WO2022075656A1

WO2022075656A1 - Method for manufacturing abdominal cavity structure by using 3d printing and abdominal cavity structure using same

Info

Publication number: WO2022075656A1
Application number: PCT/KR2021/013356
Authority: WO
Inventors: 유진수; 조재원; 최규성; 김종만; 김미승
Original assignee: 사회복지법인 삼성생명공익재단
Priority date: 2020-10-05
Filing date: 2021-09-29
Publication date: 2022-04-14
Also published as: KR102415254B1; KR20220045568A; KR102352844B1

Abstract

The present invention relates to a method for manufacturing an abdominal cavity structure by using 3D printing and an abdominal cavity structure using same. The abdominal cavity manufacturing method according to an embodiment of the present invention is a method for manufacturing an abdominal cavity structure by using 3D printing. The abdominal cavity manufacturing method comprises the steps of: acquiring an abdominal cavity structure image through computer tomography; dividing the acquired image into multiple segments; acquiring multiple reference lines in the multiple segments; and modeling multiple first structures on the basis of the acquired multiple reference lines.

Description

Abdominal cavity structure manufacturing method using 3D printing and abdominal cavity structure using same

The present invention relates to a method for manufacturing a abdominal cavity structure and a abdominal cavity structure using the same, and more particularly, to a method for manufacturing a abdominal cavity structure using 3D printing and a abdominal cavity structure manufactured accordingly.

When selecting a transplant recipient who will receive a liver from a donor, such as a brain dead, a decision is made by considering not only how urgently a liver transplant is needed, but also blood type and body size. At this time, there are cases in which surgery is performed without accurately determining the size or shape of the donor's liver. Alternatively, there is a case where the transplantation operation of a donor is performed in another hospital without a transplant recipient, and thus whether the liver is suitable for transplantation depends entirely on the judgment of the transplant surgeon. Due to this, there is a risk that the liver graft removed from the donor is too large or too small for the size of the recipient's abdominal cavity, and thus the transplantation fails.

The above-mentioned background art is technical information possessed by the inventor for the derivation of the present invention or acquired in the process of derivation of the present invention, and cannot necessarily be said to be a known technique disclosed to the general public prior to the filing of the present invention.

The present invention is to solve the above-mentioned problems, and provides a method for manufacturing an abdominal cavity structure using 3D printing and a method for manufacturing an abdominal cavity using the 3D printing, which implements the shape or size of the abdominal cavity of a transplant recipient as it is, so that a liver transplantation operation can be performed safely and efficiently can do.

However, these problems are exemplary, and the problems to be solved by the present invention are not limited thereto.

A method for manufacturing a abdominal cavity structure according to an embodiment of the present invention is a method for manufacturing a abdominal cavity structure using 3D printing, comprising the steps of obtaining an abdominal cavity structure image through computerized imaging, dividing the obtained image into a plurality of regions, the Acquiring a plurality of reference lines in a plurality of divided regions, and modeling a plurality of first structures based on the obtained plurality of reference lines.

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the step of dividing the image into a plurality of regions divides the image so that at least one of the diaphragm, rib cage, inferior vena cava and kidney is identified in the plurality of regions. can do.

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, in the step of obtaining the plurality of reference lines, the plurality of reference lines are spaced apart in one direction based on the divided plurality of regions, and on the inner wall of the abdominal cavity It may be a plurality of corresponding profiles.

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the obtaining of the plurality of reference lines may vary the number of the reference lines according to the thickness of the abdominal cavity identified in the acquired image.

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, in the step of acquiring the plurality of baselines, on the cross section of the image, the plurality of baselines overlap with at least one of the diaphragm, rib cage, inferior vena cava and kidney. can

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the modeling of the plurality of first structures may be manufactured by stacking the plurality of obtained reference lines to have a predetermined width and width.

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the method may further include modeling a plurality of second structures supporting each of the modeled plurality of first structures.

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the modeling of the plurality of second structures includes setting at least one or more support points for each of the plurality of first structures, and the second structure is the support point. It can be provided with a support groove corresponding to the curvature of the first structure in the.

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the modeling of the plurality of second structures includes the plurality of second structures having a predetermined support surface, and at a position connected to the first structure. Depending on the length, it can be laminated to have different lengths.

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the method may further include modeling a plurality of third structures supporting each of the modeled plurality of second structures.

In the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the plurality of third structures may include an insertion groove into which one end of the plurality of second structures is inserted.

Abdominal cavity structure according to another embodiment of the present invention, based on the abdominal cavity image obtained through computer imaging, corresponding to the inner wall profile of the abdominal cavity, a plurality of first structures disposed spaced apart by a predetermined interval in one direction, the It includes a plurality of second structures supporting each of the plurality of first structures, and a plurality of third structures supporting lower ends of the plurality of second structures and disposed on a fourth structure having a flat plate shape.

In the abdominal cavity structure according to another embodiment of the present invention, the plurality of first structures may be arranged to overlap at least one of the diaphragm, the rib cage, the inferior vena cava and the kidney in a cross-section based on the acquired abdominal cavity image. .

In the abdominal cavity structure according to another embodiment of the present invention, one end of the plurality of second structures is connected to the first structure, the other end is connected to the third structure, and one end is connected to the curvature of the first structure. A corresponding support groove may be provided.

In the abdominal cavity structure according to another embodiment of the present invention, the plurality of second structures may have a flat support surface at the other end, and may have different lengths depending on positions connected to the first structures.

In the abdominal cavity structure according to another embodiment of the present invention, the plurality of third structures may have an insertion groove into which one end of the plurality of second structures is inserted.

Other aspects, features and advantages other than those described above will become apparent from the following detailed description, claims and drawings for carrying out the invention.

Using the method for manufacturing an abdominal cavity structure according to an embodiment of the present invention and the abdominal cavity structure using the same, an abdominal cavity structure simulating the abdominal cavity structure of a subject, including major body structures located around the subject's liver, can be used for liver transplantation . Through this, it is possible to increase the probability of success of the liver transplantation surgery by comparing the extracted liver and the abdominal cavity structure to determine in advance how to proceed with the liver transplantation operation.

The abdominal cavity structure manufacturing method and the abdominal cavity structure using the same according to an embodiment of the present invention use 3D printing technology to simulate the abdominal cavity structure of a subject in consideration of the minimum major body structures to be considered during liver transplantation, thereby expediting liver transplantation surgery and can proceed accurately.

1 shows a method for manufacturing a abdominal cavity structure according to an embodiment of the present invention.

2 and 3 schematically show a state in which an abdominal cavity image is acquired according to an embodiment of the present invention.

4 shows a baseline obtained according to an embodiment of the present invention.

5 and 6 show a abdominal cavity structure according to an embodiment of the present invention.

7 shows a third structure according to an embodiment of the present invention.

8 shows a liver transplantation operation using an abdominal cavity structure according to an embodiment of the present invention.

Since the present invention can apply various transformations and can have various embodiments, specific embodiments are illustrated in the drawings and described in detail in the description of the invention. However, this is not intended to limit the present invention to specific embodiments, and should be understood to include all modifications, equivalents and substitutes included in the spirit and scope of the present invention. In the description of the present invention, even though shown in other embodiments, the same identification numbers are used for the same components.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings, and when described with reference to the drawings, the same or corresponding components are given the same reference numerals, and the overlapping description thereof will be omitted. .

In the following embodiments, terms such as first, second, etc. are used for the purpose of distinguishing one component from another, not in a limiting sense.

In the following examples, the singular expression includes the plural expression unless the context clearly dictates otherwise.

In the following embodiments, terms such as include or have means that the features or components described in the specification are present, and the possibility that one or more other features or components will be added is not excluded in advance.

In the drawings, the size of the components may be exaggerated or reduced for convenience of description. For example, since the size and thickness of each component shown in the drawings are arbitrarily indicated for convenience of description, the present invention is not necessarily limited to the illustrated bar.

In the following embodiments, the x-axis, the y-axis, and the z-axis are not limited to three axes on a Cartesian coordinate system, and may be interpreted in a broad sense including them. For example, the x-axis, y-axis, and z-axis may be orthogonal to each other, but may refer to different directions that are not orthogonal to each other.

In cases where certain embodiments may be implemented otherwise, a specific process sequence may be performed different from the described sequence. For example, two processes described in succession may be performed substantially simultaneously, or may be performed in an order opposite to the order described.

The terms used in the present application are only used to describe specific embodiments, and are not intended to limit the present invention. In the present application, terms such as “comprise” or “have” are intended to designate that a feature, number, step, operation, component, part, or combination thereof described in the specification exists, but one or more other features It should be understood that this does not preclude the existence or addition of numbers, steps, operations, components, parts, or combinations thereof.

1 shows a method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, FIGS. 2 and 3 schematically show a state of acquiring an abdominal cavity image according to an embodiment of the present invention, and FIG. 4 is one of the present invention Shows the baseline (SL) obtained in accordance with the embodiment, Figures 5 and 6 shows the abdominal cavity structure 10 according to an embodiment of the present invention, Figure 7 is a third structure according to an embodiment of the present invention ( 300) is shown.

The method of manufacturing a abdominal cavity structure according to an embodiment of the present invention may be a method of manufacturing a structure that mimics the abdominal cavity structure of a subject. More specifically, the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention is a method of manufacturing a structure that mimics the abdominal cavity structure of a prospective transplant recipient who wants to receive a liver transplant, wherein the abdominal cavity structure 10 is a transplant recipient in which the transplanted liver is located may include the upper abdomen of

1 to 7 , the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention includes the steps of obtaining an abdominal cavity structure image through computer imaging (S100), and converting the obtained image into a plurality of regions (A) The step of dividing (S200), the step of obtaining a plurality of reference lines (SL) in the plurality of divided regions (S300), and the step of modeling the plurality of first structures based on the obtained plurality of reference lines (S400) may include

First, an image of the abdominal cavity structure of the subject is acquired. More specifically, as shown in FIGS. 2 and 3 , computerized imaging is performed to confirm the location of the abdominal cavity structure and major body structures of the subject who wants to receive a liver transplant. Here, the computer image capturing technique is not particularly limited. For example, an image of the abdominal cavity structure of the subject may be acquired using computed tomography (CT) or magnetic resonance imaging (MRI).

In one embodiment, the acquired abdominal structure image may be an image of a cross-section of the abdominal cavity (sagittal plane, coronal plane, transvers plane, or a cross-section inclined at a predetermined angle, etc.). . Alternatively, the acquired abdominal cavity structure image may be an image obtained by implementing these cross-sectional images in three dimensions.

In an embodiment, the acquired abdominal cavity structure image may be an image capable of identifying the location of the subject's liver. In an embodiment, the acquired abdominal cavity structure image may be an image capable of identifying the location of the subject's chest and other major body structures. For example, as shown in FIG. 3 , the acquired abdominal structure image may be an image capable of identifying positions of the right kidney (K1), the left kidney (K2), and the inferior vena cava (IVC). In addition, although not shown in the drawings, the acquired abdominal cavity structure image may be an image capable of identifying the positions of major body structures located in the vicinity with respect to the position of the liver.

Next, the acquired abdominal structure image is divided into a plurality of regions (A). More specifically, as shown in FIG. 2 , the acquired abdominal cavity structure image may be divided into eight regions from the first region A1 to the eighth region A8 in the height direction. The number of the divided regions A is not particularly limited.

In an embodiment, the step of dividing the acquired abdominal cavity structure image into a plurality of regions (A) may divide the acquired abdominal cavity image so that major body structures of the subject are identified in the plurality of regions (A). Here, the main body structure may be a body structure located around the subject's liver. For example, in the step of dividing the acquired abdominal structure image into a plurality of regions (A), at least one of a diaphragm, a rib cage (thorax), an inferior vena cava, and a kidney (kidney) is the plurality of The acquired abdominal structure image may be segmented so as to be identified in the region (A) of the dog.

More specifically, in order to successfully perform a liver transplant, a liver removed from a donor's body must be transplanted to an appropriate part of the subject's body. For this, the position, size, and shape of the surrounding body structures surrounding the liver must be identified in advance. The main body structures surrounding the liver include the diaphragm located above the liver, the rib cage (more specifically, the ribs) located below and outside the liver, the inferior vena cava located on the medial side and center of the liver, and the lower part of the liver There is a kidney located in Therefore, in the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the acquired abdominal cavity structure image is divided into a plurality of regions (A), and in the plurality of regions (A), at least one of the diaphragm, the rib cage, the inferior vena cava, and the kidney By identifying any one, it is possible to accurately grasp the location of the liver transplantation in the subject's body in advance.

Next, a plurality of reference lines SL are obtained in the plurality of divided regions A. The reference line SL is a line extracted from the plurality of regions A, and may serve as a reference for modeling the abdominal cavity structure 10 .

In an embodiment, in the acquiring of the plurality of reference lines SL, the plurality of reference lines SL may be disposed to be spaced apart from each other in one direction based on the divided plurality of areas A. As shown in FIG. In an embodiment, in the acquiring of the plurality of reference lines SL, the plurality of reference lines SL may be a plurality of profiles corresponding to the inner wall of the abdominal cavity.

More specifically, a reference line SL is obtained from each of the plurality of divided regions A. For example, as shown in FIG. 2 , a first reference line is obtained in the first area A1, a second reference line is obtained in the second area A2, and a third reference line is obtained in the third area A3. obtain, obtain a fourth reference line in a fourth area A4, obtain a fifth reference line in a fifth area A5, obtain a sixth reference line in a sixth area A6, and obtain a sixth reference line in a seventh area A7 ), a seventh reference line may be obtained, and an eighth reference line may be obtained from the eighth area A8.

In addition, the first to eighth reference lines may be spaced apart from each other by a predetermined interval. In addition, the first to eighth reference lines may correspond to the profile of the inner wall of the abdominal cavity to be modeled.

In an embodiment, in the acquiring of the plurality of reference lines SL, the distance between the reference lines SL may be varied according to the thickness of the abdominal cavity identified in the acquired image. For example, the interval between the reference lines SL may be 2 cm to 3.5 cm.

That is, intervals between the plurality of obtained reference lines SL may not necessarily match. For example, the interval between the first reference line and the second reference line may be different from the interval between the second reference line and the third reference line. In this case, the reference for acquiring the reference line SL may be the thickness of the abdominal cavity identified in the acquired abdominal cavity structure image.

More specifically, when the thickness of the abdominal cavity identified in the acquired abdominal cavity structure image is maintained relatively constant, the interval between the reference lines SL may be wider. Conversely, when the thickness of the abdominal cavity identified in the acquired abdominal cavity structure image changes rapidly, the interval between the reference lines SL may be narrower. In an embodiment, a plurality of reference lines SL may be arranged such that the reference lines SL are more densely focused on the inflection point of the thickness of the abdominal cavity identified in the acquired abdominal cavity structure image.

In an embodiment, the thickness of the abdominal cavity may mean a cross-sectional thickness in the acquired abdominal cavity structure image.

As an embodiment, the number of the acquired reference lines SL may not necessarily correspond to the number of the divided regions A. For example, two or more reference lines SL may be obtained in the first area A1 , and no reference lines may be obtained in the second area A2 . Even in this case, the reference for acquiring the reference line SL may be the thickness of the abdominal cavity identified from the acquired abdominal cavity structure image.

In an embodiment, in the acquiring of the plurality of baselines SL, the plurality of baselines may overlap at least one of the diaphragm, the rib cage, the inferior vena cava, and the kidney on a cross-section of the acquired abdominal structure image.

More specifically, FIG. 4 shows a state in which one of the plurality of obtained reference lines SL is viewed from a plane. As described above, the reference line SL may represent a profile corresponding to the inner wall of the abdominal cavity, that is, a cross-section of the inner wall of the abdominal cavity. Also, main body structures S1 , S2 , S3 , and S4 may be disposed inside the reference line SL.

In other words, when viewed in a cross-section of the acquired abdominal cavity structure image, the plurality of acquired reference lines SL may be disposed to overlap at least one of the main body structures S1 , S2 , S3 and S4 . In addition, the main body structures S1 , S2 , S3 and S4 may be at least one of the diaphragm, the rib cage, the inferior vena cava, and the kidney. Accordingly, in the method for manufacturing a abdominal cavity structure according to an embodiment of the present invention, the reference line SL may be obtained in consideration of the location of the main body structure located around the liver of the subject.

Although it is shown in FIG. 4 that the reference line SL is circular, this is only an example and the shape of the reference line SL may vary depending on the acquired abdominal cavity structure image, the number and spacing of the divided regions A, etc. . In addition, the reference line SL is not necessarily a closed curve, but may be an open curve.

In FIG. 4 , any one reference line SL and all of the main body structures S1 , S2 , S3 and S4 are shown to overlap, but the present invention is not limited thereto. Some of the obtained reference lines SL may be disposed so as not to overlap the main body structures S1 , S2 , S3 and S4 . It is sufficient if the main body structures S1 , S2 , S3 , and S4 overlap with the reference line SL based on all of the obtained plurality of reference lines SL.

Next, a plurality of first structures 100 are modeled based on the plurality of obtained reference lines SL.

As an embodiment, the modeling of the plurality of first structures 100 may include manufacturing by stacking the plurality of obtained reference lines SL to have predetermined widths and widths. More specifically, the plurality of obtained reference lines SL become the center lines CL of the plurality of first structures 100 , and the first structure 100 having a cross-section of a rectangular parallelepiped shape may be modeled based on the obtained plurality of reference lines SL. In an embodiment, the first structure 100 may be manufactured by stacking around the reference line SL using a 3D printer.

The width and width of the first structure 100 are not particularly limited. For example, the width of the first structure 100 may be 2 mm, the width may be 3 mm to 4 mm.

In another embodiment, the plurality of first structures 100 may have a circular cross-section with respect to the plurality of reference lines SL.

In an embodiment, as shown in FIGS. 5 and 6 , a plurality of first structures 100 may be obtained. More specifically, the plurality of first structures 100 is a total of eight (1a structures 100a, 1b structures 100b, 1c structures 100c, 1d structures 100d, 1e structures 100e). ), a 1f structure 100f, a 1g structure 100g, and a 1h structure 100h), and these first structures 100 may be disposed at predetermined intervals along the height direction.

In addition, among the first structures 100 , the 1a structures 100a and 1b structures 100b may form a closed curve, and the remaining first structures 100 may form an open curve.

In an embodiment, the spacing d between the structures 100 may be different from each other. For example, a distance between the 1a structure 100a and the 1b structure 100b and a distance between the 1b structure 100b and the 1c structure 100c may be different from each other. The distance between the first structures 100 may vary depending on the obtained distance between the reference lines SL.

Although it is shown that the first structure 100 is eight in FIGS. 5 and 6 , the number is not particularly limited. For example, the number of first structures 100 may correspond to the number of reference lines SL.

In one embodiment, the method for manufacturing a abdominal cavity structure according to the present invention may further include modeling the plurality of second structures 200 supporting each of the modeled plurality of first structures 100 ( S500 ).

In one embodiment, in the modeling of the plurality of second structures 200 , at least one support point is set for each of the plurality of first structures 100 , and the second structure 200 is the first structure at the support point. A support groove 210 corresponding to the curvature of 100 may be provided.

More specifically, the second structure 200 is a structure that supports the first structure 100 , and at least one or more of the second structures 200 may be disposed for each of the first structures 100 . For example, as shown in FIGS. 5 to 7 , the second structure 200 is disposed on one side and the other side for each first structure 100 , respectively, to support the first structure 100 . can

In one embodiment, the position at which the second structure 200 contacts the first structure 100 may be a position corresponding to the paracolic gutter on the outer surface and the inferior vena cava on the inner surface based on the position of the liver.

In one embodiment, the second structure 200 is a rectangular parallelepiped-shaped member having a length L, and one end supporting the first structure 100 may be provided with a support groove 210 . More specifically, as shown in FIG. 7 , the support groove 210 may be formed by cutting a portion of a rectangular parallelepiped, and may include support guides 220 at both ends.

Although the bottom surface of the support groove 210 is shown to be inclined in FIG. 7 , this may vary depending on the shape of the first structure 100 supported by the second structure 200 . That is, the second structure 200 may have a shape corresponding to the curvature or outline of the first structure 100 based on a support point that is a position in contact with the first structure 100 . Similarly, the depth of the support groove 210 of the second structure 200 also varies depending on the curvature or outline of the first structure 100 at the position where the second structure 200 is in contact with the first structure 100 . can

In one embodiment, in the modeling of the plurality of second structures 200 , the plurality of second structures 200 have a predetermined support surface and have different lengths depending on positions connected to the first structures 100 . It can be laminated to have a. In an embodiment, the second structure 200 may be manufactured by additive manufacturing using a 3D printer.

More specifically, as shown in FIG. 5 , the plurality of second structures 200 may all have the same support surface (eg, the upper surface of the fourth structure 200 to be described later). In addition, using the support surface as a stacking base, stacking may be manufactured to have different lengths depending on a location (support point) connected to the first structure 100 .

In one embodiment, the method for manufacturing a abdominal cavity structure according to the present invention may further include modeling a plurality of third structures 300 supporting each of the modeled plurality of second structures 200 ( S600 ).

More specifically, as shown in FIGS. 5 to 7 , the plurality of second structures 200 are arranged to extend in one direction while supporting the plurality of first structures 100 . The plurality of third structures 300 may be disposed at ends of the plurality of second structures 200 in one direction to support them.

The shape of the third structure 300 is not particularly limited, and for example, may be a cylindrical shape having an insertion groove 310 having a predetermined depth. One end of the plurality of second structures 200 may be inserted and supported in the insertion groove 310 .

In an embodiment, the third structure 300 may be manufactured by additive manufacturing using a 3D printer.

In an embodiment, the abdominal cavity structure 10 according to the present invention may further include a fourth structure 400 .

More specifically, as shown in FIG. 5 , the fourth structure 400 may be a plate-shaped member having a support surface to support the plurality of third structures 300 . The shape, size, and material of the fourth structure 400 are not particularly limited, and if a flat support surface capable of supporting the first structure 100 , the second structure 200 and the third structure 300 is provided, Suffice. For example, the fourth structure 400 may be a conventional acrylic plate.

8 shows a liver transplantation operation using the abdominal cavity structure 10 according to an embodiment of the present invention.

As shown in FIG. 8 , through the method for manufacturing the abdominal cavity structure according to the present invention and the abdominal cavity structure 10 using the same, the structure of the abdominal cavity around the liver of the subject can be simulated before the liver transplantation operation is performed. Through this, the medical staff can compare the extracted liver with the abdominal cavity structure 10 and determine in advance how to proceed with the liver transplantation operation.

Using the method for manufacturing an abdominal cavity structure according to an embodiment of the present invention and the abdominal cavity structure 10 using the same, liver transplantation surgery is performed by checking in advance the size, shape, and structure of the subject's abdominal cavity, including major body structures important for liver transplantation. can be carried out more safely and accurately.

Using the abdominal cavity structure manufacturing method according to an embodiment of the present invention and the abdominal cavity structure 10 using the same, it is possible to determine in advance whether to proceed with the liver transplantation operation using the abdominal cavity structure 10 before the liver transplantation operation after the liver removal operation.

Using the method for manufacturing the abdominal cavity structure according to an embodiment of the present invention and the abdominal cavity structure 10 using the same, the excised liver and the abdominal cavity structure 10 are compared, and the excised liver is made into a reduced graft, or divided liver transplantation surgery is performed. You can decide whether to proceed or not.

The abdominal cavity structure manufacturing method and the abdominal cavity structure 10 using the same according to an embodiment of the present invention implement the abdominal cavity structure of the subject using 3D printing technology with a focus on the minimal major body structures that are important during liver transplantation, thereby reducing manufacturing costs and It is possible to accurately simulate the structure of the patient's abdominal cavity required for liver transplantation while reducing time.

As described above, the present invention has been described with reference to the embodiment shown in the drawings, but this is only an example. Those of ordinary skill in the art can fully understand that various modifications and equivalent other embodiments are possible from the embodiments. Therefore, the true technical protection scope of the present invention should be determined based on the appended claims.

Specific technical content described in the embodiment is an embodiment and does not limit the technical scope of the embodiment. In order to concisely and clearly describe the description of the invention, descriptions of conventional general techniques and configurations may be omitted. In addition, the connection or connection member of the lines between the components shown in the drawings exemplifies functional connections and/or physical or circuit connections, and in an actual device, various functional connections, physical connections that are replaceable or additional It may be expressed as a connection, or circuit connections. In addition, unless there is a specific reference such as "essential", "importantly", etc., it may not be a necessary component for the application of the present invention.

In the description and claims, "above" or similar referents may refer to both the singular and the plural unless otherwise specified. In addition, when a range is described in the examples, it includes inventions to which individual values falling within the range are applied (unless there is a description to the contrary), and each individual value constituting the range is described in the description of the invention. same. In addition, the steps constituting the method according to the embodiment may be performed in an appropriate order unless the order is explicitly stated or there is no description to the contrary. The embodiments are not necessarily limited according to the order of description of the above steps. The use of all examples or exemplary terminology (eg, etc.) in the embodiment is merely for describing the embodiment in detail, and unless it is limited by the claims, the scope of the embodiment is limited by the examples or exemplary terminology. it is not In addition, those skilled in the art will appreciate that various modifications, combinations, and changes can be made in accordance with design conditions and factors within the scope of the appended claims or their equivalents.

The present invention can be used in a method for manufacturing a abdominal cavity structure using 3D printing and an industry related to the abdominal cavity structure using the same.

Claims

As a method for manufacturing a abdominal cavity structure using 3D printing,

acquiring an abdominal structure image through computerized imaging;

dividing the acquired image into a plurality of regions;

acquiring a plurality of reference lines in the plurality of divided regions; and

Based on the obtained plurality of reference lines, modeling a plurality of first structures; Containing, a method of manufacturing a abdominal cavity structure.
According to claim 1,

The step of dividing the image into a plurality of regions

A method of segmenting the image so that at least one of the diaphragm, the rib cage, the inferior vena cava and the kidney is identified in the plurality of regions.
According to claim 1,

In the step of acquiring the plurality of reference lines

The plurality of reference lines are spaced apart in one direction based on the divided plurality of regions, and are a plurality of profiles corresponding to the inner wall of the abdominal cavity, a method for manufacturing a abdominal cavity structure.
According to claim 1,

The step of acquiring the plurality of baselines

According to the thickness of the abdominal cavity identified in the acquired image, the number of the reference lines is varied, a method for manufacturing a abdominal cavity structure.
3. The method of claim 2,

In the step of acquiring the plurality of reference lines

On the cross-section of the image, the plurality of baselines overlap at least one of the diaphragm, the rib cage, the inferior vena cava, and the kidney.
According to claim 1,

The step of modeling the plurality of first structures is

A method for manufacturing a laminated structure in which the obtained plurality of reference lines have a predetermined width and width.
According to claim 1,

Further comprising the step of modeling a plurality of second structures supporting each of the modeled plurality of first structures, the method of manufacturing a abdominal cavity structure.
8. The method of claim 7,

The step of modeling the plurality of second structures is

At least one support point is set for each of the plurality of first structures, and the second structure has a support groove corresponding to the curvature of the first structure at the support point.
8. The method of claim 7,

The step of modeling the plurality of second structures is

Wherein the plurality of second structures are provided with a predetermined support surface, and laminated manufacturing to have different lengths depending on a position connected to the first structure, a method for manufacturing a abdominal structure.
8. The method of claim 7,

Further comprising the step of modeling a plurality of third structures supporting each of the modeled plurality of second structures, the method of manufacturing a abdominal cavity structure.
11. The method of claim 10,

The plurality of third structures

A method of manufacturing a abdominal cavity structure having an insertion groove into which one end of the plurality of second structures is inserted.
a plurality of first structures corresponding to the inner wall profile of the abdominal cavity based on the abdominal cavity image obtained through computer imaging, and spaced apart from each other by a predetermined interval in one direction;

a plurality of second structures each supporting the plurality of first structures; and

Supporting the lower ends of the plurality of second structures, a plurality of third structures disposed on the fourth structure in the form of a flat plate; including, the abdominal cavity structure.
13. The method of claim 12,

The plurality of first structures

Based on the acquired abdominal cavity image, the diaphragm, the rib cage, the abdominal cavity structure is arranged to overlap with at least one of the inferior vena cava and the kidney on a cross-section.
13. The method of claim 12,

The plurality of second structures

One end is connected to the first structure, the other end is connected to the third structure, the abdominal cavity structure having a support groove corresponding to the curvature of the first structure at the one end.
13. The method of claim 12,

The plurality of second structures

Having a flat support surface at the other end, and having a different length depending on the position connected to the first structure, the abdominal cavity structure.
13. The method of claim 12,

The plurality of third structures

An abdominal cavity structure having an insertion groove into which one end of the plurality of second structures is inserted.