WO2021253292A1 - 穿戴式超声刺激正中神经装置 - Google Patents
穿戴式超声刺激正中神经装置 Download PDFInfo
- Publication number
- WO2021253292A1 WO2021253292A1 PCT/CN2020/096615 CN2020096615W WO2021253292A1 WO 2021253292 A1 WO2021253292 A1 WO 2021253292A1 CN 2020096615 W CN2020096615 W CN 2020096615W WO 2021253292 A1 WO2021253292 A1 WO 2021253292A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stimulating
- ultrasound
- median nerve
- wearable
- ultrasonic
- Prior art date
Links
- 210000001617 median nerve Anatomy 0.000 title claims abstract description 72
- 230000000638 stimulation Effects 0.000 title claims abstract description 30
- 238000003384 imaging method Methods 0.000 claims abstract description 38
- 210000000707 wrist Anatomy 0.000 claims abstract description 23
- 238000002604 ultrasonography Methods 0.000 claims description 87
- 230000004936 stimulating effect Effects 0.000 claims description 60
- 238000012285 ultrasound imaging Methods 0.000 claims description 14
- 230000008878 coupling Effects 0.000 claims description 10
- 238000010168 coupling process Methods 0.000 claims description 10
- 238000005859 coupling reaction Methods 0.000 claims description 10
- 238000013016 damping Methods 0.000 claims description 10
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 230000007383 nerve stimulation Effects 0.000 claims 2
- 230000000712 assembly Effects 0.000 abstract description 5
- 238000000429 assembly Methods 0.000 abstract description 5
- 230000026683 transduction Effects 0.000 abstract 4
- 238000010361 transduction Methods 0.000 abstract 4
- 230000000694 effects Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000001514 detection method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 210000000578 peripheral nerve Anatomy 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 230000008054 signal transmission Effects 0.000 description 3
- 208000012902 Nervous system disease Diseases 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004007 neuromodulation Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 208000014644 Brain disease Diseases 0.000 description 1
- 208000022540 Consciousness disease Diseases 0.000 description 1
- 206010027067 Median nerve injury Diseases 0.000 description 1
- 208000025966 Neurological disease Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 210000003423 ankle Anatomy 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 208000003295 carpal tunnel syndrome Diseases 0.000 description 1
- 208000015114 central nervous system disease Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000002591 computed tomography Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000005389 magnetism Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000003183 myoelectrical effect Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000001428 peripheral nervous system Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
Definitions
- This application relates to the technical field of medical devices, and in particular to a wearable ultrasound device for stimulating the median nerve.
- the median nerve is one of the important targets for peripheral nerve regulation and treatment of nervous system diseases.
- a large number of reports have shown that stimulating the median nerve through electrical stimulation and other methods can promote consciousness disorders caused by a variety of serious brain diseases. Wake up.
- physical stimulation acting on the median nerve can also treat diseases such as hand dysfunction and carpal tunnel syndrome caused by median injury.
- Ultrasound stimulation is a new type of neuromodulation technology in addition to electricity, magnetism, and light. Ultrasound stimulation has been extensively studied in central nervous system diseases. The latest progress has found that ultrasound stimulation also has a regulatory effect on the peripheral nervous system. However, the positioning of peripheral nerves is relatively difficult, and the selection of the stimulation site is also very critical. In addition, neuromodulation technology should be on the median nerve, which can improve neurological diseases such as disturbance of consciousness and median nerve injury.
- the use of ultrasound to stimulate the median nerve has the following problems, such as the difficulty of positioning the median nerve and the difficulty of fixing the point of ultrasound stimulation.
- a handheld ultrasound transducer is required, which not only requires a certain amount of manpower, but also limits the duration of ultrasound action, and also limits the activity of the therapist and affects the comfort of the therapist.
- the purpose of the embodiments of the present application is to provide a wearable ultrasound stimulating median nerve device, which aims to solve the problems that the existing ultrasound stimulating median nerve device is difficult to locate the median nerve and the ultrasound stimulation point is difficult to fix.
- a wearable ultrasound device for stimulating the median nerve which includes a wearable collar sleeved on a user's wrist and a number of ultrasound transducer components that are placed on the wearable collar and point to the user's wrist, each of the ultrasound transducers
- the components all include an ultrasonic stimulating element and an ultrasonic imaging element arranged adjacent to the ultrasonic stimulating element and electrically connected to an external imaging terminal.
- the ultrasonic stimulating element has a stimulation end facing the user's wrist
- the ultrasonic imaging element has an imaging end facing the user's wrist
- the imaging end is sleeved on the outside of the stimulation end and arranged in concentric circles .
- the fundamental frequency of the stimulation terminal is 500kHz-4MHz; and/or the fundamental frequency of the imaging terminal is 500kHz-4MHz.
- the inner side of the wearing loop is provided with an ultrasonic coupling layer that is in contact with the user's wrist.
- the ultrasonic coupling layer is a polyvinyl alcohol solid gel layer.
- the wearable ultrasound stimulating median nerve device further includes an ultrasound stimulation signal generator for electrical connection with the ultrasound stimulator.
- the wearable ultrasound stimulating median nerve device further includes an ultrasound imaging signal generator and an imaging display, both of which are electrically connected to the ultrasound imaging device.
- the wearable ultrasound stimulating median nerve device further includes an auxiliary feedback device for collecting physiological data of the user, and the auxiliary feedback device feeds back the physiological data signal of the current user to the ultrasound stimulator.
- the wearing collar includes an upper fixing ring, a rotating ring, and a lower fixing ring that are sequentially stacked in a radial direction, and the rotation surrounds the central axis and is fixed between the upper fixing ring and the lower fixing ring.
- the rings are damped to rotate, and each of the ultrasonic transducer components is penetrated on the rotating ring.
- the wearing collar further includes a first damping bearing set between the upper fixed ring and the rotating ring, and a first damping bearing set between the lower fixed ring and the rotating ring.
- the second damping bearing group is a first damping bearing set between the upper fixed ring and the rotating ring.
- the wearing loop includes a first semicircular ring and a second semicircular ring that are detachably connected.
- a magnetic attraction member is provided at the connection between the first semicircular ring and the second semicircular ring.
- a positioning guide structure is provided at the connection between the first semicircular ring and the second semicircular ring.
- the positioning and guiding structure includes a convex portion provided on the first semicircular ring and a concave portion opened on the second semicircular ring, and the convex portion is adapted to the concave portion .
- a snap structure is provided at the connection between the first semicircular ring and the second semicircular ring.
- the ultrasound transducer assembly is fixed by the wearable collar worn on the user's wrist, which is simple and convenient, and realizes the stable ultrasound energy of the ultrasound transducer.
- the ultrasound imaging device is used to emit ultrasound energy and receive ultrasound energy to obtain the position image of the median nerve, and the position is adjusted by rotating the wear collar, and finally, the ultrasound stimulator is used to send ultrasound energy to the median nerve At the place, it regulates the median nerve.
- Fig. 1 is a cross-sectional view of a wearable ultrasound device for stimulating the median nerve according to an embodiment of the present application
- FIG. 2 is a cross-sectional view of a wearable ultrasound device for stimulating the median nerve according to an embodiment of the present application
- Figure 3 is an exploded view of a wearable ultrasound stimulating median nerve device provided by an embodiment of the present application.
- FIG. 4 is a cross-sectional view of a wearable ultrasound stimulating median nerve device provided by an embodiment of the present application.
- Fig. 5 is a schematic structural diagram of a wearable ultrasound stimulating median nerve device provided by an embodiment of the present application.
- Fig. 6 is a schematic structural diagram of a wearable ultrasound stimulating median nerve device provided by an embodiment of the present application.
- Fig. 7 is a schematic structural diagram of a wearable ultrasound stimulating median nerve device provided by an embodiment of the present application.
- the wearable ultrasound device for stimulating the median nerve includes a wearable collar 10 and a number of ultrasonic transducer components 20 that are pierced through the wearable collar 10 and point to the user's wrist. Understandably, the wearable collar It can be worn on the user's wrist, ankle, etc., as well as on the user's neck and neck.
- Each ultrasonic transducer assembly 20 includes an ultrasonic stimulating element 21 and an ultrasonic imaging element 22 arranged adjacent to the ultrasonic stimulating element 21 and electrically connected to an external imaging terminal. Understandably, during use, the wearing loop 10 is sleeved on the user's wrist.
- the number of ultrasonic transducer components 20 can be one or more, and they are fixed on the wearing loop 10.
- the ultrasonic stimulating element 21 has a generating end of ultrasonic energy, transmits the emitted ultrasonic energy to the median nerve, and plays a regulatory role on the median nerve.
- the ultrasonic imaging component 22 has an ultrasonic energy generating end and a receiving end, and transmits the received ultrasonic signal to an imaging terminal of an external device, so as to obtain a position image of the median nerve.
- the wearable ultrasound device for stimulating the median nerve of the present application fixes the ultrasound transducer assembly 20 through the wearable collar 10 worn on the user's wrist, which is simple and convenient, and realizes the stable output of the ultrasound energy of the ultrasound transducer.
- the ultrasound imaging component 22 emits ultrasound energy and receives ultrasound energy to obtain a position image of the median nerve, and adjusts the position by rotating the wear collar 10, and finally, uses the ultrasound stimulator 21 therein to send ultrasound energy to the median nerve, Play a regulatory role on the median nerve. That is, the wearable ultrasound device for stimulating the median nerve can well solve the technical problems that the median nerve is difficult to locate and the ultrasound stimulation point is difficult to fix.
- the ultrasonic imaging member 22 has a tubular structure, which is sleeved on the outer side of the ultrasonic stimulating member 21, so that the ultrasonic imaging member 22 can receive ultrasonic energy in all directions, thereby obtaining a more precise centering. Image of the location of the nerve.
- the ultrasonic imaging element can also be arranged adjacently around the circumferential direction of the side wall of the ultrasonic stimulating element 21.
- the ultrasonic stimulating element 21 has a stimulating end 21a facing the user's wrist
- the ultrasonic imaging element 22 has an imaging end 22a facing the user's wrist
- the imaging end 22a is sleeved on the stimulating end 21a.
- the outer side is concentrically arranged.
- the ultrasonic imaging element 22 and the ultrasonic stimulating element 21 are in a sleeved positional relationship, so that the imaging end 22a surrounds the stimulation end 21a and is arranged in concentric circles, that is, the imaging end 22a can also receive feedback from the stimulation end 21a.
- the ultrasound signal is used to assist the ultrasound imaging device 22 in determining the position of the median nerve.
- the ultrasonic stimulating element 21 and the ultrasonic imaging element 22 may also have other combined forms, for example, the imaging end 22a and the stimulating end 21a are arranged side by side in abutment.
- the stimulation end 21a can select different ultrasonic frequencies and different focusing effects, so as to obtain different output energy, focal spot size, and focal length.
- the fundamental frequency of the stimulation terminal 21a is 500kHz ⁇ 4MHz.
- the imaging end 22a can select different ultrasound frequencies and different focusing effects to obtain different output energy, focal spot size, and focal length.
- the fundamental frequency of the imaging end 22a is 500kHz-4MHz.
- the inner side of the wearing loop 10 is provided with an ultrasonic coupling layer 30 that is in contact with the user's wrist.
- the ultrasonic coupling layer 30 can better transmit ultrasonic energy to the human tissue, and the thickness of the ultrasonic coupling layer 30 can be adjusted according to actual needs, so as to better fix the user's wrist and achieve a positioning effect.
- the ultrasonic coupling layer 30 is a polyvinyl alcohol solid gel layer. Of course, it can also be other ultrasonic coupling materials.
- the wearable ultrasound stimulating median nerve device further includes an ultrasound stimulation signal generator 40 for electrical connection with the ultrasound stimulator 21. Understandably, the ultrasonic stimulation signal generator 40 transmits the electrical signal to the ultrasonic stimulator 21 through the signal transmission line, thereby generating the ultrasonic signal, and finally transmitting it to the median nerve.
- the wearable ultrasound device for stimulating the median nerve further includes an ultrasound imaging signal generator 51 and an imaging display 52 that are electrically connected to the ultrasound imaging member 22.
- the ultrasonic imaging signal generator 51 transmits electrical signals to the ultrasonic imaging member 22 through a signal transmission line, thereby generating ultrasonic signals, which are transmitted to human tissues, and at the same time, the feedback ultrasonic signals are transmitted to the imaging display 52 through the signal transmission line. It is used to detect the position of the median nerve, and the detection position of the ultrasound imaging member 22 can be adjusted by rotating the wear collar 10 during the detection process.
- the wearable ultrasound device for stimulating the median nerve further includes an auxiliary feedback device 60 for collecting physiological data of the user, and the auxiliary feedback device 60 feeds back the physiological data signal of the current user to the ultrasound stimulator 21.
- the auxiliary feedback device 60 can be other medical devices for detection, such as electrocardiographic scanning equipment, magnetic resonance equipment, and bioimaging equipment, etc., and the physiological data therein can be electrophysiological signals and imaging signals.
- electrophysiological The signals can be brain electrical signals, myoelectric signals, electrocardiographic signals, etc.
- the imaging signals can be magnetic resonance signals, computed tomography signals, ultrasound signals, and the like. That is, the physiological data presented by the auxiliary feedback device 60 is used as auxiliary data for locating the median nerve, thereby improving the positioning accuracy and efficiency.
- the wearing collar 10 includes an upper fixed ring 11a, a rotating ring 12a, and a lower fixed ring 13a which are sequentially stacked in the radial direction. A damped rotation is made between 11a and the lower fixed ring 13a, and each ultrasonic transducer assembly 20 is penetrated on the rotating ring 12a. Understandably, the wearing loop 10 has a "sandwich" structure.
- the wearing collar 10 further includes a first damping bearing set 14a arranged between the upper fixed ring 11a and the rotating ring 12a, and a second damping bearing set 15a arranged between the lower fixed ring 13a and the rotating ring 12a.
- first damping bearing set 14a and the second damping bearing set 15a make the rotating ring 12a relatively rotate and stably stagnate, which means that the position of the ultrasonic transducer assembly 20 can be changed while the stimulation position can be fixed. Require.
- the wearing loop 10 includes a first semicircular ring 11b and a second semicircular ring 12b that are detachably connected. Understandably, the versatility and comfort during the wearing process can be improved by the two detachable semicircular rings.
- the first semicircular ring 11b and the second semicircular ring 12b are detachably connected by magnetic attraction. That is, a magnetic attraction member 13b is provided at the junction of the first semicircular ring 11b and the second semicircular ring 12b.
- the magnetic member 13b is a magnet that can be magnetically attracted to each other, or a magnet and a metal that can be magnetically attracted to it.
- a positioning guide structure 14b is provided at the connection between the first semicircular ring 11b and the second semicircular ring 12b.
- the function of the positioning guide structure 14b is to improve the assembly speed of the first semicircular ring 11b and the second semicircular ring 12b and the stability of the connection between them.
- the positioning and guiding structure 14b includes a convex portion 14b1 provided on the first semicircular ring 11b and a concave portion 14b2 opened on the second semicircular ring 12b.
- the convex portion 14b1 matches the concave portion 14b2.
- first semicircular ring 11b and the second semicircular ring 12b are directly opened in the radial direction at the joint. According to actual usage requirements, a concave portion is provided on the first semicircular ring 11b, and a convex portion is provided on the second semicircular ring 12b.
- a buckle structure 15b is provided at the junction of the first semicircular ring 11b and the second semicircular ring 12b.
- the clamping arm 15b1 is provided on the first semicircular ring 11b
- the clamping ring 15b2 is provided on the second semicircular ring 12b.
- the position of the clamping arm and the clamping ring can be exchanged.
- the wearable ultrasound device for stimulating the median nerve of the present application is fixed at the wrist of the human body through the wearing loop 10, and the ultrasound imaging member 22 is used to emit ultrasound energy and receive ultrasound energy to obtain a position image of the median nerve. And, the position adjustment is performed by rotating the wearing collar 10, and finally, the ultrasonic stimulating member 21 therein is used to emit ultrasonic energy to the median nerve to regulate the median nerve.
- the wearing loop 10 includes a first semicircular ring 11b and a second semicircular ring 12b that are detachably connected, for example, detachably connected by means of magnetic attraction or snap connection.
- the wearing collar 10 includes an upper fixed ring 11a, a rotating ring 12a, and a lower fixed ring 13a that are sequentially stacked in the radial direction.
- the rotating ring 12a is wound around the central axis and formed between the upper fixed ring 11a and the lower fixed ring 13a. Damping rotation. That is, the position of each ultrasonic transducer assembly 20 is changed by rotating the rotating ring 12a provided with a plurality of ultrasonic transducer assemblies 20 around the axis, so as to achieve the purpose of switching the position of each ultrasonic transducer assembly 20.
- the wearable ultrasound device for stimulating the median nerve also includes an ultrasound stimulation signal generator 40 that is electrically connected to the ultrasound stimulator 21; an ultrasound imaging signal generator 51 and an imaging display 52 that are both electrically connected to the ultrasound imaging device 22; And an auxiliary feedback device 60 for collecting physiological data of the user.
- the auxiliary feedback device 60 feeds back the physiological data signal of the current user to the ultrasonic stimulator 21.
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Percussion Or Vibration Massage (AREA)
Abstract
Description
Claims (15)
- 穿戴式超声刺激正中神经装置,其特征在于,包括套设于用户腕处的穿戴套环以及穿设于所述穿戴套环且指向用户腕处的若干超声换能组件,各所述超声换能组件均包括超声刺激件以及套设于所述超声刺激件外侧的且与外设成像终端电性连接的超声成像件。
- 根据权利要求1所述的穿戴式超声刺激正中神经装置,其特征在于,所述超声刺激件具有朝向用户腕处的刺激端,所述超声成像件具有朝向用户腕处的成像端,所述成像端套设于所述刺激端的外侧且呈同心圆设置。
- 根据权利要求2所述的穿戴式超声刺激正中神经装置,其特征在于,所述刺激端的使用基频为500kHz~4MHz;和/或,所述成像端的使用基频为500kHz~4MHz。
- 根据权利要求1所述的穿戴式超声刺激正中神经装置,其特征在于,所述穿戴套环的内侧设有与用户腕处相接触的超声耦合层。
- 根据权利要求4所述的穿戴式超声刺激正中神经装置,其特征在于,所述超声耦合层为聚乙烯醇固体凝胶层。
- 根据权利要求1所述的穿戴式超声刺激正中神经装置,其特征在于,所述穿戴式超声刺激正中神经装置还包括用于与所述超声刺激件电性连接的超声刺激信号发生器。
- 根据权利要求1所述的穿戴式超声刺激正中神经装置,其特征在于,所述穿戴式超声刺激正中神经装置还包括均与所述超声成像件电性连接的超声成像信号发生器以及成像显示器。
- 根据权利要求1所述的穿戴式超声刺激正中神经装置,其特征在于,所述穿戴式超声刺激正中神经装置还包括用于采集用户生理数据的辅助反馈装置,所述辅助反馈装置向所述超声刺激件反馈当前用户的生理数据信号。
- 根据权利要求1至8任一项所述的穿戴式超声刺激正中神经装置,其特征在于,所述穿戴套环包括沿径向方向依次层叠设置的上固定环、转动环以及下固定环,所述转动环绕于中轴线且于所述上固定环与所述下固定环之间做阻尼转动,各所述超声换能组件穿设于所述转动环上。
- 根据权利要求9所述的穿戴式超声刺激正中神经装置,其特征在于,所述穿戴套环还包括设于所述上固定环与所述转动环之间的第一阻尼轴承组,以及设于所述下固定环与所述转动环之间的第二阻尼轴承组。
- 根据权利要求1至8任一项所述的穿戴式超声刺激正中神经装置,其特征在于,所述穿戴套环包括可拆卸连接地第一半圆环和第二半圆环。
- 根据权利要求11所述的穿戴式超声刺激正中神经装置,其特征在于,所述第一半圆环与所述第二半圆环的连接处设有磁吸件。
- 根据权利要求11所述的穿戴式超声刺激正中神经装置,其特征在于,所述第一半圆环与所述第二半圆环的连接处设有定位导向结构。
- 根据权利要求13所述的穿戴式超声刺激正中神经装置,其特征在于,所述定位导向结构包括设于所述第一半圆环上的凸部以及开设于所述第二半圆环上的凹部,所述凸部与所述凹部相适配。
- 根据权利要求11所述的穿戴式超声刺激正中神经装置,其特征在于,所述第一半圆环与所述第二半圆环的连接处设有卡扣结构。
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1039351A (zh) * | 1988-07-12 | 1990-02-07 | 约翰·帕特里克·麦卡锡 | 监督装置 |
WO2009051965A1 (en) * | 2007-10-14 | 2009-04-23 | Board Of Regents, The University Of Texas System | A wireless neural recording and stimulating system for pain management |
CN109998595A (zh) * | 2019-04-30 | 2019-07-12 | 苏州科技城医院 | 一种基于超声多普勒的诊脉系统及诊脉方法 |
CN110167630A (zh) * | 2016-09-19 | 2019-08-23 | Nyx科技有限公司 | 多功能闭环神经反馈刺激设备及其方法 |
-
2020
- 2020-06-17 WO PCT/CN2020/096615 patent/WO2021253292A1/zh active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1039351A (zh) * | 1988-07-12 | 1990-02-07 | 约翰·帕特里克·麦卡锡 | 监督装置 |
WO2009051965A1 (en) * | 2007-10-14 | 2009-04-23 | Board Of Regents, The University Of Texas System | A wireless neural recording and stimulating system for pain management |
CN110167630A (zh) * | 2016-09-19 | 2019-08-23 | Nyx科技有限公司 | 多功能闭环神经反馈刺激设备及其方法 |
CN109998595A (zh) * | 2019-04-30 | 2019-07-12 | 苏州科技城医院 | 一种基于超声多普勒的诊脉系统及诊脉方法 |
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