WO2022075656A1 - Procédé de fabrication d'une structure de cavité abdominale à l'aide d'une impression 3d et structure de cavité abdominale utilisant un tel procédé - Google Patents

Procédé de fabrication d'une structure de cavité abdominale à l'aide d'une impression 3d et structure de cavité abdominale utilisant un tel procédé Download PDF

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WO2022075656A1
WO2022075656A1 PCT/KR2021/013356 KR2021013356W WO2022075656A1 WO 2022075656 A1 WO2022075656 A1 WO 2022075656A1 KR 2021013356 W KR2021013356 W KR 2021013356W WO 2022075656 A1 WO2022075656 A1 WO 2022075656A1
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abdominal cavity
structures
cavity structure
manufacturing
image
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PCT/KR2021/013356
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English (en)
Korean (ko)
Inventor
유진수
조재원
최규성
김종만
김미승
Original Assignee
사회복지법인 삼성생명공익재단
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Publication of WO2022075656A1 publication Critical patent/WO2022075656A1/fr

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30Auxiliary operations or equipment
    • B29C64/386Data acquisition or data processing for additive manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computerised tomographs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00Data acquisition or data processing for additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T17/00Three dimensional [3D] modelling, e.g. data description of 3D objects
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/753Medical equipment; Accessories therefor
    • B29L2031/7532Artificial members, protheses

Definitions

  • the present invention relates to a method for manufacturing a abdominal cavity structure and a abdominal cavity structure using the same, and more particularly, to a method for manufacturing a abdominal cavity structure using 3D printing and a abdominal cavity structure manufactured accordingly.
  • a transplant recipient who will receive a liver from a donor When selecting a transplant recipient who will receive a liver from a donor, such as a brain dead, a decision is made by considering not only how urgently a liver transplant is needed, but also blood type and body size. At this time, there are cases in which surgery is performed without accurately determining the size or shape of the donor's liver. Alternatively, there is a case where the transplantation operation of a donor is performed in another hospital without a transplant recipient, and thus whether the liver is suitable for transplantation depends entirely on the judgment of the transplant surgeon. Due to this, there is a risk that the liver graft removed from the donor is too large or too small for the size of the recipient's abdominal cavity, and thus the transplantation fails.
  • the present invention is to solve the above-mentioned problems, and provides a method for manufacturing an abdominal cavity structure using 3D printing and a method for manufacturing an abdominal cavity using the 3D printing, which implements the shape or size of the abdominal cavity of a transplant recipient as it is, so that a liver transplantation operation can be performed safely and efficiently can do.
  • a method for manufacturing a abdominal cavity structure is a method for manufacturing a abdominal cavity structure using 3D printing, comprising the steps of obtaining an abdominal cavity structure image through computerized imaging, dividing the obtained image into a plurality of regions, the Acquiring a plurality of reference lines in a plurality of divided regions, and modeling a plurality of first structures based on the obtained plurality of reference lines.
  • the step of dividing the image into a plurality of regions divides the image so that at least one of the diaphragm, rib cage, inferior vena cava and kidney is identified in the plurality of regions. can do.
  • the plurality of reference lines are spaced apart in one direction based on the divided plurality of regions, and on the inner wall of the abdominal cavity It may be a plurality of corresponding profiles.
  • the obtaining of the plurality of reference lines may vary the number of the reference lines according to the thickness of the abdominal cavity identified in the acquired image.
  • the plurality of baselines overlap with at least one of the diaphragm, rib cage, inferior vena cava and kidney.
  • the modeling of the plurality of first structures may be manufactured by stacking the plurality of obtained reference lines to have a predetermined width and width.
  • the method may further include modeling a plurality of second structures supporting each of the modeled plurality of first structures.
  • the modeling of the plurality of second structures includes setting at least one or more support points for each of the plurality of first structures, and the second structure is the support point. It can be provided with a support groove corresponding to the curvature of the first structure in the.
  • the modeling of the plurality of second structures includes the plurality of second structures having a predetermined support surface, and at a position connected to the first structure. Depending on the length, it can be laminated to have different lengths.
  • the method may further include modeling a plurality of third structures supporting each of the modeled plurality of second structures.
  • the plurality of third structures may include an insertion groove into which one end of the plurality of second structures is inserted.
  • Abdominal cavity structure based on the abdominal cavity image obtained through computer imaging, corresponding to the inner wall profile of the abdominal cavity, a plurality of first structures disposed spaced apart by a predetermined interval in one direction, the It includes a plurality of second structures supporting each of the plurality of first structures, and a plurality of third structures supporting lower ends of the plurality of second structures and disposed on a fourth structure having a flat plate shape.
  • the plurality of first structures may be arranged to overlap at least one of the diaphragm, the rib cage, the inferior vena cava and the kidney in a cross-section based on the acquired abdominal cavity image.
  • one end of the plurality of second structures is connected to the first structure, the other end is connected to the third structure, and one end is connected to the curvature of the first structure.
  • a corresponding support groove may be provided.
  • the plurality of second structures may have a flat support surface at the other end, and may have different lengths depending on positions connected to the first structures.
  • the plurality of third structures may have an insertion groove into which one end of the plurality of second structures is inserted.
  • an abdominal cavity structure simulating the abdominal cavity structure of a subject including major body structures located around the subject's liver, can be used for liver transplantation .
  • an abdominal cavity structure simulating the abdominal cavity structure of a subject including major body structures located around the subject's liver, can be used for liver transplantation .
  • the abdominal cavity structure manufacturing method and the abdominal cavity structure using the same use 3D printing technology to simulate the abdominal cavity structure of a subject in consideration of the minimum major body structures to be considered during liver transplantation, thereby expediting liver transplantation surgery and can proceed accurately.
  • FIG. 1 shows a method for manufacturing a abdominal cavity structure according to an embodiment of the present invention.
  • FIGS. 2 and 3 schematically show a state in which an abdominal cavity image is acquired according to an embodiment of the present invention.
  • FIG 5 and 6 show a abdominal cavity structure according to an embodiment of the present invention.
  • FIG. 7 shows a third structure according to an embodiment of the present invention.
  • FIG. 8 shows a liver transplantation operation using an abdominal cavity structure according to an embodiment of the present invention.
  • a method for manufacturing a abdominal cavity structure is a method for manufacturing a abdominal cavity structure using 3D printing, comprising the steps of obtaining an abdominal cavity structure image through computerized imaging, dividing the obtained image into a plurality of regions, the Acquiring a plurality of reference lines in a plurality of divided regions, and modeling a plurality of first structures based on the obtained plurality of reference lines.
  • the x-axis, the y-axis, and the z-axis are not limited to three axes on a Cartesian coordinate system, and may be interpreted in a broad sense including them.
  • the x-axis, y-axis, and z-axis may be orthogonal to each other, but may refer to different directions that are not orthogonal to each other.
  • a specific process sequence may be performed different from the described sequence.
  • two processes described in succession may be performed substantially simultaneously, or may be performed in an order opposite to the order described.
  • FIG. 1 shows a method for manufacturing a abdominal cavity structure according to an embodiment of the present invention
  • FIGS. 2 and 3 schematically show a state of acquiring an abdominal cavity image according to an embodiment of the present invention
  • FIG. 4 is one of the present invention Shows the baseline (SL) obtained in accordance with the embodiment
  • Figures 5 and 6 shows the abdominal cavity structure 10 according to an embodiment of the present invention
  • Figure 7 is a third structure according to an embodiment of the present invention ( 300) is shown.
  • the method of manufacturing a abdominal cavity structure according to an embodiment of the present invention may be a method of manufacturing a structure that mimics the abdominal cavity structure of a subject. More specifically, the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention is a method of manufacturing a structure that mimics the abdominal cavity structure of a prospective transplant recipient who wants to receive a liver transplant, wherein the abdominal cavity structure 10 is a transplant recipient in which the transplanted liver is located may include the upper abdomen of
  • the method for manufacturing a abdominal cavity structure includes the steps of obtaining an abdominal cavity structure image through computer imaging (S100), and converting the obtained image into a plurality of regions (A)
  • the step of dividing (S200), the step of obtaining a plurality of reference lines (SL) in the plurality of divided regions (S300), and the step of modeling the plurality of first structures based on the obtained plurality of reference lines (S400) may include
  • an image of the abdominal cavity structure of the subject is acquired. More specifically, as shown in FIGS. 2 and 3 , computerized imaging is performed to confirm the location of the abdominal cavity structure and major body structures of the subject who wants to receive a liver transplant.
  • the computer image capturing technique is not particularly limited.
  • an image of the abdominal cavity structure of the subject may be acquired using computed tomography (CT) or magnetic resonance imaging (MRI).
  • the acquired abdominal structure image may be an image of a cross-section of the abdominal cavity (sagittal plane, coronal plane, transvers plane, or a cross-section inclined at a predetermined angle, etc.).
  • the acquired abdominal cavity structure image may be an image obtained by implementing these cross-sectional images in three dimensions.
  • the acquired abdominal cavity structure image may be an image capable of identifying the location of the subject's liver.
  • the acquired abdominal cavity structure image may be an image capable of identifying the location of the subject's chest and other major body structures.
  • the acquired abdominal structure image may be an image capable of identifying positions of the right kidney (K1), the left kidney (K2), and the inferior vena cava (IVC).
  • the acquired abdominal cavity structure image may be an image capable of identifying the positions of major body structures located in the vicinity with respect to the position of the liver.
  • the acquired abdominal structure image is divided into a plurality of regions (A). More specifically, as shown in FIG. 2 , the acquired abdominal cavity structure image may be divided into eight regions from the first region A1 to the eighth region A8 in the height direction. The number of the divided regions A is not particularly limited.
  • the step of dividing the acquired abdominal cavity structure image into a plurality of regions (A) may divide the acquired abdominal cavity image so that major body structures of the subject are identified in the plurality of regions (A).
  • the main body structure may be a body structure located around the subject's liver.
  • at least one of a diaphragm, a rib cage (thorax), an inferior vena cava, and a kidney (kidney) is the plurality of
  • the acquired abdominal structure image may be segmented so as to be identified in the region (A) of the dog.
  • a liver removed from a donor's body must be transplanted to an appropriate part of the subject's body.
  • the position, size, and shape of the surrounding body structures surrounding the liver must be identified in advance.
  • the main body structures surrounding the liver include the diaphragm located above the liver, the rib cage (more specifically, the ribs) located below and outside the liver, the inferior vena cava located on the medial side and center of the liver, and the lower part of the liver There is a kidney located in Therefore, in the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the acquired abdominal cavity structure image is divided into a plurality of regions (A), and in the plurality of regions (A), at least one of the diaphragm, the rib cage, the inferior vena cava, and the kidney By identifying any one, it is possible to accurately grasp the location of the liver transplantation in the subject's body in advance.
  • the reference line SL is a line extracted from the plurality of regions A, and may serve as a reference for modeling the abdominal cavity structure 10 .
  • the plurality of reference lines SL in the acquiring of the plurality of reference lines SL, may be disposed to be spaced apart from each other in one direction based on the divided plurality of areas A. As shown in FIG. In an embodiment, in the acquiring of the plurality of reference lines SL, the plurality of reference lines SL may be a plurality of profiles corresponding to the inner wall of the abdominal cavity.
  • a reference line SL is obtained from each of the plurality of divided regions A.
  • a first reference line is obtained in the first area A1
  • a second reference line is obtained in the second area A2
  • a third reference line is obtained in the third area A3.
  • obtain, obtain a fourth reference line in a fourth area A4 obtain a fifth reference line in a fifth area A5, obtain a sixth reference line in a sixth area A6, and obtain a sixth reference line in a seventh area A7 )
  • a seventh reference line may be obtained
  • an eighth reference line may be obtained from the eighth area A8.
  • first to eighth reference lines may be spaced apart from each other by a predetermined interval.
  • first to eighth reference lines may correspond to the profile of the inner wall of the abdominal cavity to be modeled.
  • the distance between the reference lines SL may be varied according to the thickness of the abdominal cavity identified in the acquired image.
  • the interval between the reference lines SL may be 2 cm to 3.5 cm.
  • intervals between the plurality of obtained reference lines SL may not necessarily match.
  • the interval between the first reference line and the second reference line may be different from the interval between the second reference line and the third reference line.
  • the reference for acquiring the reference line SL may be the thickness of the abdominal cavity identified in the acquired abdominal cavity structure image.
  • the interval between the reference lines SL may be wider. Conversely, when the thickness of the abdominal cavity identified in the acquired abdominal cavity structure image changes rapidly, the interval between the reference lines SL may be narrower.
  • a plurality of reference lines SL may be arranged such that the reference lines SL are more densely focused on the inflection point of the thickness of the abdominal cavity identified in the acquired abdominal cavity structure image.
  • the thickness of the abdominal cavity may mean a cross-sectional thickness in the acquired abdominal cavity structure image.
  • the number of the acquired reference lines SL may not necessarily correspond to the number of the divided regions A.
  • two or more reference lines SL may be obtained in the first area A1 , and no reference lines may be obtained in the second area A2 .
  • the reference for acquiring the reference line SL may be the thickness of the abdominal cavity identified from the acquired abdominal cavity structure image.
  • the plurality of baselines may overlap at least one of the diaphragm, the rib cage, the inferior vena cava, and the kidney on a cross-section of the acquired abdominal structure image.
  • FIG. 4 shows a state in which one of the plurality of obtained reference lines SL is viewed from a plane.
  • the reference line SL may represent a profile corresponding to the inner wall of the abdominal cavity, that is, a cross-section of the inner wall of the abdominal cavity.
  • main body structures S1 , S2 , S3 , and S4 may be disposed inside the reference line SL.
  • the plurality of acquired reference lines SL may be disposed to overlap at least one of the main body structures S1 , S2 , S3 and S4 .
  • the main body structures S1 , S2 , S3 and S4 may be at least one of the diaphragm, the rib cage, the inferior vena cava, and the kidney. Accordingly, in the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the reference line SL may be obtained in consideration of the location of the main body structure located around the liver of the subject.
  • the reference line SL is circular, this is only an example and the shape of the reference line SL may vary depending on the acquired abdominal cavity structure image, the number and spacing of the divided regions A, etc. .
  • the reference line SL is not necessarily a closed curve, but may be an open curve.
  • any one reference line SL and all of the main body structures S1 , S2 , S3 and S4 are shown to overlap, but the present invention is not limited thereto.
  • Some of the obtained reference lines SL may be disposed so as not to overlap the main body structures S1 , S2 , S3 and S4 . It is sufficient if the main body structures S1 , S2 , S3 , and S4 overlap with the reference line SL based on all of the obtained plurality of reference lines SL.
  • a plurality of first structures 100 are modeled based on the plurality of obtained reference lines SL.
  • the modeling of the plurality of first structures 100 may include manufacturing by stacking the plurality of obtained reference lines SL to have predetermined widths and widths. More specifically, the plurality of obtained reference lines SL become the center lines CL of the plurality of first structures 100 , and the first structure 100 having a cross-section of a rectangular parallelepiped shape may be modeled based on the obtained plurality of reference lines SL. In an embodiment, the first structure 100 may be manufactured by stacking around the reference line SL using a 3D printer.
  • the width and width of the first structure 100 are not particularly limited.
  • the width of the first structure 100 may be 2 mm, the width may be 3 mm to 4 mm.
  • the plurality of first structures 100 may have a circular cross-section with respect to the plurality of reference lines SL.
  • a plurality of first structures 100 may be obtained. More specifically, the plurality of first structures 100 is a total of eight (1a structures 100a, 1b structures 100b, 1c structures 100c, 1d structures 100d, 1e structures 100e). ), a 1f structure 100f, a 1g structure 100g, and a 1h structure 100h), and these first structures 100 may be disposed at predetermined intervals along the height direction.
  • the 1a structures 100a and 1b structures 100b may form a closed curve, and the remaining first structures 100 may form an open curve.
  • the spacing d between the structures 100 may be different from each other.
  • a distance between the 1a structure 100a and the 1b structure 100b and a distance between the 1b structure 100b and the 1c structure 100c may be different from each other.
  • the distance between the first structures 100 may vary depending on the obtained distance between the reference lines SL.
  • first structure 100 is eight in FIGS. 5 and 6 , the number is not particularly limited.
  • the number of first structures 100 may correspond to the number of reference lines SL.
  • the method for manufacturing a abdominal cavity structure according to the present invention may further include modeling the plurality of second structures 200 supporting each of the modeled plurality of first structures 100 ( S500 ).
  • At least one support point is set for each of the plurality of first structures 100 , and the second structure 200 is the first structure at the support point.
  • a support groove 210 corresponding to the curvature of 100 may be provided.
  • the second structure 200 is a structure that supports the first structure 100 , and at least one or more of the second structures 200 may be disposed for each of the first structures 100 .
  • the second structure 200 is disposed on one side and the other side for each first structure 100 , respectively, to support the first structure 100 .
  • the position at which the second structure 200 contacts the first structure 100 may be a position corresponding to the paracolic gutter on the outer surface and the inferior vena cava on the inner surface based on the position of the liver.
  • the second structure 200 is a rectangular parallelepiped-shaped member having a length L, and one end supporting the first structure 100 may be provided with a support groove 210 . More specifically, as shown in FIG. 7 , the support groove 210 may be formed by cutting a portion of a rectangular parallelepiped, and may include support guides 220 at both ends.
  • the bottom surface of the support groove 210 is shown to be inclined in FIG. 7 , this may vary depending on the shape of the first structure 100 supported by the second structure 200 . That is, the second structure 200 may have a shape corresponding to the curvature or outline of the first structure 100 based on a support point that is a position in contact with the first structure 100 . Similarly, the depth of the support groove 210 of the second structure 200 also varies depending on the curvature or outline of the first structure 100 at the position where the second structure 200 is in contact with the first structure 100 . can
  • the plurality of second structures 200 in the modeling of the plurality of second structures 200 , have a predetermined support surface and have different lengths depending on positions connected to the first structures 100 . It can be laminated to have a.
  • the second structure 200 may be manufactured by additive manufacturing using a 3D printer.
  • the plurality of second structures 200 may all have the same support surface (eg, the upper surface of the fourth structure 200 to be described later).
  • stacking may be manufactured to have different lengths depending on a location (support point) connected to the first structure 100 .
  • the method for manufacturing a abdominal cavity structure according to the present invention may further include modeling a plurality of third structures 300 supporting each of the modeled plurality of second structures 200 ( S600 ).
  • the plurality of second structures 200 are arranged to extend in one direction while supporting the plurality of first structures 100 .
  • the plurality of third structures 300 may be disposed at ends of the plurality of second structures 200 in one direction to support them.
  • the shape of the third structure 300 is not particularly limited, and for example, may be a cylindrical shape having an insertion groove 310 having a predetermined depth. One end of the plurality of second structures 200 may be inserted and supported in the insertion groove 310 .
  • the third structure 300 may be manufactured by additive manufacturing using a 3D printer.
  • the abdominal cavity structure 10 according to the present invention may further include a fourth structure 400 .
  • the fourth structure 400 may be a plate-shaped member having a support surface to support the plurality of third structures 300 .
  • the shape, size, and material of the fourth structure 400 are not particularly limited, and if a flat support surface capable of supporting the first structure 100 , the second structure 200 and the third structure 300 is provided, Suffice.
  • the fourth structure 400 may be a conventional acrylic plate.
  • FIG. 8 shows a liver transplantation operation using the abdominal cavity structure 10 according to an embodiment of the present invention.
  • the structure of the abdominal cavity around the liver of the subject can be simulated before the liver transplantation operation is performed.
  • the medical staff can compare the extracted liver with the abdominal cavity structure 10 and determine in advance how to proceed with the liver transplantation operation.
  • liver transplantation surgery is performed by checking in advance the size, shape, and structure of the subject's abdominal cavity, including major body structures important for liver transplantation. can be carried out more safely and accurately.
  • the abdominal cavity structure manufacturing method according to an embodiment of the present invention Using the abdominal cavity structure manufacturing method according to an embodiment of the present invention and the abdominal cavity structure 10 using the same, it is possible to determine in advance whether to proceed with the liver transplantation operation using the abdominal cavity structure 10 before the liver transplantation operation after the liver removal operation.
  • the excised liver and the abdominal cavity structure 10 are compared, and the excised liver is made into a reduced graft, or divided liver transplantation surgery is performed. You can decide whether to proceed or not.
  • the abdominal cavity structure manufacturing method and the abdominal cavity structure 10 using the same implement the abdominal cavity structure of the subject using 3D printing technology with a focus on the minimal major body structures that are important during liver transplantation, thereby reducing manufacturing costs and It is possible to accurately simulate the structure of the patient's abdominal cavity required for liver transplantation while reducing time.
  • connection or connection member of the lines between the components shown in the drawings exemplifies functional connections and/or physical or circuit connections, and in an actual device, various functional connections, physical connections that are replaceable or additional It may be expressed as a connection, or circuit connections.
  • connection, or circuit connections unless there is a specific reference such as "essential”, “importantly”, etc., it may not be a necessary component for the application of the present invention.
  • the present invention can be used in a method for manufacturing a abdominal cavity structure using 3D printing and an industry related to the abdominal cavity structure using the same.

Abstract

La présente invention concerne un procédé de fabrication d'une structure de cavité abdominale à l'aide d'une impression 3D et une structure de cavité abdominale l'utilisant. Le procédé de fabrication de cavité abdominale, selon un mode de réalisation de la présente invention, est un procédé de fabrication d'une structure de cavité abdominale à l'aide d'une impression 3D. Le procédé de fabrication de cavité abdominale comprend les étapes suivantes : l'acquisition d'une image de structure de cavité abdominale par tomographie par ordinateur ; la division de l'image acquise en multiples segments ; l'acquisition de multiples lignes de référence dans les multiples segments ; la modélisation de multiples premières structures sur la base des multiples lignes de référence acquises.
PCT/KR2021/013356 2020-10-05 2021-09-29 Procédé de fabrication d'une structure de cavité abdominale à l'aide d'une impression 3d et structure de cavité abdominale utilisant un tel procédé WO2022075656A1 (fr)

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KR10-2020-0128281 2020-10-05
KR1020200128281A KR102352844B1 (ko) 2020-10-05 2020-10-05 3d 프린팅을 이용한 복강 구조물 제조방법 및 이를 이용한 복강 구조물

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KR20160024894A (ko) * 2016-02-16 2016-03-07 최병억 영상기반의 환자 맞춤 의료형 보형물 제조 시스템 및 플랫폼
JP2018112646A (ja) * 2017-01-11 2018-07-19 村上 貴志 手術トレーニングシステム
KR20180124005A (ko) * 2018-11-13 2018-11-20 사회복지법인 삼성생명공익재단 측두골 모형 제작 방법 및 그 방법에 의하여 제작된 측두골 모형

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