WO2022222414A1 - Blood sample cultivation and testing workstation - Google Patents

Blood sample cultivation and testing workstation Download PDF

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Publication number
WO2022222414A1
WO2022222414A1 PCT/CN2021/128027 CN2021128027W WO2022222414A1 WO 2022222414 A1 WO2022222414 A1 WO 2022222414A1 CN 2021128027 W CN2021128027 W CN 2021128027W WO 2022222414 A1 WO2022222414 A1 WO 2022222414A1
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WO
WIPO (PCT)
Prior art keywords
plate
blood
culture
blood sample
gripper
Prior art date
Application number
PCT/CN2021/128027
Other languages
French (fr)
Chinese (zh)
Inventor
林华青
李旭运
游少华
Original Assignee
珠海迪尔生物工程股份有限公司
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Publication date
Application filed by 珠海迪尔生物工程股份有限公司 filed Critical 珠海迪尔生物工程股份有限公司
Publication of WO2022222414A1 publication Critical patent/WO2022222414A1/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/48Holding appliances; Racks; Supports
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/52Mobile; Means for transporting the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control

Definitions

  • the invention relates to the technical field of medical equipment, in particular to a blood sample culture detection workstation.
  • Blood culture is the inoculation of blood obtained by venipuncture into one or more culture flasks or culture tubes to find and identify bacteria or other culturable and isolated microorganisms that exist in the blood to form bacteremia or fungal bacteremia disease.
  • the detection of microorganisms in the blood of patients has important clinical significance for the diagnosis, treatment and prognosis of infectious diseases.
  • Blood culture generally includes the following operations. The blood is inoculated into a culture bottle to form a blood sample, and then the culture bottle is placed on the culture institution. Move it into a plate, contact the drug sensitive paper with the blood sample, and confirm the effect of drug sensitivity detection by observing the color change of the drug sensitive paper.
  • the blood sample When transferring a blood sample, the blood sample is generally dropped or drawn into the plate by a suction device.
  • the blood sample cannot be filled with the plate, and the position of the drug sensitive paper in the plate cannot be fixed, which is easy to use.
  • the drug susceptibility paper is not stained with blood samples, which makes the drug susceptibility test impossible.
  • the present invention aims to solve at least one of the technical problems existing in the prior art. To this end, the present invention proposes a blood sample culture detection workstation, which can replace humans to complete blood culture and detection and improve efficiency.
  • a blood sample culture detection workstation includes a machine table, a blood-taking device for a plate, a drug-sensitive paper dispenser, a culture component, a detection device, and a handling device.
  • the machine table is provided with a bracket;
  • the plate blood taking device includes a culture bottle clamping claw, a blood sampling piece clamping claw and a first plate clamping claw all arranged on the bracket, the culture bottle clamping claw and the
  • the first plate gripper is set downward and upward respectively, and the culture bottle gripper, the blood collection piece gripper and the first dish gripper can be arranged in order from top to bottom;
  • the drug-sensitive paper The dispenser is arranged on the support, the drug-sensitive paper dispenser can face the first plate gripper, and the drug-sensitive paper dispenser is used to put the drug-sensitive paper into the plate;
  • the culture component and the The detection devices are all arranged on the machine table;
  • the handling device is arranged on the machine table, and the transportation device can place the plate on the first plate gripper or the culture component or the detection
  • the blood sample culture detection workstation has at least the following beneficial effects: the culture bottle clamping jaw, the blood sampling piece clamping claw and the first plate clamping claw respectively clamp the culture bottle, the blood sampling piece and the plate, and when the culture bottle is clamped
  • the jaws, the jaws of the blood collection piece and the jaws of the first plate are arranged in order from top to bottom, the blood collection piece can pierce the bottle cap of the culture bottle, and the blood sample in the culture bottle will fall into the plate.
  • the drug sensitive paper dispenser puts the drug sensitive paper into the plate, and then the transport device transports the plate on the first plate gripper into the culture component.
  • the transport device transfers the The plate is transported to the detection device, and the detection device observes the blood sample in the plate, observes the size and shape of the microorganisms in the blood sample and whether there is microbial growth near the drug sensitive paper, etc., to determine the type of microorganisms and obtain the results of drug sensitivity testing.
  • the blood sample culture detection workstation has a high degree of automation and can replace humans to complete blood culture and detection, which improves efficiency and reduces labor costs.
  • the bracket is provided with a first installation plate that moves in the front-rear direction, the first installation plate is connected with a second installation plate that moves in the left-right direction, and the first plate gripper It can be slid back and forth on the bracket, and the first plate gripper can be rotated.
  • the culture bottle gripper can be lifted up and down on the first mounting plate. Holding the inverted culture bottle, the first mounting plate can drive the culture bottle to be above the first plate gripper, the blood sampling piece gripper is connected with the second mounting plate, the second The mounting plate can drive the blood sampling piece to face the bottle opening of the culture bottle.
  • the bracket is further provided with a first forward and backward moving mechanism, the output end of the first forward and backward moving mechanism is connected with a stage, and the first plate gripper is rotatably connected to the on the stage.
  • the first plate gripper includes a carrier plate and two support plates, both of which are arranged on the carrier plate, and the carrier plate is rotatably arranged on the carrier plate.
  • first limit grooves are opened on the corresponding sides of the upper surfaces of the two support plates, the bottoms of the two first limit grooves can abut the bottom of the plate, and the two The side wall of the first limiting groove can abut against the side wall of the plate.
  • the first forward and backward moving mechanism includes a first linear drive mechanism, and a first sliding rail and a first sliding block cooperating with each other, the first sliding rail extending in the forward and backward direction and being connected with the The support is connected, the carrier is connected with the first sliding block, and the output end of the first linear drive mechanism is connected with the first sliding block or the carrier.
  • the bracket is provided with a cover opening mechanism in an area corresponding to the upper part of the first slide rail, and the cover opening mechanism includes a lifting block that can be raised and lowered, and a front side wall of the lifting block is provided with a cover opening mechanism.
  • the cover opening mechanism includes a lifting block that can be raised and lowered, and a front side wall of the lifting block is provided with a cover opening mechanism.
  • There is a first receiving groove for accommodating the plate the bottom of the first receiving groove is provided with a first escape groove into which the box body of the plate and the first plate jaw can extend, the first receiving groove The bottom wall of the plate can abut on the lower end surface of the lid of the plate.
  • the lid opening mechanism further includes a cam lifting mechanism and a second sliding rail and a second sliding block that cooperate with each other, the second sliding rail is provided on the machine table and is in an up-down direction extension, the lifting block is connected with the second sliding block, the cam lifting mechanism is arranged on the machine table, and the output end of the cam lifting mechanism is connected to the lifting block or the second sliding block Hinged.
  • the detection device includes a support frame disposed on the machine table and a camera module upwardly disposed on the support frame, and the support frame is above the camera module corresponding to the A support plate is arranged in the area of the plate, a second limit groove for limiting the plate is arranged on the support plate, and an observation hole is arranged at the bottom of the second limit groove.
  • the support plate is provided with a light source in a region corresponding to the peripheral side of the second limiting groove.
  • the conveying device includes a second forward-backward moving mechanism, a left-right moving mechanism, a second rotational driving mechanism, a lifting moving mechanism, and a second plate gripper, which are connected in sequence, and the second forward-backward moving mechanism is connected to The machine is connected.
  • FIG. 1 is a schematic structural diagram of a blood sample culture detection workstation according to an embodiment of the present invention
  • FIG. 2 is a schematic structural diagram of a plate blood sampling device in a blood sample culture detection workstation according to an embodiment of the present invention
  • Fig. 3 is the partial enlarged schematic diagram of A place in Fig. 2;
  • FIG. 4 is a schematic structural diagram of an opening mechanism in a blood sample culture detection workstation according to an embodiment of the present invention.
  • FIG. 5 is a schematic structural diagram of a detection device in a blood sample culture detection workstation according to an embodiment of the present invention.
  • FIG. 6 is a schematic structural diagram of a handling device in a blood sample culture detection workstation according to an embodiment of the present invention.
  • Machine table 100 bracket 110, second mounting plate 120, third slide rail 121, third slider 122, gear 123, rack 124, first forward and backward moving mechanism 130, first linear drive mechanism 131, first slide Rail 132, fourth slide rail 140, first mounting plate 150, elevating drive mechanism 151, third mounting plate 152, turning plate 160, second linear drive mechanism 170, plate blood sampling device 200, culture bottle gripper 210, Blood sample gripper 220, first plate gripper 230, carrier plate 231, support plate 232, drug sensitive paper dispenser 300, culture assembly 400, detection device 500, support frame 510, support plate 511, camera module 520, light source 530, conveying device 600, second forward and backward movement mechanism 610, left and right movement mechanism 620, second rotation drive mechanism 630, lift movement mechanism 640, second plate gripper 650, stage 700, first rotation drive mechanism 710, first The limiting slot 800 , the cover opening mechanism 900 , the lifting block 910 , the first receiving slot 911 , the cam lifting mechanism 920 , the second sliding rail 930
  • the meaning of several is one or more, the meaning of multiple is two or more, greater than, less than, exceeding, etc. are understood as not including this number, above, below, within, etc. are understood as including this number . If it is described that the first and the second are only for the purpose of distinguishing technical features, it cannot be understood as indicating or implying relative importance, or indicating the number of the indicated technical features or the order of the indicated technical features. relation.
  • the present invention discloses a blood sample culture detection workstation, including a machine 100 , a plate blood sampling device 200 , a drug sensitive paper dispenser 300 , a culture assembly 400 , a detection device 500 and a handling device 600 .
  • the machine table 100 is provided with a bracket 110;
  • the plate blood taking device 200 includes a culture bottle gripper 210, a blood sampling piece gripper 220 and a first plate gripper 230, which are all arranged on the support 110.
  • the culture bottle gripper 210 and the first plate gripper 230 The plate clamping jaws 230 are respectively set downward and upward, the culture bottle clamping jaw 210, the blood sampling piece clamping jaw 220 and the first plate clamping jaw 230 can be arranged in order from top to bottom; the drug sensitive paper dispenser 300 is arranged on the bracket On 110, the drug-sensitive paper dispenser 300 can face the first plate gripper 230, and the drug-sensitive paper dispenser 300 is used to put the drug-sensitive paper into the plate; the culture assembly 400 and the detection device 500 are both arranged on the machine 100;
  • the handling device 600 is disposed on the machine table 100 , and the handling device 600 can place the plate on the first plate gripper 230 or the culture assembly 400 or the detection device 500 .
  • the culture bottle gripper 210, the blood collection piece gripper 220 and the first plate gripper 230 respectively clamp the culture flask, the blood collection piece and the flat dish.
  • the culture bottle gripper 210, the blood collection piece gripper 220 and the first plate gripper When the 230 is set in order from top to bottom, the blood sampling piece can pierce the cap of the culture bottle, the blood sample in the culture bottle will fall into the plate, and then the drug sensitive paper dispenser 300 will put the drug sensitive paper into the plate, and then The transport device 600 transports the plate on the first plate gripper 230 into the culture assembly 400. After the blood sample is cultured in the culture assembly 400, the transport device 600 transports the plate in the culture assembly 400 to the detection device 500.
  • the detection device 500 Observing the blood samples in the plate, observing the size and shape of the microorganisms in the blood samples and whether there is microbial growth near the drug sensitive paper, etc., to determine the type of microorganisms and obtain the results of drug sensitivity testing.
  • the blood sample culture detection workstation has a high degree of automation and can replace humans to complete blood culture and detection, which improves efficiency and reduces labor costs.
  • the blood sampling piece is in the shape of a sleeve, and the blood sampling piece is provided with a needle.
  • the culture bottle gripper 210 When the culture bottle gripper 210 is lowered with the culture bottle, the blood sampling piece can be sleeved on the bottle mouth of the culture bottle, and the needle is The cap can be pierced through a small hole, and the blood sample can fall into the dish through the small hole.
  • the blood collection piece is a one-time item. After the blood collection piece is used once, the blood collection piece gripper 220 is discarded and replaced with a blood collection piece, and then a new blood collection piece is clamped by the blood collection piece gripper 220. blood collection.
  • the plate is a common transparent part, and the plate includes a box body and a lid.
  • the drug-sensitive paper dispenser 300 is also a common component, and the drug-sensitive paper is placed in the drug-sensitive paper dispenser 300, and the drug-sensitive paper dispenser 300 can release the drug-sensitive papers one by one.
  • the culture assembly 400 is a common incubator.
  • the bracket 110 is provided with a first mounting plate 150 that moves in the front-rear direction, the first mounting plate 150 is connected to a second mounting plate 120 that moves in the left-right direction, and the first plate gripper 230 can be
  • the first plate clamping jaw 230 is rotatable, and the culture bottle clamping jaw 210 can be lifted and lowered on the first mounting plate 150.
  • the culture bottle clamping jaw 210 is used for clamping the inverted culture bottle.
  • the first mounting plate 150 can drive the culture bottle gripper 210/the culture bottle to be above the first plate gripper 230, the blood sampling piece gripper 220 is connected with the second mounting plate 120, and the second mounting plate 120 can drive the blood sampling piece The clamping jaw 220/blood sampling piece is facing the bottle mouth of the culture bottle.
  • the first plate clamp 230 clamps the unused plate and fixes the position of the plate on the support 110, and the culture bottle clamp 210 clamps the culture bottle containing the blood sample, and the blood sample is collected.
  • the jaws 220 hold the blood sampling piece.
  • the first mounting plate 150 carries the culture bottle and the blood sampling piece to move in the front-rear direction, and the first plate gripper 230 drives the plate to rotate, which can finally make the mixing After the liquid falls into the plate, it is distributed in a spiral shape, that is, it is distributed in the plate in the form of mosquito coils. Since the blood samples are evenly distributed in the plate, it is ensured that the drug sensitive paper can be stained with the blood samples, so that the drug sensitivity test can be carried out smoothly, and it is avoided that some blood samples cannot be tested for drug sensitivity.
  • the actions of the blood sampling piece clamping jaw 220 and the culture bottle clamping claw 210 respectively holding the blood sampling piece and the culture bottle can be referred to as follows.
  • the second mounting plate 120 drives the blood sampling piece clamping claw 220 to move, so that the blood sampling piece clamping jaw 220 and the culture bottle are moved.
  • the bottle clamping jaws 210 are not on the same axis, so that it is convenient for the blood sampling piece clamping claw 220 and the culture bottle clamping claw 210 to clamp the blood sampling piece and the culture bottle respectively, so as to avoid mutual interference between the blood sampling piece clamping claw 220 and the culture bottle clamping claw 210;
  • the second mounting plate 120 drives the blood sampling piece clamping claw 220 to move, so that the blood sampling piece clamping claw 220 and the culture bottle clamping claw 210 on the same axis.
  • the first plate gripper 230 carries the plate and moves under the blood collection member gripper 220, so as to complete the preparation for transferring the blood sample into the plate.
  • the machine table 100 is further provided with a first forward and backward moving mechanism 130 , the output end of the first forward and backward moving mechanism 130 is connected with the carrier table 700 , and the first plate gripper 230 is rotatably connected to the carrier table 700 .
  • Taiwan 700 The first back-and-forth moving mechanism 130 drives the first plate gripper 230 to move in the front-rear direction through the stage 700, thereby completing the function of transporting dishes from other areas to a specific area, avoiding the culture bottle gripper 210 and the blood collection piece gripper 220 Interference with the first plate gripper 230 for loading the plate.
  • the first plate gripper 230 includes a carrier plate 231 and two support plates 232 .
  • the two support plates 232 are both disposed on the carrier plate 231 , and the carrier plate 231 is rotatably disposed on the carrier platform 700 .
  • the corresponding sides of the upper surfaces of the two support plates 232 are provided with first limiting grooves 800 , the bottoms of the two first limiting grooves 800 can abut the bottom of the plate, and the two first limiting grooves 800
  • the side wall may abut the side wall of the plate.
  • the bottom of the plate abuts on the bottom of the first limiting groove 800
  • the bottom of the first limiting groove 800 plays the role of supporting the plate
  • the side wall of the plate abuts against the bottom of the first limiting groove 800.
  • the side wall of the first limiting slot 800 serves to limit the movement of the plate in the horizontal direction.
  • the two support plates 232 are slidably disposed on the carrier plate 231, and the distance between the two support plates 232 can be adjusted, so that the combined space area of the two first limiting grooves 800 can be adjusted.
  • the first plate clamping jaws 230 can hold plates of different sizes.
  • the carrier 700 is provided with a first rotational drive mechanism 710 , the first plate gripper 230 can be connected to the carrier 700 through a bearing, and the first rotational drive mechanism 710 is connected to the carrier plate 231 by transmission.
  • the first rotation driving mechanism 710 drives the carrier plate 231 to rotate, thereby making the plate rotate.
  • the first plate clamping jaws 230 are disposed upward, so as to make the plate face upward.
  • the first rotary drive mechanism 710 is a second motor, the output end of the second motor is provided with a first transmission gear, the carrier plate 231 is provided with a second transmission gear that meshes with the first transmission gear, and the second motor is driven by the first transmission gear.
  • the gear and the second transmission gear drive the carrier plate 231 to rotate.
  • the first forward and backward moving mechanism 130 includes a first linear drive mechanism 131 and a first sliding rail 132 and a first sliding block that cooperate with each other.
  • the first sliding rail 132 extends in the front and rear direction and is connected to the machine table. 100 is connected, the carrier 700 is connected with the first slider, and the output end of the first linear drive mechanism 131 is connected with the first slider or the carrier 700, so that the first linear drive mechanism 131 can drive the carrier 700 in the first
  • the slide rail 132 moves in the front-rear direction.
  • the first linear drive mechanism 131 can be a second screw pair or a first electric cylinder or a first air cylinder.
  • the bracket 110 is provided with a cover opening mechanism 900 in the area corresponding to the upper part of the first slide rail 132 , and the cover opening mechanism 900 includes a lifting block 910 that can be lifted and lowered.
  • the first receiving groove 911 for accommodating the plate, the bottom of the first receiving groove 911 is provided with a first escape groove for the box body of the plate and the first plate jaw 230 to extend into, and the bottom wall of the first receiving groove 911 can abut against the plate. on the lower end of the lid of the dish.
  • the lifting block 910 When the lifting block 910 is in a low position, the first receiving groove 911 is at the same height as the plate on the first plate clamp 230, the first plate clamp 230 carries the plate to move, and the first plate clamp 230 and the plate can enter the first plate respectively. At this time, the lifting block 910 is driven to rise, the bottom wall of the first receiving groove 911 lifts the lid of the plate, the cover is temporarily stored on the lifting block 910, and the box of the plate is still in the first A plate clamping claw 230 is placed on the plate, thereby completing the opening of the plate.
  • the cover opening mechanism 900 further includes a cam jacking mechanism 920 and a second sliding rail 930 and a second sliding block 940 that cooperate with each other.
  • the second sliding rail 930 is provided on the machine table 100 and extends in the up-down direction.
  • the lifting block 910 is connected with the second sliding block 940, the cam lifting mechanism 920 is arranged on the machine table 100 and the output end of the cam lifting mechanism 920 is hinged with the lifting block 910 or the second sliding block 940, and the cam lifting mechanism 920 drives the lifting block 910 the lift.
  • the cam jacking mechanism 920 is a common component and has the advantages of easy control and simple structure.
  • the cam jacking mechanism 920 includes a connecting rod, a third motor disposed on the bracket 110 and a runner disposed on the output end of the third motor, one end of the connecting rod is hinged with the non-axis of the runner, and the connection is The other end of the rod is hinged with the lifting block 910 or the second sliding block 940 .
  • the bracket 110 is provided with a plate turning mechanism in the region corresponding to the upper part of the first sliding rail 132 .
  • the plate turning mechanism includes a rotating shaft rotatably arranged on the support 110 and a turning plate 160 arranged on the rotating shaft.
  • the turning plate 160 is provided with a second receiving slot for temporarily storing the plate. When the plate is placed in the second receiving slot Then, the turning plate 160 is rotated 180° around the axis of the rotating shaft, and the plate can be turned upside down.
  • the flip plate 160 is provided with a second avoidance groove communicating with the second storage groove, and the first plate clamping jaw 230 can extend into the second avoidance groove and remove the plate in the second storage groove.
  • the blood sampling device clamping jaw 220 is connected to the second mounting plate 120 through a third sliding rail 121 and a third sliding block 122 that cooperate with each other.
  • the third sliding rail 121 extends in the left-right direction, and the second mounting plate
  • a first motor is provided on the plate 120
  • a gear 123 is provided on the output end of the first motor
  • a rack 124 is provided on the third sliding block 122 or the blood sampling claw 220 which cooperates with the gear 123 .
  • the first motor drives the third sliding block 122/blood sampling claw 220 to move on the third sliding rail 121 through the gear 123 and the gear 123 .
  • the structures of the first motor, the gear 123 and the gear 123 are simple, easy to install and easy to control.
  • the first mounting plate 150 is connected to the bracket 110 through a fourth sliding block and a fourth sliding rail 140 that cooperate with each other, the fourth sliding rail 140 extends in the front-rear direction, and the first mounting plate 150 is provided with The elevating drive mechanism 151 and the elevating third mounting plate 152 , the culture bottle gripper 210 is connected to the first mounting plate 150 through the third mounting plate 152 , and the output end of the elevating drive mechanism 151 is connected to the third mounting plate 152 .
  • the first mounting plate 150 is facilitated to move in the front-rear direction on the bracket 110 through the fourth sliding block and the fourth sliding rail 140; the elevating driving mechanism 151 drives the third mounting plate 152 to ascend and descend, and the third mounting plate 152 carries the culture bottle clamps 210 lift.
  • the third mounting plate 152 is connected to the first mounting plate 150 through the matched fifth sliding block and fifth sliding rail.
  • the lift driving mechanism 151 can be a first screw pair or a second air cylinder or a second electric cylinder.
  • the bracket 110 is further provided with a second linear drive mechanism 170 , the output end of the second linear drive mechanism 170 is connected to the fourth slide rail 140 or the first mounting plate 150 , and the second linear drive mechanism 170
  • the fourth sliding rail 140/the first mounting plate 150 can be driven to be fixed on the bracket 110 in the front-rear direction.
  • the detection device 500 includes a support frame 510 disposed on the machine table 100 and a camera module 520 upwardly disposed on the support frame 510 .
  • the support frame 510 is provided with a support plate 511 in the area above the corresponding camera module 520 .
  • the support plate 511 is provided with a second limiting groove for limiting the plate, and the bottom of the second limiting groove is provided with an observation hole.
  • the conveying device 600 is transported into the second limit groove through the plate of microorganism culture, the second limit groove plays the role of limiting the plate, and the light is thrown into the camera module 520 along the path of the plate, the blood sample and the observation hole, and the camera module 520 can take pictures of the microorganisms in the blood sample.
  • the support plate 511 is provided with a light source 530 in an area corresponding to the peripheral side of the second limiting groove, and the light source 530 illuminates the plate, so that the light refracted by the blood sample into the camera module 520 is more sufficient, and the camera module 520 Take clearer images of microorganisms.
  • the light source 530 can be an LED light strip.
  • a diffuser plate is arranged between the light source 530 and the plate, and the diffuser plate makes the light projection direction of the light source 530 wider, thereby making the brightness of the plate more uniform.
  • the conveying device 600 includes a second front-rear moving mechanism 610, a left-right moving mechanism 620, a second rotational driving mechanism 630, a lifting moving mechanism 640, and a second plate gripper 650, which are connected in sequence. Station 100 connections.
  • the second front-rear movement mechanism 610 can drive the left-right movement mechanism 620, the second rotation driving mechanism 630, the lifting movement mechanism 640 and the second plate gripper 650 to move in the front-rear direction, and the left-right movement mechanism 620 can drive the second rotation driving mechanism 630, the lifting mechanism
  • the moving mechanism 640 and the second plate gripper 650 move in the left and right directions;
  • the second rotational drive mechanism 630 can drive the lift movement mechanism 640 and the second plate gripper 650 to rotate;
  • the lift movement mechanism 640 can drive the second plate gripper 650 to rise and fall, That is, the second plate gripper 650 has the functions of moving forward and backward, left and right, and up and down, and rotating around a vertical axis.
  • the second front and rear moving mechanism 610 includes a third screw pair, a guide rail and a guide block that cooperate with each other.
  • the third screw pair, the guide rail and the guide block are all arranged on the machine table 100.
  • the left and right moving mechanism 620 is connected to the guide block, the third screw
  • the output terminal of the lever pair is connected.
  • the structures of the left-right moving mechanism 620 , the up-and-down moving mechanism 640 and the second front-rear moving mechanism 610 are similar, and will not be described redundantly here.
  • the second rotational driving mechanism 630 may be a third motor.

Abstract

Disclosed in the present invention is a blood sample cultivation and testing workstation, comprising a platform, a plate blood-taking device, a drug susceptibility paper dispenser, a cultivation assembly, a testing device and a conveying device. The platform is provided with a support. The plate blood-taking device comprises a cultivation bottle clamping jaw, a blood-taking member clamping jaw and a first plate clamping jaw, which are all disposed on the support, wherein the cultivation bottle clamping jaw and the first plate clamping jaw are respectively arranged facing downwards and upwards; and the cultivation bottle clamping jaw, the blood-taking member clamping jaw and the first plate clamping jaw can be sequentially arranged from top to bottom. The drug susceptibility paper dispenser is disposed on the support, the drug susceptibility paper dispenser can directly face the first plate clamping jaw, and the drug susceptibility paper dispenser is used for putting drug susceptibility paper into a plate. The cultivation assembly and the testing device are both disposed on the platform; and the conveying device is arranged on the platform, and the conveying device can place the plate on the first plate clamping jaw, the cultivation assembly or the testing device. The blood sample cultivation and testing workstation has a high degree of automation, and can replace people to complete blood cultivation and testing, thereby improving efficiency and reducing labor costs.

Description

血样培养检测工作站Blood sample culture testing workstation 技术领域technical field
本发明涉及医疗设备技术领域,特别涉及一种血样培养检测工作站。The invention relates to the technical field of medical equipment, in particular to a blood sample culture detection workstation.
背景技术Background technique
血培养是把静脉穿刺获得的血液接种到一个或多个培养瓶或培养管中,用来发现、识别细菌或其它可培养分离的微生物,这些微生物存在于血液中形成菌血症或真菌菌血症。在病人的血液中检测出微生物对感染性疾病的诊断、治疗和预后有重要的临床意义。血培养一般包括以下操作,血液接种到培养瓶形成血样,然后将培养瓶置于培养机构上,培养机构对血样进行培养,接着需要将培养结束后的血样进行药敏检测,此时需要将血样移进平皿,并将药敏纸与血样接触,通过观测药敏纸的颜色变化确认药敏检测的效果。现阶段,血样培养检测步骤较多,包括血液接种、血样涂覆平皿、血样的再培养和检测等,各个步骤都具有相应的设备完成,但均需要人员操作,人员的工作量大,效率低。Blood culture is the inoculation of blood obtained by venipuncture into one or more culture flasks or culture tubes to find and identify bacteria or other culturable and isolated microorganisms that exist in the blood to form bacteremia or fungal bacteremia disease. The detection of microorganisms in the blood of patients has important clinical significance for the diagnosis, treatment and prognosis of infectious diseases. Blood culture generally includes the following operations. The blood is inoculated into a culture bottle to form a blood sample, and then the culture bottle is placed on the culture institution. Move it into a plate, contact the drug sensitive paper with the blood sample, and confirm the effect of drug sensitivity detection by observing the color change of the drug sensitive paper. At this stage, there are many blood sample culture detection steps, including blood inoculation, blood sample coating plate, blood sample re-cultivation and detection, etc. Each step is completed with corresponding equipment, but all require personnel to operate, the workload of personnel is large, and the efficiency is low. .
转移血样时,一般是通过抽吸装置将血样滴进或抽进平皿,而由于平皿尺寸较大,血样的量有限,血样无法涂满平皿,且药敏纸在平皿中的位置无法固定,容易出现药敏纸不沾上血样的情况,进而导致药敏检测无法进行。When transferring a blood sample, the blood sample is generally dropped or drawn into the plate by a suction device. However, due to the large size of the plate and the limited amount of blood sample, the blood sample cannot be filled with the plate, and the position of the drug sensitive paper in the plate cannot be fixed, which is easy to use. The drug susceptibility paper is not stained with blood samples, which makes the drug susceptibility test impossible.
发明内容SUMMARY OF THE INVENTION
本发明旨在至少解决现有技术中存在的技术问题之一。为此,本发明提出一种血样培养检测工作站,能够代替人完成血培养和检测,提高效率。The present invention aims to solve at least one of the technical problems existing in the prior art. To this end, the present invention proposes a blood sample culture detection workstation, which can replace humans to complete blood culture and detection and improve efficiency.
根据本发明的实施例的血样培养检测工作站,包括机台、平皿取血装置、药敏纸分配器、培养组件、检测装置和搬运装置。所述机台上设有支架;所述平皿取血装置包括均设于所述支架上的培养瓶夹爪、取血件夹爪和第一平皿夹爪,所述培养瓶夹爪和所述第一平皿夹爪分别朝下和朝上设置,所述培养瓶夹爪、所述取血件夹爪和所述第一平皿夹爪可处于由上往下依次设置状态;所述药敏纸分配器设于所述支架上,所述药敏纸分配器可正对所述第一平皿夹爪,所述药敏纸分 配器用于往平皿内投放药敏纸;所述培养组件和所述检测装置均设于所述机台上;所述搬运装置设于所述机台上,所述搬运装置可将所述平皿置于所述第一平皿夹爪或所述培养组件或所述检测装置上。A blood sample culture detection workstation according to an embodiment of the present invention includes a machine table, a blood-taking device for a plate, a drug-sensitive paper dispenser, a culture component, a detection device, and a handling device. The machine table is provided with a bracket; the plate blood taking device includes a culture bottle clamping claw, a blood sampling piece clamping claw and a first plate clamping claw all arranged on the bracket, the culture bottle clamping claw and the The first plate gripper is set downward and upward respectively, and the culture bottle gripper, the blood collection piece gripper and the first dish gripper can be arranged in order from top to bottom; the drug-sensitive paper The dispenser is arranged on the support, the drug-sensitive paper dispenser can face the first plate gripper, and the drug-sensitive paper dispenser is used to put the drug-sensitive paper into the plate; the culture component and the The detection devices are all arranged on the machine table; the handling device is arranged on the machine table, and the transportation device can place the plate on the first plate gripper or the culture component or the detection on the device.
根据本发明实施例的血样培养检测工作站,至少具有如下有益效果:培养瓶夹爪、取血件夹爪和第一平皿夹爪分别夹持培养瓶、取血件和平皿,当所述培养瓶夹爪、所述取血件夹爪和所述第一平皿夹爪处于由上往下依次设置状态时,取血件可扎破培养瓶的瓶盖,培养瓶内的血样将落入平皿内,然后药敏纸分配器往平皿内投放药敏纸,接着搬运装置将第一平皿夹爪上的平皿搬运至培养组件内,血样在培养组件内被培养后,由搬运装置将培养组件内的平皿搬运至检测装置上,检测装置对平皿内的血样进行观测,观测血样的微生物大小、形状和药敏纸附近有无微生物生长等,判断出微生物的种类以及得出药敏检测的结果。血样培养检测工作站自动化程度高,能够代替人完成血培养和检测,提高了效率,降低了人力成本。The blood sample culture detection workstation according to the embodiment of the present invention has at least the following beneficial effects: the culture bottle clamping jaw, the blood sampling piece clamping claw and the first plate clamping claw respectively clamp the culture bottle, the blood sampling piece and the plate, and when the culture bottle is clamped When the jaws, the jaws of the blood collection piece and the jaws of the first plate are arranged in order from top to bottom, the blood collection piece can pierce the bottle cap of the culture bottle, and the blood sample in the culture bottle will fall into the plate. , and then the drug sensitive paper dispenser puts the drug sensitive paper into the plate, and then the transport device transports the plate on the first plate gripper into the culture component. After the blood sample is cultured in the culture component, the transport device transfers the The plate is transported to the detection device, and the detection device observes the blood sample in the plate, observes the size and shape of the microorganisms in the blood sample and whether there is microbial growth near the drug sensitive paper, etc., to determine the type of microorganisms and obtain the results of drug sensitivity testing. The blood sample culture detection workstation has a high degree of automation and can replace humans to complete blood culture and detection, which improves efficiency and reduces labor costs.
根据本发明的一些实施例,所述支架上设有沿前后方向移动的第一安装板,所述第一安装板上连接有沿左右方向移动的第二安装板,所述第一平皿夹爪可前后滑移地设于所述支架上,且所述第一平皿夹爪可转动,所述培养瓶夹爪可升降地设于所述第一安装板上,所述培养瓶夹爪用于夹持倒置的培养瓶,所述第一安装板可驱使所述培养瓶处于所述第一平皿夹爪的上方,所述取血件夹爪与所述第二安装板连接,所述第二安装板可驱使取血件正对所述培养瓶的瓶口。According to some embodiments of the present invention, the bracket is provided with a first installation plate that moves in the front-rear direction, the first installation plate is connected with a second installation plate that moves in the left-right direction, and the first plate gripper It can be slid back and forth on the bracket, and the first plate gripper can be rotated. The culture bottle gripper can be lifted up and down on the first mounting plate. Holding the inverted culture bottle, the first mounting plate can drive the culture bottle to be above the first plate gripper, the blood sampling piece gripper is connected with the second mounting plate, the second The mounting plate can drive the blood sampling piece to face the bottle opening of the culture bottle.
根据本发明的一些实施例,所述支架上还设有第一前后移动机构,所述第一前后移动机构的输出端上连接有载台,所述第一平皿夹爪可转动地连接于所述载台上。According to some embodiments of the present invention, the bracket is further provided with a first forward and backward moving mechanism, the output end of the first forward and backward moving mechanism is connected with a stage, and the first plate gripper is rotatably connected to the on the stage.
根据本发明的一些实施例,所述第一平皿夹爪包括载板和两块支撑板,两块所述支撑板均设于所述载板上,所述载板可转动地设于所述载台上,两块所述支撑板的上表面相对应的一侧均开设有第一限位槽,两个所述第一限位槽的底部可抵接所述平皿的底部,两个所述第一限位槽的侧壁可抵接所述平皿的侧壁。According to some embodiments of the present invention, the first plate gripper includes a carrier plate and two support plates, both of which are arranged on the carrier plate, and the carrier plate is rotatably arranged on the carrier plate. On the carrier, first limit grooves are opened on the corresponding sides of the upper surfaces of the two support plates, the bottoms of the two first limit grooves can abut the bottom of the plate, and the two The side wall of the first limiting groove can abut against the side wall of the plate.
根据本发明的一些实施例,所述第一前后移动机构包括第一直线驱动机构以及相互配合的第一滑轨和第一滑块,所述第一滑轨沿前后方向延伸并与所述支架连接,所述载台与所述第一滑块连接,所述第一直线驱动机构的输出端与所述第一滑块或所述载台连接。According to some embodiments of the present invention, the first forward and backward moving mechanism includes a first linear drive mechanism, and a first sliding rail and a first sliding block cooperating with each other, the first sliding rail extending in the forward and backward direction and being connected with the The support is connected, the carrier is connected with the first sliding block, and the output end of the first linear drive mechanism is connected with the first sliding block or the carrier.
根据本发明的一些实施例,所述支架在对应所述第一滑轨上方的区域设有开盖机构,所述开盖机构包括可升降的提升块,所述提升块的前侧壁上设有用于收纳所述平皿的第一收纳槽,所述第一收纳槽的底部设有可供所述平皿的盒体和第一平皿夹爪伸进的第一避让槽,所述第一收纳槽的底壁可抵在所述平皿的盖子的下端面上。According to some embodiments of the present invention, the bracket is provided with a cover opening mechanism in an area corresponding to the upper part of the first slide rail, and the cover opening mechanism includes a lifting block that can be raised and lowered, and a front side wall of the lifting block is provided with a cover opening mechanism. There is a first receiving groove for accommodating the plate, the bottom of the first receiving groove is provided with a first escape groove into which the box body of the plate and the first plate jaw can extend, the first receiving groove The bottom wall of the plate can abut on the lower end surface of the lid of the plate.
根据本发明的一些实施例,所述开盖机构还包括凸轮顶升机构以及相互配合的第二滑轨和第二滑块,所述第二滑轨设于所述机台上且沿上下方向延伸,所述提升块与所述第二滑块连接,所述凸轮顶升机构设于所述机台上且所述凸轮顶升机构的输出端与所述提升块或所述第二滑块铰接。According to some embodiments of the present invention, the lid opening mechanism further includes a cam lifting mechanism and a second sliding rail and a second sliding block that cooperate with each other, the second sliding rail is provided on the machine table and is in an up-down direction extension, the lifting block is connected with the second sliding block, the cam lifting mechanism is arranged on the machine table, and the output end of the cam lifting mechanism is connected to the lifting block or the second sliding block Hinged.
根据本发明的一些实施例,所述检测装置包括设于所述机台上的支撑架以及朝上设于所述支撑架上的摄像模组,所述支撑架在对应所述摄像模组上方的区域设有托板,所述托板上设有限位所述平皿的第二限位槽,所述第二限位槽的槽底设有观察孔。According to some embodiments of the present invention, the detection device includes a support frame disposed on the machine table and a camera module upwardly disposed on the support frame, and the support frame is above the camera module corresponding to the A support plate is arranged in the area of the plate, a second limit groove for limiting the plate is arranged on the support plate, and an observation hole is arranged at the bottom of the second limit groove.
根据本发明的一些实施例,所述托板在对应所述第二限位槽周侧的区域设有光源。According to some embodiments of the present invention, the support plate is provided with a light source in a region corresponding to the peripheral side of the second limiting groove.
根据本发明的一些实施例,所述搬运装置包括依次连接的第二前后移动机构、左右移动机构、第二旋转驱动机构、升降移动机构和第二平皿夹爪,所述第二前后移动机构与所述机台连接。According to some embodiments of the present invention, the conveying device includes a second forward-backward moving mechanism, a left-right moving mechanism, a second rotational driving mechanism, a lifting moving mechanism, and a second plate gripper, which are connected in sequence, and the second forward-backward moving mechanism is connected to The machine is connected.
本发明的附加方面和优点将在下面的描述中部分给出,部分将从下面的描述中变得明显,或通过本发明的实践了解到。Additional aspects and advantages of the present invention will be set forth, in part, from the following description, and in part will be apparent from the following description, or may be learned by practice of the invention.
附图说明Description of drawings
本发明的上述和/或附加的方面和优点从结合下面附图对实施例的描述中将变得明显和容易理解,其中:The above and/or additional aspects and advantages of the present invention will become apparent and readily understood from the following description of embodiments taken in conjunction with the accompanying drawings, wherein:
图1为本发明实施例血样培养检测工作站的结构示意图;1 is a schematic structural diagram of a blood sample culture detection workstation according to an embodiment of the present invention;
图2为本发明实施例血样培养检测工作站中的平皿取血装置的结构示意图;2 is a schematic structural diagram of a plate blood sampling device in a blood sample culture detection workstation according to an embodiment of the present invention;
图3为图2中A处的局部放大示意图;Fig. 3 is the partial enlarged schematic diagram of A place in Fig. 2;
图4为本发明实施例血样培养检测工作站中的开盖机构的结构示意图;4 is a schematic structural diagram of an opening mechanism in a blood sample culture detection workstation according to an embodiment of the present invention;
图5为本发明实施例血样培养检测工作站中的检测装置的结构示意图;5 is a schematic structural diagram of a detection device in a blood sample culture detection workstation according to an embodiment of the present invention;
图6为本发明实施例血样培养检测工作站中的搬运装置的结构示意图。FIG. 6 is a schematic structural diagram of a handling device in a blood sample culture detection workstation according to an embodiment of the present invention.
附图标记:Reference number:
机台100、支架110、第二安装板120、第三滑轨121、第三滑块122、齿轮123、齿条124、第一前后移动机构130、第一直线驱动机构131、第一滑轨132、第四滑轨140、第一安装板150、升降驱动机构151、第三安装板152、翻转板160、第二直线驱动机构170、平皿取血装置200、培养瓶夹爪210、取血件夹爪220、第一平皿夹爪230、载板231、支撑板232、药敏纸分配器300、培养组件400、检测装置500、支撑架510、托板511、摄像模组520、光源530、搬运装置600、第二前后移动机构610、左右移动机构620、第二旋转驱动机构630、升降移动机构640、第二平皿夹爪650、载台700、第一旋转驱动机构710、第一限位槽800、开盖机构900、提升块910、第一收纳槽911、凸轮顶升机构920、第二滑轨930、第二滑块940。Machine table 100, bracket 110, second mounting plate 120, third slide rail 121, third slider 122, gear 123, rack 124, first forward and backward moving mechanism 130, first linear drive mechanism 131, first slide Rail 132, fourth slide rail 140, first mounting plate 150, elevating drive mechanism 151, third mounting plate 152, turning plate 160, second linear drive mechanism 170, plate blood sampling device 200, culture bottle gripper 210, Blood sample gripper 220, first plate gripper 230, carrier plate 231, support plate 232, drug sensitive paper dispenser 300, culture assembly 400, detection device 500, support frame 510, support plate 511, camera module 520, light source 530, conveying device 600, second forward and backward movement mechanism 610, left and right movement mechanism 620, second rotation drive mechanism 630, lift movement mechanism 640, second plate gripper 650, stage 700, first rotation drive mechanism 710, first The limiting slot 800 , the cover opening mechanism 900 , the lifting block 910 , the first receiving slot 911 , the cam lifting mechanism 920 , the second sliding rail 930 , and the second sliding block 940 .
具体实施方式Detailed ways
下面详细描述本发明的实施例,实施例的示例在附图中示出,其中自始至终相同或类似的标号表示相同或类似的元件或具有相同或类似功能的元件。下面通过参考附图描述的实施例是示例性的,仅用于解释本发明,而不能理解为对本发明的限制。Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals refer to the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary, only used to explain the present invention, and should not be construed as a limitation of the present invention.
在本发明的描述中,需要理解的是,涉及到方位描述,例如上、下、前、后、左、右等指示的方位或位置关系可为基于附图所示的方位或位置关系,仅是为了 便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本发明的限制。In the description of the present invention, it should be understood that when it comes to the orientation description, for example, the orientation or positional relationship indicated by up, down, front, rear, left, right, etc., may be based on the orientation or positional relationship shown in the drawings, only It is to facilitate the description of the present invention and to simplify the description, rather than indicating or implying that the device or element referred to must have a particular orientation, be constructed and operate in a particular orientation, and therefore should not be construed as limiting the invention.
在本发明的描述中,若干的含义是一个或者多个,多个的含义是两个及两个以上,大于、小于、超过等理解为不包括本数,以上、以下、以内等理解为包括本数。如果有描述到第一、第二只是用于区分技术特征为目的,而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量或者隐含指明所指示的技术特征的先后关系。In the description of the present invention, the meaning of several is one or more, the meaning of multiple is two or more, greater than, less than, exceeding, etc. are understood as not including this number, above, below, within, etc. are understood as including this number . If it is described that the first and the second are only for the purpose of distinguishing technical features, it cannot be understood as indicating or implying relative importance, or indicating the number of the indicated technical features or the order of the indicated technical features. relation.
本发明的描述中,除非另有明确的限定,设置、安装、连接等词语应做广义理解,所属技术领域技术人员可以结合技术方案的具体内容合理确定上述词语在本发明中的具体含义。In the description of the present invention, unless otherwise clearly defined, words such as setting, installation, connection should be understood in a broad sense, and those skilled in the art can reasonably determine the specific meanings of the above words in the present invention in combination with the specific content of the technical solution.
参照图1至图3,本发明公开了一种血样培养检测工作站,包括机台100、平皿取血装置200、药敏纸分配器300、培养组件400、检测装置500和搬运装置600。机台100上设有支架110;平皿取血装置200包括均设于支架110上的培养瓶夹爪210、取血件夹爪220和第一平皿夹爪230,培养瓶夹爪210和第一平皿夹爪230分别朝下和朝上设置,培养瓶夹爪210、取血件夹爪220和第一平皿夹爪230可处于由上往下依次设置状态;药敏纸分配器300设于支架110上,药敏纸分配器300可正对第一平皿夹爪230,药敏纸分配器300用于往平皿内投放药敏纸;培养组件400和检测装置500均设于机台100上;搬运装置600设于机台100上,搬运装置600可将平皿置于第一平皿夹爪230或培养组件400或检测装置500上。1 to 3 , the present invention discloses a blood sample culture detection workstation, including a machine 100 , a plate blood sampling device 200 , a drug sensitive paper dispenser 300 , a culture assembly 400 , a detection device 500 and a handling device 600 . The machine table 100 is provided with a bracket 110; the plate blood taking device 200 includes a culture bottle gripper 210, a blood sampling piece gripper 220 and a first plate gripper 230, which are all arranged on the support 110. The culture bottle gripper 210 and the first plate gripper 230 The plate clamping jaws 230 are respectively set downward and upward, the culture bottle clamping jaw 210, the blood sampling piece clamping jaw 220 and the first plate clamping jaw 230 can be arranged in order from top to bottom; the drug sensitive paper dispenser 300 is arranged on the bracket On 110, the drug-sensitive paper dispenser 300 can face the first plate gripper 230, and the drug-sensitive paper dispenser 300 is used to put the drug-sensitive paper into the plate; the culture assembly 400 and the detection device 500 are both arranged on the machine 100; The handling device 600 is disposed on the machine table 100 , and the handling device 600 can place the plate on the first plate gripper 230 or the culture assembly 400 or the detection device 500 .
培养瓶夹爪210、取血件夹爪220和第一平皿夹爪230分别夹持培养瓶、取血件和平皿,当培养瓶夹爪210、取血件夹爪220和第一平皿夹爪230处于由上往下依次设置状态时,取血件可扎破培养瓶的瓶盖,培养瓶内的血样将落入平皿内,然后药敏纸分配器300往平皿内投放药敏纸,接着搬运装置600将第一平皿夹爪230上的平皿搬运至培养组件400内,血样在培养组件400内被培养后,由搬运装置600将培养组件400内的平皿搬运至检测装置500上,检测装置500 对平皿内的血样进行观测,观测血样的微生物大小、形状和药敏纸附近有无微生物生长等,判断出微生物的种类以及得出药敏检测的结果。血样培养检测工作站自动化程度高,能够代替人完成血培养和检测,提高了效率,降低了人力成本。The culture bottle gripper 210, the blood collection piece gripper 220 and the first plate gripper 230 respectively clamp the culture flask, the blood collection piece and the flat dish. When the culture bottle gripper 210, the blood collection piece gripper 220 and the first plate gripper When the 230 is set in order from top to bottom, the blood sampling piece can pierce the cap of the culture bottle, the blood sample in the culture bottle will fall into the plate, and then the drug sensitive paper dispenser 300 will put the drug sensitive paper into the plate, and then The transport device 600 transports the plate on the first plate gripper 230 into the culture assembly 400. After the blood sample is cultured in the culture assembly 400, the transport device 600 transports the plate in the culture assembly 400 to the detection device 500. The detection device 500 Observing the blood samples in the plate, observing the size and shape of the microorganisms in the blood samples and whether there is microbial growth near the drug sensitive paper, etc., to determine the type of microorganisms and obtain the results of drug sensitivity testing. The blood sample culture detection workstation has a high degree of automation and can replace humans to complete blood culture and detection, which improves efficiency and reduces labor costs.
应当理解的是,取血件呈套筒状,取血件内设有针,当培养瓶夹爪210携带着培养瓶下降时,取血件即可套在培养瓶的瓶嘴上,针即可将瓶盖扎破一个小孔,血样即可通过小孔落入平皿内。为避免不同血样或者血样交叉污染,取血件为一次性用品,取血件被使用过一次后,取血件夹爪220即丢弃改取血件,然后取血件夹爪220夹持一个新的取血件。平皿为常见的透明部件,平皿包括盒体和盖子。药敏纸分配器300也是常见的部件,将药敏纸置于药敏纸分配器300内,药敏纸分配器300即可逐个将药敏纸释放出来。培养组件400为常见的温育箱。It should be understood that the blood sampling piece is in the shape of a sleeve, and the blood sampling piece is provided with a needle. When the culture bottle gripper 210 is lowered with the culture bottle, the blood sampling piece can be sleeved on the bottle mouth of the culture bottle, and the needle is The cap can be pierced through a small hole, and the blood sample can fall into the dish through the small hole. In order to avoid cross-contamination of different blood samples or blood samples, the blood collection piece is a one-time item. After the blood collection piece is used once, the blood collection piece gripper 220 is discarded and replaced with a blood collection piece, and then a new blood collection piece is clamped by the blood collection piece gripper 220. blood collection. The plate is a common transparent part, and the plate includes a box body and a lid. The drug-sensitive paper dispenser 300 is also a common component, and the drug-sensitive paper is placed in the drug-sensitive paper dispenser 300, and the drug-sensitive paper dispenser 300 can release the drug-sensitive papers one by one. The culture assembly 400 is a common incubator.
本发明的一些实施例中,支架110上设有沿前后方向移动的第一安装板150,第一安装板150上连接有沿左右方向移动的第二安装板120,第一平皿夹爪230可前后滑移地设于支架110上,且第一平皿夹爪230可转动,培养瓶夹爪210可升降地设于第一安装板150上,培养瓶夹爪210用于夹持倒置的培养瓶,第一安装板150可驱使培养瓶夹爪210/培养瓶处于第一平皿夹爪230的上方,取血件夹爪220与第二安装板120连接,第二安装板120可驱使取血件夹爪220/取血件正对培养瓶的瓶口。In some embodiments of the present invention, the bracket 110 is provided with a first mounting plate 150 that moves in the front-rear direction, the first mounting plate 150 is connected to a second mounting plate 120 that moves in the left-right direction, and the first plate gripper 230 can be The first plate clamping jaw 230 is rotatable, and the culture bottle clamping jaw 210 can be lifted and lowered on the first mounting plate 150. The culture bottle clamping jaw 210 is used for clamping the inverted culture bottle. , the first mounting plate 150 can drive the culture bottle gripper 210/the culture bottle to be above the first plate gripper 230, the blood sampling piece gripper 220 is connected with the second mounting plate 120, and the second mounting plate 120 can drive the blood sampling piece The clamping jaw 220/blood sampling piece is facing the bottle mouth of the culture bottle.
需要将血样或血液转移进平皿时,第一平皿夹爪230夹持未使用过的平皿并固定平皿在支架110上的位置,培养瓶夹爪210夹持盛装有血样的培养瓶,取血件夹爪220夹持取血件。通过移动第一安装板150和第二安装板120,使得培养瓶和取血件处于同一竖直轴线上,且取血件的下方正对平皿,培养瓶夹爪210驱使培养瓶下降,取血件将扎破培养瓶的瓶盖,血样落入平皿,此时,第一安装板150携带着培养瓶和取血件沿前后方向移动,第一平皿夹爪230驱动平皿转动,最终可使得混合液落入平皿后呈螺旋状分布,也即是呈蚊香状分布于平皿内。由于血样较均匀地分布于平皿内,保证了药敏纸能沾上血样,使得药敏检测可顺利进行,避免部分血样无法进行药敏检测。When the blood sample or blood needs to be transferred into the plate, the first plate clamp 230 clamps the unused plate and fixes the position of the plate on the support 110, and the culture bottle clamp 210 clamps the culture bottle containing the blood sample, and the blood sample is collected. The jaws 220 hold the blood sampling piece. By moving the first mounting plate 150 and the second mounting plate 120 so that the culture bottle and the blood collection piece are on the same vertical axis, and the bottom of the blood collection piece is facing the plate, the culture bottle gripper 210 drives the culture bottle to descend, and blood collection is performed. The first mounting plate 150 carries the culture bottle and the blood sampling piece to move in the front-rear direction, and the first plate gripper 230 drives the plate to rotate, which can finally make the mixing After the liquid falls into the plate, it is distributed in a spiral shape, that is, it is distributed in the plate in the form of mosquito coils. Since the blood samples are evenly distributed in the plate, it is ensured that the drug sensitive paper can be stained with the blood samples, so that the drug sensitivity test can be carried out smoothly, and it is avoided that some blood samples cannot be tested for drug sensitivity.
取血件夹爪220和培养瓶夹爪210分别夹持取血件和培养瓶的动作可参考如下,第二安装板120驱使取血件夹爪220移动,使得取血件夹爪220和培养瓶夹爪210不在同一轴线上,进而便于取血件夹爪220和培养瓶夹爪210分别夹持取血件和培养瓶,避免取血件夹爪220和培养瓶夹爪210相互干涉;当取血件夹爪220和培养瓶夹爪210分别夹持取血件和培养瓶完毕,第二安装板120驱使取血件夹爪220移动,使得取血件夹爪220与培养瓶夹爪210处于同一轴线上。然后,第一平皿夹爪230携带着平皿移动至取血件夹爪220的下方,从而完成将血样转移至平皿内的准备。The actions of the blood sampling piece clamping jaw 220 and the culture bottle clamping claw 210 respectively holding the blood sampling piece and the culture bottle can be referred to as follows. The second mounting plate 120 drives the blood sampling piece clamping claw 220 to move, so that the blood sampling piece clamping jaw 220 and the culture bottle are moved. The bottle clamping jaws 210 are not on the same axis, so that it is convenient for the blood sampling piece clamping claw 220 and the culture bottle clamping claw 210 to clamp the blood sampling piece and the culture bottle respectively, so as to avoid mutual interference between the blood sampling piece clamping claw 220 and the culture bottle clamping claw 210; After the blood sampling piece clamping claw 220 and the culture bottle clamping claw 210 respectively clamp the blood sampling piece and the culture bottle, the second mounting plate 120 drives the blood sampling piece clamping claw 220 to move, so that the blood sampling piece clamping claw 220 and the culture bottle clamping claw 210 on the same axis. Then, the first plate gripper 230 carries the plate and moves under the blood collection member gripper 220, so as to complete the preparation for transferring the blood sample into the plate.
本发明的一些实施例中,机台100上还设有第一前后移动机构130,第一前后移动机构130的输出端上连接有载台700,第一平皿夹爪230可转动地连接于载台700上。第一前后移动机构130通过载台700驱动第一平皿夹爪230在前后方向上移动,进而完成将其他区域的平皿输送至特定区域的功能,避免培养瓶夹爪210和取血件夹爪220对第一平皿夹爪230上料平皿的干涉。In some embodiments of the present invention, the machine table 100 is further provided with a first forward and backward moving mechanism 130 , the output end of the first forward and backward moving mechanism 130 is connected with the carrier table 700 , and the first plate gripper 230 is rotatably connected to the carrier table 700 . on Taiwan 700. The first back-and-forth moving mechanism 130 drives the first plate gripper 230 to move in the front-rear direction through the stage 700, thereby completing the function of transporting dishes from other areas to a specific area, avoiding the culture bottle gripper 210 and the blood collection piece gripper 220 Interference with the first plate gripper 230 for loading the plate.
本发明的一些实施例中,第一平皿夹爪230包括载板231和两块支撑板232,两块支撑板232均设于载板231上,载板231可转动地设于载台700上,两块支撑板232的上表面相对应的一侧均开设有第一限位槽800,两个第一限位槽800的底部可抵接平皿的底部,两个第一限位槽800的侧壁可抵接平皿的侧壁。In some embodiments of the present invention, the first plate gripper 230 includes a carrier plate 231 and two support plates 232 . The two support plates 232 are both disposed on the carrier plate 231 , and the carrier plate 231 is rotatably disposed on the carrier platform 700 . , the corresponding sides of the upper surfaces of the two support plates 232 are provided with first limiting grooves 800 , the bottoms of the two first limiting grooves 800 can abut the bottom of the plate, and the two first limiting grooves 800 The side wall may abut the side wall of the plate.
当第一平皿夹爪230夹持平皿时,平皿的底部抵在第一限位槽800的槽底上,第一限位槽800的槽底起到支撑平皿的作用,平皿的侧壁抵在第一限位槽800的侧壁上,第一限位槽800的侧壁起到限位平皿在水平方向上移动的作用。When the first plate clamping jaw 230 clamps the plate, the bottom of the plate abuts on the bottom of the first limiting groove 800, the bottom of the first limiting groove 800 plays the role of supporting the plate, and the side wall of the plate abuts against the bottom of the first limiting groove 800. On the side wall of the first limiting slot 800 , the side wall of the first limiting slot 800 serves to limit the movement of the plate in the horizontal direction.
一些实施例中,两块支撑板232可相对滑移地设于载板231上,两块支撑板232的间距可调,使得两个第一限位槽800合成的空间面积大小可调,进而使得第一平皿夹爪230可夹持不同大小的平皿。In some embodiments, the two support plates 232 are slidably disposed on the carrier plate 231, and the distance between the two support plates 232 can be adjusted, so that the combined space area of the two first limiting grooves 800 can be adjusted. The first plate clamping jaws 230 can hold plates of different sizes.
载台700上设有第一旋转驱动机构710,第一平皿夹爪230可通过轴承与载台700连接,第一旋转驱动机构710与载板231传动连接。第一旋转驱动机构710驱使载板231转动,进而使得平皿转动。The carrier 700 is provided with a first rotational drive mechanism 710 , the first plate gripper 230 can be connected to the carrier 700 through a bearing, and the first rotational drive mechanism 710 is connected to the carrier plate 231 by transmission. The first rotation driving mechanism 710 drives the carrier plate 231 to rotate, thereby making the plate rotate.
可以理解的是,第一平皿夹爪230朝上设置,进而使得平皿朝上。第一旋转驱动机构710为第二电机,第二电机的输出端上设有第一传动齿轮,载板231上设有与第一传动齿轮啮合的第二传动齿轮,第二电机通过第一传动齿轮和第二传动齿轮驱动载板231转动。It can be understood that, the first plate clamping jaws 230 are disposed upward, so as to make the plate face upward. The first rotary drive mechanism 710 is a second motor, the output end of the second motor is provided with a first transmission gear, the carrier plate 231 is provided with a second transmission gear that meshes with the first transmission gear, and the second motor is driven by the first transmission gear. The gear and the second transmission gear drive the carrier plate 231 to rotate.
本发明的一些实施例中,第一前后移动机构130包括第一直线驱动机构131以及相互配合的第一滑轨132和第一滑块,第一滑轨132沿前后方向延伸并与机台100连接,载台700与第一滑块连接,第一直线驱动机构131的输出端与第一滑块或载台700连接,使得第一直线驱动机构131可驱动载台700在第一滑轨132上沿前后方向移动。第一直线驱动机构131可为第二丝杠副或第一电缸或第一气缸。In some embodiments of the present invention, the first forward and backward moving mechanism 130 includes a first linear drive mechanism 131 and a first sliding rail 132 and a first sliding block that cooperate with each other. The first sliding rail 132 extends in the front and rear direction and is connected to the machine table. 100 is connected, the carrier 700 is connected with the first slider, and the output end of the first linear drive mechanism 131 is connected with the first slider or the carrier 700, so that the first linear drive mechanism 131 can drive the carrier 700 in the first The slide rail 132 moves in the front-rear direction. The first linear drive mechanism 131 can be a second screw pair or a first electric cylinder or a first air cylinder.
本发明的一些实施例中,支架110在对应第一滑轨132上方的区域设有开盖机构900,开盖机构900包括可升降的提升块910,提升块910的前侧壁上设有用于收纳平皿的第一收纳槽911,第一收纳槽911的底部设有可供平皿的盒体和第一平皿夹爪230伸进的第一避让槽,第一收纳槽911的底壁可抵在平皿的盖子的下端面上。In some embodiments of the present invention, the bracket 110 is provided with a cover opening mechanism 900 in the area corresponding to the upper part of the first slide rail 132 , and the cover opening mechanism 900 includes a lifting block 910 that can be lifted and lowered. The first receiving groove 911 for accommodating the plate, the bottom of the first receiving groove 911 is provided with a first escape groove for the box body of the plate and the first plate jaw 230 to extend into, and the bottom wall of the first receiving groove 911 can abut against the plate. on the lower end of the lid of the dish.
提升块910处于低位时,第一收纳槽911与第一平皿夹爪230上的平皿处于同一高度,第一平皿夹爪230携带着平皿移动,第一平皿夹爪230和平皿即可分别进入第一避让槽和第一收纳槽911,此时,驱动提升块910上升,第一收纳槽911的底壁将平皿的盖子提起来,盖子暂存于提升块910上,平皿的盒体仍处于第一平皿夹爪230上,进而完成了平皿的开盖。When the lifting block 910 is in a low position, the first receiving groove 911 is at the same height as the plate on the first plate clamp 230, the first plate clamp 230 carries the plate to move, and the first plate clamp 230 and the plate can enter the first plate respectively. At this time, the lifting block 910 is driven to rise, the bottom wall of the first receiving groove 911 lifts the lid of the plate, the cover is temporarily stored on the lifting block 910, and the box of the plate is still in the first A plate clamping claw 230 is placed on the plate, thereby completing the opening of the plate.
参见图3,开盖机构900还包括凸轮顶升机构920以及相互配合的第二滑轨930和第二滑块940,第二滑轨930设于机台100上且沿上下方向延伸,提升块910与第二滑块940连接,凸轮顶升机构920设于机台100上且凸轮顶升机构920的输出端与提升块910或第二滑块940铰接,凸轮顶升机构920驱动提升块910的升降。凸轮顶升机构920为常见的部件,具有便于控制且结构简单的优点。Referring to FIG. 3 , the cover opening mechanism 900 further includes a cam jacking mechanism 920 and a second sliding rail 930 and a second sliding block 940 that cooperate with each other. The second sliding rail 930 is provided on the machine table 100 and extends in the up-down direction. The lifting block 910 is connected with the second sliding block 940, the cam lifting mechanism 920 is arranged on the machine table 100 and the output end of the cam lifting mechanism 920 is hinged with the lifting block 910 or the second sliding block 940, and the cam lifting mechanism 920 drives the lifting block 910 the lift. The cam jacking mechanism 920 is a common component and has the advantages of easy control and simple structure.
可以理解的是,凸轮顶升机构920包括连杆、设于支架110上的第三电机和 设于第三电机输出端上的转轮,连杆的一端和转轮的非轴线处铰接,连杆的另一端与提升块910或第二滑块940铰接。It can be understood that the cam jacking mechanism 920 includes a connecting rod, a third motor disposed on the bracket 110 and a runner disposed on the output end of the third motor, one end of the connecting rod is hinged with the non-axis of the runner, and the connection is The other end of the rod is hinged with the lifting block 910 or the second sliding block 940 .
参见图4,支架110在对应第一滑轨132上方的区域设有平皿翻转机构。平皿翻转机构包括可转动地设于支架110上的旋转轴和设于旋转轴上的翻转板160,翻转板160内设有暂存平皿的第二收纳槽,当平皿置于第二收纳槽内后,翻转板160绕旋转轴的轴线旋转180°,即可将平皿上下颠倒。翻转板160上设有与第二收纳槽相连通的第二避让槽,第一平皿夹爪230可伸进第二避让槽并将第二收纳槽内的平皿取走。Referring to FIG. 4 , the bracket 110 is provided with a plate turning mechanism in the region corresponding to the upper part of the first sliding rail 132 . The plate turning mechanism includes a rotating shaft rotatably arranged on the support 110 and a turning plate 160 arranged on the rotating shaft. The turning plate 160 is provided with a second receiving slot for temporarily storing the plate. When the plate is placed in the second receiving slot Then, the turning plate 160 is rotated 180° around the axis of the rotating shaft, and the plate can be turned upside down. The flip plate 160 is provided with a second avoidance groove communicating with the second storage groove, and the first plate clamping jaw 230 can extend into the second avoidance groove and remove the plate in the second storage groove.
本发明的一些实施例中,取血件夹爪220通过相互配合的第三滑轨121和第三滑块122与第二安装板120连接,第三滑轨121沿左右方向延伸,第二安装板120上设有第一电机,第一电机的输出端上设有齿轮123,第三滑块122或取血件夹爪220上设有与齿轮123相互配合的齿条124。第一电机通过齿轮123和齿轮123驱动第三滑块122/取血件夹爪220在第三滑轨121上移动。第一电机、齿轮123和齿轮123的结构简单,安装方便且便于控制。In some embodiments of the present invention, the blood sampling device clamping jaw 220 is connected to the second mounting plate 120 through a third sliding rail 121 and a third sliding block 122 that cooperate with each other. The third sliding rail 121 extends in the left-right direction, and the second mounting plate A first motor is provided on the plate 120 , a gear 123 is provided on the output end of the first motor, and a rack 124 is provided on the third sliding block 122 or the blood sampling claw 220 which cooperates with the gear 123 . The first motor drives the third sliding block 122/blood sampling claw 220 to move on the third sliding rail 121 through the gear 123 and the gear 123 . The structures of the first motor, the gear 123 and the gear 123 are simple, easy to install and easy to control.
本发明的一些实施例中,第一安装板150通过相互配合的第四滑块和第四滑轨140与支架110连接,第四滑轨140沿前后方向延伸,第一安装板150上设有升降驱动机构151和可升降的第三安装板152,培养瓶夹爪210通过第三安装板152与第一安装板150连接,升降驱动机构151的输出端与第三安装板152连接。第一安装板150通过第四滑块和第四滑轨140便于在支架110上沿前后方向移动;升降驱动机构151驱动第三安装板152升降,第三安装板152即携带着培养瓶夹爪210升降。In some embodiments of the present invention, the first mounting plate 150 is connected to the bracket 110 through a fourth sliding block and a fourth sliding rail 140 that cooperate with each other, the fourth sliding rail 140 extends in the front-rear direction, and the first mounting plate 150 is provided with The elevating drive mechanism 151 and the elevating third mounting plate 152 , the culture bottle gripper 210 is connected to the first mounting plate 150 through the third mounting plate 152 , and the output end of the elevating drive mechanism 151 is connected to the third mounting plate 152 . The first mounting plate 150 is facilitated to move in the front-rear direction on the bracket 110 through the fourth sliding block and the fourth sliding rail 140; the elevating driving mechanism 151 drives the third mounting plate 152 to ascend and descend, and the third mounting plate 152 carries the culture bottle clamps 210 lift.
进一步的,第三安装板152通过相配合的第五滑块和第五滑轨与第一安装板150连接。升降驱动机构151可为第一丝杠副或第二气缸或第二电缸。Further, the third mounting plate 152 is connected to the first mounting plate 150 through the matched fifth sliding block and fifth sliding rail. The lift driving mechanism 151 can be a first screw pair or a second air cylinder or a second electric cylinder.
本发明的一些实施例中,支架110上还设有第二直线驱动机构170,第二直线驱动机构170的输出端与第四滑轨140或第一安装板150连接,第二直线驱动机构170可驱动第四滑轨140/第一安装板150在支架110上沿前后方向一定。In some embodiments of the present invention, the bracket 110 is further provided with a second linear drive mechanism 170 , the output end of the second linear drive mechanism 170 is connected to the fourth slide rail 140 or the first mounting plate 150 , and the second linear drive mechanism 170 The fourth sliding rail 140/the first mounting plate 150 can be driven to be fixed on the bracket 110 in the front-rear direction.
参见图5,检测装置500包括设于机台100上的支撑架510以及朝上设于支撑架510上的摄像模组520,支撑架510在对应摄像模组520上方的区域设有托板511,托板511上设有限位平皿的第二限位槽,第二限位槽的槽底设有观察孔。Referring to FIG. 5 , the detection device 500 includes a support frame 510 disposed on the machine table 100 and a camera module 520 upwardly disposed on the support frame 510 . The support frame 510 is provided with a support plate 511 in the area above the corresponding camera module 520 . , the support plate 511 is provided with a second limiting groove for limiting the plate, and the bottom of the second limiting groove is provided with an observation hole.
搬运装置600经过微生物培养的平皿搬运至第二限位槽内,第二限位槽起到限位平皿的作用,光线沿平皿、血样和观察孔的路径投进摄像模组520,摄像模组520即可拍到血样内微生物的情况。The conveying device 600 is transported into the second limit groove through the plate of microorganism culture, the second limit groove plays the role of limiting the plate, and the light is thrown into the camera module 520 along the path of the plate, the blood sample and the observation hole, and the camera module 520 can take pictures of the microorganisms in the blood sample.
本发明的一些实施例中,托板511在对应第二限位槽周侧的区域设有光源530,光源530照亮平皿,使得血样折射进摄像模组520的光线更充足,摄像模组520拍摄微生物的图像更清晰。可以理解的是,光源530可为LED灯带。光源530和平皿之间设有扩散板,扩散板使得光源530的光投射方向更广,进而使得平皿的亮度更均匀。In some embodiments of the present invention, the support plate 511 is provided with a light source 530 in an area corresponding to the peripheral side of the second limiting groove, and the light source 530 illuminates the plate, so that the light refracted by the blood sample into the camera module 520 is more sufficient, and the camera module 520 Take clearer images of microorganisms. It can be understood that the light source 530 can be an LED light strip. A diffuser plate is arranged between the light source 530 and the plate, and the diffuser plate makes the light projection direction of the light source 530 wider, thereby making the brightness of the plate more uniform.
参见图6,搬运装置600包括依次连接的第二前后移动机构610、左右移动机构620、第二旋转驱动机构630、升降移动机构640和第二平皿夹爪650,第二前后移动机构610与机台100连接。Referring to FIG. 6 , the conveying device 600 includes a second front-rear moving mechanism 610, a left-right moving mechanism 620, a second rotational driving mechanism 630, a lifting moving mechanism 640, and a second plate gripper 650, which are connected in sequence. Station 100 connections.
第二前后移动机构610可驱动左右移动机构620、第二旋转驱动机构630、升降移动机构640和第二平皿夹爪650沿前后方向移动,左右移动机构620可驱动第二旋转驱动机构630、升降移动机构640和第二平皿夹爪650沿左右方向移动;第二旋转驱动机构630可驱动升降移动机构640和第二平皿夹爪650转动;升降移动机构640可驱动第二平皿夹爪650升降,也即是说,第二平皿夹爪650具有前后、左右和上下方向移动以及绕竖直轴转动的功能。The second front-rear movement mechanism 610 can drive the left-right movement mechanism 620, the second rotation driving mechanism 630, the lifting movement mechanism 640 and the second plate gripper 650 to move in the front-rear direction, and the left-right movement mechanism 620 can drive the second rotation driving mechanism 630, the lifting mechanism The moving mechanism 640 and the second plate gripper 650 move in the left and right directions; the second rotational drive mechanism 630 can drive the lift movement mechanism 640 and the second plate gripper 650 to rotate; the lift movement mechanism 640 can drive the second plate gripper 650 to rise and fall, That is, the second plate gripper 650 has the functions of moving forward and backward, left and right, and up and down, and rotating around a vertical axis.
第二前后移动机构610包括相互配合的第三丝杠副、导轨和导块,第三丝杠副、导轨和导块均设于机台100上,左右移动机构620与导块、第三丝杠副的输出端连接。左右移动机构620、升降移动机构640和第二前后移动机构610的结构类似,在次不做冗余的介绍。第二旋转驱动机构630可为第三电机。The second front and rear moving mechanism 610 includes a third screw pair, a guide rail and a guide block that cooperate with each other. The third screw pair, the guide rail and the guide block are all arranged on the machine table 100. The left and right moving mechanism 620 is connected to the guide block, the third screw The output terminal of the lever pair is connected. The structures of the left-right moving mechanism 620 , the up-and-down moving mechanism 640 and the second front-rear moving mechanism 610 are similar, and will not be described redundantly here. The second rotational driving mechanism 630 may be a third motor.
上面结合附图对本发明实施例作了详细说明,但是本发明不限于上述实施例,在所属技术领域普通技术人员所具备的知识范围内,还可以在不脱离本发明 宗旨的前提下作出各种变化。The embodiments of the present invention have been described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above-mentioned embodiments, and within the scope of knowledge possessed by those of ordinary skill in the art, various Variety.

Claims (10)

  1. 血样培养检测工作站,其特征在于,包括:The blood sample culture detection workstation is characterized in that it includes:
    机台(100),所述机台(100)上设有支架(110);a machine table (100), a bracket (110) is provided on the machine table (100);
    平皿取血装置(200),所述平皿取血装置(200)包括均设于所述支架(110)上的培养瓶夹爪(210)、取血件夹爪(220)和第一平皿夹爪(230),所述培养瓶夹爪(210)和所述第一平皿夹爪(230)分别朝下和朝上设置,所述培养瓶夹爪(210)、所述取血件夹爪(220)和所述第一平皿夹爪(230)可处于由上往下依次设置状态;A plate blood taking device (200), the plate blood taking device (200) comprising a culture bottle clamping claw (210), a blood sampling piece clamping claw (220) and a first plate clamp, all of which are arranged on the support (110). Claws (230), the culture bottle clamping claw (210) and the first plate clamping claw (230) are respectively disposed downward and upward, the culture bottle clamping claw (210), the blood sampling piece clamping claw (220) and the first plate gripper (230) can be arranged in sequence from top to bottom;
    药敏纸分配器(300),所述药敏纸分配器(300)设于所述支架(110)上,所述药敏纸分配器(300)可正对所述第一平皿夹爪(230),所述药敏纸分配器(300)用于往平皿内投放药敏纸;A drug-sensitive paper dispenser (300), the drug-sensitive paper dispenser (300) is provided on the support (110), and the drug-sensitive paper dispenser (300) can face the first plate gripper ( 230), the drug-sensitive paper dispenser (300) is used to put the drug-sensitive paper into the dish;
    培养组件(400)和检测装置(500),所述培养组件(400)和所述检测装置(500)均设于所述机台(100)上;a culture assembly (400) and a detection device (500), the culture assembly (400) and the detection device (500) are both provided on the machine table (100);
    搬运装置(600),所述搬运装置(600)设于所述机台(100)上,所述搬运装置(600)可将所述平皿置于所述第一平皿夹爪(230)或所述培养组件(400)或所述检测装置(500)上。A conveying device (600), the conveying device (600) is arranged on the machine table (100), and the conveying device (600) can place the plate on the first plate gripper (230) or any other plate on the culture component (400) or the detection device (500).
  2. 根据权利要求1所述的血样培养检测工作站,其特征在于:所述支架(110)上设有沿前后方向移动的第一安装板(150),所述第一安装板(150)上连接有沿左右方向移动的第二安装板(120),所述第一平皿夹爪(230)可前后滑移地设于所述支架(110)上,且所述第一平皿夹爪(230)可转动,所述培养瓶夹爪(210)可升降地设于所述第一安装板(150)上,所述培养瓶夹爪(210)用于夹持倒置的培养瓶,所述第一安装板(150)可驱使所述培养瓶处于所述第一平皿夹爪(230)的上方,所述取血件夹爪(220)与所述第二安装板(120)连接,所述第二安装板(120)可驱使取血件正对所述培养瓶的瓶口。The blood sample culture detection workstation according to claim 1, characterized in that: the support (110) is provided with a first mounting plate (150) moving in the front-rear direction, and the first mounting plate (150) is connected with a first mounting plate (150). A second mounting plate (120) moving in the left-right direction, the first plate clamping jaws (230) can be slid back and forth on the bracket (110), and the first plate clamping jaws (230) can be Rotating, the culture bottle clamping claw (210) can be lifted and lowered on the first installation plate (150), the culture bottle clamping claw (210) is used for clamping the inverted culture bottle, the first installation The plate (150) can drive the culture bottle to be above the first plate gripper (230), and the blood collection piece gripper (220) is connected with the second mounting plate (120), the second The mounting plate (120) can drive the blood sampling member to face the bottle opening of the culture bottle.
  3. 根据权利要求2所述的血样培养检测工作站,其特征在于:所述支架(110) 上还设有第一前后移动机构(130),所述第一前后移动机构(130)的输出端上连接有载台(700),所述第一平皿夹爪(230)可转动地连接于所述载台(700)上。The blood sample culture detection workstation according to claim 2, characterized in that: the support (110) is further provided with a first forward and backward moving mechanism (130), and an output end of the first forward and backward moving mechanism (130) is connected to the There is a stage (700), and the first plate gripper (230) is rotatably connected to the stage (700).
  4. 根据权利要求3所述的血样培养检测工作站,其特征在于:所述第一平皿夹爪(230)包括载板(231)和两块支撑板(232),两块所述支撑板(232)均设于所述载板(231)上,所述载板(231)可转动地设于所述载台(700)上,两块所述支撑板(232)的上表面相对应的一侧均开设有第一限位槽(800),两个所述第一限位槽(800)的底部可抵接所述平皿的底部,两个所述第一限位槽(800)的侧壁可抵接所述平皿的侧壁。The blood sample culture detection workstation according to claim 3, characterized in that: the first plate gripper (230) comprises a carrier plate (231) and two support plates (232), and the two support plates (232) Both are arranged on the carrier plate (231), the carrier plate (231) is rotatably arranged on the carrier platform (700), and the upper surfaces of the two support plates (232) correspond to one side First limit grooves (800) are opened in both, the bottoms of the two first limit grooves (800) can abut the bottom of the plate, and the side walls of the two first limit grooves (800) can abut against the side wall of the plate.
  5. 根据权利要求3或4所述的血样培养检测工作站,其特征在于:所述第一前后移动机构(130)包括第一直线驱动机构(131)以及相互配合的第一滑轨(132)和第一滑块,所述第一滑轨(132)沿前后方向延伸并与所述支架(110)连接,所述载台(700)与所述第一滑块连接,所述第一直线驱动机构(131)的输出端与所述第一滑块或所述载台(700)连接。The blood sample culture detection workstation according to claim 3 or 4, wherein the first forward and backward moving mechanism (130) comprises a first linear drive mechanism (131) and a first sliding rail (132) and a first sliding rail (132) that cooperate with each other. A first sliding block, the first sliding rail (132) extends in the front-rear direction and is connected with the bracket (110), the carrier (700) is connected with the first sliding block, the first straight line The output end of the driving mechanism (131) is connected with the first sliding block or the stage (700).
  6. 根据权利要求5所述的血样培养检测工作站,其特征在于:所述支架(110)在对应所述第一滑轨(132)上方的区域设有开盖机构(900),所述开盖机构(900)包括可升降的提升块(910),所述提升块(910)的前侧壁上设有用于收纳所述平皿的第一收纳槽(911),所述第一收纳槽(911)的底部设有可供所述平皿的盒体和第一平皿夹爪(230)伸进的第一避让槽,所述第一收纳槽(911)的底壁可抵在所述平皿的盖子的下端面上。The blood sample culture detection workstation according to claim 5, characterized in that: the bracket (110) is provided with a cover opening mechanism (900) in an area corresponding to the upper part of the first slide rail (132), and the cover opening mechanism (900) includes a lifting block (910) that can be raised and lowered, a first receiving groove (911) for receiving the plate is provided on the front side wall of the lifting block (910), and the first receiving groove (911) The bottom of the plate is provided with a first escape groove into which the box body of the plate and the first plate jaw (230) can extend, and the bottom wall of the first receiving groove (911) can abut against the cover of the plate. on the lower end surface.
  7. 根据权利要求6所述的血样培养检测工作站,其特征在于:所述开盖机构(900)还包括凸轮顶升机构(920)以及相互配合的第二滑轨(930)和第二滑块(940),所述第二滑轨(930)设于所述机台(100)上且沿上下方向延伸,所述提升块(910)与所述第二滑块(940)连接,所述凸轮顶升机构(920)设于所述机台(100)上且所述凸轮顶升机构(920)的输出端与所述提升块(910)或所述第二滑块(940)铰接。The blood sample culture detection workstation according to claim 6, wherein the cover opening mechanism (900) further comprises a cam jacking mechanism (920) and a second sliding rail (930) and a second sliding block (930) that cooperate with each other. 940), the second sliding rail (930) is provided on the machine table (100) and extends in the up-down direction, the lifting block (910) is connected with the second sliding block (940), the cam The jacking mechanism (920) is arranged on the machine table (100), and the output end of the cam jacking mechanism (920) is hinged with the lifting block (910) or the second sliding block (940).
  8. 根据权利要求1所述的血样培养检测工作站,其特征在于:所述检测装置(500)包括设于所述机台(100)上的支撑架(510)以及朝上设于所述支撑架(510)上的摄像模组(520),所述支撑架(510)在对应所述摄像模组(520)上方的区域设有托板(511),所述托板(511)上设有限位所述平皿的第二限位槽,所述第二限位槽的槽底设有观察孔。The blood sample culture detection workstation according to claim 1, characterized in that: the detection device (500) comprises a support frame (510) disposed on the machine table (100) and a support frame (510) disposed upwardly on the support frame (510). The camera module (520) on the 510), the support frame (510) is provided with a support plate (511) in the area corresponding to the upper part of the camera module (520), and the support plate (511) is provided with a limit The second limiting groove of the plate is provided with an observation hole at the bottom of the second limiting groove.
  9. 根据权利要求8所述的血样培养检测工作站,其特征在于:所述托板(511)在对应所述第二限位槽周侧的区域设有光源(530)。The blood sample culture detection workstation according to claim 8, characterized in that: a light source (530) is provided on the support plate (511) in a region corresponding to the peripheral side of the second limiting groove.
  10. 根据权利要求1所述的血样培养检测工作站,其特征在于:所述搬运装置(600)包括依次连接的第二前后移动机构(610)、左右移动机构(620)、第二旋转驱动机构(630)、升降移动机构(640)和第二平皿夹爪(650),所述第二前后移动机构(610)与所述机台(100)连接。The blood sample culture detection workstation according to claim 1, characterized in that: the transport device (600) comprises a second forward and backward movement mechanism (610), a left and right movement mechanism (620), and a second rotational drive mechanism (630) connected in sequence. ), a lifting and moving mechanism (640) and a second plate gripper (650), and the second forward and backward moving mechanism (610) is connected to the machine table (100).
PCT/CN2021/128027 2021-04-19 2021-11-02 Blood sample cultivation and testing workstation WO2022222414A1 (en)

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