WO2022172708A1 - Syringe and syringe barrel - Google Patents

Syringe and syringe barrel Download PDF

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Publication number
WO2022172708A1
WO2022172708A1 PCT/JP2022/001744 JP2022001744W WO2022172708A1 WO 2022172708 A1 WO2022172708 A1 WO 2022172708A1 JP 2022001744 W JP2022001744 W JP 2022001744W WO 2022172708 A1 WO2022172708 A1 WO 2022172708A1
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WO
WIPO (PCT)
Prior art keywords
needle tube
diameter
small
syringe
diameter portion
Prior art date
Application number
PCT/JP2022/001744
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French (fr)
Japanese (ja)
Inventor
勇輝 間中
Original Assignee
株式会社トップ
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Publication date
Application filed by 株式会社トップ filed Critical 株式会社トップ
Priority to JP2022581280A priority Critical patent/JPWO2022172708A1/ja
Publication of WO2022172708A1 publication Critical patent/WO2022172708A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub

Definitions

  • the present invention relates to a syringe and a syringe outer cylinder used for administering a drug solution to a human body or the like.
  • some relatively small-capacity syringes used for administering vaccines have a needle tube directly fixed to the outer cylinder (barrel).
  • Such needle-equipped syringes have the advantage of having less dead space than syringes to which the needle tube is connected via a luer connector.
  • the needle-equipped syringe has the advantage that the amount of liquid medicine remaining in the syringe is small when the pusher (plunger) inserted in the outer cylinder is completely pushed out. can be used for
  • the needle tube is fixed to the outer cylinder by inserting the rear end of the needle tube into the needle tube insertion part which is a part of the hole provided at the tip of the outer cylinder and pouring an adhesive between the two. It is done by gluing. Further, positioning of the needle tube in the axial direction is performed by providing a step at the rear end of the needle tube insertion portion (see, for example, Patent Document 1).
  • the rear end portion of the needle tube insertion portion is a region extending in a plurality of axial and radial directions of the outer cylinder. Since it is located in a region with poor properties, that is, in a region where sink marks and voids are likely to occur during resin molding, there is a problem that molding defects tend to occur.
  • the conventional needle-equipped syringe not only has poor assembling properties, but also has low productivity due to a decrease in yield.
  • the syringe of the present invention includes a needle tube and an outer tube to which the needle tube is fixed, the outer tube including a bottomed cylindrical outer tube main body portion including a bottom portion and a cylindrical portion; is fixed, a needle tube insertion portion provided in the protrusion and into which the needle tube is inserted, and a flow passage that communicates the inner space of the outer cylinder main body and the needle tube insertion portion,
  • the flow path is provided at a position connected to the needle tube insertion portion, and is provided so as to connect a small diameter portion having a smaller diameter or a narrower width than the outer diameter of the needle tube, and an inner space of the outer cylinder main body portion and the small diameter portion.
  • a large-diameter portion having a larger diameter or width than the small-diameter portion, and the small-diameter portion is provided closer to the tip side than the tip side surface of the bottom portion.
  • the syringe outer cylinder of the present invention includes a bottomed cylindrical outer cylinder main body portion composed of a bottom portion and a cylindrical portion, a projecting portion projecting from the bottom portion and to which a needle tube is fixed, and a needle tube fixed to the projecting portion. , a needle tube insertion portion into which the needle tube is inserted, and a flow passage that communicates the inner space of the outer cylinder main body portion and the needle tube insertion portion, and the flow passage is provided at a position connected to the needle tube insertion portion.
  • a small-diameter portion having a smaller diameter or a narrower width than the outer diameter of the needle tube; and a large-diameter portion having a larger diameter or a wider width than the small-diameter portion, provided so as to connect the inner space of the outer cylinder main body portion and the small-diameter portion. , wherein the small-diameter portion is provided closer to the tip side than the tip side surface of the bottom portion.
  • the wall thickness in the vicinity of the small-diameter portion is appropriately reduced by the large-diameter portion, the cooling rate in the vicinity of the small-diameter portion and the needle tube insertion portion during resin molding is improved, and the outer periphery of the tip side and the bottom portion of the projecting portion is improved. Since it is possible to suppress the effect of tension due to the resin whose temperature has dropped earlier on the side, it is possible to prevent molding defects such as sink marks and voids that occur in the small diameter portion and the needle tube insertion portion. As a result, it is possible to prevent problems from occurring in fixing the needle tube to the outer cylinder, so that it is possible to improve the ease of assembly and yield, and increase the productivity of the syringe.
  • the large diameter portion is configured to form a step with the small diameter portion.
  • the large-diameter portion has a portion in which the diameter expansion ratio or width expansion ratio decreases toward the rear end side.
  • This also makes it possible to reduce the thickness in the vicinity of the small-diameter portion to a greater extent, so that molding defects such as sink marks and voids that occur in the small-diameter portion and the needle tube insertion portion can be more effectively prevented.
  • the bottom portion is configured so that the thickness gradually decreases toward the large diameter portion side.
  • the bottom portion has a first tapered surface connected to the large diameter portion and a second tapered surface on the outer peripheral side of the first tapered surface on the rear end side surface.
  • the taper angle is preferably larger than the taper angle of the second tapered surface.
  • the tip surface of the gasket at the tip of the plunger can be properly brought into close contact with the rear end side surface, and the gasket can be deformed so that part of the tip surface of the gasket enters the large diameter portion. It is possible to further reduce the dead space in the outer cylinder, and to efficiently use the liquid medicine or the like administered to the human body or the like.
  • FIG. 1A is a front view of a syringe according to one embodiment of the present invention
  • FIG. B is a cross-sectional view taken along line II of FIG. 1A.
  • A is a front view of a gasket.
  • B is a cross-sectional view taken along line II-II of FIG. 2A.
  • FIG. 4 is an enlarged cross-sectional view showing the periphery of the bottom and protrusions;
  • FIG. 4 is an enlarged cross-sectional view showing the bottom portion and the periphery of the projecting portion in a state where the pusher is fully pushed;
  • FIG. 1A is a front view of a syringe 1 according to one embodiment of the present invention
  • FIG. 1B is a cross-sectional view taken along line II of FIG. 1A.
  • the syringe 1 includes a needle tube 10, an outer cylinder (barrel) 20 to which the needle tube 10 is fixed, a plunger (plunger) 30 inserted into the outer cylinder 20, and a gasket 40 attached to the tip of the plunger. , is equipped with
  • the needle tube 10 is a part that is punctured into the human body or the like.
  • the needle tube 10 is made of an appropriate metal such as stainless steel, and has a blade surface 11 formed at its distal end to sharpen the tip of the needle.
  • the size of the needle tube 10 is not particularly limited, and for example, 16 to 33 gauge (outer diameter: 1.7 to 0.2 mm) defined by ISO9626 can be used.
  • the shape of the needle tip of the needle tube 10 is not particularly limited, and may be one subjected to lancet processing or backcut processing. Further, the needle tube 10 may have inner and outer diameters that change in the axial direction.
  • the outer cylinder 20 is a part that internally accommodates a liquid medicine or the like to be administered to the human body.
  • the outer cylinder 20 is made of an appropriate transparent or translucent resin such as polypropylene, acrylonitrile-butadiene-styrene (ABS) resin, polycarbonate, or the like.
  • the outer cylinder 20 includes a bottomed cylindrical outer cylinder main body portion 21 that defines an internal space for accommodating a liquid medicine or the like, a cylindrical protruding portion 22 that protrudes from the distal end portion of the outer cylinder main body portion 21, have.
  • the outer tube main body 21 is composed of a cylindrical tube 21a having a substantially constant inner and outer diameter, and a disk-shaped bottom 21b that closes the tip of the tube 21a.
  • a rear end portion of the outer peripheral surface 21a1 of the cylindrical portion 21a is provided with an elliptical flange portion 21c protruding toward the outer peripheral side in plan view.
  • the flange portion 21c is a portion where the user of the syringe 1 puts fingers (for example, the index finger and the middle finger), and a tip side surface 21c1 of the flange portion 21c has a C-shaped non-slip surface in plan view.
  • a protrusion 21C2 is provided.
  • Flat portions 21c3 are provided on the front and rear end surfaces of the flange portion 21c so that the syringe 1 can be stably placed on a desk or the like in a horizontal state.
  • the outer peripheral surface 21a1 of the cylindrical portion 21a is also provided with a scale (not shown) that indicates the amount of the contained chemical solution.
  • a rear end portion of the inner peripheral surface 21a2 of the tubular portion 21a is provided with a projection 21d continuous in the circumferential direction. This protrusion 21d is for preventing the plunger 30 and the gasket 40 from easily coming off from the outer cylinder 20. As shown in FIG.
  • a projecting portion 22 protrudes toward the tip side from the central portion of the tip side surface 21b1 of the bottom portion 21b.
  • a cylindrical collar 23 for reinforcing the protrusion 22 and four trapezoidal ribs 24 are provided around the protrusion 22 .
  • the collar 23 is provided so as to surround the outer periphery of the proximal end of the projecting portion 22 .
  • the ribs 24 are circumferentially evenly spaced between the protrusion 22 and the collar 23 and are connected to the protrusion 22 , the bottom 21 b and the collar 23 .
  • an engaging concave portion 24b is provided on an end face 24a on the outer peripheral side of the rib 24 so as to be engaged with a cap (not shown) for protecting the needle.
  • the productivity of the syringe 1 is improved by devising the shapes of the bottom portion 21b and the projecting portion 22 of the outer cylinder 20 .
  • the details of the shapes of the bottom portion 21b and the projecting portion 22 will be described later.
  • the pusher 30 is inserted into the outer cylinder 20 through an opening on the rear end side of the outer cylinder 20, and is pressed when administering a liquid medicine or the like.
  • the pusher 30 is a rod-shaped member having a cross-shaped cross section, and is made of an appropriate resin such as polystyrene, polypropylene, polycarbonate, or the like.
  • a stepped columnar engaging portion 31 with a small diameter on the base end side that engages with the gasket 40, a flange-like pressing portion 32 that contacts and presses the gasket 40 during pressing operation is provided.
  • a disk-shaped force receiving portion 33 is provided at the rear end portion of the pusher 30 to receive the pressing force of the user's finger (for example, thumb) during pressing operation.
  • the gasket 40 seals the rear end side of the outer cylinder 20, and is made of a material having suitable elasticity such as thermoplastic elastomer, silicone rubber and butadiene rubber.
  • 2A is a front view of the gasket 40
  • FIG. 2B is a cross-sectional view taken along line II-II of FIG. 2A.
  • the gasket 40 is configured in a bottomed cylindrical shape with an open rear end side.
  • the outer peripheral surface 41 of the gasket 40 has a shape in which an intermediate portion 41a in the axial direction is constricted. It slides on the inner peripheral surface 21a2 of the portion 21a.
  • the outer diameter of the intermediate portion 41a is set smaller than the inner diameter of the cylindrical portion 21a. Further, the outer diameters of the leading end side sliding portion 41b and the rear end side sliding portion 41c are set larger than the inner diameter of the cylindrical portion 21a. Thus, by providing the front end side sliding portion 41b and the rear end side sliding portion 41c, it is possible to achieve both sealing performance and slidability.
  • the outer diameter of the intermediate portion 41a may be set substantially equal to the inner diameter of the cylindrical portion 21a. Since the outer diameter of the gasket 40 is reduced as a whole due to the compressive force received from the tubular portion 21a, the intermediate portion 41a and the inner peripheral surface 21a2 of the tubular portion 21a can be prevented from contacting each other in this case as well.
  • the outer diameters of the front end side sliding portion 41b and the rear end side sliding portion 41c may be set substantially the same, or may be set to different outer diameters in anticipation of deformation after molding.
  • a tip surface 42 of the gasket 40 is configured in a truncated cone shape, and a dome-shaped concave portion 42a is provided in the central portion.
  • the taper angle of the tip surface 42 is set to about 160°.
  • the dose of the liquid medicine is measured by reading the scale corresponding to the tip position of the contact surface with the inner peripheral surface 21a2 of the tip side sliding portion 41b, but the protrusion amount of the tip face 42 is large. and the vicinity of the scale becomes dark, making it difficult to read. In this embodiment, such a problem is prevented by reducing the protrusion amount of the tip surface.
  • the inner peripheral surface 43 of the gasket 40 is configured such that the inner diameter on the rear end side is smaller than that on the front end side so as to engage with the engaging portion 31 of the pusher 30 .
  • a tapered introduction portion 43a is provided at the rear end portion of the inner peripheral surface 43 so that the engagement portion 31 can be easily inserted.
  • the rear end surface 44 of the gasket 40 is formed in a planar shape substantially orthogonal to the axis, and is stably brought into contact with and pressed by the pressing portion 32 of the pusher 30 .
  • FIG. 3 is a cross-sectional view taken along the line II of FIG. 1A, showing an enlarged view of the periphery of the bottom portion 21b and the protruding portion 22.
  • FIG. The projecting portion 22 has a tapered enlarged diameter portion 22a at the base end portion, the outer diameter of which gradually increases toward the rear end side. ing.
  • a needle tube insertion portion 25 which is a hole into which the rear end side of the needle tube 10 is inserted and fixed, is provided inside the protruding portion 22.
  • the needle tube insertion portion 25 is axially bored from the distal end surface 22b of the projecting portion 22, and is composed of a needle tube support portion 25a on the rear end side and an adhesive agent accommodating portion 25b on the distal end side.
  • the needle tube support portion 25a has an inner peripheral surface 25a1 that is slightly larger than the outer diameter of the needle tube 10 and has a substantially constant inner diameter in the axial direction, and has a stepped rear end surface 25a2. That is, the needle tube support portion 25a holds the needle tube 10 in a posture along the axial center of the outer cylinder 20 by means of the inner peripheral surface 25a1, and brings the needle tube 10 to the axis by bringing the rear end surface 25a2 into contact with the rear end surface 12 of the needle tube 10. It is configured for positioning in a direction.
  • the adhesive containing portion 25b is tapered such that the inner diameter gradually increases from the needle tube supporting portion 25a toward the distal end side, and forms a filling space in which the adhesive 50 is filled between the needle tube 10 and the adhesive accommodating portion 25b.
  • two circumferentially continuous grooves 25b1 are provided in the adhesive containing portion 25b so that the cured adhesive 50 engages with the grooves 25b1.
  • the adhesive containing portion 25b may be subjected to appropriate surface treatment or the like to enhance the adhesiveness.
  • a flow passage 26 that communicates the inner space of the needle tube insertion portion 25 and the outer cylinder main body portion 21 is provided inside the projecting portion 22 and the bottom portion 21b.
  • the flow passage 26 is a passage through which a liquid medicine or the like flows, and is composed of a small diameter portion 26a on the distal end side connected to the needle tube insertion portion 25 and a large diameter portion 26b connecting the inner space of the outer cylinder main body portion 21 and the small diameter portion 26a. It is configured.
  • the small-diameter portion 26a has an inner diameter that is smaller than the outer diameter of the needle tube 10 and larger than the inner diameter of the needle tube 10, and is set to have a substantially constant inner diameter in the axial direction.
  • the needle tube support portion 25a is formed with a rear end surface 25a2, and the needle tube 10 can be positioned in the axial direction.
  • the large-diameter portion 26b has an inner diameter larger than that of the small-diameter portion 26a as a whole, and has a stepped tip surface 26b1.
  • the large-diameter portion 26b further includes a first rounded portion 26b2 whose diameter gradually increases toward the rear end side from the front end surface 26b1, and whose diameter expansion rate gradually decreases toward the rear end side, and a first rounded portion 26b2.
  • a tapered portion 26b3 that gradually expands in diameter toward the end side
  • a second rounded portion 26b4 that gradually expands in diameter from the tapered portion 26b3 toward the rear end side and whose diameter expansion rate gradually increases toward the rear end side.
  • the large-diameter portion 26b serves not only as a passage for liquid medicine, etc., but also to prevent molding defects such as sink marks and voids that occur in the needle tube support portion 25a, the small-diameter portion 26a, and their vicinity during resin molding of the outer cylinder 20. Configured to work as a steal.
  • the needle tube support portion 25a and the small-diameter portion 26a are portions formed by a core pin of a resin mold, and are regions with poorer heat dissipation than the tip side of the projecting portion 22 and the outer peripheral side of the bottom portion 21b. Therefore, around the needle tube support portion 25a and the small-diameter portion 26a, in the cooling step after filling the resin in the mold, the resin on the front end side of the protruding portion 22 and the outer peripheral side of the bottom portion 21b whose temperature has decreased earlier is pulled. As a result, sink marks, voids, and the like are likely to occur, and there is a possibility that the needle tube support portion 25a and the small-diameter portion 26a will not be formed into appropriate dimensions and shapes.
  • the small-diameter portion 26a and the large-diameter portion 26b are arranged so that the front end surface 26b1 of the large-diameter portion 26b (in other words, the rear end of the small-diameter portion 26a) is located on the front end side of the front end side surface 21b1 of the bottom portion 21b.
  • the needle tube support portion 25a and the small diameter portion 26a are formed to have appropriate dimensions and shapes, so that the needle tube can be appropriately positioned and fixed to the outer cylinder. That is, the syringe 1 of the present embodiment has both good assembling property and high yield, and is excellent in productivity.
  • a step is provided between the small diameter portion 26a and the large diameter portion 26b, and a portion in which the diameter expansion rate gradually decreases toward the rear end side is provided in the large diameter portion 26b. It is possible to prevent molding defects more effectively by largely hollowing out the vicinity. Furthermore, by providing the enlarged diameter portion 22a and the second rounded portion 26b4 in correspondence with each other, it is possible to reduce the change in thickness in the connecting region between the projecting portion 22 and the bottom portion 21b, thereby more effectively preventing defective molding. making it possible to
  • a tip side surface 21b1 of the bottom portion 21b is formed in a planar shape substantially orthogonal to the axial center of the outer cylinder 20.
  • the rear end side surface 21b2 of the bottom portion 21b facing the inner space of the outer cylinder main body portion 21 is tapered such that the thickness in the axial direction gradually decreases from the outer peripheral side toward the axial center side (large diameter portion 26b side). It is In the present embodiment, by configuring the bottom portion 21b in this manner, the thickness of the connecting region between the protruding portion 22 and the bottom portion 21b can be reduced, making it possible to prevent molding defects more effectively.
  • the rear end side surface 21b2 of the bottom portion 21b is divided into two types: a first tapered surface 21b2a connected to the large diameter portion 26b and a second tapered surface 21b2b on the outer peripheral side of the first tapered surface 21b2a.
  • the tapered surface and the taper angle of the first tapered surface 21b2a are set larger than the taper angle of the second tapered surface 21b2b to increase the adhesion between the gasket 40 and the tip surface 42 and reduce the dead space. I am trying to
  • FIG. 4 is a cross-sectional view taken along the line II of FIG. 1A, showing an enlarged view of the periphery of the bottom portion 21b and the protruding portion 22 when the pusher 30 is fully pushed.
  • the front end surface 42 of the gasket 40 is in a state of being in proper contact with the rear end side surface 21b2 of the bottom portion 21b.
  • the taper angle of the first tapered surface 21b2a is set to about 174°
  • the taper angle of the second tapered surface 21b2b is set to about 145° with respect to the taper angle of the tip surface 42 of the gasket 40 of about 160°.
  • the peripheral edge of the recess 42a of the tip surface 42 of the gasket 40 is inserted into the large diameter portion 26b.
  • the dead space in the outer cylinder 20 is further reduced.
  • the tip surface 42 of the gasket 40 can easily enter the large diameter portion 26b.
  • the rear end side surface 21b2 and the large diameter portion 26b of the bottom portion 21b are not provided with a portion projecting toward the rear end side or a portion configured in a tapered shape in the opposite direction. It is possible to smoothly guide air bubbles generated during suction toward the small-diameter portion 26 a and discharge them from the tip of the needle tube 10 .
  • the cross-sectional shapes of the needle tube insertion portion 25 and the flow path 26 are not limited to circular shapes, and various shapes such as elliptical shapes and polygonal shapes can be adopted.
  • the small-diameter portion 26a may be configured to be narrower than the outer diameter of the needle tube 10 in any direction perpendicular to the axis.
  • the large diameter portion 26b may be wider than the inner diameter of the small diameter portion 26a in any direction perpendicular to the axis, and the width expansion ratio is reduced in any direction perpendicular to the axis. It is preferable to have a portion that
  • the tip surface 26b1 of the large diameter portion 26b may be tapered, or the tip surface 26b1 may be omitted and the first rounded portion 26b2 may be connected to the small diameter portion 26a.
  • the rear end side surface 21b2 of the bottom portion 21b may be composed of one tapered surface, or may be composed of a curved surface. Further, the tip side surface 21b1 of the bottom portion 21b may be tapered.
  • the adhesive containing portion 25b may be omitted from the needle tube insertion portion 25, and the needle tube 10 may be fixed to the outer cylinder 20 by welding or insert molding.
  • the syringe and syringe outer cylinder of the present invention are not limited to the above-described embodiments, and various modifications can be made without departing from the gist of the present invention. It is of course possible to add
  • the shape and arrangement of each part of the syringe 1 are not limited to the shapes and arrangements shown in the above-described embodiments, and various known shapes and arrangements can be adopted.

Abstract

Provided are a syringe and a syringe barrel that can raise productivity. The syringe 1 according to the present invention comprises a needle tube 10 and a barrel 20 to which the needle tube 10 is fixed. The barrel 20 has: a barrel body 21 that is in the shape of a bottomed cylinder and that is composed of a bottom portion 21b and a cylinder portion 21a; a projecting portion 22, which is installed in a protruding manner on the bottom portion 21b and to which the needle tube 10 is fixed; a needle tube insertion portion 25, which is provided on the projecting portion 22 and into which the needle tube 10 is inserted; and a flow passage 26 through which the interior space of the barrel body 21 and the needle tube insertion portion 25 communicate. The flow passage 26 has a small-diameter portion 26a that is provided at a position connecting to the needle tube insertion portion 25 and that is smaller in diameter or narrower than the outside diameter of the needle tube 10, and a large-diameter portion 26b that is provided so as to connect the interior space of the barrel body 21 and the small-diameter portion 26a and that is larger in diameter or wider than the small-diameter portion 26a. The small-diameter portion 26a is provided further toward the distal-end side than a distal-end-side surface 21b1 of the bottom portion 21b.

Description

シリンジおよびシリンジ用外筒Syringes and barrels for syringes
　本発明は、人体等への薬液等の投与に使用されるシリンジおよびシリンジ用外筒に関する。 The present invention relates to a syringe and a syringe outer cylinder used for administering a drug solution to a human body or the like.
　従来、ワクチン投与等に使用される比較的容量の小さいシリンジには、針管が直接外筒（バレル）に固定されているものが存在する。このような針付きシリンジは、ルアーコネクタを介して針管が接続されるシリンジと比較してデッドスペースが少ないという利点を有している。 Conventionally, some relatively small-capacity syringes used for administering vaccines have a needle tube directly fixed to the outer cylinder (barrel). Such needle-equipped syringes have the advantage of having less dead space than syringes to which the needle tube is connected via a luer connector.
　すなわち、針付きシリンジは、外筒内に挿入された押し子（プランジャ）を押し切った状態でシリンジ内に残存する薬液等の量が少ないという利点を有しており、薬液等を無駄なく効率的に使用することが可能となっている。 That is, the needle-equipped syringe has the advantage that the amount of liquid medicine remaining in the syringe is small when the pusher (plunger) inserted in the outer cylinder is completely pushed out. can be used for
　一般に、針付きシリンジにおける外筒への針管の固定は、外筒先端部に設けた孔の一部である針管挿入部に針管の後端側を挿入し、両者の間に接着剤を流し込んで接着することにより行われる。また、針管の軸方向における位置決めは、針管挿入部の後端に段差を設けることにより行われる（例えば、特許文献１参照）。 In general, in a syringe with a needle, the needle tube is fixed to the outer cylinder by inserting the rear end of the needle tube into the needle tube insertion part which is a part of the hole provided at the tip of the outer cylinder and pouring an adhesive between the two. It is done by gluing. Further, positioning of the needle tube in the axial direction is performed by providing a step at the rear end of the needle tube insertion portion (see, for example, Patent Document 1).
特開２０１６－１６３６４２号公報JP 2016-163642 A
　しかしながら、一般に外筒は樹脂から構成されるところ、針管挿入部の後端部分は、外筒の軸方向および放射方向の複数方向に延在する領域であり、且つ筒状の部材の内側の放熱性の悪い領域、すなわち樹脂成形時にヒケやボイドが発生しやすい領域に位置することとなるため、成形不良が生じやすいという問題があった。 However, since the outer cylinder is generally made of resin, the rear end portion of the needle tube insertion portion is a region extending in a plurality of axial and radial directions of the outer cylinder. Since it is located in a region with poor properties, that is, in a region where sink marks and voids are likely to occur during resin molding, there is a problem that molding defects tend to occur.
　針管挿入部の後端部分に成形不良が生じると、針管を適切に位置決めして外筒に固定することが困難となる。このため、従来の針付きシリンジは、組み立て性が悪いだけでなく、歩留りの低下により生産性も低いものとなっていた。 If a molding defect occurs in the rear end portion of the needle tube insertion portion, it becomes difficult to properly position the needle tube and fix it to the outer cylinder. For this reason, the conventional needle-equipped syringe not only has poor assembling properties, but also has low productivity due to a decrease in yield.
　本発明は、このような実情に鑑み、生産性を高めることが可能なシリンジおよびシリンジ用外筒を提供しようとするものである。 In view of such circumstances, it is an object of the present invention to provide a syringe and a syringe outer cylinder capable of increasing productivity.
　本発明のシリンジは、針管および前記針管が固定される外筒を備え、前記外筒は、底部および筒部からなる有底筒状の外筒本体部と、前記底部に突設され、前記針管が固定される突出部と、前記突出部に設けられ、前記針管が挿入される針管挿入部と、前記外筒本体部の内部空間と前記針管挿入部を連通する流通路と、を有し、前記流通路は、前記針管挿入部に繋がる位置に設けられ、前記針管の外径よりも小径または幅狭の小径部と、前記外筒本体部の内部空間と前記小径部を繋ぐように設けられ、前記小径部よりも大径または幅広の大径部と、を有し、前記小径部は、前記底部の先端側面よりも先端側に設けられることを特徴とする。 The syringe of the present invention includes a needle tube and an outer tube to which the needle tube is fixed, the outer tube including a bottomed cylindrical outer tube main body portion including a bottom portion and a cylindrical portion; is fixed, a needle tube insertion portion provided in the protrusion and into which the needle tube is inserted, and a flow passage that communicates the inner space of the outer cylinder main body and the needle tube insertion portion, The flow path is provided at a position connected to the needle tube insertion portion, and is provided so as to connect a small diameter portion having a smaller diameter or a narrower width than the outer diameter of the needle tube, and an inner space of the outer cylinder main body portion and the small diameter portion. , and a large-diameter portion having a larger diameter or width than the small-diameter portion, and the small-diameter portion is provided closer to the tip side than the tip side surface of the bottom portion.
　また、本発明のシリンジ用外筒は、底部および筒部からなる有底筒状の外筒本体部と、前記底部に突設され、針管が固定される突出部と、前記突出部に設けられ、前記針管が挿入される針管挿入部と、前記外筒本体部の内部空間と前記針管挿入部を連通する流通路と、を備え、前記流通路は、前記針管挿入部に繋がる位置に設けられ、前記針管の外径よりも小径または幅狭の小径部と、前記外筒本体部の内部空間と前記小径部を繋ぐように設けられ、前記小径部よりも大径または幅広の大径部と、を有し、前記小径部は、前記底部の先端側面よりも先端側に設けられることを特徴とする。 Further, the syringe outer cylinder of the present invention includes a bottomed cylindrical outer cylinder main body portion composed of a bottom portion and a cylindrical portion, a projecting portion projecting from the bottom portion and to which a needle tube is fixed, and a needle tube fixed to the projecting portion. , a needle tube insertion portion into which the needle tube is inserted, and a flow passage that communicates the inner space of the outer cylinder main body portion and the needle tube insertion portion, and the flow passage is provided at a position connected to the needle tube insertion portion. a small-diameter portion having a smaller diameter or a narrower width than the outer diameter of the needle tube; and a large-diameter portion having a larger diameter or a wider width than the small-diameter portion, provided so as to connect the inner space of the outer cylinder main body portion and the small-diameter portion. , wherein the small-diameter portion is provided closer to the tip side than the tip side surface of the bottom portion.
　本発明によれば、大径部によって小径部近傍の肉厚を適宜に低減し、樹脂成形時における小径部および針管挿入部近傍の冷却速度を向上させると共に、突出部の先端側および底部の外周側において先に温度が低下した樹脂による引っ張りの影響を抑制することが可能となるため、小径部および針管挿入部に生じるヒケやボイド等の成形不良を防止することができる。これにより、針管の外筒への固定に不具合が生じるのを防止することが可能となるため、組み立て性および歩留りを向上させ、シリンジの生産性を高めることができる。 According to the present invention, the wall thickness in the vicinity of the small-diameter portion is appropriately reduced by the large-diameter portion, the cooling rate in the vicinity of the small-diameter portion and the needle tube insertion portion during resin molding is improved, and the outer periphery of the tip side and the bottom portion of the projecting portion is improved. Since it is possible to suppress the effect of tension due to the resin whose temperature has dropped earlier on the side, it is possible to prevent molding defects such as sink marks and voids that occur in the small diameter portion and the needle tube insertion portion. As a result, it is possible to prevent problems from occurring in fixing the needle tube to the outer cylinder, so that it is possible to improve the ease of assembly and yield, and increase the productivity of the syringe.
　また、本発明において、前記大径部は、前記小径部との間に段差を形成するように構成されることが好ましい。 Further, in the present invention, it is preferable that the large diameter portion is configured to form a step with the small diameter portion.
　これによれば、小径部の近傍をより大きく肉抜きすることが可能となるため、小径部および針管挿入部に生じるヒケやボイド等の成形不良をより効果的に防止することができる。 According to this, it is possible to reduce the thickness in the vicinity of the small diameter portion to a greater extent, so it is possible to more effectively prevent molding defects such as sink marks and voids that occur in the small diameter portion and the needle tube insertion portion.
　また、本発明において、前記大径部は、後端側に向けて拡径率または拡幅率が減少する部分を有することが好ましい。 In addition, in the present invention, it is preferable that the large-diameter portion has a portion in which the diameter expansion ratio or width expansion ratio decreases toward the rear end side.
　これによっても、小径部の近傍をより大きく肉抜きすることが可能となるため、小径部および針管挿入部に生じるヒケやボイド等の成形不良をより効果的に防止することができる。 This also makes it possible to reduce the thickness in the vicinity of the small-diameter portion to a greater extent, so that molding defects such as sink marks and voids that occur in the small-diameter portion and the needle tube insertion portion can be more effectively prevented.
　また、本発明において、前記底部は、前記大径部側に向けて厚みが漸次減少するように構成されることが好ましい。 Further, in the present invention, it is preferable that the bottom portion is configured so that the thickness gradually decreases toward the large diameter portion side.
　これによれば、突出部と底部の接続領域における肉厚を低減し、小径部および針管挿入部に生じるヒケやボイド等の成形不良をより効果的に防止することができる。 According to this, it is possible to reduce the thickness of the connection area between the projecting portion and the bottom portion, and to more effectively prevent molding defects such as sink marks and voids that occur in the small diameter portion and the needle tube insertion portion.
　また、本発明において、前記底部は、前記大径部に繋がる第１テーパ面、および前記第１テーパ面よりも外周側の第２テーパ面を後端側面に有し、前記第１テーパ面のテーパ角度は、前記第２テーパ面のテーパ角度よりも大きいことが好ましい。 Further, in the present invention, the bottom portion has a first tapered surface connected to the large diameter portion and a second tapered surface on the outer peripheral side of the first tapered surface on the rear end side surface. The taper angle is preferably larger than the taper angle of the second tapered surface.
　これによれば、押し子先端のガスケットの先端面を後端側面に適切に密着させると共に、ガスケットの先端面の一部が大径部内に入り込むようにガスケットを変形させることが可能となるため、外筒内のデッドスペースをさらに削減し、人体等に投与される薬液等を効率的に使用することができる。 According to this, the tip surface of the gasket at the tip of the plunger can be properly brought into close contact with the rear end side surface, and the gasket can be deformed so that part of the tip surface of the gasket enters the large diameter portion. It is possible to further reduce the dead space in the outer cylinder, and to efficiently use the liquid medicine or the like administered to the human body or the like.
　本発明のシリンジおよびシリンジ用外筒によれば、生産性を高めることが可能という優れた効果を奏し得る。 According to the syringe and syringe outer cylinder of the present invention, it is possible to achieve an excellent effect of being able to increase productivity.
Ａは、本発明の一実施形態に係るシリンジの正面図である。Ｂは、図１ＡのＩ－Ｉ線断面図である。1A is a front view of a syringe according to one embodiment of the present invention; FIG. B is a cross-sectional view taken along line II of FIG. 1A. Ａは、ガスケットの正面図である。Ｂは、図２ＡのＩＩ－ＩＩ線断面図である。A is a front view of a gasket. B is a cross-sectional view taken along line II-II of FIG. 2A. 底部および突出部の周辺を拡大して示した断面図である。FIG. 4 is an enlarged cross-sectional view showing the periphery of the bottom and protrusions; 押し子を押し切った状態での底部および突出部周辺を拡大して示した断面図である。FIG. 4 is an enlarged cross-sectional view showing the bottom portion and the periphery of the projecting portion in a state where the pusher is fully pushed;
　以下、本発明の実施の形態を、添付図面を参照して説明する。 Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings.
　図１Ａは、本発明の一実施形態に係るシリンジ１の正面図であり、図１Ｂは、図１ＡのＩ－Ｉ線断面図である。シリンジ１は、針管１０と、針管１０が固定された外筒（バレル）２０と、外筒２０内に挿入された押し子（プランジャ）３０と、押し子の先端部に取り付けられたガスケット４０と、を備えている。 FIG. 1A is a front view of a syringe 1 according to one embodiment of the present invention, and FIG. 1B is a cross-sectional view taken along line II of FIG. 1A. The syringe 1 includes a needle tube 10, an outer cylinder (barrel) 20 to which the needle tube 10 is fixed, a plunger (plunger) 30 inserted into the outer cylinder 20, and a gasket 40 attached to the tip of the plunger. , is equipped with
　針管１０は、人体等に穿刺される部分である。針管１０は、例えばステンレス鋼等の適宜の金属から構成されており、先端部には針先を鋭利にするための刃面１１が形成されている。針管１０のサイズは、特に限定されるものではなく、例えばＩＳＯ９６２６に規定される１６～３３ゲージ（外径：１．７～０．２ｍｍ）のものを使用することができる。 The needle tube 10 is a part that is punctured into the human body or the like. The needle tube 10 is made of an appropriate metal such as stainless steel, and has a blade surface 11 formed at its distal end to sharpen the tip of the needle. The size of the needle tube 10 is not particularly limited, and for example, 16 to 33 gauge (outer diameter: 1.7 to 0.2 mm) defined by ISO9626 can be used.
　また、針管１０の針先の形状は、特に限定されるものではなく、ランセット加工やバックカット加工が施されたものであってもよい。また、針管１０は、内外径が軸方向において変化するものであってもよい。 Also, the shape of the needle tip of the needle tube 10 is not particularly limited, and may be one subjected to lancet processing or backcut processing. Further, the needle tube 10 may have inner and outer diameters that change in the axial direction.
　外筒２０は、人体に投与される薬液等を内部に収容する部分である。外筒２０は、例えばポリプロピレン、アクリロニトリル・ブタジエン・スチレン（ＡＢＳ）樹脂およびポリカーボネート等、透明または半透明の適宜の樹脂から構成されている。また、外筒２０は、薬液等を収容する内部空間を確定する有底円筒状の外筒本体部２１と、外筒本体部２１の先端部に突設された円筒状の突出部２２と、を有している。 The outer cylinder 20 is a part that internally accommodates a liquid medicine or the like to be administered to the human body. The outer cylinder 20 is made of an appropriate transparent or translucent resin such as polypropylene, acrylonitrile-butadiene-styrene (ABS) resin, polycarbonate, or the like. In addition, the outer cylinder 20 includes a bottomed cylindrical outer cylinder main body portion 21 that defines an internal space for accommodating a liquid medicine or the like, a cylindrical protruding portion 22 that protrudes from the distal end portion of the outer cylinder main body portion 21, have.
　外筒本体部２１は、内外径が略一定の円筒状の筒部２１ａと、筒部２１ａの先端側を閉塞する円盤状の底部２１ｂと、から構成されている。筒部２１ａの外周面２１ａ１後端部には、外周側に向けて突出する平面視で楕円形状のフランジ部２１ｃが設けられている。 The outer tube main body 21 is composed of a cylindrical tube 21a having a substantially constant inner and outer diameter, and a disk-shaped bottom 21b that closes the tip of the tube 21a. A rear end portion of the outer peripheral surface 21a1 of the cylindrical portion 21a is provided with an elliptical flange portion 21c protruding toward the outer peripheral side in plan view.
　フランジ部２１ｃは、シリンジ１の使用者が指（例えば、人差し指と中指）をかける部分であり、フランジ部２１ｃの先端側面２１ｃ１には、平面視でＣ字状に構成された滑り止めのための突起２１Ｃ２が設けられている。また、フランジ部２１ｃの正面側および背面側の端面には、シリンジ１を横向きの状態で机上等に安定的に載置するための平面部２１ｃ３がそれぞれ設けられている。 The flange portion 21c is a portion where the user of the syringe 1 puts fingers (for example, the index finger and the middle finger), and a tip side surface 21c1 of the flange portion 21c has a C-shaped non-slip surface in plan view. A protrusion 21C2 is provided. Flat portions 21c3 are provided on the front and rear end surfaces of the flange portion 21c so that the syringe 1 can be stably placed on a desk or the like in a horizontal state.
　筒部２１ａの外周面２１ａ１にはまた、収容した薬液等の量を表示する目盛り（図示省略）が設けられている。また、筒部２１ａの内周面２１ａ２の後端部には、周方向に連続する突起２１ｄが設けられている。この突起２１ｄは、押し子３０およびガスケット４０の外筒２０からの容易な脱落を防止するためのものである。 The outer peripheral surface 21a1 of the cylindrical portion 21a is also provided with a scale (not shown) that indicates the amount of the contained chemical solution. A rear end portion of the inner peripheral surface 21a2 of the tubular portion 21a is provided with a projection 21d continuous in the circumferential direction. This protrusion 21d is for preventing the plunger 30 and the gasket 40 from easily coming off from the outer cylinder 20. As shown in FIG.
　底部２１ｂの先端側面２１ｂ１の中央部には、突出部２２が先端側に向けて突設されている。また、突出部２２の周囲には、突出部２２を補強するための円筒状のカラー２３と、４つの台形板状のリブ２４が設けられている。 A projecting portion 22 protrudes toward the tip side from the central portion of the tip side surface 21b1 of the bottom portion 21b. A cylindrical collar 23 for reinforcing the protrusion 22 and four trapezoidal ribs 24 are provided around the protrusion 22 .
　カラー２３は、突出部２２の基端部の外周を囲むように設けられている。リブ２４は、突出部２２とカラー２３の間において周方向に均等な間隔で配置され、突出部２２、底部２１ｂおよびカラー２３と接続されている。また、リブ２４の外周側の端面２４ａには、針保護用のキャップ（図示省略）と係合する係合凹部２４ｂが設けられている。 The collar 23 is provided so as to surround the outer periphery of the proximal end of the projecting portion 22 . The ribs 24 are circumferentially evenly spaced between the protrusion 22 and the collar 23 and are connected to the protrusion 22 , the bottom 21 b and the collar 23 . Further, an engaging concave portion 24b is provided on an end face 24a on the outer peripheral side of the rib 24 so as to be engaged with a cap (not shown) for protecting the needle.
　本実施形態では、外筒２０における底部２１ｂおよび突出部２２の形状を工夫することで、シリンジ１の生産性を高めるようにしている。底部２１ｂおよび突出部２２の形状の詳細については、後述する。 In this embodiment, the productivity of the syringe 1 is improved by devising the shapes of the bottom portion 21b and the projecting portion 22 of the outer cylinder 20 . The details of the shapes of the bottom portion 21b and the projecting portion 22 will be described later.
　押し子３０は、外筒２０の後端側の開口から外筒２０内に挿入され、薬液等を投与する際に押圧操作されるものである。押し子３０は、横断面が十字状の棒状の部材であり、例えばポリスチレン、ポリプロピレンおよびポリカーボネート等の適宜の樹脂から構成されている。押し子３０の先端部には、ガスケット４０と係合する基端側が小径の段付き円柱状の係合部３１と、押圧操作時にガスケット４０と接触して押圧するフランジ状の押圧部３２と、が設けられている。また、押し子３０の後端部には、押圧操作時に使用者の指（例えば、親指）による押圧力を受ける円盤状の受力部３３が設けられている。 The pusher 30 is inserted into the outer cylinder 20 through an opening on the rear end side of the outer cylinder 20, and is pressed when administering a liquid medicine or the like. The pusher 30 is a rod-shaped member having a cross-shaped cross section, and is made of an appropriate resin such as polystyrene, polypropylene, polycarbonate, or the like. At the tip of the pusher 30, a stepped columnar engaging portion 31 with a small diameter on the base end side that engages with the gasket 40, a flange-like pressing portion 32 that contacts and presses the gasket 40 during pressing operation, is provided. A disk-shaped force receiving portion 33 is provided at the rear end portion of the pusher 30 to receive the pressing force of the user's finger (for example, thumb) during pressing operation.
　ガスケット４０は、外筒２０の後端側を密閉するものであり、例えば熱可塑性エラストマー、シリコーンゴムおよびブタジエンゴム等の適宜の弾性を有する材料から構成されている。図２Ａは、ガスケット４０の正面図であり、図２Ｂは、図２ＡのＩＩ－ＩＩ線断面図である。 The gasket 40 seals the rear end side of the outer cylinder 20, and is made of a material having suitable elasticity such as thermoplastic elastomer, silicone rubber and butadiene rubber. 2A is a front view of the gasket 40, and FIG. 2B is a cross-sectional view taken along line II-II of FIG. 2A.
　ガスケット４０は、後端側が開口した有底円筒状に構成されている。ガスケット４０の外周面４１は、軸方向の中間部４１ａがくびれた形状となっており、中間部４１ａよりも大径に構成された先端側摺動部４１ｂおよび後端側摺動部４１ｃが筒部２１ａの内周面２１ａ２と摺動するようになっている。 The gasket 40 is configured in a bottomed cylindrical shape with an open rear end side. The outer peripheral surface 41 of the gasket 40 has a shape in which an intermediate portion 41a in the axial direction is constricted. It slides on the inner peripheral surface 21a2 of the portion 21a.
　中間部４１ａの外径は、筒部２１ａの内径よりも小さく設定されている。また、先端側摺動部４１ｂおよび後端側摺動部４１ｃの外径は、筒部２１ａの内径よりも大きく設定されている。このように、先端側摺動部４１ｂおよび後端側摺動部４１ｃを設けることで、密閉性と摺動性を両立させることが可能となる。 The outer diameter of the intermediate portion 41a is set smaller than the inner diameter of the cylindrical portion 21a. Further, the outer diameters of the leading end side sliding portion 41b and the rear end side sliding portion 41c are set larger than the inner diameter of the cylindrical portion 21a. Thus, by providing the front end side sliding portion 41b and the rear end side sliding portion 41c, it is possible to achieve both sealing performance and slidability.
　なお、中間部４１ａの外径は、筒部２１ａの内径と略同一に設定されるものであってもよい。ガスケット４０は筒部２１ａから受ける圧縮力によって全体的に外径が縮小するため、この場合にも中間部４１ａと筒部２１ａの内周面２１ａ２が接触しないようにすることができる。また、先端側摺動部４１ｂおよび後端側摺動部４１ｃの外径は、互いに略同一に設定してもよいし、成形後の変形等を見越して異なる外径に設定してもよい。 The outer diameter of the intermediate portion 41a may be set substantially equal to the inner diameter of the cylindrical portion 21a. Since the outer diameter of the gasket 40 is reduced as a whole due to the compressive force received from the tubular portion 21a, the intermediate portion 41a and the inner peripheral surface 21a2 of the tubular portion 21a can be prevented from contacting each other in this case as well. In addition, the outer diameters of the front end side sliding portion 41b and the rear end side sliding portion 41c may be set substantially the same, or may be set to different outer diameters in anticipation of deformation after molding.
　ガスケット４０の先端面４２は、円錐台状に構成されており、中央部にはドーム状の凹部４２ａが設けられている。本実施形態では、先端面４２のテーパ角度を約１６０°に設定している。このように先端面４２のテーパ角度を大きく設定することで、先端面４２の突出量を低減し、筒部２１ａの外周面２１ａ１に設けられた目盛りの視認性を高めることが可能となる。 A tip surface 42 of the gasket 40 is configured in a truncated cone shape, and a dome-shaped concave portion 42a is provided in the central portion. In this embodiment, the taper angle of the tip surface 42 is set to about 160°. By setting the taper angle of the tip end face 42 large in this way, it is possible to reduce the protrusion amount of the tip end face 42 and improve the visibility of the scale provided on the outer peripheral face 21a1 of the cylindrical portion 21a.
　具体的には、薬液の投与量は、先端側摺動部４１ｂにおける内周面２１ａ２との接触面の先端位置に対応する目盛りを読むことで測定されるが、先端面４２の突出量が大きいと当該目盛りの近傍が暗くなって読み取りが困難となる場合がある。本実施形態では、先端面の突出量を低減することで、このような不具合を防止している。 Specifically, the dose of the liquid medicine is measured by reading the scale corresponding to the tip position of the contact surface with the inner peripheral surface 21a2 of the tip side sliding portion 41b, but the protrusion amount of the tip face 42 is large. and the vicinity of the scale becomes dark, making it difficult to read. In this embodiment, such a problem is prevented by reducing the protrusion amount of the tip surface.
　ガスケット４０の内周面４３は、押し子３０の係合部３１と係合するよう後端側の内径が先端側よりも小径に構成されている。また、内周面４３の後端部には、係合部３１の挿入を容易にすべく、後端側に向けて漸次拡径するテーパ状の導入部４３ａが設けられている。また、ガスケット４０の後端面４４は、軸心と略直交する平面状に構成され、押し子３０の押圧部３２と安定的に接触して押圧されるようになっている。 The inner peripheral surface 43 of the gasket 40 is configured such that the inner diameter on the rear end side is smaller than that on the front end side so as to engage with the engaging portion 31 of the pusher 30 . A tapered introduction portion 43a is provided at the rear end portion of the inner peripheral surface 43 so that the engagement portion 31 can be easily inserted. Further, the rear end surface 44 of the gasket 40 is formed in a planar shape substantially orthogonal to the axis, and is stably brought into contact with and pressed by the pressing portion 32 of the pusher 30 .
　図３は、図１ＡのＩ－Ｉ線断面図であり、底部２１ｂおよび突出部２２の周辺を拡大して示した図である。突出部２２は、基端部に後端側に向けて外径が漸次拡径するテーパ状の拡径部２２ａを有しており、この拡径部２２ａが底部２１ｂの先端側面２１ｂ１と接続されている。 FIG. 3 is a cross-sectional view taken along the line II of FIG. 1A, showing an enlarged view of the periphery of the bottom portion 21b and the protruding portion 22. FIG. The projecting portion 22 has a tapered enlarged diameter portion 22a at the base end portion, the outer diameter of which gradually increases toward the rear end side. ing.
　突出部２２の内部には、針管１０の後端側が挿入されて固定される孔である針管挿入部２５が設けられている。針管挿入部２５は、突出部２２の先端面２２ｂから軸方向に沿って穿たれており、後端側の針管支持部２５ａおよび先端側の接着剤収容部２５ｂから構成されている。 A needle tube insertion portion 25, which is a hole into which the rear end side of the needle tube 10 is inserted and fixed, is provided inside the protruding portion 22. The needle tube insertion portion 25 is axially bored from the distal end surface 22b of the projecting portion 22, and is composed of a needle tube support portion 25a on the rear end side and an adhesive agent accommodating portion 25b on the distal end side.
　針管支持部２５ａは、内周面２５ａ１が針管１０の外径よりもやや大きい内径で軸方向に略一定の内径に構成されると共に、段差状の後端面２５ａ２を有している。すなわち、針管支持部２５ａは、内周面２５ａ１によって針管１０を外筒２０の軸心に沿う姿勢に保持すると共に、後端面２５ａ２を針管１０の後端面１２と当接させることによって針管１０を軸方向において位置決めするように構成されている。 The needle tube support portion 25a has an inner peripheral surface 25a1 that is slightly larger than the outer diameter of the needle tube 10 and has a substantially constant inner diameter in the axial direction, and has a stepped rear end surface 25a2. That is, the needle tube support portion 25a holds the needle tube 10 in a posture along the axial center of the outer cylinder 20 by means of the inner peripheral surface 25a1, and brings the needle tube 10 to the axis by bringing the rear end surface 25a2 into contact with the rear end surface 12 of the needle tube 10. It is configured for positioning in a direction.
　接着剤収容部２５ｂは、針管支持部２５ａから先端側に向けて漸次内径が拡大するテーパ状に構成されており、針管１０との間に接着剤５０が充填される充填空間を形成している。本実施形態では、接着剤収容部２５ｂに周方向に連続する２つの溝２５ｂ１を設け、硬化後の接着剤５０が溝２５ｂ１と係合するようにしている。このようにすることで、外筒２０を構成する樹脂の接着性が悪い場合にも、針管１０の外筒２０からの脱落を防止することが可能となる。なお、接着剤収容部２５ｂに適宜の表面処理を施す等して、接着性を高めるようにしてもよいことは言うまでもない。 The adhesive containing portion 25b is tapered such that the inner diameter gradually increases from the needle tube supporting portion 25a toward the distal end side, and forms a filling space in which the adhesive 50 is filled between the needle tube 10 and the adhesive accommodating portion 25b. . In this embodiment, two circumferentially continuous grooves 25b1 are provided in the adhesive containing portion 25b so that the cured adhesive 50 engages with the grooves 25b1. By doing so, it is possible to prevent the needle tube 10 from falling off from the outer cylinder 20 even when the adhesiveness of the resin forming the outer cylinder 20 is poor. Needless to say, the adhesive containing portion 25b may be subjected to appropriate surface treatment or the like to enhance the adhesiveness.
　突出部２２および底部２１ｂの内部には、針管挿入部２５と外筒本体部２１の内部空間を連通する流通路２６が設けられている。この流通路２６は、薬液等が流通する通路であり、針管挿入部２５に繋がる先端側の小径部２６ａと、外筒本体部２１の内部空間と小径部２６ａを繋ぐ大径部２６ｂと、から構成されている。 A flow passage 26 that communicates the inner space of the needle tube insertion portion 25 and the outer cylinder main body portion 21 is provided inside the projecting portion 22 and the bottom portion 21b. The flow passage 26 is a passage through which a liquid medicine or the like flows, and is composed of a small diameter portion 26a on the distal end side connected to the needle tube insertion portion 25 and a large diameter portion 26b connecting the inner space of the outer cylinder main body portion 21 and the small diameter portion 26a. It is configured.
　小径部２６ａは、針管１０外径よりも小さく針管１０の内径よりも大きい内径で軸方向に略一定の内径に設定されている。本実施形態では、小径部２６ａを設けることで、針管支持部２５ａに後端面２５ａ２を形成し、針管１０を軸方向に位置決めすることを可能としている。 The small-diameter portion 26a has an inner diameter that is smaller than the outer diameter of the needle tube 10 and larger than the inner diameter of the needle tube 10, and is set to have a substantially constant inner diameter in the axial direction. In this embodiment, by providing the small-diameter portion 26a, the needle tube support portion 25a is formed with a rear end surface 25a2, and the needle tube 10 can be positioned in the axial direction.
　大径部２６ｂは、全体的に小径部２６ａよりも大きい内径に構成されており、段差状の先端面２６ｂ１を有している。大径部２６ｂはさらに、先端面２６ｂ１から後端側に向けて漸次拡径すると共に、後端側に向けて拡径率が漸次減少する第１丸み部２６ｂ２と、第１丸み部２６ｂ２から後端側に向けて僅かに漸次拡径するテーパ部２６ｂ３と、テーパ部２６ｂ３から後端側に向けて漸次拡径すると共に、後端側に向けて拡径率が漸次増大する第２丸み部２６ｂ４と、を有して構成されている。 The large-diameter portion 26b has an inner diameter larger than that of the small-diameter portion 26a as a whole, and has a stepped tip surface 26b1. The large-diameter portion 26b further includes a first rounded portion 26b2 whose diameter gradually increases toward the rear end side from the front end surface 26b1, and whose diameter expansion rate gradually decreases toward the rear end side, and a first rounded portion 26b2. A tapered portion 26b3 that gradually expands in diameter toward the end side, and a second rounded portion 26b4 that gradually expands in diameter from the tapered portion 26b3 toward the rear end side and whose diameter expansion rate gradually increases toward the rear end side. and
　大径部２６ｂは、薬液等が流通する通路としてだけではなく、外筒２０の樹脂成形時に針管支持部２５ａおよび小径部２６ａならびにその近傍に生じるヒケやボイド等の成形不良を防止するための肉盗みとして機能するように構成されている。 The large-diameter portion 26b serves not only as a passage for liquid medicine, etc., but also to prevent molding defects such as sink marks and voids that occur in the needle tube support portion 25a, the small-diameter portion 26a, and their vicinity during resin molding of the outer cylinder 20. Configured to work as a steal.
　針管支持部２５ａおよび小径部２６ａは、樹脂成形の金型のコアピンによって成形される部分であり、突出部２２の先端側および底部２１ｂの外周側よりも放熱性が悪い領域となっている。従って、針管支持部２５ａおよび小径部２６ａ周辺では、金型内に樹脂を充填した後の冷却工程において、先に温度が低下した突出部２２の先端側および底部２１ｂの外周側の樹脂から引っ張られることでヒケやボイド等が発生しやすく、針管支持部２５ａおよび小径部２６ａが適切な寸法形状に成形されない可能性がある。 The needle tube support portion 25a and the small-diameter portion 26a are portions formed by a core pin of a resin mold, and are regions with poorer heat dissipation than the tip side of the projecting portion 22 and the outer peripheral side of the bottom portion 21b. Therefore, around the needle tube support portion 25a and the small-diameter portion 26a, in the cooling step after filling the resin in the mold, the resin on the front end side of the protruding portion 22 and the outer peripheral side of the bottom portion 21b whose temperature has decreased earlier is pulled. As a result, sink marks, voids, and the like are likely to occur, and there is a possibility that the needle tube support portion 25a and the small-diameter portion 26a will not be formed into appropriate dimensions and shapes.
　本実施形態では、大径部２６ｂの先端面２６ｂ１（換言すれば、小径部２６ａの後端）が底部２１ｂの先端側面２１ｂ１よりも先端側に位置するように小径部２６ａおよび大径部２６ｂを設けることで、針管支持部２５ａおよび小径部２６ａ近傍の肉厚を十分に低減し、その周辺の冷却速度を向上させると共に、底部２１ｂの外周側の先に温度が低下した樹脂による引っ張りの影響が針管支持部２５ａおよび小径部２６ａに及ぶのを抑制することを可能としている。すなわち、針管支持部２５ａおよび小径部２６ａにおけるヒケやボイド等の成形不良の発生を効果的に防止することを可能としている。 In the present embodiment, the small-diameter portion 26a and the large-diameter portion 26b are arranged so that the front end surface 26b1 of the large-diameter portion 26b (in other words, the rear end of the small-diameter portion 26a) is located on the front end side of the front end side surface 21b1 of the bottom portion 21b. By providing, the thickness of the vicinity of the needle tube support portion 25a and the small diameter portion 26a is sufficiently reduced, the cooling rate of the surroundings is improved, and the effect of the tension due to the resin whose temperature has decreased is reduced at the outer peripheral side of the bottom portion 21b. It is possible to suppress the needle tube supporting portion 25a and the small diameter portion 26a. That is, it is possible to effectively prevent the occurrence of molding defects such as sink marks and voids in the needle tube support portion 25a and the small diameter portion 26a.
　これにより、針管支持部２５ａおよび小径部２６ａが適切な寸法形状に成形されるため、針管を適切に位置決めして外筒に固定することが可能となる。すなわち、本実施形態のシリンジ１は、良好な組み立て性および高い歩留りを兼ね備え、生産性に優れたものとなっている。 As a result, the needle tube support portion 25a and the small diameter portion 26a are formed to have appropriate dimensions and shapes, so that the needle tube can be appropriately positioned and fixed to the outer cylinder. That is, the syringe 1 of the present embodiment has both good assembling property and high yield, and is excellent in productivity.
　特に本実施形態では、小径部２６ａと大径部２６ｂの間に段差を設けると共に、大径部２６ｂに後端側に向けて拡径率が漸次減少する部分を設けることで、小径部２６ａの近傍を大きく肉抜きし、より効果的に成形不良を防止することを可能としている。さらに、拡径部２２ａおよび第２丸み部２６ｂ４を、互いに対応させて設けることで、突出部２２と底部２１ｂの接続領域における肉厚変化を低減することによっても、より効果的に成形不良を防止することを可能としている。 In particular, in this embodiment, a step is provided between the small diameter portion 26a and the large diameter portion 26b, and a portion in which the diameter expansion rate gradually decreases toward the rear end side is provided in the large diameter portion 26b. It is possible to prevent molding defects more effectively by largely hollowing out the vicinity. Furthermore, by providing the enlarged diameter portion 22a and the second rounded portion 26b4 in correspondence with each other, it is possible to reduce the change in thickness in the connecting region between the projecting portion 22 and the bottom portion 21b, thereby more effectively preventing defective molding. making it possible to
　底部２１ｂの先端側面２１ｂ１は、外筒２０の軸心と略直交する平面状に構成されている。一方、外筒本体部２１の内部空間に面する底部２１ｂの後端側面２１ｂ２は、外周側から軸心側（大径部２６ｂ側）に向けて軸方向の漸次厚みが減少するテーパ状に構成されている。本実施形態では、底部２１ｂをこのように構成することで、突出部２２と底部２１ｂの接続領域における肉厚を低減し、より一層効果的に成形不良を防止することを可能としている。 A tip side surface 21b1 of the bottom portion 21b is formed in a planar shape substantially orthogonal to the axial center of the outer cylinder 20. As shown in FIG. On the other hand, the rear end side surface 21b2 of the bottom portion 21b facing the inner space of the outer cylinder main body portion 21 is tapered such that the thickness in the axial direction gradually decreases from the outer peripheral side toward the axial center side (large diameter portion 26b side). It is In the present embodiment, by configuring the bottom portion 21b in this manner, the thickness of the connecting region between the protruding portion 22 and the bottom portion 21b can be reduced, making it possible to prevent molding defects more effectively.
　さらに、本実施形態では、底部２１ｂの後端側面２１ｂ２を、大径部２６ｂに繋がる第１テーパ面２１ｂ２ａと、第１テーパ面２１ｂ２ａよりも外周側の第２テーパ面２１ｂ２ｂと、の２種類のテーパ状の面から構成すると共に、第１テーパ面２１ｂ２ａのテーパ角度を第２テーパ面２１ｂ２ｂのテーパ角度よりも大きく設定することで、ガスケット４０の先端面４２との密着性を高めデッドスペースを低減するようにしている。 Furthermore, in the present embodiment, the rear end side surface 21b2 of the bottom portion 21b is divided into two types: a first tapered surface 21b2a connected to the large diameter portion 26b and a second tapered surface 21b2b on the outer peripheral side of the first tapered surface 21b2a. The tapered surface and the taper angle of the first tapered surface 21b2a are set larger than the taper angle of the second tapered surface 21b2b to increase the adhesion between the gasket 40 and the tip surface 42 and reduce the dead space. I am trying to
　図４は、図１ＡのＩ－Ｉ線断面図であり、押し子３０を押し切った状態での底部２１ｂおよび突出部２２の周辺を拡大して示した図である。押し子３０を押し切った状態では、ガスケット４０の先端面４２は、底部２１ｂの後端側面２１ｂ２と適切に密着した状態となる。 FIG. 4 is a cross-sectional view taken along the line II of FIG. 1A, showing an enlarged view of the periphery of the bottom portion 21b and the protruding portion 22 when the pusher 30 is fully pushed. When the plunger 30 is fully pushed, the front end surface 42 of the gasket 40 is in a state of being in proper contact with the rear end side surface 21b2 of the bottom portion 21b.
　本実施形態では、ガスケット４０の先端面４２の約１６０°のテーパ角度に対し、第１テーパ面２１ｂ２ａのテーパ角度を約１７４°に設定し、第２テーパ面２１ｂ２ｂのテーパ角度を約１４５°に設定することで、ガスケット４０の先端面４２は、底部２１ｂの後端側面２１ｂ２と適切に密着させ、両者に間に残液が生じないようにしている。 In this embodiment, the taper angle of the first tapered surface 21b2a is set to about 174°, and the taper angle of the second tapered surface 21b2b is set to about 145° with respect to the taper angle of the tip surface 42 of the gasket 40 of about 160°. By setting, the tip end face 42 of the gasket 40 is brought into close contact with the rear end side face 21b2 of the bottom portion 21b so that residual liquid does not occur between them.
　本実施形態ではまた、テーパ角度の大きい（軸心と直交する平面に近い）第１テーパ面２１ｂ２ａを設けることで、ガスケット４０の先端面４２の凹部４２ａの周縁部を大径部２６ｂ内に入り込ませ、外筒２０内のデッドスペースをさらに削減するようにしている。また、大径部２６ｂに第２丸み部２６ｂ４を設けると共に、ガスケット４０の先端面４２に凹部４２ａを設けることで、ガスケット４０の先端面４２が大径部２６ｂ内に入りやすいようにしている。 In the present embodiment, by providing the first tapered surface 21b2a with a large taper angle (close to a plane orthogonal to the axis), the peripheral edge of the recess 42a of the tip surface 42 of the gasket 40 is inserted into the large diameter portion 26b. The dead space in the outer cylinder 20 is further reduced. Further, by providing the second rounded portion 26b4 in the large diameter portion 26b and providing the recess 42a in the tip surface 42 of the gasket 40, the tip surface 42 of the gasket 40 can easily enter the large diameter portion 26b.
　また、本実施形態では、底部２１ｂの後端側面２１ｂ２および大径部２６ｂに、後端側に向けて突出する部分や逆向きのテーパ状に構成される部分を設けていないため、薬液等を吸引する際に生じた気泡をスムーズに小径部２６ａに向けて誘導し、針管１０の先端から排出することが可能となっている。 In addition, in the present embodiment, the rear end side surface 21b2 and the large diameter portion 26b of the bottom portion 21b are not provided with a portion projecting toward the rear end side or a portion configured in a tapered shape in the opposite direction. It is possible to smoothly guide air bubbles generated during suction toward the small-diameter portion 26 a and discharge them from the tip of the needle tube 10 .
　なお、針管挿入部２５および流通路２６の横断面の形状は、円形状に限定されず、例えば楕円形状や多角形状等、種々の形状を採用することができる。この場合、小径部２６ａは、軸心と直交するいずれかの方向において針管１０の外径よりも幅狭に構成されるものであればよい。また、大径部２６ｂは、軸心と直交するいずれかの方向において小径部２６ａの内径よりも幅広に構成されるものであればよく、軸心と直交するいずれかの方向において拡幅率が減少する部分を有することが好ましい。 The cross-sectional shapes of the needle tube insertion portion 25 and the flow path 26 are not limited to circular shapes, and various shapes such as elliptical shapes and polygonal shapes can be adopted. In this case, the small-diameter portion 26a may be configured to be narrower than the outer diameter of the needle tube 10 in any direction perpendicular to the axis. In addition, the large diameter portion 26b may be wider than the inner diameter of the small diameter portion 26a in any direction perpendicular to the axis, and the width expansion ratio is reduced in any direction perpendicular to the axis. It is preferable to have a portion that
　また、大径部２６ｂの先端面２６ｂ１は、テーパ状に構成されるものであってもよいし、先端面２６ｂ１を省略して第１丸み部２６ｂ２を小径部２６ａに繋げるようにしてもよい。また、底部２１ｂの後端側面２１ｂ２は、１つのテーパ面から構成されるものであってもよいし、曲面から構成されるものであってもよい。また、底部２１ｂの先端側面２１ｂ１をテーパ状に構成するようにしてもよい。 Also, the tip surface 26b1 of the large diameter portion 26b may be tapered, or the tip surface 26b1 may be omitted and the first rounded portion 26b2 may be connected to the small diameter portion 26a. Further, the rear end side surface 21b2 of the bottom portion 21b may be composed of one tapered surface, or may be composed of a curved surface. Further, the tip side surface 21b1 of the bottom portion 21b may be tapered.
　また、針管挿入部２５から接着剤収容部２５ｂを省略し、溶着またはインサート成形によって針管１０を外筒２０に固定するようにしてもよい。 Alternatively, the adhesive containing portion 25b may be omitted from the needle tube insertion portion 25, and the needle tube 10 may be fixed to the outer cylinder 20 by welding or insert molding.
　以上、本発明の実施の形態について説明したが、本発明のシリンジおよびシリンジ用外筒は、上述した実施の形態に限定されるものではなく、本発明の要旨を逸脱しない範囲内において種々変更を加え得ることは勿論である。例えば、シリンジ１の各部の形状および配置は、上述の実施形態において示した形状および配置に限定されるものではなく、既知の種々の形状および配置を採用することができる。 Although the embodiments of the present invention have been described above, the syringe and syringe outer cylinder of the present invention are not limited to the above-described embodiments, and various modifications can be made without departing from the gist of the present invention. It is of course possible to add For example, the shape and arrangement of each part of the syringe 1 are not limited to the shapes and arrangements shown in the above-described embodiments, and various known shapes and arrangements can be adopted.
　また、上述の実施形態において示した作用および効果は、本発明から生じる最も好適な作用および効果を列挙したものに過ぎず、本発明による作用および効果は、これらに限定されるものではない。 In addition, the actions and effects shown in the above-described embodiments are merely enumerations of the most suitable actions and effects resulting from the present invention, and the actions and effects of the present invention are not limited to these.
　１　シリンジ
　１０　針管
　２０　外筒
　２１　外筒本体部
　２１ａ　筒部
　２１ｂ　底部
　２１ｂ１　底部の先端側面
　２１ｂ２　底部の後端側面
　２１ｂ２ａ　第１テーパ面
　２１ｂ２ｂ　第２テーパ面
　２２　突出部
　２５　針管挿入部
　２６　流通路
　２６ａ　小径部
　２６ｂ　大径部
  1 syringe 10 needle tube 20 outer cylinder 21 outer cylinder main body 21a cylindrical part 21b bottom 21b1 tip side surface of the bottom part 21b2 rear end side surface of the bottom part 21b2a first tapered surface 21b2b second tapered surface 22 protruding part 25 needle insertion part 26 flow path 26a small diameter Part 26b large diameter part

Claims (6)

  1. 　針管および前記針管が固定される外筒を備え、
    　前記外筒は、
    　底部および筒部からなる有底筒状の外筒本体部と、
    　前記底部に突設され、前記針管が固定される突出部と、
    　前記突出部に設けられ、前記針管が挿入される針管挿入部と、
    　前記外筒本体部の内部空間と前記針管挿入部を連通する流通路と、を有し、
    　前記流通路は、
    　前記針管挿入部に繋がる位置に設けられ、前記針管の外径よりも小径または幅狭の小径部と、
    　前記外筒本体部の内部空間と前記小径部を繋ぐように設けられ、前記小径部よりも大径または幅広の大径部と、を有し、
    　前記小径部は、前記底部の先端側面よりも先端側に設けられることを特徴とするシリンジ。     A needle tube and an outer cylinder to which the needle tube is fixed are provided,
    The outer cylinder is
    a bottomed cylindrical outer cylinder main body consisting of a bottom and a cylinder;
    a projecting portion projecting from the bottom portion and to which the needle tube is fixed;
    a needle tube insertion portion provided in the projecting portion and into which the needle tube is inserted;
    a flow path communicating between the inner space of the outer cylinder main body and the needle tube insertion portion;
    The flow passage is
    A small-diameter portion provided at a position connected to the needle tube insertion portion and having a smaller diameter or narrower width than the outer diameter of the needle tube;
    a large-diameter portion provided to connect the inner space of the outer cylinder main body and the small-diameter portion and having a larger diameter or a wider width than the small-diameter portion;
    The syringe, wherein the small diameter portion is provided closer to the tip side than the tip side surface of the bottom portion.
  2. 　請求項１に記載のシリンジにおいて、
    　前記大径部は、前記小径部との間に段差を形成するように構成されることを特徴とするシリンジ。     A syringe according to claim 1,
    The syringe, wherein the large-diameter portion is configured to form a step with the small-diameter portion.
  3. 　請求項１または２に記載のシリンジにおいて、
    　前記大径部は、後端側に向けて拡径率または拡幅率が減少する部分を有することを特徴とするシリンジ。     The syringe according to claim 1 or 2,
    The syringe, wherein the large-diameter portion has a portion in which the diameter expansion ratio or the width expansion ratio decreases toward the rear end side.
  4. 　請求項１から３までのいずれか１項に記載のシリンジにおいて、
    　前記底部は、前記大径部側に向けて厚みが漸次減少するように構成されることを特徴とするシリンジ。     In the syringe according to any one of claims 1 to 3,
    The syringe, wherein the bottom portion is configured such that the thickness thereof gradually decreases toward the large-diameter portion.
  5. 　請求項４に記載のシリンジにおいて、
    　前記底部は、前記大径部に繋がる第１テーパ面、および前記第１テーパ面よりも外周側の第２テーパ面を後端側面に有し、
    　前記第１テーパ面のテーパ角度は、前記第２テーパ面のテーパ角度よりも大きいことを特徴とするシリンジ。     A syringe according to claim 4,
    The bottom portion has a first tapered surface connected to the large diameter portion and a second tapered surface on the outer peripheral side of the first tapered surface on the rear end side surface,
    A syringe, wherein the taper angle of the first tapered surface is larger than the taper angle of the second tapered surface.
  6. 　底部および筒部からなる有底筒状の外筒本体部と、
    　前記底部に突設され、針管が固定される突出部と、
    　前記突出部に設けられ、前記針管が挿入される針管挿入部と、
    　前記外筒本体部の内部空間と前記針管挿入部を連通する流通路と、を備え、
    　前記流通路は、
    　前記針管挿入部に繋がる位置に設けられ、前記針管の外径よりも小径または幅狭の小径部と、
    　前記外筒本体部の内部空間と前記小径部を繋ぐように設けられ、前記小径部よりも大径または幅広の大径部と、を有し、
    　前記小径部は、前記底部の先端側面よりも先端側に設けられることを特徴とするシリンジ用外筒。
          a bottomed cylindrical outer cylinder main body consisting of a bottom and a cylinder;
    a projecting portion projecting from the bottom portion and to which a needle tube is fixed;
    a needle tube insertion portion provided in the projecting portion and into which the needle tube is inserted;
    a flow passage that communicates between the inner space of the outer cylinder main body and the needle tube insertion portion,
    The flow passage is
    A small-diameter portion provided at a position connected to the needle tube insertion portion and having a smaller diameter or narrower width than the outer diameter of the needle tube;
    a large-diameter portion provided to connect the inner space of the outer cylinder main body and the small-diameter portion and having a larger diameter or a wider width than the small-diameter portion;
    The syringe outer cylinder, wherein the small-diameter portion is provided closer to the tip side than the tip side surface of the bottom portion.
PCT/JP2022/001744 2021-02-12 2022-01-19 Syringe and syringe barrel WO2022172708A1 (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008513063A (en) * 2004-09-16 2008-05-01 インビロ メディカル デバイシーズ リミテッド Disposable safety syringe to prevent needle stick injury and reuse
JP2012254102A (en) * 2011-06-07 2012-12-27 Taisei Kako Co Ltd Needle-mounted barrel and prefilled syringe
JP1492696S (en) * 2013-08-27 2014-03-17
JP2014083292A (en) * 2012-10-25 2014-05-12 Taisei Kako Co Ltd Syringe
US20140316336A1 (en) * 2011-01-11 2014-10-23 Abu Dhabi National Industrial Projects Co. Auto-disable safety syringe

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008513063A (en) * 2004-09-16 2008-05-01 インビロ メディカル デバイシーズ リミテッド Disposable safety syringe to prevent needle stick injury and reuse
US20140316336A1 (en) * 2011-01-11 2014-10-23 Abu Dhabi National Industrial Projects Co. Auto-disable safety syringe
JP2012254102A (en) * 2011-06-07 2012-12-27 Taisei Kako Co Ltd Needle-mounted barrel and prefilled syringe
JP2014083292A (en) * 2012-10-25 2014-05-12 Taisei Kako Co Ltd Syringe
JP1492696S (en) * 2013-08-27 2014-03-17

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