WO2022109908A1

WO2022109908A1 - Method and system for adjusting vascular stenosis zone, and storage medium

Info

Publication number: WO2022109908A1
Application number: PCT/CN2020/131704
Authority: WO
Inventors: 王之元; 刘广志; 王鹏; 徐磊
Original assignee: 苏州润迈德医疗科技有限公司
Priority date: 2020-11-25
Filing date: 2020-11-26
Publication date: 2022-06-02
Also published as: CN112472112B; CN112472112A

Abstract

A method and a system for adjusting a vascular stenosis zone, and a storage medium. Said method comprises: acquiring a corrected tube diameter curve of a blood vessel (S100); acquiring a start point and an end point of a vascular stenosis and a vascular stenosis zone (S200); respectively providing marks on the start point and the end point (S300); providing a sliding rod on the corrected tube diameter curve, one end of the sliding rod corresponding to the start point, and the other end of the sliding rod corresponding to the end point (S400); and if the sliding rod is slid, said marks respectively corresponding to the start point and the end point slide by corresponding distances on the corrected tube diameter curve, i.e. adjusting the vascular stenosis zone (S500). In said method, distortion of direct definition of a vascular stenosis zone is avoided, and the concept of human factors engineering is integrated, by means of a sliding rod, into the operation and design for adjusting the vascular stenosis zone. The combination of manual interaction and automated determination effectively improves accuracy, reduces the risk of using the automated determination algorithm only, and increases the robustness of the whole system.

Description

Method, system and storage medium for adjusting vascular stenosis interval

technical field

The present invention relates to the technical field of coronary medicine, in particular to a method, a system and a storage medium for adjusting a vascular stenosis interval.

Background technique

The deposition of lipids and carbohydrates in human blood on the blood vessel wall will form plaques on the blood vessel wall, which will then lead to vascular stenosis; especially the vascular stenosis near the coronary arteries of the heart will lead to insufficient blood supply to the heart muscle and induce coronary heart disease. , angina pectoris and other diseases pose a serious threat to human health. According to statistics, there are about 11 million coronary heart disease patients in my country, and the number of patients treated with cardiovascular interventional surgery is increasing by more than 10% every year.

Although conventional medical detection methods such as coronary angiography (CAG) and computed tomography (CT) can display the severity of coronary artery stenosis, they cannot accurately evaluate coronary ischemia. In order to improve the accuracy of coronary vascular function evaluation, in 1993, Pijls proposed a new index for calculating coronary vascular function through pressure measurement - Fractional Flow Reserve (FFR). After long-term basic and clinical research, FFR It has become the gold standard for functional evaluation of coronary stenosis.

FFR is one of the coronary vascular evaluation parameters, and the microcirculation resistance index IMR belongs to the coronary vascular evaluation parameters.

The existing technology always tries to automatically determine the stenosis interval of blood vessels through algorithms. However, due to the errors brought by the imaging equipment and the diversity of the patient's blood vessel conditions, it is impossible to obtain the correct stenosis every time only through pixel information. In the process of automatically judging the stenosis interval of the blood vessel through the algorithm, the user must reconfirm the result based on his own experience.

SUMMARY OF THE INVENTION

The invention provides a method, a system and a storage medium for adjusting the stenosis interval of blood vessels, so as to solve the problem that the stenosis interval of blood vessels cannot be automatically and accurately judged by algorithm alone, and provide a suitable manual interaction tool for users to adjust and confirm the results. .

In order to achieve the above objects, in a first aspect, the present application provides a method for adjusting a vascular stenosis interval, including:

Obtain the corrected diameter curve of the blood vessel;

Obtain the start point, end point and stenosis interval of vascular stenosis;

respectively setting marks on the starting point and the ending point;

A sliding rod is arranged on the corrected pipe diameter curve, one end of the sliding rod corresponds to the starting point, and one end of the sliding rod corresponds to the ending point;

If the sliding rod is slid, the marks corresponding to the start point and the end point respectively slide corresponding distances on the corrected diameter curve, that is, the vascular stenosis interval is adjusted.

Optionally, in the above-mentioned method for adjusting a blood vessel stenosis interval, the method for obtaining a corrected diameter curve of a blood vessel includes:

Obtain the real diameter curve from the coronary angiography image;

Fit the normal blood vessel diameter and obtain the fitted diameter curve;

According to the fitted diameter curve and the real diameter curve, obtain the stenotic lesion vessel segment;

The diameter curve obtained from the stenotic lesion vessel segment is a corrected diameter curve.

Optionally, in the above-mentioned method for adjusting a vascular stenosis interval, the method for obtaining a stenotic lesion vessel segment according to the fitted caliber curve and the true caliber curve includes:

obtaining the first stenotic lesion interval according to the fitted diameter curve and the real diameter curve;

Remove the misjudged stenotic region from the first stenotic lesion interval to obtain a second stenotic lesion interval;

Re-fit the diameter interval curve according to the second stenosis lesion interval to obtain stenosis points;

Obtaining the third stenosis lesion interval according to the stenosis point, that is, the precise stenosis lesion interval, the stenosis start point and the end point;

The diameter curve obtained in the third stenosis lesion interval is a corrected diameter curve.

Optionally, in the above-mentioned method for adjusting a vascular stenosis interval, the method for fitting a normal vascular diameter and obtaining a fitting diameter curve includes:

According to the fitting cost function, the fitted pipe diameter is obtained, and the specific formula is:

Among them, i represents the curve sampling point of the ith pipe diameter; n represents the sum of the number of pipe diameter curve sampling; _xi represents the length of the curve sampling point of the ith pipe diameter; y _i represents the pipe diameter at _xi ;

Corresponding each of the fitted pipe diameters to a coordinate system to obtain a corresponding pipe diameter point, and smoothly connecting the pipe diameter points in turn to obtain the fitted pipe diameter curve.

Optionally, in the above-mentioned method for adjusting a vascular stenosis interval, the method for obtaining the first stenosis interval according to the fitted caliber curve and the true caliber curve includes:

Obtain the true diameter of the blood vessel;

Corresponding the real pipe diameter to the coordinate system of the fitted pipe diameter curve;

Obtain the true pipe diameter curve, and the intersection of the true pipe diameter curve and the fitted pipe diameter curve;

If the real pipe diameter at a point before the intersection is larger than the fitted pipe diameter, the intersection is the first entry point of the narrow area, otherwise, the intersection is the first exit of the narrow area point;

The curve between the first entry point and the first exit point is the preliminarily determined stenosis position, that is, the first stenotic lesion interval.

Optionally, in the above-mentioned method for adjusting a vascular stenosis interval, the method for removing a misjudged stenosis area from the first stenotic lesion interval to obtain a second stenotic lesion interval includes;

Calculate stenosis;

calculating the length L of the blood vessel centerline of the first stenotic lesion interval;

A second stenotic lesion interval is obtained by removing a misjudged stenotic region from the first stenotic lesion interval according to the stenosis degree and/or the blood vessel centerline length.

Optionally, in the above-mentioned method for adjusting a vascular stenosis interval, the method for calculating a stenosis degree includes:

Among them, A represents the stenosis degree of the blood vessel, D _min represents the minimum diameter of the blood vessel between the first entry point and the first exit point, D _in and D _out represent the vessel diameter of the first entry point and the first exit point, respectively vascular diameter.

Optionally, in the above-mentioned method for adjusting a vascular stenosis interval, the method for obtaining a second stenotic lesion interval by removing a misjudged stenotic area from the first stenotic lesion interval according to the stenosis degree and/or the length of the blood vessel centerline include:

If A<0.2, it is judged as a misjudged area, and the fitted pipe diameter curve in this area is used to replace the real pipe diameter curve in the misjudged area;

If L<5mm, it is judged as a misjudged area, and the fitted pipe diameter curve in this area is used to replace the real pipe diameter curve in the misjudged area;

The stenotic area obtained after removing the misjudged area is the second stenotic lesion interval.

Optionally, in the above-mentioned method for adjusting a vascular stenosis interval, the method for refitting a vessel diameter interval curve according to the second stenotic lesion interval, and the method for obtaining a stenosis point includes:

Take the area between 1-3 cm before the first entry point and 1-3 cm after the first exit point, and re-fit the pipe diameter interval curve according to the fitting cost function;

The point with the smallest pipe diameter in the refitted pipe diameter interval curve is obtained as the stenosis point.

Optionally, in the above-mentioned method for adjusting a vascular stenosis interval, the method for obtaining a third stenosis lesion interval according to the stenosis point, that is, a precise stenosis lesion interval, includes:

On both sides of the narrow point, the two points where the fitted pipe diameter interval curve and the real pipe diameter curve intersect are a second entry point and a second exit point, and the second entry point and the second The interval between the exit points is the third stenotic lesion interval, the second entry point is the stenosis start point, and the second exit point is the stenosis exit point.

In a second aspect, the present application provides a system for adjusting a vascular stenosis interval, including: a device for obtaining a vessel diameter curve, a device for obtaining a vascular stenosis interval, a marking device and a sliding device;

The device for obtaining the diameter curve is used to obtain the corrected diameter curve of the obtained blood vessel;

The vascular stenosis interval acquisition device is connected to the vessel diameter curve acquisition device, and is used for acquiring the vascular stenosis starting point, the ending point and the vascular stenosis interval;

the marking device, which is connected to the vascular stenosis interval acquiring device, is used for setting markers on the starting point and the ending point respectively;

The sliding device is connected with the tube diameter curve acquisition device, the blood vessel stenosis interval acquisition device, and the marking device, and is used to set a sliding rod on the corrected tube diameter curve, and one end of the sliding rod corresponds to the The starting point, one end of the sliding rod corresponds to the ending point; if the sliding rod is slid, the marks corresponding to the starting point and the ending point respectively slide corresponding distances on the corrected pipe diameter curve, that is, The vascular stenosis interval is adjusted.

Optionally, in the above-mentioned system for adjusting a vascular stenosis interval, the device for obtaining a vascular stenosis interval includes a first stenosis lesion unit, a second stenosis lesion unit, a stenosis point unit and a third stenosis lesion unit;

The first stenosis lesion unit is connected to the vessel diameter curve obtaining device, and is configured to obtain the first stenosis lesion interval according to the fitted vessel diameter curve and the real vessel diameter curve;

the second stenotic lesion unit, connected to the first stenotic lesion unit, and configured to remove a misjudged stenotic region from the first stenotic lesion interval to obtain a second stenotic lesion interval;

The stenosis point unit is connected to the pipe diameter curve obtaining device, and is used for obtaining the stenosis point according to the fitted pipe diameter interval curve;

The third stenosis lesion unit is connected to the stenosis point unit and the vessel diameter curve acquisition device, and is used for acquiring a third stenosis lesion interval according to the stenosis point, that is, a precise stenosis lesion interval.

In a third aspect, the present application provides a computer storage medium, and when the computer program is executed by a processor, the above-mentioned method for adjusting a blood vessel stenosis interval is implemented.

The beneficial effects brought by the solutions provided in the embodiments of the present application include at least:

The present application provides a method for adjusting the vascular stenosis interval, a method for realizing manual interaction and automatic algorithm coordination through a sliding rod, integrating the concept of human factors engineering into the operation and design of adjusting the vascular stenosis interval, allowing users to quickly confirm the blood vessel Narrow range, reduce the difficulty of operation and improve work efficiency.

Description of drawings

The accompanying drawings described herein are used to provide further understanding of the present invention and constitute a part of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention. In the attached image:

1 is a flowchart of a method for adjusting a vascular stenosis interval according to the present application;

Fig. 2 is the flow chart of S100 of this application;

3 is a flowchart of S120 of the application;

FIG. 4 is a flowchart of S140 of the application;

5 is a flowchart of S141 of the application;

6 is a flowchart of S142 of the application;

7 is a flowchart of S143 of the application;

8 is a structural block diagram of a system for adjusting a vascular stenosis interval according to the present application;

FIG. 9 is a structural block diagram of the apparatus 200 for obtaining a vascular stenosis interval according to the present application.

Detailed ways

In order to make the objectives, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be clearly and completely described below with reference to the specific embodiments of the present invention and the corresponding drawings. Obviously, the described embodiments are only some, but not all, embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts all belong to the protection scope of the present invention.

Various embodiments of the present invention will be disclosed in the drawings below, and for the sake of clarity, many practical details will be described together in the following description. It should be understood, however, that these practical details should not be used to limit the invention. That is, in some embodiments of the invention, these practical details are unnecessary. In addition, for the purpose of simplifying the drawings, some well-known structures and components will be shown in a simple schematic manner in the drawings.

In coronary angiography images, evaluation parameters of coronary vessels need to be calculated in combination with hydrodynamic analysis, and there is no three-dimensional mesh model of vessels for hydrodynamic analysis in the prior art.

Example 1:

As shown in FIG. 1 , the present application provides a method for adjusting a vascular stenosis interval, including:

S100 , as shown in FIG. 2 , obtain the corrected diameter curve of the blood vessel, including:

S110, obtaining a real diameter curve from the coronary angiography image;

S120, as shown in FIG. 3, fitting a normal blood vessel diameter, and obtaining a fitting diameter curve, including:

S121, obtain the fitted pipe diameter according to the fitting cost function, and the specific formula is:

S122: Corresponding each of the fitted pipe diameters to a coordinate system to obtain a corresponding pipe diameter point, and smoothly connecting the pipe diameter points in sequence to obtain the fitted pipe diameter curve.

S130, obtaining the stenotic lesion vessel segment according to the fitted diameter curve and the real diameter curve;

S140, as shown in FIG. 4, the diameter curve obtained from the stenotic lesion vessel segment is a corrected diameter curve, including:

S141, as shown in FIG. 5, according to the fitted diameter curve and the real diameter curve, obtain a first stenosis lesion interval, including:

S1411, obtaining the true diameter of the blood vessel;

S1412, corresponding to the real pipe diameter in the coordinate system of the fitted pipe diameter curve;

S1413, obtaining the real pipe diameter curve and the intersection of the real pipe diameter curve and the fitted pipe diameter curve;

S1414, if the real pipe diameter at a point before the intersection is greater than the fitted pipe diameter, the intersection is the first entry point of the narrow area, otherwise, the intersection is the first entry point of the narrow area an exit point;

S1415, the curve between the first entry point and the first exit point is the initially determined stenosis position, that is, the first stenotic lesion interval.

S142 , as shown in FIG. 6 , remove the misjudged stenotic region from the first stenotic lesion interval to obtain a second stenotic lesion interval, including:

S1421, calculate the stenosis, the specific formula:

S1422, calculating the length L of the blood vessel centerline of the first stenotic lesion interval;

S1423, remove the misjudged stenosis region from the first stenosis lesion interval according to the stenosis degree and/or the length of the blood vessel centerline to obtain a second stenosis lesion interval, including:

1) if A<0.2, then it is judged to be a misjudged area, and the fitted pipe diameter curve of this area is used to replace the true pipe diameter curve in the misjudged area;

II) If L<5mm, it is judged as a misjudged area, and the fitted pipe diameter curve in this area is used to replace the real pipe diameter curve in the misjudged area;

III) The stenotic region obtained after removing the misjudged region is the second stenotic lesion interval.

S143 , as shown in FIG. 7 , re-fitting the diameter interval curve according to the second stenosis lesion interval to obtain stenosis points, including:

S1431, take the area between 1-3 cm before the first entry point and 1-3 cm after the first exit point, and re-fit the pipe diameter interval curve according to the fitting cost function;

S1432, acquiring the point with the smallest pipe diameter in the re-fitted pipe diameter interval curve as the stenosis point.

S144, obtaining a third stenosis lesion interval according to the stenosis point, that is, an accurate stenosis lesion interval, a stenosis start point and an end point, including: on both sides of the stenosis point, the fitted diameter interval curve and the real tube diameter interval The two points where the diameter curve intersects are the second entry point and the second exit point, the interval between the second entry point and the second exit point is the third stenotic lesion interval, and the second entry point is the stenosis The starting point, the second exit point is the narrow exit point.

S145, the diameter curve obtained in the third stenosis lesion interval is a corrected diameter curve.

S200, obtaining the starting point, the ending point and the stenosis interval of blood vessel stenosis;

S300, setting marks on the starting point and the ending point respectively;

S400, setting a sliding rod on the corrected pipe diameter curve, one end of the sliding rod corresponds to the starting point, and one end of the sliding rod corresponds to the ending point;

S500 , if the sliding rod is slid, the marks corresponding to the start point and the end point respectively slide by a corresponding distance on the corrected diameter curve, that is, the vascular stenosis interval is adjusted.

As shown in FIG. 8 , the present application provides a system for adjusting a vascular stenosis interval, including: a vessel diameter curve obtaining device 100 , a vessel stenosis interval obtaining device 200 , a marking device 300 and a sliding device 400 ; the vessel diameter curve obtaining device 100, used to obtain the modified diameter curve of the obtained blood vessel; the vessel stenosis interval obtaining device 200, connected to the vessel diameter curve obtaining device 100, is used to obtain the starting point, the ending point and the vessel stenosis interval of the vessel stenosis; the The marking device 300 is connected to the vascular stenosis interval obtaining device 200, and is used to set markers on the starting point and the ending point respectively; the sliding device 400 is connected to the vessel diameter curve obtaining device 100, the The vascular stenosis interval acquisition device 200 is connected to the marking device 300, and is used to set a sliding rod on the corrected diameter curve, one end of the sliding rod corresponds to the starting point, and one end of the sliding rod corresponds to the end point If the sliding bar is slid, the marks corresponding to the starting point and the ending point will slide corresponding distances on the corrected diameter curve, that is, the vascular stenosis interval is adjusted.

As shown in FIG. 9 , in an embodiment of the present application, the device 200 for obtaining a vascular stenosis interval includes a first stenosis lesion unit 210 , a second stenosis lesion unit 220 , a stenosis point unit 230 and a third stenosis lesion unit 240 ; A stenosis lesion unit 210, connected to the vessel diameter curve obtaining device 100, for obtaining a first stenosis lesion section according to the fitted vessel diameter curve and the real vessel diameter curve; the second stenosis lesion unit 220, connected to The first stenotic lesion unit 210 is connected to remove the misjudged stenotic region from the first stenotic lesion interval to obtain a second stenotic lesion interval; the stenosis point unit 230 is connected to the vessel diameter curve acquisition device The third stenosis lesion unit 240 is connected to the stenosis point unit 230 and the vessel diameter curve obtaining device 100, and is used for obtaining the stenosis point according to the stenosis point. The third stenotic lesion interval is obtained, which is the precise stenotic lesion interval.

The present application provides a computer storage medium, and when the computer program is executed by a processor, the above-mentioned method for adjusting a vascular stenosis interval is implemented.

As will be appreciated by one skilled in the art, various aspects of the present invention may be embodied as a system, method or computer program product. Accordingly, various aspects of the present invention may be embodied in the form of an entirely hardware implementation, an entirely software implementation (including firmware, resident software, microcode, etc.), or a combination of hardware and software aspects, It may be collectively referred to herein as a "circuit," "module," or "system." Furthermore, in some embodiments, various aspects of the present invention may also be implemented in the form of a computer program product on one or more computer-readable media having computer-readable program code embodied thereon. Implementation of the method and/or system of embodiments of the present invention may involve performing or completing selected tasks manually, automatically, or a combination thereof.

For example, hardware for performing selected tasks according to embodiments of the invention may be implemented as a chip or a circuit. As software, selected tasks according to embodiments of the invention may be implemented as a plurality of software instructions executed by a computer using any suitable operating system. In an exemplary embodiment of the invention, one or more tasks according to exemplary embodiments of the method and/or system as herein are performed by a data processor, such as a computing platform for executing a plurality of instructions. Optionally, the data processor includes volatile storage for storing instructions and/or data and/or non-volatile storage for storing instructions and/or data, such as a magnetic hard disk and/or a Move media. Optionally, a network connection is also provided. A display and/or user input device, such as a keyboard or mouse, is optionally also provided.

Any combination of one or more computer readable may be utilized. The computer-readable medium may be a computer-readable signal medium or a computer-readable storage medium. The computer-readable storage medium can be, for example, but not limited to, an electrical, magnetic, optical, electromagnetic, infrared, or semiconductor system, apparatus or device, or a combination of any of the above. More specific examples (non-exhaustive list) of computer-readable storage media would include the following:

Electrical connection with one or more wires, portable computer disk, hard disk, random access memory (RAM), read only memory (ROM), erasable programmable read only memory (EPROM or flash memory), optical fiber, portable compact disk Read only memory (CD-ROM), optical storage device, magnetic storage device, or any suitable combination of the above. In this document, a computer-readable storage medium can be any tangible medium that contains or stores a program that can be used by or in conjunction with an instruction execution system, apparatus, or device.

A computer-readable signal medium may include a propagated data signal in baseband or as part of a carrier wave, with computer-readable program code embodied thereon. Such propagated data signals may take a variety of forms, including but not limited to electromagnetic signals, optical signals, or any suitable combination of the foregoing. A computer-readable signal medium can also be any computer-readable medium other than a computer-readable storage medium that can transmit, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device .

Program code embodied on a computer-readable medium may be transmitted using any suitable medium, including but not limited to wireless, wireline, optical fiber cable, RF, etc., or any suitable combination of the foregoing.

For example, computer program code for performing operations for various aspects of the invention may be written in any combination of one or more programming languages, including object-oriented programming languages such as Java, Smalltalk, C++, and conventional procedural programming languages, such as The "C" programming language or similar programming language. The program code may execute entirely on the user's computer, partly on the user's computer, as a stand-alone software package, partly on the user's computer and partly on a remote computer, or entirely on the remote computer or server. In the case of a remote computer, the remote computer may be connected to the user's computer through any kind of network - including a local area network (LAN) or a wide area network (WAN) - or may be connected to an external computer (eg using an Internet service provider via Internet connection).

It will be understood that each block of the flowchart illustrations and/or block diagrams, and combinations of blocks in the flowchart illustrations and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to the processor of a general purpose computer, special purpose computer or other programmable data processing apparatus to produce a machine that causes the computer program instructions when executed by the processor of the computer or other programmable data processing apparatus , resulting in means for implementing the functions/acts specified in one or more blocks of the flowchart and/or block diagrams.

These computer program instructions can also be stored on a computer readable medium, the instructions cause a computer, other programmable data processing apparatus, or other device to operate in a particular manner, whereby the instructions stored on the computer readable medium produce the An article of manufacture of instructions implementing the functions/acts specified in one or more blocks of the flowcharts and/or block diagrams.

Computer program instructions can also be loaded on a computer (eg, a coronary artery analysis system) or other programmable data processing device to cause a series of operational steps to be performed on the computer, other programmable data processing device or other device to produce a computer-implemented process , such that instructions executing on a computer, other programmable apparatus, or other device provide a process for implementing the functions/acts specified in the flowchart and/or one or more block diagram blocks.

The above specific examples of the present invention further describe the purpose, technical solutions and beneficial effects of the present invention in detail. It should be understood that the above are only specific embodiments of the present invention, and are not intended to limit the present invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

A method for adjusting a vascular stenosis interval, comprising:

Obtain the corrected diameter curve of the blood vessel;

Obtain the start point, end point and stenosis interval of vascular stenosis;

respectively setting marks on the starting point and the ending point;

A sliding rod is arranged on the corrected pipe diameter curve, one end of the sliding rod corresponds to the starting point, and one end of the sliding rod corresponds to the ending point;

If the sliding rod is slid, the marks corresponding to the start point and the end point respectively slide corresponding distances on the corrected diameter curve, that is, the vascular stenosis interval is adjusted.
The method for adjusting a blood vessel stenosis interval according to claim 1, wherein the method for obtaining the corrected diameter curve of the blood vessel comprises:

Obtain the real diameter curve from the coronary angiography image;

Fit the normal blood vessel diameter and obtain the fitted diameter curve;

According to the fitted diameter curve and the real diameter curve, obtain the stenotic lesion vessel segment;

The diameter curve obtained from the stenotic diseased vessel segment is a corrected diameter curve.
The method for adjusting a vascular stenosis interval according to claim 2, wherein the method for obtaining a stenotic lesion vessel segment according to the fitted caliber curve and the true caliber curve comprises:

obtaining the first stenosis lesion interval according to the fitted diameter curve and the real diameter curve;

Remove the misjudged stenotic region from the first stenotic lesion interval to obtain a second stenotic lesion interval;

Refit the diameter interval curve according to the second stenotic lesion interval to obtain the stenosis point;

Obtaining the third stenosis lesion interval according to the stenosis point, that is, the precise stenosis lesion interval, the stenosis start point and the end point;

The diameter curve obtained in the third stenosis lesion interval is a corrected diameter curve.
The method for regulating vascular stenosis interval according to claim 3, is characterized in that, described fitting normal blood vessel caliber, the method that obtains fitting caliber curve comprises:

According to the fitting cost function, the fitted pipe diameter is obtained, and the specific formula is:

Among them, i represents the curve sampling point of the ith pipe diameter; n represents the sum of the number of pipe diameter curve sampling; xi represents the length of the curve sampling point of the ith pipe diameter; y i represents the pipe diameter at xi ;

Corresponding each of the fitted pipe diameters to a coordinate system to obtain a corresponding pipe diameter point, and smoothly connecting the pipe diameter points in turn to obtain the fitted pipe diameter curve.
The method for adjusting a vascular stenosis interval according to claim 4, wherein the method for obtaining the first stenosis interval according to the fitted diameter curve and the real diameter curve comprises:

Obtain the true diameter of the blood vessel;

Corresponding the real pipe diameter to the coordinate system of the fitted pipe diameter curve;

Obtain the true pipe diameter curve, and the intersection of the true pipe diameter curve and the fitted pipe diameter curve;

If the real pipe diameter at a point before the intersection is larger than the fitted pipe diameter, the intersection is the first entry point of the narrow area, otherwise, the intersection is the first exit of the narrow area point;

The curve between the first entry point and the first exit point is the preliminarily determined stenosis position, that is, the first stenotic lesion interval.
The method for adjusting a vascular stenosis interval according to claim 5, wherein the method for removing a misjudged stenosis area from the first stenotic lesion interval to obtain a second stenotic lesion interval comprises;

Calculate stenosis;

calculating the length L of the blood vessel centerline of the first stenotic lesion interval;

The misjudged stenosis region is removed from the first stenotic lesion interval according to the stenosis degree and/or the length of the blood vessel centerline, so as to obtain a second stenotic lesion interval.
The method for adjusting a vascular stenosis interval according to claim 6, wherein the method for calculating the stenosis degree comprises:

Among them, A represents the stenosis degree of the blood vessel, D min represents the minimum diameter of the blood vessel between the first entry point and the first exit point, D in and D out represent the vessel diameter of the first entry point and the first exit point, respectively vascular diameter.
The method for adjusting a vascular stenosis interval according to claim 7, characterized in that, according to the stenosis degree and/or the length of the blood vessel centerline, the misjudged stenosis area is removed from the first stenotic lesion interval, and a second stenosis area is obtained. Methods of narrowing the lesion interval include:

If A<0.2, it is judged as a misjudged area, and the fitted pipe diameter curve in this area is used to replace the real pipe diameter curve in the misjudged area;

If L<5mm, it is judged as a misjudged area, and the fitted pipe diameter curve in this area is used to replace the real pipe diameter curve in the misjudged area;

The stenotic area obtained after removing the misjudged area is the second stenotic lesion interval.
The method for adjusting a vascular stenosis interval according to claim 8, wherein the method for refitting a vessel diameter interval curve according to the second stenotic lesion interval, and obtaining a stenosis point comprises:

Take the area between 1-3 cm before the first entry point and 1-3 cm after the first exit point, and re-fit the pipe diameter interval curve according to the fitting cost function;

The point with the smallest pipe diameter in the refitted pipe diameter interval curve is obtained as the stenosis point.
The method for adjusting a vascular stenosis interval according to claim 9, wherein the method for obtaining a third stenotic lesion interval, that is, an accurate stenotic lesion interval according to the stenosis point, comprises:

On both sides of the narrow point, the two points where the fitted pipe diameter interval curve and the real pipe diameter curve intersect are a second entry point and a second exit point, and the second entry point and the second The interval between the exit points is the third stenotic lesion interval, the second entry point is the stenosis start point, and the second exit point is the stenosis exit point.
A system for adjusting a vascular stenosis interval, characterized in that it comprises: a device for obtaining a caliber curve, a device for obtaining a vascular stenosis interval, a marking device and a sliding device;

The device for obtaining the diameter curve is used to obtain the corrected diameter curve of the obtained blood vessel;

The vascular stenosis interval acquisition device is connected to the vessel diameter curve acquisition device, and is used for acquiring the vascular stenosis starting point, the ending point and the vascular stenosis interval;

the marking device, which is connected to the vascular stenosis interval acquiring device, is used to set markers on the starting point and the ending point respectively;

The sliding device is connected with the tube diameter curve acquisition device, the blood vessel stenosis interval acquisition device, and the marking device, and is used to set a sliding rod on the corrected tube diameter curve, and one end of the sliding rod corresponds to the The starting point, one end of the sliding rod corresponds to the ending point; if the sliding rod is slid, the marks corresponding to the starting point and the ending point respectively slide corresponding distances on the corrected pipe diameter curve, that is, The vascular stenosis interval is adjusted.
The system for adjusting a vascular stenosis interval according to claim 11, wherein the vascular stenosis interval obtaining device comprises a first stenosis lesion unit, a second stenosis lesion unit, a stenosis point unit and a third stenosis lesion unit;

The first stenosis lesion unit is connected to the vessel diameter curve obtaining device, and is configured to obtain the first stenosis lesion interval according to the fitted vessel diameter curve and the real vessel diameter curve;

the second stenotic lesion unit, connected to the first stenotic lesion unit, and configured to remove the misjudged stenotic region from the first stenotic lesion interval to obtain a second stenotic lesion interval;

The stenosis point unit is connected to the pipe diameter curve obtaining device, and is used for obtaining the stenosis point according to the fitted pipe diameter interval curve;

The third stenosis lesion unit is connected to the stenosis point unit and the vessel diameter curve acquiring device, and is used for acquiring a third stenosis lesion interval according to the stenosis point, that is, a precise stenosis lesion interval.
A computer storage medium, characterized in that, when the computer program is executed by a processor, the method for adjusting a vascular stenosis interval according to any one of claims 1 to 10 is implemented.