WO2022002279A1 - 电解脱弹簧圈推送杆端部结构及其解脱系统、栓塞系统 - Google Patents

电解脱弹簧圈推送杆端部结构及其解脱系统、栓塞系统 Download PDF

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Publication number
WO2022002279A1
WO2022002279A1 PCT/CN2021/110686 CN2021110686W WO2022002279A1 WO 2022002279 A1 WO2022002279 A1 WO 2022002279A1 CN 2021110686 W CN2021110686 W CN 2021110686W WO 2022002279 A1 WO2022002279 A1 WO 2022002279A1
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WIPO (PCT)
Prior art keywords
conductive tube
metal wire
tube
push rod
spring coil
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PCT/CN2021/110686
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English (en)
French (fr)
Inventor
邓舒浩
陈冰
郭远益
潘光亮
张朔
Original Assignee
微创神通医疗科技（上海）有限公司
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Application filed by 微创神通医疗科技（上海）有限公司 filed Critical 微创神通医疗科技（上海）有限公司
Priority to JP2022581407A priority Critical patent/JP2023534915A/ja
Priority to EP21833016.5A priority patent/EP4151163A4/en
Priority to US18/014,039 priority patent/US20230277188A1/en
Publication of WO2022002279A1 publication Critical patent/WO2022002279A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00526—Methods of manufacturing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00902—Material properties transparent or translucent
    • A61B2017/00915—Material properties transparent or translucent for radioactive radiation
    • A61B2017/0092—Material properties transparent or translucent for radioactive radiation for X-rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00929—Material properties isolating electrical current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12063—Details concerning the detachment of the occluding device from the introduction device electrolytically detachable

Definitions

  • the invention relates to the field of medical instruments, in particular to an end structure of a push rod for an electrolytic release spring coil, a release system and an embolization system.
  • intracranial aneurysm In recent years, the incidence of intracranial aneurysm has gradually increased, becoming a common disease, and the disease has a high mortality and disability rate, which should not be underestimated.
  • the risk of aneurysm rupture during surgery is higher, while endovascular interventional therapy is less invasive and less risky.
  • the advantages of less complications, etc. have attracted more and more people's attention and attention.
  • Interventional treatment of aneurysm mainly adopts coil embolization technology.
  • the implanted coil needs to be pushed by the delivery system (push rod).
  • the delivery system push rod
  • the traditional aneurysm interventional treatment product Guglielmi Detachable Coil adopts the electrolytic detachment method.
  • the positive electrode of the end structure of the electrolytic detachment coil push rod is connected to the exposed metal area of the coil delivery guide wire, and then the negative electrode is connected to the steel needle and inserted into the patient's skin.
  • the structure at the end of the push rod of the electrolytic release spring coil is powered, and a loop is formed through the human body, so that the exposed metal area of the positive electrode conveying guide wire is dissolved to complete the release.
  • this electrolysis method is stable and reliable, the operation steps are complicated, the release time is long, and the hypodermic needle insertion will bring additional trauma and pain to the patient.
  • the purpose of the present invention is to provide an end structure of the push rod of the electrolytic release spring coil and its release system and embolization system.
  • the present invention can avoid the need of inserting a needle into the patient's body for the traditional electrolytic decoupling coil structure, reduce the pain caused by inserting the needle to the patient, and simplify the operation mode of the doctor.
  • An electrolytic release spring coil push rod end structure comprising at least one metal wire, at least one first conductive tube, at least one insulating portion and at least one second conductive tube;
  • the at least one insulating part is respectively connected with the first conductive tube and the second conductive tube, and is used to electrically insulate the first conductive tube and the second conductive tube, and the first conductive tube and the second conductive tube are electrically insulated.
  • the second conductive tube is assembled coaxially;
  • One end of the at least one metal wire is electrically connected to the at least one second conductive tube.
  • At least one limiting structure is also included, and one end of the at least one metal wire is connected to the at least one limiting structure.
  • it also includes at least one fixing structure formed at the end of the second conductive tube, and the at least one fixing structure is connected with the at least one metal wire.
  • the wire has a proximal section, a distal section and an intermediate section, and the intermediate section is located between the proximal section and the distal section.
  • the material of the metal wire is selected from one or more of gold, silver, copper, platinum, and stainless steel.
  • the diameter of the metal wire ranges from 0.04 to 0.08 mm, and the length of the metal wire ranges from 1600 to 2400 mm.
  • the proximal section of the metal wire is located in the lumen of the second conductive tube
  • the middle section of the metal wire is located in the lumen of the first conductive tube
  • the distal section of the metal wire is located in the lumen of the tube. extraluminal.
  • the proximal section of the metal wire is a first bare metal wire that is not coated with an insulating coating, the first bare metal wire is in contact with the limiting structure and the fixing structure respectively, and the first bare metal wire is in contact with the limiting structure and the fixing structure respectively.
  • the length of the wire ranges from 10 to 50 mm.
  • the middle section of the metal wire is coated with an insulating coating, and the length of the middle section of the metal wire ranges from 1550 mm to 2200 mm.
  • the length of the distal segment of the metal wire ranges from 50 to 200 mm.
  • the distal section of the metal wire has a second bare metal wire that is not coated with an insulating coating, and the second bare metal wire constitutes a release structure for forming a release loop with the first conductive tube through a dielectric solution environment,
  • the length of the release structure ranges from 0.01 to 0.08 mm.
  • both the first conductive tube and the second conductive tube are made of metal tubes.
  • the outer diameter of the first conductive tube and the second conductive tube ranges from 0.30 to 0.45 mm, and the inner diameter ranges from 0.15 to 0.35 mm.
  • the length of the first conductive tube ranges from 1400 to 2000 mm, and the length of the second conductive tube ranges from 200 to 400 mm.
  • the first conductive tube and the second conductive tube are directly connected, and the insulating portion is provided at the connection between the first conductive tube and the second conductive tube.
  • the first conductive tube and the second conductive tube are embedded with each other.
  • the embedding enables the end of the first conductive tube or the second conductive tube to have at least one embedded end, and the length of the at least one embedded end ranges from 10 to 40 mm.
  • the insulating part adopts insulating heat shrinkable tube or insulating material.
  • one end of the insulating heat-shrinkable tube is sleeved on the outer ring of one end of the first conductive tube, and the other end of the insulating heat-shrinkable tube extends into the inner ring of one end of the second conductive tube; or the insulating heat-shrinkable tube
  • One end of the insulating heat shrinkable tube is sleeved on the outer ring of one end of the second conductive tube, and the other end of the insulating heat shrinkable tube extends into the inner ring of one end of the first conductive tube.
  • the insulating material is sprayed on the connection between the first conductive tube and the second conductive tube.
  • the material of the insulating material is selected from any one of polyimide coating, alumina ceramic coating, ceramic polymer coating, polybenzimidazole coating, and polytetrafluoroethylene coating.
  • the first conductive tube and the second conductive tube are indirectly connected through the insulating portion.
  • the insulating part uses a sheath to connect the first conductive tube and the second conductive tube.
  • the sheath covers the outer ring of the connection between the first conductive tube and the second conductive tube, and the connection between the first conductive tube and the second conductive tube is butted or overlapped with each other.
  • the length of the covering is in the range of 20-60 mm, and the thickness of the covering is 0.05-0.1 mm.
  • the insulating part uses a sleeve to connect the first conductive tube and the second conductive tube.
  • the length of the sleeve is in the range of 20-60 mm, and the thickness of the sleeve is in the range of 0.1-0.15 mm.
  • the insulating part adopts a socket structure or a nut structure to connect the first conductive tube and the second conductive tube.
  • the at least one limiting structure adopts any one of a ring, a cylinder, a square column or a cylinder with a hole, a square column with a hole and a sphere with a hole, and/or, the material of the limiting structure (5) is selected.
  • the at least one limiting structure is located inside the second conductive tube; the at least one limiting structure is coplanar and flush with the end face of the second conductive tube; the at least one limiting structure is located in the second conductive tube. beyond the end of the second conductive tube.
  • the distance between the at least one limiting structure located outside the end of the second conductive tube and the end of the second conductive tube ranges from 0 to 2 mm.
  • the at least one limiting structure and the second conductive tube are connected by gluing, welding or plugging.
  • one end of the fixing structure extends into the lumen of the second conductive tube and covers the limiting structure and one end of the metal wire.
  • the fixing structure is selected from conductive adhesive materials.
  • the conductive adhesive material forms a hemisphere or an ellipsoid after curing.
  • the radius size of the hemisphere ranges from 0.3 to 0.45 mm.
  • the distance from the top of the ellipsoid to the end of the second conductive tube ranges from 0.15 to 0.65 mm.
  • the stripping system further includes a stripper, and the stripper includes a positive pole of the power supply and a negative pole of the power supply;
  • the negative electrode of the power supply and the first conductive tube form a negative circuit
  • the positive electrode of the power supply, the second conductive tube and the metal wire form a positive circuit
  • the distal section of the metal wire includes a release structure.
  • the release structure of the metal wire and the first conductive tube are simultaneously in the dielectric solution environment, the negative circuit and the positive circuit are connected to form a release loop.
  • the decoupler provides direct current or alternating current.
  • the stripping system further includes a stripper, and the stripper includes a positive pole of the power supply and a negative pole of the power supply;
  • the positive electrode of the power supply and the first conductive tube form a positive circuit
  • the negative electrode of the power supply, the second conductive tube and the metal wire form a negative circuit
  • the distal section of the metal wire includes a release structure.
  • the release structure of the metal wire and the first conductive tube are simultaneously in the dielectric solution environment, the negative circuit and the positive circuit are connected to form a release loop.
  • the decoupler provides direct current or alternating current.
  • a plugging system with the above-mentioned spring coil pushing rod end structure the plugging system further comprises a metal spring coil or a degradable spring coil.
  • the metal coil or the degradable coil has a 2D primary structure or a 3D secondary structure.
  • the material of the degradable spring coil is selected from any one of polymer coating, hydrophilic coating or biologically active material coating.
  • the degradable spring coil includes at least one first coil and at least one second coil.
  • the at least one first coil and the at least one second coil are coaxially arranged, and the at least one second coil is placed in the inner cavity of the at least one first coil.
  • the material of the at least one first coil is a polymer material, such as polylactic acid, polyglycolic acid, lactic acid-glycolic acid copolymer, polydioxanone, polycaprolactone, polyurethane, shell Either polysaccharide or hyaluronic acid.
  • a polymer material such as polylactic acid, polyglycolic acid, lactic acid-glycolic acid copolymer, polydioxanone, polycaprolactone, polyurethane, shell Either polysaccharide or hyaluronic acid.
  • the material of the at least one first coil is selected from a metal material, and the metal material is any one of magnesium and its alloys, and iron and its alloys.
  • the at least one second coil is a radiopaque coil.
  • the length of the at least one second coil is not greater than the length of the at least one first coil.
  • An insulating part is provided between the first conductive tube and the second conductive tube for separation, so as to effectively avoid the risk of short circuit, and the first conductive tube and the second conductive tube are provided with embedded connection, sheath connection, sleeve connection, socket Various connection methods such as the first conductive tube and the second conductive tube form a coaxial one-piece structure, which can be inserted into the electrolysis device together to form a release loop to complete the release.
  • the metal wire can hook the second conductive tube of the push rod, so that it is connected to the second conductive tube, and a conductive fixing structure is arranged on the second conductive tube, which can not only remove the metal
  • the wire is fixed to avoid its displacement, and the contact area between the wire and the second conductive tube can be increased to avoid the risk of open circuit.
  • the first conductive tube and the second conductive tube are coaxially assembled into an integrated structure, which can be inserted into the electrolysis device to form a circuit, which simplifies the operation steps of the doctor, shortens the release time of the coil, and improves the operation efficiency. , which avoids the need to insert needles into the patient's body in traditional electrolysis, and reduces the trauma and pain of the patient.
  • FIG. 1 shows a schematic diagram of the structure of the end of an electrolytic release spring coil push rod according to an embodiment of the present invention.
  • FIG. 2A shows a schematic diagram of the structure of the negative electrode embedded in the positive electrode in the end structure of the push rod end structure of an electrolytic release spring coil according to an embodiment of the present invention.
  • FIG. 2B shows a schematic diagram of the structure of the positive electrode embedded in the negative electrode in the end structure of the push rod of an electrolytic release spring coil according to an embodiment of the present invention.
  • FIG. 3A shows a schematic structural diagram of a butt-and-sleeve type of assembly between the positive electrode and the negative electrode in an end structure of an electrolytic release spring coil push rod according to an embodiment of the present invention.
  • FIG. 3B shows a schematic structural diagram of the assembling manner between the positive electrode and the negative electrode in an end structure of an electrolytic release spring coil push rod according to an embodiment of the present invention in a lap wrapping type.
  • FIG. 4 shows a schematic structural diagram of a sleeve type assembling manner between the positive electrode and the negative electrode in the end structure of the push rod of an electrolytic release spring coil according to an embodiment of the present invention.
  • 5A shows a schematic structural diagram of a socket-type assembly between the positive electrode and the negative electrode in the end structure of the push rod of an electrolytic release spring coil according to an embodiment of the present invention, and the positive electrode is inserted into the negative electrode.
  • 5B shows a schematic structural diagram of a socket-type assembly between the positive electrode and the negative electrode in the end structure of the push rod of an electrolytic release spring coil according to an embodiment of the present invention, and the negative electrode is inserted into the positive electrode.
  • FIG. 6A shows a schematic diagram of a structure in which the positive electrode and the negative electrode are assembled in a nut type, the positive electrode is an external thread, and the negative electrode is an internal thread in an electrolytic release spring coil push rod end structure according to an embodiment of the present invention.
  • FIG. 6B shows a schematic diagram of the structure in which the positive electrode and the negative electrode are assembled in a nut type, the positive electrode is an internal thread, and the negative electrode is an external thread in an electrolytic release spring coil push rod end structure according to an embodiment of the present invention.
  • FIG. 7A shows a schematic structural diagram of an insulating heat-shrinkable tube sleeved on the outside of a negative electrode in an end structure of an electrolytic release spring coil push rod according to an embodiment of the present invention.
  • FIG. 7B shows a schematic structural diagram of an insulating heat-shrinkable tube sleeved on the outside of the positive electrode in an end structure of an electrolytic release spring coil push rod according to an embodiment of the present invention.
  • FIG. 8A shows a schematic structural diagram of the insulating coating applied to the negative electrode in the end structure of the push rod of an electrolytic release spring coil according to an embodiment of the present invention.
  • FIG. 8B shows a schematic structural diagram of the insulating coating applied to the positive electrode in the end structure of the push rod of an electrolytic release spring coil according to an embodiment of the present invention.
  • FIG. 9 is a schematic diagram of gluing or welding the limiting structure and the positive electrode in the end structure of the push rod of an electrolytic release spring coil according to an embodiment of the present invention.
  • FIG. 10 is a schematic diagram showing the connection between the limiting structure and the positive electrode through a plug in the end structure of the push rod of an electrolytic release spring coil according to an embodiment of the present invention.
  • FIG. 11 is a schematic structural diagram of a hemispherical fixed structure in an end structure of an electrolytically decoupled spring coil push rod according to an embodiment of the present invention.
  • FIG. 12A is a schematic structural diagram of a large-area ellipsoid in the end structure of a push rod end structure of an electrolytic release spring coil according to an embodiment of the present invention.
  • FIG. 12B is a schematic structural diagram of a small-area ellipsoid in the end structure of an electrolytic release spring coil push rod end structure according to an embodiment of the present invention.
  • proximal and distal are the relative orientation, relative position, orientation of elements or actions relative to each other from the perspective of the physician using the product, although “proximal” and “distal” are not is restrictive, but “proximal” generally refers to the end of the product that is closest to the physician during normal operation, while “distal” generally refers to the end that first enters the patient.
  • FIG. 1 it is a schematic diagram of the end structure of the push rod of the electrolytic release spring coil according to an embodiment of the present invention.
  • An insulating portion 3 and at least one second conducting tube 4, the at least one insulating portion 3 is respectively connected with the first conducting tube 2 and the second conducting tube 4, and is used for connecting the first conducting tube 2 and the second conducting tube 4.
  • the second conductive tube 4 is insulated; and one end of the at least one metal wire 1 is electrically connected to the at least one second conductive tube 4 .
  • the first conductive tube 2 is a negative electrode
  • the second conductive tube 4 is a positive electrode
  • one end of the metal wire 1 penetrates into the hollow lumen and is hooked on the limiting structure 5 .
  • the end is also formed with a fixing structure 6 , the fixing structure 6 firmly connects the metal wire 1 and the second conductive tube 4 to avoid the problem of poor contact and ensure that the second conductive tube 4 and the metal wire 1 are energized.
  • the first conductive tube 2, the second conductive tube 4, the metal wire 1, and the insulating part 3 are assembled together into an integrated structure and inserted into the release device to energize to form a loop, which is convenient, fast and effective to complete the release.
  • the first conductive tube 2 may be a positive electrode
  • the second conductive tube 4 may be a negative electrode.
  • the metal wire 1 is selected from a metal wire material with good electrical conductivity.
  • the metal wire 1 is made of stainless steel.
  • the metal wire material includes but is not limited to one of gold, silver, copper, platinum, and stainless steel. or more.
  • the metal wire 1 in the end structure of the push rod of the electrolytic release spring coil according to an embodiment of the present invention is divided into three sections as a whole and located at three positions respectively.
  • the metal wire 1 has a proximal section and a distal section. and a middle section, the middle section is located between the proximal section and the distal section.
  • the proximal section of the metal wire 1 is located in the lumen of the second conductive tube 4, the middle section of the metal wire 1 is located in the lumen of the first conductive tube 2, and the distal section of the metal wire 1 is located outside the lumen of the tube , the present invention does not limit the three positions of the three segments of the metal wire 1, as long as the second conductive tube 4 can be energized.
  • the proximal part of the metal wire 1 is the first bare metal wire without insulating coating, the first bare metal wire is in contact with the limiting structure 5 and the fixing structure 6 respectively, and the length of the first bare metal wire ranges from 0.1 to 1 mm.
  • the length of the first exposed metal wire ranges from 0.3 to 0.5 mm.
  • the middle section of the metal wire 1 is coated with an insulating coating, and the length of the middle section of the metal wire 1 ranges from 1550 to 2200 mm.
  • the length of the distal section of the metal wire 1 ranges from 10 to 30 mm.
  • the length of the middle section of the metal wire 1 ranges from 1800 to 1900 mm, and the length of the distal section of the metal wire 1 ranges from 15 to 25 mm.
  • the distal section of the metal wire 1 has a second bare metal wire that is not coated with an insulating coating, and the second bare metal wire constitutes a release structure 7 for forming a release loop with the first conductive tube 2 through a dielectric solution environment (eg, a body fluid environment) , the length of the release structure 7 ranges from 0.01 to 0.08 mm.
  • the length of the release structure 7 in the first embodiment is preferably 0.025-0.06 mm.
  • the diameter of the metal wire 1 ranges from 0.04 to 0.08 mm, and the length of the metal wire 1 ranges from 1600 to 2400 mm.
  • the diameter range of the metal wire 1 is preferably 0.04-0.06 mm, and the length of the metal wire 1 is preferably 1800-1900 mm.
  • the first conductive tube 2 and the second conductive tube 4 can be directly connected as shown in FIG. 1 , FIG. 2A or FIG. 2B , and the insulating part 3 is arranged at the connection of the first conductive tube 2 and the second conductive tube 4 .
  • the direct connection mode of the first conductive tube 2 and the second conductive tube 4 is mutual embedding, and the above-mentioned embedding mode makes the first conductive tube 2 or the second conductive tube 4
  • the end portion has at least one embedded end 8 , the length of the embedded end 8 ranges from 10 to 40 mm, and the diameter of the tail of the embedded end 8 gradually decreases toward the head of the embedded end 8 . As shown in FIG.
  • the embedded end 8 may be arranged on the first conductive tube 2 , and the embedded end 8 on the first conductive tube 2 is embedded with the second conductive tube 4 . As shown in FIG. 2B , the embedded end 8 may also be disposed on the second conductive tube 4 , and embedded with the first conductive tube 2 through the embedded end 8 on the second conductive tube 4 .
  • the first embodiment adopts the embedding method shown in FIG. 2A .
  • the length of the embedded end 8 is preferably 15-20 mm.
  • the embedded end 8 may be obtained by grinding the extended section of the first conductive tube 2 or the second conductive tube 4 .
  • the insulating portion 3 adopts an insulating heat-shrinkable tube 301 or an insulating material 302 .
  • the insulating portion 3 is used to connect the first conductive tube 2 and the second conductive tube 4, and the purpose is to electrically insulate the first conductive tube 2 and the second conductive tube 4 to prevent the occurrence of a short circuit.
  • the insulating heat shrinkable tube 301 is a PET heat shrink tube.
  • the insulating material 302 when used, the insulating material 302 is sprayed on the connection between the first conductive tube 2 and the second conductive tube 4 .
  • the material of the insulating material 302 is selected from any one of polyimide coating, alumina ceramic coating, ceramic polymer coating, polybenzimidazole coating, and polytetrafluoroethylene coating.
  • the first conductive tube 2 and the second conductive tube 4 may also be indirectly connected through the insulating part 3 .
  • the insulating part 3 uses a sheath 9 to connect the first conductive tube 2 and the second conductive tube 4, wherein the sheath 9 covers the connection between the first conductive tube 2 and the second conductive tube 4.
  • the joints of the first conductive tube 2 and the second conductive tube 4 are butted with each other.
  • the joints of the first conductive tube 2 and the second conductive tube 4 are overlapped with each other.
  • the length of the covering 9 ranges from 5 to 30 mm, and the thickness of the covering 9 ranges from 0.005 to 0.1 mm.
  • the insulating part 3 adopts a sleeve 10 to indirectly connect the first conductive tube 2 and the second conductive tube 4 , and both ends of the sleeve 10 are respectively sleeved into the Describe the inner circles of the first conductive tube 2 and the second conductive tube 4.
  • the length of the sleeve 10 ranges from 5 to 30 mm, and the thickness of the sleeve 10 ranges from 0.1 to 0.15 mm.
  • the insulating portion 3 adopts a socket structure to connect the first conductive tube 2 and the second conductive tube 4.
  • the end of the first conductive tube 2 has a plug structure
  • the end of the second conductive tube 4 has a socket structure or as shown in FIG. 5B
  • the end of the first conductive tube 2 has a socket structure
  • the end of the second conductive tube 4 has a plug structure.
  • the insulating portion 3 adopts a nut structure to connect the first conductive tube 2 and the second conductive tube 4.
  • the end of the first conductive tube 2 has an external thread
  • the end of the second conductive pipe 4 has internal threads or as shown in FIG. 6B
  • the end of the first conductive pipe 2 has internal threads
  • the end of the second conductive pipe 4 has external threads.
  • the first conductive tube 2 and the second conductive tube 4 are both made of metal tubes.
  • the outer diameter of the first conductive tube 2 and the second conductive tube 4 ranges from 0.30 to 0.45 mm, and the inner diameter ranges from 0.15 to 0.35 mm.
  • the length of the first conductive tube 2 ranges from 1400 to 2000 mm, and the length of the second conductive tube 4 ranges from 200 to 400 mm.
  • the purpose of setting the limiting structure 5 is to hook the first bare metal wire in the proximal section of the metal wire 1 to the second conductive tube 4 and realize electrical connection with the second conductive tube 4 .
  • the limiting structure 5 adopts any one of a ring, a cylinder, a square column or a cylinder with a hole, a square column with a hole and a sphere with a hole, and its materials include but are not limited to gold, silver, copper, platinum, platinum-tungsten, platinum-iridium Wait.
  • the limiting structure 5 adopts a circular ring.
  • the installation position of the limiting structure 5 in the second conductive tube 4 has the following installation positions:
  • the first installation location :
  • the limiting structure 5 is located inside the second conductive tube 4 .
  • the second installation location is the first installation location:
  • the limiting structure 5 is coplanar and flush with the end surface of the second conducting tube 4 , and the second installation position is selected in this embodiment.
  • the third installation location is the third installation location:
  • the limiting structure 5 is located outside the end of the second conductive tube 4 .
  • the distance between the limiting structure 5 located outside the end of the second conductive pipe 4 and the end of the second conductive pipe 4 ranges from 0 to 2 mm.
  • the distance between the limiting structure 5 and the end of the second conductive tube 4 ranges from 0.1 to 0.5 mm.
  • connection method between the limiting structure 5 and the second conductive tube 4 includes but is not limited to gluing, welding or plug connection.
  • the limiting structure 5 and the second conductive tube 4 are connected by welding.
  • one end of the fixing structure 6 extends into the lumen of the second conductive tube 4 and covers the limiting structure 5 and one end of the metal wire 1 .
  • the fixing structure 6 is selected from conductive adhesive materials.
  • a conductive adhesive material adopts conductive glue.
  • the conductive glue forms a hemisphere or an ellipsoid after curing.
  • the conductive glue in this embodiment is an ellipsoid after curing.
  • the radius size of the hemisphere ranges from 0.29 to 0.32 mm. As shown in FIGS.
  • the distance from the top of the ellipsoid to the end of the second conductive tube 4 ranges from 0.15 to 0.65 mm.
  • the preferred distance from the top of the ellipsoid to the end of the second conductive tube 4 is 0.15 mm. ⁇ 0.25mm.
  • Yet another embodiment of the present invention provides a release system with the end structure of the spring coil pushing rod, the release system further includes a release device, the release device provides a direct current or an alternating current, and the release device includes Positive power supply and negative power supply;
  • the negative electrode of the power supply and the first conductive tube form a negative circuit
  • the positive electrode of the power supply, the second conductive tube and the metal wire form a positive circuit
  • the distal section of the metal wire includes a release structure.
  • the release structure of the metal wire and the first conductive tube are simultaneously in the dielectric solution environment, the negative circuit and the positive circuit are connected to form a release loop.
  • Yet another embodiment of the present invention provides a release system with the end structure of the spring coil pushing rod, the release system further includes a release device, the release device provides a direct current or an alternating current, and the release device includes Positive power supply and negative power supply;
  • the positive electrode of the power supply and the first conductive tube form a positive circuit
  • the negative electrode of the power supply, the second conductive tube and the metal wire form a negative circuit
  • the distal section of the metal wire includes a release structure.
  • the release structure of the metal wire and the first conductive tube are simultaneously in the dielectric solution environment, the negative circuit and the positive circuit are connected to form a release loop.
  • Yet another embodiment of the present invention provides an embolization system, which includes a push rod with the above-mentioned end structure and a spring coil, and the spring coil is a metal coil or a degradable coil.
  • the metal spring coil has a 2D primary structure or a 3D secondary structure.
  • the degradable coil when a degradable coil is used for the spring coil, the degradable coil has a primary structure or a 3D secondary structure.
  • the material of the degradable spring coil is selected from any one of polymer coating, hydrophilic coating or biologically active material coating.
  • the metal spring coil or the degradable spring coil includes a first coil and a second coil, the first coil and the second coil are coaxially arranged, and the second coil is placed in the inner cavity of the first coil.
  • the second coil is a radiopaque coil.
  • the length of the second coil is not greater than the length of the at least one first coil.
  • the material of the first coil is a polymer material, such as polylactic acid, polyglycolic acid, lactic acid-glycolic acid copolymer, polydioxanone, polycaprolactone, polyurethane, chitosan, hyaluronic acid Any kind of acid.
  • a polymer material such as polylactic acid, polyglycolic acid, lactic acid-glycolic acid copolymer, polydioxanone, polycaprolactone, polyurethane, chitosan, hyaluronic acid Any kind of acid.
  • the material of the first coil can also be selected from metal materials, and the metal material is any one of magnesium and its alloys, and iron and its alloys.

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Abstract

本发明公开了一种电解脱弹簧圈推送杆端部结构及其解脱系统、栓塞系统，所述电解脱弹簧圈推送杆端部结构包括至少一金属丝、至少一第一导电管、至少一绝缘部及至少一第二导电管；所述至少一绝缘部分别与所述第一导电管和所述第二导电管连接，并用于将所述第一导电管和所述第二导电管电绝缘；及所述至少一金属丝的一端与所述至少一第二导电管电连接。第一导电管与第二导电管同轴装配成一体式结构，该一体式结构可插入电解装置中形成回路，简化医生的操作步骤，缩短了弹簧圈的解脱时间，提高了手术效率，避免了传统电解脱需要患者身体插针的情况，降低了患者的创伤和痛苦。

Description

电解脱弹簧圈推送杆端部结构及其解脱系统、栓塞系统 技术领域
本发明涉及医疗器械领域，特别是涉及一种电解脱弹簧圈推送杆端部结构及其解脱系统、栓塞系统。
背景技术
近年来，颅内动脉瘤的发病率逐步升高，成为一种常见疾病，并且该病的致死、致残率较高，不容小觑。颅内动脉瘤的治疗手段分为两种：一是外科夹闭手术，另一种是血管内介入治疗，外科手术中动脉瘤破裂的风险较大，而血管内介入治疗具有创伤小、风险小并发症少等优点，越来越受人们的关注和重视。
动脉瘤介入治疗主要采用弹簧圈栓塞技术，其原理是利用可植入弹簧圈在动脉瘤内致密栓塞，达到扰流的目的，并促进瘤内形成血栓，实现颅内动脉瘤的治疗。植入弹簧圈需要依靠输送系统(推送杆)进行推送，当植入弹簧圈达到动脉瘤部位后，再进行解脱，使植入弹簧圈与输送系统分离，最后撤出输送系统(推送杆)。
传统的动脉瘤介入治疗产品Guglielmi Detachable Coil(GDC)采用电解脱方式，将电解脱弹簧圈推送杆端部结构正极接在弹簧圈输送导丝金属裸露区，然后把负极连接钢针插入患者皮下，电解脱弹簧圈推送杆端部结构供电，通过人体形成回路，使正极输送导丝金属裸露区溶解，完成解脱。该种电解脱方式虽然稳定可靠，但操作步骤比较复杂，解脱时间较长，并且皮下插针还会给患者带来额外的创伤和痛苦。
发明内容
针对上述现有技术的缺点，本发明的目的是提供一种电解脱弹簧圈推送杆端部结构及其解脱系统、栓塞系统。相对于现有技术来说，本发明可以避免传统电解脱弹簧圈结构需要在病人身体插针的形式，降低插针给患者带来的痛苦，且简化了医生的操作方式。
为实现上述目的，本发明的技术方案如下：
一种电解脱弹簧圈推送杆端部结构，包括至少一金属丝、至少一第一导电管、至少一绝缘部及至少一第二导电管；
所述至少一绝缘部分别与所述第一导电管和所述第二导电管连接，并用于将所述第一导电管和所述第二导电管电绝缘，所述第一导电管和所述第二导电管同轴装配；及
所述至少一金属丝的一端与所述至少一第二导电管电连接。
可选的，还包括至少一限位结构，所述至少一金属丝的一端与至少一限位结构连接。
可选的，还包括在所述第二导电管端部成型的至少一固定结构，所述至少一固定结构与所述至少一金属丝连接。
可选的，所述金属丝具有一近段、一远段及一中间段，所述中间段位于所述近段与远段之间。
可选的，所述金属丝的材质选自金、银、铜、铂、不锈钢中的一种或多种。
可选的，所述金属丝的直径范围为0.04～0.08mm，所述金属丝的长度范围为1600～2400mm。
可选的，所述金属丝的近段位于所述第二导电管的管腔内，所述金属丝的中间段位于第一导电管的管腔内，所述金属丝的远段位于管的管腔外。
可选的，所述金属丝的近段的至少部分为未涂绝缘涂层的第一裸露金属丝，所述第一裸露金属丝分别与限位结构和固定结构接触，所述第一裸露金属丝的长度范围为10～50mm。
可选的，所述金属丝的中间段涂绝缘涂层，所述金属丝中间段的长度范围为1550～2200mm。
可选的，所述金属丝远段的长度范围为50～200mm。
可选的，所述金属丝的远段具有未涂绝缘涂层的第二裸露金属丝，所述第二裸露金属丝构成用以通过电介质溶液环境与第一导电管形成解脱回路的解脱结构，所述解脱结构的长度范围为0.01～0.08mm。
可选的，所述第一导电管和第二导电管均由金属管制成。
可选的，所述第一导电管和第二导电管的外径范围为0.30～0.45mm，内径范围为0.15～0.35mm。
可选的，所述第一导电管的长度范围为1400～2000mm，所述第二导电管的长度范围为200～400mm。
可选的，所述第一导电管和所述第二导电管直接连接，所述绝缘部设置于所述第一导电管和第二导电管的连接处。
可选的，所述第一导电管与所述第二导电管之间互相嵌接。
可选的，所述嵌接使所述第一导电管或第二导电管的端部具有至少一嵌入端，所述至少一嵌入端的长度范围为10～40mm。
可选的，所述绝缘部采用绝缘热缩管或绝缘材料。
可选的，所述绝缘热缩管的一端套在第一导电管一端的外圈，所述绝缘热缩管的另一端伸入第二导电管一端的内圈；或所述绝缘热缩管的一端套在第二导电管一端的外圈，所述绝缘热缩管的另一端伸入第一导电管一端的内圈。
可选的，所述绝缘材料喷涂在第一导电管与第二导电管的连接处。
可选的，所述绝缘材料的材质选自聚酰亚胺涂层、氧化铝陶瓷涂层、陶瓷聚合物涂层、聚苯并咪唑涂层、聚四氟乙烯涂层中的任意一种。
可选的，所述第一导电管和所述第二导电管通过所述绝缘部间接连接。
可选的，所述绝缘部采用包套使所述第一导电管与所述第二导电管连接。
可选的，所述包套覆盖在所述第一导电管与第二导电管的连接处外圈，所述第一导电管与第二导电管的连接处互相对接或互相搭接。
可选的，所述包套的长度范围为20～60mm，所述包套的厚度为0.05～0.1mm。
可选的，所述绝缘部采用套管使第一导电管与所述第二导电管连接。
可选的，所述套管的长度范围为20～60mm，所述套管的厚度范围为0.1～0.15mm。
可选的，所述绝缘部采用插座结构或螺母结构使所述第一导电管与第二导电管连接。
可选的，所述至少一限位结构采用圆环、圆柱、方柱或带孔圆柱、带孔 方柱及带孔球体中的任意一种，和/或，所述限位结构(5)材料选自金，银，铜，铂金，铂钨及铂铱中的一种或多种。
可选的，所述至少一限位结构位于所述第二导电管的内部；所述至少一限位结构与所述第二导电管的端面共面齐平；所述至少一限位结构位于所述第二导电管的端部之外。
可选的，位于所述第二导电管端部之外的所述至少一限位结构与所述第二导电管端部之间的距离范围为0～2mm。
可选的，所述至少一限位结构与所述第二导电管之间采用胶粘、焊接或插销连接。
可选的，所述固定结构的一端延伸至第二导电管的管腔内并将限位结构及金属丝的一端包覆。
可选的，所述固定结构选自导电粘性材料。
可选的，所述导电粘性材料固化后形成半球形或椭球形。
可选的，所述半球形的半径尺寸范围为0.3～0.45mm。
可选的，所述椭球形顶端至第二导电管端部的距离范围为0.15～0.65mm。
一种具有上述弹簧圈推送杆端部结构的解脱系统，
所述解脱系统还包括解脱器，所述解脱器包括电源正极和电源负极；
所述电源负极与第一导电管构成负极电路；
所述电源正极与第二导电管和金属丝构成正极电路；及
所述金属丝远段包含解脱结构，当所述金属丝的解脱结构与第一导电管同时位于电介质溶液环境中时，负极电路和正极电路相通形成解脱回路。
可选的，所述解脱器提供直流电流或者交流电流。
一种具有上述弹簧圈推送杆端部结构的解脱系统，
所述解脱系统还包括解脱器，所述解脱器包括电源正极和电源负极；
所述电源正极与第一导电管构成正极电路；
所述电源负极与第二导电管和金属丝构成负极电路；及
所述金属丝远段包含解脱结构，当所述金属丝的解脱结构与第一导电管同时位于电介质溶液环境中时，负极电路和正极电路相通形成解脱回路。
可选的，所述解脱器提供直流电流或者交流电流。
一种具有上述弹簧圈推送杆端部结构的栓塞系统，所述栓塞系统还包括金属弹簧圈或可降解弹簧圈。
可选的，所述金属弹簧圈或可降解弹簧圈具有2D的一级结构或3D的二级结构。
可选的，所述可降解弹簧圈的材质选自聚合物涂层、亲水涂层或生物活性材料涂层中的任意一种。
可选的，所述可降解弹簧圈包括至少一第一线圈和至少一第二线圈。
可选的，所述至少一第一线圈与至少一第二线圈同轴布置，所述至少一第二线圈置于所述至少一第一线圈的内腔。
可选的，所述至少一第一线圈的材质采用聚合物材料，如聚乳酸、聚羟基乙酸、乳酸-羟基乙酸共聚物、聚对二氧杂环己酮、聚己内酯、聚氨酯、壳聚糖、透明质酸的任意一种。
可选的，所述至少一第一线圈的材质选自金属材料，所述金属材料为镁及其合金，铁及其合金中的任意一种。
可选的，所述至少一第二线圈为不透射线性线圈。
可选的，所述至少一第二线圈的长度不大于至少一第一线圈的长度。
与现有技术相比，本发明的有益技术效果如下：
(一)第一导电管与第二导电管之间设置绝缘部进行分离，有效避免短路的风险，第一导电管与第二导电管之间设置嵌接、包套连接、套管连接、插座式、螺纹式等多种连接方式，使得第一导电管与第二导电管之间形成同轴的一体式结构，其可共同插入电解装置中形成通解脱回路，完成解脱。
(二)通过设置限位结构可使金属丝勾住推送杆的第二导电管，使其与第二导电管接通，且在第二导电管上设置可导电的固定结构，不仅可以将金属丝固定，避免其位移，又可以增加金属丝与第二导电管的接触面积，避免发生断路的风险。
本发明将第一导电管与第二导电管同轴装配成一体式结构，该一体式结构可插入电解装置中形成回路，简化医生的操作步骤，缩短了弹簧圈的解脱时间，提高了手术效率，避免了传统电解脱需要患者身体插针的情况，降低了患者的创伤和痛苦。
附图说明
图1示出了本发明实施例一种电解脱弹簧圈推送杆端部结构的示意图。
图2A示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中负极嵌入正极结构示意图。
图2B示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中正极嵌入负极结构示意图。
图3A示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中正极与负极之间装配方式为对接包套式的结构示意图。
图3B示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中正极与负极之间装配方式为搭接包套式的结构示意图。
图4示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中正极与负极之间装配方式为套管式的结构示意图。
图5A示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中正极与负极之间装配方式为插座式并且正极插入负极的结构示意图。
图5B示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中正极与负极之间装配方式为插座式并且负极插入正极的结构示意图。
图6A示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中正极与负极之间装配方式为螺母式并且正极为外螺纹，负极为内螺纹的结构示意图。
图6B示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中正极与负极之间装配方式为螺母式并且正极为内螺纹，负极为外螺纹的结构示意图。
图7A示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中绝缘热缩管套在负极外部的结构示意图。
图7B示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中绝缘热缩管套在正极外部的结构示意图。
图8A示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中绝缘涂层涂覆于负极的结构示意图。
图8B示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中绝缘涂层涂覆于正极的结构示意图。
图9示出了本发明实施例一种电解脱弹簧圈推送杆端部结构中限位结构与正极通过胶粘或焊接的示意图。
图10出了本发明实施例一种电解脱弹簧圈推送杆端部结构中限位结构与正极通过插销连接的示意图。
图11出了本发明实施例一种电解脱弹簧圈推送杆端部结构中固定结构为半球形的结构示意图。
图12A出了本发明实施例一种电解脱弹簧圈推送杆端部结构中固定结构为大面积椭球形的结构示意图。
图12B出了本发明实施例一种电解脱弹簧圈推送杆端部结构中固定结构为小面积椭球形的结构示意图。
附图中标记：1、金属丝；2、第一导电管；3、绝缘部；301、绝缘热缩管；302、绝缘材料；4、第二导电管；5、限位结构；6、固定结构；7、解脱结构；8、嵌入端；9、包套；10、套管。
具体实施方式
为了使本发明的目的、技术方案及优点更加清楚明白，以下结合附图及实施例，对本发明进行进一步详细说明。应当理解，此处所描述的具体实施例仅用以解释本发明，并不用于限定本发明。
在本发明的描述中，需要理解的是，术语“中心”、“横向”、“上”、“下”“左”、“右”、“竖直”、“水平”、“顶”、“底”、“内”以及“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。
在本申请中，“近段”和“远段”是从使用产品的医生角度来看相对于彼此的元件或动作的相对方位、相对位置、方向，尽管“近段”和“远段”并非是限制性的，但是“近段”通常指该产品在正常操作过程中靠近医生的一端，而“远段”通常是指首先进入患者体内的一端。
首先参考图1，是本发明一实施例的电解脱弹簧圈推送杆端部结构示意图，所述电解脱弹簧圈推送杆端部结构包括至少一金属丝1、至少一第一导电 管2、至少一绝缘部3及至少一第二导电管4，所述至少一绝缘部3分别与所述第一导电管2和所述第二导电管4连接，并用于将所述第一导电管2和所述第二导电管4绝缘；及所述至少一金属丝1的一端与所述至少一第二导电管4电连接。
本实施例一中第一导电管2为负极，所述第二导电管4为正极，金属丝1的一端穿入中空管腔内部并勾在限位结构5上，在第二导电管4的端部还成型一固定结构6，固定结构6使金属丝1与第二导电管4牢固连接，避免产生接触不良的问题，保证第二导电管4与金属丝1通电。上述第一导电管2、第二导电管4、金属丝1、绝缘部3共同装配成一体式结构并插入解脱装置中通电形成回路，便于方便、快速、有效的完成解脱。在其他一些实施例中，第一导电管2可以为正极，所述第二导电管4可以为负极。
所述金属丝1选自导电性好的金属丝材，本实施例一中金属丝1选用不锈钢制成，所述金属丝材包括但不限于金、银、铜、铂、不锈钢中的一种或多种。如图1所示，本发明一实施例的电解脱弹簧圈推送杆端部结构中金属丝1整体分为三段且分别位于三个位置，具体为金属丝1具有一近段、一远段及一中间段，中间段位于近段与远段之间。其中，所述金属丝1的近段位于第二导电管4的管腔内，金属丝1的中间段位于第一导电管2的管腔内，金属丝1的远段位于管的管腔外，本发明对金属丝1三段的三个位置不作限制，只要能够实现与第二导电管4通电即可。
其中金属丝1的近段为未涂绝缘涂层的第一裸露金属丝，第一裸露金属丝分别与限位结构5和固定结构6接触，第一裸露金属丝的长度范围为0.1～1mm。优选的，本实施例一中第一裸露金属丝的长度范围为0.3～0.5mm。
金属丝1的中间段涂绝缘涂层，金属丝1中间段的长度范围为1550～2200mm。金属丝1远段的长度范围为10～30mm。优选的，本实施例一中金属丝1中间段的长度范围为1800～1900mm，金属丝1远段的长度范围为15～25mm。
金属丝1的远段具有未涂绝缘涂层的第二裸露金属丝，第二裸露金属丝构成用以通过电介质溶液环境(例如，体液环境)与第一导电管2形成解脱回路的解脱结构7，解脱结构7的长度范围为0.01～0.08mm。优选的，本实 施例一中解脱结构7的长度优选为0.025～0.06mm。
上述金属丝1的直径范围为0.04～0.08mm，金属丝1的长度范围为1600～2400mm。优选的，本实施例一中金属丝1的直径范围优选为0.04～0.06mm，金属丝1的长度范围优选为1800～1900mm。
接下来对本发明一实施例的电解脱弹簧圈推送杆端部结构中第一导电管2和第二导电管4的结构及连接关系作具体说明：
第一导电管2和第二导电管4可如图1、图2A或图2B中直接连接，所述绝缘部3设置于所述第一导电管2和所述第二导电管4的连接处。具体的，在图1、图2A或图2B中第一导电管2与第二导电管4的直接连接方式为互相嵌接，上述嵌接方式使第一导电管2或第二导电管4的端部具有至少一嵌入端8，所述嵌入端8的长度范围为10～40mm，所述嵌入端8尾部直径向所述嵌入端8的头部呈逐渐递减。如图2A所示，互相嵌接的方式可以是嵌入端8设置于第一导电管2上，通过第一导电管2上的嵌入端8与第二导电管4嵌接。如图2B所示，也可以是嵌入端8设置于第二导电管4上，通过第二导电管4上的嵌入端8与第一导电管2嵌接。本实施例一采用图2A的嵌接方式，优选的，在该种第一导电管2嵌入第二导电管4的嵌接方式中，嵌入端8的长度范围优选为15～20mm。在一些实施例中，嵌入端8可以为将第一导电管2或第二导电管4的延长段进行磨削得到的。
接下来对上述嵌接方式中提到的绝缘部3作具体说明：
如图7A、7B和图8A、8B所示，绝缘部3采用绝缘热缩管301或绝缘材料302。绝缘部3用于连接第一导电管2和第二导电管4，目的是将第一导电管2和第二导电管4电绝缘，防止短路的发生。
如图7A所示，当采用绝缘热缩管301时，所述绝缘热缩管301的一端套在第一导电管2一端的外圈，绝缘热缩管301的另一端伸入第二导电管4一端的内圈；或者如图7B所示，绝缘热缩管301的一端套在第二导电管4一端的外圈，绝缘热缩管301的另一端伸入第一导电管2一端的内圈。在一些实施例中，绝缘热缩管301为PET热缩管。
如图8A、图8B所示，当采用绝缘材料302时，所述绝缘材料302喷涂在第一导电管2与第二导电管4的连接处。绝缘材料302的材质选自聚酰亚 胺涂层、氧化铝陶瓷涂层、陶瓷聚合物涂层、聚苯并咪唑涂层、聚四氟乙烯涂层中的任意一种。
所述第一导电管2和所述第二导电管4也可以通过绝缘部3间接连接。
可选的，所述绝缘部3采用包套9使所述第一导电管2和所述第二导电管4连接，其中包套9覆盖在第一导电管2与第二导电管4的连接处外圈，如图3A所示，第一导电管2与第二导电管4的连接处互相对接，如图3B所示，第一导电管2与第二导电管4的连接处互相搭接。包套9的长度范围为5～30mm，包套9的厚度范围为0.005～0.1mm。
可选的，如图4所示，所述绝缘部3采用套管10使所述第一导电管2与所述第二导电管4间接连接，所述套管10的两端分别套入所述第一导电管2和第二导电管4的内圈。所述套管10的长度范围为5～30mm，套管10的厚度范围为0.1～0.15mm。
可选的，所述绝缘部3采用插座结构使所述第一导电管2与所述第二导电管4连接，如图5A所示，所述第一导电管2的端部具有插头结构，所述第二导电管4的端部具有插座结构或如图5B所示，所述第一导电管2的端部具有插座结构，所述第二导电管4的端部具有插头结构。
可选的，所述绝缘部3采用螺母结构使所述第一导电管2与所述第二导电管4连接，如图6A所示，所述第一导电管2的端部具有外螺纹，所述第二导电管4的端部具有内螺纹或如图6B所示，所述第一导电管2的端部具有内螺纹，所述第二导电管4的端部具有外螺纹。
所述第一导电管2和第二导电管4均由金属管制成。第一导电管2和第二导电管4的外径范围为0.30～0.45mm，内径范围为0.15～0.35mm。第一导电管2的长度范围为1400～2000mm，第二导电管4的长度范围为200～400mm。
接下来对本发明一实施例的电解脱弹簧圈推送杆端部结构中限位结构5作具体说明：
限位结构5的设置目的是将金属丝1近段的第一裸露金属丝勾住第二导电管4，并实现与第二导电管4电连接。所述限位结构5采用圆环、圆柱、方柱或带孔圆柱、带孔方柱及带孔球体中的任意一种，其材料包括但不限于金， 银，铜，铂金，铂钨、铂铱等。优选的，本实施例中限位结构5采用圆环。所述限位结构5在第二导电管4中的安装位置具有如下几种安装位置：
第一种安装位置：
所述限位结构5位于第二导电管4的内部。
第二种安装位置：
所述限位结构5与第二导电管4的端面共面齐平，本实施例选用第二种安装位置。
第三种安装位置：
所述限位结构5位于第二导电管4的端部之外。位于第二导电管4端部之外的所述限位结构5与第二导电管4端部之间的距离范围为0～2mm，优选的，位于第二导电管4端部之外的所述限位结构5与第二导电管4端部之间的距离范围为0.1～0.5mm。
如图9、图10所示，在上述三种安装位置中，所述限位结构5与第二导电管4之间的连接方式包括但不限于胶粘、焊接或插销连接，本实施例中限位结构5与第二导电管4之间采用焊接的连接方式。
接下来对本发明一实施例的电解脱弹簧圈推送杆端部结构中固定结构6作具体说明：
如图11、图12A和图12B所示，所述固定结构6的一端延伸至第二导电管4的管腔内并将限位结构5及金属丝1的一端包覆。固定结构6选自导电粘性材料，本实施例一种导电粘性材料采用导电胶水，该导电胶水在固化后形成半球形或椭球形，优选的，本实施例中导电胶水固化后形状为椭球形。其中半球形的半径尺寸范围为0.29～0.32mm。如图12A和图12B所示，椭球形顶端至第二导电管4端部的距离范围为0.15～0.65mm，本实施例中椭球形顶端至第二导电管4端部的优选距离范围为0.15～0.25mm。
本发明的再一实施例提供了一种具有所述弹簧圈推送杆端部结构的解脱系统，所述解脱系统还包括解脱器，所述解脱器提供直流电流或者交流电流，所述解脱器包括电源正极和电源负极；
所述电源负极与第一导电管构成负极电路；
所述电源正极与第二导电管和金属丝构成正极电路；及
所述金属丝远段包含解脱结构，当所述金属丝的解脱结构与第一导电管同时位于电介质溶液环境中时，负极电路和正极电路相通形成解脱回路。
本发明的又一实施例提供了一种具有所述弹簧圈推送杆端部结构的解脱系统，所述解脱系统还包括解脱器，所述解脱器提供直流电流或者交流电流，所述解脱器包括电源正极和电源负极；
所述电源正极与第一导电管构成正极电路；
所述电源负极与第二导电管和金属丝构成负极电路；及
所述金属丝远段包含解脱结构，当所述金属丝的解脱结构与第一导电管同时位于电介质溶液环境中时，负极电路和正极电路相通形成解脱回路。
本发明的再一实施例提供了一种栓塞系统，所述栓塞系统包括带有上述端部结构的推送杆及弹簧圈，所述弹簧圈为金属弹簧圈或可降解弹簧圈。
优选的，当弹簧圈采用金属弹簧圈时，所述金属弹簧圈具有2D的一级结构或3D的二级结构。
优选的，当弹簧圈采用可降解弹簧圈时，所述可降解弹簧圈具有的一级结构或3D的二级结构。
优选的，当弹簧采用可降解弹簧圈时，可降解弹簧圈的材质选自聚合物涂层、亲水涂层或生物活性材料涂层中的任意一种。
所述金属弹簧圈或可降解弹簧圈均包括第一线圈和第二线圈，第一线圈与第二线圈同轴布置，所述第二线圈置于第一线圈的内腔。第二线圈为不透射线性线圈。所述第二线圈的长度不大于至少一第一线圈的长度。
优选的，第一线圈的材质采用聚合物材料，如聚乳酸、聚羟基乙酸、乳酸-羟基乙酸共聚物、聚对二氧杂环己酮、聚己内酯、聚氨酯、壳聚糖、透明质酸的任意一种。
优选的，第一线圈的材质也可选自金属材料，金属材料为镁及其合金，铁及其合金中的任意一种。
以上所述实施例的各技术特征可以进行任意的组合，为使描述简洁，未对上述实施例中的各个技术特征所有可能的组合都进行描述，然而，只要这些技术特征的组合不存在矛盾，都应当认为是本说明书记载的范围。
以上所述实施例仅表达了本发明的几种实施方式，其描述较为具体和详 细，但并不能因此而理解为对发明专利范围的限制。应当指出的是，对于本领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干变形和改进，这些都属于本发明的保护范围。因此，本发明专利的保护范围应以所附权利要求为准。

Claims (32)

  1. 一种电解脱弹簧圈推送杆端部结构，其特征在于：
    包括至少一金属丝(1)、至少一第一导电管(2)、至少一绝缘部(3)及至少一第二导电管(4)；
    所述至少一绝缘部(3)分别与所述第一导电管(2)和所述第二导电管(4)连接，并用于将所述第一导电管(2)和所述第二导电管(4)电绝缘，所述第一导电管(2)和所述第二导电管(4)同轴装配；及
    所述至少一金属丝(1)的一端与所述至少一第二导电管(4)电连接。
  2. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：还包括至少一限位结构(5)，所述至少一金属丝(1)的一端与所述至少一限位结构(5)连接。
  3. 如权利要求2所述的电解脱弹簧圈推送杆端部结构，其特征在于：还包括在所述第二导电管(4)的端部成型的至少一固定结构(6)，所述至少一固定结构(6)与所述至少一金属丝(1)的一端连接。
  4. 如权利要求3所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述金属丝(1)具有一近段、一远段及一中间段，所述中间段位于所述近段与所述远段之间。
  5. 如权利要求4所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述金属丝(1)的材质选自金、银、铜、铂、不锈钢中的一种或多种，所述金属丝(1)的直径范围为0.04～0.08mm，所述金属丝(1)的长度范围为1600～2400mm。
  6. 如权利要求4所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述金属丝(1)的近段位于所述第二导电管(4)的管腔内，所述金属丝(1)的中间段位于所述第一导电管(2)的管腔内，所述金属丝(1)的远段位于所述第一导电管(2)的管腔外。
  7. 如权利要求6所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述金属丝(1)的近段的至少部分为未涂绝缘涂层的第一裸露金属丝，所述第一裸露金属丝分别与所述限位结构(5)和所述固定结构(6)接触，所述第 一裸露金属丝的长度范围为10～50mm；和/或，所述金属丝(1)的中间段涂绝缘涂层，所述金属丝(1)的中间段的长度范围为1550～2200mm；和/或，所述金属丝(1)的远段的长度范围为50～200mm。
  8. 如权利要求7所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述金属丝(1)的远段具有未涂绝缘涂层的第二裸露金属丝，所述第二裸露金属丝构成用以通过电介质溶液环境与所述第一导电管(2)形成解脱回路的解脱结构(7)，所述解脱结构(7)的长度范围为0.01～0.08mm。
  9. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述第一导电管(2)和所述第二导电管(4)均由金属管制成；和/或，所述第一导电管(2)和所述第二导电管(4)的外径范围为0.30～0.45mm，内径范围为0.15～0.35mm，所述第一导电管(2)的长度范围为1400～2000mm，所述第二导电管(4)的长度范围为200～400mm。
  10. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述第一导电管(2)和所述第二导电管(4)同轴装配成一体式结构。
  11. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述第一导电管(2)和所述第二导电管(4)直接连接，所述绝缘部(3)设置于所述第一导电管(2)和所述第二导电管(4)的连接处。
  12. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述第一导电管(2)与所述第二导电管(4)之间互相嵌接，所述嵌接使所述第一导电管(2)或所述第二导电管(4)的端部具有至少一嵌入端，所述至少一嵌入端的长度范围为10～40mm。
  13. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述绝缘部(3)采用绝缘热缩管(301)，所述绝缘热缩管(301)的一端套在所述第一导电管(2)一端的外圈，所述绝缘热缩管(301)的另一端伸入第二导电管(4)一端的内圈；或所述绝缘热缩管(301)的一端套在所述第二导电管(4)一端的外圈，所述绝缘热缩管(301)的另一端伸入所述第一导电管(2)一端的内圈。
  14. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述绝缘部(3)采用绝缘材料(302)，所述绝缘材料(302)喷涂在所述第 一导电管(2)与所述第二导电管(4)的连接处，所述绝缘材料(302)的材质选自聚酰亚胺涂层、氧化铝陶瓷涂层、陶瓷聚合物涂层、聚苯并咪唑涂层、聚四氟乙烯涂层中的任意一种。
  15. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述第一导电管(2)和所述第二导电管(4)通过所述绝缘部(3)间接连接。
  16. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述绝缘部(3)采用包套使所述第一导电管(2)与所述第二导电管(4)连接，所述包套覆盖在所述第一导电管(2)与所述第二导电管(4)的连接处外圈，所述第一导电管(2)与所述第二导电管(4)的连接处互相对接或互相搭接，所述包套的长度范围为20～60mm，所述包套的厚度为0.05～0.1mm。
  17. 如权利要求1所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述绝缘部(3)采用套管使所述第一导电管(2)与所述第二导电管(4)连接，所述套管的长度范围为20～60mm，所述套管的厚度范围为0.1～0.15mm；或，所述绝缘部采用插座结构或螺母结构使所述第一导电管(2)与所述第二导电管(4)连接。
  18. 如权利要求2所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述至少一限位结构(5)采用圆环、圆柱、方柱或带孔圆柱、带孔方柱及带孔球体中的任意一种；和/或，所述限位结构(5)材料选自金，银，铜，铂金，铂钨及铂铱中的一种或多种。
  19. 如权利要求2所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述至少一限位结构(5)位于所述第二导电管(4)的内部；所述至少一限位结构(5)与所述第二导电管(4)的端面共面齐平；所述至少一限位结构(5)位于所述第二导电管(4)的端部之外。
  20. 如权利要求19所述的电解脱弹簧圈推送杆端部结构，其特征在于：位于所述第二导电管(4)的端部之外的所述至少一限位结构(5)与所述第二导电管(4)的端部之间的距离范围为0～2mm。
  21. 如权利要求2所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述至少一限位结构(5)与所述第二导电管(4)之间采用胶粘、焊接或插销连接。
  22. 如权利要求3所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述固定结构(6)的一端延伸至所述第二导电管(4)的管腔内并将所述限位结构(5)及所述金属丝(1)的一端包覆。
  23. 如权利要求3所述的电解脱弹簧圈推送杆端部结构，其特征在于：所述固定结构(6)选自导电粘性材料，所述导电粘性材料固化后形成半球形或椭球形，所述半球形的半径尺寸范围为0.3～0.45mm，所述椭球形的顶端至所述第二导电管(4)的端部的距离范围为0.15～0.65mm。
  24. 一种具有如权利要求1至23任意一项所述弹簧圈推送杆端部结构的解脱系统，其特征在于：
    所述解脱系统还包括解脱器，所述解脱器包括电源正极和电源负极；
    所述电源负极与第一导电管构成负极电路；
    所述电源正极与第二导电管和金属丝构成正极电路；及
    所述金属丝的远段包括解脱结构，当所述金属丝的解脱结构与所述第一导电管同时位于电介质溶液环境中时，所述负极电路和所述正极电路相通形成解脱回路。
  25. 一种具有如权利要求1至23任意一项所述弹簧圈推送杆端部结构的解脱系统，其特征在于：
    所述解脱系统还包括解脱器，所述解脱器包括电源正极和电源负极；
    所述电源正极与第一导电管构成正极电路；
    所述电源负极与第二导电管和金属丝构成负极电路；及
    所述金属丝的远段包括解脱结构，当所述金属丝的解脱结构与所述第一导电管同时位于电介质溶液环境中时，所述负极电路和所述正极电路相通形成解脱回路。
  26. 如权利要求24或25所述的解脱系统，其特征在于：所述解脱器提供直流电流或者交流电流。
  27. 一种具有如权利要求1至23任意一项所述弹簧圈推送杆端部结构的栓塞系统，其特征在于：所述栓塞系统还包括金属弹簧圈或可降解弹簧圈。
  28. 如权利要求27所述的栓塞系统，其特征在于：所述金属弹簧圈或所述可降解弹簧圈具有2D的一级结构或3D的二级结构；和/或，所述可降解弹 簧圈的材质选自聚合物涂层、亲水涂层或生物活性材料涂层中的任意一种。
  29. 如权利要求27所述的栓塞系统，其特征在于：所述可降解弹簧圈包括至少一第一线圈和至少一第二线圈。
  30. 如权利要求29所述的栓塞系统，其特征在于：所述至少一第一线圈与所述至少一第二线圈同轴布置，所述至少一第二线圈置于所述至少一第一线圈的内腔；和/或，所述至少一第二线圈的长度不大于所述至少一第一线圈的长度。
  31. 如权利要求29所述的栓塞系统，其特征在于：所述至少一第一线圈的材质采用聚合物材料，如聚乳酸、聚羟基乙酸、乳酸-羟基乙酸共聚物、聚对二氧杂环己酮、聚己内酯、聚氨酯、壳聚糖、透明质酸的任意一种。
  32. 如权利要求29所述的栓塞系统，其特征在于：所述至少一第一线圈的材质选自金属材料，所述金属材料为镁及其合金，铁及其合金中的任意一种，所述至少一第二线圈为不透射线性线圈。
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