WO2022124140A1 - 美容機器及びそれを用いた美容方法 - Google Patents

美容機器及びそれを用いた美容方法 Download PDF

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Publication number
WO2022124140A1
WO2022124140A1 PCT/JP2021/043870 JP2021043870W WO2022124140A1 WO 2022124140 A1 WO2022124140 A1 WO 2022124140A1 JP 2021043870 W JP2021043870 W JP 2021043870W WO 2022124140 A1 WO2022124140 A1 WO 2022124140A1
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WO
WIPO (PCT)
Prior art keywords
skin
beauty device
beauty
electrode
hollow housing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2021/043870
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English (en)
French (fr)
Japanese (ja)
Inventor
デイヴィッド ディアズ オーディナリオ
和之 宮沢
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shiseido Co Ltd
Original Assignee
Shiseido Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiseido Co Ltd filed Critical Shiseido Co Ltd
Priority to CN202180076189.0A priority Critical patent/CN116547034A/zh
Priority to JP2022568206A priority patent/JPWO2022124140A1/ja
Publication of WO2022124140A1 publication Critical patent/WO2022124140A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation

Definitions

  • the present invention relates to a beauty device, preferably a wearable beauty device.
  • the present invention also relates to a cosmetological method characterized by enabling collagen production, moisturizing, and wrinkle reduction of the skin using a cosmetological device.
  • An object of the present invention is to provide a beauty device that can be worn hands-free and that can be worn inconspicuously and can go out, and a beauty method using the same.
  • the present invention includes the following inventions.
  • Skin electrodes that come into contact with the user's skin and give electrical stimulation, A stimulus generator that generates electrical stimuli, A hollow housing that houses the stimulus generation unit, the control unit, and a power source that supplies electric power to the stimulus generation unit and the control unit.
  • the ground electrode provided on the outer surface of the hollow housing and A beauty device including a conductive portion that conducts the skin electrode and the stimulus generating portion and transmits the electrical stimulus generated in the stimulating portion to the skin electrode.
  • the beauty device according to (1).
  • the beauty device according to (2) further comprising an engaging portion for engaging with the user's ear and attaching the hollow housing to the ear.
  • the hollow housing has a bow-shaped inner peripheral wall, a bow-shaped outer peripheral wall having a radius of curvature larger than that of the inner peripheral wall, and a pair of side walls extending in parallel between the inner peripheral wall and the outer peripheral wall. And end walls joined to both ends of the inner peripheral wall, the outer peripheral wall and the pair of side walls.
  • the cosmetological device according to (3) wherein the inner peripheral wall forms the engaging portion and engages with the base of the user's ear on the inner peripheral wall.
  • the conductive portion includes a conductive wire connecting the stimulus generating portion and the skin electrode, and the conductive wire is attached to the hollow housing from one end on the upper side of the hollow housing when the beauty device is attached.
  • the beauty device according to (4) which was introduced inside.
  • the beauty device according to (5) wherein the ground electrode is arranged along the outer surface of the inner peripheral wall of the hollow housing.
  • the hollow housing extends from one end to the other end and has a groove that opens on one side surface of the hollow housing, and the groove is formed in the earlobe of the user when the beauty device is attached.
  • the beauty device according to (3) which forms an engaging portion that engages with the outer peripheral portion of the housing.
  • the beauty device according to (7) wherein the ground electrode is arranged along the bottom of the groove.
  • a curved extension portion coupled to one end of the hollow housing is further provided, and the extension portion engages with the base of the user's ear when the beauty device is attached.
  • the conductive portion includes a conductive wire connecting the stimulus generating portion and the skin electrode.
  • the beauty device according to (9), wherein the extension portion is formed of a hollow member, and the conductive wire is extended in the extension portion.
  • a curved extension portion coupled to one end of the hollow housing is further provided, and when the beauty device is attached, the extension portion forms an engagement portion that engages with the base of the user's ear.
  • the beauty device according to (1) The beauty device according to (1).
  • the conductive portion includes a conductive wire connecting the stimulus generating portion and the skin electrode.
  • the conductive portion includes a conductive wire connecting the stimulus generating portion and the skin electrode.
  • the hollow housing has first and second arms, the first and second arms being connected to each other at one end of each, and the first and second arms.
  • the cosmetological apparatus according to (1) wherein the conductive wire is introduced into the hollow housing from an end opposite to the connected end.
  • the adhesive layer attached to one side surface of the base layer and having adhesiveness to the user's skin, and the base layer and the adhesive layer.
  • the adhesive layer contains a drug.
  • the cosmetic device according to any one of (1) to (19) is applied hands-free to the target skin.
  • the cosmetological method according to (20), wherein the improvement of the skin condition of the subject is promotion of collagen production of the subject's skin and / or continuous moisturization.
  • the beauty device of the present invention preferably the wearable beauty device, is inconspicuous to wear, and is not limited to use in a specific place, and can be worn while working or going out. Furthermore, when an alternating current having a predetermined current value and frequency is applied, collagen production is promoted, and moisturizing and wrinkle improvement are also possible.
  • FIG. 3 is a plan view of the beauty device of FIG. 8 as viewed from above.
  • FIG. 3 is a perspective view of the beauty device of FIG. 8 as viewed from another direction. It is a perspective view of the beauty apparatus according to 3rd Embodiment.
  • FIG. 11 is a plan view of the beauty device of FIG. 11 as viewed from above. It is a perspective view of the beauty apparatus according to 4th Embodiment.
  • FIG. 3 is a perspective view of the beauty device of FIG. 13 as viewed from another direction. It is a perspective view of the beauty apparatus according to 5th Embodiment.
  • FIG. 3 is a perspective view of the beauty device of FIG. 15 as viewed from another direction. It is a perspective view of the beauty apparatus according to 6th Embodiment. It is a perspective view which looked at the beauty device of FIG. 17 from another direction.
  • FIG. shows the collagen amount (ng / cell) in Example 1.
  • FIG. It is a figure which shows the change (au) of the water content of the skin in Example 2.
  • FIG. It is a figure which shows the change of the wrinkle in Example 2.
  • FIG. The figure below is an actual photograph of the skin taken with an ANTERA 3D camera, and the figure above is an image of the surface morphology of the skin portion corresponding to the figure below.
  • FIG. Shows the effect of reducing wrinkles on facial facial devices from other companies on the market. The comparison test result between the apparatus of this invention and the product of another company is shown.
  • the present invention relates to a beauty device, preferably a wearable beauty device. Since the beauty device of the present invention, preferably a wearable beauty device, can be used hands-free, it can be worn while working. It can be used in various situations such as work, commuting, and wearing while shopping. Further, the beauty device of the present invention, preferably a wearable beauty device, is small and light, so that it is easy to carry.
  • the beauty device 1 includes a device main body 10 and a sheet electrode 50. As shown in FIG. 1, the beauty device 1 detachably attaches a sheet electrode 50 forming a skin electrode to the surface of the user's skin S, and the conductor 60 as a conductive portion allows the apparatus main body 10 and the sheet electrode to be attached to the surface. It is designed to be used by electrically connecting to 50. That is, the beauty device 1 constitutes a beauty device used by being attached to the surface of the skin S of the human body, particularly the human face.
  • the apparatus main body 10 includes an oscillator that generates an alternating current as a stimulus generating unit for applying an electrical stimulus to the skin to which the sheet electrode 50 is attached, and a control unit for controlling the oscillator. It has a hollow housing for accommodating the constituent circuit board 24. The control unit controls the amount of current, frequency, waveform, amplitude, etc. of the current generation unit.
  • a battery 26 is further housed as a power source for supplying electric power to the oscillator and the control unit.
  • the battery 26 can be a rechargeable rechargeable battery.
  • the housing of the apparatus main body 10 is parallel between the bow-shaped inner peripheral wall 12 as an engaging portion, the bow-shaped outer peripheral wall 14 having a larger radius of curvature than the inner peripheral wall 12, and the inner peripheral wall 12 and the outer peripheral wall 14. It is formed of a pair of side walls 16 and 18 extending to the inner peripheral wall, an outer peripheral wall 12 and 14, and end walls 20 and 22 connected to both ends of the pair of side walls 16 and 18.
  • the housings 12, 14, 16 and 18 are generally arcuate housings that can be worn on one of the user's ears.
  • the device body 10 is arranged between the back surface of the user's ear and the temporal region so that the inner peripheral wall 12 contacts the back surface of the ear and one of the side walls 16 and 18 contacts the temporal region during wearing. To.
  • the apparatus main body 10 also has a switch 28 for turning on / off the oscillator main body 10, particularly the oscillator on the circuit board 24.
  • the switch 28 partially protrudes from the outer peripheral wall 14 of the housing, and is pushed in the radial direction to be turned on and off.
  • the position and shape of the switch 28 are not limited, and any switch 28 can be used.
  • a wireless communication port (not shown) is provided instead of the switch 28, and the control unit is remotely operated wirelessly by, for example, an operating device 70 that uses data stored in a cloud or the like. You may.
  • the circuit board 24 may include a wireless communication port capable of wireless communication with an external operating device 70. Based on the signal from the operating device 70, the control unit can control the current generated by the transmitter, particularly its frequency and voltage.
  • the operating device 70 can be formed by a dedicated wireless operating device (not shown). In this case, the operating device 70 can be wirelessly connected to the wireless communication port by analog or digital communication of a specific frequency.
  • the operating device 70 may be a commercially available handheld device such as a smartphone or tablet.
  • the operation application can be installed on the handheld device, and the operation device 70 can be wirelessly connected to the wireless communication port via WiFi or Bluetooth (registered trademark).
  • the circuit board 24 can be provided with a charging terminal for connecting a charger (not shown) for charging the battery 26.
  • This terminal allows the cord of the charger (not shown) to be connected through one of the end walls, particularly the small holes 20a and 20b formed in the end wall 20 arranged on the lower side at the time of mounting.
  • the charging terminal is a separate type in which the positive pole and the negative pole are separated, but it may be a coaxial type charging terminal having a positive pole and a negative pole.
  • the charging terminal may be a terminal for connecting a Type-A or Type-C USB cable, a Lightning (registered trademark) cable, or the like.
  • the apparatus main body 10 includes first and second electrodes 30 and 32.
  • the first electrode 30 is provided along the inner peripheral wall 12 so as to be exposed to the outside of the housing, and the second electrode 32 is adjacent to the end wall 22 arranged on the upper side in the housing at the time of mounting. It is accessible from the outside through the port hole 22a formed in the end wall 22.
  • the sheet electrode 50 is made of a conductive material that applies a current from an oscillator to the skin S.
  • the conductive material is optional, such as a conductive polymer having flexibility so as to be able to follow the unevenness of the skin, carbon black, resin, dielectric elastomer actuator (DEA), IPMC actuator, PVC gel, etc., and AC current is used.
  • DEA dielectric elastomer actuator
  • IPMC actuator IPMC actuator
  • PVC gel etc.
  • AC current AC current is used.
  • the sheet electrode 50 can take any shape. It may have a shape that matches the shape of the eyelid portion as shown in FIG. 1, or may have a shape that matches the shape of a desired sticking portion such as the cheek.
  • the sheet electrode 50 may be thin so that it can be attached to the user's skin, and may be transparent so that the wearing is not conspicuous, or may be an embodiment that matches the color of the user's skin.
  • the sheet electrode 50 may be used repeatedly or may be disposable, and it may be possible to apply make-up or a sunscreen agent on the sheet electrode.
  • the sheet electrode 50 itself may have adhesiveness, and the sheet electrode 50 is attached to the user's skin S within a range in which an alternating current having the frequency and current of the present invention can reach the skin.
  • the adhesive layer may be provided.
  • the conductor 60 has an elongated conductor main body portion 62 and a connector portion 64 provided at one end of the conductor main body portion 62.
  • the opposite end of the conductor body 62 can be coupled to the sheet electrode 50 using a well-known coupling technique such as thermocompression bonding that applies heat and pressure.
  • the connector portion 64 includes a plate 64a bonded to the conductor 60. By inserting the connector portion 64 into the port hole 22a formed in the end wall 22, the connector portion 64 comes into contact with the second electrode 32. In this way, the sheet electrode 50 is electrically connected to the second electrode 32 via the conductor 60.
  • the sheet electrode 50 is attached to a desired position of the user's skin S, particularly the skin S of the face, for example, near the outer corner of the eye, and the device main body 10 is attached to the ear near the attached sheet electrode 50.
  • the end wall 22 adjacent to the second electrode 32 is brought close to the target skin, for example, the skin near the outer corner of the user's eye.
  • the device main body 10 can be attached to the user's ear with the end wall 22 facing upward.
  • the first electrode 30 comes into contact with the back surface of the user's ear, and the first electrode 30 and the user are electrically connected.
  • the connector portion 64 of the conductor 60 into the port hole 22a of the apparatus main body 10 the user is electrically connected via the conductor 60 and the sheet electrode 50.
  • a current is applied to the skin S of the user by turning on the switch 28 or by operating the wireless operation device 70 to turn on the device main body 10.
  • the applied current is an alternating current, and as an example, it can be a pulsed current as shown in FIG.
  • the current waveform shown in FIG. 6 is an example, and the present invention is not limited to this, and a square wave, a sine wave, a triangular wave, a sawtooth wave, or the like can be arbitrarily set.
  • the frequency and voltage output from the device main body 10 can be changed by the wireless operation device 70.
  • the beauty device 1 when the beauty device 1 is attached to the user's skin S, the first electrode 30 and the sheet electrode 50 come into contact with the user's skin S, and an alternating current is generated from the oscillator by operating the apparatus main body 10.
  • the first electrode 30 and the sheet electrode 50 are electrically conducted through the user's skin S, and an AC current is applied to the user's skin S.
  • an alternating current when an alternating current is applied by the beauty device 1, collagen production is promoted in the skin S in contact with the first portion 50a of the sheet electrode 50, which is a mounting site, moisturizing is promoted, and wrinkles are formed. It will be improved.
  • the beauty device 100 includes a device main body 110 and a sheet electrode 130 similar to the sheet electrode 50 according to the first embodiment.
  • the sheet electrode 130 forming the skin electrode is detachably attached to the surface of the user's skin S as in the first embodiment, and the device main body 110 and the sheet electrode are attached by the conductor as the conductive portion. It is designed to be used by electrically connecting it to the 130. That is, the beauty device 100 constitutes a beauty device used by being attached to the surface of the skin S of the human body, particularly the human face.
  • the device body 110 has at least a hollow housing 112 that houses an oscillator, a control unit, and a battery, similar to the housing of the first embodiment.
  • the housing 112 is generally arched or arcuate and has a groove 114.
  • the groove 114 extends from one end 112a of the housing 112 to the other end 112b and is open to the inner peripheral side surface 112c of the bow-shaped or arc-shaped housing 112.
  • the groove 114 forms an engaging portion that engages with the outer peripheral portion of the user's earlobe when the beauty device 100 is attached.
  • the ground electrode 118 extends along the bottom portion or the bottom surface 114a of the groove portion 114.
  • the beauty device 100 includes an extension portion 120 extending between the device main body 110 and the sheet electrode 130.
  • the extension 120 is coupled to the housing 112 at one end thereof.
  • the extension portion 120 has at least a predetermined length portion 122 curved from one end coupled to the housing 112. When the beauty device 100 is attached, the curved portion 122 engages with the base of the user's ear so that the beauty device 100, particularly the device 10, can be attached to the user's ear more stably.
  • the apparatus main body 110 also has a switch 116 for turning on / off the oscillator housed in the beauty device 100, particularly the housing 112.
  • the switch 116 is provided on the outer peripheral side surface 112d of the housing 112, which is opposite to the inner peripheral side surface 112c where the groove 114 is open. It is designed to be turned on and off by touching the switch 116.
  • the position and shape of the switch 116 are not limited, and any one can be used, and the control unit is wirelessly operated remotely by a wireless operation device similar to the wireless operation device 70 of the first embodiment instead of the switch 116. It may be a thing.
  • the sheet electrode 130 is attached to the end portion of the extension portion 120 opposite to the apparatus main body 110.
  • the extension portion 120 can be formed of a hollow member, and a conductive wire as a conductive portion is extended therein.
  • the sheet electrode 130 has the same configuration, operation, and effect as the sheet electrode 50 of the first embodiment, and detailed description thereof will be omitted.
  • the beauty device 200 according to the third embodiment includes a device main body 210 and a sheet electrode 230 similar to the sheet electrode 50 according to the first embodiment.
  • the sheet electrode 230 forming the skin electrode is detachably attached to the surface of the user's skin S, and the apparatus main body 210 and the sheet are formed by the conductor as the conductive portion. It is designed to be used by electrically connecting it to the electrode 230. That is, the beauty device 200 constitutes a beauty device used by being attached to the surface of the skin S of the human body, particularly the human face.
  • the device main body 210 has at least a hollow housing 212 that houses an oscillator, a control unit, and a battery, similar to the housing of the first embodiment.
  • the housing 212 has a substantially disk shape and has first and second side surfaces 212a and 212b.
  • a ground electrode is arranged on the second side surface 212b which comes into contact with the skin surface of the wearer on the side opposite to the first side surface 212a which is the front side at the time of wearing.
  • the beauty device 200 includes an extension portion 220 extending between the device main body 210 and the sheet electrode 230.
  • the extension 220 is coupled to the housing 212 at one end thereof.
  • the extension 220 has at least a predetermined length portion 222 curved from one end coupled to the housing 212. When the beauty device 200 is attached, the curved portion 222 forms an engaging portion that engages with the base of the user's ear.
  • the device main body 210 also has a switch for turning on / off the oscillator housed in the beauty device 200, particularly the housing 212.
  • the switch is formed by a first side surface 212a.
  • the switch 116 is touched or pushed in a direction perpendicular to the first side surface 212a to perform an on / off operation.
  • the position and shape of the switch are not limited, and any switch can be used.
  • the control unit is wirelessly operated remotely by a wireless operation device similar to the wireless operation device 70 of the first embodiment. There may be.
  • the sheet electrode 230 is attached to the end of the extension 220 on the opposite side of the device main body 210.
  • the extension portion 220 can be formed of a hollow member, and a conductive wire as a conductive portion is extended therein.
  • the sheet electrode 230 has the same configuration, operation, and effect as the sheet electrode 50 of the first embodiment, and detailed description thereof will be omitted.
  • the beauty device 300 according to the fourth embodiment includes a device main body 310 and a sheet electrode 330 similar to the sheet electrode 50 according to the first embodiment. Similar to the first embodiment, the beauty device 300 detachably attaches the sheet electrode 330 forming the skin electrode to the surface of the user's skin S, and the device main body 310 and the sheet are provided by the conductor as the conductive portion. It is designed to be used by electrically connecting it to the electrode 330. That is, the beauty device 300 constitutes a beauty device used by being attached to the surface of the skin S of the human body, particularly the human face.
  • the device main body 310 has at least a hollow housing 312 that houses an oscillator, a control unit, and a battery, similar to the housing of the first embodiment.
  • the housing 312 is a generally bow-shaped housing that can be worn on one of the user's ears.
  • the apparatus main body 310 is mounted so that the inner peripheral wall 312a as an engaging portion of the housing 312 comes into contact with the back surface of the wearer's ear, and the ground electrode is arranged on the inner peripheral wall 312a.
  • the beauty device 300 includes an extension portion 320 extending between the device main body 310 and the sheet electrode 330.
  • the extension 320 is coupled to the housing 312 at one end thereof.
  • the extension portion 320 can be formed of a hollow member.
  • the device body 310 also has a switch 316 that turns the beauty device 300, in particular the oscillator housed in the housing 312, on and off.
  • the switch 316 is arranged on a bow-shaped outer wall 312b having a radius of curvature larger than that of the inner wall 312a.
  • the switch 316 is touched or pushed in to turn it on and off.
  • the position and shape of the switch 316 are not limited, and any one can be used, and the control unit is wirelessly operated remotely by a wireless operation device similar to the wireless operation device 70 of the first embodiment instead of the switch 316. It may be a thing.
  • the sheet electrode 330 is attached to the end of the extension 320 on the opposite side of the device main body 310.
  • a conductive wire as a conductive portion is extended inside the extension portion 320.
  • the sheet electrode 330 has the same configuration, operation, and effect as the sheet electrode 50 of the first embodiment, and detailed description thereof will be omitted.
  • the beauty device 400 according to the fifth embodiment includes a device main body 410 and a sheet electrode 430 similar to the sheet electrode 50 according to the first embodiment. Similar to the first embodiment, the beauty device 400 detachably attaches the sheet electrode 430 forming the skin electrode to the surface of the user's skin S, and the device main body 410 and the sheet are provided by the conductor as the conductive portion. It is designed to be used by electrically connecting it to the electrode 430. That is, the beauty device 400 constitutes a beauty device used by being attached to the surface of the skin S of the human body, particularly the human face.
  • the device main body 410 has at least a hollow housing 412 that houses an oscillator, a control unit, and a battery, similar to the housing of the first embodiment.
  • the housing 412 is a generally arched or arcuate housing that can be worn on one of the user's ears.
  • the apparatus main body 410 is mounted so that the inner peripheral wall 412a as an engaging portion of the housing 412 is in contact with the back surface of the wearer's ear, and the ground electrode is arranged on the inner peripheral wall 412a.
  • the beauty device 400 includes an extension portion 420 extending between the device main body 410 and the sheet electrode 430.
  • the extension 420 is coupled to the housing 412 at one end thereof.
  • the extension portion 420 can be formed of a hollow member.
  • the apparatus main body 410 also has a switch 416 for turning on / off the oscillator 400 housed in the beauty device 400, particularly the housing 412.
  • the switch 416 is arranged on the side surface of the bulging portion 414 protruding radially outward from the outer peripheral wall 412b of the housing 412.
  • the switch 416 is touched or pushed in to turn it on and off.
  • the position and shape of the switch 416 are not limited, and any one can be used, and the control unit is wirelessly operated remotely by a wireless operation device similar to the wireless operation device 70 of the first embodiment instead of the switch 416. It may be a thing.
  • the sheet electrode 430 is attached to the end of the extension portion 420 opposite to the apparatus main body 410.
  • a conductive wire as a conductive portion is extended inside the extension portion 420.
  • the sheet electrode 430 has the same configuration, operation, and effect as the sheet electrode 50 of the first embodiment, and detailed description thereof will be omitted.
  • the beauty device 500 includes a device main body 510 and a sheet electrode 530 similar to the sheet electrode 50 of the first embodiment. Similar to the first embodiment, the beauty device 500 detachably attaches the sheet electrode 530 forming the skin electrode to the surface of the user's skin S, and the device main body 510 and the sheet are provided by the conductor as the conductive portion. It is designed to be used by electrically connecting it to the electrode 530. That is, the beauty device 500 constitutes a beauty device used by being attached to the surface of the skin S of the human body, particularly the human face.
  • the device main body 510 has at least a hollow housing 512 that houses an oscillator, a control unit, and a battery, similar to the housing of the first embodiment.
  • the housing 512 has first and second arm portions 542 and 544, and the first and second arm portions 542 and 544 are connected to each other at one end of each joint portion 540.
  • the first and second arm portions 542 and 544 are formed in a dogleg shape so that the angle around the joint portion 540 does not become 180 °, that is, they do not line up in a straight line.
  • the housing 512 forms an engaging portion in which the inner side walls 542b and 544b of the first and second arm portions 542 and 544 engage with the wearer's ear around the joint portion 540.
  • a ground electrode is provided on either or both of the inner side walls 542b and 544b of the first and second arm portions 542 and 544.
  • the beauty device 500 includes an extension portion 520 extending between the device main body 510 and the sheet electrode 530.
  • the extension portion 520 can be formed from a hollow member.
  • the extension 520 is coupled to the housing 512 at one end thereof. More specifically, the extension portion 520 is coupled to the tip portion 542a of the first arm portion 542 opposite to the coupling portion 540, while the extension portion 520 is connected to one of the first and second arm portions 542 and 544. ing.
  • the device body 510 also has a switch 516 that turns the beauty device 500, in particular the oscillator housed in the housing 512, on and off.
  • the switch 516 is arranged on the outer wall 544a of the second arm portion. The switch 516 is touched or pushed in to turn it on and off.
  • the position and shape of the switch 516 are not limited, and any one can be used, and the control unit is wirelessly operated remotely by a wireless operation device similar to the wireless operation device 70 of the first embodiment instead of the switch 516. It may be a thing.
  • the sheet electrode 530 is attached to the end portion of the extension portion 520 opposite to the apparatus main body 510.
  • a conductive wire as a conductive portion is extended inside the extension portion 520, and is introduced into the housing 512 from the tip portion 542a of the first arm portion 542.
  • the sheet electrode 530 has the same configuration, operation, and effect as the sheet electrode 50 of the first embodiment, and detailed description thereof will be omitted.
  • the adhesive layer used for the skin electrode may be any material as long as it has a holding force when it adheres to the skin and does not cause pain when peeled off, and is applied, impregnated, or adhered to one surface of the support material. It is provided by means such as flow.
  • Preferred examples of the adhesive component include various water-soluble polymers, oil-soluble polymers, and gel agents obtained by partially modifying these by means such as cross-linking.
  • the type of cross-linking agent, compounding agent, and compounding condition can be selected from known methods.
  • water-soluble polymers examples include polyacrylic acid, polyacrylic acid salt, polymethacrylic acid, polymethacrylate, polyvinyl alcohol, polyvinylpyrrolidone, polyacrylamide, polyacrylamide salt, polymethacrylamide, polymethacrylate salt, and methacryloyl.
  • oil-soluble polymer examples include a pressure-sensitive adhesive composed of a vinyl acetate / crotonic acid copolymer, a vinyl propionate / crotonic acid copolymer, a vinyl acetate resin, a trimethylsiloxysilicate polymer, a silicon resin or an acrylic polymer.
  • Rubber-based pressure-sensitive adhesives such as styrene-isoprene-styrene block copolymer, styrene-butadiene-styrene block copolymer, polyisoprene, poloisobutylene, and polybutadiene, silicone-based pressure-sensitive adhesives such as silicone rubber, dimethylsiloxane base, and diphenylsiloxane base.
  • Vinyl ether-based pressure-sensitive adhesives such as polyvinyl methyl ether, polyvinyl ethyl ether, polyvinyl isobutyl ether, vinyl ester-based pressure-sensitive adhesives such as vinyl acetate-ethylene copolymer, carboxylic acid components such as dimethyl terephthalate, dimethyl isophthalate, and dimethyl phthalate, and ethylene.
  • Polyester-based pressure-sensitive adhesive composed of polyhydric alcohol components such as glycol, various rubber-based polymers, acrylic-modified silicon resin, acrylic-modified silicon resin, epoxy resin, polyacrylonitrile, or co-polymerization of these polymerizable monomer raw materials with other polymerizable monomers. Examples include polymers.
  • the material that forms the microneedles to which the adhesive layer can be applied may be any material that exhibits a certain degree of hardness so as to pierce the skin and cause irritation, and the material itself is not particularly limited. However, since it is applied to the skin for a long time, it needs to be a biocompatible material, and is preferably formed of a material that can be dissolved or swollen in the living body. Examples of such a material include polysaccharides such as hyaluronic acid, chitosan, maltose, arginate, amylose and agarose, celluloses such as carboxymethyl cellulose and hydroxypropyl cellulose, starch and the like, which are formed by each material alone.
  • polysaccharides such as hyaluronic acid, chitosan, maltose, arginate, amylose and agarose
  • celluloses such as carboxymethyl cellulose and hydroxypropyl cellulose, starch and the like, which are formed by each material alone.
  • a particularly preferred material is hyaluronic acid.
  • it may be formed of a resin that does not dissolve or swell in the living body and does not affect the living body.
  • a resin that does not dissolve or swell in the living body and does not affect the living body.
  • water-soluble drug and cosmetic ingredients conventionally used as transdermal absorption preparations such as ascorbyl palmitate, kodiic acid, lucinol, tranexamic acid, potassium 4-methoxysalicylate, and oil-based licorice.
  • Whitening ingredients such as extracts and vitamin A derivatives;
  • Anti-wrinkle ingredients such as retinol, retinoic acid, retinol acetate, retinol palmitate; Blood circulation promoting ingredients such as tocopherol acetate, capsine, salicylic acid vanillylamide; raspberry ketone, evening primrose extract, seaweed extract, etc.
  • Diet components antibacterial components such as isopropylmethylphenol, photosensitizer, and zinc oxide; medicinal components such as vitamins such as vitamin D2, vitamin D3, and vitamin K may be added.
  • the present invention also provides a beauty method for improving the skin condition of a subject, including applying the beauty device to the skin of the subject hands-free. Improvement of the subject's skin condition includes promotion of collagen production, promotion of moisturization, or improvement of wrinkles in the subject's skin.
  • the method of the invention has a current value in the range of 100-1000 ⁇ A, preferably 150-1000 ⁇ A, more preferably 200-500 ⁇ A and 100-5000 Hz, more preferably 200-5000 Hz, even more preferably 500-2000 Hz. It comprises the step of applying an electrical stimulus to the skin by an alternating current having a frequency in the range of.
  • the cosmetological device / method of the present invention promotes the production of skin collagen.
  • the measurement of the ability to produce skin collagen may be performed by a well-known method and is not particularly limited.
  • the amount of collagen in fibroblasts can be measured using, for example, a commercially available collagen measurement kit.
  • it can be measured by utilizing the fact that 3,4-DHPAA selectively binds to a peptide having glycine at the N-terminal and emits fluorescence, as in the collagen quantification kit of Cosmo Bio Co., Ltd. described in Examples. ..
  • Collagen constituting the skin includes type I, type III, type IV, type V, type XII, type XIV and the like, and is not particularly limited in the present invention. good.
  • the beauty device of the present invention can be applied to, for example, 1 to 480 minutes, 1 to 240 minutes, 1 to 180 minutes, 1 to 120 minutes, 20 to 180 minutes, 20 to 120 minutes, 60 to 120 minutes, and fibroblasts.
  • the amount of collagen in skin cells such as cells is, for example, 1.1 times, 1.2 times, 1.3 times, 1.4 times, 1.5 times, 2.0 times, as compared with the case where nothing is applied.
  • the effect of increasing by 3.0 times, 6.0 times, or more is achieved.
  • the beauty device / method of the present invention can be applied for a long time, it is easy to apply a period longer than the above time. Further, such electrical stimulation may be performed a plurality of times.
  • the collagen production promoting effect of the present invention is achieved by applying an alternating current to the skin at a constant frequency.
  • the alternating current is 100 Hz to 5000 Hz, preferably 200 Hz to 5000 Hz, and more preferably 500 Hz to 2000 Hz.
  • the microcurrent generated by cosmetic devices and devices for wounds, etc., which are usually on the market, is mainly about 0.1 Hz to 10 Hz, but the inventors of the present application apply a specific frequency higher than these. It was found to promote the production of skin collagen.
  • facial equipment, massage equipment, and the like include those using electromagnetic waves having a frequency of about 0.3 to 300 MHz such as RF waves, and those using ultrasonic waves having a frequency of about 1 MHz to 7 MHz.
  • the frequencies adopted by the cosmetological devices / methods of the present invention are extremely low. If a strong frequency like a conventional facial device is given to the skin, there is a risk of adverse effects such as redness, pressure marks, scars, pain, and inflammation on the skin, but if a frequency like the present invention is adopted, the above-mentioned risk is low. Non-invasive stimulation is possible.
  • the alternating current can be arbitrarily selected from 100 ⁇ A to 1000 ⁇ A, 150 ⁇ A to 1000 ⁇ A, 200 ⁇ A to 500 ⁇ A, and the like. It is preferably 200 ⁇ A to 500 ⁇ A. Since the current value in such a range is equivalent to the current value in human skin, there is little adverse effect on the skin.
  • the voltage can be arbitrarily selected from 1.0 V to 10.0 V, etc., 5.0 V to 10.0 V, etc., 1.0 V to 5.0 V, etc., within a range that does not adversely affect the skin.
  • the current and voltage waveforms can be arbitrarily set such as pulse-shaped, square wave, sine wave, triangular wave, and sawtooth wave.
  • the alternating current conductive to the skin is 1 to 480 minutes, 1 to 240 minutes, 1 to 120 minutes, 5 to 120 minutes, 20 to 180 minutes, 20 to 120 minutes, 60 to 120 minutes, 20 to 60 minutes. It can be arbitrarily selected within a range that does not adversely affect the skin, such as minutes and 20 to 40 minutes. It is preferably 1 to 120 minutes.
  • the beauty device of the present invention Since the beauty device of the present invention is inconspicuously worn, it can be used for going out, etc., and the stimulus for the above time can be applied multiple times, such as twice, three times, four times, etc., or longer than the above time. It is also possible to give a stimulus of time. A higher effect is expected by applying the stimulus for a longer time or multiple times.
  • the frequency is daily, 2 days, 3 days, 4 days, 5 days, 6 days, 7 days, once every 1, 2, 3, 4 weeks, etc., continuously or intermittently, regularly or irregularly. It may be done in a targeted manner.
  • the cosmetological device / method of the present invention may have an effect of promoting moisturizing of the skin.
  • the moisturizing promoting effect can be measured, for example, the amount of water in the skin, the amount of transepidermal water loss (TEWL), or the like using an arbitrary skin water content checker such as a corneometer.
  • the beauty device / method of the present invention applies an alternating current specified in the present invention for 1 to 480 minutes, 1 to 240 minutes, 1 to 120 minutes, 20 to 120 minutes, 60 to 120 minutes, 20 to 60 minutes, 20 minutes.
  • a corneometer When applied for ⁇ 40 minutes, for example, even if 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 480 minutes, 24 hours, 36 hours or more have passed after application, for example, a corneometer is applied.
  • a moisturizing promoting effect such that a water content of 35 au, 30 au, 25 au, 20 au, 15 au or more can be continuously maintained as compared with the previous value is exhibited. Further, since the beauty device of the present invention can be applied for a long time, a further moisturizing promoting effect is expected.
  • the beauty device / method of the present invention may have a wrinkle improving effect.
  • the wrinkle improvement effect is obtained by visual inspection, judgment by a trained measurer, or image analysis, for example, image analysis of a photographic drawing taken by an Intera 3D camera (Gaderius) specifically shown in the embodiment of the present application. ) Can be measured.
  • Wrinkle improvement effect can be expected for hours, 5 hours, 7 hours, 12 hours, 24 hours, 36 hours, 48 hours, 60 hours, 72 hours or more.
  • the beauty device of the present invention is applied for 20 minutes and repeated once, or twice, three times or more at specific time intervals such as 6 hours, 12 hours, 24 hours and 48 hours. Therefore, for example, according to the dent index by image analysis using an Antera 3D camera, a wrinkle improving effect such as a reduction of 5.0, 6.0, 7.0, 8.0, 9.0 or more can be achieved. Further, since the beauty device of the present invention can be applied for a long time, further wrinkle improving effect is expected.
  • the subject to which the method of the present invention is applied is a subject to which collagen deficiency, water content deficiency, and wrinkles are objectively or subjectively recognized, but it is desired to prevent collagen deficiency, water content deficiency, and wrinkles. It may be the desired object.
  • the subject may be a subject judged to be deficient in collagen or water content or deeply wrinkled, or may be a subject to be concerned about, for example, dry skin, wrinkles, swelling, or decreased elasticity.
  • the amount of collagen, the amount of water, wrinkles, elasticity, elasticity and the like can be determined by using a known index such as visual judgment, subjective or objective evaluation, a cute meter value, or the above-mentioned method.
  • the collagen production promoting effect, moisturizing promoting effect, and wrinkle improving effect of the present invention can be measured not only by the above-mentioned methods but also by any method such as in vivo, in vitro, ex vivo, in situ.
  • the beauty device of the present invention is provided with additional functions such as ion introduction function, ion derivation function, EMS, sound wave vibration, radio wave generation function, LED generation function, heating function, cooling function and the like, if necessary. May be good.
  • the cosmetology device / method of the present invention may be used in combination with other treatments.
  • Other treatments include, but are not limited to, application of various stimuli such as the above-mentioned light stimulus and physical stimulus, application of stimulus by human hand, application of cosmetics, and the like.
  • any cosmetics such as gel, cream, lotion, hyaluronic acid, collagen, vitamins, and moisturizers that promote the beauty effect are used in combination with the skin, and the present invention is applied on the skin. You may apply the beauty equipment by wearing the sheet.
  • the method of the present invention is intended for beauty and may not be a treatment method used by doctors and medical professionals.
  • the present invention also provides a cosmetological counseling method that supports a cosmetological act of the subject, including presenting the cosmetological method / device of the present invention to the subject.
  • Example 1 ⁇ Collagen production promoting action by electrical stimulation> METHODS:
  • a cell reactor was prepared by the method described in N. Tandon et al., Nat. Protocol. 4 (2009) 155-173.
  • Human fibroblasts Normal Human Thermal Fiberblast, manufactured by ATCC, USA
  • a pulse wave generating device is used to apply 1 Hz, 500 Hz, 2000 Hz pulse waves (5 V, 5 ⁇ A).
  • the stimulus was given for 2 hours.
  • FIG. 6 shows a waveform in the case of 2000 Hz. Even in the case of 1 Hz and 500 Hz, they have the same pulse-like waveform except that only the frequency is different.
  • the amount of collagen in fibroblasts was measured as follows using a Sircol TM soluble collagen assay kit (Biocolor Ltd.). 1.0 ml of Sircol TM dye reagent is added to a tube containing 100 ⁇ l of the above fibroblast supernatant. Cover the tube and mix manually at 5 minute intervals for a total of 30 minutes. The tube is then transferred to a microcentrifuge to remove unbound dye by suction. After adding 750 ⁇ l of ice-cold acid-salt wash reagent, transfer the tube to a microcentrifuge and centrifuge at 12,000 rpm for 10 minutes. The acid-salt cleaning reagent is removed by suction and 250 ⁇ l of alkaline reagent is added to each tube.
  • a Sircol TM soluble collagen assay kit Biocolor Ltd.
  • the collagen-binding pigment is released into the solution using a vortex mixture. Then, 200 ⁇ l of the solution in each tube is transferred to the wells of the 96-well plate. Read at 555 nm using a plate reader (Thermo Electron Corporation). The quantification is performed by triplicate, and the case where no electrical stimulation is applied to the cells is used as a control and contrasted. The concentration of collagen produced is determined by contrasting with the calibration curve and standardized by the number of cells lysed by the assay.
  • the results are shown in FIG.
  • the frequencies were 500 Hz and 2000 Hz
  • high collagen production promoting effects were observed, about 2.0 times and about 6.0 times, respectively, as compared with the subject.
  • remarkable collagen production is observed when the frequency is 2000 Hz, and it can be seen that the higher the frequency, the more the collagen production is promoted.
  • the apparatus of the present invention has the effect of promoting collagen production in skin cells simply by applying a skin electrode to the skin and applying a pulse wave at a high frequency.
  • Example 2 ⁇ Moisturizing effect by electrical stimulation> Subject: 10 healthy men in their 40s and 60s who have no skin problems
  • Equipment used ⁇ Iontophoresis (IP) box device (self-made) ⁇ Omron skin gel pad (conductive electrode (carbon black) adhesive gel, model number: HVLLPAD) 2 cm x 2 cm -Courage + Khazaka Corneometer (model number: CM825)
  • Method The experiment was performed at a temperature of 24 ° C. and a humidity of 45%. After washing the skin with soap and water to remove water, the skin water content was measured with a corneometer. The gel pad was attached to the skin.
  • the gel pad was connected to an IP box device and the skin was subjected to electrical stimulation of 5 V, 250 ⁇ A, 500 Hz pulse waves for 20 minutes.
  • the pad was removed from the skin, and at 15, 30, 45, and 60 minutes, the water content of the skin was measured over time with a corneometer. As a control, the water content was also measured when the cosmetic was applied for the same time without the pulse wave and when neither the pulse wave nor the cosmetic was given.
  • the results of skin moisture content are shown in FIG. It can be seen that after 20 minutes of application, a water content of 20 au or more is maintained for 60 minutes or more after application. The effect was remarkable even when compared with the control using only the cosmetics.
  • the device of the present invention can increase the water content of the skin and moisturize the skin simply by applying a skin electrode to the skin and applying a pulse wave at a high frequency.
  • Example 3> ⁇ Wrinkle improvement effect by pulse wave stimulation> The same electrical stimulation was applied to the same subjects as in Example 2 except that wrinkles were measured by the following method instead of water content measurement, and the wrinkle improvement effect was investigated. Skin wrinkles were imaged using an ANTERA 3D camera for skin analysis.
  • the results are shown in FIG.
  • the figure below shows an actual photograph of the skin taken with an ANTERA 3D camera
  • the figure above is an image of the surface morphology of the part of the skin corresponding to the figure below. It can be seen that the wrinkle improving effect is maintained even after 7 hours have passed and 48 hours have passed since the stimulus was applied for 20 minutes.
  • the device of the present invention has an effect of improving wrinkles on the skin simply by applying a skin electrode to the skin and applying a pulse wave at a high frequency.
  • Example 4> ⁇ Wrinkle improving effect by multiple electrical stimuli> The same subjects as in Examples 2 and 3 were given the same 20-minute electrical stimulation except that the electrical stimulation was applied three times after 0 hour, 24 hours, and 48 hours. Skin wrinkles were imaged using an ANTERA 3D camera and the wrinkle depth was quantified by determining the Indentation Index ( ⁇ m) using Miravex 1 software.
  • the result of wrinkle measurement is shown in FIG. It decreased by about 6.0 by the first stimulus, but then returned to the original level, but decreased by about 2.0 by the second stimulus and further decreased by the third stimulus. It was found that the wrinkle improving effect was further enhanced by applying a plurality of stimuli in this way as compared with a single stimulus.
  • the beauty device of the present invention has the effects of promoting collagen production in the skin, moisturizing, and improving wrinkles.
  • the collagen production of the skin is promoted, moisturized, and wrinkles are improved, it is effective for the elasticity and elasticity of the skin.
  • Example 5 For the purpose of demonstrating that the device of the present invention exerts an excellent cosmetic effect, the effect was compared with a commercially available facial device. Another company's product was used as a commercially available facial device. The device activates the skin by passing a weak electric current through the skin. The wrinkle reducing effect was investigated by determining the indentation index ( ⁇ m) and quantifying the wrinkle depth in the same manner as in Example 4. The result is shown in FIG. “Before application” in measurement 1 on the left side of the figure indicates the dent index of the application site immediately before application by another company's product. “Gel application” in measurement 2 indicates the dent index of the skin area to which only gel application is applied.
  • the dent index in which only the gel application was applied was measured. “After application” in measurement 3 indicates the dent index at the location where the gel was applied and the current stimulus was applied.
  • the current stimulation was performed by giving the current stimulation to the skin for 5 minutes according to the instruction manual of the product of another company. Since there is no difference in the dent index between measurements 2 and 3, it is considered that the effect seen by applying the products of other companies is not the effect of electrical stimulation but the effect of gel application. Therefore, it can be seen that the wrinkle reduction effect of the current stimulation of other companies' products cannot be expected so much if it is limited to the effect using the dent index as an index.
  • the right side of FIG. 23 shows the amount of change in the depression index with respect to “before application” of measurement 1.
  • the amount of change "after application” is the value obtained by subtracting the amount of change in ⁇ gel application only> from the amount of change in ⁇ gel application + current stimulation>, and the effect of using the dent index as an index is the current stimulation by other companies' products. It is clear from this figure that we cannot expect it.
  • FIG. 24 shows the amount of change in the depression index with respect to “before application”. From both figures, the wrinkle improvement effect using the dent index as an index cannot be expected with the current stimulation by the products of other companies, but the clear effect was confirmed by the apparatus of the present invention.
  • the beauty device of the present invention has the effects of promoting collagen production in the skin, moisturizing, and improving wrinkles.
  • the collagen production of the skin is promoted, moisturized, and wrinkles are improved, it is effective for the elasticity and elasticity of the skin.
  • the beauty device of the present invention preferably a wearable beauty device, can be used hands-free, it can be worn while working, and can be worn while working, commuting, shopping, etc. It is easy to carry because it is small and light.
  • such beauty equipment enables long-term application and repeated application.

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