description 2
- 210000003899 penis Anatomy 0.000 description 2
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 229920000715 Mucilage Polymers 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 239000005844 Thymol Substances 0.000 description 1
- 206010046914 Vaginal infection Diseases 0.000 description 1
- 206010047786 Vulvovaginal discomfort Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- 229930008380 camphor Natural products 0.000 description 1
- HHTWOMMSBMNRKP-UHFFFAOYSA-N carvacrol Natural products CC(=C)C1=CC=C(C)C(O)=C1 HHTWOMMSBMNRKP-UHFFFAOYSA-N 0.000 description 1
- RECUKUPTGUEGMW-UHFFFAOYSA-N carvacrol Chemical compound CC(C)C1=CC=C(C)C(O)=C1 RECUKUPTGUEGMW-UHFFFAOYSA-N 0.000 description 1
- 235000007746 carvacrol Nutrition 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 241000902900 cellular organisms Species 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 239000011538 cleaning material Substances 0.000 description 1
- 210000003029 clitoris Anatomy 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 230000009986 erectile function Effects 0.000 description 1
- KSEBMYQBYZTDHS-HWKANZROSA-N ferulic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-N 0.000 description 1
- 229940114124 ferulic acid Drugs 0.000 description 1
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 description 1
- 235000001785 ferulic acid Nutrition 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- 208000000509 infertility Diseases 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 231100000535 infertility Toxicity 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- WYXXLXHHWYNKJF-UHFFFAOYSA-N isocarvacrol Natural products CC(C)C1=CC=C(O)C(C)=C1 WYXXLXHHWYNKJF-UHFFFAOYSA-N 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 231100001078 no known side-effect Toxicity 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 210000002640 perineum Anatomy 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000006041 probiotic Substances 0.000 description 1
- 230000000529 probiotic effect Effects 0.000 description 1
- 235000018291 probiotics Nutrition 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 210000004706 scrotum Anatomy 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229960000790 thymol Drugs 0.000 description 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 210000003905 vulva Anatomy 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
Definitions
- the invention relates to a composition used for eliminating genital odors and preventing odor formation.
- the invention also relates to a production method of a composition used to remove genital odors and prevent odor formation.
- the 'lactobacilli' group bacteria that should be present in the vagina take the sugar in the blood, break it down and turn it into lactic acid.
- the smell of lactic acid, which occurs due to the sugar breakdown process by lactobacilli, is also called genital odor.
- the PH value of this acid is called the vaginal acidic value and the normal is considered to be 4.
- the pH value is related to the lactobacilli in the genital area. Lack of lactobacilli means problems in the genital area.
- the beneficial bacteria in the genital area are called flora or biota. These bacteria also play a disinfectant and antiseptic role.
- a strong odor often described as a spoiled fishy odor, when there are bacterial infections. The second of these reasons suggests infection. Diagnosis and treatment must be done correctly. Because if infections are not treated on time, they are not limited to the vagina; It can cause problems leading to infertility by going to the cervix, uterus and tubes. It is not always necessary to accept the discharge and odor as normal. For this reason, it is appropriate for every woman to know her own vaginal odor and to consult her doctor when she suspects unnatural odors.
- vaginal cleaning In order not to experience vaginal odor or to suffer from vaginal discomfort. It is the external genital area called 'vulva', which is recommended to be cleaned under normal conditions. Cleaning the interior is not recommended. It is not healthy to wash because it is the bacterial wall that protects that area. On the contrary, it is harmful. However, if the woman and man have a polygamous life, it may be necessary to disinfect the vagina. One of the precautions to be taken here is the use of condoms. However, if you have an infection, a doctor should be consulted without delay. Unusual odor and discharge should be mentioned and the necessary diagnosis and treatment should be applied. If vaginal cleaning is recommended, special solutions can be used to prevent vaginal odor and infection with the advice of a doctor.
- Pantyhose tights and stretch jeans along with underwear can cause bacteria to grow. Because the area called 'perineum' where the vagina is, is already a dark area where humidity and temperature are high. Humidity, heat and darkness are a favorite environment for bacteria called microorganisms. Genital odors that come with infection can be prevented with simple precautions.
- Nylon synthetic underwear does not breathe. Hence, it is more prone to infections.
- thong type threaded underwear which is frequently worn in the modern world, is not a suitable choice for people who have an infection. It is recommended that women wear classic type underwear. Apart from these classical precautions, in the current technique, only cleaners that keep the pH levels low are used to prevent odor in the genital areas.
- the invention consists of a plant extract containing saponin and/or ferulic acid and/or mucilage, vegetable oil containing phytosterol and/or liposomal phospholipid and/or antioxidant, essential vegetable oil containing phenol and/or carvacrol and/or thymol and/or camphor, shampoo base, pH adjuster, emulsifier, gelling agent, thickening agent, wetting agent, preservative agent, scenting essence and/or essence mixture.” statements are included.
- a PH-adjusting herbal external genital area shampoo is disclosed.
- the present invention provides methods and compositions for the oral administration of other probiotic organisms such as Lactobacillus and/or Bifidobacteria for establishment and maintenance of a healthy urogenital flora.
- the invention also provides methods and compositions for reducing the risk of disease.
- the invention also provides probes for the detection of lactobacillus in biological samples.” statements are included.
- oral administration of lactobacillus for the prevention and treatment of urogenital infections is disclosed.
- the aim of the invention is to present a new composition for eliminating genital odors and preventing odor formation.
- Another object of the invention is to provide a composition that allows the removal of genital odors.
- Another object of the invention is to provide a composition that inhibits yeast (fungus) and/or bacteria that cause odor formation.
- Another object of the invention is to provide a composition that allows the pH level to be maintained at 5.5.
- Another object of the invention is to provide a composition that allows the genital area to be moistened.
- Another object of the invention is to provide a composition without side effects.
- Another aim of the invention is to present a composition developed in accordance with the intimate area, thanks to its skin-friendly postbiotic and liposomal active content, which is unique in terms of being a postbiotic and liposomal perfume.
- Another aim of the invention is to present a composition that gives confidence to the person thanks to its pleasant and lasting scent.
- Another object of the invention is to present a composition that helps maintain the moisture balance in the outer region of the intima, thanks to Liposomal Hyaluronic acid.
- the invention is a composition used to eliminate genital odors and prevent odor formation, characterized in that; comprises 7.70 - 7.82 grams of Lecithin, 0.06 - 0.10 grams Tocopherol, 0.3 -0.5 grams Tocopherol Acetate, 1.3 - 1.7 grams of Bifidobacterium/Lactobacillus/ Soybean/Sucrose Ferment Filtrate, 0.05 - 0.15 grams of Lactic Acid, 3,5 - 4.5 grams of Perfume, 0.015 - 0.025 grams of Hyaluronic acid, 0.06- 0.10 grams phosphatidylcholine, 0.000075 - 0.000085 grams of ascorbyl palmitate, 0.15 - 0.25 grams Pentylene Glycol and 0.05 - 0.15 grams tetrasodium EDTA.
- the invention is a composition production method used to eliminate genital odors and prevent odor formation, characterized in that; including method steps of homogenizing for 25 minutes in 3,5 - 4.5 grams of perfume, at 25°C, 7.70 - 7.82 grams of Lecithin and 0.06 - 0.10 grams of phosphatidylcholine, 0.15 - 0.25 grams of Pentylene Glycol is added and homogenization is continued for another 15 minutes for chelate formation, adding 0.05 - 0.15 grams of tetrasodium EDTA as a preservative, adding 0.3 - 0.5 grams of Tocopherol Acetate, 0.06 - 0.10 grams of Tocopherol and 0.000075 - 0.000085 grams of ascorbyl palmitate together with pure water, transferring the homogenized product for another 10 minutes to the mechanical mixer, mixing in a mechanical mixer by adding 0.015 - 0.025 grams of Hyaluronic acid and 1.3 - 1.7 grams of Bifidobacterium/
- Composition subject to the invention 7.70 - 7.82 grams of Lecithin, 0.06 - 0.10 grams of Tocopherol, 0.3 -0.5 grams of Tocopherol Acetate, 1.3 - 1.7 grams of Bifidobacterium/Lactobacillus/ Soybean /Sucrose Ferment Filtrate, 0.05 - 0.15 grams Lactic Acid, 3.5 -4.5 grams Perfume, 0.015 -0.025 grams Hyaluronic acid, 0.06-0.10 grams phosphatidylcholine, 0.000075 - 0.000085 gram ascorbyl palmitate, 0.03 - 0.05 gram glycerin, 0.15 - 0.25 gram Pentylene Glycol and 0.05 - 0.15 gram tetrasodium EDTA main elements.
- composition that is the subject of the invention, 3.5 - 4.5 grams of perfume are homogenized at 25°C in 7.70-7.82 grams of Lecithin and 0.06-0.10 grams of phosphatidylcholine for 25 minutes.
- 0.15 - 0.25 grams of Pentylene Glycol is added and homogenization is continued for another 15 minutes.
- 0.05 - 0.15 grams of tetrasodium EDTA is added at this stage.
- the product which is homogenized for 10 more minutes by adding 0.3 - 0.5 grams of Tocopherol Acetate, 0.06 - 0.10 grams of Tocopherol and 0.000075 - 0.000085 grams of ascorbyl palmitate together with pure water, is transferred to the mechanical mixer.
- the mixing process is started and 0.015 - 0.025 grams of Hyaluronic acid and 1.3 - 1.7 grams of Bifidobacterium/Lactobacillus/ Soybean/Sucrose Ferment Filtrate are added and mixed.
- the pH is adjusted between 4.2-4.5 with the help of 0.05 - 0.15 grams of Lactic Acid.
- the final product is filled into amber spray bottles and analyzed for quality index.
- the quality of the product is controlled by microbiological compatibility tests and physical analysis. Protecting the product from excessive light and high temperature will prevent shortening of its shelf life.
- the product can be used at temperatures up to +45 C, and there is a possibility of damage at temperatures above 45 C.
Abstract
The invention relates to a composition used for eliminating genital odors and preventing odor formation.
Description
A COMPOSITION AGAINST GENITAL ODORS
Technical Field
The invention relates to a composition used for eliminating genital odors and preventing odor formation.
The invention also relates to a production method of a composition used to remove genital odors and prevent odor formation.
Background of the Invention
The 'lactobacilli' group bacteria that should be present in the vagina take the sugar in the blood, break it down and turn it into lactic acid. The smell of lactic acid, which occurs due to the sugar breakdown process by lactobacilli, is also called genital odor.
The PH value of this acid is called the vaginal acidic value and the normal is considered to be 4. The pH value is related to the lactobacilli in the genital area. Lack of lactobacilli means problems in the genital area. The beneficial bacteria in the genital area are called flora or biota. These bacteria also play a disinfectant and antiseptic role.
Bad odor can affect every aspect of a woman's life. Apart from the physiological odor, there may be enough odor to disturb itself and sometimes even the environment. There are two reasons for these odors:
• The odor due to different chemical substances that come out of the blood at the time of bleeding.
• A strong odor, often described as a spoiled fishy odor, when there are bacterial infections.
The second of these reasons suggests infection. Diagnosis and treatment must be done correctly. Because if infections are not treated on time, they are not limited to the vagina; It can cause problems leading to infertility by going to the cervix, uterus and tubes. It is not always necessary to accept the discharge and odor as normal. For this reason, it is appropriate for every woman to know her own vaginal odor and to consult her doctor when she suspects unnatural odors.
There are some issues that women should pay attention to in genital cleaning in order not to experience vaginal odor or to suffer from vaginal discomfort. It is the external genital area called 'vulva', which is recommended to be cleaned under normal conditions. Cleaning the interior is not recommended. It is not healthy to wash because it is the bacterial wall that protects that area. On the contrary, it is harmful. However, if the woman and man have a polygamous life, it may be necessary to disinfect the vagina. One of the precautions to be taken here is the use of condoms. However, if you have an infection, a doctor should be consulted without delay. Unusual odor and discharge should be mentioned and the necessary diagnosis and treatment should be applied. If vaginal cleaning is recommended, special solutions can be used to prevent vaginal odor and infection with the advice of a doctor.
Pantyhose, tights and stretch jeans along with underwear can cause bacteria to grow. Because the area called 'perineum' where the vagina is, is already a dark area where humidity and temperature are high. Humidity, heat and darkness are a favorite environment for bacteria called microorganisms. Genital odors that come with infection can be prevented with simple precautions.
• Tight underwear and clothes should be worn as little as possible. It should be taken off at the first opportunity when you go home when it is worn.
• It would be appropriate to remove the tights at the first opportunity. In fact, women with very frequent infections may be advised to cut the net in the middle.
• Nylon synthetic underwear does not breathe. Hence, it is more prone to infections. Preferred are cotton underwear. Again, thong type threaded underwear, which is frequently worn in the modern world, is not a suitable choice for people who have an infection. It is recommended that women wear classic type underwear.
Apart from these classical precautions, in the current technique, only cleaners that keep the pH levels low are used to prevent odor in the genital areas.
In the patent application with the publication number TR 2021 003621 in the literature, “This invention is a genital area cleaning material consisting of a mixture of different forms of boron minerals in different densities and forms and water in various proportions, and the absorption of this mixture into synthetic or natural textile material/paper derivatives." statements are included. In said application, a boron-containing composition is disclosed for use in cleaning the genital area.
In the literature, in the patent application with the publication number TR 200603917, “An antimicrobial, which can be used before and after sexual intercourse, stimulates erectile functions by increasing blood circulation in the penis and clitoris regions, when applied to the external genital areas, including the penis and scrotum in men, and the vagina, lip and periphery in women. It relates to an external genital area shampoo with a slippery gel and herbal content. The invention consists of a plant extract containing saponin and/or ferulic acid and/or mucilage, vegetable oil containing phytosterol and/or liposomal phospholipid and/or antioxidant, essential vegetable oil containing phenol and/or carvacrol and/or thymol and/or camphor, shampoo base, pH adjuster, emulsifier, gelling agent, thickening agent, wetting agent, preservative agent, scenting essence and/or essence mixture.” statements are included. In the aforementioned application, a PH-adjusting herbal external genital area shampoo is disclosed.
Regarding the subject in PCT application publication number WO 2000/034710 in the literature, “The present invention provides methods and compositions for the oral administration of other probiotic organisms such as Lactobacillus and/or Bifidobacteria for establishment and maintenance of a healthy urogenital flora. The invention also provides methods and compositions for reducing the risk of disease. The invention also provides probes for the detection of lactobacillus in biological samples.” statements are included.
In the mentioned application, oral administration of lactobacillus for the prevention and treatment of urogenital infections is disclosed.
For the reasons mentioned above, there was a need to introduce a new composition to eliminate genital odors and prevent odor formation.
Disclosure of the Invention
Based on this position of the technique, the aim of the invention is to present a new composition for eliminating genital odors and preventing odor formation.
Another object of the invention is to provide a composition that allows the removal of genital odors.
Another object of the invention is to provide a composition that inhibits yeast (fungus) and/or bacteria that cause odor formation.
Another object of the invention is to provide a composition that allows the pH level to be maintained at 5.5.
Another object of the invention is to provide a composition that allows the genital area to be moistened.
Another object of the invention is to provide a composition without side effects.
Another aim of the invention is to present a composition developed in accordance with the intimate area, thanks to its skin-friendly postbiotic and liposomal active content, which is unique in terms of being a postbiotic and liposomal perfume.
Another aim of the invention is to present a composition that gives confidence to the person thanks to its pleasant and lasting scent.
Another object of the invention is to present a composition that helps maintain the moisture balance in the outer region of the intima, thanks to Liposomal Hyaluronic acid.
Detailed Description of the Invention
In this detailed explanation, the innovation that is the subject of the invention is only explained with examples that will not have any limiting effect for a better understanding of the subject. The invention is a composition used to eliminate genital odors and prevent odor formation, characterized in that; comprises 7.70 - 7.82 grams of Lecithin, 0.06 - 0.10 grams Tocopherol, 0.3 -0.5 grams Tocopherol Acetate, 1.3 - 1.7 grams of Bifidobacterium/Lactobacillus/ Soybean/Sucrose Ferment Filtrate, 0.05 - 0.15 grams of Lactic Acid, 3,5 - 4.5 grams of Perfume, 0.015 - 0.025 grams of Hyaluronic acid, 0.06- 0.10 grams phosphatidylcholine, 0.000075 - 0.000085 grams of ascorbyl palmitate, 0.15 - 0.25 grams Pentylene Glycol and 0.05 - 0.15 grams tetrasodium EDTA.
At the same time, the invention is a composition production method used to eliminate genital odors and prevent odor formation, characterized in that; including method steps of homogenizing for 25 minutes in 3,5 - 4.5 grams of perfume, at 25°C, 7.70 - 7.82 grams of Lecithin and 0.06 - 0.10 grams of phosphatidylcholine, 0.15 - 0.25 grams of Pentylene Glycol is added and homogenization is continued for another 15 minutes for chelate formation, adding 0.05 - 0.15 grams of tetrasodium EDTA as a preservative, adding 0.3 - 0.5 grams of Tocopherol Acetate, 0.06 - 0.10 grams of Tocopherol and 0.000075 - 0.000085 grams of ascorbyl palmitate together with pure water, transferring the homogenized product for another 10 minutes to the mechanical mixer, mixing in a mechanical mixer by adding 0.015 - 0.025 grams of Hyaluronic acid and 1.3 - 1.7 grams of Bifidobacterium/Lactobacillus/ Soybean/Sucrose Ferment Filtrate.
Composition subject to the invention, 7.70 - 7.82 grams of Lecithin, 0.06 - 0.10 grams of Tocopherol, 0.3 -0.5 grams of Tocopherol Acetate, 1.3 - 1.7 grams of Bifidobacterium/Lactobacillus/ Soybean /Sucrose Ferment Filtrate, 0.05 - 0.15 grams Lactic Acid, 3.5 -4.5 grams Perfume, 0.015 -0.025 grams Hyaluronic acid, 0.06-0.10
grams phosphatidylcholine, 0.000075 - 0.000085 gram ascorbyl palmitate, 0.03 - 0.05 gram glycerin, 0.15 - 0.25 gram Pentylene Glycol and 0.05 - 0.15 gram tetrasodium EDTA main elements. In the composition that is the subject of the invention, 3.5 - 4.5 grams of perfume are homogenized at 25°C in 7.70-7.82 grams of Lecithin and 0.06-0.10 grams of phosphatidylcholine for 25 minutes. In order to form a chelate, 0.15 - 0.25 grams of Pentylene Glycol is added and homogenization is continued for another 15 minutes. As a preservative, 0.05 - 0.15 grams of tetrasodium EDTA is added at this stage. The product, which is homogenized for 10 more minutes by adding 0.3 - 0.5 grams of Tocopherol Acetate, 0.06 - 0.10 grams of Tocopherol and 0.000075 - 0.000085 grams of ascorbyl palmitate together with pure water, is transferred to the mechanical mixer. The mixing process is started and 0.015 - 0.025 grams of Hyaluronic acid and 1.3 - 1.7 grams of Bifidobacterium/Lactobacillus/ Soybean/Sucrose Ferment Filtrate are added and mixed.
The pH is adjusted between 4.2-4.5 with the help of 0.05 - 0.15 grams of Lactic Acid. The final product is filled into amber spray bottles and analyzed for quality index.
Before the filled bottles are packed, the quality of the product is controlled by microbiological compatibility tests and physical analysis. Protecting the product from excessive light and high temperature will prevent shortening of its shelf life. The product can be used at temperatures up to +45 C, and there is a possibility of damage at temperatures above 45 C.
It is foreseen that individuals who are allergic to any ingredient contained in the invention should not use it. It has no known side effects. It can be consumed by applying 3-4 times a day.
It is necessary to comply with the hygiene conditions during production and to package the products that pass the microbiological compatibility tests.
In the preferred application of the invention, 7.76 grams of Lecithin, 0.08 grams of Tocopherol, 0.4 grams of Tocopherol Acetate, 1.5 grams of Bifidobacterium/Lactobacillus/ Soybean/Sucrose Ferment Filtrate, 0.1 grams of Lactic Acid, 4 grams of Perfume, 0 0.02 grams of Hyaluronic acid, 0.08 grams of phosphatidylcholine, 0.00008 grams of ascorbyl palmitate, 0.04 grams of glycerin, 0.2 grams of Pentylene Glycol and 0.1 grams of tetrasodium EDTA are used.
Claims
1. The invention is a composition used to eliminate genital odors and prevent odor formation, characterized in that; comprises 7.70 - 7.82 grams of Lecithin, 0.06 - 0.10 grams Tocopherol, 0.3 -0.5 grams Tocopherol Acetate, 1.3 - 1.7 grams of Bifidobacterium/Lactobacillus/ Soybean/Sucrose Ferment Filtrate, 0.05 - 0.15 grams of Lactic Acid, 3,5 - 4.5 grams of Perfume, 0.015 - 0.025 grams of Hyaluronic acid, 0.06- 0.10 grams phosphatidylcholine, 0.000075 - 0.000085 grams of ascorbyl palmitate, 0.15 - 0.25 grams Pentylene Glycol and 0.05 - 0.15 grams tetrasodium EDTA.
2. A composition according to claim 1 ; it contains 0.03 - 0.05 grams of glycerin.
3. A composition according to any one of the above claims, it contains 7.76 grams of Lecithin.
4. A composition according to any one of the above claims, it contains 0.08 grams of Tocopherol.
5. A composition according to any one of the above claims, it contains 0.4 grams
Tocopherol Acetate.
6. A composition according to any one of the above claims, it contains 1.5 grams of Bifidobacterium/Lactobacillus/ Soybean/Sucrose Ferment Filtrate.
7. A composition according to any one of the above claims, it contains 0.1 grams of Lactic Acid.
8. A composition according to any one of the above claims, it contains 4 grams of Perfume.
9. A composition according to any one of the above claims, it contains 0.02 grams of Hyaluronic acid.
10. A composition according to any one of the above claims, it contains 0.08 grams of phosphatidylcholine.
11. A composition according to any one of the above claims, it contains 0.00008 grams of ascorbyl palmitate.
12. A composition according to any one of the above claims, it contains 0.04 grams of glycerine.
13. A composition according to any one of the above claims, it contains 0.2 grams of Pentylene Glycol.
14. A composition according to any one of the above claims, it contains; 0.1 gram of tetrasodium EDTA.
15. The invention is a composition production method used to eliminate genital odors and prevent odor formation, characterized in that; including method steps of homogenizing for 25 minutes in 3,5 - 4.5 grams of perfume, at 25°C, 7.70 - 7.82 grams of Lecithin and 0.06 - 0.10 grams of phosphatidylcholine, 0.15 - 0.25 grams of Pentylene Glycol is added and homogenization is continued for another 15 minutes for chelate formation, adding 0.05 - 0.15 grams of tetrasodium EDTA as a preservative, adding 0.3 - 0.5 grams of Tocopherol Acetate, 0.06 - 0.10 grams of Tocopherol and 0.000075 - 0.000085 grams of ascorbyl palmitate together with pure water, transferring the homogenized product for another 10 minutes to the mechanical mixer, mixing in a mechanical mixer by adding 0.015 - 0.025 grams of Hyaluronic acid and 1 .3 - 1 .7 grams of Bifidobacterium/Lactobacillus/ Soybean/Sucrose Ferment Filtrate.
16. lt is a composition production method in accordance with claim 15 and its feature is; It includes the method step of adjusting the pH between 0.05 - 0.15 grams with the help of Lactic Acid between 4.2-4.5 and filling the final product into amber spray bottles and performing quality index analysis.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TR2021008922 | 2021-05-31 | ||
TR2021/008922 TR2021008922A2 (en) | 2021-05-31 | A COMPOSITION AGAINST GENITAL ODORS AND A RELATED PRODUCTION METHOD |
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WO2022255978A1 true WO2022255978A1 (en) | 2022-12-08 |
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Application Number | Title | Priority Date | Filing Date |
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PCT/TR2022/050501 WO2022255978A1 (en) | 2021-05-31 | 2022-05-31 | A composition against genital odors |
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WO (1) | WO2022255978A1 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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US20080260869A1 (en) * | 2007-04-19 | 2008-10-23 | Mary Kay Inc. | Magnolia extract containing compositions |
US20110306577A1 (en) * | 2010-06-11 | 2011-12-15 | Perricone Nicholas V | Topical skin cream comprising phosphatidylcholine dha and l-tyrosine |
CN111905030A (en) * | 2019-05-09 | 2020-11-10 | 吉林正昇康生物工程有限公司 | Vagina health care gel and preparation method and application thereof |
-
2022
- 2022-05-31 WO PCT/TR2022/050501 patent/WO2022255978A1/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080260869A1 (en) * | 2007-04-19 | 2008-10-23 | Mary Kay Inc. | Magnolia extract containing compositions |
US20110306577A1 (en) * | 2010-06-11 | 2011-12-15 | Perricone Nicholas V | Topical skin cream comprising phosphatidylcholine dha and l-tyrosine |
CN111905030A (en) * | 2019-05-09 | 2020-11-10 | 吉林正昇康生物工程有限公司 | Vagina health care gel and preparation method and application thereof |
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