WO2022127143A1 - 一种一氧化氮浓度的检测装置及一氧化氮浓度检测仪 - Google Patents

一种一氧化氮浓度的检测装置及一氧化氮浓度检测仪 Download PDF

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WO2022127143A1
WO2022127143A1 PCT/CN2021/111992 CN2021111992W WO2022127143A1 WO 2022127143 A1 WO2022127143 A1 WO 2022127143A1 CN 2021111992 W CN2021111992 W CN 2021111992W WO 2022127143 A1 WO2022127143 A1 WO 2022127143A1
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nitric oxide
detection device
circuit
output end
oxide concentration
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PCT/CN2021/111992
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English (en)
French (fr)
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符坚
林仕伟
周义龙
陈汉德
陈宝
林正玺
王玲转
林慧媛
符智豪
黄修彩
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海南聚能科技创新研究院有限公司
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Publication of WO2022127143A1 publication Critical patent/WO2022127143A1/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G01N33/4975—Physical analysis of biological material of gaseous biological material, e.g. breath other than oxygen, carbon dioxide or alcohol, e.g. organic vapours
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means

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  • the present application relates to the technical field of sensor detection circuits, and in particular, to a nitric oxide concentration detection device and a nitric oxide concentration detector.
  • Nitric oxide sensors are used to measure nitric oxide concentration and are widely used in various fields.
  • nitric oxide can be used as a novel noninvasive and easily detectable biomarker for the diagnosis of airway inflammatory diseases. Changes in the concentration of nitric oxide in exhaled breath can reflect the occurrence, condition changes and asthma phenotypes of asthma.
  • the concentration of nitric oxide in exhaled air can be detected by a nitric oxide detection instrument, which is helpful for the diagnosis and treatment of asthma. Evaluate the efficacy of treatment. Due to the low concentration of exhaled nitric oxide, usually at the part per billion (ppb) level, the sensitivity of the detection instrument is relatively high, and the high-precision nitric oxide sensor is expensive. Here comes a series of problems with high testing costs.
  • the purpose of this application is to provide a nitric oxide concentration detection device and a nitric oxide concentration detector for realizing low-cost and high-precision nitric oxide detection.
  • the present application provides a detection device for nitric oxide concentration, including: a plurality of nitric oxide sensors, a power supply circuit and an amplifier circuit;
  • the power supply terminal of each of the nitric oxide sensors is connected to the output terminal of the power supply circuit, the output terminal of each of the nitric oxide sensors is connected to the input terminal of the amplifying circuit, and the output terminal of the amplifying circuit is connected.
  • the terminal is connected with the signal output terminal of the detection device.
  • the number of the nitric oxide sensors is specifically three.
  • the amplifying circuit specifically includes a first amplifying circuit and a second amplifying circuit
  • the input end of one of the first amplifying circuits is correspondingly connected to the output end of one of the nitric oxide sensors, the output end of each of the first amplifying circuits is connected to the input end of the second amplifying circuit, and the The output end of the second amplifying circuit is connected to the signal output end.
  • the nitric oxide sensor is specifically a nitric oxide sensor with an accuracy of 5-20 ppb.
  • the nitric oxide sensor is specifically an electrochemical nitric oxide sensor.
  • it also includes a filter circuit arranged between the output end of the amplifying circuit and the signal output end.
  • the power supply circuit is specifically constructed based on a voltage regulator chip.
  • the present application also provides a nitric oxide concentration detector, which includes the nitric oxide concentration detection device described in any one of the above, and also includes an analog-to-digital conversion circuit and a processor;
  • the input end of the analog-to-digital conversion circuit is connected to the signal output end of the detection device, and the output end of the analog-to-digital conversion circuit is connected to the signal input end of the processor.
  • it also includes a communicator connected to the signal output end of the processor.
  • the communicator is specifically an RS485 communicator.
  • the nitric oxide concentration detection device supplied by the present application supplies power to the nitric oxide sensor through a power supply circuit, and outputs a signal by connecting a plurality of nitric oxide sensors in parallel with an amplifying circuit, so that each nitric oxide sensor branch is connected to the The weak current signal is superimposed and then amplified, so that the entire detection device can detect a lower concentration of nitric oxide than a single nitric oxide sensor, so it can be used without using expensive high-precision nitric oxide sensors.
  • the high-precision nitric oxide detection can be realized under the circumstance, and the cost of the high-precision nitric oxide detection instrument is effectively reduced.
  • the present application also provides a nitric oxide concentration detector, which has the above-mentioned effects, which will not be repeated here.
  • FIG. 1 is a schematic structural diagram of a detection device for nitric oxide concentration provided by an embodiment of the application;
  • FIG. 2(a) is a circuit diagram of the first part of a detection device for nitric oxide concentration provided by an embodiment of the present application;
  • FIG. 2(b) is a circuit diagram of the second part of a detection device for nitric oxide concentration provided by an embodiment of the present application;
  • FIG. 2(c) is a circuit diagram of the third part of a detection device for nitric oxide concentration provided by an embodiment of the present application;
  • 101 is a nitric oxide sensor
  • 102 is a power supply circuit
  • 103 is a first amplifying circuit
  • 104 is a second amplifying circuit
  • 105 is a filter circuit.
  • the core of the present application is to provide a nitric oxide concentration detection device and a nitric oxide concentration detector for realizing low-cost and high-precision nitric oxide detection.
  • FIG. 1 is a schematic structural diagram of a device for detecting the concentration of nitric oxide according to an embodiment of the present application.
  • the detection device for nitric oxide concentration includes: a plurality of nitric oxide sensors 101, a power supply circuit 102 and an amplifier circuit;
  • each nitric oxide sensor 101 is connected to the output terminal of the power supply circuit 102, the output terminal of each nitric oxide sensor 101 is connected to the input terminal of the amplifier circuit, and the output terminal of the amplifier circuit is connected to the signal output terminal of the detection device. .
  • the core nitric oxide sensor 101 in medical nitric oxide detectors generally requires an accuracy level of more than 1ppb, and this kind of high-precision sensor is expensive.
  • the weak current of the branch where each nitric oxide sensor 101 is located is superimposed on the main road, and then amplified by the amplifier circuit, so that it can be detected.
  • Even the nitric oxide sensor 101 with an accuracy of less than 1 ppb sold can also achieve the effect of using the medical nitric oxide sensor 101 .
  • the nitric oxide sensor 101 may use an electrochemical nitric oxide sensor 101 .
  • the electrochemical nitric oxide sensor 101 reacts with the nitric oxide in the exhaled breath, outputs a current, and then passes through a plurality of electrochemical nitric oxide sensors 101 The output is superimposed and amplified, and the detection signal is output from the signal output terminal.
  • the amplifying circuit is specifically composed of a first amplifying circuit 103 and a second amplifying circuit 104 .
  • the input end of a first amplifying circuit 103 is connected to the output end of a nitric oxide sensor 101 correspondingly, the output end of each first amplifying circuit 103 is connected with the input end of the second amplifying circuit 104, and the output end of the second amplifying circuit 104 is connected
  • the output terminal is connected with the signal output terminal.
  • the output current of the nitric oxide sensor 101 on the branch is first amplified, so that the current converged on the main road is the superposition of the output current of the amplified nitric oxide sensor 101, and then the amplification is performed on this basis. , so as to achieve higher accuracy.
  • the second amplifying circuit 104 can be formed by using a plurality of operational amplifiers in series.
  • the power supply circuit 102 is specifically constructed based on a voltage stabilizing chip for stabilizing voltage and preventing the circuit from being damaged by pulses.
  • the device for detecting the concentration of nitric oxide may further include a filter circuit 105 disposed between the output end of the amplifying circuit and the signal output end.
  • the amplified current is filtered by the filter circuit 105 to prevent clutter from interfering with the test result.
  • the filter circuit 105 can use the LC filter circuit 105 or the operational amplifier filter circuit 105, which optimizes the filtering effect compared with the passive filter and can amplify the detection signal.
  • the filter circuit 105 may further include a sliding circuit arranged at the output end of the operational amplifier to adjust the signal amplification effect.
  • a capacitor may also be set at the output end of the nitric oxide sensor 101 to filter the alternating current.
  • the nitric oxide concentration detection device provided by the embodiment of the present application can be welded on a circuit board, and packaged with an insulating shell, and the detection position of each nitric oxide sensor 101 and the signal output end of the device can be connected. set externally.
  • Fig. 2(a) is a circuit diagram of a first part of a detection device for nitric oxide concentration provided by an embodiment of the application
  • Fig. 2(b) is a second circuit diagram of a detection device for nitric oxide concentration provided by an embodiment of the application Part of the circuit diagram
  • FIG. 2( c ) is the third part of the circuit diagram of the device for detecting the concentration of nitric oxide provided by the embodiment of the application.
  • the accuracy level of the core nitric oxide sensor 101 in the current medical nitric oxide detector generally requires more than 1ppb, while the common commercially available nitric oxide sensor 101 usually has good accuracy, good stability and specificity.
  • the nitric oxide sensor 101 with an accuracy of 5-20 ppb may not meet the requirements of a nitric oxide detector.
  • a plurality of nitric oxide sensors 101 with an accuracy of 5-20 ppb can be connected in parallel, and the amplification circuit and the signals of each nitric oxide sensor 101 can be superimposed to improve the accuracy and improve the accuracy of the electrochemical sensor. Specificity and stability were not significantly affected. As shown in FIG. 1 , the number of nitric oxide sensors 101 may specifically be three.
  • the embodiments of the present application provide a circuit of a device for detecting the concentration of nitric oxide.
  • the auxiliary electrodes (CE) of each nitric oxide sensor 101 (SN1, SN2, SN3) are respectively connected to the corresponding test points (P5A, P5B, P5C)
  • the reference electrode (RE) is connected to the negative input terminal of the operational amplifier
  • the positive input terminal of the operational amplifier is connected to the DC power supply Vcc.
  • the port J2 is connected to the input power supply, which provides +6V DC voltage for the back-end circuit after voltage division by resistors, and is converted to +2.5V DC voltage by the voltage reference chip U3 (ISL21009BFB125Z can be used)
  • the voltage reference chip U3 ISL21009BFB125Z can be used
  • Different resistance voltage divider circuits are used to provide each DC power supply required by the circuits in Figure 2(a) and Figure 2(b), including the DC power supply Vcc required by the positive input terminals of the operational amplifiers U4A, U5A, and U5B, and the operational amplifier U1A.
  • the DC power supply Vmid required by the positive input terminal of U4B the DC power supply Voff required by the negative input terminals of the operational amplifier U1A and U4B, and the input power supply Vpot1 and Vpot2 of the front end of the operational amplifier U2 and U1B.
  • nitric oxide concentration detector corresponding to the above detection device.
  • the nitric oxide concentration detector provided in the embodiments of the present application may include the nitric oxide concentration detection device provided in any of the above embodiments, and further include an analog-to-digital conversion circuit and a processor;
  • the input end of the analog-to-digital conversion circuit is connected to the signal output end of the detection device, and the output end of the analog-to-digital conversion circuit is connected to the signal input end of the processor.
  • the signal output by the device for detecting the concentration of nitric oxide provided in the above embodiment is an electric signal that has been amplified and filtered, and further signal conversion processing and data transmission processing are required. Therefore, the nitric oxide concentration detector provided by the embodiment of the present application is provided with an analog-to-digital conversion circuit at the signal output end of the nitric oxide concentration detection device to convert the electrical signal output by the nitric oxide concentration detection device into a digital signal, and the input To the processor for storage, calculation, transmission and other operations.
  • the nitric oxide concentration detector provided by the embodiment of the present application may further include a communicator connected to the signal output end of the processor.
  • the communicator can be an RS485 communicator or a wireless communicator such as Wi-Fi and GPRS.
  • a nitric oxide concentration detection device and a nitric oxide concentration detector provided by the present application have been described in detail above.
  • the various embodiments in the specification are described in a progressive manner, and each embodiment focuses on the differences from other embodiments, and the same and similar parts between the various embodiments can be referred to each other. It should be pointed out that for those of ordinary skill in the art, without departing from the principles of the present application, several improvements and modifications can also be made to the present application, and these improvements and modifications also fall within the protection scope of the claims of the present application.

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Abstract

一种一氧化氮浓度检测装置以及一氧化氮浓度检测仪，通过电源电路（102）给一氧化氮传感器（101）供电，通过将多个一氧化氮传感器（101）并联后与放大电路（103,104）连接后输出信号，实现将各一氧化氮传感器（101）支路上的微弱电流信号进行叠加的基础上再放大，从而使整个检测装置相较于单个一氧化氮传感器可以检测到更低浓度的一氧化氮，因而在不采用昂贵的高精度一氧化氮传感器的情况下实现高精度一氧化氮检测，有效降低了成本。

Description

一种一氧化氮浓度的检测装置及一氧化氮浓度检测仪
本申请要求于2020年12月14日提交中国专利局、申请号为202011465293.2、发明名称为“一种一氧化氮浓度的检测装置及一氧化氮浓度检测仪”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。
技术领域
本申请涉及传感器检测电路技术领域，特别是涉及一种一氧化氮浓度的检测装置及一氧化氮浓度检测仪。
背景技术
一氧化氮传感器用于测量一氧化氮浓度，广泛应用于各个领域。例如，一氧化氮作为一种新型的无创、便于检测的生物标记物，可以用于诊断气道炎性疾病。呼出气中一氧化氮的浓度变化能够反映哮喘的发生、病情变化以及哮喘表型，通过一氧化氮检测仪器检测呼出气中一氧化氮的浓度，有助于对哮喘的诊断和治疗，还可以评估治疗的疗效。由于呼出的一氧化氮浓度较低，通常为十亿分之一(part per billion，ppb)级别的，对检测仪器的灵敏度要求比较高，而高精度的一氧化氮传感器价格昂贵，由此带来了检测费用高的一系列问题。
如何降低高精度一氧化氮检测仪的成本，是本领域技术人员需要解决的技术问题。
发明内容
本申请的目的是提供一种一氧化氮浓度的检测装置及一氧化氮浓度检测仪，用于实现低成本高精度的一氧化氮检测。
为解决上述技术问题，本申请提供一种一氧化氮浓度的检测装置，包括：多个一氧化氮传感器，电源电路和放大电路；
其中，各所述一氧化氮传感器的供电端与所述电源电路的输出端连接，所述各所述一氧化氮传感器的输出端与所述放大电路的输入端连接，所述 放大电路的输出端与检测装置的信号输出端连接。
可选的，所述一氧化氮传感器的数量具体为三个。
可选的，所述放大电路具体包括第一放大电路和第二放大电路；
其中，一个所述第一放大电路的输入端与一个所述一氧化氮传感器的输出端对应连接，各所述第一放大电路的输出端与所述第二放大电路的输入端连接，所述第二放大电路的输出端与所述信号输出端连接。
可选的，所述一氧化氮传感器具体为精度为5-20ppb的一氧化氮传感器。
可选的，所述一氧化氮传感器具体为电化学一氧化氮传感器。
可选的，还包括设于所述放大电路的输出端与所述信号输出端之间的滤波电路。
可选的，所述电源电路具体基于稳压芯片搭建而成。
为解决上述技术问题，本申请还提供一种一氧化氮浓度检测仪，包括上述任意一项所述的一氧化氮浓度的检测装置，还包括模数转换电路和处理器；
其中，所述模数转换电路的输入端与所述检测装置的信号输出端连接，所述模数转换电路的输出端与所述处理器的信号输入端连接。
可选的，还包括与所述处理器的信号输出端连接的通信器。
可选的，所述通信器具体为RS485通信器。
本申请所提供的一氧化氮浓度的检测装置，通过电源电路给一氧化氮传感器供电，通过将多个一氧化氮传感器并联后与放大电路连接后输出信号，实现将各一氧化氮传感器支路上的微弱电流信号进行叠加的基础上再放大，从而使整个检测装置相较于单个一氧化氮传感器可以检测到更低浓度的一氧化氮，因而可以在不采用昂贵的高精度一氧化氮传感器的情况下实现高精度的一氧化氮检测，有效降低了高精度一氧化氮检测仪器的成本。
本申请还提供一种一氧化氮浓度检测仪，具有上述效果，在此不再赘述。
附图说明
为了更清楚的说明本申请实施例或现有技术的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单的介绍，显而易见地，下面描述中的附图仅仅是本申请的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1为本申请实施例提供的一种一氧化氮浓度的检测装置的结构示意图；
图2(a)为本申请实施例提供的一种一氧化氮浓度的检测装置的第一部分电路图；
图2(b)为本申请实施例提供的一种一氧化氮浓度的检测装置的第二部分电路图；
图2(c)为本申请实施例提供的一种一氧化氮浓度的检测装置的第三部分电路图；
其中，101为一氧化氮传感器，102为电源电路，103为第一放大电路，104为第二放大电路，105为滤波电路。
具体实施方式
本申请的核心是提供一种一氧化氮浓度的检测装置及一氧化氮浓度检测仪，用于实现低成本高精度的一氧化氮检测。
下面将结合本申请实施例中的附图，对本申请实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本申请一部分实施例，而不是全部的实施例。基于本申请中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本申请保护的范围。
图1为本申请实施例提供的一种一氧化氮浓度的检测装置的结构示意图。
如图1所示，本申请实施例提供的一氧化氮浓度的检测装置包括：多 个一氧化氮传感器101，电源电路102和放大电路；
其中，各一氧化氮传感器101的供电端与电源电路102的输出端连接，各一氧化氮传感器101的输出端与放大电路的输入端连接，放大电路的输出端与检测装置的信号输出端连接。
目前医用的一氧化氮检测仪中核心的一氧化氮传感器101精度等级要求一般1ppb以上，这种高精度传感器价格昂贵。而本申请实施例通过将多个一氧化氮传感器101并联，各一氧化氮传感器101所在支路的微弱电流在干路上叠加，再经过放大电路进行放大，从而能够被检测到，因而即使采用市售的精度未达到1ppb的一氧化氮传感器101，也能够达到采用医用一氧化氮传感器101的效果。
在具体实施中，一氧化氮传感器101可以采用电化学一氧化氮传感器101。稳定流速的呼出气一氧化氮流经电化学一氧化氮传感器101时，电化学一氧化氮传感器101与呼出气中的一氧化氮反应，输出电流，进而通过多个电化学一氧化氮传感器101的输出进行叠加、放大，从信号输出端输出检测信号。
为进一步提高检测精度，如图1所示，放大电路具体由第一放大电路103和第二放大电路104组成。其中，一个第一放大电路103的输入端与一个一氧化氮传感器101的输出端对应连接，各第一放大电路103的输出端与第二放大电路104的输入端连接，第二放大电路104的输出端与信号输出端连接。通过第一放大电路103，先对支路上一氧化氮传感器101的输出电流进行放大，从而汇聚在干路上的电流是放大后的一氧化氮传感器101输出电流的叠加，在此基础上再进行放大，从而达到更高精度的效果。根据实际需要，第二放大电路104可以采用多个运算放大器串联而成。
为提高检测信号的质量，电源电路102具体基于稳压芯片搭建而成，用以稳压以及避免电路受脉冲破坏。
如图1所示，本申请实施例提供的一氧化氮浓度的检测装置还可以包括设于放大电路的输出端与信号输出端之间的滤波电路105。通过滤波电路105对放大后的电流进行滤波，避免杂波干扰测试结果。滤波电路105可以采用LC滤波电路105，也可以运算放大器滤波电路105，后者相较于 无源滤波器优化了滤波效果，且可以对检测信号进行放大。滤波电路105还可以包括设于运算放大器输出端的滑动电路，用以调节信号放大效果。
此外，在各一氧化氮传感器101所在支路，在一氧化氮传感器101的输出端还可以设置电容，用以滤除交流电。
在实际应用中，可以将本申请实施例提供的一氧化氮浓度的检测装置焊接于一电路板上，并采用绝缘外壳进行封装，将各一氧化氮传感器101的检测位置和装置的信号输出端设置于外部。
本申请实施例提供的
图2(a)为本申请实施例提供的一种一氧化氮浓度的检测装置的第一部分电路图；图2(b)为本申请实施例提供的一种一氧化氮浓度的检测装置的第二部分电路图；图2(c)为本申请实施例提供的一种一氧化氮浓度的检测装置的第三部分电路图。
在实际应用中，由于目前医用的一氧化氮检测仪中核心的一氧化氮传感器101精度等级要求一般1ppb以上，而市售常见的一氧化氮传感器101通常为精度为稳定性好、专一性好的5-20ppb的阿尔法一氧化氮传感器101。人体呼出气一氧化氮浓度检测呼吸道炎症指标：儿童：正常<20ppb，轻度20-35ppb，高度>35ppb；成人：正常<25ppb，轻度25-50ppb，重度>50ppb，所以一氧化氮检测仪的精度起码要达到1ppb，而精度为5-20ppb的一氧化氮传感器101可能达不到一氧化氮检测仪的要求。因此，在本申请实施例中可以将多个精度为5-20ppb的一氧化氮传感器101并联，通过放大电路以及各一氧化氮传感器101的信号叠加，实现精度的提高，且对电化学传感器的专一性和稳定性没有明显的影响。如图1所示，一氧化氮传感器101的数量具体可以为三个。
基于此，为便于实际应用，本申请实施例提供一种一氧化氮浓度的检测装置的电路。如图2(a)、图2(b)所示，其中，各一氧化氮传感器101(SN1、SN2、SN3)的辅助电极(CE)分别与对应的测试点(P5A、P5B、P5C)连接，参比电极(RE)连接运算放大器的负极输入端，运算放大器的正极输入端连接直流电源Vcc。三个一氧化氮传感器101(SN1、SN2、 SN3)的工作电极WEI联结在一起后经过由两级运算放大器U4B和U2搭建的放大电路，连接输出端口JI以及输出管脚O/P1；三个一氧化氮传感器101(SN1、SN2、SN3)的工作电极WE2联结在一起后经过由两级运算放大器U1A和U1B搭建的放大滤波电路105，连接输出端口J3以及输出管脚O/P2；其中，运算放大器U4B、U2、U1A均采用LT6011，运算放大器U1B采用TLV2211；运算放大器U1A的输出端分别运算放大器U4B的负极输入端和测试点P6。
如图2(c)所示，端口J2连接输入电源，通过电阻分压后为后端电路提供+6V直流电压，通过由电压基准芯片U3(可以采用ISL21009BFB125Z)转换为+2.5V直流电压后，以不同的电阻分压电路提供图2(a)和图2(b)中电路所需的各直流电源，包括运算放大器U4A、U5A、U5B的正极输入端所需的直流电源Vcc，运算放大器U1A、U4B的正极输入端所需的直流电源Vmid，运算放大器U1A、U4B的负极输入端所需的直流电源Voff，运算放大器U2、U1B前端的输入电源Vpot1和Vpot2。
上文详述了一氧化氮浓度的检测装置对应的各个实施例，在此基础上，本申请还公开了与上述检测装置对应的一氧化氮浓度检测仪。
本申请实施例提供的一氧化氮浓度检测仪可以包括上述任一实施例提供的一氧化氮浓度的检测装置，还包括模数转换电路和处理器；
其中，模数转换电路的输入端与检测装置的信号输出端连接，模数转换电路的输出端与处理器的信号输入端连接。
上述实施例中提供的一氧化氮浓度的检测装置输出的信号为经过放大滤波的电信号，需要进一步进行信号转化处理和数据传输处理。故本申请实施例提供的一氧化氮浓度检测仪在一氧化氮浓度的检测装置的信号输出端设置模数转换电路用以将一氧化氮浓度的检测装置输出的电信号转化为数字信号，输入至处理器中进行存储、计算、传输等操作。
在此基础上，本申请实施例提供的一氧化氮浓度检测仪还可以包括与处理器的信号输出端连接的通信器。该通信器可以采用RS485通信器，也 可以采用Wi-Fi、GPRS等无线通信器。
以上对本申请所提供的一种一氧化氮浓度的检测装置及一氧化氮浓度检测仪进行了详细介绍。说明书中各个实施例采用递进的方式描述，每个实施例重点说明的都是与其他实施例的不同之处，各个实施例之间相同相似部分互相参见即可。应当指出，对于本技术领域的普通技术人员来说，在不脱离本申请原理的前提下，还可以对本申请进行若干改进和修饰，这些改进和修饰也落入本申请权利要求的保护范围内。
还需要说明的是，在本说明书中，诸如第一和第二等之类的关系术语仅仅用来将一个实体或者操作与另一个实体或操作区分开来，而不一定要求或者暗示这些实体或操作之间存在任何这种实际的关系或者顺序。而且，术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含，从而使得包括一系列要素的过程、方法、物品或者设备不仅包括那些要素，而且还包括没有明确列出的其他要素，或者是还包括为这种过程、方法、物品或者设备所固有的要素。在没有更多限制的情况下，由语句“包括一个……”限定的要素，并不排除在包括所述要素的过程、方法、物品或者设备中还存在另外的相同要素。

Claims (10)

  1. 一种一氧化氮浓度的检测装置，其特征在于，包括：多个一氧化氮传感器，电源电路和放大电路；
    其中，各所述一氧化氮传感器的供电端与所述电源电路的输出端连接，所述各所述一氧化氮传感器的输出端与所述放大电路的输入端连接，所述放大电路的输出端与检测装置的信号输出端连接。
  2. 根据权利要求1所述的检测装置，其特征在于，所述一氧化氮传感器的数量具体为三个。
  3. 根据权利要求1所述的检测装置，其特征在于，所述放大电路具体包括第一放大电路和第二放大电路；
    其中，一个所述第一放大电路的输入端与一个所述一氧化氮传感器的输出端对应连接，各所述第一放大电路的输出端与所述第二放大电路的输入端连接，所述第二放大电路的输出端与所述信号输出端连接。
  4. 根据权利要求1所述的检测装置，其特征在于，所述一氧化氮传感器具体为精度为5-20ppb的一氧化氮传感器。
  5. 根据权利要求1所述的检测装置，其特征在于，所述一氧化氮传感器具体为电化学一氧化氮传感器。
  6. 根据权利要求1所述的检测装置，其特征在于，还包括设于所述放大电路的输出端与所述信号输出端之间的滤波电路。
  7. 根据权利要求1所述的检测装置，其特征在于，所述电源电路具体基于稳压芯片搭建而成。
  8. 一种一氧化氮浓度检测仪，其特征在于，包括权利要求1至7任意一项所述的一氧化氮浓度的检测装置，还包括模数转换电路和处理器；
    其中，所述模数转换电路的输入端与所述检测装置的信号输出端连接，所述模数转换电路的输出端与所述处理器的信号输入端连接。
  9. 根据权利要求8所述的一氧化氮浓度检测仪，其特征在于，还包括与所述处理器的信号输出端连接的通信器。
  10. 根据权利要求9所述的一氧化氮浓度检测仪，其特征在于，所述通信器具体为RS485通信器。
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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008292307A (ja) * 2007-05-24 2008-12-04 Denso Corp ガス濃度検出装置
CN102353855A (zh) * 2011-09-28 2012-02-15 上海安平静电科技有限公司 一种便携式静电检测装置及其静电检测方法
CN103278229A (zh) * 2013-05-20 2013-09-04 天利航空科技深圳有限公司 直升飞机称重测量器及直升飞机重心测量方法
CN104407026A (zh) * 2014-11-28 2015-03-11 无锡市尚沃医疗电子股份有限公司 一口气多参数呼气一氧化氮测量方法和装置
CN104720830A (zh) * 2014-12-10 2015-06-24 微昔智能科技(上海)有限公司 女性盆底肌压力检测装置
WO2017171419A1 (ko) * 2016-03-30 2017-10-05 주식회사 코멧네트워크 질소산화물 농도 측정 및 암모니아 슬립 감지 센서
CN107328494A (zh) * 2017-06-26 2017-11-07 华中科技大学 一种微弹体纳米压力传感器及健康监测系统
CN109813780A (zh) * 2019-02-01 2019-05-28 荆州市爱尔瑞科技有限公司 一种电化学一氧化氮气体传感器
CN111374668A (zh) * 2020-04-14 2020-07-07 合肥微谷医疗科技有限公司 一种家用呼出气检测仪及其使用方法

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008292307A (ja) * 2007-05-24 2008-12-04 Denso Corp ガス濃度検出装置
CN102353855A (zh) * 2011-09-28 2012-02-15 上海安平静电科技有限公司 一种便携式静电检测装置及其静电检测方法
CN103278229A (zh) * 2013-05-20 2013-09-04 天利航空科技深圳有限公司 直升飞机称重测量器及直升飞机重心测量方法
CN104407026A (zh) * 2014-11-28 2015-03-11 无锡市尚沃医疗电子股份有限公司 一口气多参数呼气一氧化氮测量方法和装置
CN104720830A (zh) * 2014-12-10 2015-06-24 微昔智能科技(上海)有限公司 女性盆底肌压力检测装置
WO2017171419A1 (ko) * 2016-03-30 2017-10-05 주식회사 코멧네트워크 질소산화물 농도 측정 및 암모니아 슬립 감지 센서
CN107328494A (zh) * 2017-06-26 2017-11-07 华中科技大学 一种微弹体纳米压力传感器及健康监测系统
CN109813780A (zh) * 2019-02-01 2019-05-28 荆州市爱尔瑞科技有限公司 一种电化学一氧化氮气体传感器
CN111374668A (zh) * 2020-04-14 2020-07-07 合肥微谷医疗科技有限公司 一种家用呼出气检测仪及其使用方法

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