WO2022150947A1 - Structural composition of wound dressing - Google Patents
Structural composition of wound dressing Download PDFInfo
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- WO2022150947A1 WO2022150947A1 PCT/CN2021/071191 CN2021071191W WO2022150947A1 WO 2022150947 A1 WO2022150947 A1 WO 2022150947A1 CN 2021071191 W CN2021071191 W CN 2021071191W WO 2022150947 A1 WO2022150947 A1 WO 2022150947A1
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- Prior art keywords
- wound
- wound dressing
- nano
- base material
- gold
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 9
- 239000000463 material Substances 0.000 claims abstract description 27
- 239000010931 gold Substances 0.000 claims abstract description 23
- 229910052737 gold Inorganic materials 0.000 claims abstract description 23
- 238000004544 sputter deposition Methods 0.000 claims abstract description 19
- 229920000742 Cotton Polymers 0.000 claims abstract description 13
- 239000000758 substrate Substances 0.000 claims abstract description 13
- 239000004744 fabric Substances 0.000 claims abstract description 5
- 239000000835 fiber Substances 0.000 claims abstract description 5
- 229910052751 metal Inorganic materials 0.000 claims description 12
- 239000002184 metal Substances 0.000 claims description 12
- 239000012530 fluid Substances 0.000 claims description 6
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 3
- 229910052802 copper Inorganic materials 0.000 claims description 3
- 239000010949 copper Substances 0.000 claims description 3
- 229910052709 silver Inorganic materials 0.000 claims description 3
- 239000004332 silver Substances 0.000 claims description 3
- 229910052719 titanium Inorganic materials 0.000 claims description 3
- 239000010936 titanium Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 6
- WSNMPAVSZJSIMT-UHFFFAOYSA-N COc1c(C)c2COC(=O)c2c(O)c1CC(O)C1(C)CCC(=O)O1 Chemical compound COc1c(C)c2COC(=O)c2c(O)c1CC(O)C1(C)CCC(=O)O1 WSNMPAVSZJSIMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 description 35
- 208000027418 Wounds and injury Diseases 0.000 description 35
- 230000000694 effects Effects 0.000 description 12
- 230000000844 anti-bacterial effect Effects 0.000 description 8
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 8
- 230000029663 wound healing Effects 0.000 description 7
- 210000004204 blood vessel Anatomy 0.000 description 6
- 230000035755 proliferation Effects 0.000 description 5
- 238000011084 recovery Methods 0.000 description 5
- 230000003213 activating effect Effects 0.000 description 4
- 230000020411 cell activation Effects 0.000 description 4
- 230000000840 anti-viral effect Effects 0.000 description 3
- 239000002131 composite material Substances 0.000 description 3
- 230000004913 activation Effects 0.000 description 2
- 230000004663 cell proliferation Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- 239000002105 nanoparticle Substances 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 239000003574 free electron Substances 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive plasters or dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
Definitions
- the structural composition of a wound dressing refers to the technical field of a composite cell activation and proliferation material to form a skin-friendly dressing to help blood vessel proliferation, accelerate wound healing, and not stick to wounds.
- the existing wound treatment usually involves cleaning and sterilizing the wound first, then applying ointment, wrapping it with gauze or similar materials, and waiting for the wound to heal by itself, and then removing the gauze and other external covering and fixing materials.
- This method is not a big problem for ordinary small wounds, but for large wounds or wounded patients who are difficult to heal due to physical problems (such as diabetic patients), the recovery time of the wound is long, and the dressing needs to be changed many times, which is very laborious.
- the dressing is changed and the gauze is removed, the wrapping such as the gauze is often combined with the tissue fluid of the wound, causing the wound to be pulled and torn again, causing the wound to be damaged again and taking longer to heal.
- a more advanced method is to use artificial skin covering, but its improvement effect is still extremely limited, and it does not help wound healing.
- a wound dressing structure of the present invention especially a composite cell activation and proliferation material with antibacterial and antiviral effects, mainly includes a combination of three-layer structures, wherein the first structure is a base material, which is composed of three layers.
- a non-stick base material including but not limited to fibers, yarns and fabrics
- the second structure is a nano-gold sputtering layer, which is combined with one side of the base material
- the third structure is a blood-sucking cotton sheet, combined with the other side of the substrate.
- the use method of the present invention is to use the nano-gold sputtering layer to face the wound, through the effect of activating cells of the nano-gold to help the blood vessels to proliferate, which can help the recovery of the wound, and the intermediate base material, through its non-stick properties, cooperates with another
- the combination of the side blood-sucking cotton pads can smoothly absorb tissue fluid on the cotton pads, prevent the wound from sticking, and facilitate the separation of the dressing material from the wound to achieve the effect of benefiting wound healing.
- the substrate is a basic material including but not limited to fibers, yarns and fabrics.
- the base material is a material structure that does not cause adhesion to the wound tissue fluid, including but not limited to a mesh structure.
- a multi-metal nano sputtering layer is combined between the base material and the blood-sucking cotton sheet.
- the metals of the multi-metal nano sputtering layer include but are not limited to silver, copper, and titanium.
- Fig. 1 is the cross-sectional schematic diagram of the material combination structure of the present invention
- FIG. 2 is a schematic diagram of an application embodiment of the present invention.
- the present invention is a wound dressing structure 1, which mainly includes a three-layer structure, wherein the first structure is a substrate 11, which is made of a kind of material including but not limited to fibers, yarns and fabrics.
- the basic material formed especially the use including but not limited to the mesh structure, and the material that does not cause adhesion with the wound tissue fluid
- the second structure is the nano-gold sputtering layer 12, and the nano-gold is bonded to the substrate 11 by sputtering. It is formed from one side of the base material
- the third structure is a blood-sucking cotton sheet 13, which is combined with the other side 11 of the base material.
- the wound dressing structure composition 1 of the present invention is that the nano-gold sputtering layer 12 faces the wound, and the nano-gold has the effect of activating cells to help the proliferation of blood vessels, which can help the recovery of the wound, and the intermediate substrate 11 passes through it.
- the non-stick properties, combined with the combination of the other side of the blood-sucking cotton sheet 13, can smoothly absorb the tissue fluid exuded from the wound into the blood-sucking cotton sheet 13, which can prevent the wound from sticking to the substrate 11, and can facilitate the structure of the wound dressing.
- Composition 1 is separated from the wound as a whole to achieve the effect of benefiting wound healing.
- a feature of the present invention is to use nano-gold to accelerate wound treatment, and gold has the effect of activating cells and assisting blood vessel proliferation, which has been confirmed in many studies.
- the known application fields are limited to the use of metal-bonded bulk gold or thin-film gold structures. Although they can produce a certain cell activation effect, they are still limited.
- the nano-gold sputtering layer 12 structure in the present invention There are considerable differences in the activation effect of the gold nanoparticles. The main reason is that free electrons can move freely in bulk gold or thin film gold, but they will be greatly restricted when they are on the surface of gold nanoparticles. In the case of free movement, it is easier to release, and the released electrons are more effective for the activation of external cells and blood vessels.
- the nano-gold sputtering layer 12 has the unique effect of antibacterial effect but does not harm cells, and is very suitable for use in human wounds, which need to prevent bacterial infection, as well as assist vascular proliferation and cell activation applications.
- a multi-metal nano-sputtering layer 2 can be combined between the substrate 11 and the blood-sucking cotton sheet 13, which includes but is not limited to a composite type of nano-metal such as silver, copper, and titanium.
- the sputtered layer line structure, the multi-metal nano-sputtered layer 2 can use the redox potential difference between different metals to form an electron sea on its surface, and then become an electronic shield, providing antibacterial and antiviral effects on the outside, the detailed technical content can be found in The same PCT application No. PCT/CN2020/129986 filed by the applicant on December 19, 2020, can increase the inner layer nano-gold sputtering layer 12 composed of the wound dressing structure 1 of the present invention to accelerate the treatment of wounds, isolate external bacteria and viruses. effect.
- the structure of the antibacterial, antiviral, and easy-to-peel wound dressing that accelerates wound healing completed by the present invention is composed of 1. It is the first method to use nano-gold, which has both the proper antibacterial and rapid wound-healing functions, and the unique surface electrons of nano-gold.
- the release activity can provide the best physical function for wound recovery, and with the easy-to-peel substrate, as well as the physical antibacterial mechanism of the outer layer of blood-sucking cotton sheet and multi-metal nano-sputtering layer, it can be used without involving any chemicals. , to achieve perfect antibacterial and accelerated wound healing, and at the same time, it has the characteristics of easy peeling, and obtains better industrial utilization value.
Abstract
Structural composition (1) of a wound dressing, mainly comprising three layers of structures; a structure I is a substrate (11) and is a non-adhesive foundational material made of, but not limited to, fibers, yarns and fabrics; a structure II is a nano-gold sputtering layer (12) and is bonded to one side of the substrate (11); a structure III is a blood absorbing cotton pad (13) and is bonded to the other side of the substrate (11); a use method of the structural composition comprises making the nano-gold sputtering layer (12) face a wound.
Description
一种伤口敷料的结构组成,尤其指一种复合细胞活化增生材料组成亲肤性敷料,以帮助血管增生,加速伤口愈合,及不沾黏伤口的技术领域。The structural composition of a wound dressing, in particular, refers to the technical field of a composite cell activation and proliferation material to form a skin-friendly dressing to help blood vessel proliferation, accelerate wound healing, and not stick to wounds.
现有对于伤口的处理,通常都是先清洁和消毒伤口之后,涂抹药膏,以纱布或类似材料包覆黏贴,等待伤口自行愈合后,再取开纱布等外部包覆固定材料。The existing wound treatment usually involves cleaning and sterilizing the wound first, then applying ointment, wrapping it with gauze or similar materials, and waiting for the wound to heal by itself, and then removing the gauze and other external covering and fixing materials.
这方式对一般小型伤口并没有太大问题,但对大面积伤口或因体质问题较难痊愈的伤员(例如糖尿病患者)而言,伤口的复原时间长,且要多次换药,非常辛苦,而在换药取下纱布时,常会因纱布等包覆物与伤口的组织液沾黏结合,使伤口受到拉力而发生再次撕裂的情况,导致伤口再次受损,痊愈的时间就更长。较进步的方式是使用人工皮肤的贴覆,但其改善的效果仍极有限,且无助于伤口的愈合。This method is not a big problem for ordinary small wounds, but for large wounds or wounded patients who are difficult to heal due to physical problems (such as diabetic patients), the recovery time of the wound is long, and the dressing needs to be changed many times, which is very laborious. However, when the dressing is changed and the gauze is removed, the wrapping such as the gauze is often combined with the tissue fluid of the wound, causing the wound to be pulled and torn again, causing the wound to be damaged again and taking longer to heal. A more advanced method is to use artificial skin covering, but its improvement effect is still extremely limited, and it does not help wound healing.
本发明即在克服现有此领域的缺失,提供一种创新的伤口敷料结构组成,可同时达到辅助向血管增生及活化细胞,加速伤口复原,减少疤痕,而撕开剥离容易等绝佳的特性。为实现上述目的,本发明的一种伤口敷料结构组成,尤其指一种具有抗菌抗病毒效果的复合细胞活化增生材料组成,主要包括三层结构体的组合,其中结构体一为基材,由一种包括但不限于纤维、纱线与织品类所制成的不沾黏基础材料,结构体二为纳米金溅镀层,结合于基材的一侧面,结构体三为吸血棉片,结合于基材的另一侧面。The present invention overcomes the existing deficiencies in this field, and provides an innovative wound dressing structure, which can simultaneously achieve the excellent characteristics of assisting the proliferation of blood vessels and activating cells, accelerating wound recovery, reducing scars, and being easy to tear and peel. . In order to achieve the above purpose, a wound dressing structure of the present invention, especially a composite cell activation and proliferation material with antibacterial and antiviral effects, mainly includes a combination of three-layer structures, wherein the first structure is a base material, which is composed of three layers. A non-stick base material including but not limited to fibers, yarns and fabrics, the second structure is a nano-gold sputtering layer, which is combined with one side of the base material, and the third structure is a blood-sucking cotton sheet, combined with the other side of the substrate.
本发明的使用方式为以纳米金溅镀层朝向伤口,通过纳米金具有的活化细胞,帮助血管增生的效果,可助益伤口的复原,而中间基材通过其不沾黏的特性,配合另一侧吸血棉片的组合,可顺利吸附组织液于棉片,避免伤口沾黏,便于敷材与伤口分离,达到俾益伤口愈合的功效。The use method of the present invention is to use the nano-gold sputtering layer to face the wound, through the effect of activating cells of the nano-gold to help the blood vessels to proliferate, which can help the recovery of the wound, and the intermediate base material, through its non-stick properties, cooperates with another The combination of the side blood-sucking cotton pads can smoothly absorb tissue fluid on the cotton pads, prevent the wound from sticking, and facilitate the separation of the dressing material from the wound to achieve the effect of benefiting wound healing.
进一步的,基材为一种包括但不限于纤维、纱线与织品类所制成的基础材料。Further, the substrate is a basic material including but not limited to fibers, yarns and fabrics.
进一步的,基材为与伤口组织液不造成沾黏的材料结构,包含但不限于网状构造。Further, the base material is a material structure that does not cause adhesion to the wound tissue fluid, including but not limited to a mesh structure.
进一步的,于基材和吸血棉片之间,还结合以一层多金属纳米溅镀层。Further, a multi-metal nano sputtering layer is combined between the base material and the blood-sucking cotton sheet.
进一步的,多金属纳米溅镀层的金属,包含但不限于银、铜、钛。Further, the metals of the multi-metal nano sputtering layer include but are not limited to silver, copper, and titanium.
下面结合附图和具体实施方式对本发明作进一步详细的说明。The present invention will be described in further detail below with reference to the accompanying drawings and specific embodiments.
图1为本发明的材料组合结构的剖面示意图;Fig. 1 is the cross-sectional schematic diagram of the material combination structure of the present invention;
图2为本发明的应用实施例示意图。FIG. 2 is a schematic diagram of an application embodiment of the present invention.
附图标记说明Description of reference numerals
1伤口敷料结构组成;1 Wound dressing structure composition;
11基材;11 substrates;
12纳米金溅镀层;12nm gold sputtering layer;
13吸血棉片;13 blood-sucking cotton pads;
2多金属纳米溅镀层。2 Multi-metal nano-sputtering layer.
请参阅图1所示,本发明为一种伤口敷料结构组成1,主要包括三层结构体,其中结构体一为基材11,由一种包括但不限于纤维、纱线与织品类所制成的基础材料,特别是使用包括但不限于网状构造,且为与伤口组织液不造成沾黏的材料,结构体二为纳米金溅镀层12,通过溅镀方式将纳米金结合于基材11的一侧面而成,结构体三为吸血棉片13,结合于基材的另一侧面11。Please refer to FIG. 1 , the present invention is a wound dressing structure 1, which mainly includes a three-layer structure, wherein the first structure is a substrate 11, which is made of a kind of material including but not limited to fibers, yarns and fabrics. The basic material formed, especially the use including but not limited to the mesh structure, and the material that does not cause adhesion with the wound tissue fluid, the second structure is the nano-gold sputtering layer 12, and the nano-gold is bonded to the substrate 11 by sputtering. It is formed from one side of the base material, and the third structure is a blood-sucking cotton sheet 13, which is combined with the other side 11 of the base material.
使用时,本发明的伤口敷料结构组成1是以纳米金溅镀层12朝向伤口,通过纳米金具有的活化细胞,帮助血管增生的效果,可助益伤口的复原,而中间基材11透过其不沾黏的特性,配合另一侧吸血棉片13的组合,可顺利吸附从伤口渗出的组织液于吸血棉片13内,乃可避免伤口与基材11沾黏,而能便利伤口敷料结构组成1整体与伤口分离,达到俾益伤口愈合的功效。When in use, the wound dressing structure composition 1 of the present invention is that the nano-gold sputtering layer 12 faces the wound, and the nano-gold has the effect of activating cells to help the proliferation of blood vessels, which can help the recovery of the wound, and the intermediate substrate 11 passes through it. The non-stick properties, combined with the combination of the other side of the blood-sucking cotton sheet 13, can smoothly absorb the tissue fluid exuded from the wound into the blood-sucking cotton sheet 13, which can prevent the wound from sticking to the substrate 11, and can facilitate the structure of the wound dressing. Composition 1 is separated from the wound as a whole to achieve the effect of benefiting wound healing.
本发明的一项特征在于利用纳米金来加速伤口的治疗,对于金元素具有活化细胞及辅助血管增生的效果,在许多研究中已获得证实。但已知的应用领域均局限于使用金属键结合的块状金或薄膜金结构,其虽然可以产生一定的细胞活化效果,但仍然有限,相较于本发明以纳米金溅镀层12结构所具有的活化效应,具有相当大的差异,其主要原因为,由于自由电子在块状金或薄膜金中,可以自由的活动,但在纳米金粒子的表面时,会受到很大的限制,在无法自由活动的情况下,就较容易释出,而此释出的电子对外部细胞和血管活化,更为有效,另外,其也具有非绝对强效的适度效果的抗菌能力,使本发明所运用的纳米金溅镀层12具有抗菌效果但不伤害细胞的独特性功效,而非常适合用在人类伤口,同时需要防止细菌感染,以及协助血管增生与细胞活化的应用上。A feature of the present invention is to use nano-gold to accelerate wound treatment, and gold has the effect of activating cells and assisting blood vessel proliferation, which has been confirmed in many studies. However, the known application fields are limited to the use of metal-bonded bulk gold or thin-film gold structures. Although they can produce a certain cell activation effect, they are still limited. Compared with the nano-gold sputtering layer 12 structure in the present invention, There are considerable differences in the activation effect of the gold nanoparticles. The main reason is that free electrons can move freely in bulk gold or thin film gold, but they will be greatly restricted when they are on the surface of gold nanoparticles. In the case of free movement, it is easier to release, and the released electrons are more effective for the activation of external cells and blood vessels. In addition, it also has a moderate effect of antibacterial ability that is not absolutely strong, so that the present invention can be used. The nano-gold sputtering layer 12 has the unique effect of antibacterial effect but does not harm cells, and is very suitable for use in human wounds, which need to prevent bacterial infection, as well as assist vascular proliferation and cell activation applications.
请参阅图2所示,本发明可在基材11和吸血棉片13之间再结合以一层多金属纳米溅镀层2,其包含但不限于金属银、铜、钛等纳米金属的复合型溅镀层线结构,此多金属纳米溅镀层2可运用不同金属间氧化还原电位差,于其表面形成电子海,进而成为电子盾,提供对外部之抗菌抗病毒效果,此详细技术内容可参见于同申请人于2020年12月19日申请的PCT申请PCT/CN2020/129986号,可增加本发明以伤口敷料结构组成1的内层纳米金溅镀层12加速治疗伤口时,隔绝外部细菌和病毒的功效。Please refer to FIG. 2 , in the present invention, a multi-metal nano-sputtering layer 2 can be combined between the substrate 11 and the blood-sucking cotton sheet 13, which includes but is not limited to a composite type of nano-metal such as silver, copper, and titanium. The sputtered layer line structure, the multi-metal nano-sputtered layer 2 can use the redox potential difference between different metals to form an electron sea on its surface, and then become an electronic shield, providing antibacterial and antiviral effects on the outside, the detailed technical content can be found in The same PCT application No. PCT/CN2020/129986 filed by the applicant on December 19, 2020, can increase the inner layer nano-gold sputtering layer 12 composed of the wound dressing structure 1 of the present invention to accelerate the treatment of wounds, isolate external bacteria and viruses. effect.
综上,本发明所完成的加速伤口愈合的抗菌抗病毒易剥离伤口敷料结构组成1,首创使用纳米金的方式,同时兼具恰到好处的抑菌及快速伤口愈合的功能,及纳米金独特表面电子释出活性,可提供伤口复原最佳的物理性机能,并配合易剥离基材,以及外层的吸血棉片、多金属纳米溅镀层的物理性抗菌机制,可在不牵涉到任何化学药剂下,达到完美的抗菌与伤口的加速愈合,同时具备易剥离的特性,获致更佳的产业利用价值。To sum up, the structure of the antibacterial, antiviral, and easy-to-peel wound dressing that accelerates wound healing completed by the present invention is composed of 1. It is the first method to use nano-gold, which has both the proper antibacterial and rapid wound-healing functions, and the unique surface electrons of nano-gold. The release activity can provide the best physical function for wound recovery, and with the easy-to-peel substrate, as well as the physical antibacterial mechanism of the outer layer of blood-sucking cotton sheet and multi-metal nano-sputtering layer, it can be used without involving any chemicals. , to achieve perfect antibacterial and accelerated wound healing, and at the same time, it has the characteristics of easy peeling, and obtains better industrial utilization value.
Claims (5)
- 一种伤口敷料的结构组成,主要包括三层结构体,其特征在于,结构体一为基材,结构体二为纳米金溅镀层,结合于基材的一侧面而成,结构体三为吸血棉片,结合于基材的另一侧面。The structure of a wound dressing mainly includes three-layer structures, characterized in that the first structure is a base material, the second structure is a nano-gold sputtering layer, which is formed by combining with one side of the base material, and the third structure is blood-sucking The cotton piece is bonded to the other side of the substrate.
- 如权利要求1所述的一种伤口敷料的结构组成,其特征在于,基材为一种包括但不限于纤维、纱线与织品类所制成的基础材料。The structure of a wound dressing according to claim 1, wherein the base material is a base material including but not limited to fibers, yarns and fabrics.
- 如权利要求1所述的一种伤口敷料的结构组成,其特征在于,基材为与伤口组织液不造成沾黏的材料结构,包含但不限于网状构造。The structure of a wound dressing according to claim 1, wherein the base material is a material structure that does not adhere to wound tissue fluid, including but not limited to a mesh structure.
- 如权利要求1所述的一种伤口敷料的结构组成,其特征在于,于基材和吸血棉片之间,还结合以一层多金属纳米溅镀层。The structure composition of a wound dressing according to claim 1, wherein a multi-metal nano-sputtering layer is also combined between the base material and the blood-sucking cotton sheet.
- 如权利要求4所述的一种伤口敷料的结构组成,其特征在于,多金属纳米溅镀层的金属,包含但不限于银、铜、钛。The structural composition of a wound dressing according to claim 4, wherein the metal of the multi-metal nano-sputtering layer includes but is not limited to silver, copper, and titanium.
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TW200423973A (en) * | 2003-05-02 | 2004-11-16 | Nat Univ Chung Hsing | Wound dressing |
US20140364819A1 (en) * | 2013-06-10 | 2014-12-11 | Ultramend, Inc. | Nano-enhanced wound dressing |
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CN210019931U (en) * | 2018-12-18 | 2020-02-07 | 生命之星国际股份有限公司 | Wound dressing with indication function |
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2021
- 2021-01-12 WO PCT/CN2021/071191 patent/WO2022150947A1/en active Application Filing
- 2021-01-12 CN CN202180040538.3A patent/CN116583307A/en active Pending
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TW200423973A (en) * | 2003-05-02 | 2004-11-16 | Nat Univ Chung Hsing | Wound dressing |
US20140364819A1 (en) * | 2013-06-10 | 2014-12-11 | Ultramend, Inc. | Nano-enhanced wound dressing |
CN204092334U (en) * | 2014-09-16 | 2015-01-14 | 卢欣恺 | The wound dressing structure of tool sterilizing function |
CN106139224A (en) * | 2016-07-20 | 2016-11-23 | 国家纳米科学中心 | A kind of containing nanometer gold antiseptic dressing and preparation method thereof |
CN108686253A (en) * | 2018-06-21 | 2018-10-23 | 东莞市联洲知识产权运营管理有限公司 | A kind of preparation method of high-efficiency antimicrobial medical dressing |
CN210019931U (en) * | 2018-12-18 | 2020-02-07 | 生命之星国际股份有限公司 | Wound dressing with indication function |
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