WO2022099698A1 - 超声成像系统、方法和计算机存储介质 - Google Patents

超声成像系统、方法和计算机存储介质 Download PDF

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Publication number
WO2022099698A1
WO2022099698A1 PCT/CN2020/129087 CN2020129087W WO2022099698A1 WO 2022099698 A1 WO2022099698 A1 WO 2022099698A1 CN 2020129087 W CN2020129087 W CN 2020129087W WO 2022099698 A1 WO2022099698 A1 WO 2022099698A1
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WIPO (PCT)
Prior art keywords
target position
ultrasonic
ultrasound
sampling gate
sampling
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PCT/CN2020/129087
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English (en)
French (fr)
Inventor
刘硕
王勃
朱磊
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Priority to PCT/CN2020/129087 priority Critical patent/WO2022099698A1/zh
Priority to PCT/CN2021/130775 priority patent/WO2022100747A1/zh
Priority to CN202180065832.XA priority patent/CN116507287A/zh
Publication of WO2022099698A1 publication Critical patent/WO2022099698A1/zh
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Clinical applications

Definitions

  • the present application relates to the technical field of ultrasound imaging, and more particularly, to an ultrasound imaging system, method and computer storage medium.
  • ultrasound technology has become one of the most widely used, most frequently used, and one of the fastest methods of examination due to its high reliability, speed and convenience, real-time imaging, and repeatable examinations.
  • the development of new ultrasound technology has further promoted the application of ultrasound imaging in clinical diagnosis and treatment.
  • E/E', E/A, etc. obtained by ultrasound imaging are important evaluation indicators in the assessment of cardiac diastolic function.
  • the doctor needs to manually enter the pulsed Doppler imaging mode (PW mode), select the position of the sampling gate and calculate the characteristic position on the spectrum to obtain the early diastolic peak E and late diastolic flow of the mitral valve. Peak A; then re-enter tissue Doppler imaging mode (Tissue Doppler Imaging, TDI mode), select the sampling gate position again and perform characteristic position calculation on the spectral position to obtain the early diastolic peak E' and late diastolic peak A' of the annular muscle. There are many steps in the whole operation process, which affects the work efficiency of doctors.
  • a first aspect of the embodiments of the present invention provides an ultrasonic imaging method, the method comprising:
  • a second aspect of the embodiments of the present invention provides an ultrasound imaging system, the system comprising:
  • an ultrasonic probe used for transmitting a first ultrasonic wave to the heart region before setting the sampling gate, receiving an echo of the first ultrasonic wave, and acquiring a first ultrasonic echo signal based on the echo of the first ultrasonic wave, and in the sampling After the gate is set, the second ultrasonic wave is emitted to the first target position and the second target position where the sampling gate is arranged, the echo of the second ultrasonic wave is received, and the second ultrasonic echo is obtained based on the echo of the second ultrasonic wave wave signal;
  • the transmit/receive control circuit is used to control the ultrasonic probe to transmit the first ultrasonic wave before the sampling gate is set, and obtain the first ultrasonic echo signal based on the echo of the first ultrasonic wave, and control all the ultrasonic signals after the sampling gate is set.
  • the ultrasonic probe transmits a second ultrasonic wave, and obtains a second ultrasonic echo signal based on the echo of the second ultrasonic wave;
  • a processor configured to: process the first ultrasound echo signal to obtain at least one frame of ultrasound tissue image of the heart region; set a sampling gate at the first target position of the at least one frame of ultrasound tissue image, and obtain the first spectrum data at the sampling gate of the first target position according to the second ultrasonic echo signal; set the sampling gate at the second target position of the at least one frame of ultrasonic tissue image, and according to the The second ultrasonic echo signal obtains the second spectral data at the sampling gate of the second target position; and the first spectral data and the second spectral data are interactively analyzed to obtain comprehensive spectral information;
  • a display for displaying the integrated spectrum information.
  • a third aspect of the embodiments of the present invention provides an ultrasonic imaging method, the method includes: transmitting a first ultrasonic wave to a plurality of target regions, and receiving ultrasonic echoes respectively returned from the plurality of target regions to obtain a plurality of first ultrasonic waves echo signals; process the plurality of first ultrasonic echo signals to obtain ultrasonic tissue images of each target area; set sampling gates on the ultrasonic tissue images of each target area respectively; The target position transmits a second ultrasonic wave respectively to obtain multiple spectrum images at each sampling gate; obtains multiple sets of spectrum data according to the multiple spectrum images; and performs interactive analysis on the multiple sets of spectrum data to obtain comprehensive spectrum information
  • a fourth aspect of the embodiments of the present invention provides an ultrasonic imaging system, including: an ultrasonic probe, configured to transmit a first ultrasonic wave to a target area before setting a sampling gate, receive an echo of the first ultrasonic wave, and based on the first ultrasonic wave The echo of the ultrasonic wave obtains the first ultrasonic echo signal, and after the sampling gate is set, the second ultrasonic wave is transmitted to at least two target positions where the sampling gate is set, the echo of the second ultrasonic wave is received, and based on the obtaining a second ultrasonic echo signal from the echo of the second ultrasonic wave;
  • the transmit/receive control circuit is used to control the ultrasonic probe to transmit the first ultrasonic wave before the sampling gate is set, and obtain the first ultrasonic echo signal based on the echo of the first ultrasonic wave, and control all the ultrasonic signals after the sampling gate is set.
  • the ultrasonic probe transmits a second ultrasonic wave, and obtains a second ultrasonic echo signal based on the echo of the second ultrasonic wave;
  • a processor configured to process the first ultrasonic echo signal to obtain at least one frame of an ultrasonic tissue image of the target area; the processor is further configured to automatically perform at least one of the following: in the at least one frame A first sampling gate is set at the first target position of the ultrasound tissue image; a second sampling gate is set at the second target position of the at least one frame of ultrasound tissue image; according to the second ultrasound at the first target position obtaining first spectral data at the first sampling gate from an echo signal; and obtaining second spectral data at the second sampling gate according to the second ultrasonic echo signal at the second target position;
  • a fifth aspect of the embodiments of the present invention provides a computer storage medium, on which a computer program is stored, and when the computer program is executed by a computer or a processor, the steps of the above-mentioned ultrasonic imaging method are implemented.
  • the ultrasonic imaging system and method and the computer storage medium according to the embodiments of the present invention can perform automatic and intelligent spectrum analysis on multiple target positions, thereby improving the operation efficiency of doctors.
  • FIG. 1 is a schematic diagram of an ultrasound imaging system according to an embodiment of the present invention.
  • FIG. 2 is a flowchart of an ultrasound imaging method according to an embodiment of the present invention.
  • FIG. 3 is a schematic diagram of a sampling gate position on a cardiac ultrasound image according to an embodiment of the present invention.
  • Fig. 4 is the schematic diagram of the sampling gate frequency spectrum obtained according to the sampling gate B position of Fig. 3;
  • 5a is a schematic diagram of a sampling gate spectral image obtained by scanning the mitral valve orifice according to an embodiment of the present invention
  • 5b is a schematic diagram of a sampling gate spectral image obtained by scanning the valve annulus according to an embodiment of the present invention
  • FIG. 6 is a flowchart of an ultrasonic imaging method according to another embodiment of the present invention.
  • FIG. 1 shows a schematic structural block diagram of an ultrasound imaging system 100 according to an embodiment of the present invention.
  • the ultrasound imaging system 100 includes an ultrasound probe 110 , a transmit circuit 112 , a receive circuit 114 , a beamforming circuit 116 , a processor 118 , a display 120 , a transmit/receive selection switch 122 and a memory 124 .
  • the transmitting circuit 112 and the receiving circuit 114 can be connected to the ultrasonic probe 110 through the transmitting/receiving selection switch 122, and the transmitting circuit 112, the receiving circuit 114 and the transmitting/receiving selection switch 122 can constitute the transmitting/receiving control circuit of the ultrasonic imaging system 100.
  • Ultrasound probe 110 typically includes an array of multiple elements. Every time ultrasonic waves are emitted, all or part of the array elements of the ultrasonic probe 110 participate in the emission of ultrasonic waves. At this time, each array element or each part of the array elements participating in the ultrasonic emission is stimulated by the transmitting pulse and emits ultrasonic waves respectively.
  • the synthetic ultrasound beam of the target object for example, the synthetic ultrasound beam may be ultrasound waves emitted to a target area of the target object (eg, a human body).
  • the transmit circuit 112 transmits the delayed-focused transmit pulse with a certain amplitude and polarity to the ultrasound probe 110 through the transmit/receive selection switch 122 .
  • the ultrasonic probe 110 is excited by the transmission pulse, transmits ultrasonic waves to the target object, receives ultrasonic echoes with information of the target object reflected and/or scattered back from the target area after a certain delay, and reconverts the ultrasonic echoes for electrical signals.
  • the receiving circuit 114 receives the electrical signals converted and generated by the ultrasonic probe 110 , obtains ultrasonic echo signals, and sends the ultrasonic echo signals to the beam forming circuit 116 .
  • the beam forming circuit 116 performs focusing delay, weighting and channel summation on the ultrasonic echo signal, and then sends the ultrasonic echo signal to the processor 118 for related signal processing
  • the processor 118 may process the ultrasound echo signal obtained based on the ultrasound echo to obtain an ultrasound image of the target object.
  • the ultrasound images processed by the processor 118 may be stored in the memory 124 or displayed on the display 120 .
  • Memory 124 may be used to store instructions executed by processor 118 for storing received ultrasound echo signals, for storing ultrasound images, and the like. More detailed descriptions can be found in subsequent embodiments of this specification.
  • the display 120 is connected to the processor 118 , and the display 120 can display the ultrasound image obtained by the processor 118 .
  • the display 120 can also provide a graphical interface for the user to perform human-computer interaction while displaying the ultrasound image, set one or more controlled objects on the graphical interface, and provide the user with a human-computer interaction device to input operating instructions to control these objects.
  • the controlled object so as to perform the corresponding control operation.
  • an icon is displayed on the graphical interface, and the icon can be operated by using a human-computer interaction device to perform a specific function, such as a function of starting the calculation of comprehensive spectrum information.
  • the ultrasound imaging system 100 may also include other human-computer interaction devices other than the display 120 , which are connected to the processor 118 .
  • the human-computer interaction device may include an input device for detecting user input information, for example, the input information may be a control command for ultrasonic transmission/reception timing, an input command for acquiring spectrum information, etc., or may also include other Instruction type.
  • the input device may include one or a combination of a keyboard, a mouse, a scroll wheel, a trackball, a mobile input device (such as a mobile device with a touch display screen, a cell phone, etc.), a multi-function knob, and the like.
  • the human-computer interaction apparatus may also include an output device such as a printer, eg, for printing ultrasound reports.
  • the components included in the ultrasound imaging system 100 shown in FIG. 1 are only illustrative, and may include more or less components. The present invention is not limited to this.
  • the ultrasonic imaging system 100 can obtain the spectral data of at least two target positions in the target area, and can further calculate the comprehensive spectral information according to the spectral data of each target position, and the ultrasonic imaging system 100 can automatically obtain the spectral data and /or to calculate comprehensive spectral information.
  • the ultrasound imaging system 100 of the present invention can significantly reduce the operational complexity of obtaining spectral data and/or integrated spectral information, and improve the user's operational efficiency.
  • the method can obtain spectral data of multiple ( ⁇ 2) target positions, and can obtain comprehensive spectral information based on the spectral data.
  • the ultrasound imaging system 100 described above in connection with FIG. 1 may be used to perform the ultrasound imaging method 200 .
  • the method 200 includes step S201 , transmitting a first ultrasonic wave to a target area, and receiving ultrasonic echoes returned by the target area to obtain a first ultrasonic echo signal.
  • the target region may be a human heart, a fetal heart, a fetal umbilical artery, or other organ tissue.
  • the first ultrasonic wave emitted to the target area is for the purpose of obtaining an ultrasonic tissue image.
  • the transducer of the ultrasonic probe 110 transmits the first ultrasonic wave to the target area, and converts the echo received from the first ultrasonic wave into an electrical signal, that is, obtains the first ultrasonic echo signal.
  • first ultrasonic wave and the “first ultrasonic echo signal” herein are only for mutual comparison with the “second/third ultrasonic wave” and the “second/third ultrasonic echo signal” which will be described later. It is so named to distinguish it without any restrictive meaning.
  • Step S202 processing the first ultrasonic echo signal to obtain at least one frame of ultrasonic tissue image of the target area.
  • the first ultrasonic echo signal obtained in step S201 it may be processed to generate B image data.
  • an ultrasound tissue image may be obtained, eg, multiple frames of ultrasound tissue images may be obtained.
  • Step S203 in response to the spectrum information acquisition instruction, setting sampling gates at the first target position and the second target position of the at least one frame of ultrasound tissue image respectively.
  • the first target position and the second target position may be on the same frame of ultrasound tissue images, or may be on two different frames of ultrasound tissue images.
  • the first target position and the second target position should be understood to refer to two or more target positions, each target position is set with a sampling gate, so two or more sampling gates can be set in step S203.
  • the two or more sampling gates can be on the same frame of ultrasound tissue images or on two different frames of ultrasound tissue images.
  • the ultrasound imaging system may respectively set sampling gates at the first target position and the second target position on a frame of ultrasound tissue image.
  • the first target position and the second target position are respectively determined on a frame of ultrasound tissue image, and then sampling gates are respectively set at the first target position and the second target position.
  • the first sampling gate A can be set at the target position of the mitral valve orifice on a frame of ultrasound tissue image of the heart region, and the A second sampling gate B is set at this other target location at the valve annulus.
  • each target position usually corresponds to different parts, or at most corresponds to partially overlapping parts.
  • the ultrasound imaging system can respectively determine the target position on two or more frames of ultrasound tissue images, so as to complete the setting of the sampling gate. For example, taking the setting of a sampling gate on two frames of ultrasound tissue images as an example, the first target position can be determined on one frame of ultrasound images, the second target position can be determined on the other frame of ultrasound images, and then the two frames of ultrasound tissue images can be used to determine the position of the second target. to complete the sampling gate settings. For example, when measuring cardiac E/E', a first sampling gate can be set at the mitral valve orifice of one frame of ultrasound tissue image of the heart region, and a first sampling gate can be set at the valve annulus of another frame of ultrasound tissue image of the heart region. Two sampling gates.
  • a first sampling gate may be set at the umbilical cord opening of one frame of ultrasound tissue image
  • a second sampling gate may be set at the umbilical cord opening of another frame of ultrasound tissue image.
  • the number of frames of ultrasound tissue images used to set sampling gates can be equal to the number of sampling gates to be set, or greater than 1 and smaller than the sampling gates to be set the number of doors.
  • each target position where the sampling gate is set may correspond to different parts, partially overlapping parts, or even the same part.
  • sampling gates on one frame of ultrasound tissue image as an example, but it should be understood that the identification operation of sampling gates can also be applied to two or more frames of ultrasound tissue unless it is separately explained or emphasized.
  • Set a sampling gate on the image mainly takes the setting of at least two sampling gates on one frame of ultrasound tissue image as an example, but it should be understood that the identification operation of sampling gates can also be applied to two or more frames of ultrasound tissue unless it is separately explained or emphasized.
  • the ultrasound imaging system 100 can automatically identify the sampling gate in response to the spectrum information acquisition instruction.
  • the system can automatically identify multiple (at least two) target parts of a frame of ultrasound tissue image as multiple target positions to set sampling gates, and set sampling gates at the target parts corresponding to each target position.
  • each target part can be identified based on machine learning or deep learning.
  • standard images of the mitral valve orifice and valve annulus can be used to pre-train the ultrasound imaging system. Based on learning from standard images, the system can identify the mitral valve orifice and/or valve annulus in the input image. In one way, automatic identification can be performed according to the image features or motion features of each target part.
  • the valve annulus moves very fast, and it will appear as two bright lines on the ultrasound tissue image. Based on the grayscale difference between the bright line and the surrounding tissue, the ultrasound tissue image can be identified. position of the valve annulus. After the position of the target part is determined, a sampling gate can be set at the target position; the setting of the sampling gate is a conventional technique, and will not be described here.
  • the ultrasonic imaging system after the ultrasonic imaging system automatically sets the sampling gate, it can also receive input from the user to adjust the setting position of the sampling gate, so as to set the sampling gate at the adjusted position.
  • the system can prompt the user whether to adjust the position of the sampling gate after determining the position of a single sampling gate, or whether to adjust the position of the sampling gate after determining the positions of all sampling gates.
  • the system may also not actively provide the sampling door position adjustment prompt, and the user can actively trigger the sampling door position adjustment operation.
  • the ultrasonic imaging system 100 may include a sampling door setting button, and the user can adjust the position of the sampling door that has been set by using the sampling door setting button.
  • the adjusted positions are determined, and sampling gates are set at the adjusted positions respectively. This includes the keys described below, which may be physical keys or some interactive options on the touch screen or display screen, as long as the user can operate and trigger the corresponding sampling door position adjustment operation.
  • the user can input the image range to be recognized on the ultrasound tissue image before the system starts the automatic recognition, thereby reducing the calculation amount of the automatic recognition by the system and improving the overall work efficiency.
  • the user can directly delineate the frame of interest on the ultrasound image, or specify the image recognition range, etc.
  • the user can also start the operation of setting the sampling gate again after the system has output the sampling gate, until the set sampling gate meets the needs of the user.
  • the ultrasound imaging system may use a frame of ultrasound tissue image corresponding to the trigger time of the spectrum information acquisition instruction as the object to be set with the sampling gate.
  • the user will play a video of the acquired ultrasound tissue image of the heart region of the target object.
  • the frame of ultrasound tissue images corresponding to the triggering time of the instruction (the 5th second) is used as the object to be set as the sampling gate. If the system is set to set sampling gates on at least two frames of ultrasound tissue images, after detecting the spectrum information acquisition instruction, in this step, the trigger time of the spectrum information acquisition instruction can be changed to another corresponding to a preset time interval.
  • the frame ultrasound tissue image is also used as the object to be set as the sampling gate; or the user may be prompted to further input another spectrum information acquisition instruction after the spectrum information acquisition instruction, and the ultrasound tissue images corresponding to the trigger times of the two spectrum information acquisition instructions respectively, As the object to set the sampling gate.
  • the ultrasound imaging system 100 may include an imaging mode switching button, when the imaging mode switching button is triggered, it is regarded as a triggering instruction to obtain spectrum information, and correspondingly, a frame of ultrasound tissue image corresponding to the triggering time of the imaging mode switching button is used as the sample to be set. door object.
  • the imaging mode switching button may include a blood flow Doppler imaging button and a tissue Doppler imaging button. When the blood flow Doppler imaging button is triggered, and/or the tissue Doppler imaging button is triggered, it can be regarded as triggering an instruction for acquiring spectral information.
  • the ultrasound imaging system 100 may also include a spectrum information acquisition button. After the spectrum information acquisition button is triggered, a sampling gate is set on the ultrasound tissue image.
  • the spectrum information acquisition button may be a special button that triggers the system to automatically acquire spectrum information; after the spectrum information acquisition button is triggered, the ultrasound imaging system 100 can automatically perform at least one of step S203, steps S204 and S205 below, and can automatically Performing the operation of setting one sampling gate, partial sampling gate or all sampling gates in step S203 can automatically execute the operation of acquiring a group of spectral data, a partial group of spectral data or all groups of spectral data in step S204.
  • the ultrasound imaging system 100 can support the user's pre-setting of the automatic operation of the system. For example, the system defaults to automatically execute steps S203-S205. After the spectrum information acquisition button is triggered, the system can prompt the user to reset the automatic operation content of the system.
  • the ultrasound imaging system may perform temporal smoothing processing on the target position where the sampling gate is set on a frame of ultrasound tissue image. Specifically, at least two frames of ultrasound tissue images may be selected from the multiple frames of ultrasound tissue images, and positions for setting multiple sampling gates may be determined on the selected at least two frames of ultrasound tissue images, and then according to the selected frames of ultrasound tissue images The position of the sampling gate, the target position of the sampling gate is calculated. Taking the measurement of cardiac E/E' as an example, the system can determine the position of the mitral valve orifice on multiple frames of ultrasound tissue images in the heart region, and then perform statistical analysis on the position of the mitral valve orifice on these multiple frames of images. Thereby, the target position of the mitral valve orifice is obtained, and a sampling gate is set at the target position on any selected frame of ultrasound tissue image. The time smoothing process can further improve the setting accuracy of the sampling gate.
  • the ultrasound imaging system may further acquire the ECG signal when measuring the cardiac E/E', and convert a frame of ultrasound tissue images (also referred to as ultrasound) of the cardiac region corresponding to the specified time of the ECG signal.
  • Called cardiac tissue image as the object to be set sampling gate; that is, set sampling gate on a frame of cardiac tissue image corresponding to the specified time of ECG signal.
  • ECG signals can be obtained from monitors, electrocardiographs, or Holter devices.
  • the sampling gate can be set on at least two frames of cardiac tissue images corresponding to the designated timing of the ECG signal.
  • the ultrasound imaging system may further utilize blood flow and tissue motion information to determine the target position for setting the sampling gate based on the tissue information obtained based on the ultrasound tissue image.
  • a third ultrasonic wave can be transmitted to the target area
  • a third ultrasonic echo signal can be obtained according to the echo of the third ultrasonic wave
  • the third ultrasonic echo signal can be processed to obtain Doppler data (including blood flow) of the target area.
  • Doppler data and tissue Doppler data can be processed to obtain Doppler data (including blood flow) of the target area.
  • Doppler data and tissue Doppler data can be processed to obtain Doppler data (including blood flow) of the target area.
  • Doppler data and tissue Doppler data can be processed to obtain Doppler data (including blood flow) of the target area.
  • Doppler data and tissue Doppler data can be processed to obtain Doppler data (including blood flow) of the target area.
  • Doppler data and tissue Doppler data can be processed to obtain Doppler data (including blood
  • fusion analysis can be performed based on the Doppler data of the target area and the ultrasound tissue image data, and the target position for setting the sampling gate can be directly obtained.
  • the position of the sampling gate to be set can be determined according to the Doppler data of the target area, and then the position determined according to the Doppler data can be mapped to the ultrasound tissue image, thereby realizing automatic identification of the target position on the ultrasound tissue image.
  • at least one frame of color velocity images of the target area may be obtained based on Doppler data of the target area (including a color blood flow image obtained from blood flow Doppler data, and a color flow image obtained from tissue Doppler data color tissue images).
  • the ultrasound imaging system may identify at least two positions for setting the sampling gate based on the at least one frame of color velocity image, and then determine the ultrasound tissue according to the position for setting the sampling gate on the at least one frame of the color velocity image. Set the target position of the sampling gate on the image.
  • the type of at least one sampling gate is different from that of the other sampling gates; when at least two sampling gates are set, set at a first target position of the at least two target positions For the first type sampling gate, a second type sampling gate different from the first type sampling gate is arranged at a second target position of the at least two target positions.
  • the different types of sampling gates here may refer to sampling gates used in different imaging modes in some examples, and may have different characteristic information such as sampling gate widths, sampling gate center positions, and the like.
  • a first type sampling gate is set at the position of the mitral valve orifice, specifically a sampling gate for blood flow Doppler imaging is set, and one or two sampling gates are set at the position of the mitral valve orifice.
  • a second type of sampling gate is set at the valve annulus, specifically a sampling gate for tissue Doppler imaging is set.
  • step S204 a second ultrasonic wave is emitted to the first target position and the second target position, and Doppler imaging is performed at the sampling gate of the first target position and the sampling gate of the second target position, respectively, and the first target position is obtained.
  • the ultrasound imaging system 100 can obtain multiple sets of spectral data at each sampling gate synchronously.
  • the second ultrasonic waves can be alternately emitted to the first target position and the second target position, and according to the alternately obtained second ultrasonic echo signals,
  • the first spectral data at the sampling gate at the first target position and the second spectral data at the sampling gate at the second target position are obtained synchronously.
  • the second ultrasonic waves are alternately emitted at the two target positions, so that the ultrasonic imaging system 100 can perform ultrasonic scanning at the two sampling gates at approximately the same time, so as to obtain spectral data at the two sampling gates simultaneously.
  • the ultrasound imaging system 100 may successively obtain multiple sets of spectral data at each sampling gate, that is, first scan to obtain spectral data at one sampling gate, and then scan to obtain spectral data at another sampling gate .
  • the second ultrasonic wave can be firstly transmitted to the first target position, and the first spectral data at the sampling gate of the first target position can be obtained according to the obtained second ultrasonic echo signal.
  • the second ultrasonic wave is transmitted to the second target position, and the second spectrum data at the sampling gate of the second target position is obtained according to the second ultrasonic echo signal obtained at this time.
  • the spectrum data corresponding to the two target positions are obtained in sequence.
  • the spectral data of each target position can be obtained sequentially, or the spectral data of some target positions can be obtained synchronously first, and the spectral data of the remaining target positions can be obtained later. Synchronized acquisition, etc.
  • steps S203 and S204 are not used to limit the execution sequence of the ultrasonic imaging method 200, and the ultrasonic imaging system 100 may be configured after sampling gates have been set at the first target position and the second target position, and then Scanning to obtain multiple sets of spectral data at each sampling gate; it is also possible to set sampling gates at the first target position, perform corresponding scanning to obtain the first spectral data at the sampling gate, and then set sampling at the second target position. gate to scan to obtain second spectral data at the sampling gate.
  • the ultrasonic imaging system 100 may perform alternate ultrasonic scanning on the two target positions after setting two sampling gates to obtain two sampling gates simultaneously.
  • the ultrasonic imaging system 100 may first perform ultrasonic scanning on one target position after setting two sampling gates, and obtain spectral data, and then perform ultrasonic scanning on the other target position; the ultrasonic imaging system 100 also A sampling gate may be set at one of the target positions first, and ultrasonic scanning is performed to obtain corresponding spectral data, and then a sampling gate is set at the other target position to obtain the spectral data at the sampling gate at the other target position.
  • the ultrasound imaging system 100 obtains a spectrum image according to the transmitted second ultrasound, and then processes the spectrum image to obtain spectrum data.
  • the specific technology of Doppler imaging to obtain spectral images is well known in the art, and will not be described in detail in this application.
  • transmitting the second ultrasonic wave to the first target position and the second target position to obtain the first spectral data and the second spectral data respectively includes: transmitting the second ultrasonic wave to the first target position, and scanning the target object to obtain the second ultrasonic wave
  • For the echo signal a first spectral image is obtained based on the second ultrasonic echo signal, and feature value extraction is automatically performed on the first spectral image to obtain first spectral data.
  • FIG. 4 is a schematic diagram of the sampling gate spectrum obtained according to the sampling gate position B of FIG. 3 .
  • the amplitude extraction can be performed directly based on the sampling gate spectrum, or the sampling gate spectrum in FIG. 4 can be further traced. trace processing. All traces can obtain trace results that are more in line with the actual spectrum data, and partial traces can improve the speed of the system to automatically obtain spectrum data.
  • the ultrasound imaging system 100 may receive the user's adjustment of the feature value extraction operation, and obtain the first spectrum data and the second spectrum data according to the adjusted feature value extraction operation. After the system performs the tracing operation, the user can, for example, adjust the position of the tracing line, so as to adjust the feature value (such as the amplitude) obtained later according to the tracing result.
  • step S205 comprehensive spectrum information of the target area is obtained according to the first spectrum data and the second spectrum data.
  • interactive analysis may be performed on the first spectral data and the second spectral data, so as to obtain comprehensive spectral information of the target area.
  • the interactive analysis here refers to comprehensive analysis of the first spectral data and the second spectral data, for example, comprehensive analysis may be performed based on the relationship between each group of spectral data.
  • the obtained comprehensive spectrum information can be further displayed and output, for example, it can be directly displayed on the ultrasound image, and can be displayed separately from the ultrasound image.
  • the first target position is the mitral valve orifice of the heart
  • the first spectral data is the blood flow obtained at the sampling gate of the mitral valve orifice Doppler data.
  • Fig. 5a shows a spectral image obtained by scanning the mitral valve orifice
  • the blood flow Doppler data obtained based on the spectral image includes a first positive peak E and a positive second peak A.
  • the second target position is the valve annulus of the heart
  • the second spectral data is the tissue Doppler data obtained at the sampling gate of the valve annulus (when the sampling gates are set at the two valve annuluses, the tissue Doppler data at the two valve annuluses can be taken Statistical value of Le data, as the second spectral data).
  • Figure 5b shows a spectral image obtained by scanning the valve annulus, and tissue Doppler data obtained based on the spectral image includes a negative first peak E' and a negative second peak A'.
  • the ultrasound imaging system 100 may calculate the ratio of the positive first peak value E to the negative first peak value E', and/or calculate the ratio of the positive first peak value E to the positive second peak value A.
  • the interaction analysis performed by the ultrasound imaging system 100 is a ratio calculation.
  • the ultrasound imaging system 100 can also perform processing other than ratio calculation, such as difference calculation, weighted addition, and weighted multiplication, so as to comprehensively consider the first spectrum data and the second spectrum data to obtain the target area including each target position.
  • processing other than ratio calculation such as difference calculation, weighted addition, and weighted multiplication, so as to comprehensively consider the first spectrum data and the second spectrum data to obtain the target area including each target position.
  • the ultrasonic imaging method may further include the following steps: performing image quality evaluation on the ultrasonic tissue image provided with the sampling gate, and obtaining the spectral data obtained in step S204 according to the image quality evaluation result (the first spectral data and the confidence of the second spectral data).
  • the ultrasound imaging system 100 can analyze attributes of the ultrasound tissue image, such as image clarity, image uniformity, and the like, so as to evaluate the quality of the ultrasound tissue image. The higher the image quality, the more accurately the target location is usually determined, the more accurate the sampling gate setting, and the higher the confidence of the spectral data.
  • the ultrasonic imaging method may further include the following steps: performing a signal-to-noise ratio evaluation on the first spectral data and the second spectral data, and obtaining a confidence level of the first spectral data and a second spectral data according to the signal-to-noise ratio evaluation result. Confidence in spectral data. The higher the signal-to-noise ratio, the higher the confidence in the corresponding spectral data.
  • a threshold for the confidence level of the spectral data may be set inside the ultrasound imaging system 100 . After the confidence level of each group of spectrum data is determined, it can be further judged whether the confidence level of the spectrum data conforms to the valid data range defined by the threshold. If the confidence level of the spectral data does not meet the valid data range defined by the threshold, the user may be prompted which spectral data has a low confidence level.
  • it may report an error directly and not output the corresponding spectrum data and/or integrated spectrum information; it may be to prompt the user spectrum data through color, pattern, sound and/or a combination thereof while outputting the spectrum data and/or integrated spectrum information
  • the confidence is low; it may be outputting the value of the confidence of the spectral data and the reference range of the confidence, etc. at the same time as outputting the spectral data and/or the integrated spectral information.
  • the ultrasound imaging method described above in conjunction with steps S201 to S205 may be automatically performed by the ultrasound imaging system 100 in at least one of the following operations: setting a first sampling gate at the first target position of at least one frame of ultrasound tissue image; A second sampling gate is set at the second target position of at least one frame of ultrasound tissue image; first spectrum data at the first sampling gate is obtained according to the second ultrasound echo signal at the first target position; according to the second target position Obtain second spectrum data at the second sampling gate from the second ultrasonic echo signal; and perform interactive calculation based on the first spectrum data and the second spectrum data to obtain comprehensive spectrum information.
  • the ultrasonic imaging method realizes the operation of setting sampling gates at multiple target positions and the automation of subsequent spectrum analysis, which is more efficient and smarter overall.
  • the ultrasound imaging system 100 can identify the mitral valve orifice as the first target position on at least one frame of ultrasound tissue image of the heart region, A sampling gate (eg, described as a first sampling gate) is placed at the mitral valve orifice, one or more annulus is identified as a second target location, and a sampling gate (eg, described as a second sampling gate) is placed at one or more annulus sampling gate).
  • a sampling gate eg, described as a first sampling gate
  • one or more annulus is identified as a second target location
  • a sampling gate eg, described as a second sampling gate
  • the operations of determining the target position and setting the sampling gate may be performed, at least in part, automatically by the system.
  • the ultrasonic imaging system 100 performs blood flow Doppler imaging at the first sampling gate, transmits a second ultrasonic wave to the mitral valve orifice, and obtains a blood flow Doppler image based on the second ultrasonic echo signal obtained at the mitral valve orifice, The feature value extraction is performed on the blood flow Doppler image to obtain blood flow Doppler data, for example, the first positive peak value on the spectrum image.
  • the ultrasonic imaging system 100 performs tissue Doppler imaging at the second sampling gate, transmits a second ultrasonic wave to one or more valve annuluses, obtains a tissue Doppler image based on the second ultrasonic echo signals obtained at the valve annulus, and conducts tissue Doppler imaging.
  • the Doppler image is subjected to feature value extraction to obtain tissue Doppler data, such as negative peaks on the spectrum image (which can be multiple negative peaks, the first negative peak and the second negative peak described above).
  • tissue Doppler data such as negative peaks on the spectrum image (which can be multiple negative peaks, the first negative peak and the second negative peak described above).
  • the operation of acquiring spectral data can also be performed automatically by the system at least in part.
  • the ultrasound imaging system 100 may calculate the ratio of the positive first peak to the negative first peak, and/or calculate the ratio of the positive first peak to the negative second peak, and use the ratio as the comprehensive spectral information of the heart region.
  • the specific process and deformable manner of each step are the same as the ultrasonic imaging method 200 described above, and the description is not repeated here.
  • the ultrasound imaging system 100 can identify the umbilical cord opening as the first target on one of the ultrasound tissue images in the uterine region including the umbilical cord opening. Position, set a sampling gate at the umbilical cord opening (for example, described as the first sampling gate); the ultrasound imaging system 100 sets another sampling gate at the umbilical cord opening on another frame of the ultrasound tissue image in the uterine region that includes the umbilical cord opening (eg described as second sampling gate).
  • the operations of determining the target position and setting the sampling gate may be performed, at least in part, automatically by the system.
  • the ultrasound imaging system 100 performs blood flow Doppler imaging at the first sampling gate and the second sampling gate respectively, transmits a second ultrasonic wave to the umbilical cord opening, and obtains blood flow Doppler based on the second ultrasonic echo signal obtained at the umbilical cord opening. image, extract the characteristic value of the blood flow Doppler image, and obtain two groups of blood flow Doppler data.
  • the operation of acquiring spectral data can also be performed automatically by the system at least in part.
  • the ultrasound imaging system 100 may calculate the ratio of the positive first peak value to the negative first peak value, and use the ratio as the comprehensive spectral information of the umbilical cord blood flow in the uterine region.
  • the specific process and deformable manner of each step are the same as the ultrasonic imaging method 200 described above, and the description is not repeated here.
  • the imaging method that can be performed by the ultrasonic imaging system 100 in the present application mainly includes the following steps: setting a first sampling gate at the first target position of at least one frame of ultrasonic tissue image; A second sampling gate is set at the second target position; the first spectrum data at the first sampling gate is obtained according to the second ultrasonic echo signal at the first target position; the first spectral data at the first sampling gate is obtained according to the second ultrasonic echo signal at the second target position second spectrum data at the second sampling gate; and performing interactive calculation based on the first spectrum data and the second spectrum data to obtain comprehensive spectrum information.
  • the ultrasound imaging system 100 can automatically perform at least one of the above steps.
  • the ultrasound imaging system may automatically set only the first sampling gate, may only automatically acquire the first spectrum data and the second spectrum data, may automatically set the first sampling gate and automatically obtain the first spectrum data, and the like.
  • the sampling gate can be automatically set only at the valve annulus and the corresponding spectral data can be automatically obtained, while the user can manually set the sampling gate at the mitral valve orifice and manually obtain the spectrum at the mitral valve orifice.
  • Data manipulation; only the spectral data at the mitral valve orifice and annulus can be obtained automatically, but the operation of manually setting the sampling gate by the user is retained; the sampling gate at the mitral valve orifice and the annulus can also be automatically set and the corresponding spectrum can be obtained data.
  • the ultrasound imaging system may automatically obtain only the integrated spectrum information, may automatically obtain the first spectrum data and the second spectrum data, and automatically obtain the integrated spectrum information based on the first spectrum data and the second spectrum data.
  • the comprehensive spectral information of the mitral valve orifice and the valve annulus can be automatically calculated only after obtaining the spectral data at the valve annulus and the mitral valve orifice; it can also be obtained automatically separately.
  • the spectral data at the mitral valve orifice and the spectral data at the valve annulus are automatically calculated to obtain comprehensive spectral information based on the spectral data of the two target sites.
  • the present application may further provide a modification of the ultrasonic imaging method of FIG. 2 , setting the imaging object of the ultrasonic imaging method as multiple (at least two) target regions.
  • the ultrasound imaging method 600 may specifically include the following steps S601 to S605.
  • step S601 first ultrasonic waves are respectively transmitted to multiple target areas, and ultrasonic echoes returned respectively from the multiple target areas are received to obtain multiple first ultrasonic echo signals.
  • the multiple target regions may be selected from human heart, fetal heart, fetal umbilical artery or other organ tissues; the first ultrasonic wave transmitted to the multiple target regions is also aimed at obtaining ultrasound tissue images.
  • step S602 the multiple first ultrasound echo signals are processed to obtain ultrasound tissue images of each target area.
  • the first ultrasonic echo signal obtained in step S601 may be subjected to beamforming, envelope solution and other processing, so as to obtain an ultrasonic tissue image.
  • sampling gates are respectively set on the ultrasound tissue images of each target area.
  • the target position on each ultrasonic tissue image is also determined first, and then sampling gates are set at each target position.
  • the ultrasound tissue image used to set the sampling gate for each target region may be one frame or multiple frames. On a frame of ultrasound tissue image, one sampling gate or multiple sampling gates can be set.
  • statistical processing may be performed on the acquired spectral data in the subsequent steps, for example, the mean value and the median value of the spectral data are obtained.
  • the ultrasound imaging system 100 can automatically set the sampling gate.
  • the system can automatically identify the target part on a frame of ultrasound tissue image as the target position of the sampling gate to be set, and set the sampling gate at the target part corresponding to each target position.
  • each target part can be identified based on machine learning or deep learning.
  • automatic identification can be performed according to the image features or motion features of each target part.
  • a sampling gate can be set at the target position; the setting process of the sampling gate is a conventional technique, and will not be described here. Similar to the method 200, the user can adjust the setting position of the automatically set sampling gate, and can input the image range of the target position to be identified, and so on.
  • step S604 the second ultrasonic waves are respectively emitted to the target positions of the sampling gates to obtain a plurality of spectral images at the sampling gates.
  • the Doppler imaging process known in the art, which will not be described in detail here.
  • multiple sets of spectrum data are further obtained according to multiple spectrum images.
  • feature value extraction may be performed on each spectral image, so as to obtain one or more feature values corresponding to each spectral image, as a set of spectral data corresponding to each spectral image.
  • feature value extraction can be performed by tracing processing or amplitude value extraction. It should be understood that the above steps S603 to S604 do not limit the execution sequence of the ultrasonic imaging method.
  • multiple sampling gates may be set first, and then the second ultrasonic waves are alternately emitted to each sampling gate, so as to obtain multiple spectral images and further sets of spectral data simultaneously.
  • the second ultrasonic wave can be firstly transmitted to one sampling gate to obtain a spectral image and corresponding spectral data can be obtained by calculation, and then the second ultrasonic wave can be transmitted to another sampling gate. , to obtain the spectral image and corresponding spectral data at another sampling gate, and so on.
  • a sampling gate may be set at one target position, the sampling gate at the position transmits ultrasonic waves, and a spectral image and corresponding spectral data are obtained, and then a sampling gate is set at another target position, and the sampling gate at the position is then set to transmit ultrasonic waves to obtain a spectral image and corresponding spectral data. Ultrasonic waves are emitted, and spectral images and corresponding spectral data are obtained.
  • step S605 interactive analysis is performed on multiple sets of spectrum data to obtain comprehensive spectrum information.
  • the interactive analysis here refers to comprehensive analysis of the first spectral data and the second spectral data, for example, comprehensive analysis may be performed based on the relationship between each group of spectral data.
  • step S604 one or more eigenvalues of multiple sets of spectrum data can be obtained respectively, and interactive calculation is performed between the eigenvalues of multiple sets of spectrum data, and the calculation result is the comprehensive spectrum information.
  • At least two sets of spectrum data may be selected from the multiple sets of spectrum data, and then one or more eigenvalues of the selected set of spectrum data may be taken, and interactive calculation may be performed based on the eigenvalues of the selected set.
  • the obtained comprehensive spectrum information can be further displayed and output, for example, it can be directly displayed on the ultrasound image, or it can be displayed separately from the ultrasound image.
  • the ultrasonic imaging system 100 of the present invention can perform the above-mentioned ultrasonic imaging methods 200 and 600 to obtain spectral data of at least two target positions, and obtain comprehensive spectral information based on multiple spectral data. It includes an ultrasonic probe 110 , a transmitting circuit 112 , a receiving circuit 114 , a beam forming circuit 116 , a processor 118 , a display 120 , a transmit/receive selection switch 122 and a memory 124 .
  • the ultrasound probe 110 of the ultrasound imaging system 100 can be used to transmit the first ultrasound to the target area and obtain the first ultrasound echo signal based on the echo of the first ultrasound, so that the ultrasound imaging system can obtain ultrasound tissue images subsequently .
  • the ultrasound probe 110 may transmit the first ultrasound to the heart region, receive the echo of the first ultrasound returned from the heart region, and obtain the first ultrasound echo signal based on the echo of the first ultrasound.
  • the ultrasound probe 110 of the ultrasound imaging system 100 can be used to transmit the second ultrasound to the target area and obtain the second ultrasound echo signal based on the echo of the second ultrasound, so that the ultrasound imaging system can obtain spectral data subsequently.
  • the ultrasonic probe 100 can transmit a second ultrasonic wave to the first target position and the second target position where the sampling gate is set, respectively, receive the echo returned at the set position of the sampling gate, and obtain the echo based on the echo. a plurality of second ultrasonic echo signals.
  • the transmit/receive control circuit of the ultrasound imaging system 100 can be used to control the ultrasound probe 100 to transmit the ultrasound probe 110 to transmit ultrasound (first ultrasound and second ultrasound) and receive echoes of the ultrasound to obtain the second ultrasound echo Signal.
  • the processor 118 of the ultrasound imaging system 100 may be configured to process the first ultrasound echo signal to obtain at least one frame of ultrasound tissue image, which may be at the first target location and the second frame of the at least one frame of ultrasound tissue image.
  • Sampling gates are respectively set at the target positions, and multiple spectrum data are obtained based on the second ultrasonic echo signals at the multiple sampling gates, and comprehensive spectrum information can be obtained by interactive analysis of the multiple spectrum data.
  • the processor 118 may process the first ultrasound echo signal of the heart region to obtain at least one frame of ultrasound tissue image of the heart region.
  • the processor 118 may set a first sampling gate at the mitral valve orifice of at least one frame of ultrasound tissue image of the heart region for performing blood flow Doppler imaging, and set a first sampling gate at the valve annulus of at least one frame of ultrasound tissue image of the heart region. Two sampling gates are used for tissue Doppler imaging, the first spectral data at the first sampling gate is obtained according to the second ultrasonic echo signal at the mitral valve orifice, and the second spectral data is obtained according to the second ultrasonic echo signal at the valve annulus. The second spectral data at the sampling gate.
  • the processor 118 may interactively analyze the first spectrum data and the second spectrum data to obtain comprehensive spectrum information.
  • the processor 118 of the ultrasound imaging system 100 may automatically set at least one of the first sampling gate and the second sampling gate. For example, the processor 118 may automatically set the first sampling gate at the mitral valve orifice alone, the processor 118 may automatically set the second sampling gate at the valve annulus alone, and the processor 118 may also automatically set the mitral valve orifice and the annulus The sampling gate is automatically set.
  • the processor 118 of the ultrasound imaging system 100 may obtain the first spectral data and the second spectral data from the second ultrasound echo signal. For example, the processor 118 may obtain a blood flow Doppler image based on the second ultrasonic echo signal obtained at the mitral valve orifice, and perform feature value extraction on the blood flow Doppler image to obtain blood flow Doppler data. The processor 118 obtains a tissue Doppler image based on the second ultrasonic echo signal obtained at the valve annulus, and performs feature value extraction on the tissue Doppler image to obtain tissue Doppler data.
  • the processor 118 of the ultrasound imaging system 100 may automatically perform feature value extraction on at least one of the blood flow Doppler image and the tissue Doppler image. For example, taking the E/E' measurement of the heart as an example, the processor 118 can automatically perform feature value extraction on the tissue Doppler image obtained at the valve annulus; Extraction of eigenvalues is automatically performed on the ler image; the processor 118 can automatically perform eigenvalue extraction on the tissue Doppler image at the valve annulus and the blood flow Doppler image obtained at the mitral valve orifice. The characteristic value extraction is performed on the blood flow Doppler image at the mitral valve orifice, and the blood flow Doppler data can be obtained, and the blood flow Doppler data includes the positive first peak value.
  • Extracting the characteristic value of the tissue Doppler image at the valve annulus can obtain tissue Doppler data, which can expand the negative first peak value and the negative second peak value.
  • the subsequent processor 118 can calculate the ratio of the positive first peak and the negative first peak to obtain comprehensive spectrum information; it can also calculate the ratio of the positive first peak to the negative second peak to obtain a comprehensive spectrum of another dimension. information.
  • the processor 118 of the ultrasound imaging system 100 can control the ultrasound probe to the mitral valve orifice and the valve annulus through the transmit/receive control circuit after sampling gates have been set at the mitral valve orifice and the valve annulus, respectively.
  • the second ultrasonic waves are alternately emitted, thereby simultaneously acquiring the first spectral data at the mitral valve orifice and the second spectral data at the valve annulus.
  • the processor 118 of the ultrasound imaging system 100 can control the ultrasound probe to transmit the second ultrasound to the mitral valve orifice through the transmit/receive control circuit, and the processor 118 obtains the first spectral data at the mitral valve orifice Afterwards, the ultrasonic probe is controlled to transmit the second ultrasonic wave to the valve annulus through the transmit/receive control circuit, so as to obtain the second spectrum data at the valve annulus.
  • the ultrasound imaging system 100 can support both synchronous acquisition of spectrum data of multiple target positions, or acquisition of spectrum data of multiple target positions sequentially.
  • the ultrasound imaging system 100 may be configured with a button for triggering acquisition of spectrum information.
  • the button may be a specially set button for starting acquisition of spectrum information, or may be one or more imaging mode switching buttons.
  • the imaging mode switching button allows the user to further select whether to start the acquisition of spectrum information.
  • the ultrasound imaging system 100 first acquires at least one frame of ultrasound tissue image of the heart region, and when switching from the tissue grayscale imaging mode to blood flow Doppler imaging or tissue Doppler imaging , the acquisition of spectrum information can be further selected to trigger, and a frame of ultrasound image corresponding to the time when the imaging mode switching button is triggered can be used as the ultrasound tissue image to be set with the sampling gate.
  • the ECG signal can be acquired, and one or more frames of ultrasound tissue images corresponding to the specified time period of the ECG signal can be used as the ultrasound tissue images for which the sampling gate is to be set.
  • the ultrasound imaging system 100 may also determine the ultrasound tissue image for setting the sampling gate based on other means described in the method 200 .
  • a storage medium is also provided, and program instructions are stored on the storage medium, and the program instructions are used for execution when the program instructions are run by a computer or a processor (such as the aforementioned processor 118 ).
  • the storage medium may include, for example, a memory card for a smartphone, a storage unit for a tablet computer, a hard disk for a personal computer, read only memory (ROM), erasable programmable read only memory (EPROM), portable compact disk read only memory (CD-ROM), USB memory, or any combination of the above storage media.
  • the computer-readable storage medium can be any combination of one or more computer-readable storage media.
  • a computer program is also provided, and the computer program can be stored in the cloud or on a local storage medium.
  • the computer program is run by a computer or a processor, it is used to execute the corresponding steps of the ultrasonic image analysis method of the embodiments of the present application.
  • the ultrasonic imaging method, ultrasonic imaging system, and computer storage medium automatically perform at least one of setting sampling gates, acquiring spectral data, and calculating comprehensive spectral information.
  • the automated operation mode can be very good. It can greatly reduce the workload of comprehensive spectrum analysis, so that ultrasonic diagnosis can better meet the clinical needs.
  • the disclosed apparatus and method may be implemented in other manners.
  • the device embodiments described above are only illustrative.
  • the division of the units is only a logical function division. In actual implementation, there may be other division methods.
  • multiple units or components may be combined or May be integrated into another device, or some features may be omitted, or not implemented.
  • Various component embodiments of the present application may be implemented in hardware, or in software modules running on one or more processors, or in a combination thereof.
  • a microprocessor or a digital signal processor (DSP) may be used in practice to implement some or all functions of some modules according to the embodiments of the present application.
  • the application may also be implemented as a program of apparatus (eg, computer programs and computer program products) for performing part or all of the methods described herein.
  • Such a program implementing the present application may be stored on a computer-readable medium, or may be in the form of one or more signals. Such signals may be downloaded from Internet sites, or provided on carrier signals, or in any other form.

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Abstract

一种超声成像方法，该方法包括：向目标区域发射第一超声波，并接收自目标区域返回的超声回波，获得第一超声回波信号；对第一超声回波信号进行处理得到目标区域的至少一帧超声组织图像；响应于频谱信息获取指令，在至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门；向第一目标位置和第二目标位置发射第二超声波，以分别获得第一目标位置的取样门处的第一频谱数据和第二目标位置的取样门处的第二频谱数据；以及根据第一频谱数据和第二频谱数据获得目标区域的综合频谱信息。

Description

超声成像系统、方法和计算机存储介质 技术领域
本申请涉及超声成像技术领域，更具体地涉及一种超声成像系统、方法和计算机存储介质。
 背景技术
现代医学影像检查中，超声技术因其高可靠性、快速便捷、实时成像以及可重复检查等优点，已经成为应用最广、使用频率最高同时新技术普及应用最快的检查手段之一。新的超声技术的发展，进一步推动了超声影像检查在临床诊疗中的应用。
心脏舒张功能评估时，超声成像所获得的E/E’、E/A等是重要的评估指标。现有的操作方法中，医生需要手动操作进入脉冲多普勒成像模式（PW模式），选择取样门位置和在频谱上进行特征位置计算，获得二尖瓣血流的舒张早期峰值E和舒张晚期峰值A；然后再进入组织多普勒成像模式（Tissue Doppler Imaging，TDI模式），再次选择取样门位置和在频谱位置上进行特征位置计算，获得瓣环肌肉的舒张早期峰值E’和舒张晚期峰值A’。整个操作过程步骤繁多，影响医生的工作效率。
 技术解决方案
本发明实施例第一方面提供了一种超声成像方法，该方法包括：
向目标区域发射第一超声波，并接收自所述目标区域返回的超声回波，获得第一超声回波信号；对所述第一超声回波信号进行处理得到所述目标区域的至少一帧超声组织图像；响应于频谱信息获取指令，在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门；向所述第一目标位置和第二目标位置发射第二超声波，以分别获得所述第一目标位置的取样门处的第一频谱数据和所述第二目标位置的取样门处的第二频谱数据；以及根据所述第一频谱数据和第二频谱数据获得所述目标区域的综合频谱信息。
本发明实施例第二方面提供一种超声成像系统，该系统包括：
超声探头，用于在取样门设置前向心脏区域发射第一超声波、接收所述第一超声波的回波、并基于所述第一超声波的回波获取第一超声回波信号，在所述取样门设置后向设置有所述取样门的第一目标位置和第二目标位置发射第二超声波、接收所述第二超声波的回波、并基于所述第二超声波的回波获取第二超声回波信号；
发射/接收控制电路，用于在取样门设置前控制所述超声探头发射第一超声波、并基于所述第一超声波的回波获取第一超声回波信号，在所述取样门设置后控制所述超声探头发射第二超声波、并基于所述第二超声波的回波获取第二超声回波信号；
处理器，用于：对所述第一超声回波信号进行处理得到所述心脏区域的至少一帧超声组织图像；在所述至少一帧超声组织图像的所述第一目标位置设置取样门，并根据所述第二超声回波信号获得所述第一目标位置的取样门处的第一频谱数据；在所述至少一帧超声组织图像的所述第二目标位置设置取样门，并根据所述第二超声回波信号获得所述第二目标位置的取样门处的第二频谱数据；以及对所述第一频谱数据和第二频谱数据进行交互分析得到综合频谱信息；
显示器，用于显示所述综合频谱信息。
本发明实施例第三方面提供一种超声成像方法，该方法包括：向多个目标区域发射第一超声波，并接收自所述多个目标区域分别返回的超声回波，获得多个第一超声回波信号；对所述多个第一超声回波信号进行处理得到各个目标区域的超声组织图像；在所述各个目标区域的超声组织图像上分别设置取样门；以及向所述各个取样门的目标位置分别发射第二超声波，以获得各个取样门处的多个频谱图像；根据所述多个频谱图像获得多组频谱数据；以及对所述多组频谱数据进行交互分析，得到综合频谱信息
本发明实施例第四方面提供一种超声成像系统，包括：超声探头，用于在取样门设置前向目标区域发射第一超声波、接收所述第一超声波的回波、并基于所述第一超声波的回波获取第一超声回波信号，在所述取样门设置后向设置有所述取样门的至少两个目标位置发射第二超声波、接收所述第二超声波的回波、并基于所述第二超声波的回波获取第二超声回波信号；
发射/接收控制电路，用于在取样门设置前控制所述超声探头发射第一超声波、并基于所述第一超声波的回波获取第一超声回波信号，在所述取样门设置后控制所述超声探头发射第二超声波、并基于所述第二超声波的回波获取第二超声回波信号；
处理器，用于对所述第一超声回波信号进行处理得到所述目标区域的至少一帧超声组织图像；所述处理器还用于自动执行以下的至少一项：在所述至少一帧超声组织图像的第一目标位置处设置第一取样门；在所述至少一帧超声组织图像的第二目标位置处设置第二取样门；根据所述第一目标位置处的所述第二超声回波信号获得所述第一取样门处的第一频谱数据；以及根据所述第二目标位置处的所述第二超声回波信号获得所述第二取样门处的第二频谱数据；
显示器，用于显示设置有第一取样门和/或第二取样门的超声组织图像。
本发明实施例第五方面提供一种计算机存储介质，其上存储有计算机程序，所述计算机程序被计算机或处理器执行时实现上述超声成像方法的步骤。
 有益效果
根据本发明实施例的超声成像系统及方法、和计算机存储介质可以对多目标位置进行自动和智能化的频谱分析，提高医生的操作效率。
 附图说明
为了更清楚地说明本发明实施例中的技术方案，下面将对实施例描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本发明的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动性的前提下，还可以根据这些附图获得其他的附图。
在附图中：
图1是本发明一实施例的超声成像系统的示意图；
图2是本发明一实施例的超声成像方法的流程图；
图3是本发明一实施例中心脏超声图像上取样门位置的示意图；
图4是根据图3的取样门B位置得到的取样门频谱的示意图；
图5a是根据本发明一实施例中对二尖瓣口进行扫描得到的取样门频谱图像的示意图；
图5b是根据本发明一实施例中对瓣环处进行扫描得到的取样门频谱图像的示意图；
图6是本发明另一实施例的超声成像方法的流程图。
 本发明的实施方式
为了使得本发明的目的、技术方案和优点更为明显，下面将参照附图详细描述根据本发明的示例实施例。显然，所描述的实施例仅仅是本发明的一部分实施例，而不是本发明的全部实施例，应理解，本发明不受这里描述的示例实施例的限制。基于本发明中描述的本发明实施例，本领域技术人员在没有付出创造性劳动的情况下所得到的所有其它实施例都应落入本发明的保护范围之内。
下面，首先参考图1描述根据本发明一个实施例的超声成像系统，图1示出了根据本发明实施例的超声成像系统100的示意性结构框图。
如图1所示，超声成像系统100包括超声探头110、发射电路112、接收电路114、波束合成电路116、处理器118、显示器120、发射/接收选择开关122以及存储器124。其中，发射电路112和接收电路114可以通过发射/接收选择开关122与超声探头110连接，发射电路112、接收电路114和发射/接收选择开关122可组成超声成像系统100的发射/接收控制电路。
超声探头110通常包括多个阵元的阵列。在每次发射超声波时，超声探头110的所有阵元或者部分阵元参与超声波的发射。此时，这些参与超声波发射的阵元中的每个阵元或者每部分阵元分别受到发射脉冲的激励并分别发射超声波，这些阵元分别发射的超声波在传播过程中发生叠加，形成被发射到目标对象的合成超声波束，例如，该合成超声波束可以为向目标对象（例如人体）的目标区域发射的超声波。
在超声成像过程中，发射电路112将经过延迟聚焦的具有一定幅度和极性的发射脉冲通过发射/接收选择开关122发送到超声探头110。超声探头110受发射脉冲的激励，向目标对象发射超声波，经一定延时后接收从目标区域反射和/或散射回来的带有目标对象的信息的超声回波，并将此超声回波重新转换为电信号。接收电路114接收超声探头110转换生成的电信号，获得超声回波信号，并将这些超声回波信号送入波束合成电路116。波束合成电路116对超声回波信号进行聚焦延时、加权和通道求和等处理，然后将超声回波信号送入处理器118进行相关的信号处理
处理器118可以对基于超声回波得到的超声回波信号进行处理，得到目标对象的超声图像。处理器118处理得到的超声图像可以存储于存储器124中，也可以在显示器120上显示。存储器124可以用于存储处理器118执行的指令，用于存储接收到的超声回波信号，用于存储超声图像，等等。更详细的描述可以参见本说明书的后续实施例。
显示器120与处理器118连接，显示器120可以显示处理器118得到的超声图像。此外，显示器120在显示超声图像的同时还可以提供给用户进行人机交互的图形界面，在图形界面上设置一个或多个被控对象，提供给用户利用人机交互装置输入操作指令来控制这些被控对象，从而执行相应的控制操作。例如，图形界面上显示图标，利用人机交互装置可以对该图标进行操作，用来执行特定的功能，例如启动综合频谱信息计算的功能。
可选地，超声成像系统100还可以包括显示器120之外的其他人机交互装置，其与处理器118连接。其中，人机交互装置可以包括输入设备，用于检测用户的输入信息，该输入信息比如可以是对超声波发射/接收时序的控制指令，可以是获取频谱信息等的输入指令，或者还可以包括其他指令类型。输入设备可以包括键盘、鼠标、滚轮、轨迹球、移动式输入设备（比如带触摸显示屏的移动设备、手机等等）、多功能旋钮等等其中之一或者多个的结合。人机交互装置还可以包括诸如打印机之类的输出设备，例如以用于打印超声报告。
应理解，图1所示的超声成像系统100所包括的部件只是示意性的，其可以包括更多或更少的部件。本发明对此不限定。
本发明的实施例中，超声成像系统100可以获得目标区域内至少两个目标位置的频谱数据，可进一步根据各个目标位置的频谱数据计算综合频谱信息，且超声成像系统100可自动获得频谱数据和/或计算综合频谱信息。通过至少部分操作的自动化，本发明的超声成像系统100可以显著降低获得频谱数据和/或综合频谱信息的操作繁杂度，提高用户的操作效率。
下面，将参考图2描述根据本发明实施例的一种超声成像方法200，该方法可以获得多个（≥2个）目标位置的频谱数据，并可基于这些频谱数据得到综合频谱信息。上述结合图1描述的超声成像系统100可以用于执行超声成像方法200。
该方法200包括步骤S201，向目标区域发射第一超声波，并接收目标区域返回的超声回波，获得第一超声回波信号。示例性地，目标区域可以是人体心脏、胎儿心脏、胎儿脐动脉或其他器官组织。在本申请的实施例中，向目标区域发射的第一超声波是以获得超声组织图像为目的。超声探头110的换能器向目标区域发射第一超声波，并将接收到第一超声波的回波变换为电信号，即获取第一超声回波信号。应注意，本文中的 “第一超声波”以及“第一超声回波信号”仅是为了与下文中将描述的 “第二/第三超声波”以及“第二/第三超声回波信号”彼此区分而如此命名，并无任何限制性意义。
步骤S202，对第一超声回波信号进行处理得到目标区域的至少一帧超声组织图像。在本申请的实施例中，基于步骤S201获取的第一超声回波信号，可以对其进行处理以生成B图像数据。基于生成的B图像数据，可以获得超声组织图像，例如可以获得多帧超声组织图像。
步骤S203，响应于频谱信息获取指令，在至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门。第一目标位置和第二目标位置可以在同一帧超声组织图像上，也可以在两帧不同的超声组织图像上。这里的第一目标位置和第二目标位置应理解为指两个或更多个目标位置，每一目标位置分别设置一个取样门，因此步骤S203中可设置得到两个或更多个取样门。两个或更多个取样门可以在同一帧超声组织图像上，也可以在两帧不同的超声组织图像上。
在本申请的一些实施例中，超声成像系统可以在一帧超声组织图像上，在第一目标位置和第二目标位置分别设置取样门。例如，在一帧超声组织图像上分别确定第一目标位置和第二目标位置，进而在第一目标位置和第二目标位置分别设置取样门。例如，如图3所示，进行心脏E/E’的测量时，可以在一帧心脏区域的超声组织图像上，既在二尖瓣口处这一目标位置设置第一取样门A，也在瓣环处这另一目标位置设置第二取样门B。在同一帧超声组织图像上设置至少两个取样门时，各个目标位置通常对应于不同部位，或至多对应于部分重合的部位。
在本申请的一些实施例中，超声成像系统可以在两帧或更多帧超声组织图像上分别确定目标位置，从而完成取样门的设置。例如，以在两帧超声组织图像上设置取样门为例，可在其中一帧超声图像上确定第一目标位置，在另一帧超声图像上确定第二目标位置，进而在两帧超声组织图像上完成取样门的设置。例如，进行心脏E/E’的测量时，可以在一帧心脏区域的超声组织图像的二尖瓣口处设置第一取样门，在另一帧心脏区域的超声组织图像的瓣环处设置第二取样门。例如，进行脐带血S/D值测量时，可以在一帧超声组织图像的脐带口处设置第一取样门，在另一帧超声组织图像的脐带口处设置第二取样门。在两帧或更多帧超声组织图像上设置取样门时，用来设置取样门的超声组织图像的帧数可以与待设置的取样门的个数相等，也可以大于1且小于待设置的取样门的个数。在两帧或更多帧超声组织图像上设置取样门时，设置取样门的各个目标位置可以对应于不同部分、部分重叠的部位、甚至是相同的部位。
下文主要以在一帧超声组织图像上设置至少两个取样门为例进行说明，但应该理解，若非单独说明或专门强调，取样门的识别操作同样可适用于在两帧或更多帧超声组织图像上设置取样门。
该步骤中超声成像系统100可响应于频谱信息获取指令，自动识别取样门。系统可自动识别出一帧超声组织图像的多个（至少两个）目标部位，作为待设置取样门的多个目标位置，在各个目标位置对应的目标部位处分别设置取样门。一种方式下，可基于机器学习或深度学习的方法识别各个目标部位。以心脏E/E’的测量为例，可使用二尖瓣口、瓣环的标准图像，预先对超声成像系统进行模型训练。系统基于对标准图像的学习，可识别出输入图像中的二尖瓣口和/或瓣环。一种方式下，可根据各目标部位的图像特征或运动特征进行自动识别。同样以心脏E/E’测量为例，瓣环的运动速度非常快，在超声组织图像上会呈现为两条亮线，可基于该亮线与周围组织的灰度差异，识别出超声组织图像中的瓣环位置。目标部位的位置确定后，则可在目标位置处设置取样门；取样门的设置为常规技术，在此不再展开描述。
在一些变形方案中，超声成像系统自动设置取样门后，还可接收用户的输入，对取样门的设置位置进行调整，从而在调整后的位置处设置取样门。系统可以在确定单个取样门的位置后即提示用户是否要调整取样门的位置，也可以是在确定所有取样门的位置后再提示用户是否要调整取样门的位置。系统也可以不主动提供取样门位置调整提示，由用户主动触发取样门的位置调整操作。例如，超声成像系统100可包括取样门设置按键，用户可通过取样门设置按键对已设置的取样门的位置进行调整，超声成像系统100的处理器在接收到用户对取样门位置的调整后，会确定调整后的位置，并在调整后的位置处分别设置取样门。这里包括下文所描述的按键，既可以是物理按键，也可以是触摸屏或显示屏上的一些交互选项，只要用户可以操作并触发对应的取样门位置调整操作即可。
在一些变形方案中，用户可以在系统启动自动识别前，在超声组织图像上输入待识别的图像范围，从而降低系统自动识别的计算量，提高整体工作效率。用户可以在超声图像上直接划定感兴趣框，也可以是指定图像识别范围等。当然，用户还可以在系统已经输出取样门后再次启动设置取样门的操作，直到设置的取样门符合用户的需求。
在一些实施例中，超声成像系统可将与频谱信息获取指令的触发时间对应的一帧超声组织图像，作为待设置取样门的对象。以心脏E/E’的测量为例，用户会播放所获取的目标对象的一段心脏区域的超声组织图像的视频，系统检测到用户触发频谱信息获取指令时（如第5秒），则将该视频的多帧超声组织图像中，与该指令的触发时间对应（第5秒）的那一帧超声组织图像，作为待设置取样门的对象。若系统设定为在至少两帧超声组织图像上设置取样门，则该步骤在检测到频谱信息获取指令后，可以将频谱信息获取指令的触发时间后，一预设时间间隔所对应的另一帧超声组织图像也作为待设置取样门的对象；或可以在频谱信息获取指令后还提示用户进一步输入另一频谱信息获取指令，将两次频谱信息获取指令的触发时间分别对应的超声组织图像，作为待设置取样门的对象。
超声成像系统100可包括成像模式切换按键，在成像模式切换按键被触发时，视为触发频谱信息获取指令，对应地，与成像模式切换按键的触发时间对应的一帧超声组织图像作为待设置取样门的对象。例如，成像模式切换按键可以包括血流多普勒成像按键和组织多普勒成像按键。血流多普勒成像按键被触发，和/或组织多普勒成像按键被触发时，可视为触发频谱信息获取指令。替代性地，超声成像系统100也可包括一频谱信息获取按键，该频谱信息获取按键被触发后，则在超声组织图像上设置取样门。该频谱信息获取按键可以是触发系统自动获取频谱信息的专设按键；频谱信息获取按键被触发后，超声成像系统100可以自动执行步骤S203、下文的步骤S204和步骤S205的至少一个步骤，可以自动执行步骤S203中设置一个取样门、部分取样门或全部取样门的操作，可以自动执行步骤S204中获取一组频谱数据、部分组频谱数据或所有组频谱数据的操作。超声成像系统100可支持用户对系统自动执行操作的预先设定，例如系统默认为自动执行步骤S203-S205，频谱信息获取按键被触发后，系统可提示用户对系统自动化操作内容进行重新设定。
在一些实施例中，超声成像系统可以对一帧超声组织图像上设置取样门的目标位置进行时间平滑处理。具体地，可从多帧超声组织图像选择至少两帧超声组织图像，在选择的至少两帧超声组织图像上分别确定多个设置取样门的位置，随后再根据所选择的各帧超声组织图像上取样门的位置，计算出取样门的目标位置。以心脏E/E’的测量为例，系统可在心脏区域的多帧超声组织图像上，分别确定二尖瓣口的位置，再对这些多帧图像上二尖瓣口的位置进行统计分析，从而得出二尖瓣口的目标位置，并在所选择的任一帧超声组织图像上的该目标位置处设置取样门。该时间平滑处理可以进一步提高取样门的设置准确性。
在一些实施例中，超声成像系统在进行心脏E/E’的测量时，可以进一步获取心电信号，并将与心电信号的指定时相相对应的一帧心脏区域的超声组织图像（也称为心脏组织图像），作为待设置取样门的对象；即，在与心电信号的指定时相相对应的一帧心脏组织图像上设置取样门。心电信号可以获取自监护仪、心电图机或Holter设备。系统设定为在两帧超声组织图像上设置取样门时，则可在与心电信号的指定时相相对应的至少两帧心脏组织图像上设置取样门。
在一些实施例中，超声成像系统还可在基于超声组织图像获得的组织信息的基础上，进一步利用血流和组织的运动信息来确定设置取样门的目标位置。具体地，可向目标区域发射第三超声波，根据第三超声波的回波获得第三超声回波信号，并对第三超声回波信号进行处理，得到目标区域的多普勒数据（包括血流多普勒数据和组织多普勒数据）。随后，根据目标区域的多普勒数据和超声组织图像，确定设置取样门的目标位置。例如，可以基于目标区域的多普勒数据和超声组织图像数据进行融合分析，直接得到设置取样门的目标位置。例如，可以先根据目标区域的多普勒数据确定待设置取样门的位置，再将根据多普勒数据确定的位置映射到超声组织图像上，进而实现超声组织图像上目标位置的自动识别操作。在一些实施方式中，可以基于目标区域的多普勒数据得到目标区域的至少一帧彩色速度图像（包括根据血流多普勒数据得到的彩色血流图像、和根据组织多普勒数据得到的彩色组织图像）。响应于频谱信息获取指令，超声成像系统可以基于至少一帧彩色速度图像识别至少两个用于设置取样门的位置，再根据至少一帧彩色速度图像上用于设置取样门的位置，确定超声组织图像上设置取样门的目标位置。
在一些实施例中，所设置的至少两个取样门中，至少一个取样门的类型区别于其余取样门的类型；设置至少两个取样门时，在至少两个目标位置的第一目标位置设置第一类型取样门，在至少两个目标位置的第二目标位置设置区别于第一类型取样门的第二类型取样门。这里的不同类型的取样门，在一些示例下可以指用于不同成像模式的取样门，并且可以具有不同的取样门宽度、取样门中心位置等特征信息。具体地，以进行心脏E/E’的测量为例，在二尖瓣口的位置处设置第一类型取样门，具体是设置用于血流多普勒成像的取样门，在一个或两个瓣环处设置第二类型取样门，具体是设置用于组织多普勒成像的取样门。
在步骤S204中，向第一目标位置和第二目标位置发射第二超声波，分别在第一目标位置的取样门处和第二目标位置的取样门处进行多普勒成像，并分别获得第一目标位置的取样门处的第一频谱数据、和第二目标位置的取样门处的第二频谱数据。其中若目标位置对应的对象为血流，则进行血流多普勒成像；若目标位置对应的对象为组织，则进行组织多普勒成像。
在本发明的一些实施例中，超声成像系统100可以同步获得各个取样门处的多组频谱数据。对应地，可在第一目标位置和第二目标位置均已设置有取样门后，向第一目标位置和第二目标位置交替发射第二超声波，并根据交替获得的第二超声回波信号，同步获得第一目标位置的取样门处的第一频谱数据和第二目标位置的取样门处的第二频谱数据。在两个目标位置交替发射第二超声波，可以使得超声成像系统100近似同时在两个取样门处进行超声扫描，从而同步获得两个取样门处的频谱数据。
在本发明的一些实施例中，超声成像系统100可以先后获得各个取样门处的多组频谱数据，即先扫描得到一个取样门处的频谱数据后、再扫描得到另一取样门处的频谱数据。例如，可先向第一目标位置发射第二超声波，根据获得的第二超声回波信号，获得第一目标位置的取样门处的第一频谱数据。在已扫描得到第一频谱数据后，再向第二目标位置发射第二超声波，根据此时获得的第二超声回波信号，获得第二目标位置的取样门处的第二频谱数据。第一目标位置和第二目标位置对应两个目标位置时，两个目标位置所对应的频谱数据依次先后获得。第一目标位置和第二目标位置对应超过两个的目标位置时，各个目标位置的频谱数据可依次先后获得，也可以是其中部分目标位置的频谱数据先同步获得、其余目标位置的频谱数据再同步获得，等。
进一步结合步骤S203和步骤S204，步骤S203和步骤S204并不用以限制超声成像方法200的执行先后顺序，超声成像系统100可以是已在第一目标位置和第二目标位置均设置取样门后，再进行扫描以获得各个取样门处的多组频谱数据；也可以是先在第一目标位置设置取样门，进行相应扫描获得该取样门处的第一频谱数据后，再在第二目标位置设置取样门，从而进行扫描以获得该取样门处的第二频谱数据。以第一目标位置和第二目标位置对应两个目标位置为例，超声成像系统100可以是在设置两个取样门后，再对两个目标位置进行交替超声扫描，以同步获得两个取样门处的频谱数据；超声成像系统100可以是在设置两个取样门后，先对其中一个目标位置进行超声扫描、并获得频谱数据后，再对另一个目标位置进行超声扫描；超声成像系统100也可以是先在其中一个目标位置设置取样门，并进行超声扫描获得相应频谱数据，再在另一个目标位置设置取样门，以获得另一个目标位置的取样门处的频谱数据。
该步骤中，超声成像系统100根据发射的第二超声波获得频谱图像，再对频谱图像进行处理得到频谱数据。具体的多普勒成像以获得频谱图像的技术为本领域所熟知，在本申请中不再详细展开。例如，向第一目标位置和第二目标位置发射第二超声波，以分别获得第一频谱数据和第二频谱数据，包括：向第一目标位置发射第二超声波，扫描目标对象后获得第二超声回波信号，基于该第二超声回波信号获得第一频谱图像，并对第一频谱图像自动进行特征值提取，得到第一频谱数据。同样地，向第二目标位置发射第二超声波，扫描目标对象后获得第二超声回波信号，基于该第二超声回波信号获得第二频谱图像，并对第二频谱图像自动进行特征值提取，得到第二频谱数据。特征值提取可包括对频谱图像进行描迹处理，或直接进行幅值提取，描迹处理可以是对频谱图像的波形进行部分描迹或全部描迹，再基于描迹结果进行幅值提取。如图4所示，图4为根据图3的取样门位置B得到的取样门频谱的示意图，可直接基于该取样门频谱进行幅值提取，也可进一步对图4中的取样门频谱进行描迹处理。全部描迹可以获得更符合实际频谱数据的描迹结果，部分描迹则可提高系统自动获得频谱数据的速度。
在一些实施例中，超声成像系统100可接收用户对特征值提取操作的调整，根据调整的特征值提取操作得到第一频谱数据和第二频谱数据。系统进行描迹操作后，用户例如可以调整描迹线的位置，从而调整后续依据描迹结果得到的特征值（如幅值）。
在步骤S205中，根据第一频谱数据和第二频谱数据，获得目标区域的综合频谱信息。在一些实施例中，可以对第一频谱数据和第二频谱数据进行交互分析，从而得到目标区域的综合频谱信息。这里的交互分析指对第一频谱数据和第二频谱数据进行综合分析，例如可以是基于各组频谱数据之间的关系进行综合分析。所获的的综合频谱信息可进一步得以显示输出，例如可以直接显示在超声图像上，可以区别于超声图像单独显示等。
如图5a和图5b所示，以进行心脏E/E’的测量为例，第一目标位置为心脏的二尖瓣口，第一频谱数据为二尖瓣口的取样门处得到的血流多普勒数据。图5a示出了对二尖瓣口处扫描得到的频谱图像，基于该频谱图像得到的血流多普勒数据包括正向第一峰值E和正向第二峰值A。第二目标位置为心脏的瓣环，第二频谱数据为瓣环的取样门处得到的组织多普勒数据（在两个瓣环处设置取样门时，可以取两个瓣环处组织多普勒数据的统计值，作为第二频谱数据）。图5b示出了对瓣环处扫描得到的频谱图像，基于该频谱图像得到的组织多普勒数据包括负向第一峰值E’和负向第二峰值A’。此时，超声成像系统100可计算正向第一峰值E与负向第一峰值E’的比值，和/或计算正向第一峰值E与正向第二峰值A的比值。在该示例下，超声成像系统100进行的交互分析为比值计算。当然，超声成像系统100也可执行除比值计算以外的差值计算、加权相加、加权相乘等处理，以综合考虑第一频谱数据和第二频谱数据，得到包括各个目标位置的目标区域的综合频谱信息。
在其他一些实施例中，超声成像方法还可包括如下步骤：对设置有取样门的超声组织图像进行图像质量评估，并根据图像质量评估结果得到步骤S204中得到的频谱数据（第一频谱数据和第二频谱数据）的置信度。超声成像系统100可以分析超声组织图像的图像清晰度、图像均匀性等属性，从而对超声组织图像进行质量评估。图像质量越高，通常目标位置确定得更为准确，取样门的设置也就更为准确，频谱数据的置信度因而也越高。
在其他一些实施例中，超声成像方法还可包括如下步骤：对第一频谱数据和第二频谱数据进行信噪比评估，并根据信噪比评估结果得到第一频谱数据的置信度和第二频谱数据的置信度。信噪比越高，通常对应频谱数据的置信度也越高。
在一些实施例中，超声成像系统100内部可设置有针对频谱数据置信度的阈值。在确定了各组频谱数据的置信度后，可进一步判断频谱数据的置信度是否符合阈值所定义的有效数据范围。若频谱数据的置信度不符合阈值所定义的有效数据范围，可以提示用户哪一频谱数据置信度低。例如，可以是直接报错并且不输出对应频谱数据和/或综合频谱信息；可以是在输出频谱数据和/或综合频谱信息的同时，通过颜色、图案、声音和/或其组合来提示用户频谱数据的置信度低；可以是在输出频谱数据和/或综合频谱信息的同时，一并输出频谱数据的置信度的值和置信度的参考范围等。
上述结合步骤S201至步骤S205描述的超声成像方法，在以下的至少一项操作中可以是由超声成像系统100自动执行：在至少一帧超声组织图像的第一目标位置处设置第一取样门；在至少一帧超声组织图像的第二目标位置处设置第二取样门；根据第一目标位置处的第二超声回波信号获得第一取样门处的第一频谱数据；根据第二目标位置处的第二超声回波信号获得第二取样门处的第二频谱数据；以及，基于第一频谱数据和第二频谱数据进行交互计算，得到综合频谱信息。该超声成像方法所实现的多个目标位置的取样门设置操作以及后续的频谱分析的自动化，相较于需要医生手动设置取样门、手动进行频谱分析的操作过程，效率更高、整体更智能。
将图2所示的超声成像方法200应用于心脏的E/E’测量时，超声成像系统100可在心脏区域的至少一帧超声组织图像上，将二尖瓣口识别为第一目标位置，在二尖瓣口处设置取样门（例如描述为第一取样门），将一个或多个瓣环识别为第二目标位置，在一个或多个瓣环处设置取样门（例如描述为第二取样门）。该确定目标位置和设置取样门的操作可以是至少部分地由系统自动执行。超声成像系统100在第一取样门处进行血流多普勒成像，向二尖瓣口发射第二超声波，基于二尖瓣口处得到的第二超声回波信号得到血流多普勒图像，对血流多普勒图像进行特征值提取，得到血流多普勒数据，例如为频谱图像上的正向第一峰值。超声成像系统100在第二取样门处进行组织多普勒成像，向一个或多个瓣环发射第二超声波，基于瓣环处得到的第二超声回波信号得到组织多普勒图像，对组织多普勒图像进行特征值提取，得到组织多普勒数据，例如为频谱图像上的负向峰值（可以是多个负向峰值，前文描述的负向第一峰值和负向第二峰值）。该获取频谱数据的操作，同样可以是至少部分地由系统自动执行。超声成像系统100可以计算正向第一峰值与负向第一峰值的比值，和/或计算正向第一峰值与负向第二峰值的比值，将比值作为心脏区域的综合频谱信息。各个步骤的具体过程和可变形方式与上文描述的超声成像方法200相同，在此不再重复描述。
将图2所示的超声成像方法应用于脐带血的S/D测量时，超声成像系统100可在子宫区域的其中一帧包含有脐带口的超声组织图像上，将脐带口识别为第一目标位置，在脐带口处设置取样门（例如描述为第一取样门）；超声成像系统100再在子宫区域的另一帧包含有脐带口的超声组织图像上，在脐带口处再设置一个取样门（例如描述为第二取样门）。该确定目标位置和设置取样门的操作可以是至少部分地由系统自动执行。超声成像系统100分别在第一取样门和第二取样门处进行血流多普勒成像，向脐带口发射第二超声波，基于脐带口处得到的第二超声回波信号得到血流多普勒图像，对血流多普勒图像进行特征值提取，得到两组血流多普勒数据。该获取频谱数据的操作，同样可以是至少部分地由系统自动执行。超声成像系统100可以计算正向第一峰值与负向第一峰值的比值，将比值作为子宫区域的脐带血流的综合频谱信息。各个步骤的具体过程和可变形方式与上文描述的超声成像方法200相同，在此不再重复描述。
结合上述描述可知，本申请中超声成像系统100所能执行的成像方法主要包括如下步骤：在至少一帧超声组织图像的第一目标位置处设置第一取样门；在至少一帧超声组织图像的第二目标位置处设置第二取样门；根据第一目标位置处的第二超声回波信号获得第一取样门处的第一频谱数据；根据第二目标位置处的第二超声回波信号获得第二取样门处的第二频谱数据；以及基于第一频谱数据和第二频谱数据进行交互计算，以得到综合频谱信息。其中，超声成像系统100可以自动执行上述步骤中的至少一项。例如，超声成像系统可以仅自动设置第一取样门，可以仅自动获取第一频谱数据和第二频谱数据，可以自动设置第一取样门并自动获得第一频谱数据等。以进行心脏E/E’测量为例，可以仅在瓣环处自动设置取样门和自动获得相应频谱数据，而保留用户手动设置二尖瓣口处的取样门和手动获取二尖瓣口处频谱数据的操作；可以仅自动获得二尖瓣口和瓣环处的频谱数据，但保留用户手动设置取样门的操作；也可以全自动设置二尖瓣口和瓣环处的取样门以及获得相应频谱数据。例如，超声成像系统可以仅自动获得综合频谱信息，可以自动获得第一频谱数据和第二频谱数据，并基于第一频谱数据和第二频谱数据自动得到综合频谱信息。同样以进行心脏E/E’测量为例，可以仅在得到瓣环和二尖瓣口处的频谱数据后，自动计算获得二尖瓣口和瓣环的综合频谱信息；也可以是分别自动获得二尖瓣口处频谱数据和瓣环处频谱数据，并基于这两个目标部位的频谱数据自动计算获得综合频谱信息。通过超声成像系统100自动执行此处所描述的至少一项步骤，可以提高用户利用超声成像系统进行多个目标部位的综合评估的操作效率。
在另一实施例中，本申请还可提供图2的超声成像方法的变形，将超声成像方法的成像对象设定为多个（至少两个）目标区域。该超声成像方法600如图6所示，可具体可包括如下步骤S601至步骤S605。
在步骤S601中，向多个目标区域分别发射第一超声波，并接收自多个目标区域分别返回的超声回波，获得多个第一超声回波信号。同样，多个目标区域可以选自人体心脏、胎儿心脏、胎儿脐动脉或其他器官组织；向多个目标区域发射的第一超声波同样是以获得超声组织图像为目的。
在步骤S602中，对多个第一超声回波信号进行处理得到各个目标区域的超声组织图像。可对步骤S601中获的的第一超声回波信号进行波束合成、包络求解等处理，进而得到超声组织图像。
在步骤S603中，在各个目标区域的超声组织图像上分别设置取样门。该步骤中同样先确定各个超声组织图像上的目标位置，再在各个目标位置处设置取样门。每个目标区域的用以设置取样门的超声组织图像可以是一帧，也可以是多帧。在一帧超声组织图像上，可以设置一个取样门，也可以设置多个取样门。当每个目标区域对应的取样门不唯一时，后续步骤中对获得的频谱数据可进行统计处理，例如求取频谱数据的均值、中位值等。
该步骤中超声成像系统100可自动设置取样门。系统可自动识别出一帧超声组织图像上的目标部位，作为待设置取样门的目标位置，在各个目标位置对应的目标部位处分别设置取样门。一种方式下，可基于机器学习或深度学习的方法识别各个目标部位。一种方式下，可根据各目标部位的图像特征或运动特征进行自动识别。目标部位的位置确定后，则可在目标位置处设置取样门；取样门的设置过程为常规技术，在此不再展开描述。与方法200相同，用户可以调整已自动设置的取样门的设置位置，可以输入待识别目标位置的图像范围等。
在步骤S604中，向各个取样门的目标位置分别发射第二超声波，以获得各个取样门处的多个频谱图像。该获得频谱图像的过程可以参考本领域所熟知的多普勒成像过程，在此不详细展开。
在该步骤中，进一步根据多个频谱图像获得多组频谱数据。具体地，可对各个频谱图像进行特征值提取，从而得到各个频谱图像对应的一个或多个特征值，作为各个频谱图像对应的一组频谱数据。如上所述，可通过描迹处理或幅值提取进行特征值提取。应该理解的是，上述步骤S603至S604并未限定超声成像方法的执行先后顺序。在一个实施例中，可以是先设置多个取样门后，再向各个取样门处交替发射第二超声波，以同步获得多个频谱图像和近一步的多组频谱数据。在一个实施例中，可以是在设置了多个取样门后，先向其中一个取样门处发射第二超声波，获得频谱图像并计算获得相应频谱数据，再向另一取样门处发射第二超声波，以获得另一取样门处的频谱图像和相应频谱数据，如此类推。在一个实施例中，可以是先在一个目标位置设置取样门、对该位置的取样门发射超声波、获得频谱图像和相应频谱数据，再在另一个目标位置设置取样门、对该另一取样门发射超声波、获得频谱图像和相应频谱数据。
在步骤S605中，对多组频谱数据进行交互分析，得到综合频谱信息。这里的交互分析指对第一频谱数据和第二频谱数据进行综合分析，例如可以是基于各组频谱数据之间的关系进行综合分析。结合步骤S604，可以分别取多组频谱数据的一个或多个特征值，在多组频谱数据的特征值之间进行交互计算，计算结果即为综合频谱信息。可以先从多组频谱数据中选出至少两组频谱数据，再取选定组的频谱数据的一个或多个特征值，基于选定组的特征值进行交互计算。所获的的综合频谱信息可进一步得以显示输出，例如可以直接显示在超声图像上，也可以区别于超声图像单独显示等。
进一步结合图1，本发明的超声成像系统100可执行上述超声成像方法200和600，从而获得至少两个目标位置的频谱数据，并基于多个频谱数据获得综合频谱信息。包括超声探头110、发射电路112、接收电路114、波束合成电路116、处理器118、显示器120、发射/接收选择开关122以及存储器124。
在一个实施例中，超声成像系统100的超声探头110可用于向目标区域发射第一超声波和基于第一超声波的回波获得第一超声回波信号，以使超声成像系统后续能够得到超声组织图像。例如，超声探头110可在取样门设置前，向心脏区域发射第一超声波，接收自心脏区域返回的第一超声波的回波，并基于第一超声波的回波获得第一超声回波信号。
在一个实施例中，超声成像系统100的超声探头110可用于向目标区域发射第二超声波和基于第二超声波的回波获得第二超声回波信号，以使超声成像系统后续能够得到频谱数据。例如，超声探头100可在取样门设置后，分别向设置有取样门的第一目标位置和第二目标位置发射第二超声波，接收取样门设置位置处返回的回波，并基于该回波获得多个第二超声回波信号。
在一个实施例中，超声成像系统100的发射/接收控制电路可用于控制超声探头100发射超声探头110发射超声波（第一超声波和第二超声波）和接收超声波的回波以获得第二超声回波信号。
在一个实施例中，超声成像系统100的处理器118可用于对第一超声回波信号进行处理以得到至少一帧超声组织图像，可在至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门，并基于多个取样门处的第二超声回波信号获得多个频谱数据，可对多个频谱数据进行交互分析得到综合频谱信息。例如，处理器118可对心脏区域的第一超声回波信号进行处理，得到心脏区域的至少一帧超声组织图像。处理器118可在心脏区域的至少一帧超声组织图像的二尖瓣口处设置第一取样门以进行血流多普勒成像，在心脏区域的至少一帧超声组织图像的瓣环处设置第二取样门以进行组织多普勒成像，根据二尖瓣口处的第二超声回波信号获得第一取样门处的第一频谱数据，根据瓣环处的第二超声回波信号获得第二取样门处的第二频谱数据。处理器118可对第一频谱数据和第二频谱数据进行交互分析得到综合频谱信息。
在一个实施例中，超声成像系统100的处理器118可自动设置第一取样门和第二取样门的至少一个。例如，处理器118可单独在二尖瓣口处自动设置第一取样门，处理器118可单独在瓣环处自动设置第二取样门，处理器118也可以在二尖瓣口和瓣环处均自动设置取样门。
在一个实施例中，超声成像系统100的处理器118可根据第二超声回波信号获得第一频谱数据和第二频谱数据。例如，处理器118可基于二尖瓣口处得到的第二超声回波信号得到血流多普勒图像，对血流多普勒图像进行特征值提取，得到血流多普勒数据。处理器118基于瓣环处得到的第二超声回波信号得到组织多普勒图像，对组织多普勒图像进行特征值提取，得到组织多普勒数据。
在一个实施例中，超声成像系统100的处理器118可自动对血流多普勒图像和组织多普勒图像的至少一个进行特征值提取。例如，以心脏的E/E’测量为例，处理器118可对瓣环处得到的组织多普勒图像自动进行特征值提取；处理器118可对二尖瓣口处得到的血流多普勒图像自动进行特征值提取；处理器118可对瓣环处的组织多普勒图像和二尖瓣口处得到的血流多普勒图像自动进行特征值提取。对二尖瓣口处的血流多普勒图像进行特征值提取，可得到血流多普勒数据，该血流多普勒数据包括正向第一峰值。对瓣环处的组织多普勒图像进行特征值提取，可到组织多普勒数据，该组织多普勒数据可把扩负向第一峰值和负向第二峰值。后续处理器118可计算正向第一峰值和负向第一峰值的比值，得到综合频谱信息；也可计算正向第一峰值和负向第二峰值的比值，同样得到另一维度的综合频谱信息。
在一个实施例中，超声成像系统100的处理器118可在二尖瓣口和瓣环处已分别设置有取样门后，通过发射/接收控制电路控制超声探头向二尖瓣口和瓣环处交替发射第二超声波，从而同步获得二尖瓣口处的第一频谱数据和瓣环处的第二频谱数据。
在一个实施例中，超声成像系统100的处理器118可通过发射/接收控制电路控制超声探头向二尖瓣口处发射第二超声波，处理器118在获得二尖瓣口处的第一频谱数据后，再通过发射/接收控制电路控制超声探头向瓣环处发射第二超声波，以再获得瓣环处的第二频谱数据。在本发明的各种实施例中，超声成像系统100既可以支持同步获得多个目标位置的频谱数据，也可以先后获得多个目标位置的频谱数据。
在一个实施例中，超声成像系统100可配置有触发频谱信息获取的按键，该按键可以是专门设置的、用于启动频谱信息获取的按键，也可以是一个或多个成像模式切换按键，这些成像模式切换按键在切换成像模式的同时，可供用户进一步选择是否要启动频谱信息的获取。在进行心脏的E/E’测量时，超声成像系统100首先获取到心脏区域的至少一帧超声组织图像，在从组织灰度成像模式切换到血流多普勒成像或组织多普勒成像时，则可以进一步选择触发频谱信息的获取，并可以将与成像模式切换按键被触发的时间对应的一帧超声图像作为待设置取样门的超声组织图像。对于心脏的E/E’测量而言，可以获取心电信号，并将与心电信号的指定时相相对应的一帧或多帧超声组织图像，作为待设置取样门的超声组织图像。超声成像系统100还可以基于方法200中描述的其他方式，确定用于设置取样门的超声组织图像。
此外，根据本申请实施例，还提供了一种存储介质，在所述存储介质上存储了程序指令，在所述程序指令被计算机或处理器（诸如前述的处理器118）运行时用于执行本申请实施例的超声成像方法200和/或600的相应步骤。所述存储介质例如可以包括智能电话的存储卡、平板电脑的存储部件、个人计算机的硬盘、只读存储器(ROM)、可擦除可编程只读存储器(EPROM)、便携式紧致盘只读存储器(CD-ROM)、USB存储器、或者上述存储介质的任意组合。所述计算机可读存储介质可以是一个或多个计算机可读存储介质的任意组合。
此外，根据本申请实施例，还提供了一种计算机程序，该计算机程序可以存储在云端或本地的存储介质上。在该计算机程序被计算机或处理器运行时用于执行本申请实施例的超声图像分析方法的相应步骤。
基于上面的描述，根据本申请实施例的超声成像方法、超声成像系统和计算机存储介质自动进行设置取样门、获取频谱数据和计算综合频谱信息的至少一项，该自动化的操作方式，可以很好地减轻进行综合频谱分析的工作量，使超声诊断更能满足临床需求。
尽管这里已经参考附图描述了示例实施例，应理解上述示例实施例仅仅是示例性的，并且不意图将本申请的范围限制于此。本领域普通技术人员可以在其中进行各种改变和修改，而不偏离本申请的范围和精神。所有这些改变和修改意在被包括在所附权利要求所要求的本申请的范围之内。
本领域普通技术人员可以意识到，结合本文中所公开的实施例描述的各示例的单元及算法步骤，能够以电子硬件、或者计算机软件和电子硬件的结合来实现。这些功能究竟以硬件还是软件方式来执行，取决于技术方案的特定应用和设计约束条件。专业技术人员可以对每个特定的应用来使用不同方法来实现所描述的功能，但是这种实现不应认为超出本申请的范围。
在本申请所提供的几个实施例中，应该理解到，所揭露的设备和方法，可以通过其它的方式实现。例如，以上所描述的设备实施例仅仅是示意性的，例如，所述单元的划分，仅仅为一种逻辑功能划分，实际实现时可以有另外的划分方式，例如多个单元或组件可以结合或者可以集成到另一个设备，或一些特征可以忽略，或不执行。
在此处所提供的说明书中，说明了大量具体细节。然而，能够理解，本申请的实施例可以在没有这些具体细节的情况下实践。在一些实例中，并未详细示出公知的方法、结构和技术，以便不模糊对本说明书的理解。
类似地，应当理解，为了精简本申请并帮助理解各个发明方面中的一个或多个，在对本申请的示例性实施例的描述中，本申请的各个特征有时被一起分组到单个实施例、图、或者对其的描述中。然而，并不应将该本申请的方法解释成反映如下意图：即所要求保护的本申请要求比在每个权利要求中所明确记载的特征更多的特征。更确切地说，如相应的权利要求书所反映的那样，其发明点在于可以用少于某个公开的单个实施例的所有特征的特征来解决相应的技术问题。因此，遵循具体实施方式的权利要求书由此明确地并入该具体实施方式，其中每个权利要求本身都作为本申请的单独实施例。
本领域的技术人员可以理解，除了特征之间相互排斥之外，可以采用任何组合对本说明书（包括伴随的权利要求、摘要和附图）中公开的所有特征以及如此公开的任何方法或者设备的所有过程或单元进行组合。除非另外明确陈述，本说明书（包括伴随的权利要求、摘要和附图）中公开的每个特征可以由提供相同、等同或相似目的的替代特征来代替。
此外，本领域的技术人员能够理解，尽管在此所述的一些实施例包括其它实施例中所包括的某些特征而不是其它特征，但是不同实施例的特征的组合意味着处于本申请的范围之内并且形成不同的实施例。例如，在权利要求书中，所要求保护的实施例的任意之一都可以以任意的组合方式来使用。
本申请的各个部件实施例可以以硬件实现，或者以在一个或者多个处理器上运行的软件模块实现，或者以它们的组合实现。本领域的技术人员应当理解，可以在实践中使用微处理器或者数字信号处理器（DSP）来实现根据本申请实施例的一些模块的一些或者全部功能。本申请还可以实现为用于执行这里所描述的方法的一部分或者全部的装置程序（例如，计算机程序和计算机程序产品）。这样的实现本申请的程序可以存储在计算机可读介质上，或者可以具有一个或者多个信号的形式。这样的信号可以从因特网网站上下载得到，或者在载体信号上提供，或者以任何其他形式提供。
应该注意的是上述实施例对本申请进行说明而不是对本申请进行限制，并且本领域技术人员在不脱离所附权利要求的范围的情况下可设计出替换实施例。在权利要求中，不应将位于括号之间的任何参考符号构造成对权利要求的限制。本申请可以借助于包括有若干不同元件的硬件以及借助于适当编程的计算机来实现。在列举了若干装置的单元权利要求中，这些装置中的若干个可以是通过同一个硬件项来具体体现。单词第一、第二、以及第三等的使用不表示任何顺序。可将这些单词解释为名称。
以上所述，仅为本申请的具体实施方式或对具体实施方式的说明，本申请的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本申请揭露的技术范围内，可轻易想到变化或替换，都应涵盖在本申请的保护范围之内。本申请的保护范围应以权利要求的保护范围为准。

Claims (43)

  1. 一种超声成像方法，其特征在于，包括：
    向目标区域发射第一超声波，并接收自所述目标区域返回的超声回波，获得第一超声回波信号；
    对所述第一超声回波信号进行处理得到所述目标区域的至少一帧超声组织图像；
    响应于频谱信息获取指令，在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门；
    向所述第一目标位置和第二目标位置发射第二超声波，以分别获得所述第一目标位置的取样门处的第一频谱数据和所述第二目标位置的取样门处的第二频谱数据；以及
    根据所述第一频谱数据和第二频谱数据获得所述目标区域的综合频谱信息。
  2. 根据权利要求1所述的方法，其特征在于，所述向所述第一目标位置和第二目标位置发射第二超声波，以分别获得所述第一目标位置的取样门处的第一频谱数据和所述第二目标位置的取样门处的第二频谱数据，包括：
    向所述第一目标位置和第二目标位置交替发射所述第二超声波，以同步获得所述第一频谱数据和第二频谱数据。
  3. 根据权利要求1所述的方法，其特征在于，所述向所述第一目标位置和第二目标位置发射第二超声波，以分别获得所述第一目标位置的取样门处的第一频谱数据和所述第二目标位置的取样门处的第二频谱数据，包括：
    先向所述第一目标位置发射所述第二超声波，并获得所述第一目标位置的取样门处的第一频谱数据；
    再向所述第二目标位置发射所述第二超声波，并获得所述第二目标位置的取样门处的第二频谱数据。
  4. 根据权利要求1至3任一项所述的方法，其特征在于，所述至少一帧超声组织图像包括多帧超声组织图像时，在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门包括：在与所述频谱信息获取指令的触发时间对应的一帧超声组织图像上设置所述取样门。
  5. 根据权利要求1至3任一项所述的方法，其特征在于，所述至少一帧超声组织图像包括多帧超声组织图像时，在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门包括：
    从所述多帧超声组织图像选择至少两帧超声组织图像，在选择的至少两帧超声组织图像上设置所述取样门，并根据所选择的各帧超声组织图像上取样门的位置计算设置所述取样门的所述第一目标位置和第二目标位置。
  6. 根据权利要求1至3任一项所述的方法，其特征在于，所述至少一帧超声组织图像包括多帧心脏组织图像时，在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门包括：
    获取心电信号；
    在与所述心电信号的指定时相对应的一帧超声组织图像上设置所述取样门。
  7. 根据权利要求1至3任一项所述的方法，其特征在于，还包括：
    向所述目标区域发射第三超声波，根据所述第三超声波的回波获得第三超声回波信号，并对所述第三超声回波信号进行处理得到所述目标区域的多普勒数据；
    响应于所述频谱信息获取指令，根据所述目标区域的多普勒数据、以及所述目标区域的至少一帧超声组织图像，确定所述超声组织图像上设置所述取样门的所述第一目标位置和第二目标位置。
  8. 根据权利要求1至3任一项所述的方法，其特征在于，所述至少一帧超声组织图像包括多帧超声组织图像时，所述在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门，包括：
    在所述多帧超声组织图像的至少两帧超声组织图像上分别确定所述第一目标位置和第二目标位置，在各目标位置处分别设置取样门；
    或者，在所述多帧超声组织图像的其中一帧超声组织图像上确定所述第一目标位置和第二目标位置，在各目标位置处分别设置取样门。
  9. 根据权利要求1至8任一项所述的方法，其特征在于，还包括：
    对设置有所述取样门的超声组织图像进行图像质量评估；
    根据所述图像质量评估结果得到所述第一频谱数据的置信度和第二频谱数据的置信度。
  10. 根据权利要求1至8任一项所述的方法，其特征在于，还包括：对所述第一频谱数据和第二频谱数据进行信噪比评估，根据所述信噪比评估结果得到所述第一频谱数据的置信度和所述第二频谱数据的置信度。
  11. 根据权利要求1至10任一项所述的方法，其特征在于，所述根据所述第一频谱数据和第二频谱数据获得所述目标区域的综合频谱信息包括：对所述第一频谱数据和第二频谱数据进行交互分析得到综合频谱信息，并显示输出所述综合频谱信息。
  12. 根据权利要求1至11任一项所述的方法，其特征在于，所述在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门，包括：
    在所述第一目标位置设置第一类型取样门；
    在所述第二目标位置设置区别于第一类型取样门的第二类型取样门。
  13. 根据权利要求1至12任一项所述的方法，其特征在于，所述向所述第一目标位置和第二目标位置发射第二超声波，以分别获得所述第一目标位置的取样门处的第一频谱数据和所述第二目标位置的取样门处的第二频谱数据，包括：
    根据向所述第一目标位置发射的所述第二超声波获得第一频谱图像，并对所述第一频谱图像自动进行特征值提取，得到所述第一频谱数据；
    根据向所述第二目标位置发射的所述第二超声波获得第二频谱图像，并对所述第二频谱图像自动进行特征值提取，得到所述第二频谱数据。
  14. 根据权利要求13所述的方法，其特征在于，还包括：接收用户对特征值提取操作的调整，根据调整的特征值提取操作得到所述第一频谱数据和所述第二频谱数据。
  15. 根据权利要求1至14任一项所述的方法，其特征在于，还包括：接收用户对已设置的取样门的位置的调整，在调整后的位置处分别设置取样门。
  16. 根据权利要求1至15任一项所述的方法，其特征在于，所述在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门，包括：
    自动识别所述至少一帧超声组织图像的第一目标部位和第二目标部位，在各目标部位分别设置所述取样门。
  17. 根据权利要求16所述的方法，其特征在于，所述自动识别所述至少一帧超声组织图像的第一目标部位和第二目标部位包括：
    基于机器学习或深度学习的方法识别所述第一目标部位和第二目标部位；
    或者，根据所述第一目标部位的图像特征或运动特征、和根据第二目标部位的图像特征或运动特征进行自动识别。
  18. 一种超声成像系统，其特征在于，包括：
    超声探头，用于在取样门设置前向心脏区域发射第一超声波、接收所述第一超声波的回波、并基于所述第一超声波的回波获取第一超声回波信号，在所述取样门设置后向均设置有所述取样门的第一目标位置和第二目标位置发射第二超声波、接收所述第二超声波的回波、并基于所述第二超声波的回波获取第二超声回波信号；
    发射/接收控制电路，用于在取样门设置前控制所述超声探头发射第一超声波、并基于所述第一超声波的回波获取第一超声回波信号，在所述取样门设置后控制所述超声探头发射第二超声波、并基于所述第二超声波的回波获取第二超声回波信号；
    处理器，用于：
    对所述第一超声回波信号进行处理得到所述心脏区域的至少一帧超声组织图像；
    在所述至少一帧超声组织图像的所述第一目标位置设置取样门，并根据所述第二超声回波信号获得所述第一目标位置的取样门处的第一频谱数据；
    在所述至少一帧超声组织图像的所述第二目标位置设置取样门，并根据所述第二超声回波信号获得所述第二目标位置的取样门处的第二频谱数据；以及
    对所述第一频谱数据和第二频谱数据进行交互分析得到综合频谱信息；
    显示器，用于显示所述综合频谱信息。
  19. 根据权利要求18所述的系统，其特征在于，所述处理器在所述至少一帧超声组织图像的所述第一目标位置设置取样门包括：在所述至少一帧超声组织图像的二尖瓣口处设置第一取样门，以进行血流多普勒成像；
    所述处理器在所述至少一帧超声组织图像的所述第二目标位置设置取样门包括：在所述至少一帧超声组织图像的瓣环处设置第二取样门，以进行组织多普勒成像。
  20. 根据权利要求19所述的系统，其特征在于，所述处理器在所述二尖瓣口处自动设置所述第一取样门，和/或所述处理器在所述瓣环处自动设置所述第二取样门。
  21. 根据权利要求20所述的系统，其特征在于，所述系统还包括取样门设置按键；所述处理器还用于接收用户通过所述取样门设置按键对已设置的取样门的位置的调整，在调整后的位置处分别设置所述取样门。
  22. 根据权利要求19所述的系统，其特征在于，所述处理器根据所述第二超声回波信号获得所述第一频谱数据包括：基于所述二尖瓣口处得到的第二超声回波信号得到血流多普勒图像，对所述血流多普勒图像进行特征值提取，得到血流多普勒数据；以及
    所述处理器根据所述第二超声回波信号获得所述第二频谱数据包括：基于所述瓣环处得到的第二超声回波信号得到组织多普勒图像，对所述组织多普勒图像进行特征值提取，得到组织多普勒数据。
  23. 根据权利要求22所述的系统，其特征在于，所述处理器自动对所述血流多普勒图像进行特征值提取，和/或所述处理器自动对所述组织多普勒图像进行特征值提取。
  24. 根据权利要求23所述的系统，其特征在于，所述系统还包括特征值提取按键；所述处理器还用于接收用户通过所述特征值提取按键对特征值提取操作的调整，根据调整的特征值提取操作得到所述血流多普勒数据和/或所述组织多普勒数据。
  25. 根据权利要求21所述的系统，其特征在于，所述血流多普勒数据包括正向第一峰值，所述组织多普勒数据包括负向第一峰值和负向第二峰值；
    所述对所述第一频谱数据和第二频谱数据进行交互分析得到综合频谱信息包括：计算所述正向第一峰值与负向第一峰值的比值，和/或计算所述正向第一峰值与负向第二峰值的比值。
  26. 根据权利要求18至25任一项所述的系统，其特征在于，所述发射/接收控制电路控制所述超声探头向所述第一目标位置和所述第二目标位置交替发射所述第二超声波，以同步获得所述二尖瓣口处的第一频谱数据和所述瓣环处的第二频谱数据。
  27. 根据权利要求18至25任一项所述的系统，其特征在于，所述发射/接收控制电路控制所述超声探头先向所述第一目标位置发射所述第二超声波，在获得该第一目标位置的第一频谱数据后，再向所述第二目标位置发射所述第二超声波，以获得该第二目标位置的第二频谱数据。
  28. 根据权利要求18至25任一项所述的系统，其特征在于，所述至少一帧超声组织图像包括多帧超声组织图像，所述系统还包括成像模式切换按键；
    所述处理器在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门包括：在与所述成像模式切换按键被触发的时间对应的一帧超声组织图像上设置所述取样门。
  29. 根据权利要求18至25任一项所述的系统，其特征在于，所述至少一帧超声组织图像包括多帧超声组织图像，所述处理器在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门包括：
    从所述多帧超声组织图像选择至少两帧超声组织图像，在选择的至少两帧超声组织图像上设置所述取样门，并根据所选择的各帧超声组织图像上取样门的位置计算设置所述取样门的第一目标位置和第二目标位置。
  30. 根据权利要求18至25任一项所述的系统，其特征在于，所述至少一帧超声组织图像包括多帧超声组织图像，所述处理器在所述至少一帧超声组织图像的第一目标位置和第二目标位置分别设置取样门包括：
    获取心电信号；
    在与所述心电信号的指定时相对应的一帧超声组织图像上设置所述取样门。
  31. 一种超声成像方法，其特征在于，包括：
    向多个目标区域发射第一超声波，并接收自所述多个目标区域分别返回的超声回波，获得多个第一超声回波信号；
    对所述多个第一超声回波信号进行处理得到各个目标区域的超声组织图像；
    在所述各个目标区域的超声组织图像上分别设置取样门；以及
    向所述各个取样门的目标位置分别发射第二超声波，以获得各个取样门处的多个频谱图像；
    根据所述多个频谱图像获得多组频谱数据；以及
    对所述多组频谱数据进行交互分析，得到综合频谱信息。
  32. 根据权利要求31所述的方法，其特征在于，所述根据所述多个频谱图像获得多组频谱数据包括：对各所述频谱图像进行特征值提取，以得到各所述频谱图像的一个或多个特征值，作为所述一组频谱数据。
  33. 根据权利要求32所述的方法，其特征在于，所述对各所述频谱图像进行特征值提取包括对各所述频谱图像进行描迹处理或幅值提取。
  34. 根据权利要求32或33所述的方法，其特征在于，所述对所述多组频谱数据进行交互分析，得到综合频谱信息，包括：
    选定至少两组频谱数据，取各选定组的频谱数据的一个或多个特征值，在各选定组的频谱数据的特征值之间进行交互计算，将计算结果作为所述综合频谱信息。
  35. 根据权利要求31所述的方法，其特征在于，所述各个取样门包括血流多普勒取样门和组织多普勒取样门。
  36. 根据权利要求31所述的方法，其特征在于，所述在所述各个目标区域的超声组织图像上分别设置取样门包括：识别所述超声组织图像上的一个或多个目标部位，在所述一个或多个目标部位的位置自动设置取样门。
  37. 一种超声成像系统，其特征在于，包括：
    超声探头，用于在取样门设置前向目标区域发射第一超声波、接收所述第一超声波的回波、并基于所述第一超声波的回波获取第一超声回波信号，在所述取样门设置后向设置有所述取样门的至少两个目标位置发射第二超声波、接收所述第二超声波的回波、并基于所述第二超声波的回波获取第二超声回波信号；
    发射/接收控制电路，用于在取样门设置前控制所述超声探头发射第一超声波、并基于所述第一超声波的回波获取第一超声回波信号，在所述取样门设置后控制所述超声探头发射第二超声波、并基于所述第二超声波的回波获取第二超声回波信号；
    处理器，用于对所述第一超声回波信号进行处理得到所述目标区域的至少一帧超声组织图像；所述处理器还用于自动执行以下的至少一项：
    在所述至少一帧超声组织图像的第一目标位置处设置第一取样门；
    在所述至少一帧超声组织图像的第二目标位置处设置第二取样门；
    根据所述第一目标位置处的所述第二超声回波信号获得所述第一取样门处的第一频谱数据；以及
    根据所述第二目标位置处的所述第二超声回波信号获得所述第二取样门处的第二频谱数据；
    显示器，用于显示设置有第一取样门和/或第二取样门的超声组织图像。
  38. 根据权利要求37所述的系统，其特征在于，所述系统包括血流多普勒成像按键和组织多普勒成像按键；所述处理器用于：
    响应于所述血流多普勒成像按键的触发，在所述至少一帧超声组织图像上设置所述第一取样门；响应于所述组织多普勒成像按键的触发，在所述至少一帧超声组织图像上设置所述第二取样门。
  39. 根据权利要求37所述的系统，其特征在于，所述系统包括频谱信息获取按键；所述处理器用于：
    响应于所述频谱信息获取按键的触发，在所述至少一帧超声组织图像上设置所述第一取样门和所述第二取样门。
  40. 根据权利要求39所述的系统，其特征在于，所述至少一帧超声组织图像包括至少一帧心脏组织图像；响应于所述频谱信息获取按键的触发，在所述至少一帧心脏组织图像的二尖瓣口处设置所述第一取样门，在所述至少一帧心脏组织图像的一个或多个瓣环处设置所述第二取样门。
  41. 根据权利要求39所述的系统，其特征在于，所述至少一帧超声组织图像包括多帧胎儿脐带图像；响应于所述频谱信息获取按键的触发，在所述多帧胎儿脐带图像的其中一帧图像的脐带口处设置所述第一取样门，在多帧胎儿脐带图像的另一帧图像的脐带口处设置所述第二取样门。
  42. 根据权利要求37至41中任一项所述的系统，其特征在于，所述处理器还用于基于所述第一频谱数据和所述第二频谱数据的交互计算，得到综合频谱信息，并控制所述显示器显示所述综合频谱信息。
  43. 一种计算机存储介质，其上存储有计算机程序，其特征在于，所述计算机程序被计算机或处理器执行时实现权利要求1至18中任一项所述方法的步骤。
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