WO2022147288A1 - Lotion pour bébé - Google Patents
Lotion pour bébé Download PDFInfo
- Publication number
- WO2022147288A1 WO2022147288A1 PCT/US2021/065735 US2021065735W WO2022147288A1 WO 2022147288 A1 WO2022147288 A1 WO 2022147288A1 US 2021065735 W US2021065735 W US 2021065735W WO 2022147288 A1 WO2022147288 A1 WO 2022147288A1
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- WO
- WIPO (PCT)
- Prior art keywords
- composition
- skin care
- care composition
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- composition comprises
- Prior art date
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- 239000006210 lotion Substances 0.000 title claims abstract description 10
- 239000000203 mixture Substances 0.000 claims abstract description 160
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims description 21
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 18
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 14
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims description 14
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 12
- 239000003205 fragrance Substances 0.000 claims description 10
- 235000012424 soybean oil Nutrition 0.000 claims description 10
- 235000011187 glycerol Nutrition 0.000 claims description 9
- 239000010514 hydrogenated cottonseed oil Substances 0.000 claims description 9
- SZAMSYKZCSDVBH-CLFAGFIQSA-N [(z)-octadec-9-enyl] (z)-docos-13-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCCCCCC(=O)OCCCCCCCC\C=C/CCCCCCCC SZAMSYKZCSDVBH-CLFAGFIQSA-N 0.000 claims description 8
- 150000001875 compounds Chemical class 0.000 claims description 8
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 8
- REZZEXDLIUJMMS-UHFFFAOYSA-M dimethyldioctadecylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC REZZEXDLIUJMMS-UHFFFAOYSA-M 0.000 claims description 8
- 229940073551 distearyldimonium chloride Drugs 0.000 claims description 8
- 229940120511 oleyl erucate Drugs 0.000 claims description 8
- 229940043707 polyglyceryl-6 distearate Drugs 0.000 claims description 8
- 229960001295 tocopherol Drugs 0.000 claims description 8
- 229930003799 tocopherol Natural products 0.000 claims description 8
- 235000010384 tocopherol Nutrition 0.000 claims description 8
- 239000011732 tocopherol Substances 0.000 claims description 8
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 8
- NKJOXAZJBOMXID-UHFFFAOYSA-N 1,1'-Oxybisoctane Chemical compound CCCCCCCCOCCCCCCCC NKJOXAZJBOMXID-UHFFFAOYSA-N 0.000 claims description 7
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 7
- 235000004433 Simmondsia californica Nutrition 0.000 claims description 7
- 235000019445 benzyl alcohol Nutrition 0.000 claims description 7
- 229960000541 cetyl alcohol Drugs 0.000 claims description 7
- 229940052366 colloidal oatmeal Drugs 0.000 claims description 7
- 150000002148 esters Chemical class 0.000 claims description 7
- 235000010241 potassium sorbate Nutrition 0.000 claims description 7
- 239000004302 potassium sorbate Substances 0.000 claims description 7
- 229940069338 potassium sorbate Drugs 0.000 claims description 7
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 7
- 235000010234 sodium benzoate Nutrition 0.000 claims description 7
- 239000004299 sodium benzoate Substances 0.000 claims description 7
- 239000011780 sodium chloride Substances 0.000 claims description 7
- 229940048081 trisodium ethylenediamine disuccinate Drugs 0.000 claims description 7
- QEHXDDFROMGLSP-VDBFCSKJSA-K trisodium;(2s)-2-[2-[[(1s)-1-carboxy-2-carboxylatoethyl]amino]ethylamino]butanedioate Chemical compound [Na+].[Na+].[Na+].OC(=O)C[C@@H](C([O-])=O)NCCN[C@H](C([O-])=O)CC([O-])=O QEHXDDFROMGLSP-VDBFCSKJSA-K 0.000 claims description 7
- 239000004471 Glycine Substances 0.000 claims description 6
- 235000013871 bee wax Nutrition 0.000 claims description 6
- 239000012166 beeswax Substances 0.000 claims description 6
- 240000001432 Calendula officinalis Species 0.000 claims description 5
- 229940002386 calendula officinalis extract Drugs 0.000 claims description 3
- 239000006071 cream Substances 0.000 claims description 3
- 244000044822 Simmondsia californica Species 0.000 claims 2
- 239000004615 ingredient Substances 0.000 abstract description 12
- 239000000463 material Substances 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 7
- 206010013786 Dry skin Diseases 0.000 abstract description 4
- 230000037336 dry skin Effects 0.000 abstract description 4
- LQIAZOCLNBBZQK-UHFFFAOYSA-N 1-(1,2-Diphosphanylethyl)pyrrolidin-2-one Chemical compound PCC(P)N1CCCC1=O LQIAZOCLNBBZQK-UHFFFAOYSA-N 0.000 abstract description 3
- 241000196324 Embryophyta Species 0.000 description 14
- 239000003795 chemical substances by application Substances 0.000 description 10
- 230000003750 conditioning effect Effects 0.000 description 7
- 239000003974 emollient agent Substances 0.000 description 6
- 241000221095 Simmondsia Species 0.000 description 5
- 239000003995 emulsifying agent Substances 0.000 description 5
- 239000003755 preservative agent Substances 0.000 description 5
- 239000004909 Moisturizer Substances 0.000 description 4
- 230000001333 moisturizer Effects 0.000 description 4
- 230000002335 preservative effect Effects 0.000 description 4
- 239000003381 stabilizer Substances 0.000 description 4
- 235000004443 Ricinus communis Nutrition 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 239000002738 chelating agent Substances 0.000 description 3
- 239000003906 humectant Substances 0.000 description 3
- 239000002562 thickening agent Substances 0.000 description 3
- 235000015112 vegetable and seed oil Nutrition 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 239000001993 wax Substances 0.000 description 3
- 244000180278 Copernicia prunifera Species 0.000 description 2
- 235000010919 Copernicia prunifera Nutrition 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 244000020551 Helianthus annuus Species 0.000 description 2
- 235000003222 Helianthus annuus Nutrition 0.000 description 2
- 229940119162 calendula officinalis flower extract Drugs 0.000 description 2
- 230000002500 effect on skin Effects 0.000 description 2
- 231100000344 non-irritating Toxicity 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- -1 pH adjustors Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- AJBZENLMTKDAEK-UHFFFAOYSA-N 3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-4,9-diol Chemical compound CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3O)(C)C2CCC1C1C3(C)CCC1C(=C)C AJBZENLMTKDAEK-UHFFFAOYSA-N 0.000 description 1
- 235000003880 Calendula Nutrition 0.000 description 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 241001553290 Euphorbia antisyphilitica Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 235000016856 Palma redonda Nutrition 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- 235000003846 Ricinus Nutrition 0.000 description 1
- 241000322381 Ricinus <louse> Species 0.000 description 1
- 240000000528 Ricinus communis Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000000828 canola oil Substances 0.000 description 1
- 235000019519 canola oil Nutrition 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000000774 hypoallergenic effect Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 230000037067 skin hydration Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
Definitions
- This document relates to materials and methods for formulating skin care compositions suitable for use on babies and toddlers.
- this document relates to materials and methods for formulating lotion compositions that contain natural ingredients, are not irritating to babies’ skin, and can be used to moisturize and soothe dry skin.
- Skin care products e.g., lotions and creams designed for adult use often are not suitable for use with small children.
- compositions that are suitable for use on young children.
- the compositions provided herein contain natural and safe ingredients, resulting in products that are low (or non-) irritating to babies’ skin.
- the compositions provided herein can be used to reduce dry skin, increase smoothness and moisturization of skin, and reduce skin irritation.
- this document features a skin care composition that contains distearyldimonium chloride, dicaprylyl ether, oleyl erucate, Glycine soya oil, a Calendula officinalis extract, hydrogenated cottonseed oil, and glycerin.
- the composition can contain from about 0.05 to about 50 % w/w distearyldimonium chloride.
- the composition can contain from about 0.15 to about 15 % w/w dicaprylyl ether.
- the composition can contain from about 0.15 to about 15 % w/w oleyl erucate.
- the composition can contain from about 0.5 to about 50 % w/w G. soya oil.
- the composition can contain from about 0.00125 to about 0.125 % w/w C. officinalis extract.
- the composition can further contain tocopherol.
- the composition can contain from about 0.00005 to about 0.005 % w/w tocopherol.
- the composition can contain from about 0.075 to 7.5 % w/w hydrogenated cottonseed oil.
- the composition can contain from about 1 to about 50 % w/w glycerin.
- the composition can further contain cetyl alcohol.
- the composition can contain from about 0.3 to about 30 % w/w cetyl alcohol.
- the composition can further contain polyglyceryl-6 distearate.
- the composition can contain from about 0.1 to about 10 % w/w polyglyceryl-6 distearate.
- the composition can further contain colloidal oatmeal.
- the composition can contain from about 0.1 to about 10 % w/w colloidal oatmeal.
- the composition can further contain benzyl alcohol.
- the composition can contain from about 0.05 to about 5 % w/w benzyl alcohol.
- the composition can further contain jojoba esters.
- the composition can contain from about 0.035 to about 3.5 % w/w jojoba esters.
- the composition can further contain sodium benzoate.
- the composition can contain from about 0.016 to about 1.6 % w/w sodium benzoate.
- the composition can further contain polyglyceryl-3 beeswax.
- the composition can contain from about 0.014 to about 1.4 % w/w polyglyceryl-3 beeswax.
- the composition can further contain potassium sorbate.
- the composition can contain from about 0.008 to about 0.8 % w/w potassium sorbate.
- the composition can further contain trisodium ethylenediamine disuccinate.
- the composition can contain from about 0.005 to about 0.5 % w/w trisodium ethylenediamine disuccinate.
- the composition can further contain sodium chloride.
- the can contain composition can contain from about 0.005 to about 0.5 % w/w sodium chloride.
- the composition can further contain one or more fragrance compounds.
- the composition can contain from about 0.07 to about 7 % w/w of said one or more fragrance compounds.
- the composition can have a viscosity of about 1 x 10 5 to about 7 x 10 5 centipoise.
- the composition can be formulated as a lotion or cream.
- compositions containing ingredients that are safe for use on young children are low irritating (e.g., nonirritating) and hypoallergenic, and typically contain multiple natural (plant-derived) ingredients such as glycerin, Calendula officinalis flower extract, and Glycine soya oil. Moreover, the compositions provided herein do not contain petrolatum, which is sometimes used as a barrier or moisturizing agent.
- compositions provided herein can contain any appropriate ingredients, including, without limitation, one or more surfactants, humectants, moisturizers, preservatives, fragrances, pH adjustors, chelating agents, emollients, skin conditioning agents, thickening agents, flow agents, emulsifiers, and stabilizers.
- surfactants humectants
- moisturizers preservatives
- fragrances pH adjustors
- chelating agents emollients
- emollients e.g., glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycerin, glycer
- Distearyldimonium chloride is a plant-derived skin conditioner and emulsifier.
- the compositions provided herein can contain distearyldimonium chloride in an amount from about 0.5 to about 50 % w/w (e.g., from about 0.5 to about 2.5 % w/w, from about 2.5 to about 5 % w/w, from about 5 to about 10 % w/w, from about 10 to about 25 % w/w, or from about 25 to about 50 % w/w).
- distearyldimonium chloride can be present in a composition provided herein in an amount from about 2.5 to about 7.5 % w/w (e.g., from about 4 to about 6 % w/w).
- Dicaprylyl ether is a plant-derived skin conditioning agent and emollient that can be plant-derived.
- the compositions provided herein can contain dicarpylyl ether in an amount from about 0.15 to about 15 % w/w (e.g., from about 0.15 to about 0.5 % w/w, from about 0.5 to about 3 % w/w, from about 3 to about 5 % w/w, from about 5 to about 10 % w/w, or from about 10 to about 15 % w/w).
- dicaprylyl ether can be present in a composition provided herein in an amount from about 0.75 to about 2.25 % w/w (e.g., from about 1.2 to about 1.8 % w/w).
- Oleyl erucate is another plant-derived skin conditioning agent and emollient.
- the compositions provided herein can contain oleyl erucate in an amount from about 0.15 to about 15 % w/w (e.g., from about 0.15 to about 0.5 % w/w, from about 0.5 to about 3 % w/w, from about 3 to about 5 % w/w, from about 5 to about 10 % w/w, or from about 10 to about 15 % w/w).
- oleyl erucate can be present in a composition provided herein in an amount from about 0.75 to about 2.25 % w/w (e.g., from about 1.2 to about 1.8 % w/w).
- Glycine soya oil is a plant-derived skin conditioning agent that can help to moisturize and soften skin.
- the compositions provided herein can contain G. soya oil in an amount from about 0.5 to about 50 % w/w (e.g., from about 0.5 to about 1 % w/w, from about 1 to about 3 % w/w, from about 3 to about 5 % w/w, from about 5 to about 10 % w/w, from about 10 to about 30 % w/w, or from about 30 to about 50 % w/w).
- G. soya oil can be present in a composition provided herein in an amount from about 3 to about 9 % w/w (e.g., from about 5 to about 7 % w/w).
- Calendula officinalis flower extract is a moisturizer and emollient that can condition and soothe the skin.
- the compositions provided herein can contain a C. officinalis extract in an amount from about 0.00125 to about 0.125 % w/w (e.g., from about 0.00125 to about 0.005 % w/w, from about 0.005 to about 0.01 % w/w, from about 0.01 to about 0.05 % w/w, from about 0.05 to about 0.1 % w/w, or from about 0.1 to about 0.125 % w/w).
- a C. officinalis flower extract can be present in a composition provided herein in an amount from about 0.006 to about 0.02 % w/w (e.g., from about 0.001 to about 0.0015 % w/w).
- Tocopherol is an emollient and skin conditioning agent.
- the compositions provided herein can contain tocopherol in an amount from about 0.00005 to about 0.005 % w/w (e.g., from about 0.00005 to about 0.0001 % w/w, from about 0.0001 to about 0.0005 % w/w, from about 0.0005 to about 0.001 % w/w, or from about 0.001 to about 0.005 % w/w).
- tocopherol can be present in a composition provided herein in an amount from about 0.00025 to about 0.00075 % w/w (e.g., from about 0.0004 to about 0.0006 % w/w).
- Hydrogenated cottonseed oil is a plant-derived oil that can moisturize, condition, and soften skin.
- the compositions provided herein can contain hydrogenated cottonseed oil in an amount from about 0.075 to about 7.5 % w/w (e.g., from about 0.075 to about 0.5 % w/w, from about 0.5 to about 1 % w/w, from about 1 to about 3 % w/w, or from about 3 to about 7.5 % w/w).
- hydrogenated cottonseed oil can be present in a composition provided herein in an amount from about 0.38 to about 1.1 % w/w (e.g., from about 0.6 to about 0.9 % w/w).
- Glycerin is a humectant and skin conditioning agent that can draw moisture into the skin, and can be plant-derived.
- the compositions provided herein can contain glycerin in an amount from about 1 to about 50 % w/w (e.g., from about 1 to about 3 % w/w, from about 3 to about 5 % w/w, from about 5 to about 10 % w/w, from about 10 to about 15 % w/w, from about 15 to about 25 % w/w, or from about 25 to about 50 % w/w).
- glycerin can be present in a composition provided herein in an amount from about 6 to about 18 % w/w (e.g., from about 9 to about 15 % w/w).
- Cetyl alcohol is an emulsifier that can be plant-derived.
- the compositions provided herein can contain cetyl alcohol in an amount from about 0.3 to about 30 % w/w (e.g., from about 0.3 to about 1 % w/w, from about 1 to about 3 % w/w, from about 3 to about 5 % w/w, from about 5 to about 15 % w/w, or from about 15 to about 30 % w/w).
- cetyl alcohol can be present in a composition provided herein in an amount from about 1.5 to about 4.5 % w/w (e.g., from about 2 to about 4 % w/w).
- Polyglyceryl-6 distearate is another emulsifier that can be plant-derived.
- the compositions provided herein can contain polyglyceryl-6 distearate in an amount from about 0. 1 to about 10 % w/w (e.g., from about 0. 1 to about 0.5 % w/w, from about 0.5 to about 1 % w/w, from about 1 to about 3 % w/w, or from about 3 to about 10 % w/w).
- polyglyceryl-6 distearate can be present in a composition provided herein in an amount from about 0.7 to about 2.1 % w/w (e.g., from about 1. 1 to about 1.7 % w/w).
- Polyglyceryl-3 beeswax also is an emulsifier that can be plant-derived.
- the compositions provided herein can contain polyglyceryl-3 beeswax in an amount from about 0.014 to about 1.4 % w/w (e.g., from about 0.014 to about 0.1 % w/w, from about 0.1 to about 0.2 % w/w, from about 0.2 to about 0.7 % w/w, or from about 0.7 to about 1.4 % w/w).
- polyglyceryl-6 distearate can be present in a composition provided herein in an amount from about 0.07 to about 0.21 % w/w (e.g., from about 0. 12 to about 0. 16 % w/w).
- Jojoba esters are plant-derived stabilizers and thickening agents that also can serve as moisturizers.
- the compositions provided herein can contain jojoba esters in an amount from about 0.035 to about 3.5 % w/w (e.g., from about 0.035 to about 0.1 % w/w, from about 0.1 to about 0.3 % w/w, from about 0.3 to about 0.5 % w/w, from about 0.5 to about 2 % w/w, or from about 2 to about 3.5 % w/w).
- jojoba esters can be present in a composition provided herein in an amount from about 0.
- colloidal oatmeal is a skin conditioner and soother.
- the compositions provided herein can contain colloidal oatmeal in an amount from about 0. 1 to about 10 % w/w (e.g., from about 0.1 to about 0.5 % w/w, from about 0.5 to about 1 % w/w, from about 1 to about 3 % w/w, or from about 3 to about 10 % w/w).
- colloidal oatmeal can be present in a composition provided herein in an amount from about 0.5 to about 1.5 % w/w (e.g., from about 0.8 to about 1.2 % w/w).
- Benzyl alcohol is a preservative.
- the compositions provided herein can contain benzyl alcohol in an amount from about 0.05 to about 5 % w/w (e.g., from about 0.05 to about 0.1 % w/w, from about 0. 1 to about 0.5 % w/w, from about 0.5 to about 1 % w/w, from about 1 to about 3 % w/w, or from about 3 to about 5 % w/w).
- benzyl alcohol can be present in a composition provided herein in an amount from about 0.25 to about 0.75 % w/w (e.g., from about 0.4 to about 0.6 % w/w).
- the compositions provided herein can contain sodium benzoate in an amount from about 0.016 to about 1.6 % w/w (e.g., from about 0.016 to about 0.05 % w/w, from about 0.05 to about 0.1 % w/w, from about 0.1 to about 0.2 % w/w, from about 0.2 to about 1 % w/w, or from about 1 to about 1.6 % w/w).
- sodium benzoate can be present in a composition provided herein in an amount from about 0.08 to about 0.24 % w/w (e.g., from about 0. 12 to about 0.2 % w/w).
- Potassium sorbate also is a preservative.
- the compositions provided herein can contain potassium sorbate in an amount from about 0.008 to about 0.8 % w/w (e.g., from about 0.008 to about 0.05 % w/w, from about 0.05 to about 0.1 % w/w, from about 0. 1 to about 0.3 % w/w, from about 0.3 to about 0.5 % w/w, or from about 0.5 to about 0.8 % w/w).
- potassium sorbate can be present in a composition provided herein in an amount from about 0.04 to about 0.12 % w/w (e.g., from about 0.07 to about 0.09 % w/w).
- Trisodium ethylenediamine disuccinate is a plant-derived chelating agent.
- the compositions provided herein can contain trisodium ethylenediamine disuccinate in an amount from about 0.005 to about 0.5 % w/w (e.g., from about 0.005 to about 0.01 % w/w, from about 0.01 to about 0.05 % w/w, from about 0.05 to about 0.1 % w/w, from about 0. 1 to about 0.3 % w/w, or from about 0.3 to about 0.5 % w/w).
- trisodium ethylenediamine disuccinate can be present in a composition provided herein in an amount from about 0.03 to about 0.09 % w/w (e.g., from about 0.05 to about 0.07 % w/w).
- Sodium chloride can serve as a stabilizer.
- the compositions provided herein can contain sodium chloride in an amount from about 0.005 to about 0.5 % w/w (e.g., from about 0.005 to about 0.01 % w/w, from about 0.01 to about 0.05 % w/w, from about 0.05 to about 0.1 % w/w, from about 0.1 to about 0.3 % w/w, or from about 0.3 to about 0.5 % w/w).
- sodium chloride can be present in a composition provided herein in an amount from about 0.025 to about 0.075 % w/w (e.g., from about 0.04 to about 0.06 % w/w).
- the compositions provided herein also can contain one or more fragrance compounds (e.g., one or more plant-based fragrance compounds).
- the compositions provided herein can contain one or more fragrance compounds in an amount from about 0.07 to about 7 % w/w (e.g., from about 0.07 to about 0.1 % w/w, from about 0.1 to about 0.5 % w/w, from about 0.5 to about 1 % w/w, from about 1 to about 4 % w/w, or from about 4 to about 7 % w/w).
- fragrance compounds can be present in a composition provided herein in an amount from about 0.35 to about 1 % w/w (e.g., from about 0.6 to about 0.8 % w/w).
- compositions provided herein can include water, which can make up the remainder of the composition apart from the other ingredients.
- the compositions provided herein can contain water in an amount from about 30 to about 95 % w/w (e.g., from about 30 to about 40 % w/w, from about 40 to about 50 % w/w, from about 50 to about 60 % w/w, from about 60 to about 70 % w/w, from about 70 to about 80 % w/w, or from about 80 to about 95 % w/w).
- water can be present in a composition provided herein in an amount from about 33 to about 99 % w/w (e.g., about 50 to about 80 % w/w).
- compositions provided herein can include distearyldimonium chloride, dicaprylyl ether, oleyl erucate, Glycine soya oil, a Calendula officinalis extract, tocopherol, hydrogenated cottonseed oil, and glycerin.
- a composition provided herein also can include any one or more of the other ingredients listed above.
- composition provided herein can further include any other appropriate ingredient (e.g., any other suitable surfactant, humectant, moisturizer, preservative, fragrance, pH adjustor, chelating agent, emollient, stabilizer, skin conditioning agent, thickening agent, or flow agent).
- any other appropriate ingredient e.g., any other suitable surfactant, humectant, moisturizer, preservative, fragrance, pH adjustor, chelating agent, emollient, stabilizer, skin conditioning agent, thickening agent, or flow agent.
- any of the above ingredients can be substituted with any other appropriate ingredient.
- the hydrogenated cottonseed oil and/or Glycine soya oil can be replaced by Ricinus commuis (castor) seed oil, hydrogenated castor oil, and Copernicia cerifera (carnauba) wax; vegetable oil; or canola oil, Ricinus communis (castor) seed oil, polyhydroxystearic acid, Euphorbia cerifera (candililla) wax, Helianthus annuus (sunflower) seed wax, and tocopheryl acetate.
- compositions described herein can have any appropriate pH.
- the pH of the compositions is such that they are low irritating (e.g., non-irritating) to the skin or eyes.
- a composition provided herein can have a pH of about 5 to about 6 (e.g., from about 5.0 to about 5.3, from about 5.2 to about 5.5, from about 5.4 to about 5.7, or from about 5.7 to about 6.0).
- compositions provided herein also can have any appropriate viscosity.
- a lotion composition provided herein can have a viscosity from about 1 x 10 5 to about 7 x 10 5 centipoise (cps) (e.g., from about 1 x 10 5 to about 3 x 10 5 cps, from about 3 x 10 5 to about 5 x 10 5 cps, or from about 5 x 10 5 to about 7 x 10 5 ).
- cps centipoise
- a baby lotion composition was prepared according to the formulation in TABLE 1, and was tested in a blind consumer study of 91 participants selected from the concept study based at least in part on their willingness to test the product for a two week period. Participants completed a survey about 40 minutes after placing the lotion on their child’s leg(s). More than 95% of the participants stated that the composition was gentle on their children’s skin, and about 90% of participants stated that the composition left their child’s skin feeling nourished and provided relief from dry skin. Similar results were obtained when the composition was pediatrician and dermatologist tested. TABLE 1
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Abstract
L'invention concerne des matériaux et des procédés de formulation de compositions de soin cutané appropriées pour être utilisées sur des bébés et des jeunes enfants. Par exemple, ce document fournit des matériaux et des procédés pour formuler des compositions de lotion qui contiennent des ingrédients naturels, ne sont pas irritantes pour la peau des bébés, et peuvent être utilisées pour hydrater et lutter contre le dessèchement de la peau.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063133053P | 2020-12-31 | 2020-12-31 | |
US63/133,053 | 2020-12-31 |
Publications (1)
Publication Number | Publication Date |
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WO2022147288A1 true WO2022147288A1 (fr) | 2022-07-07 |
Family
ID=82120255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2021/065735 WO2022147288A1 (fr) | 2020-12-31 | 2021-12-30 | Lotion pour bébé |
Country Status (3)
Country | Link |
---|---|
US (1) | US20220202672A1 (fr) |
TW (1) | TW202241382A (fr) |
WO (1) | WO2022147288A1 (fr) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110015279A1 (en) * | 2008-03-26 | 2011-01-20 | Sebastian Doerr | Skin care composition |
-
2021
- 2021-12-30 WO PCT/US2021/065735 patent/WO2022147288A1/fr active Application Filing
- 2021-12-30 US US17/565,944 patent/US20220202672A1/en active Pending
- 2021-12-30 TW TW110149721A patent/TW202241382A/zh unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110015279A1 (en) * | 2008-03-26 | 2011-01-20 | Sebastian Doerr | Skin care composition |
Non-Patent Citations (2)
Title |
---|
ANONYMOUS: "Koala Kubs Natural Baby Lotion - Double", EQLIB MEDISPA, 18 April 2021 (2021-04-18), pages 1 - 4, XP055954566, Retrieved from the Internet <URL:https://web.archive.org/web/20210418050002/https://eqiib.ca/produit/produits-pour-bebes-et-enfants/lotion-pour-bebe-naturelle> [retrieved on 20220310] * |
ANONYMOUS: "Waterproof Gel Liner", SHARA COSMETICS, 29 September 2020 (2020-09-29), pages 1 - 2, XP055954538, Retrieved from the Internet <URL:https://web.archive.org/web/20200929204228/https://www.sharacosmetics.com/product-page/waterproof-gel-liner> [retrieved on 20220310] * |
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TW202241382A (zh) | 2022-11-01 |
US20220202672A1 (en) | 2022-06-30 |
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