WO2022070460A1 - Automatic analysis device - Google Patents

Automatic analysis device Download PDF

Info

Publication number
WO2022070460A1
WO2022070460A1 PCT/JP2021/007489 JP2021007489W WO2022070460A1 WO 2022070460 A1 WO2022070460 A1 WO 2022070460A1 JP 2021007489 W JP2021007489 W JP 2021007489W WO 2022070460 A1 WO2022070460 A1 WO 2022070460A1
Authority
WO
WIPO (PCT)
Prior art keywords
reagent
consumables
unit
automatic analyzer
analysis
Prior art date
Application number
PCT/JP2021/007489
Other languages
French (fr)
Japanese (ja)
Inventor
夏美 磯部
真章 近久
Original Assignee
株式会社日立ハイテク
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社日立ハイテク filed Critical 株式会社日立ハイテク
Priority to JP2022553441A priority Critical patent/JP7397216B2/en
Publication of WO2022070460A1 publication Critical patent/WO2022070460A1/en

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor

Definitions

  • the present invention relates to an automatic analyzer that automatically analyzes components such as blood.
  • Patent Document 1 includes a reagent storage in which the reagent containers are stored. It has a plurality of modules for analyzing the components of the reaction solution produced by reacting the reagent dispensed from the reagent container with the sample, and further has a control means and a transport means, and the control means is the first. It has a storage unit for storing the extraction condition 1 and the second extraction condition, and transports the reagent storage containing the reagent container corresponding to the first extraction condition from the reagent storage of the desired module being analyzed or to be analyzed.
  • a reagent container corresponding to the second extraction condition is searched from the reagent storage other than the desired module as a transport target. It is described that the transport means transports the transport target to the transport destination in response to the search for the transport destination and the transport target.
  • Patent Document 2 describes a first reagent disk, a second reagent disk, and a first reagent disk on which a reagent container containing a reagent used for a reaction is placed. It has a reagent transfer mechanism for transporting the reagent container between the second reagent disk, and the judgment unit and drive control unit of the computer first use the reagent transfer mechanism to transfer the reagent container installed on the second reagent disk. After performing at least quality control measurement among calibration and quality control measurement using the reagent transferred to the reagent disk and held in the reagent container transferred to the first reagent disk, the reagent is transferred using the reagent transfer mechanism. It is stated that the container should be returned to the second reagent disc.
  • the automatic analyzer dispenses a sample such as blood or urine from the sample container to the reaction vessel, further dispenses the reagent from the reagent container to the reaction vessel, and measures a mixed solution of the sample and the reagent by a measuring means such as a photometric meter. It is a device that measures and performs qualitative or quantitative analysis.
  • the reagent container used in the automated analyzer is installed in the reagent storage section inside the device in advance, and information including the remaining amount and expiration date is managed.
  • an apparatus having a function of automatically installing a reagent container in a reagent storage container in the apparatus has been put on the market in order to reduce the reagent exchange work by the user.
  • Patent Document 1 described above discloses that a reagent container is transported from a reagent storage section of another module to a reagent storage section of a module in which a reagent is desired, using a reagent transport section.
  • the reagent stored in the first reagent storage unit is transported to the second reagent storage unit using the above-mentioned reagent transport unit, and after calibration or quality control measurement is performed, the reagent is transferred to the second reagent storage unit.
  • a technique for returning to the first reagent storage unit using the above-mentioned reagent transport unit is disclosed.
  • consumables such as detergents used during analysis operation and equipment maintenance operation may also be stored in the reagent storage section inside the equipment in the same way as reagents.
  • the mechanism that can access the reagent storage unit is often limited due to its hardware restrictions, and in an automated analyzer having multiple reagent storage units in one module, it is assumed that the same reagent or detergent is a consumable item. However, it had to be installed in all reagent storages in order to be used in a mechanism to access all consumables.
  • the present invention has been made in view of the above, and in an automatic analyzer provided with a reagent transport unit and a plurality of reagent storage units, it is possible to reduce the operation load of the user and to mount the reagent storage unit efficiently. Provide an automatic analyzer that can improve.
  • the present invention includes a plurality of means for solving the above problems, and to give an example thereof, a plurality of reagent disks arranged in one module, each of which operates in parallel, and the reagent disk.
  • Consumables or equipment maintenance parts required for storable analysis are transported from the installation position in the equipment to the reagent discs, and the transport unit is moved between the plurality of reagent discs, and the consumables or the equipment maintenance.
  • a control unit that executes movement control to move a component from the reagent disk having the consumable item or the device maintenance component to a reagent disk subject to operation planning that does not have the consumable item or the device maintenance component. It is characterized by having.
  • FIG. 1 shows schematic the whole structure of the automatic analyzer of Example 1 of this invention. It is a figure which shows schematic the soft structure of the control part in the automatic analyzer of Example 1.
  • FIG. It is a flowchart which shows the creation procedure of the control plan which paralleled the reagent movement in the automatic analyzer of Example 1.
  • FIG. It is a figure which shows an example of the consumables management information in the automatic analyzer of Example 1.
  • FIG. It is a figure which shows an example of the consumables management screen in the automatic analyzer of Example 1.
  • FIG. shows another example of the consumables management screen in the automatic analyzer of Example 1.
  • FIG. It is a figure which shows the device maintenance execution screen example in the automatic analyzer of Example 2 of this invention.
  • FIG. shows schematic the soft structure of the control part in the automatic analyzer of Example 2.
  • FIG. It is a flowchart which shows the creation procedure of the apparatus maintenance control plan which includes the reagent movement in the automatic analyzer of Example 2.
  • FIG. is a flowchar
  • FIG. 1 is a diagram schematically showing the overall configuration of the automated analyzer of the first embodiment
  • FIG. 2 is a diagram schematically showing the soft structure of the control unit
  • FIG. 3 is a procedure for creating a control plan in which reagent movements are arranged in parallel.
  • FIG. 4 is a diagram showing an example of consumables management information
  • FIG. 5 is a diagram showing an example of a consumables management screen
  • FIG. 6 is a diagram showing another example of the consumables management screen.
  • the automatic analyzer 100 shown in FIG. 1 includes a plurality of reagent disks 101a, 101b, a plurality of reagent dispensing probes 103a, 103b, 103c, 103d, a reaction disk 102, a sample dispensing probe 104a, 104b, and a measuring unit (light source 105, It is mainly composed of a multi-wavelength photometer 106), a reagent loading / unloading area 109, a reagent transporting mechanism 108, a sample transporting mechanism 110, a control unit 119, a display unit 111, an operation unit 117, an input unit 118, and the like.
  • the reaction disk 102 includes a plurality of reaction containers 115 for reacting a sample and a reagent in a circular shape, and the reaction disk 102 rotates to move the reaction container 115 to a predetermined position on the circumference.
  • the sample dispensing probes 104a and 104b can rotate and move up and down, and are carried into the automatic analyzer from the sample carrying mechanism (not shown), and a predetermined amount of sample is taken from the sample container 112 carried by the sample carrying mechanism 110. Is sucked and discharged as a sample to the reaction disk 102.
  • the reagent disks 101a and 101b can hold a plurality of reagent containers 113a and 113b in a circular shape, and serve as a cold storage for storing the plurality of reagent containers 113a and 113b at a constant temperature. Also has.
  • the reagent discs 101a and 101b rotate to move the reagent containers 113a and 113b to predetermined positions on the circumference.
  • Reagent containers 113a and 113b contain reagents used for analysis and detergents used for cleaning each mechanism in the automatic analyzer 100.
  • two reagent disks 101a and 101b are arranged in one module, and each of them operates in parallel. Further, the reagent disks 101a and 101b are connected to the reagent loading / unloading area 109 via the reagent transporting mechanism 108 which can transport and move the reagent containers 113a and 113b, respectively, and can be loaded / unloaded from each other.
  • the reagent transfer mechanism 108 is a consumable or equipment maintenance component that can be stored in the reagent disks 101a and 101b and is necessary for analysis.
  • the reagent containers 113a and 113b containing the reagents used for analysis are used, or after analysis.
  • the cleaning container containing the cleaning liquid to be used is transported from the reagent loading / unloading area 109 to the reagent discs 101a and 101b, and is also moved between the plurality of reagent discs 101a and 101b.
  • the exchange of the reagent containers 113a, 113b and the like between the reagent discs 101a and 101b is "movement", and the reagent containers 113a, 113b and the like from the reagent container installation area 114 to the reagent discs 101a and 101b are used.
  • Communication is defined as "transportation”.
  • Reagent dispensing probes 103a and 103b are provided between the reagent disk 101a and the reaction disk 102, and reagent dispensing probes 103c and 103d are provided between the reagent disk 101b and the reaction disk 102, and they are connected to each other.
  • a predetermined amount of reagent is dispensed from the reagent containers 113a and 113b in the reagent disks 101a and 101b, and discharged to the reaction container 115.
  • a light source 105, a multi-wavelength photometer 106, and a reaction vessel cleaning mechanism 107 are further provided around the reaction disk 102 to measure the absorbance of the mixture of the sample and the reagent in the reaction vessel and perform cleaning.
  • the operation necessary for the subsequent analysis is carried out without interruption. Therefore, depending on which of the plurality of sample dispensing probes 104a and 104b was used for dispensing, that is, which reaction container 115 on the reaction disk 102 the sample was added to, the reagent container that can be used at a certain point in the subsequent analysis operation.
  • 113a and 113b are limited. Specifically, it is limited to those in which any of the corresponding reagent dispensing probes 103a, 103b, 103c, 103d at that time is loaded on the accessible reagent disks 101a, 101b.
  • the control unit 119 receives the sample information associated with the sample container 112 and the request information input by the input unit 118 from the operation unit 117 composed of a computer equipped with a CPU and a memory, and determines the operation plan of the mechanism. Create and control the mechanism.
  • control unit 119 transmits the measurement result acquired from the measurement unit to the operation unit 117.
  • the operation unit performs arithmetic processing from the received measurement result, calculates the concentration of the designated component in the sample, and displays it on the display unit 111.
  • control unit 119 operates without consumables or equipment maintenance parts from the reagent disks 101a and 101b having consumables or equipment maintenance parts.
  • the movement control for moving to the reagent disks 101a and 101b to be planned is executed.
  • consumables or equipment maintenance parts are complemented among the plurality of reagent disks 101a and 101b. The details will be described later.
  • the operation unit 117 and the control unit 119 are connected to each mechanism in the automatic analyzer 100 by wired or wireless network lines 116a and 116b.
  • These operation units 117 and control units 119 may be realized by using a general-purpose computer, or may be realized as a function of a program executed on the computer.
  • the processing carried by them may be stored as a program code in a recording unit such as a memory, and may be realized by executing each program code by a processor such as a CPU (Central Processing Unit). It may be configured by hardware such as a dedicated circuit board.
  • a processor such as a CPU (Central Processing Unit). It may be configured by hardware such as a dedicated circuit board.
  • the display unit 111 is a part on which various screens such as an operation screen for ordering measurement items to be measured for a sample to be measured, a screen for confirming the measurement result, and the like are displayed, and is composed of a liquid crystal display or the like. It does not have to be a liquid crystal display, and may be replaced with a printer or the like, and a display and a printer or the like can be configured to form a touch panel type display that also serves as an input unit 118, which will be described later.
  • the input unit 118 is a part for inputting various parameters and settings, measurement results, measurement request information, analysis start / stop instructions, etc. based on the operation screen displayed on the display unit 111, such as a keyboard and a mouse. Consists of.
  • FIG. 2 is a diagram schematically showing the soft structure of the control unit 119 of the automatic analyzer shown in FIG. 1, and the control unit 200 of FIG. 2 is a part of the control unit 119 of FIG.
  • the control unit 200 of this embodiment has a receiving unit 202, a transmitting unit 203, an analysis information holding unit 204, a consumables information holding unit 205, a planning execution unit 206, and an analysis operation as software functions related to the control of the reagent transport mechanism 108. It includes a planning unit 207, a reagent moving operation planning unit 208, a control information holding unit 209, a control execution unit 210, and a mechanism control unit 211a, 211b, 211c.
  • the analysis information holding unit 204 holds information necessary for performing the analysis operation input and set from the operation unit 201 via the receiving unit 202.
  • the information in the analysis information holding unit 204 includes the consumables information used for the analysis and is referred to by the planning execution unit 206.
  • the consumables information holding unit 205 holds a list of consumables information that can be used for the analysis operation, and information on whether or not the reagent disks 101a and 101b can be moved.
  • each information is edited by the receiving unit 202 to the control executing unit 210, and is transmitted to the operating unit 201 via the transmitting unit 203. Further, the information of the consumables information holding unit 205 is referred to by the planning execution unit 206.
  • the planning execution unit 206 has an analysis operation planning unit 207 and a reagent transfer operation planning unit 208, and refers to and analyzes information related to the analysis of the above-mentioned analysis information holding unit 204 and the above-mentioned consumables information holding unit 205.
  • the operation planning unit 207 plans the analysis operation
  • the reagent transfer operation planning unit 208 plans the reagent transfer operation.
  • the execution results of the analysis operation planning unit 207 and the reagent movement operation planning unit 208 are held in the control information holding unit 209 as control information of each mechanism.
  • the details of the planning logic used in the above planning execution will be described in detail later with reference to FIGS. 3 and later.
  • the control execution unit 210 outputs control instructions to the reagent transfer mechanism control unit 211a, the reagent disk control unit 211b, and the reagent probe control unit 211c based on the control information held in the control information holding unit 209.
  • the reagent transfer mechanism control unit 211a has the reagent transfer mechanism 108
  • the reagent disk control unit 211b has the reagent disks 101a and 101b
  • the reagent probe control unit 211c has the reagent dispensing probes 103a, 103b, 103c and 103d, respectively, as instructed to control. Make it work.
  • a dispensing operation is performed by the sample dispensing probes 104a and 104b according to the measurement items requested by the operation unit 117.
  • the sample dispensing probes 104a, 104b discharge the aspirated sample into the reaction vessel on the reaction disk 102, and the reagent dispensing probes 103a, 103b, to the reaction vessel. Reagents sucked from the reagent discs 101a and 101b by 103c and 103d are further added and stirred. After that, the light emitted from the light source 105 and passing through the reaction solution in the reaction vessel is detected by the multi-wavelength photometer 106, and the measurement result is transmitted to the control unit 119.
  • the control unit 119 obtains the concentration of a specific component in the sample by arithmetic processing from the transmitted measurement result.
  • the analysis result is notified to the user via the display unit 111, and is recorded in a recording unit (not shown) in the operation unit 117.
  • the automatic analyzer 100 is a device for measuring biochemical items
  • the measurement items are not limited to the biochemical items, and a measurement unit or the like for measuring immune items is adopted. be able to.
  • the number of reagent disks 101a and 101b arranged in one analysis unit is not limited to two, and may be three or more.
  • the sample transfer mechanism 110 is not indispensable, and the sample can be directly installed in the device by the user.
  • the automatic analyzer 100 is composed of one analysis unit
  • two or more analysis units can be provided.
  • the type of the analysis unit is not particularly limited, and one or more various analysis units such as a biochemical analysis unit, an immunoanalysis unit, and a blood coagulation analysis unit can be provided. Further, a unit for executing pretreatment and posttreatment on the sample can be separately provided.
  • control by the control unit 119 in the present invention is applied to the form in which a plurality of reagent disks are provided in one module, and a plurality of modules are provided in an apparatus having a plurality of modules including one reagent disk. It is different from the control between.
  • it is not hindered to further mount the reagent movement control among the plurality of modules, and the movement control within one module of the present invention and between the plurality of modules are not hindered. It is possible to simultaneously mount the movement control of the reagent in.
  • the plan execution unit 206 refers to the consumables information of the items necessary for performing the analysis registered in the analysis information holding unit 204 from the consumables information holding unit 205 (process S301). ).
  • the plan execution unit 206 determines whether or not the consumables information necessary for the analysis can be used. First, the plan execution unit 206 determines whether or not analysis is possible due to the movement of consumables (process S302).
  • the consumables information is, for example, the information shown in FIG. Of the information such as consumables No. 401, consumables name 402, consumables expiration date 403, consumables loading location 404, and consumables remaining amount 405 shown in FIG. 4, the consumables expiration date 403 and consumption are used for the analysis. Check if the remaining amount 405 is suitable.
  • the inter-disk movement permission setting may be set to enable / disable movement control by, for example, the operation unit 201 downloading parameters from an external medium or an external system. As shown in FIG. 5 and the like, the user may operate the input unit 118 to set whether or not the movement control is possible.
  • the inter-disk movement setting screen 900 shown in FIG. 5 is a screen displayed on the display unit 111, and is moved according to the selection area 901 for setting the movement control enable / disable itself, and the type of consumables or equipment maintenance parts.
  • a selection area 902 for setting control enable / disable is displayed, and the setting selected by the user is reflected in the device by pressing the registration button 903.
  • the consumables list screen 500 shown in FIG. 6 is a screen displayed on the display unit 111 as in FIG. 5, and it is possible to set whether or not to move each consumables list display area 501 of consumables or equipment maintenance parts. On the screen, enable / disable is set in conjunction with whether or not the consumables movement permission setting box 502 is checked.
  • the detergent and item names are displayed in the "name".
  • process S302 If it is determined in process S302 that analysis is possible due to the movement of consumables, the time required for consumables is calculated (process S303).
  • the consumables information holding unit 205 and the control information holding unit 209 and confirm whether the consumables that need to be moved are already scheduled to be used. If the consumables are not scheduled to be used or the consumables can be returned to the original reagent disc by the scheduled use, the time required for moving the consumables should be reduced to the original reagent discs if the consumables are scheduled to be used and the consumables should be returned to the original reagent disc by the scheduled use. If it cannot be returned, calculate the time required to move the consumables after the consumables are scheduled to be used.
  • the plan execution unit 206 determines whether or not the analysis can be performed by delaying the timing (. Process S304).
  • process S304 If it is determined in process S304 that analysis is possible by delaying the timing of dispensing, the waiting time until the start of analysis is calculated (process S305).
  • the plan execution unit 206 If it is determined that the analysis is not possible after the calculation or by delaying the dispensing timing in the process S304, the plan execution unit 206 then requests the analysis based on the process in the process S302 to the process S305. Determines whether or not is feasible (process S306).
  • process S306 If it is determined in process S306 that analysis is possible, an instruction is given to the analysis operation planning unit 207 to plan the analysis operation (process S312). After the implementation, this flow is terminated.
  • the plan execution unit 206 may determine that the analysis can be performed by allocating the consumables permitted by the inter-disc movement permission setting 406. If it is determined that the analysis is possible by delaying the dispensing timing, it is not determined that the analysis is impossible, and the process proceeds to the process S307.
  • the plan execution unit 206 compares the travel time calculated in the process S303 with the waiting time calculated in the process S305, and determines whether or not the travel time is shorter than the standby time (process S307). When it is determined that the movement time is shorter than the standby time, a movement plan for consumables is created and the process proceeds to the process S308 for execution. Further, when it is determined that the moving time is longer than the waiting time, an analysis plan for waiting for the delivery of consumables is created, and the process proceeds to the process S309 for execution.
  • the planning execution unit 206 determines that the time required to start the analysis is shorter. , Instruct the reagent movement operation planning unit 208 to create a movement plan of the reagent container necessary for performing the analysis (process S309). Following the movement plan, an instruction is given to the analysis operation planning unit 207 to carry out the analysis operation plan.
  • the planning execution unit 206 determines whether or not a moving operation for returning the consumables such as the reagent container moved by the processing of the processing S309 to the reagent disk of the moving source is necessary (processing S310).
  • the control information holding unit 209 is referred to, and it is determined whether or not the consumables that need to be moved are already scheduled to be used.
  • the user can also refer to the consumables information holding unit 205 to determine the number of consumables related to the reagent container, or determine the usage rate of the reagent on each disk for a certain period immediately before.
  • a method for determining by referring to the specified setting may be added, and the condition is not limited to one.
  • the planning execution unit 206 gives an instruction to the reagent moving operation planning unit 208, and the processing S309 After the analysis plan carried out in (Process S311), the reagent container movement plan is carried out. After the implementation, this flow is terminated.
  • the plan execution unit 206 issues an instruction to the analysis operation planning unit 207 after the designated time calculated in the process S305 to plan the analysis operation. (Processing S308). After the implementation, this flow is terminated. It is not necessary to stop the analysis during the specified time to be delayed, and it is possible to analyze items that are not related to the analysis.
  • the above-mentioned automatic analyzer 100 of the first embodiment of the present invention operates in parallel with a plurality of reagent disks 101a and 101b arranged in one module and analysis that can be stored in the reagent disks 101a and 101b.
  • the reagent container and equipment maintenance parts that had to be mounted on the plurality of reagent discs 101a and 101b can be mounted on only one of the reagent discs 101a and 101b, and the plurality of reagents can be dealt with.
  • the mounting efficiency of the disks 101a and 101b can be improved, and the operation load such as loading and unloading of the user can be reduced.
  • a disk-to-disk movement setting screen 900 for setting the possibility / non-movement control of consumables or equipment maintenance parts and a consumables list screen 500 are further provided, so that it is easy to control the movement control according to the operation of the device. It is possible to select the above, and it is possible to plan effective device operation and further reduce the load on the user.
  • disk-to-disk movement setting screen 900 and the consumables list screen 500 it is possible to set whether or not to move for each type of consumable or device maintenance component and for each item, so that the operation conditions of the device can be more detailed. It is possible to make settings according to the situation, and it is possible to further reduce the load.
  • control unit 119 calculates the movement time required for moving the consumables and the waiting time required for waiting to delay the dispensing timing, and when the moving time is shorter than the waiting time, the analysis executes the movement of the consumables.
  • control unit 119 determines whether or not the consumables return conditions are met, and if they are matched, the moved consumables are moved to the original reagent disks 101a and 101b for analysis. It is possible to control the movement of consumables in more detail according to the plan.
  • FIG. 7 is a diagram showing an example of an apparatus maintenance execution screen in the automated analyzer of the second embodiment
  • FIG. 8 is a diagram schematically showing a soft structure of a control unit
  • FIG. 9 is a procedure for creating an apparatus maintenance control plan including reagent movement. It is a flowchart which shows.
  • Example 1 was an embodiment relating to the sharing of consumables among a plurality of reagent disks 101a and 101b in the analysis operation, in the present embodiment, the consumables or equipment maintenance parts are shared. An aspect to be planned in maintenance will be described.
  • the consumables used in the above-mentioned device maintenance or the consumables used in the above-mentioned device maintenance are displayed on the device maintenance execution screen 600 using the consumables and the device maintenance parts mounted on the reagent disks 101a and 101b.
  • a list of equipment maintenance parts 601 is displayed. In this list 601 when the corresponding consumables or equipment maintenance parts are loaded on a plurality of reagent disks 101a and 101b, they are selected by means such as a drop box 602 that can be appropriately operated by the user.
  • the travel time required for the consumables selected in the drop box 602 is calculated, added to the time required for executing the device maintenance described above, and then the device maintenance execution screen is displayed.
  • the device maintenance execution time 603 is displayed on the 600, and the device maintenance selected by the user is executed by pressing the execute button 604. To close the execution screen 600, press the cancel button 605.
  • the consumable item in this embodiment is, for example, a detergent for special cleaning
  • the device maintenance component is, for example, a wiper for wiping off dirt and impurities in the reagent disks 101a and 101b.
  • FIG. 8 is a diagram schematically showing the soft structure of the control unit 119 of the automatic analyzer related to the above-mentioned equipment maintenance.
  • the control unit 700 of this embodiment has a receiving unit 702, a transmitting unit 703, an apparatus maintenance information holding unit 704, a consumables information holding unit 705, a planning execution unit 706, and an apparatus as software functions related to the control of the reagent transport mechanism 108. It includes a maintenance operation planning unit 707, a reagent movement operation planning unit 708, a control information holding unit 709, a control execution unit 710, and a mechanism control unit 711a, 711b, 711c.
  • the device maintenance information holding unit 704 holds the information necessary for performing the device maintenance set from the operation unit 701 via the receiving unit 702.
  • the information of the device maintenance information holding unit 704 includes the reagent information used for the device maintenance and is referred to by the planning execution unit 706.
  • the planning execution unit 706 refers to the information related to the equipment maintenance from the above-mentioned equipment maintenance information holding unit 704 and the above-mentioned consumables information holding unit 705, and executes the equipment maintenance operation planning unit 707 and the reagent transfer operation planning unit 708.
  • the execution results of the device maintenance operation planning unit 707 and the reagent movement operation planning unit 708 are held in the control information holding unit 709 as control information of each mechanism. The details of the planning logic used in the above planning execution will be described in detail later with reference to FIGS. 9 and later.
  • the other configurations / operations shown in FIGS. 2 and 8 are the same configurations / operations as the operation method of the automated analyzer and the automated analyzer of the first embodiment described above, and details thereof will be omitted. Further, the above-mentioned analysis information holding unit 204 and device maintenance information holding unit 704 described as separate software, and the analysis operation planning unit 207 and device maintenance operation planning unit 707 are responsible for the planning logic shown in FIGS. 3 to 9. If so, it can be realized as the same software.
  • the plan execution unit 706 refers from the consumables information holding unit 705 to the consumables information of the items necessary for performing the analysis registered in the device maintenance information holding unit 704 (the consumables information holding unit 705). Process S801).
  • the plan execution unit 706 confirms whether the consumables or equipment maintenance parts in the equipment are suitable for executing the equipment maintenance (process S802).
  • the process S803 is executed as the next step. If the device maintenance operation cannot be executed even if the device is moved, the process S804 is executed as the next step. Further, when the device maintenance operation can be executed by moving, the process S805 is executed as the next step.
  • the information appropriately set by the user on the above-mentioned device maintenance execution screen 600 and the above-mentioned consumables list screen 500 can be received from the operation unit 701 and added to the conditions.
  • the plan execution unit 706 issues an instruction to the device maintenance operation planning unit 707 to execute the device maintenance operation plan (process S803). After the implementation, this flow is terminated.
  • the plan execution unit 706 determines that the analysis cannot be continued, updates the device maintenance information holding unit 704, and updates the device maintenance information holding unit 704. Communication to the operation unit 701 via the transmission unit 703 is performed (process S804), and this flow ends.
  • the plan execution unit 706 creates a movement plan for consumables or equipment maintenance parts necessary for performing the equipment maintenance. Instruct the reagent transfer operation planning unit 708 (process S805). Following the creation of the movement plan, after the completion of the process S805, an instruction is given to the device maintenance operation planning unit 707 to implement the device maintenance operation plan (process S805).
  • the planning execution unit 706 instructs the reagent moving operation planning unit 708 to carry out a moving plan for returning the reagent container to be moved for the maintenance of the apparatus to the original reagent disks 101a and 101b after the processing S805. (Processing S806).
  • This process S806 is different from the processes S310 and S311 described in FIG. 3 of the first embodiment, and consumables or equipment maintenance parts are moved to the original reagent disks 101a and 101b without judgment, but the same as the process S310. It may be the one that makes a judgment. After the execution of the process S806, this flow is terminated.
  • the automatic analyzer of the second embodiment of the present invention also has almost the same effect as the above-mentioned automatic analyzer of the first embodiment.
  • control unit 119 confirms the equipment maintenance execution conditions, and when it is determined that maintenance can be executed by moving the consumables or the equipment maintenance parts, the control unit 119 executes the movement of the consumables or the equipment maintenance parts.
  • control unit 119 moves the consumables or the device maintenance parts to the reagent disks 101a and 101b again after executing the device maintenance plan with the movement, so that the movement control of the consumables can be finely controlled according to the analysis plan and the like. It will be possible.

Abstract

The present invention comprises: a plurality of reagent disks (101a, 101b) which are operated in parallel and arranged inside one module; a reagent transport mechanism (108) that transports, from a reagent loading/unloading area to the reagent disks (101a, 101b), a consumable or a device maintenance part which can be stored in the reagent disks (101a, 101b) and is required for analysis, and that moves the same between the plurality of reagent disks (101a, 101b); and a control unit (119) that controls a movement from a reagent disk (101a, 101b), which has the consumable or the device maintenance part, to a reagent disks (101a, 101b), which does not have the same and is a motion planning target. Accordingly, provided is an automatic analysis device including a reagent transport unit and a plurality of reagent storage units, wherein the operation load of a user can be reduced, and the mounting efficiency of the reagent storage unit can be improved.

Description

自動分析装置Automatic analyzer
　本発明は、血液等の成分を自動的に分析する自動分析装置に関する。 The present invention relates to an automatic analyzer that automatically analyzes components such as blood.
　供給ユニットや予備庫などの設備を設けずに、試薬容器をモジュール間で補充し合うことが可能な自動分析装置の一例として、特許文献１には、試薬容器が格納された試薬庫を備え、試薬容器から分注された試薬を試料と反応させることにより生成された反応液の成分を分析する複数のモジュールを有し、さらに、管理手段と、搬送手段とを有し、管理手段は、第１の抽出条件および第２の抽出条件を記憶する記憶部を有し、分析中または分析予定の所望モジュールの試薬庫から第１の抽出条件に該当する試薬容器が格納された試薬庫を搬送先として検索し、さらに、所望モジュール以外の試薬庫から第２の抽出条件に該当する試薬容器を搬送対象として検索する。搬送手段は、搬送先および搬送対象が検索されたことを受けて、搬送先に搬送対象を搬送する、ことが記載されている。 As an example of an automatic analyzer capable of replenishing reagent containers between modules without providing equipment such as a supply unit and a spare storage, Patent Document 1 includes a reagent storage in which the reagent containers are stored. It has a plurality of modules for analyzing the components of the reaction solution produced by reacting the reagent dispensed from the reagent container with the sample, and further has a control means and a transport means, and the control means is the first. It has a storage unit for storing the extraction condition 1 and the second extraction condition, and transports the reagent storage containing the reagent container corresponding to the first extraction condition from the reagent storage of the desired module being analyzed or to be analyzed. Further, a reagent container corresponding to the second extraction condition is searched from the reagent storage other than the desired module as a transport target. It is described that the transport means transports the transport target to the transport destination in response to the search for the transport destination and the transport target.
　測定を効率的に行える自動分析装置の一例として、特許文献２には、反応に使用する試薬を収納した試薬容器を載置する第１試薬ディスクと、第２試薬ディスクと、第１試薬ディスクと第２試薬ディスクとの間で、試薬容器を搬送する試薬搬送機構とを有し、コンピュータの判断部及び駆動制御部は、試薬搬送機構により、第２試薬ディスクに設置された試薬容器を第１試薬ディスクに搬送し、第１試薬ディスクに搬送された試薬容器に保持された試薬を用いて、キャリブレーションと精度管理測定の内少なくとも精度管理測定を実行した後、試薬搬送機構を用いて、試薬容器を第２試薬ディスクに戻すようにする、ことが記載されている。 As an example of an automatic analyzer capable of efficiently performing measurement, Patent Document 2 describes a first reagent disk, a second reagent disk, and a first reagent disk on which a reagent container containing a reagent used for a reaction is placed. It has a reagent transfer mechanism for transporting the reagent container between the second reagent disk, and the judgment unit and drive control unit of the computer first use the reagent transfer mechanism to transfer the reagent container installed on the second reagent disk. After performing at least quality control measurement among calibration and quality control measurement using the reagent transferred to the reagent disk and held in the reagent container transferred to the first reagent disk, the reagent is transferred using the reagent transfer mechanism. It is stated that the container should be returned to the second reagent disc.
特開２０１５－１１４１２２号公報Japanese Unexamined Patent Publication No. 2015-114122 特開２０１３－２１７７４１号公報Japanese Unexamined Patent Publication No. 2013-21741
　自動分析装置は、血液や尿などの検体を検体容器から反応容器へ分注し、更に試薬容器から上記反応容器へ試薬を分注し、検体と試薬の混合液を光度計の如き測定手段によって測定して定性あるいは定量分析を行う装置である。 The automatic analyzer dispenses a sample such as blood or urine from the sample container to the reaction vessel, further dispenses the reagent from the reagent container to the reaction vessel, and measures a mixed solution of the sample and the reagent by a measuring means such as a photometric meter. It is a device that measures and performs qualitative or quantitative analysis.
　自動分析装置で使用される試薬容器は、あらかじめ装置内の試薬保管部に設置された上で、残量や使用期限などを含む情報を管理されている。そして、ユーザによる試薬交換作業低減のため、試薬容器を自動で装置内の試薬保管容器へ設置する機能を有する装置が近年、上市されている。 The reagent container used in the automated analyzer is installed in the reagent storage section inside the device in advance, and information including the remaining amount and expiration date is managed. In recent years, an apparatus having a function of automatically installing a reagent container in a reagent storage container in the apparatus has been put on the market in order to reduce the reagent exchange work by the user.
　また、上述の特許文献１には、試薬を所望しているモジュールの試薬保管部に対して別のモジュールの試薬保管部から試薬搬送部を用いて試薬容器を搬送するものが開示されている。 Further, Patent Document 1 described above discloses that a reagent container is transported from a reagent storage section of another module to a reagent storage section of a module in which a reagent is desired, using a reagent transport section.
　また、特許文献２には、第１の試薬保管部に格納された試薬を、上述の試薬搬送部を用いて第２の試薬保管部に搬送し、キャリブレーションないし精度管理測定を実行した後に、上述の試薬搬送部を用いて第１の試薬保管部に戻す技術が開示されている。 Further, in Patent Document 2, the reagent stored in the first reagent storage unit is transported to the second reagent storage unit using the above-mentioned reagent transport unit, and after calibration or quality control measurement is performed, the reagent is transferred to the second reagent storage unit. A technique for returning to the first reagent storage unit using the above-mentioned reagent transport unit is disclosed.
　近年は、１台の自動分析装置を昼夜使用することが多くなっている。しかし、夜間勤務にて装置を使用するユーザは、必ずしもその自動分析装置の担当者とは限らない。このため、試薬交換作業や、その他の装置メンテナンスなどはすべて日勤担当者が請け負うのが一般的である。また、２４時間の運用では、メンテナンスに時間がかかると、その分だけ後ろの検査に遅れが生じる可能性があるため、試薬交換などの時間を要するメンテナンスの必要をなるべく減らすことが求められている。 In recent years, one automatic analyzer is often used day and night. However, the user who uses the device at night shift is not necessarily the person in charge of the automatic analyzer. For this reason, it is common for day shift personnel to undertake all reagent replacement work and other equipment maintenance. In addition, in 24-hour operation, if maintenance takes time, there is a possibility that the subsequent inspection will be delayed by that amount, so it is required to reduce the need for time-consuming maintenance such as reagent replacement as much as possible. ..
　また、分析動作や装置メンテナンス動作中に使用される洗剤等の消耗品も、試薬と同様に装置内の試薬保管部に保管されることがある。しかしながら、試薬保管部にアクセスできる機構はそのハード制約上制限させることが多く、１つのモジュール内に複数の試薬保管部を持つ自動分析装置では、同一の試薬ないし洗剤等の消耗品であったとしても、すべての消耗品にアクセスする機構で使用するためにはすべての試薬保管部に設置する必要があった。 In addition, consumables such as detergents used during analysis operation and equipment maintenance operation may also be stored in the reagent storage section inside the equipment in the same way as reagents. However, the mechanism that can access the reagent storage unit is often limited due to its hardware restrictions, and in an automated analyzer having multiple reagent storage units in one module, it is assumed that the same reagent or detergent is a consumable item. However, it had to be installed in all reagent storages in order to be used in a mechanism to access all consumables.
　特許文献１に記載の技術では、複数の抽出条件によって、例えばモジュールが休止状態である場合で試薬残量が規定値を下回った場合に、試薬保管部から別モジュールの試薬保管部に対して試薬容器の搬送を行うことが記載されている。 In the technique described in Patent Document 1, when the remaining amount of reagent falls below a specified value, for example, when the module is in a dormant state due to a plurality of extraction conditions, the reagent is transferred from the reagent storage unit to the reagent storage unit of another module. It is described that the container is transported.
　しかしながら、運用中の自動分析装置内の機構は駆動しているため、運用中のシステムにおいては、抽出条件のみで稼働中のモジュールの試薬保管部から別の稼働中のモジュールの試薬保管部に対して機構の干渉を防ぎつつ試薬搬送を行うことは抽出条件が複雑となってしまい、現実には実施困難である。 However, since the mechanism inside the automatic analyzer in operation is driven, in the system in operation, from the reagent storage part of the module that is operating only under the extraction conditions to the reagent storage part of another module that is in operation. Therefore, it is difficult to carry out reagent transfer while preventing mechanical interference because the extraction conditions become complicated.
　また、特許文献２に記載の技術では、複数の試薬保管部を備えた自動分析装置において、片方の試薬保管部に設置されて使用される試薬について使用準備を完了させた状態で、もう片方の試薬保管部に保管しておくことが記載されている。 Further, in the technique described in Patent Document 2, in an automatic analyzer provided with a plurality of reagent storage units, the reagent installed in one reagent storage unit and used is ready for use in the other state. It is described that it should be stored in the reagent storage unit.
　しかしながら、特許文献２に記載の技術においても、不足した消耗品の補充に留まっており、運用中のシステムにおいて試薬保管部は反応容器へ試薬を分注する等の分析のための駆動を行っているおそれがある。このため、分析を止めることなく複数の試薬保管部から試薬搬送部を用いて試薬容器の共有を成すためには、より効率的な制御ロジックが必要である。 However, even in the technique described in Patent Document 2, the shortage of consumables is only replenished, and in the operating system, the reagent storage unit drives for analysis such as dispensing the reagent into the reaction vessel. There is a risk of being. Therefore, in order to share the reagent container from a plurality of reagent storage units using the reagent transport unit without stopping the analysis, a more efficient control logic is required.
　本発明は上記に鑑みてなされたものであり、試薬搬送部と複数の試薬保管部とを備えている自動分析装置において、ユーザの操作負荷を軽減することができるとともに、試薬保管部の搭載効率を向上することができる自動分析装置を提供する。 The present invention has been made in view of the above, and in an automatic analyzer provided with a reagent transport unit and a plurality of reagent storage units, it is possible to reduce the operation load of the user and to mount the reagent storage unit efficiently. Provide an automatic analyzer that can improve.
　本発明は、上記課題を解決する手段を複数含んでいるが、その一例を挙げるならば、それぞれが並列して動作する、１つのモジュール内に複数配置された試薬ディスクと、前記試薬ディスク内に保管可能な分析に必要な消耗品あるいは装置メンテナンス部品を装置内への設置位置から前記試薬ディスクへ搬送させるとともに、複数の前記試薬ディスクの間で移動させる搬送部と、前記消耗品あるいは前記装置メンテナンス部品を、前記消耗品あるいは前記装置メンテナンス部品を有している前記試薬ディスクから、前記消耗品あるいは前記装置メンテナンス部品を有していない動作計画対象の試薬ディスクへ移動させる移動制御を実行する制御部と、を備えたことを特徴とする。 The present invention includes a plurality of means for solving the above problems, and to give an example thereof, a plurality of reagent disks arranged in one module, each of which operates in parallel, and the reagent disk. Consumables or equipment maintenance parts required for storable analysis are transported from the installation position in the equipment to the reagent discs, and the transport unit is moved between the plurality of reagent discs, and the consumables or the equipment maintenance. A control unit that executes movement control to move a component from the reagent disk having the consumable item or the device maintenance component to a reagent disk subject to operation planning that does not have the consumable item or the device maintenance component. It is characterized by having.
　本発明によれば、ユーザの操作負荷を軽減することができるとともに、試薬保管部の搭載効率を向上することができる。上記した以外の課題、構成および効果は、以下の実施例の説明により明らかにされる。 According to the present invention, it is possible to reduce the operation load of the user and improve the mounting efficiency of the reagent storage unit. Issues, configurations and effects other than those mentioned above will be clarified by the description of the following examples.
本発明の実施例１の自動分析装置の全体構成を概略的に示す図である。It is a figure which shows schematic the whole structure of the automatic analyzer of Example 1 of this invention. 実施例１の自動分析装置における制御部のソフト構造を概略的に示す図である。It is a figure which shows schematic the soft structure of the control part in the automatic analyzer of Example 1. FIG. 実施例１の自動分析装置における試薬移動を並列させた制御計画の作成手順を示すフローチャートである。It is a flowchart which shows the creation procedure of the control plan which paralleled the reagent movement in the automatic analyzer of Example 1. FIG. 実施例１の自動分析装置における消耗品管理情報の一例を示す図である。It is a figure which shows an example of the consumables management information in the automatic analyzer of Example 1. FIG. 実施例１の自動分析装置における消耗品管理画面の一例を示す図である。It is a figure which shows an example of the consumables management screen in the automatic analyzer of Example 1. FIG. 実施例１の自動分析装置における消耗品管理画面の他の一例を示す図である。It is a figure which shows another example of the consumables management screen in the automatic analyzer of Example 1. FIG. 本発明の実施例２の自動分析装置における装置メンテナンス実行画面例を示す図である。It is a figure which shows the device maintenance execution screen example in the automatic analyzer of Example 2 of this invention. 実施例２の自動分析装置における制御部のソフト構造を概略的に示す図である。It is a figure which shows schematic the soft structure of the control part in the automatic analyzer of Example 2. FIG. 実施例２の自動分析装置における試薬移動を含む装置メンテナンス制御計画の作成手順を示すフローチャートである。It is a flowchart which shows the creation procedure of the apparatus maintenance control plan which includes the reagent movement in the automatic analyzer of Example 2. FIG.
　以下に本発明の自動分析装置の実施例を、図面を用いて説明する。なお、本明細書で用いる図面において、同一のまたは対応する構成要素には同一、または類似の符号を付け、これらの構成要素については繰り返しの説明を省略する場合がある。 An embodiment of the automatic analyzer of the present invention will be described below with reference to the drawings. In the drawings used in the present specification, the same or corresponding components may be designated by the same or similar reference numerals, and repeated description of these components may be omitted.
　＜実施例１＞　
　本発明の自動分析装置の実施例１について図１乃至図６を用いて説明する。図１は本実施例１の自動分析装置の全体構成を概略的に示す図、図２は制御部のソフト構造を概略的に示す図、図３は試薬移動を並列させた制御計画の作成手順を示すフローチャート、図４は消耗品管理情報の一例を示す図、図５は消耗品管理画面の一例を示す図、図６は消耗品管理画面の他の一例を示す図である。 <Example 1>
The first embodiment of the automatic analyzer of the present invention will be described with reference to FIGS. 1 to 6. FIG. 1 is a diagram schematically showing the overall configuration of the automated analyzer of the first embodiment, FIG. 2 is a diagram schematically showing the soft structure of the control unit, and FIG. 3 is a procedure for creating a control plan in which reagent movements are arranged in parallel. FIG. 4 is a diagram showing an example of consumables management information, FIG. 5 is a diagram showing an example of a consumables management screen, and FIG. 6 is a diagram showing another example of the consumables management screen.
　最初に、自動分析装置の全体構成について図１を用いて説明する。図１に示す自動分析装置１００は、複数の試薬ディスク１０１ａ，１０１ｂ、複数の試薬分注プローブ１０３ａ，１０３ｂ，１０３ｃ，１０３ｄ、反応ディスク１０２、検体分注プローブ１０４ａ，１０４ｂ、測定部（光源１０５、多波長光度計１０６）、試薬搬入出エリア１０９、試薬搬送機構１０８、検体搬送機構１１０、制御部１１９、表示部１１１、操作部１１７、入力部１１８などにより主に構成されている。 First, the overall configuration of the automated analyzer will be described with reference to FIG. The automatic analyzer 100 shown in FIG. 1 includes a plurality of reagent disks 101a, 101b, a plurality of reagent dispensing probes 103a, 103b, 103c, 103d, a reaction disk 102, a sample dispensing probe 104a, 104b, and a measuring unit (light source 105, It is mainly composed of a multi-wavelength photometer 106), a reagent loading / unloading area 109, a reagent transporting mechanism 108, a sample transporting mechanism 110, a control unit 119, a display unit 111, an operation unit 117, an input unit 118, and the like.
　反応ディスク１０２は、試料と試薬を反応させる反応容器１１５を円状に複数個備えており、反応ディスク１０２が回転動作を行うことで、反応容器１１５を円周上の所定の位置へ移動させる。 The reaction disk 102 includes a plurality of reaction containers 115 for reacting a sample and a reagent in a circular shape, and the reaction disk 102 rotates to move the reaction container 115 to a predetermined position on the circumference.
　検体分注プローブ１０４ａ，１０４ｂは回転および上下動作が可能であり、検体搬入機構（図示省略）から自動分析装置内に搬入され、検体搬送機構１１０によって搬送された検体容器１１２から、所定量の検体を吸引し反応ディスク１０２に試料として吐出する。 The sample dispensing probes 104a and 104b can rotate and move up and down, and are carried into the automatic analyzer from the sample carrying mechanism (not shown), and a predetermined amount of sample is taken from the sample container 112 carried by the sample carrying mechanism 110. Is sucked and discharged as a sample to the reaction disk 102.
　また、試薬ディスク１０１ａ，１０１ｂは、複数個の試薬容器１１３ａ，１１３ｂを円状に保持することが可能であり、複数の試薬容器１１３ａ，１１３ｂを一定温度に保冷して保存する保冷庫としての役割も有している。試薬ディスク１０１ａ，１０１ｂが回転動作を行うことで試薬容器１１３ａ，１１３ｂを円周上の所定の位置へ移動させる。試薬容器１１３ａ，１１３ｂには、分析に用いる試薬や自動分析装置１００内の各機構の洗浄に使用する洗剤が封入されている。 Further, the reagent disks 101a and 101b can hold a plurality of reagent containers 113a and 113b in a circular shape, and serve as a cold storage for storing the plurality of reagent containers 113a and 113b at a constant temperature. Also has. The reagent discs 101a and 101b rotate to move the reagent containers 113a and 113b to predetermined positions on the circumference. Reagent containers 113a and 113b contain reagents used for analysis and detergents used for cleaning each mechanism in the automatic analyzer 100.
　本実施例では、試薬ディスク１０１ａ，１０１ｂは、１つのモジュール内に２つ配置されており、それぞれが並列して動作する。また、試薬ディスク１０１ａ，１０１ｂは、それぞれ、試薬容器１１３ａ，１１３ｂを搬送および移動可能な試薬搬送機構１０８を介して試薬搬入出エリア１０９に接続されており、相互に搬入出が可能である。 In this embodiment, two reagent disks 101a and 101b are arranged in one module, and each of them operates in parallel. Further, the reagent disks 101a and 101b are connected to the reagent loading / unloading area 109 via the reagent transporting mechanism 108 which can transport and move the reagent containers 113a and 113b, respectively, and can be loaded / unloaded from each other.
　試薬搬送機構１０８は、試薬ディスク１０１ａ，１０１ｂ内に保管可能な分析に必要な消耗品あるいは装置メンテナンス部品、本実施例では、分析に用いる試薬が収容された試薬容器１１３ａ，１１３ｂ、あるいは分析後に使用する洗浄液が収容された洗浄容器を試薬搬入出エリア１０９から試薬ディスク１０１ａ，１０１ｂへ搬送させるとともに、複数の試薬ディスク１０１ａ，１０１ｂの間で移動させる。 The reagent transfer mechanism 108 is a consumable or equipment maintenance component that can be stored in the reagent disks 101a and 101b and is necessary for analysis. In this embodiment, the reagent containers 113a and 113b containing the reagents used for analysis are used, or after analysis. The cleaning container containing the cleaning liquid to be used is transported from the reagent loading / unloading area 109 to the reagent discs 101a and 101b, and is also moved between the plurality of reagent discs 101a and 101b.
　なお、本発明では、試薬ディスク１０１ａ，１０１ｂの間での試薬容器１１３ａ，１１３ｂ等のやり取りは「移動」と、試薬容器設置エリア１１４から各試薬ディスク１０１ａ，１０１ｂへの試薬容器１１３ａ，１１３ｂ等のやり取りは「搬送」と定義する。 In the present invention, the exchange of the reagent containers 113a, 113b and the like between the reagent discs 101a and 101b is "movement", and the reagent containers 113a, 113b and the like from the reagent container installation area 114 to the reagent discs 101a and 101b are used. Communication is defined as "transportation".
　試薬ディスク１０１ａと反応ディスク１０２の間には、試薬分注プローブ１０３ａ，１０３ｂが、試薬ディスク１０１ｂと反応ディスク１０２の間には、試薬分注プローブ１０３ｃ，１０３ｄが備えられており、それぞれが接続する試薬ディスク１０１ａ，１０１ｂ内の試薬容器１１３ａ，１１３ｂから所定量の試薬を分注し、反応容器１１５へ吐出する。 Reagent dispensing probes 103a and 103b are provided between the reagent disk 101a and the reaction disk 102, and reagent dispensing probes 103c and 103d are provided between the reagent disk 101b and the reaction disk 102, and they are connected to each other. A predetermined amount of reagent is dispensed from the reagent containers 113a and 113b in the reagent disks 101a and 101b, and discharged to the reaction container 115.
　反応ディスク１０２の周囲には、更に、光源１０５、多波長光度計１０６、反応容器洗浄機構１０７が備えられており、反応容器内の試料と試薬の混合物の吸光度測定、および洗浄を実施する。 A light source 105, a multi-wavelength photometer 106, and a reaction vessel cleaning mechanism 107 are further provided around the reaction disk 102 to measure the absorbance of the mixture of the sample and the reagent in the reaction vessel and perform cleaning.
　上述の検体分注プローブ１０４ａ，１０４ｂによる分注動作以降、その後の分析に必要な動作は寸断なく実施される。そのため、複数の検体分注プローブ１０４ａ，１０４ｂのどちらで分注を行ったか、すなわち反応ディスク１０２上のどの反応容器１１５に試料が添加されたかによって、その後の分析動作のある時点で使用できる試薬容器１１３ａ，１１３ｂが限られる。具体的には、その時点で対応する試薬分注プローブ１０３ａ，１０３ｂ，１０３ｃ，１０３ｄのいずれかがアクセス可能な試薬ディスク１０１ａ，１０１ｂ上に積載されているものに限られる。 After the dispensing operation by the sample dispensing probes 104a and 104b described above, the operation necessary for the subsequent analysis is carried out without interruption. Therefore, depending on which of the plurality of sample dispensing probes 104a and 104b was used for dispensing, that is, which reaction container 115 on the reaction disk 102 the sample was added to, the reagent container that can be used at a certain point in the subsequent analysis operation. 113a and 113b are limited. Specifically, it is limited to those in which any of the corresponding reagent dispensing probes 103a, 103b, 103c, 103d at that time is loaded on the accessible reagent disks 101a, 101b.
　制御部１１９は、ＣＰＵやメモリを備えたコンピュータにより構成される操作部１１７より、検体容器１１２内に紐づく検体情報と、入力部１１８によって入力された依頼情報を受信し、機構の動作計画を作成し機構を制御する。 The control unit 119 receives the sample information associated with the sample container 112 and the request information input by the input unit 118 from the operation unit 117 composed of a computer equipped with a CPU and a memory, and determines the operation plan of the mechanism. Create and control the mechanism.
　更に、制御部１１９は、測定部から取得した測定結果を操作部１１７に送信する。操作部は、受信した測定結果から演算処理を行い、検体内の指定成分の濃度を算出し、表示部１１１に表示する。 Further, the control unit 119 transmits the measurement result acquired from the measurement unit to the operation unit 117. The operation unit performs arithmetic processing from the received measurement result, calculates the concentration of the designated component in the sample, and displays it on the display unit 111.
　また、制御部１１９は、本実施例では、消耗品あるいは装置メンテナンス部品を、消耗品あるいは装置メンテナンス部品を有している試薬ディスク１０１ａ，１０１ｂから、消耗品あるいは装置メンテナンス部品を有していない動作計画対象の試薬ディスク１０１ａ，１０１ｂへ移動させる移動制御を実行する。この制御により、消耗品あるいは装置メンテナンス部品を複数の試薬ディスク１０１ａ，１０１ｂの間で補いあうものとする。その詳細は後述する。 Further, in this embodiment, the control unit 119 operates without consumables or equipment maintenance parts from the reagent disks 101a and 101b having consumables or equipment maintenance parts. The movement control for moving to the reagent disks 101a and 101b to be planned is executed. By this control, consumables or equipment maintenance parts are complemented among the plurality of reagent disks 101a and 101b. The details will be described later.
　操作部１１７や制御部１１９は、自動分析装置１００内の各機構に有線或いは無線のネットワーク回線１１６ａ，１１６ｂによって接続されている。 The operation unit 117 and the control unit 119 are connected to each mechanism in the automatic analyzer 100 by wired or wireless network lines 116a and 116b.
　これら操作部１１７や制御部１１９は、汎用のコンピュータを用いて実現されてもよく、コンピュータ上で実行されるプログラムの機能として実現されてもよい。それらが担の処理は、プログラムコードとしてメモリなどの記録部に格納し、ＣＰＵ（Ｃｅｎｔｒａｌ　Ｐｒｏｃｅｓｓｉｎｇ　Ｕｎｉｔ）などのプロセッサが各プログラムコードを実行することによって実現されてもよい。なお、専用の回路基板などのハードウェアによって構成されていてもよい。 These operation units 117 and control units 119 may be realized by using a general-purpose computer, or may be realized as a function of a program executed on the computer. The processing carried by them may be stored as a program code in a recording unit such as a memory, and may be realized by executing each program code by a processor such as a CPU (Central Processing Unit). It may be configured by hardware such as a dedicated circuit board.
　表示部１１１は、測定する検体に対して測定する測定項目をオーダーする操作画面、測定した結果を確認する画面、等の様々な画面が表示される部分であり、液晶ディスプレイ等で構成される。なお、液晶ディスプレイである必要はなく、プリンタなどに置き換えてもよいし、ディスプレイとプリンタ等とで構成することが、更には後述の入力部１１８を兼ねたタッチパネルタイプのディスプレイとすることができる。 The display unit 111 is a part on which various screens such as an operation screen for ordering measurement items to be measured for a sample to be measured, a screen for confirming the measurement result, and the like are displayed, and is composed of a liquid crystal display or the like. It does not have to be a liquid crystal display, and may be replaced with a printer or the like, and a display and a printer or the like can be configured to form a touch panel type display that also serves as an input unit 118, which will be described later.
　入力部１１８は、表示部１１１に表示された操作画面に基づいて各種パラメータや設定、測定結果、測定の依頼情報、分析開始や停止の指示等を入力するための部分であり、キーボードやマウスなどで構成される。 The input unit 118 is a part for inputting various parameters and settings, measurement results, measurement request information, analysis start / stop instructions, etc. based on the operation screen displayed on the display unit 111, such as a keyboard and a mouse. Consists of.
　次に、本実施例の自動分析装置１００における、試薬容器１１３ａ，１１３ｂの共有ロジックと、試薬搬送機構１０８の制御計画方法について図２および図３を用いて説明する。 Next, the shared logic of the reagent containers 113a and 113b and the control planning method of the reagent transfer mechanism 108 in the automatic analyzer 100 of this embodiment will be described with reference to FIGS. 2 and 3.
　図２は、図１に示す自動分析装置の制御部１１９のソフト構造を概略的に示す図であり、図２の制御部２００は図１の制御部１１９内の一部となる。 FIG. 2 is a diagram schematically showing the soft structure of the control unit 119 of the automatic analyzer shown in FIG. 1, and the control unit 200 of FIG. 2 is a part of the control unit 119 of FIG.
　本実施例の制御部２００は、試薬搬送機構１０８の制御に関連するソフトウェア機能として、受信部２０２、送信部２０３、分析情報保持部２０４、消耗品情報保持部２０５、計画実行部２０６、分析動作計画部２０７、試薬移動動作計画部２０８、制御情報保持部２０９、制御実行部２１０、機構制御部２１１ａ，２１１ｂ，２１１ｃを備えている。 The control unit 200 of this embodiment has a receiving unit 202, a transmitting unit 203, an analysis information holding unit 204, a consumables information holding unit 205, a planning execution unit 206, and an analysis operation as software functions related to the control of the reagent transport mechanism 108. It includes a planning unit 207, a reagent moving operation planning unit 208, a control information holding unit 209, a control execution unit 210, and a mechanism control unit 211a, 211b, 211c.
　分析情報保持部２０４は、受信部２０２を介して操作部２０１から入力、設定された分析動作を行うために必要な情報を保持する。本実施例では、分析情報保持部２０４の情報は、分析に使用する消耗品情報を含み、計画実行部２０６により参照される。 The analysis information holding unit 204 holds information necessary for performing the analysis operation input and set from the operation unit 201 via the receiving unit 202. In this embodiment, the information in the analysis information holding unit 204 includes the consumables information used for the analysis and is referred to by the planning execution unit 206.
　消耗品情報保持部２０５は、分析動作に使用可能な消耗品情報の一覧、および試薬ディスク１０１ａ，１０１ｂの移動可否情報を保持する。本実施例では、各情報は受信部２０２乃至制御実行部２１０によって編集され、送信部２０３を介して操作部２０１に送信される。また、消耗品情報保持部２０５の情報は、計画実行部２０６により参照される。 The consumables information holding unit 205 holds a list of consumables information that can be used for the analysis operation, and information on whether or not the reagent disks 101a and 101b can be moved. In this embodiment, each information is edited by the receiving unit 202 to the control executing unit 210, and is transmitted to the operating unit 201 via the transmitting unit 203. Further, the information of the consumables information holding unit 205 is referred to by the planning execution unit 206.
　計画実行部２０６は、分析動作計画部２０７および試薬移動動作計画部２０８を有しており、上述の分析情報保持部２０４および上述の消耗品情報保持部２０５の分析に係る情報を参照し、分析動作計画部２０７により分析動作を計画するとともに、試薬移動動作計画部２０８により試薬移動動作を計画する。分析動作計画部２０７および試薬移動動作計画部２０８の実行結果は、各機構の制御情報として制御情報保持部２０９に保持される。上記計画実行で用いられる計画ロジックの詳細は図３以降を用いて後ほど詳しく説明する。 The planning execution unit 206 has an analysis operation planning unit 207 and a reagent transfer operation planning unit 208, and refers to and analyzes information related to the analysis of the above-mentioned analysis information holding unit 204 and the above-mentioned consumables information holding unit 205. The operation planning unit 207 plans the analysis operation, and the reagent transfer operation planning unit 208 plans the reagent transfer operation. The execution results of the analysis operation planning unit 207 and the reagent movement operation planning unit 208 are held in the control information holding unit 209 as control information of each mechanism. The details of the planning logic used in the above planning execution will be described in detail later with reference to FIGS. 3 and later.
　制御実行部２１０は、制御情報保持部２０９に保持された制御情報を基に、試薬搬送機構制御部２１１ａや、試薬ディスク制御部２１１ｂ、試薬プローブ制御部２１１ｃに対して制御指示を出力する。試薬搬送機構制御部２１１ａは試薬搬送機構１０８を、試薬ディスク制御部２１１ｂは試薬ディスク１０１ａ，１０１ｂを、試薬プローブ制御部２１１ｃは試薬分注プローブ１０３ａ，１０３ｂ，１０３ｃ，１０３ｄを、それぞれ制御指示通りに動作させる。 The control execution unit 210 outputs control instructions to the reagent transfer mechanism control unit 211a, the reagent disk control unit 211b, and the reagent probe control unit 211c based on the control information held in the control information holding unit 209. The reagent transfer mechanism control unit 211a has the reagent transfer mechanism 108, the reagent disk control unit 211b has the reagent disks 101a and 101b, and the reagent probe control unit 211c has the reagent dispensing probes 103a, 103b, 103c and 103d, respectively, as instructed to control. Make it work.
　次に、図１に示す自動分析装置１００の機構動作の概略を説明する。 Next, the outline of the mechanism operation of the automatic analyzer 100 shown in FIG. 1 will be described.
　検体搬送機構１１０により搬送された検体容器１１２に保持された各検体に対して、操作部１１７により依頼された測定項目に従い、検体分注プローブ１０４ａ，１０４ｂにより分注動作が実施される。 For each sample held in the sample container 112 transported by the sample transfer mechanism 110, a dispensing operation is performed by the sample dispensing probes 104a and 104b according to the measurement items requested by the operation unit 117.
　測定項目が生化学項目の場合には、検体分注プローブ１０４ａ，１０４ｂは、吸引した検体を反応ディスク１０２上にある反応容器に吐出し、その反応容器に対して試薬分注プローブ１０３ａ，１０３ｂ，１０３ｃ，１０３ｄにより試薬ディスク１０１ａ，１０１ｂ上から吸引した試薬をさらに添加し、攪拌する。その後、光源１０５から放出され、反応容器内の反応液を通過した光を多波長光度計１０６により検出し、測定結果が制御部１１９に送信される。 When the measurement item is a biochemical item, the sample dispensing probes 104a, 104b discharge the aspirated sample into the reaction vessel on the reaction disk 102, and the reagent dispensing probes 103a, 103b, to the reaction vessel. Reagents sucked from the reagent discs 101a and 101b by 103c and 103d are further added and stirred. After that, the light emitted from the light source 105 and passing through the reaction solution in the reaction vessel is detected by the multi-wavelength photometer 106, and the measurement result is transmitted to the control unit 119.
　制御部１１９は、送信された測定結果から演算処理によって検体内の特定成分の濃度を求める。分析結果は表示部１１１を介してユーザに通知されるとともに、操作部１１７内の記録部（図示省略）に記録される。 The control unit 119 obtains the concentration of a specific component in the sample by arithmetic processing from the transmitted measurement result. The analysis result is notified to the user via the display unit 111, and is recorded in a recording unit (not shown) in the operation unit 117.
　なお、本実施例では、自動分析装置１００が生化学項目を測定する装置である場合について説明したが、測定項目は生化学項目のみに限定されず、免疫項目を測定する測定部等を採用することができる。 In this embodiment, the case where the automatic analyzer 100 is a device for measuring biochemical items has been described, but the measurement items are not limited to the biochemical items, and a measurement unit or the like for measuring immune items is adopted. be able to.
　また、１つの分析ユニット内に配置される試薬ディスク１０１ａ，１０１ｂの数は２つに限定されず、３つ以上であってもよい。 Further, the number of reagent disks 101a and 101b arranged in one analysis unit is not limited to two, and may be three or more.
　更に、自動分析装置１００が検体搬送機構１１０を備える場合について説明したが、検体搬送機構１１０は必須ではなく、検体を装置内にユーザが直接設置する形態とすることができる。 Further, although the case where the automatic analyzer 100 includes the sample transfer mechanism 110 has been described, the sample transfer mechanism 110 is not indispensable, and the sample can be directly installed in the device by the user.
　また、自動分析装置１００が１つの分析ユニットで構成される場合について説明しているが、分析ユニットは２つ以上備えることができる。この場合、分析ユニットの種類も特に限定されず、生化学分析ユニットや免疫分析ユニット、血液凝固分析ユニット等の各種分析ユニットをそれぞれ１つ以上備えることができる。また、検体に対して前処理や後処理を実行するユニットを別途設けることができる。 Further, although the case where the automatic analyzer 100 is composed of one analysis unit is described, two or more analysis units can be provided. In this case, the type of the analysis unit is not particularly limited, and one or more various analysis units such as a biochemical analysis unit, an immunoanalysis unit, and a blood coagulation analysis unit can be provided. Further, a unit for executing pretreatment and posttreatment on the sample can be separately provided.
　ただし、本発明における制御部１１９での制御は、１モジュール内に複数の試薬ディスクを備えている形態に適用されるものであって、１つの試薬ディスクを備えたモジュールを複数有する装置において複数モジュール間における制御とは別物である。ただし、１つの試薬ディスクを備えたモジュールを複数有する場合に、複数モジュール間における試薬の移動制御を更に搭載することが妨げられるものではなく、本発明の１モジュール内での移動制御と複数モジュール間における試薬の移動制御とを同時に搭載することができる。 However, the control by the control unit 119 in the present invention is applied to the form in which a plurality of reagent disks are provided in one module, and a plurality of modules are provided in an apparatus having a plurality of modules including one reagent disk. It is different from the control between. However, when there are a plurality of modules provided with one reagent disk, it is not hindered to further mount the reagent movement control among the plurality of modules, and the movement control within one module of the present invention and between the plurality of modules are not hindered. It is possible to simultaneously mount the movement control of the reagent in.
　次いで、制御部２００における計画実行部２０６の計画ロジックの詳細について図３乃至図６を用いて説明する。 Next, the details of the planning logic of the planning execution unit 206 in the control unit 200 will be described with reference to FIGS. 3 to 6.
　図３に示すように、最初に、計画実行部２０６は、消耗品情報保持部２０５より分析情報保持部２０４に登録された分析を行うための必要な項目の消耗品情報を参照する（処理Ｓ３０１）。 As shown in FIG. 3, first, the plan execution unit 206 refers to the consumables information of the items necessary for performing the analysis registered in the analysis information holding unit 204 from the consumables information holding unit 205 (process S301). ).
　処理Ｓ３０１で参照した情報を元に、計画実行部２０６は、当該分析に必要な消耗品情報が使用可能か否かを判断する。最初に、計画実行部２０６は、消耗品の移動によって分析可能となるか否かを判断する（処理Ｓ３０２）。消耗品情報は、例えば図４に示す情報である。図4に示す消耗品Ｎｏ４０１、消耗品名称４０２、消耗品使用期限４０３、消耗品積載場所４０４、消耗品残量４０５等の各情報のうち、当該分析を行うために消耗品使用期限４０３や消耗品残量４０５が適しているかを確認する。 Based on the information referred to in the process S301, the plan execution unit 206 determines whether or not the consumables information necessary for the analysis can be used. First, the plan execution unit 206 determines whether or not analysis is possible due to the movement of consumables (process S302). The consumables information is, for example, the information shown in FIG. Of the information such as consumables No. 401, consumables name 402, consumables expiration date 403, consumables loading location 404, and consumables remaining amount 405 shown in FIG. 4, the consumables expiration date 403 and consumption are used for the analysis. Check if the remaining amount 405 is suitable.
　図４に示す消耗品情報のうち、ディスク間移動許可設定は、例えば、外部メディアもしくは外部システムから操作部２０１がパラメータダウンロードを行うことで移動制御の可／不可の設定する形態としてもよいし、図５等に示すようにユーザが入力部１１８を操作して移動制御の可／不可の設定を行う形態としてもよい。 Of the consumables information shown in FIG. 4, the inter-disk movement permission setting may be set to enable / disable movement control by, for example, the operation unit 201 downloading parameters from an external medium or an external system. As shown in FIG. 5 and the like, the user may operate the input unit 118 to set whether or not the movement control is possible.
　図５に示すディスク間移動設定画面９００は表示部１１１に表示される画面であり、移動制御の可／不可自体の設定を行うための選択領域９０１、消耗品あるいは装置メンテナンス部品の種別ごとに移動制御の可／不可の設定を行うための選択領域９０２が表示されており、登録ボタン９０３を押下することでユーザが選択された設定が装置に反映される。ディスク間移動設定画面９００を閉じる場合はキャンセルボタン９０４を押下する。 The inter-disk movement setting screen 900 shown in FIG. 5 is a screen displayed on the display unit 111, and is moved according to the selection area 901 for setting the movement control enable / disable itself, and the type of consumables or equipment maintenance parts. A selection area 902 for setting control enable / disable is displayed, and the setting selected by the user is reflected in the device by pressing the registration button 903. To close the disk-to-disk movement setting screen 900, press the cancel button 904.
　図６に示す消耗品リスト画面５００は、図５と同様に表示部１１１に表示される画面であり、消耗品あるいは装置メンテナンス部品の消耗品一覧表示エリア５０１ごとの移動の可／不可を設定する画面であり、消耗品移動許可設定ボックス５０２のチェックの有無に連動して可／不可が設定される。 The consumables list screen 500 shown in FIG. 6 is a screen displayed on the display unit 111 as in FIG. 5, and it is possible to set whether or not to move each consumables list display area 501 of consumables or equipment maintenance parts. On the screen, enable / disable is set in conjunction with whether or not the consumables movement permission setting box 502 is checked.
　なお、図６に示す消耗品一覧表示エリア５０１のうち、“名称”には、洗剤や項目名称が表示される。例えば、膵臓関連のＲＤ試薬であれば、「Ｅｃｏ　Ｔａｒｇｅｎｔ」、「ＮＡＯＨＤ」、「ＨｂＡ１ｃ」、「アルブミン（ＡＬＢ）」、「クレアチンキナーゼ（ＣＫ）項目」等である。 In the consumables list display area 501 shown in FIG. 6, the detergent and item names are displayed in the "name". For example, in the case of pancreas-related RD reagent, "Eco Targent", "NAOHD", "HbA1c", "albumin (ALB)", "creatine kinase (CK) item" and the like.
　処理Ｓ３０２で消耗品の移動によって分析可能と判断された場合には、消耗品に必要な時間の算出を行う（処理Ｓ３０３）。 If it is determined in process S302 that analysis is possible due to the movement of consumables, the time required for consumables is calculated (process S303).
　この時、消耗品情報保持部２０５および制御情報保持部２０９を参照し、移動が必要な消耗品に既に使用予定が入っているかを確認する。使用予定が入っていないもしくは使用予定までに消耗品を元の試薬ディスクに戻せるのであれば消耗品移動に係る時間を、使用予定が入っているかつ使用予定までに消耗品を元の試薬ディスクに戻せないのであれば、消耗品使用予定後から消耗品移動に係る時間を算出する。 At this time, refer to the consumables information holding unit 205 and the control information holding unit 209, and confirm whether the consumables that need to be moved are already scheduled to be used. If the consumables are not scheduled to be used or the consumables can be returned to the original reagent disc by the scheduled use, the time required for moving the consumables should be reduced to the original reagent discs if the consumables are scheduled to be used and the consumables should be returned to the original reagent disc by the scheduled use. If it cannot be returned, calculate the time required to move the consumables after the consumables are scheduled to be used.
　処理Ｓ３０３での算出後、あるいは処理Ｓ３０２で消耗品の移動によって分析可能でないと判断された場合は、次いで、計画実行部２０６は、タイミングを遅らせることで分析可能となるか否かを判断する（処理Ｓ３０４）。 After the calculation in the process S303, or when it is determined in the process S302 that the analysis is not possible due to the movement of consumables, the plan execution unit 206 then determines whether or not the analysis can be performed by delaying the timing (. Process S304).
　処理Ｓ３０４で分注のタイミングを遅らせることで分析可能と判断された場合には、分析開始までの待機時間を算出する（処理Ｓ３０５）。 If it is determined in process S304 that analysis is possible by delaying the timing of dispensing, the waiting time until the start of analysis is calculated (process S305).
　算出後、あるいは処理Ｓ３０４で分注のタイミングを遅らせることでも分析可能ではないと判断された場合は、次いで、計画実行部２０６は、処理Ｓ３０２乃至処理Ｓ３０５での処理に基づいて、依頼された分析が実行可能であるか否かを判断する（処理Ｓ３０６）。 If it is determined that the analysis is not possible after the calculation or by delaying the dispensing timing in the process S304, the plan execution unit 206 then requests the analysis based on the process in the process S302 to the process S305. Determines whether or not is feasible (process S306).
　処理Ｓ３０６で分析可能と判断された場合には、分析動作計画部２０７に指示を行い分析動作の計画を実施する（処理Ｓ３１２）。実施後、本フローを終了する。 If it is determined in process S306 that analysis is possible, an instruction is given to the analysis operation planning unit 207 to plan the analysis operation (process S312). After the implementation, this flow is terminated.
　また、処理Ｓ３０６で分析不可能と判断された場合には、当該分析の継続を不可能と判断し、分析情報保持部２０４の更新、および送信部２０３を介して操作部２０１への通信を実施（処理Ｓ３１３）して、本フローを終了する。 If it is determined in the process S306 that the analysis cannot be continued, it is determined that the analysis cannot be continued, the analysis information holding unit 204 is updated, and the operation unit 201 is communicated via the transmitting unit 203. (Process S313) to end this flow.
　更に、計画実行部２０６は、対応する試薬ディスクだけで消耗品が不足している場合でも、ディスク間移動許可設定４０６が許可の消耗品を充てることで分析が可能となると判断された場合や、分注タイミングを遅らせることで分析が可能となると判断された場合には、分析不可能とは判断せず、処理Ｓ３０７に処理を進める。 Further, even if the planning execution unit 206 is short of consumables only with the corresponding reagent discs, the plan execution unit 206 may determine that the analysis can be performed by allocating the consumables permitted by the inter-disc movement permission setting 406. If it is determined that the analysis is possible by delaying the dispensing timing, it is not determined that the analysis is impossible, and the process proceeds to the process S307.
　次いで、計画実行部２０６は、処理Ｓ３０３で算出した移動時間および処理Ｓ３０５で算出した待機時間を比較し、移動時間が待機時間より短いか否かを判断する（処理Ｓ３０７）。移動時間が待機時間より短いと判断されたときは消耗品の移動計画を作成、実行すべく処理を処理Ｓ３０８に進める。また、移動時間が待機時間以上であると判断されたときは消耗品の搬入を待つ分析計画を作成、実行すべく処理を処理Ｓ３０９に進める。 Next, the plan execution unit 206 compares the travel time calculated in the process S303 with the waiting time calculated in the process S305, and determines whether or not the travel time is shorter than the standby time (process S307). When it is determined that the movement time is shorter than the standby time, a movement plan for consumables is created and the process proceeds to the process S308 for execution. Further, when it is determined that the moving time is longer than the waiting time, an analysis plan for waiting for the delivery of consumables is created, and the process proceeds to the process S309 for execution.
　処理Ｓ３０７で移動時間が待機時間以上である、すなわち、分注タイミングの遅延の方が消耗品の移動に比べて分析開始までに要する時間が短いと判断された場合には、計画実行部２０６は、当該分析を行うために必要な試薬容器の移動計画の作成を試薬移動動作計画部２０８に指示する（処理Ｓ３０９）。移動計画に続き、分析動作計画部２０７に指示を行い分析動作の計画を実施する。 When it is determined in the process S307 that the movement time is longer than the standby time, that is, the delay in the dispensing timing is shorter than the movement of the consumables, the planning execution unit 206 determines that the time required to start the analysis is shorter. , Instruct the reagent movement operation planning unit 208 to create a movement plan of the reagent container necessary for performing the analysis (process S309). Following the movement plan, an instruction is given to the analysis operation planning unit 207 to carry out the analysis operation plan.
　次いで、計画実行部２０６は、処理Ｓ３０９の処理により移動させた試薬容器などの消耗品を移動元の試薬ディスクに戻すための移動動作が必要か否かの判断を行う（処理Ｓ３１０）。例えば、制御情報保持部２０９を参照し、移動が必要な消耗品に既に使用予定が入っているかによって判断する。また、使用予定だけではなく、消耗品情報保持部２０５を参照して当該試薬容器と関連する消耗品数で判別したり、直前一定期間の各ディスクでの当該試薬の使用率で判別したり、ユーザ指定の設定を参照して判別する方法を追加してもよく、条件は１つに限られない。 Next, the planning execution unit 206 determines whether or not a moving operation for returning the consumables such as the reagent container moved by the processing of the processing S309 to the reagent disk of the moving source is necessary (processing S310). For example, the control information holding unit 209 is referred to, and it is determined whether or not the consumables that need to be moved are already scheduled to be used. In addition to the usage schedule, the user can also refer to the consumables information holding unit 205 to determine the number of consumables related to the reagent container, or determine the usage rate of the reagent on each disk for a certain period immediately before. A method for determining by referring to the specified setting may be added, and the condition is not limited to one.
　処理Ｓ３１０において移動動作が不要と判断された場合には、本フローを終了する。 If it is determined in the process S310 that the movement operation is unnecessary, this flow is terminated.
　これに対し、処理Ｓ３１０で試薬容器を移動元の試薬ディスクに戻すための移動動作が必要と判断された場合には、計画実行部２０６は、試薬移動動作計画部２０８に指示を行い、処理Ｓ３０９で実施した分析計画の後に、試薬容器の移動計画を実施する（処理Ｓ３１１）。実施後、本フローを終了する。 On the other hand, when it is determined in the process S310 that a moving operation for returning the reagent container to the moving source reagent disk is necessary, the planning execution unit 206 gives an instruction to the reagent moving operation planning unit 208, and the processing S309 After the analysis plan carried out in (Process S311), the reagent container movement plan is carried out. After the implementation, this flow is terminated.
　また、処理Ｓ３０７で移動時間が待機時間より短いと判断された場合には、計画実行部２０６は、処理Ｓ３０５で算出した指定時間後に分析動作計画部２０７に指示を行い分析動作の計画を実施する（処理Ｓ３０８）。実施後、本フローを終了する。遅延させる指定時間中に、分析を停止させる必要はなく、当該分析と関係のない項目の分析は可能である。 If the process S307 determines that the travel time is shorter than the standby time, the plan execution unit 206 issues an instruction to the analysis operation planning unit 207 after the designated time calculated in the process S305 to plan the analysis operation. (Processing S308). After the implementation, this flow is terminated. It is not necessary to stop the analysis during the specified time to be delayed, and it is possible to analyze items that are not related to the analysis.
　次に、本実施例の効果について説明する。 Next, the effect of this embodiment will be described.
　上述した本発明の実施例１の自動分析装置１００は、それぞれが並列して動作する、１つのモジュール内に複数配置された試薬ディスク１０１ａ，１０１ｂと、試薬ディスク１０１ａ，１０１ｂ内に保管可能な分析に必要な消耗品あるいは装置メンテナンス部品を装置内への試薬搬入出エリア１０９から試薬ディスク１０１ａ，１０１ｂへ搬送させるとともに、複数の試薬ディスク１０１ａ，１０１ｂの間で移動させる試薬搬送機構１０８と、消耗品あるいは装置メンテナンス部品を、消耗品あるいは装置メンテナンス部品を有している試薬ディスク１０１ａ，１０１ｂから、消耗品あるいは装置メンテナンス部品を有していない動作計画対象の試薬ディスク１０１ａ，１０１ｂへ移動させる移動制御を実行する制御部１１９と、を備えている。 The above-mentioned automatic analyzer 100 of the first embodiment of the present invention operates in parallel with a plurality of reagent disks 101a and 101b arranged in one module and analysis that can be stored in the reagent disks 101a and 101b. Consumables or equipment maintenance parts required for Alternatively, movement control is performed to move the device maintenance parts from the reagent disks 101a and 101b having consumables or device maintenance parts to the reagent disks 101a and 101b to be operated without consumables or device maintenance parts. It includes a control unit 119 for execution.
　これによって、複数の試薬ディスク１０１ａ，１０１ｂに搭載されなくてはいけなかった試薬容器や装置メンテナンス用部品を試薬ディスク１０１ａ，１０１ｂのいずれかのみに搭載することで対応できるようになり、複数の試薬ディスク１０１ａ，１０１ｂの搭載効率を向上することができるとともに、ユーザの投入、搬出などの操作負荷を軽減することができる。 As a result, the reagent container and equipment maintenance parts that had to be mounted on the plurality of reagent discs 101a and 101b can be mounted on only one of the reagent discs 101a and 101b, and the plurality of reagents can be dealt with. The mounting efficiency of the disks 101a and 101b can be improved, and the operation load such as loading and unloading of the user can be reduced.
　また、消耗品あるいは装置メンテナンス部品の移動制御の可／不可を設定するディスク間移動設定画面９００、消耗品リスト画面５００を更に備えたため、装置の運用に応じた移動の可／不可の制御を容易に選択することができ、効果的な装置運用を図ることができるとともにユーザの負荷をより軽減することができる。 In addition, a disk-to-disk movement setting screen 900 for setting the possibility / non-movement control of consumables or equipment maintenance parts and a consumables list screen 500 are further provided, so that it is easy to control the movement control according to the operation of the device. It is possible to select the above, and it is possible to plan effective device operation and further reduce the load on the user.
　更に、ディスク間移動設定画面９００、消耗品リスト画面５００では、消耗品あるいは装置メンテナンス部品の種別ごと，項目ごとの移動の可／不可を設定可能であることで、より細かな装置の運用条件に応じた設定が可能となり、更なる負荷軽減を図ることができる。 Further, on the disk-to-disk movement setting screen 900 and the consumables list screen 500, it is possible to set whether or not to move for each type of consumable or device maintenance component and for each item, so that the operation conditions of the device can be more detailed. It is possible to make settings according to the situation, and it is possible to further reduce the load.
　また、消耗品あるいは装置メンテナンス部品の移動制御の可／不可の設定を外部システムないし外部メディアの情報から設定することにより、装置に詳しくないユーザであっても上述の操作負荷の軽減の効果を得ることができる。 Further, by setting the enable / disable of the movement control of consumables or equipment maintenance parts from the information of the external system or the external media, even a user who is not familiar with the equipment can obtain the above-mentioned effect of reducing the operation load. be able to.
　更に、制御部１１９は、消耗品の移動に必要な移動時間、および分注タイミングを遅らせる待機に必要な待機時間を算出し、移動時間が待機時間より短いときは消耗品の移動を実行する分析計画とし、移動時間が待機時間以上のときは消耗品の搬入を待つ分析計画とすることで、分析結果が得られるまでの時間が必要以上に長くなってしまうことを避けることができ、自動分析装置１００の稼働効率の向上を図ることができる。 Further, the control unit 119 calculates the movement time required for moving the consumables and the waiting time required for waiting to delay the dispensing timing, and when the moving time is shorter than the waiting time, the analysis executes the movement of the consumables. By making a plan and making an analysis plan that waits for the delivery of consumables when the travel time is longer than the waiting time, it is possible to prevent the time until the analysis result is obtained from becoming longer than necessary, and automatic analysis. It is possible to improve the operating efficiency of the device 100.
　また、制御部１１９は、消耗品の返却条件に一致しているか否かを判断し、一致しているときは移動させた消耗品をもとの試薬ディスク１０１ａ，１０１ｂへ移動させることにより、分析計画などに応じたより細かな消耗品の移動制御が可能となる。 Further, the control unit 119 determines whether or not the consumables return conditions are met, and if they are matched, the moved consumables are moved to the original reagent disks 101a and 101b for analysis. It is possible to control the movement of consumables in more detail according to the plan.
　＜実施例２＞　
　本発明の実施例２の自動分析装置について図７乃至図９を用いて説明する。図７は本実施例２の自動分析装置における装置メンテナンス実行画面例を示す図、図８は制御部のソフト構造を概略的に示す図、図９は試薬移動を含む装置メンテナンス制御計画の作成手順を示すフローチャートである。 <Example 2>
The automatic analyzer according to the second embodiment of the present invention will be described with reference to FIGS. 7 to 9. FIG. 7 is a diagram showing an example of an apparatus maintenance execution screen in the automated analyzer of the second embodiment, FIG. 8 is a diagram schematically showing a soft structure of a control unit, and FIG. 9 is a procedure for creating an apparatus maintenance control plan including reagent movement. It is a flowchart which shows.
　上記の実施例１は、分析動作における複数の試薬ディスク１０１ａ，１０１ｂ間での消耗品の共有に係る態様であったのに対し、本実施例では、消耗品ないし装置メンテナンス用部品の共有を装置メンテナンスにおいて図る態様について説明する。 While the above-mentioned Example 1 was an embodiment relating to the sharing of consumables among a plurality of reagent disks 101a and 101b in the analysis operation, in the present embodiment, the consumables or equipment maintenance parts are shared. An aspect to be planned in maintenance will be described.
　本実施例では、例えば図７に示すように、試薬ディスク１０１ａ，１０１ｂに搭載された消耗品や装置メンテナンス用部品を使用する装置メンテナンスの実行画面６００に、上述の装置メンテナンスで使用する消耗品ないし装置メンテナンス用部品のリスト６０１が表示される。このリスト６０１で、該当する消耗品ないし装置メンテナンス用部品が複数の試薬ディスク１０１ａ，１０１ｂに載積されている場合にはユーザが適宜操作可能なドロップボックス６０２等の手段によって選択する。 In this embodiment, for example, as shown in FIG. 7, the consumables used in the above-mentioned device maintenance or the consumables used in the above-mentioned device maintenance are displayed on the device maintenance execution screen 600 using the consumables and the device maintenance parts mounted on the reagent disks 101a and 101b. A list of equipment maintenance parts 601 is displayed. In this list 601 when the corresponding consumables or equipment maintenance parts are loaded on a plurality of reagent disks 101a and 101b, they are selected by means such as a drop box 602 that can be appropriately operated by the user.
　例えば、装置メンテナンスの実行画面６００では、ドロップボックス６０２にて選択された消耗品によって必要となる移動時間を算出し、上述の装置メンテナンスの実行にかかる時間に加算したうえで、装置メンテナンスの実行画面６００に装置メンテナンス実行時間６０３を表示して、実行ボタン６０４を押下することでユーザが選択した装置メンテナンスが実行される。実行画面６００を閉じる場合はキャンセルボタン６０５を押下する。 For example, on the device maintenance execution screen 600, the travel time required for the consumables selected in the drop box 602 is calculated, added to the time required for executing the device maintenance described above, and then the device maintenance execution screen is displayed. The device maintenance execution time 603 is displayed on the 600, and the device maintenance selected by the user is executed by pressing the execute button 604. To close the execution screen 600, press the cancel button 605.
　なお、本実施例における消耗品は例えば特別洗浄用の洗剤であり、装置メンテナンス部品は例えば試薬ディスク１０１ａ，１０１ｂ内の汚れや不純物を拭き取るワイパーなどである。 The consumable item in this embodiment is, for example, a detergent for special cleaning, and the device maintenance component is, for example, a wiper for wiping off dirt and impurities in the reagent disks 101a and 101b.
　また、図８は、上述の装置メンテナンスに係る自動分析装置の制御部１１９のソフト構造を概略的に示す図である。 Further, FIG. 8 is a diagram schematically showing the soft structure of the control unit 119 of the automatic analyzer related to the above-mentioned equipment maintenance.
　本実施例の制御部７００は、試薬搬送機構１０８の制御に関連するソフトウェア機能として、受信部７０２、送信部７０３、装置メンテナンス情報保持部７０４、消耗品情報保持部７０５、計画実行部７０６、装置メンテナンス動作計画部７０７、試薬移動動作計画部７０８、制御情報保持部７０９、制御実行部７１０、機構制御部７１１ａ，７１１ｂ，７１１ｃを備えている。 The control unit 700 of this embodiment has a receiving unit 702, a transmitting unit 703, an apparatus maintenance information holding unit 704, a consumables information holding unit 705, a planning execution unit 706, and an apparatus as software functions related to the control of the reagent transport mechanism 108. It includes a maintenance operation planning unit 707, a reagent movement operation planning unit 708, a control information holding unit 709, a control execution unit 710, and a mechanism control unit 711a, 711b, 711c.
　装置メンテナンス情報保持部７０４は、受信部７０２を介して操作部７０１から設定された、装置メンテナンスを行うために必要な情報を保持する。本実施例では、装置メンテナンス情報保持部７０４の情報は、装置メンテナンスに使用する試薬情報を含み、計画実行部７０６により参照される。 The device maintenance information holding unit 704 holds the information necessary for performing the device maintenance set from the operation unit 701 via the receiving unit 702. In this embodiment, the information of the device maintenance information holding unit 704 includes the reagent information used for the device maintenance and is referred to by the planning execution unit 706.
　計画実行部７０６は、上述の装置メンテナンス情報保持部７０４および上述の消耗品情報保持部７０５より装置メンテナンスに係る情報を参照し、装置メンテナンス動作計画部７０７および試薬移動動作計画部７０８を実行する。装置メンテナンス動作計画部７０７および試薬移動動作計画部７０８の実行結果は、各機構の制御情報として制御情報保持部７０９に保持される。上記計画実行で用いられる計画ロジックの詳細は図９以降を用いて後ほど詳しく説明する。 The planning execution unit 706 refers to the information related to the equipment maintenance from the above-mentioned equipment maintenance information holding unit 704 and the above-mentioned consumables information holding unit 705, and executes the equipment maintenance operation planning unit 707 and the reagent transfer operation planning unit 708. The execution results of the device maintenance operation planning unit 707 and the reagent movement operation planning unit 708 are held in the control information holding unit 709 as control information of each mechanism. The details of the planning logic used in the above planning execution will be described in detail later with reference to FIGS. 9 and later.
　図２および図８に示したその他の構成・動作は前述した実施例１の自動分析装置、および自動分析装置の運転方法と同じ構成・動作であり、詳細は省略する。また、別ソフトウェアとして記載した上述の分析情報保持部２０４と装置メンテナンス情報保持部７０４や、分析動作計画部２０７と装置メンテナンス動作計画部７０７は、図３乃至図９に示す計画ロジックを担っていれば同一ソフトウェアとして実現することができる。 The other configurations / operations shown in FIGS. 2 and 8 are the same configurations / operations as the operation method of the automated analyzer and the automated analyzer of the first embodiment described above, and details thereof will be omitted. Further, the above-mentioned analysis information holding unit 204 and device maintenance information holding unit 704 described as separate software, and the analysis operation planning unit 207 and device maintenance operation planning unit 707 are responsible for the planning logic shown in FIGS. 3 to 9. If so, it can be realized as the same software.
　次いで、制御部７００における計画実行部７０６の計画ロジックの詳細について図９を用いて説明する。 Next, the details of the planning logic of the planning execution unit 706 in the control unit 700 will be described with reference to FIG.
　図９に示すように、最初に、計画実行部７０６は、消耗品情報保持部７０５より、装置メンテナンス情報保持部７０４に登録された分析を行うための必要な項目の消耗品情報を参照する（処理Ｓ８０１）。 As shown in FIG. 9, first, the plan execution unit 706 refers from the consumables information holding unit 705 to the consumables information of the items necessary for performing the analysis registered in the device maintenance information holding unit 704 (the consumables information holding unit 705). Process S801).
　参照した情報を元にして、計画実行部７０６は、装置内の消耗品ないし装置メンテナンス用部品が装置メンテナンスの実行に適しているかの確認を行う（処理Ｓ８０２）。 Based on the referenced information, the plan execution unit 706 confirms whether the consumables or equipment maintenance parts in the equipment are suitable for executing the equipment maintenance (process S802).
　消耗品ないし装置メンテナンス用部品の移動なく装置メンテナンス動作が実行可能であれば、次のステップとして処理Ｓ８０３を実行する。また、移動を行ったとしても装置メンテナンス動作が実行不可能である場合には、次のステップとして処理Ｓ８０４を実行する。更に、移動を行うことで装置メンテナンス動作が実行可能となる場合には、次のステップとして処理Ｓ８０５を実行する。 If the device maintenance operation can be executed without moving consumables or equipment maintenance parts, the process S803 is executed as the next step. If the device maintenance operation cannot be executed even if the device is moved, the process S804 is executed as the next step. Further, when the device maintenance operation can be executed by moving, the process S805 is executed as the next step.
　また、処理Ｓ８０２においては、上述の装置メンテナンスの実行画面６００等や上述の消耗品リスト画面５００でユーザが適宜設定した情報を操作部７０１から受け取り、条件に加えることができる。 Further, in the process S802, the information appropriately set by the user on the above-mentioned device maintenance execution screen 600 and the above-mentioned consumables list screen 500 can be received from the operation unit 701 and added to the conditions.
　処理Ｓ８０２において移動なく装置メンテナンス動作が実行可能であると判断されたときは、計画実行部７０６は、装置メンテナンス動作計画部７０７に指示を行い装置メンテナンス動作の計画を実施する（処理Ｓ８０３）。実施後、本フローを終了する。 When it is determined in the process S802 that the device maintenance operation can be executed without movement, the plan execution unit 706 issues an instruction to the device maintenance operation planning unit 707 to execute the device maintenance operation plan (process S803). After the implementation, this flow is terminated.
　また、処理Ｓ８０２において移動させても装置メンテナンス動作が実行不可能と判断されたときは、計画実行部７０６は、当該分析の継続を不可能と判断し、装置メンテナンス情報保持部７０４の更新、および送信部７０３を介して操作部７０１への通信を実施（処理Ｓ８０４）して、本フローを終了する。 Further, when it is determined that the device maintenance operation cannot be executed even if the device is moved in the process S802, the plan execution unit 706 determines that the analysis cannot be continued, updates the device maintenance information holding unit 704, and updates the device maintenance information holding unit 704. Communication to the operation unit 701 via the transmission unit 703 is performed (process S804), and this flow ends.
　更に、処理Ｓ８０２において移動に依ってメンテナンスが実行可能であると判断されたときは、計画実行部７０６は、当該装置メンテナンスを行うために必要な消耗品ないしは装置メンテナンス用部品の移動計画の作成を試薬移動動作計画部７０８に指示する（処理Ｓ８０５）。移動計画の作成に続き、処理Ｓ８０５の完了後は、装置メンテナンス動作計画部７０７に指示を行い、装置メンテナンス動作の計画を実施する（処理Ｓ８０５）。 Further, when it is determined in the process S802 that maintenance can be performed by movement, the plan execution unit 706 creates a movement plan for consumables or equipment maintenance parts necessary for performing the equipment maintenance. Instruct the reagent transfer operation planning unit 708 (process S805). Following the creation of the movement plan, after the completion of the process S805, an instruction is given to the device maintenance operation planning unit 707 to implement the device maintenance operation plan (process S805).
　その後、計画実行部７０６は、処理Ｓ８０５に次いで、当該装置メンテナンスのために移動する試薬容器を元の試薬ディスク１０１ａ，１０１ｂへ戻すための移動計画を試薬移動動作計画部７０８に指示を行い実施する（処理Ｓ８０６）。この処理Ｓ８０６は実施例１の図３で説明した処理Ｓ３１０，Ｓ３１１とは異なり、判断無しで元の試薬ディスク１０１ａ，１０１ｂへ消耗品あるいは装置メンテナンス部品を移動させるものとするが、処理Ｓ３１０と同様に判断を行うものであってもよい。処理Ｓ８０６の実施後、本フローを終了する。 After that, the planning execution unit 706 instructs the reagent moving operation planning unit 708 to carry out a moving plan for returning the reagent container to be moved for the maintenance of the apparatus to the original reagent disks 101a and 101b after the processing S805. (Processing S806). This process S806 is different from the processes S310 and S311 described in FIG. 3 of the first embodiment, and consumables or equipment maintenance parts are moved to the original reagent disks 101a and 101b without judgment, but the same as the process S310. It may be the one that makes a judgment. After the execution of the process S806, this flow is terminated.
　その他の構成・動作は前述した実施例１の自動分析装置と略同じ構成・動作であり、詳細は省略する。 Other configurations / operations are substantially the same as those of the automated analyzer of the first embodiment described above, and details are omitted.
　本発明の実施例２の自動分析装置においても、前述した実施例１の自動分析装置とほぼ同様な効果が得られる。 The automatic analyzer of the second embodiment of the present invention also has almost the same effect as the above-mentioned automatic analyzer of the first embodiment.
　特に、制御部１１９は、装置メンテナンス実行条件を確認し、消耗品あるいは装置メンテナンス部品の移動に依ってメンテナンスが実行可能であると判断されたときは、消耗品あるいは装置メンテナンス部品の移動を実行する装置メンテナンス計画とすることにより、装置メンテナンスに要するユーザの操作負荷を従来に比べて軽減することができる。 In particular, the control unit 119 confirms the equipment maintenance execution conditions, and when it is determined that maintenance can be executed by moving the consumables or the equipment maintenance parts, the control unit 119 executes the movement of the consumables or the equipment maintenance parts. By making the device maintenance plan, it is possible to reduce the user's operation load required for the device maintenance as compared with the conventional case.
　また、制御部１１９は、移動付きの装置メンテナンス計画の実行後に、試薬ディスク１０１ａ，１０１ｂへ消耗品あるいは装置メンテナンス部品を再度移動させることで、分析計画などに応じたより細かな消耗品の移動制御が可能となる。 Further, the control unit 119 moves the consumables or the device maintenance parts to the reagent disks 101a and 101b again after executing the device maintenance plan with the movement, so that the movement control of the consumables can be finely controlled according to the analysis plan and the like. It will be possible.
　＜その他＞　
　なお、本発明は、上記の実施例に限定されるものではなく、様々な変形例が含まれる。上記の実施例は本発明を分かりやすく説明するために詳細に説明したものであり、必ずしも説明した全ての構成を備えるものに限定されるものではない。 <Others>
The present invention is not limited to the above examples, and includes various modifications. The above-mentioned examples have been described in detail in order to explain the present invention in an easy-to-understand manner, and are not necessarily limited to those having all the described configurations.
　また、ある実施例の構成の一部を他の実施例の構成に置き換えることも可能であり、また、ある実施例の構成に他の実施例の構成を加えることも可能である。また、各実施例の構成の一部について、他の構成の追加・削除・置換をすることも可能である。 It is also possible to replace a part of the configuration of one embodiment with the configuration of another embodiment, and it is also possible to add the configuration of another embodiment to the configuration of one embodiment. Further, it is also possible to add / delete / replace a part of the configuration of each embodiment with another configuration.
１００…自動分析装置
１０１ａ，１０１ｂ…試薬ディスク
１０２…反応ディスク
１０３ａ，１０３ｂ，１０３ｃ，１０３ｄ…試薬分注プローブ
１０４ａ，１０４ｂ…検体分注プローブ
１０５…光源
１０６…多波長光度計
１０７…反応容器洗浄機構
１０８…試薬搬送機構（搬送部）
１０９…試薬搬入出エリア（設置位置）
１１０…検体搬送機構
１１１…表示部
１１２…検体容器
１１３ａ，１１３ｂ…試薬ディスク内の試薬容器
１１４…試薬容器設置エリア
１１５…反応容器
１１６ａ，１１６ｂ…ネットワーク回線
１１７…操作部
１１８…入力部
１１９…制御部
２００，７００…制御部
２０１，７０１…操作部
２０２，７０２…受信部
２０３，７０３…送信部
２０４…分析情報保持部
２０５，７０５…消耗品情報保持部
２０６，７０６…計画実行部
２０７…分析動作計画部
２０８，７０８…試薬移動動作計画部
２０９，７０９…制御情報保持部
２１０，７１０…制御実行部
２１１ａ，７１１ａ…試薬搬送機構制御部
２１１ｂ，７１１ｂ…試薬ディスク制御部
２１１ｃ，７１１ｃ…試薬プローブ制御部
４０１…消耗品Ｎｏ
４０２…消耗品名称
４０３…消耗品使用期限
４０４…消耗品積載場所
４０５…消耗品残量
４０６…ディスク間移動許可設定
５００…消耗品リスト画面
５０１…消耗品一覧表示エリア
５０２…消耗品移動許可設定ボックス
６００…装置メンテナンスの実行画面
６０１…リスト
６０２…ドロップボックス
６０３…装置メンテナンス実行時間
６０４…実行ボタン
６０５…キャンセルボタン
７０４…装置メンテナンス情報保持部
７０７…装置メンテナンス動作計画部
９００…ディスク間移動設定画面（選択部）
９０１…選択領域
９０２…選択領域
９０３…登録ボタン
９０４…キャンセルボタン 100 ... Automatic analyzer 101a, 101b ... Reagent disk 102 ... Reaction disk 103a, 103b, 103c, 103d ... Reagent dispensing probe 104a, 104b ... Sample dispensing probe 105 ... Light source 106 ... Multi-wavelength photometer 107 ... Reaction vessel cleaning mechanism 108 ... Reagent transfer mechanism (transport section)
109 ... Reagent loading / unloading area (installation position)
110 ... Specimen transport mechanism 111 ... Display unit 112 ... Specimen container 113a, 113b ... Reagent container in the reagent disk 114 ... Reagent container installation area 115 ... Reaction container 116a, 116b ... Network line 117 ... Operation unit 118 ... Input unit 119 ... Control Units 200, 700 ... Control units 201, 701 ... Operation units 202, 702 ... Receiver units 203, 703 ... Transmission unit 204 ... Analysis information holding units 205, 705 ... Consumables information holding units 206, 706 ... Planning execution unit 207 ... Analysis Operation planning unit 208, 708 ... Reagent movement operation planning unit 209, 709 ... Control information holding unit 210, 710 ... Control execution unit 211a, 711a ... Reagent transfer mechanism control unit 211b, 711b ... Reagent disk control unit 211c, 711c ... Reagent probe Control unit 401 ... Consumables No.
402 ... Consumables name 403 ... Consumables expiration date 404 ... Consumables loading location 405 ... Consumables remaining amount 406 ... Disc-to-disk movement permission setting 500 ... Consumables list screen 501 ... Consumables list display area 502 ... Consumables movement permission setting Box 600 ... Device maintenance execution screen 601 ... List 602 ... Drop box 603 ... Device maintenance execution time 604 ... Execution button 605 ... Cancel button 704 ... Device maintenance information holding unit 707 ... Device maintenance operation planning unit 900 ... Disk-to-disk movement setting screen (Selection section)
901 ... Selection area 902 ... Selection area 903 ... Registration button 904 ... Cancel button

Claims (9)

  1. 　それぞれが並列して動作する、１つのモジュール内に複数配置された試薬ディスクと、
    　前記試薬ディスク内に保管可能な分析に必要な消耗品あるいは装置メンテナンス部品を装置内への設置位置から前記試薬ディスクへ搬送させるとともに、複数の前記試薬ディスクの間で移動させる搬送部と、
    　前記消耗品あるいは前記装置メンテナンス部品を、前記消耗品あるいは前記装置メンテナンス部品を有している前記試薬ディスクから、前記消耗品あるいは前記装置メンテナンス部品を有していない動作計画対象の試薬ディスクへ移動させる移動制御を実行する制御部と、を備えた
    　ことを特徴とする自動分析装置。     Multiple reagent disks arranged in one module, each operating in parallel,
    A transport unit that transports consumables or equipment maintenance parts necessary for analysis that can be stored in the reagent disc from the installation position in the equipment to the reagent disc, and also moves between the plurality of reagent discs.
    The consumable or the device maintenance component is moved from the reagent disk having the consumable or the device maintenance component to the reagent disk subject to the operation plan which does not have the consumable or the device maintenance component. An automatic analyzer characterized by having a control unit that executes movement control.
  2. 　請求項１に記載の自動分析装置において、
    　前記消耗品あるいは前記装置メンテナンス部品の移動制御の可／不可を設定する選択部を更に備えた
    　ことを特徴とする自動分析装置。     In the automatic analyzer according to claim 1,
    An automated analyzer further comprising a selection unit for setting whether or not movement control of the consumables or equipment maintenance parts is possible.
  3. 　請求項２に記載の自動分析装置において、
    　前記選択部では、前記消耗品あるいは前記装置メンテナンス部品の種別ごと，項目ごとの移動の可／不可を設定可能である
    　ことを特徴とする自動分析装置。     In the automatic analyzer according to claim 2,
    The selection unit is an automatic analyzer characterized in that it is possible to set whether or not movement is possible for each type of consumable item or equipment maintenance component, and for each item.
  4. 　請求項１に記載の自動分析装置において、
    　前記消耗品あるいは前記装置メンテナンス部品の移動制御の可／不可の設定を外部システムないし外部メディアの情報から設定する
    　ことを特徴とする自動分析装置。     In the automatic analyzer according to claim 1,
    An automatic analyzer characterized in that the movement control of the consumables or the maintenance parts of the equipment is set to be possible / uncontrollable from the information of the external system or the external media.
  5. 　請求項１に記載の自動分析装置において、
    　前記制御部は、前記消耗品の移動に必要な移動時間、および分注タイミングを遅らせる待機に必要な待機時間を算出し、前記移動時間が前記待機時間より短いときは前記消耗品の移動を実行する分析計画とし、前記移動時間が前記待機時間以上のときは前記消耗品の搬入を待つ分析計画とする
    　ことを特徴とする自動分析装置。     In the automatic analyzer according to claim 1,
    The control unit calculates the moving time required for moving the consumables and the waiting time required for waiting to delay the dispensing timing, and when the moving time is shorter than the waiting time, the consumables are moved. An automatic analyzer characterized in that the analysis plan is to wait for the consumables to be brought in when the travel time is longer than the standby time.
  6. 　請求項１に記載の自動分析装置において、
    　前記制御部は、前記消耗品の返却条件に一致しているか否かを判断し、一致しているときは移動させた前記消耗品をもとの前記試薬ディスクへ移動させる
    　ことを特徴とする自動分析装置。     In the automatic analyzer according to claim 1,
    The control unit determines whether or not the conditions for returning the consumables are met, and if they match, the automatic control unit moves the moved consumables to the original reagent disk. Analysis equipment.
  7. 　請求項１に記載の自動分析装置において、
    　前記制御部は、装置メンテナンス実行条件を確認し、前記消耗品あるいは前記装置メンテナンス部品の移動に依ってメンテナンスが実行可能であると判断されたときは、前記消耗品あるいは前記装置メンテナンス部品の移動を実行する装置メンテナンス計画とする
    　ことを特徴とする自動分析装置。     In the automatic analyzer according to claim 1,
    The control unit confirms the equipment maintenance execution conditions, and when it is determined that maintenance can be executed by moving the consumables or the equipment maintenance parts, the control unit moves the consumables or the equipment maintenance parts. An automated analyzer characterized by an instrument maintenance plan to be performed.
  8. 　請求項７に記載の自動分析装置において、
    　前記制御部は、移動付きの前記装置メンテナンス計画の実行後に、前記試薬ディスクへ前記消耗品あるいは前記装置メンテナンス部品を再度移動させる
    　ことを特徴とする自動分析装置。     In the automatic analyzer according to claim 7,
    The control unit is an automatic analyzer characterized in that the consumables or the equipment maintenance parts are moved again to the reagent disk after the execution of the equipment maintenance plan with movement.
  9. 　請求項１に記載の自動分析装置において、
    　前記消耗品は、分析に用いる試薬、あるいは分析後に使用する洗浄液である
    　ことを特徴とする自動分析装置。     In the automatic analyzer according to claim 1,
    The consumable is an automatic analyzer characterized in that it is a reagent used for analysis or a cleaning liquid used after analysis.
PCT/JP2021/007489 2020-09-29 2021-02-26 Automatic analysis device WO2022070460A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022553441A JP7397216B2 (en) 2020-09-29 2021-02-26 automatic analyzer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020-163380 2020-09-29
JP2020163380 2020-09-29

Publications (1)

Publication Number Publication Date
WO2022070460A1 true WO2022070460A1 (en) 2022-04-07

Family

ID=80950077

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2021/007489 WO2022070460A1 (en) 2020-09-29 2021-02-26 Automatic analysis device

Country Status (2)

Country Link
JP (1) JP7397216B2 (en)
WO (1) WO2022070460A1 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007303882A (en) * 2006-05-09 2007-11-22 Olympus Corp Autoanalyzer
JP2009168730A (en) * 2008-01-18 2009-07-30 Hitachi High-Technologies Corp Autoanalyzer
JP2013217741A (en) * 2012-04-06 2013-10-24 Hitachi High-Technologies Corp Automatic analyzer
JP2015114122A (en) * 2013-12-09 2015-06-22 株式会社東芝 Automatic analysis device
JP2018040621A (en) * 2016-09-06 2018-03-15 株式会社日立ハイテクノロジーズ Automatic analyzer
WO2020121726A1 (en) * 2018-12-11 2020-06-18 株式会社日立ハイテク Automated analyzer

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007303882A (en) * 2006-05-09 2007-11-22 Olympus Corp Autoanalyzer
JP2009168730A (en) * 2008-01-18 2009-07-30 Hitachi High-Technologies Corp Autoanalyzer
JP2013217741A (en) * 2012-04-06 2013-10-24 Hitachi High-Technologies Corp Automatic analyzer
JP2015114122A (en) * 2013-12-09 2015-06-22 株式会社東芝 Automatic analysis device
JP2018040621A (en) * 2016-09-06 2018-03-15 株式会社日立ハイテクノロジーズ Automatic analyzer
WO2020121726A1 (en) * 2018-12-11 2020-06-18 株式会社日立ハイテク Automated analyzer

Also Published As

Publication number Publication date
JPWO2022070460A1 (en) 2022-04-07
JP7397216B2 (en) 2023-12-12

Similar Documents

Publication Publication Date Title
US20190346470A1 (en) Automatic analyzer
JP4110101B2 (en) Automatic analyzer
US20140100139A1 (en) Method for scheduling samples in a combinational clinical analyzer
JP3873039B2 (en) Automatic analyzer
JPH10339732A (en) Automatic analytical device and its supporting system
JP2000146987A (en) Apparatus and method for autoanalysis
JP5898972B2 (en) Automatic analyzer
JP7075923B2 (en) Automatic analyzer
JP4582157B2 (en) Automatic analyzer and rack transport method
JP2009036723A (en) Automatic analysis apparatus and operation environment setting method
JP2006337386A (en) Automatic analyzer
JP5097466B2 (en) Automatic analyzer
EP4109105A1 (en) Automatic analysis device
JP2009020059A (en) Automatic analyzer and analysis method of the same
WO2022070460A1 (en) Automatic analysis device
JP6340245B2 (en) Automatic analyzer
JP2005274470A (en) Automatic analyzer
JP2011257427A (en) Automatic analyzer
JP7052051B2 (en) Automatic analyzer
JP4968368B2 (en) Automatic analyzer and rack transport method
JP7053898B2 (en) Automated analysis system and sample transport method
JP7459095B2 (en) Automatic analyzer and how to operate it
JP7010768B2 (en) Automatic analyzer and sample transfer method
CN113391078A (en) Automatic analysis device and analysis method
US20220018861A1 (en) Automatic analysis device

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 21874768

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2022553441

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 21874768

Country of ref document: EP

Kind code of ref document: A1