WO2022065579A1 - Système et procédé de transaction d'informations génétiques à base de chaîne de blocs - Google Patents

Système et procédé de transaction d'informations génétiques à base de chaîne de blocs Download PDF

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Publication number
WO2022065579A1
WO2022065579A1 PCT/KR2020/015441 KR2020015441W WO2022065579A1 WO 2022065579 A1 WO2022065579 A1 WO 2022065579A1 KR 2020015441 W KR2020015441 W KR 2020015441W WO 2022065579 A1 WO2022065579 A1 WO 2022065579A1
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WIPO (PCT)
Prior art keywords
genetic information
user
genetic
information
digital
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PCT/KR2020/015441
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English (en)
Korean (ko)
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이호준
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이호준
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/20—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B10/00—ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L9/00—Cryptographic mechanisms or cryptographic arrangements for secret or secure communications; Network security protocols
    • H04L9/06—Cryptographic mechanisms or cryptographic arrangements for secret or secure communications; Network security protocols the encryption apparatus using shift registers or memories for block-wise or stream coding, e.g. DES systems or RC4; Hash functions; Pseudorandom sequence generators
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L9/00—Cryptographic mechanisms or cryptographic arrangements for secret or secure communications; Network security protocols
    • H04L9/06—Cryptographic mechanisms or cryptographic arrangements for secret or secure communications; Network security protocols the encryption apparatus using shift registers or memories for block-wise or stream coding, e.g. DES systems or RC4; Hash functions; Pseudorandom sequence generators
    • H04L9/0643—Hash functions, e.g. MD5, SHA, HMAC or f9 MAC
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L9/00—Cryptographic mechanisms or cryptographic arrangements for secret or secure communications; Network security protocols
    • H04L9/50—Cryptographic mechanisms or cryptographic arrangements for secret or secure communications; Network security protocols using hash chains, e.g. blockchains or hash trees

Definitions

  • the present invention relates to a block chain-based genetic information transaction system and method thereof, and a block chain-based genetic information transaction system to apply individual genetic information to a block chain to eliminate the possibility of forgery or falsification and methods thereof.
  • Data traffic on the network has already increased semantically more data traffic between sensors and sensors and devices and devices than data traffic exchanged between people, and it is expected to increase exponentially in the future. Attempts are being made to collect such semantic data traffic as big data and use it as a target for machine learning.
  • An object of the present invention is to provide a genetic information transaction system and method based on a block chain in which individual genetic information is applied to a block chain to eliminate the possibility of forgery or falsification and transaction.
  • each user terminal connected to the genetic information value transaction system through a network
  • Creating and giving a digital ID for each user when receiving genetic information from the user, converting the provided genetic information into a form in which one header information and one sequence information are combined, and converting the datad genetic information into a block chain
  • the method may further include receiving a request for a genetic test from the user through the user terminal, and requesting a genetic test for the user from a genetic testing company.
  • the genetic information is obtained through a next generation sequencing (NGS) method, and the step of dataizing the genetic information is analyzing the obtained gene information through Whole Genome Sequencing (WGS) technology. can be converted into data.
  • NGS next generation sequencing
  • WGS Whole Genome Sequencing
  • the step of matching and storing the digital ID of the user includes the steps of generating a hash value by encrypting the data-generated genetic information data, and generating a private key corresponding to the hash value to match the digital ID of the user It may include a step of storing.
  • the step of providing the reward value includes receiving a request for at least one piece of genetic information from among a plurality of pre-stored genetic information from a third party, and providing the requested genetic information to the third party while hiding the matched digital ID
  • the method may further include: determining a reward value according to the provision of the genetic information, and providing the determined reward value to the user who has provided the genetic information.
  • the value of the reward may be differentially determined according to a ratio of the number of times of providing the gene information used by a third party or the number of times of providing the total genetic information to the number of times of providing the genetic information.
  • a digital ID for each user is a user terminal connected to the genetic information value transaction system through a network
  • a DID generating unit that generates and gives gene information
  • a data conversion unit that changes the provided genetic information into a form in which one header information and one sequence information are combined when receiving genetic information from the user, and converts the datad genetic information into a block chain a storage unit that matches and stores the user's digital ID on the screen
  • a control unit that provides a reward value to the user corresponding to the digital ID that provided the corresponding genetic information when the genetic information is provided at the request of a third party
  • the probability of forgery or falsification of genes can be reduced, and profits can be provided according to the ratio of the genes used to facilitate active transactions.
  • FIG. 1 is a view for explaining a genetic information transaction system according to an embodiment of the present invention.
  • FIG. 2 is a diagram for explaining the configuration of a genetic information transaction system according to an embodiment of the present invention.
  • FIG. 3 is a flowchart for explaining a genetic information transaction method according to an embodiment of the present invention.
  • FIG. 4 is an exemplary diagram for explaining dataized genetic information according to an embodiment of the present invention.
  • FIG. 5 is a diagram for explaining step S340 of FIG. 3 .
  • FIG. 6 is an exemplary view illustrating a genetic information transaction method according to an embodiment of the present invention.
  • FIGS. 1 and 2 a genetic information transaction system according to an embodiment of the present invention will be described with reference to FIGS. 1 and 2 .
  • FIG. 1 is a diagram for explaining a genetic information trading system according to an embodiment of the present invention
  • FIG. 2 is a diagram for explaining the configuration of a genetic information trading system according to an embodiment of the present invention.
  • the genetic information transaction system 100 is connected to the user terminal 200 through a network.
  • the genetic information transaction system 100 stores the genetic information of a plurality of users based on the block chain, provides the stored genetic information to a third party, and a reward value according to the provided result is provided to the user corresponding to the genetic information.
  • the user terminal 200 accesses the genetic information transaction system 100 to register genetic information, and receives a reward value according to a result provided to a third party.
  • the user terminal 200 is a portable participant terminal, and may be implemented as a device capable of exchanging information by connecting to a network by wire or wireless, such as a notebook computer, a smart pad, or a smart phone.
  • the genetic information transaction system 100 includes a DID generating unit 110 , a communication unit 120 , a data conversion unit 130 , a storage unit 140 , and a control unit 150 .
  • a DID generating unit 110 includes a communication unit 120 , a communication unit 120 , a data conversion unit 130 , a storage unit 140 , and a control unit 150 .
  • the DID generating unit 110 generates and provides a digital ID for each user to the user terminal 200 connected to the genetic information value system 100 through a network.
  • the communication unit 120 receives a request for a genetic test from the user through the user terminal 200 , and requests a genetic test for the user from a genetic test company.
  • the data conversion unit 130 receives the genetic information from the user and converts the genetic information into data.
  • the storage unit 140 matches and stores the data-generated genetic information with the digital ID of the user on the block chain.
  • the controller 150 when genetic information is provided at the request of a third party, the controller 150 provides a reward value to the user corresponding to the digital ID providing the corresponding genetic information.
  • controller 150 may generate a hash value by encrypting the data-generated genetic information data, generate a private key corresponding to the hash value, and store it by matching with the digital ID of the corresponding user.
  • control unit 150 when receiving a request for at least one gene information from among a plurality of pre-stored genetic information from a third party, the control unit 150 provides the requested gene information to a third party while hiding the matched digital ID, and the genetic information determines the reward value according to the provision of , and provides the set reward value to the user who provided genetic information.
  • the value of the reward value is differentially determined according to the ratio of the number of times of providing the genetic information used by a third party or the number of times of providing the total genetic information to the number of times of providing the genetic information.
  • FIG. 3 is a flowchart for explaining a genetic information transaction method according to an embodiment of the present invention.
  • the DID generating unit 110 generates and provides a digital ID for each user to the user terminal 200 connected to the genetic information value transaction system 100 through a network (S310).
  • the digital ID is unique identification information corresponding to each of the plurality of user terminals 200, and is generated using a block chain.
  • the communication unit 120 requests a genetic test for the user from the genetic test company ( S320 ).
  • the genetic testing company collects samples necessary for genetic testing, such as the hair, epidermis or skin of the user who requested the genetic test.
  • the genetic testing company extracts the gene from the collected sample through the next generation sequencing (NGS) method.
  • NGS next generation sequencing
  • next-generation sequencing (NGS) method is used to rapidly decipher genome information by decomposing one genome into a plurality of pieces and recombination of the data of the plurality of decomposed pieces using bioinformatics techniques, In an embodiment of the present invention, it is used to extract genetic information of a user who has requested a genetic test.
  • the genetic information is composed of a plurality of adenine (A), guanine (G), cytosine (C) and thymine (T) arrangement.
  • the data conversion unit 130 receives the genetic information from the user and converts the genetic information into data (S330).
  • the data conversion unit 130 analyzes the acquired genetic information through a whole genome sequencing (WGS) technology and converts it into data.
  • WGS whole genome sequencing
  • the full-length genome analysis (WGS) technology is a method of analyzing and researching associations between various genetic variants and specific traits that appear in a plurality of individuals existing within a group of a specific biological species, and the present invention In the embodiment, it is used to analyze and dataize human genetic information.
  • the DNA SEQUENCING data DID may include Whole Genome Sequencing (WGS) data DID (Digital ID).
  • WGS Whole Genome Sequencing
  • FIG. 4 is an exemplary diagram for explaining dataized genetic information according to an embodiment of the present invention.
  • the data-coded gene information is formed by combining one header information and one sequence information.
  • sequence information corresponds to each user's genetic information.
  • the storage unit 140 matches and stores the data generated genetic information with the digital ID of the user on the block chain (S340).
  • the storage unit 140 generates a hash value by encrypting the data-generated genetic information data.
  • the storage unit 140 generates a private key corresponding to the hash value, matches the user's digital ID and stores the generated key.
  • the hash value is encrypted data of genetic information data
  • the private key means a key capable of decoding the hash value
  • the storage unit 140 matches the hash value with the digital ID of the user on the block chain and stores it.
  • the block chain is a distributed data storage technology that duplicates and stores blocks containing the same data in a plurality of computers or terminals connected through a network.
  • the user's digital ID corresponding to the hash value of the genetic information data is used to store
  • FIG. 5 is a diagram for explaining step S340 of FIG. 3 .
  • control unit 150 determines that access is authorized and the corresponding genetic data provides
  • control unit 150 determines that there is no access right and does not provide the corresponding genetic data .
  • the controller 150 provides a reward value to the user corresponding to the digital ID that has provided the corresponding genetic information (S350).
  • the controller 150 when receiving a request for at least one piece of genetic information from among a plurality of pre-stored genetic information from a third party, the controller 150 provides the requested genetic information to the third party while hiding the matched digital ID.
  • the controller 150 provides the digital ID corresponding to the genetic information to the third party in a hidden state in order to protect the user information corresponding to the genetic information requested from the third party.
  • the controller 150 determines the reward value of the genetic information provided to the third party.
  • the value of the reward provided to the user who provided the genetic information differs according to the ratio of the number of times of providing the gene information used by a third party or the number of times of providing the corresponding genetic information to the number of times of providing the total genetic information. is decided
  • control unit 150 sets the reward value of user B greater than that of user A. set to
  • the controller 150 provides the set reward value to the user who has provided the genetic information.
  • the reward value may be provided in points, mileage or cash, and the number of times of providing genetic information and the reward value are stored in each block of the block chain.
  • FIG. 6 is an exemplary view illustrating a genetic information transaction method according to an embodiment of the present invention.
  • the genetic information transaction system 100 encrypts data on genetic information input from a user and stores it in a block chain, and provides a private key to the user.
  • the genetic information transaction system 100 stores the encoded genetic information and the private key together in the block chain.
  • the encoded genetic information for each user is stored separately in the block chain.
  • the genetic information transaction system 100 decrypts the encoded genetic information and provides it to a third party, and sets a price according to the amount of the provided genetic information.
  • the genetic information transaction system 100 upon receiving a price set by a third party, the genetic information transaction system 100 gives a reward value to the provider of the provided genetic information.

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Abstract

Selon la présente invention, un procédé de transaction de valeur d'informations génétiques utilisant un système de transaction d'informations génétiques à base de chaîne de blocs comprend les étapes consistant : à générer un ID numérique pour chaque utilisateur à l'aide d'un terminal utilisateur connecté à un système de transaction de valeur d'informations génétiques par l'intermédiaire d'un réseau et à attribuer l'ID numérique ; à recevoir des informations génétiques de l'utilisateur et à convertir les informations génétiques en données ; à mettre en correspondance les informations génétiques converties en données avec un ID numérique de l'utilisateur et à stocker les informations génétiques sur une chaîne de blocs ; et lorsque les informations génétiques sont fournies à la demande d'un tiers, à fournir une valeur de récompense à l'utilisateur correspondant à l'ID numérique par l'intermédiaire duquel les informations génétiques sont fournies.
PCT/KR2020/015441 2020-09-22 2020-11-06 Système et procédé de transaction d'informations génétiques à base de chaîne de blocs WO2022065579A1 (fr)

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KR1020200122369A KR20220039349A (ko) 2020-09-22 2020-09-22 블록체인을 기반으로 하는 유전자 정보 거래 시스템 및 그 방법

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Cited By (1)

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CN117527191A (zh) * 2024-01-05 2024-02-06 北京泰尔英福科技有限公司 一种基于区块链数字身份蜂窝模组的数据校验方法及系统

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KR102535319B1 (ko) * 2022-09-02 2023-05-26 주식회사 메디클라우드 블록체인 기반 유전자 정보 거래 서비스 제공 방법, 장치 및 시스템

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KR102109885B1 (ko) * 2019-08-02 2020-05-12 주식회사 클리노믹스 블록체인 기반의 건강 데이터 관리 시스템 및 그 구동방법

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KR101893729B1 (ko) * 2018-03-28 2018-10-04 주식회사 마크로젠 복수의 블록체인에 기반한 데이터 공유 방법
KR101946557B1 (ko) * 2018-05-15 2019-05-03 한국마필거래소(주) 블록체인을 이용하여 유전자 정보를 저장하고 관리하는 방법 및 시스템
KR101946555B1 (ko) * 2018-05-15 2019-05-03 한국마필거래소(주) 블록체인 기반의 유전자 정보 유통 방법 및 시스템
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117527191A (zh) * 2024-01-05 2024-02-06 北京泰尔英福科技有限公司 一种基于区块链数字身份蜂窝模组的数据校验方法及系统
CN117527191B (zh) * 2024-01-05 2024-03-22 北京泰尔英福科技有限公司 一种基于区块链数字身份蜂窝模组的数据校验方法及系统

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