WO2021226955A1 - Transient elasticity measurement method, acoustic attenuation parameter measurement method, and ultrasound imaging system - Google Patents

Transient elasticity measurement method, acoustic attenuation parameter measurement method, and ultrasound imaging system Download PDF

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WO2021226955A1
WO2021226955A1 PCT/CN2020/090336 CN2020090336W WO2021226955A1 WO 2021226955 A1 WO2021226955 A1 WO 2021226955A1 CN 2020090336 W CN2020090336 W CN 2020090336W WO 2021226955 A1 WO2021226955 A1 WO 2021226955A1
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ultrasonic
measured object
target area
frequency
measurement
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PCT/CN2020/090336
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French (fr)
Chinese (zh)
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李双双
李金洋
鲁慧瑛
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深圳迈瑞生物医疗电子股份有限公司
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Priority to CN202080053436.0A priority Critical patent/CN114144119A/en
Priority to PCT/CN2020/090336 priority patent/WO2021226955A1/en
Publication of WO2021226955A1 publication Critical patent/WO2021226955A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings

Abstract

A transient elasticity measurement method, an acoustic attenuation parameter measurement method, and an ultrasound imaging system, the transient elasticity measurement method comprising: determining an elasticity measurement ultrasound frequency suitable for an object to be measured (S310); applying mechanical vibration to the object to be measured to produce a shear wave in a target area of the object to be measured (S320); by means of an ultrasound probe comprising a plurality of array elements, using the elasticity measurement ultrasound frequency to transmit to the target area an ultrasonic wave tracking the shear wave, and receiving an ultrasound echo of the target area to acquire ultrasound echo data (S330); and, on the basis of the ultrasound echo data, acquiring a transient elasticity measurement result of the target area (S340). Different elasticity measurement ultrasound frequencies or acoustic attenuation parameter measurement ultrasound frequencies can be selected on the basis of the actual requirements of the object to be measured without changing the probe, thereby meeting clinical detection requirements for different penetration powers and resolutions.

Description

瞬时弹性测量方法、声衰减参数测量方法和超声成像系统Instantaneous elasticity measurement method, sound attenuation parameter measurement method and ultrasonic imaging system
说明书manual
技术领域Technical field
本申请涉及超声成像技术领域,更具体地涉及一种瞬时弹性测量方法、声衰减参数测量方法和超声成像系统。This application relates to the technical field of ultrasound imaging, and more specifically to an instantaneous elasticity measurement method, a sound attenuation parameter measurement method, and an ultrasound imaging system.
背景技术Background technique
超声弹性成像是近年来临床研究关心的热点之一,其主要反映组织的弹性或软硬程度,在组织癌症病变的辅助检测、良恶性判别、预后恢复评价等方面得到越来越多的应用。Ultrasound elastography is one of the hotspots of clinical research in recent years. It mainly reflects the elasticity or softness of tissues. It has been increasingly used in the auxiliary detection of tissue cancer lesions, the discrimination of benign and malignant, and the evaluation of prognosis recovery.
超声弹性成像主要通过对感兴趣区域内的弹性相关参数进行成像,从而反映组织的软硬程度。近二十年来,已经出现了许多种不同的弹性成像方法,例如基于探头按压组织造成应变的准静态弹性成像,基于声辐射力产生剪切波的剪切波弹性成像或弹性测量,基于外部振动产生剪切波的瞬时弹性成像等。Ultrasound elastography mainly uses imaging of the elasticity-related parameters in the region of interest to reflect the softness and hardness of the tissue. In the past two decades, many different elastography methods have emerged, such as quasi-static elastography based on the strain caused by the probe pressing on the tissue, shear wave elastography or elastic measurement based on shear waves generated by acoustic radiation force, and based on external vibration Instantaneous elastography that produces shear waves, etc.
其中,瞬时弹性成像主要通过超声无创检测的方法反映组织的弹性或软硬程度,在临床肝病检测,尤其是肝纤维化程度的辅助诊断中受到医生的广泛欢迎。以肝脏检查为例,其一般通过控制特殊的探头在接触体表时进行外部振动从而产生剪切波传入组织深处,再向组织发射轴向超声波并持续一段时间接收回波信号,获取剪切波的传播信息,最后计算出剪切波的传播速度并得到组织定量弹性结果。Among them, transient elastography mainly reflects the elasticity or softness of tissues through non-invasive ultrasound detection, and is widely welcomed by doctors in clinical liver disease detection, especially in the auxiliary diagnosis of liver fibrosis. Taking liver examination as an example, it generally controls a special probe to vibrate when it touches the surface of the body to generate shear waves that are transmitted to the depths of the tissue, and then transmit axial ultrasonic waves to the tissue and receive echo signals for a period of time to obtain shear waves. The propagation information of the shear wave, and finally the propagation velocity of the shear wave is calculated and the result of the quantitative elasticity of the tissue is obtained.
目前,常规的瞬时弹性成像一般仅仅能提供一维轴向位置的组织信息,并且对于具有不同个体特征的病人来说,所所适用的测量频率或振幅等参数不同,因而需要准备多个探头以应对临床中切换频率的需求。然而,多探头的配置对于机器成本控制和操作的便利性来说都是不利的。At present, conventional instantaneous elastography generally can only provide one-dimensional axial position tissue information, and for patients with different individual characteristics, the applicable measurement frequency or amplitude and other parameters are different, so it is necessary to prepare multiple probes to Respond to the need for switching frequency in the clinic. However, the configuration of the multi-probe is disadvantageous for the cost control of the machine and the convenience of operation.
发明内容Summary of the invention
在发明内容部分中引入了一系列简化形式的概念,这将在具体实施方式部分中进一步详细说明。本发明的发明内容部分并不意味着要试图限定出所 要求保护的技术方案的关键特征和必要技术特征,更不意味着试图确定所要求保护的技术方案的保护范围。A series of simplified concepts are introduced in the content of the invention, which will be explained in further detail in the specific implementation section. The inventive content part of the present invention does not mean an attempt to limit the key features and necessary technical features of the claimed technical solution, nor does it mean an attempt to determine the protection scope of the claimed technical solution.
本申请实施例第一方面提供了一种瞬时弹性测量方法,所述方法包括:The first aspect of the embodiments of the present application provides an instantaneous elasticity measurement method, the method includes:
确定适用于被测对象的弹性测量超声频率;Determine the elastic measurement ultrasonic frequency suitable for the measured object;
对所述被测对象施加机械振动,以在所述被测对象的目标区域内产生剪切波;Applying mechanical vibration to the measured object to generate a shear wave in the target area of the measured object;
通过包括多个阵元的超声探头,采用所述弹性测量超声频率向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超声回波,以获得超声回波数据;Using the elastic measuring ultrasonic frequency to transmit ultrasonic waves that track the shear wave to the target area by using an ultrasonic probe including a plurality of array elements, and receive ultrasonic echoes of the target area to obtain ultrasonic echo data;
根据所述超声回波数据获得所述目标区域的瞬时弹性测量结果。Obtain the instantaneous elasticity measurement result of the target area according to the ultrasonic echo data.
本申请实施例第二方面提供一种声衰减参数测量方法,所述方法包括:A second aspect of the embodiments of the present application provides a method for measuring sound attenuation parameters, the method including:
确定适用于被测对象的声衰减参数测量频率;Determine the sound attenuation parameter measurement frequency suitable for the measured object;
通过包括多个阵元的超声探头,采用所述声衰减参数测量频率向所述被测对象的目标区域发射超声波,并接收所述目标区域的超声回波,以获得超声回波数据;Using the acoustic attenuation parameter measurement frequency to transmit ultrasonic waves to the target area of the measured object by using an ultrasonic probe including a plurality of array elements, and receive ultrasonic echoes of the target area to obtain ultrasonic echo data;
根据所述超声回波数据获得所述目标区域的声衰减参数测量结果。Obtain the sound attenuation parameter measurement result of the target area according to the ultrasonic echo data.
本申请实施例第三方面提供一种弹性测量方法,所述方法包括:The third aspect of the embodiments of the present application provides an elasticity measurement method, the method includes:
基于包括多个阵元的超声探头,依次采用至少两个弹性测量超声频率向被测对象的目标区域发射跟踪剪切波的超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;Based on an ultrasound probe that includes a plurality of array elements, at least two elasticity measurement ultrasound frequencies are used in sequence to transmit shear wave-tracking ultrasound to the target area of the object to be measured, and receive the ultrasound echoes of the target area to obtain at least two sets Ultrasonic echo data;
根据所述超声回波数据获得每个所述超声频率下的所述目标区域的弹性测量结果;Obtaining an elasticity measurement result of the target area at each ultrasonic frequency according to the ultrasonic echo data;
综合至少两个所述弹性测量结果,以确定综合弹性测量结果。At least two of the elasticity measurement results are combined to determine a comprehensive elasticity measurement result.
本申请实施例第四方面提供一种声衰减参数测量方法,所述方法包括:A fourth aspect of the embodiments of the present application provides a method for measuring sound attenuation parameters, the method including:
基于包括多个阵元的超声探头,依次采用至少两个声衰减参数测量频率向被测对象的目标区域发射超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;Based on an ultrasonic probe including multiple array elements, at least two acoustic attenuation parameter measurement frequencies are used to transmit ultrasonic waves to the target area of the object to be measured, and receive ultrasonic echoes of the target area to obtain at least two sets of ultrasonic echo data ;
根据所述超声回波数据获得每个所述超声频率下的所述目标区域的声衰减参数测量结果;Obtaining, according to the ultrasonic echo data, a measurement result of the sound attenuation parameter of the target area at each of the ultrasonic frequencies;
综合至少两个所述声衰减参数测量结果,以确定综合声衰减参数测量结果。At least two of the sound attenuation parameter measurement results are combined to determine a comprehensive sound attenuation parameter measurement result.
本申请实施例第五方面提供一种瞬时弹性测量方法,所述方法包括:A fifth aspect of the embodiments of the present application provides a method for measuring instantaneous elasticity, the method including:
确定适用于被测对象的机械振动振幅,并根据所述机械振动振幅确定机械振动的驱动强度;Determine the mechanical vibration amplitude suitable for the measured object, and determine the driving strength of the mechanical vibration according to the mechanical vibration amplitude;
采用所述驱动强度对所述被测对象施加所述机械振动振幅的机械振动,以在所述被测对象的目标区域内产生剪切波;Applying the driving intensity to the measured object with the mechanical vibration of the mechanical vibration amplitude, so as to generate a shear wave in the target area of the measured object;
向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超声回波,以获得超声回波数据;Transmitting ultrasonic waves that track the shear wave to the target area, and receiving ultrasonic echoes of the target area to obtain ultrasonic echo data;
根据所述超声回波数据获得所述目标区域的瞬时弹性测量结果。Obtain the instantaneous elasticity measurement result of the target area according to the ultrasonic echo data.
本申请实施例第六方面提供一种超声成像系统,所述超声成像系统包括:A sixth aspect of the embodiments of the present application provides an ultrasound imaging system, the ultrasound imaging system includes:
超声探头,所述超声探头包括多个阵元;An ultrasonic probe, the ultrasonic probe includes a plurality of array elements;
振动器,用于对被测对象施加机械振动,以在所述被测对象的目标区域内产生剪切波;A vibrator for applying mechanical vibration to the measured object to generate a shear wave in the target area of the measured object;
发射/接收电路,用于激励所述超声探头采用适用于所述被测对象的弹性测量超声频率向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超声回波,以获得超声回波数据;The transmitting/receiving circuit is used to excite the ultrasonic probe to use the elastic measurement ultrasonic frequency suitable for the measured object to transmit the ultrasonic wave tracking the shear wave to the target area, and to receive the ultrasonic echo of the target area To obtain ultrasonic echo data;
处理器,用于:Processor for:
确定所述弹性测量超声频率;以及Determining the elasticity measurement ultrasonic frequency; and
对所述超声回波数据进行处理,以获得所述目标区域的瞬时弹性测量结果;Processing the ultrasonic echo data to obtain the instantaneous elasticity measurement result of the target area;
输出设备,用于输出所述瞬时弹性测量结果。The output device is used to output the instantaneous elasticity measurement result.
本申请实施例第七方面提供一种超声成像系统,所述超声成像系统包括:A seventh aspect of the embodiments of the present application provides an ultrasound imaging system, the ultrasound imaging system includes:
超声探头,所述超声探头包括多个阵元;An ultrasonic probe, the ultrasonic probe includes a plurality of array elements;
发射/接收电路,用于激励所述超声探头依次采用至少两个弹性测量超声频率向所述目标区域发射跟踪剪切波的超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;The transmitting/receiving circuit is used to excite the ultrasonic probe to use at least two elasticity measuring ultrasonic frequencies to transmit ultrasonic waves tracking shear waves to the target area in turn, and receive ultrasonic echoes from the target area to obtain at least two sets Ultrasonic echo data;
处理器,用于:Processor for:
对所述至少两组超声回波数据进行处理,以获得所述目标区域的至少两组弹性测量结果;Processing the at least two sets of ultrasonic echo data to obtain at least two sets of elastic measurement results of the target area;
综合所述至少两组弹性测量结果,以得到综合弹性测量结果。The at least two sets of elasticity measurement results are synthesized to obtain a comprehensive elasticity measurement result.
本申请实施例第八方面提供一种超声成像系统,所述超声成像系统包括:An eighth aspect of the embodiments of the present application provides an ultrasound imaging system, the ultrasound imaging system includes:
超声探头,所述超声探头包括多个阵元;An ultrasonic probe, the ultrasonic probe includes a plurality of array elements;
发射/接收电路,用于激励所述超声探头采用适用于所述被测对象的声衰减参数测量频率向所述目标区域发射超声波,并接收所述目标区域的超声回波,以获得超声回波数据;The transmitting/receiving circuit is used to excite the ultrasonic probe to use the sound attenuation parameter measurement frequency suitable for the measured object to transmit ultrasonic waves to the target area and receive the ultrasonic echo of the target area to obtain the ultrasonic echo data;
处理器,用于:Processor for:
确定所述声衰减参数测量频率;以及Determining the sound attenuation parameter measurement frequency; and
对所述超声回波数据进行处理,以获得所述目标区域的声衰减参数测量结果;Processing the ultrasonic echo data to obtain a measurement result of the acoustic attenuation parameter of the target area;
输出设备,用于输出所述声衰减参数测量结果。The output device is used to output the measurement result of the sound attenuation parameter.
本申请实施例第九方面提供一种超声成像系统,所述超声成像系统包括:A ninth aspect of the embodiments of the present application provides an ultrasound imaging system, the ultrasound imaging system includes:
超声探头,所述超声探头包括多个阵元;An ultrasonic probe, the ultrasonic probe includes a plurality of array elements;
发射/接收电路,用于激励所述超声探头依次采用至少两个声衰减参数频率向所述目标区域发射超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;A transmitting/receiving circuit for stimulating the ultrasonic probe to sequentially use at least two acoustic attenuation parameter frequencies to transmit ultrasonic waves to the target area and receive ultrasonic echoes of the target area to obtain at least two sets of ultrasonic echo data;
处理器,用于:Processor for:
对所述至少两组超声回波数据进行处理,以获得所述目标区域的至少两组声衰减参数测量结果;Processing the at least two sets of ultrasonic echo data to obtain at least two sets of sound attenuation parameter measurement results of the target area;
综合所述至少两组声衰减参数测量结果,以得到综合声衰减参数测量结果;Synthesize the at least two sets of sound attenuation parameter measurement results to obtain a comprehensive sound attenuation parameter measurement result;
输出设备,由于输出所述综合声衰减参数测量结果。The output device outputs the measurement result of the comprehensive sound attenuation parameter.
根据本申请实施例的瞬时弹性测量方法、声衰减参数测量方法和超声成像系统,通过使用包括多个阵元的超声探头,可以在不切换探头的情况下,根据被测对象的实际需要选择不同的弹性测量超声频率或声衰减参数测量超声频率,从而满足临床中对不同的穿透力和分辨率的检测需求,提升了弹性测量的有效性,同时操作简便,并且有利于节约成本。According to the instantaneous elasticity measurement method, the acoustic attenuation parameter measurement method, and the ultrasonic imaging system of the embodiments of the present application, by using an ultrasonic probe that includes multiple array elements, it is possible to select different options according to the actual needs of the measured object without switching the probe. The elasticity measures the ultrasonic frequency or the acoustic attenuation parameter to measure the ultrasonic frequency, so as to meet the detection requirements of different penetration and resolution in the clinic, improve the effectiveness of the elasticity measurement, and at the same time, it is easy to operate and is beneficial to cost saving.
附图说明Description of the drawings
为了更清楚地说明本申请实施例中的技术方案,下面将对实施例描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本发明的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动性 的前提下,还可以根据这些附图获得其他的附图。In order to more clearly describe the technical solutions in the embodiments of the present application, the following will briefly introduce the drawings used in the description of the embodiments. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained from these drawings without creative labor.
在附图中:In the attached picture:
图1示出根据本申请实施例的超声成像系统的示意性框图;Fig. 1 shows a schematic block diagram of an ultrasound imaging system according to an embodiment of the present application;
图2示出根据本发明一实施例的超声探头的灵敏度示意图;Fig. 2 shows a schematic diagram of the sensitivity of an ultrasonic probe according to an embodiment of the present invention;
图3示出根据本发明一实施例的瞬时弹性测量方法的示意性流程图;Fig. 3 shows a schematic flowchart of a method for measuring instantaneous elasticity according to an embodiment of the present invention;
图4示出根据本发明一实施例的超声波的幅度与传播深度的关系图;Fig. 4 shows a diagram of the relationship between the amplitude of ultrasonic waves and the depth of propagation according to an embodiment of the present invention;
图5示出根据本发明一实施例的声衰减参数测量方法的示意性流程图;FIG. 5 shows a schematic flowchart of a method for measuring sound attenuation parameters according to an embodiment of the present invention;
图6示出根据本发明另一实施例的超声成像系统的示意性框图;Fig. 6 shows a schematic block diagram of an ultrasound imaging system according to another embodiment of the present invention;
图7示出根据本发明一实施例的弹性测量方法的示意性流程图;FIG. 7 shows a schematic flowchart of a method for measuring elasticity according to an embodiment of the present invention;
图8示出根据本发明一实施例的声衰减参数测量方法的示意性流程图;FIG. 8 shows a schematic flowchart of a method for measuring sound attenuation parameters according to an embodiment of the present invention;
图9示出根据本发明一实施例的瞬时弹性测量方法的示意性流程图。Fig. 9 shows a schematic flowchart of a method for measuring instantaneous elasticity according to an embodiment of the present invention.
具体实施方式Detailed ways
为了使得本申请的目的、技术方案和优点更为明显,下面将参照附图详细描述根据本申请的示例实施例。显然,所描述的实施例仅仅是本申请的一部分实施例,而不是本申请的全部实施例,应理解,本申请不受这里描述的示例实施例的限制。基于本申请中描述的本申请实施例,本领域技术人员在没有付出创造性劳动的情况下所得到的所有其它实施例都应落入本申请的保护范围之内。In order to make the objectives, technical solutions, and advantages of the present application more obvious, the exemplary embodiments according to the present application will be described in detail below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments of the present application, and it should be understood that the present application is not limited by the exemplary embodiments described herein. Based on the embodiments of this application described in this application, all other embodiments obtained by those skilled in the art without creative work should fall within the protection scope of this application.
在下文的描述中,给出了大量具体的细节以便提供对本申请更为彻底的理解。然而,对于本领域技术人员而言显而易见的是,本申请可以无需一个或多个这些细节而得以实施。在其他的例子中,为了避免与本申请发生混淆,对于本领域公知的一些技术特征未进行描述。In the following description, a lot of specific details are given in order to provide a more thorough understanding of this application. However, it is obvious to those skilled in the art that this application can be implemented without one or more of these details. In other examples, in order to avoid confusion with this application, some technical features known in the art are not described.
应当理解的是,本申请能够以不同形式实施,而不应当解释为局限于这里提出的实施例。相反地,提供这些实施例将使公开彻底和完全,并且将本申请的范围完全地传递给本领域技术人员。It should be understood that this application can be implemented in different forms and should not be construed as being limited to the embodiments presented here. On the contrary, the provision of these embodiments will make the disclosure thorough and complete, and will fully convey the scope of the present application to those skilled in the art.
在此使用的术语的目的仅在于描述具体实施例并且不作为本申请的限制。在此使用时,单数形式的“一”、“一个”和“所述/该”也意图包括复数形式,除非上下文清楚指出另外的方式。还应明白术语“组成”和/或“包括”,当在该说明书中使用时,确定所述特征、整数、步骤、操作、元件和/或部件的存在,但不排除一个或更多其它的特征、整数、步骤、操作、元件、部件和/ 或组的存在或添加。在此使用时,术语“和/或”包括相关所列项目的任何及所有组合。The purpose of the terms used here is only to describe specific embodiments and not as a limitation of the present application. When used herein, the singular forms "a", "an" and "the/the" are also intended to include plural forms, unless the context clearly indicates otherwise. It should also be understood that the terms "composition" and/or "including", when used in this specification, determine the existence of the described features, integers, steps, operations, elements and/or components, but do not exclude one or more other The existence or addition of features, integers, steps, operations, elements, parts, and/or groups. As used herein, the term "and/or" includes any and all combinations of related listed items.
为了彻底理解本申请,将在下列的描述中提出详细的结构,以便阐释本申请提出的技术方案。本申请的可选实施例详细描述如下,然而除了这些详细描述外,本申请还可以具有其他实施方式。In order to thoroughly understand this application, a detailed structure will be proposed in the following description to explain the technical solution proposed by this application. The optional embodiments of the present application are described in detail as follows, however, in addition to these detailed descriptions, the present application may also have other implementation manners.
下面,首先参考图1描述根据本申请一个实施例的超声成像系统,图1示出了根据本申请实施例的超声成像系统100的示意性结构框图。Hereinafter, first, an ultrasound imaging system according to an embodiment of the present application will be described with reference to FIG. 1. FIG. 1 shows a schematic structural block diagram of an ultrasound imaging system 100 according to an embodiment of the present application.
如图1所示,超声成像系统100包括超声探头110、振动器112、发射/接收电路114、处理器116和输出设备118。进一步地,超声成像系统还可以包括波束合成电路和发射/接收选择开关,发射/接收电路114可以通过发射/接收选择开关与超声探头110连接。As shown in FIG. 1, the ultrasound imaging system 100 includes an ultrasound probe 110, a vibrator 112, a transmitting/receiving circuit 114, a processor 116 and an output device 118. Further, the ultrasound imaging system may further include a beam combining circuit and a transmission/reception selection switch, and the transmission/reception circuit 114 may be connected to the ultrasound probe 110 through the transmission/reception selection switch.
其中,在进行瞬时弹性检测时,振动器112在处理器116的控制下产生机械振动,从而在被测对象的目标区域产生在组织中传播的剪切波。振动器112可以为设置在超声探头110内部的内置式振动器,也可以是单独设置的外置式振动器。Wherein, during the instantaneous elasticity detection, the vibrator 112 generates mechanical vibration under the control of the processor 116, thereby generating a shear wave propagating in the tissue in the target area of the object to be measured. The vibrator 112 may be a built-in vibrator installed inside the ultrasonic probe 110, or may be an external vibrator provided separately.
超声探头110中设置有多个换能器(也称为多个阵元或多个换能器阵元,多个包括至少两个),用于根据电信号发射超声波,或将接收的超声回波变换为电信号。在本申请实施例中,超声探头110具有多个换能器,从而能够在较宽的频带下发射和接收超声波,而无需切换探头。多个换能器可以排列成一排构成线阵,或排布成二维矩阵构成面阵,多个换能器也可以构成凸阵、相控阵等,本申请实施例对多个换能器阵元的排布方式不做限制。换能器可根据激励电信号发射超声波,或将接收的超声波变换为电信号,因而每个换能器可用于向目标区域的组织发射超声波,也可用于接收经组织返回的超声波回波。在进行超声测量时,可通过发射/接收电路114控制哪些换能器用于发射超声波,哪些换能器用于接收超声波,或者控制换能器分时隙用于发射超声波或接收超声回波。参与超声波发射的所有换能器可以被电信号同时激励,从而同时发射超声波;或者参与超声波发射的换能器也可以被具有一定时间间隔的若干电信号激励,从而持续发射具有一定时间间隔的超声波。The ultrasonic probe 110 is provided with multiple transducers (also called multiple array elements or multiple transducer array elements, multiple including at least two), which are used to transmit ultrasonic waves according to electrical signals or return received ultrasonic waves to The wave is transformed into an electrical signal. In the embodiment of the present application, the ultrasonic probe 110 has multiple transducers, so that ultrasonic waves can be transmitted and received in a wider frequency band without the need to switch the probe. Multiple transducers can be arranged in a row to form a linear array, or arranged in a two-dimensional matrix to form an area array. Multiple transducers can also form a convex array, phased array, etc. There is no restriction on the arrangement of array elements. The transducer can transmit ultrasonic waves according to the excitation electrical signal, or convert the received ultrasonic waves into electrical signals. Therefore, each transducer can be used to transmit ultrasonic waves to the tissue in the target area, and can also be used to receive ultrasonic echoes returned through the tissue. When performing ultrasonic measurement, the transmitting/receiving circuit 114 can control which transducers are used to transmit ultrasonic waves and which transducers are used to receive ultrasonic waves, or control the transducers to be used to transmit ultrasonic waves or receive ultrasonic echoes in time slots. All the transducers participating in ultrasonic emission can be excited by electrical signals at the same time, so as to emit ultrasonic waves at the same time; or the transducers participating in ultrasonic emission can also be excited by several electrical signals with a certain time interval, so as to continuously emit ultrasonic waves with a certain time interval. .
图2示出了一种示例性的超声探头110的灵敏度频谱分布示意图。如图2所示,超声探头110的最佳灵敏度所在的频点(即峰值频率)为3.30MHz, 但其在较宽的频率范围内均具有较佳的声学灵敏度,因而能够在较宽的频带下发射和接收超声波。以6dB以上灵敏度的带宽为例,频率分布范围为最低频率(FL6)2.52MHz至最高频率(FH6)4.78MHz之间,中心频率(FC6)为2.52MHz。也就是说,选择使用该频率范围内的任意频点发射,都能得到比较好的效果。FIG. 2 shows a schematic diagram of the sensitivity spectrum distribution of an exemplary ultrasonic probe 110. As shown in Figure 2, the frequency point (ie, peak frequency) where the best sensitivity of the ultrasonic probe 110 is located is 3.30MHz, but it has better acoustic sensitivity in a wider frequency range, so it can operate in a wider frequency band. Transmit and receive ultrasound. Taking the bandwidth with a sensitivity above 6dB as an example, the frequency distribution range is from the lowest frequency (FL6) 2.52MHz to the highest frequency (FH6) 4.78MHz, and the center frequency (FC6) is 2.52MHz. In other words, if you choose to use any frequency point in the frequency range to transmit, you can get better results.
可选地,所述超声探头110中还可以包括压力传感器,用于反馈超声探头110与人体接触时的力度,方便用户控制按压松紧度,使得超声探头110产生的剪切波较好地传入组织。Optionally, the ultrasonic probe 110 may also include a pressure sensor for feeding back the strength of the ultrasonic probe 110 when it is in contact with the human body, so that the user can control the tightness of the pressing, so that the shear wave generated by the ultrasonic probe 110 can be better transmitted. organization.
发射/接收电路114用于激励超声探头110向所述目标区域发射跟踪所述剪切波的超声波,并接收到从目标区域返回的超声波所对应的超声回波,从而获得超声回波数据。之后,发射/接收电路114将超声回波的电信号送入波束合成电路,波束合成电路对超声回波数据进行聚焦延时、加权和通道求和等处理,然后送入处理器116。The transmitting/receiving circuit 114 is used to excite the ultrasonic probe 110 to transmit the ultrasonic wave tracking the shear wave to the target area, and receive the ultrasonic echo corresponding to the ultrasonic wave returned from the target area, so as to obtain ultrasonic echo data. After that, the transmitting/receiving circuit 114 sends the ultrasonic echo electrical signal to the beam synthesis circuit, and the beam synthesis circuit performs processing such as focus delay, weighting and channel summation on the ultrasonic echo data, and then sends it to the processor 116.
可选地,处理器116可以通过软件、硬件、固件或其任意组合来实现,可以使用电路、单个或多个专用集成电路(Application Specific Integrated Circuit,ASIC)、单个或多个通用集成电路、单个或多个微处理器、单个或多个可编程逻辑器件、或者前述电路和/或器件的任意组合、或者其他适合的电路或器件。并且,处理器116可以控制所述超声成像系统100中的其它组件以执行期望的功能。Optionally, the processor 116 may be implemented by software, hardware, firmware, or any combination thereof, and may use a circuit, a single or multiple application specific integrated circuits (Application Specific Integrated Circuit, ASIC), a single or multiple general integrated circuits, and a single Or multiple microprocessors, single or multiple programmable logic devices, or any combination of the foregoing circuits and/or devices, or other suitable circuits or devices. Also, the processor 116 may control other components in the ultrasound imaging system 100 to perform desired functions.
处理器116对其接收到的超声回波数据进行瞬时弹性处理,以获得所述目标区域的瞬时弹性测量数据,并可以将获得的瞬时弹性测量数据存储在存储器中。作为示例,处理器还可以根据用户所需的成像模式对发射/接收电路114获取的超声回波数据进行不同的处理,以获得不同模式的超声组织图像。在一实施例中,处理器通过对同一超声回波处理后可同时得到瞬时弹性测量数据和超声组织图像;在另一实施例中,超声探头110可以先后发射第一超声波和第二超声波或者穿插式地发射第一超声波和第二超声波,处理器116可对第一超声波的第一超声回波处理后得到瞬时弹性测量数据,并通过对第二超声波的第二超声回波处理后生成不同模式的超声组织图像。The processor 116 performs instantaneous elasticity processing on the received ultrasonic echo data to obtain instantaneous elasticity measurement data of the target area, and may store the obtained instantaneous elasticity measurement data in a memory. As an example, the processor may also perform different processing on the ultrasound echo data acquired by the transmitting/receiving circuit 114 according to the imaging mode required by the user to obtain ultrasound tissue images of different modes. In one embodiment, the processor can obtain instantaneous elasticity measurement data and ultrasound tissue images at the same time after processing the same ultrasound echo; in another embodiment, the ultrasound probe 110 can emit the first ultrasound and the second ultrasound successively or intersperse Transmit the first ultrasonic wave and the second ultrasonic wave in a manner, the processor 116 can process the first ultrasonic echo of the first ultrasonic wave to obtain instantaneous elasticity measurement data, and generate different modes after processing the second ultrasonic echo of the second ultrasonic wave. Ultrasound tissue image.
在本申请实施例中,处理器116还可以根据目标对象的个体特征选择适用的弹性测量超声频率或声衰减参数测量频率,并自动或用户手动切换选定的超声频率进行超声发射接收,从而根据不同的临床应用情况在超声穿透力 和空间分辨率之间达到较优化的平衡,提升弹性测量的准确性;处理器还可以根据目标对象的个体特征选择适用的机械振动振幅,具体参见下文。In the embodiment of the present application, the processor 116 may also select the applicable elasticity measurement ultrasonic frequency or the acoustic attenuation parameter measurement frequency according to the individual characteristics of the target object, and automatically or manually switch the selected ultrasonic frequency for ultrasonic transmission and reception, thereby Different clinical application situations achieve a more optimized balance between ultrasound penetration and spatial resolution, and improve the accuracy of elastic measurement; the processor can also select the applicable mechanical vibration amplitude according to the individual characteristics of the target object, see below for details.
输出设备118与处理器116连接,用于输出瞬时弹性测量结果或声辐射力测量结果。在一个实施例中,输出设备118可以是显示器,用于在显示界面上显示瞬时弹性测量结果。作为示例,显示器可以为触摸显示屏、液晶显示屏等,或者也可以为独立的液晶显示器、电视机等独立显示设备;或者,显示器也可以是智能手机、平板电脑等电子设备的显示屏,等等。其中,显示器的数量可以为一个或多个。The output device 118 is connected to the processor 116 for outputting the instantaneous elasticity measurement result or the acoustic radiation force measurement result. In one embodiment, the output device 118 may be a display for displaying instantaneous elasticity measurement results on the display interface. As an example, the display can be a touch screen, a liquid crystal display, etc., or can also be an independent display device such as an independent liquid crystal display, a TV, etc.; or, the display can also be a display screen of an electronic device such as a smart phone, a tablet computer, etc. Wait. Wherein, the number of displays can be one or more.
除了可以显示瞬时弹性测量结果以外,显示器还可以提供给用户进行人机交互的图形界面,在图形界面上设置一个或多个被控对象,提供给用户利用人机交互装置输入操作指令来控制这些被控对象,从而执行相应的控制操作。例如,图形界面上显示图标,利用人机交互装置可以对该图标进行操作,用来执行特定的功能。In addition to displaying instantaneous elasticity measurement results, the display can also provide users with a graphical interface for human-computer interaction. One or more controlled objects can be set on the graphical interface and provided to the user to use human-computer interaction devices to input operating instructions to control these Controlled object, so as to perform corresponding control operations. For example, an icon is displayed on a graphical interface, and the icon can be operated using a human-computer interaction device to perform a specific function.
除此之外,输出设备118还可以包括扬声器、打印机等。输出设备118也可以是其他任何合适的信息输出设备。In addition, the output device 118 may also include a speaker, a printer, and so on. The output device 118 may also be any other suitable information output device.
可选地,超声成像系统100还可以包括其他人机交互装置,其与处理器116连接,例如,处理器116可以通过外部输入/输出端口与人机交互装置连接,外部输入/输出端口可以是无线通信模块,也可以是有线通信模块,或者两者的组合。外部输入/输出端口也可基于USB、如CAN等总线协议、和/或有线网络协议等来实现。Optionally, the ultrasound imaging system 100 may also include other human-computer interaction devices, which are connected to the processor 116. For example, the processor 116 may be connected to the human-computer interaction device through an external input/output port, and the external input/output port may be The wireless communication module can also be a wired communication module, or a combination of the two. The external input/output ports can also be implemented based on USB, bus protocols such as CAN, and/or wired network protocols.
示例性地,人机交互装置可以包括输入设备,用于检测用户的输入信息,该输入信息例如可以是对超声波发射/接收时序的控制指令,可以手动切换超声频率的操作输入指令,或者还可以包括其他指令类型。输入设备可以包括键盘、鼠标、滚轮、轨迹球、移动式输入设备(比如带触摸显示屏的移动设备、手机等等)、多功能旋钮等等其中之一或者多个的结合。Exemplarily, the human-computer interaction device may include an input device for detecting user input information. The input information may be, for example, a control instruction for the timing of ultrasonic transmission/reception, an operation input instruction for manually switching the ultrasonic frequency, or Including other instruction types. The input device may include one or a combination of a keyboard, a mouse, a scroll wheel, a trackball, a mobile input device (such as a mobile device with a touch display screen, a mobile phone, etc.), a multi-function knob, and so on.
超声成像系统100还可以包括存储器,用于存储处理器执行的指令,存储瞬时弹性测量、超声图像,等等。存储器可以为闪存卡、固态存储器、硬盘等。其可以为易失性存储器和/或非易失性存储器,为可移除存储器和/或不可移除存储器等。The ultrasound imaging system 100 may also include a memory for storing instructions executed by the processor, storing instantaneous elastic measurements, ultrasound images, and so on. The memory may be a flash memory card, solid state memory, hard disk, etc. It can be a volatile memory and/or a non-volatile memory, a removable memory and/or a non-removable memory, etc.
应理解,图1所示的超声成像系统100所包括的部件只是示意性的,其可以包括更多或更少的部件,本申请对此不限定。It should be understood that the components included in the ultrasound imaging system 100 shown in FIG. 1 are only schematic, and it may include more or fewer components, which is not limited in the present application.
下面,将参考图3描述根据本申请一个实施例的瞬时弹性测量方法。图3是本申请实施例的瞬时弹性测量方法300的一个示意性流程图。Hereinafter, the instantaneous elasticity measurement method according to an embodiment of the present application will be described with reference to FIG. 3. FIG. 3 is a schematic flowchart of a method 300 for measuring instantaneous elasticity according to an embodiment of the present application.
如图3所示,所述瞬时弹性测量方法300包括如下步骤:As shown in FIG. 3, the instantaneous elasticity measurement method 300 includes the following steps:
步骤S310,确定适用于被测对象的弹性测量超声频率。Step S310: Determine the elasticity measurement ultrasonic frequency suitable for the measured object.
其中,所述被测对象包括人体,所述弹性测量超声频率指用于瞬时弹性测量的超声发射和接收频率,进一步地,该弹性测量超声频率可以是超声发射和接收的中心频率。弹性测量超声频率越高,则分辨率越高而穿透力越低,反之,弹性测量超声频率越低,则分辨率越低而穿透力越高。对于一些被测对象来说,需要较高的分辨率,而不需要过高的穿透力,而对于另外的一些被测对象来说,对分辨率要求不高,但对穿透力的要求增加。因此,确定适用于被测对象的弹性测量超声频率有利于在超声穿透力和空间分辨率之间达到较优化的平衡,提高瞬时弹性测量的有效性和准确性。Wherein, the measured object includes a human body, and the elasticity measurement ultrasonic frequency refers to the ultrasonic transmission and reception frequency used for instantaneous elasticity measurement. Further, the elasticity measurement ultrasonic frequency may be the center frequency of ultrasonic transmission and reception. The higher the ultrasonic frequency of elasticity measurement, the higher the resolution and the lower the penetrating power. Conversely, the lower the ultrasonic frequency of elasticity measurement, the lower the resolution and the higher the penetrating power. For some measured objects, higher resolution is required, but not too high penetrating power. For some other measured objects, the resolution requirements are not high, but the penetrating power requirements are not high. Increase. Therefore, determining the elastic measurement ultrasonic frequency suitable for the measured object is conducive to achieving a more optimized balance between ultrasonic penetration and spatial resolution, and improving the effectiveness and accuracy of instantaneous elastic measurement.
作为具体的实施方式,可以首先获取表征被测对象的个体特征的数据,并根据表征所述被测对象的个体特征的数据确定适用于该被测对象的弹性测量超声频率。其中,表征被测对象的个体特征的数据可以是表征被测对象身体结构特征的数据。在根据表征被测对象的个体特征的数据确定对其适用的弹性测量超声频率时,针对不同的数据,可以直接匹配到与所获得的数据关联的弹性测量超声频率,也可以对所获得的数据进行分析,并根据分析结果选择适用的弹性测量超声频率。As a specific implementation manner, the data representing the individual characteristics of the measured object may be acquired first, and the elasticity measurement ultrasonic frequency suitable for the measured object can be determined according to the data representing the individual characteristics of the measured object. Among them, the data that characterizes the individual characteristics of the measured object may be data that characterizes the physical structure of the measured object. When determining the elastic measurement ultrasonic frequency applicable to the measured object according to the data characterizing the individual characteristics of the measured object, for different data, it can be directly matched to the elastic measurement ultrasonic frequency associated with the obtained data, or the obtained data Carry out the analysis, and select the applicable elasticity measurement ultrasonic frequency according to the analysis result.
在一个示例中,表征被测对象的个体特征的数据可以包括表征被测对象的体型的数据,例如体重、胸围或腰围等。一般而言,对于体型较大或肥胖被测对象来说,组织器官(例如肝脏)的位置较深,需要较高的穿透力,因而适用于较低的弹性测量超声频率;对于正常体型的被测对象来说,组织器官的位置深度中等,因而适用于采用中等的超声频率进行发射接收;对于小体型的被测对象来说,组织器官的位置较浅,则适用于采用较高的超声频率进行发射接收。In an example, the data characterizing the individual characteristics of the measured object may include data characterizing the body shape of the measured object, such as weight, chest circumference, or waist circumference. Generally speaking, for large or obese subjects, the tissues and organs (such as the liver) are located deeper and require higher penetration, so they are suitable for lower elasticity measurement ultrasound frequencies; for normal body types For the measured object, the location depth of the tissues and organs is medium, so it is suitable for transmitting and receiving with medium ultrasound frequency; for the small-sized object to be measured, the location of the tissues and organs is shallower, so it is suitable for using higher ultrasound. Frequency for transmission and reception.
类似地,表征被测对象的个体特征的数据可以包括被测对象的年龄数据。年幼的被测对象组织器官的位置较浅,因而需要较高的弹性测量超声频率,相比而言,成年的被测对象组织器官的位置较深,因而需要较低的弹性测量超声频率。或者,表征被测对象的个体特征的数据可以包括表征被测对象肋 间距的数据:与肋间距较宽的被测对象相比,肋间距较窄的被测对象需要的穿透力较强,因而需要较低的弹性测量超声频率。此外,表征被测对象的个体特征的数据还可以包括表征被测对象健康状况的数据。例如,健康状况较差的被测对象可能需要更强的分辨率。作为示例,可以通过手动输入的方式获得表征被测对象体型、年龄、肋间距或健康状况等的数据,或者,也可以从被测对象的信息库或电子病历等自动获取上述数据。Similarly, the data characterizing the individual characteristics of the measured object may include age data of the measured object. The tissues and organs of the young test subject are shallower, and therefore require a higher ultrasonic frequency for elasticity measurement. In contrast, the tissues and organs of the adult test target are deeper in the location and therefore require a lower ultrasonic frequency for elasticity measurement. Alternatively, the data characterizing the individual characteristics of the measured object may include data characterizing the rib spacing of the measured object: compared with the measured object with a wider rib spacing, the measured object with a narrow rib spacing requires stronger penetration. Therefore, a lower elasticity is required to measure the ultrasonic frequency. In addition, the data characterizing the individual characteristics of the measured object may also include data characterizing the health status of the measured object. For example, a subject in poor health may require greater resolution. As an example, data characterizing the body shape, age, rib spacing, or health status of the tested object can be obtained by manual input, or the above data can also be automatically obtained from the information database or electronic medical record of the tested object.
当获取如上所述表征被测对象体型、年龄、肋间距或健康状况等能够通过文字或数字表示的数据时,可以直接将预先设定的与获取到的表征被测对象的个体特征的数据相关联的频率确定为所需的弹性测量超声频率。例如,当表征被测对象的个体特征的数据为表征被测对象体型的体重值时,若被测对象的体重值大于或等于预先设定的第一阈值,则可以为其选定较低的弹性测量超声频率,例如中心频率2.5MHz;当被测对象的体重低于第一阈值但不低于第二阈值时,为其选择中等的弹性测量超声频率,例如中心频率3.5MHz;当被测对象的体重低于第二阈值时,可以为其选定较高的弹性测量超声频率,例如中心频率5.0MHz。When obtaining data that can be expressed in words or numbers, such as the body shape, age, rib spacing, or health status of the measured object as described above, the preset can be directly related to the acquired data that characterizes the individual characteristics of the measured object The frequency of the coupling is determined as the ultrasonic frequency required for elasticity measurement. For example, when the data that characterizes the individual characteristics of the measured object is the weight value that characterizes the body shape of the measured object, if the weight value of the measured object is greater than or equal to the preset first threshold value, a lower value can be selected for it. Elasticity measurement ultrasonic frequency, such as the center frequency of 2.5MHz; when the weight of the measured object is lower than the first threshold but not lower than the second threshold, select a medium elasticity measurement ultrasonic frequency, such as the center frequency of 3.5MHz; When the subject's weight is lower than the second threshold, a higher elasticity measurement ultrasonic frequency can be selected for the subject, for example, the center frequency is 5.0 MHz.
在另一个实施例中,表征被测对象的个体特征的数据可以包括图像数据,例如所述被测对象的瞬时弹性测量的目标区域的超声图像数据,包括而不限于B型超声图像数据、M型超声图像数据或A型超声图像数据等常规超声图像数据。也就是说,在启动瞬时弹性测量之前,首先采集或获取目标区域的常规的超声图像数据,之后,还需要对超声图像数据进行进一步的分析,并根据从图像中提取的分析结果确定适用的弹性测量超声频率。In another embodiment, the data characterizing the individual characteristics of the measured object may include image data, for example, ultrasound image data of the target area of the instantaneous elasticity measurement of the measured object, including but not limited to B-mode ultrasound image data, M Conventional ultrasound image data such as type ultrasound image data or A type ultrasound image data. That is to say, before starting the instantaneous elasticity measurement, first collect or obtain the conventional ultrasound image data of the target area, and then further analyze the ultrasound image data, and determine the applicable elasticity according to the analysis results extracted from the image Measure the ultrasonic frequency.
作为一种实现方式,可以先连续采用多个超声频率分别发射超声波并接收回波,以采集被测对象的目标区域的超声图像数据。接着,对所述多个超声频率下的所述超声图像数据进行分析,并根据分析结果,将满足预定标准的超声图像数据所对应的超声频率作为所述弹性测量超声频率。其中,满足预定标准的超声图像可以是多个所述超声图像数据中分辨率和/或信噪比最佳的超声图像数据。As an implementation manner, a plurality of ultrasonic frequencies may be continuously used to transmit ultrasonic waves and receive echoes respectively, so as to collect ultrasonic image data of the target area of the measured object. Then, the ultrasound image data at the multiple ultrasound frequencies is analyzed, and according to the analysis result, the ultrasound frequency corresponding to the ultrasound image data that meets a predetermined standard is used as the elasticity measurement ultrasound frequency. Wherein, the ultrasound image that meets the predetermined standard may be ultrasound image data with the best resolution and/or signal-to-noise ratio among the multiple ultrasound image data.
在另一种实现方式中,也可以基于所获得的超声图像数据测量被测对象的个体特征参数,并根据测得的个体特征参数确定适用于被测对象的弹性测量超声频率。其中,当瞬时弹性测量的目标区域包括肝脏区域时,所述个体特征参数包括体表-肝包膜距离(Skin Capsule Distance,SCD)。一方面,体表 -肝包膜距离与人体体表脂肪含量和被测对象的体型相关,可以根据体表-肝包膜距离选择最优的弹性测量超声频率。当SCD较大时(例如,SCD>3.5cm),意味着当前被测对象的肝脏位置可能较深,需着重关注穿透力的需求,因而建议采用较低的弹性测量超声频率(例如2.5MHz)进行瞬时弹性测量。另一方面,一般弹性测量区域建议选择为肝脏包膜下方一定深度范围内,所以获得体表-肝包膜距离也有利于弹性测量区域的对应优化选择。SCD测量过程可以由用户手动进行,也可以由系统根据图像处理算法来自动测量,例如边界识别算法、图像分割算法等。In another implementation manner, it is also possible to measure the individual characteristic parameters of the measured object based on the obtained ultrasound image data, and determine the elasticity measurement ultrasonic frequency suitable for the measured object according to the measured individual characteristic parameters. Wherein, when the target area of the instantaneous elasticity measurement includes the liver area, the individual characteristic parameter includes the body surface-liver capsule distance (Skin Capsule Distance, SCD). On the one hand, the body surface-liver envelope distance is related to the body surface fat content and the body size of the measured object, and the optimal elasticity measurement ultrasound frequency can be selected according to the body surface-liver envelope distance. When the SCD is large (for example, SCD>3.5cm), it means that the liver of the current object may be deeper, and the need for penetrating power needs to be paid attention to. Therefore, it is recommended to use a lower elasticity to measure the ultrasonic frequency (for example, 2.5MHz) ) Perform instantaneous elasticity measurement. On the other hand, the general elasticity measurement area is recommended to be selected within a certain depth range below the liver capsule, so obtaining the body surface-liver capsule distance is also conducive to the corresponding optimal selection of the elasticity measurement area. The SCD measurement process can be performed manually by the user, or can be automatically measured by the system according to image processing algorithms, such as boundary recognition algorithms and image segmentation algorithms.
以上描述了确定被测对象的弹性测量超声频率的几种示例性的实现方式。在一个实施例中,确定适用于被测对象的弹性测量超声频率之后,超声成像系统可以直接将瞬时弹性测量的超声频率切换为步骤S310中所确定的弹性测量超声频率。在另一个实施例中,也可以通过图1所示的输出设备118输出建议采用所述弹性测量超声频率以进行瞬时弹性测量的提示信息,例如在显示器上输出可视化的提示信息,并根据接收到的用户指令确定是否将瞬时弹性测量过程中所述超声探头的发射和接收频率切换为所述弹性测量超声频率。The foregoing describes several exemplary implementations of determining the ultrasonic frequency of the elasticity measurement of the measured object. In one embodiment, after determining the elasticity measurement ultrasonic frequency suitable for the measured object, the ultrasonic imaging system may directly switch the ultrasonic frequency of the instantaneous elasticity measurement to the elasticity measurement ultrasonic frequency determined in step S310. In another embodiment, the output device 118 shown in FIG. 1 may also be used to output prompt information suggesting that the elasticity measurement ultrasonic frequency be used for instantaneous elasticity measurement, for example, output visual prompt information on the display, and according to the received The user instruction of determines whether to switch the transmitting and receiving frequencies of the ultrasonic probe during the instantaneous elasticity measurement process to the elasticity measurement ultrasonic frequency.
在采用不同频率进行超声波的发射接收时,用于计算弹性结果的回波信号的最佳深度位置也可能是不同的,所述弹性测量超声频率越低,所述感兴趣区域的深度越深,因而在一个实施例中,在确定弹性测量超声频率之后,还可以根据所述弹性测量超声频率确定用于获得瞬时弹性测量结果的感兴趣区域的深度范围。例如,当确定所述弹性测量超声频率时,可以自动在系统内预先设定的与该弹性测量超声频率相关联的深度范围内确定感兴趣区域,当切换频率时,感兴趣区域的深度范围也随之切换。感兴趣区域的深度范围的设定规则一般既要满足数据来源于感兴趣区域内部(例如在肝脏内部,而不能位于体表脂肪区域内部),同时具备比较高的信噪比。作为示例,当目标区域为肝脏区域时,当确定弹性测量超声频率为3.0MHz时,可以在25mm~65mm深度范围内确定感兴趣区域,而当确定弹性测量超声频率为2.5MHz时,可以在30mm~70mm深度范围内确定感兴趣区域。When using different frequencies for ultrasonic transmission and reception, the best depth position of the echo signal used to calculate the elasticity result may also be different. The lower the elasticity measurement ultrasonic frequency, the deeper the depth of the region of interest. Therefore, in one embodiment, after the elasticity measurement ultrasonic frequency is determined, the depth range of the region of interest for obtaining the instantaneous elasticity measurement result can also be determined according to the elasticity measurement ultrasonic frequency. For example, when the elasticity measurement ultrasonic frequency is determined, the region of interest can be automatically determined within the preset depth range associated with the elasticity measurement ultrasonic frequency in the system. When the frequency is switched, the depth range of the region of interest is also Switch accordingly. The rule for setting the depth range of the region of interest generally not only satisfies the data originating from the inside of the region of interest (for example, inside the liver, but not inside the fat area on the body surface), and at the same time has a relatively high signal-to-noise ratio. As an example, when the target area is the liver area, when the elasticity measurement ultrasonic frequency is determined to be 3.0MHz, the region of interest can be determined within the depth range of 25mm~65mm, and when the elasticity measurement ultrasonic frequency is determined to be 2.5MHz, it can be within 30mm. Determine the region of interest within the depth of ~70mm.
此外,如上所述,弹性测量的感兴趣区域一般选择为肝脏包膜下方一定深度范围内,因而若在此前确定弹性测量超声频率时确定了被测对象的体表-肝包膜距离,则还可以根据所述体表-肝包膜距离确定用于获得所述瞬时弹性 测量结果的感兴趣区域的深度范围。In addition, as mentioned above, the region of interest for elasticity measurement is generally selected to be within a certain depth below the liver capsule. Therefore, if the distance between the body surface and liver capsule of the measured object is determined when the elasticity measurement ultrasound frequency is determined before, it is still The depth range of the region of interest for obtaining the instantaneous elasticity measurement result can be determined according to the body surface-liver envelope distance.
当然,瞬时弹性测量的感兴趣区域也可以由用户根据显示图像的清晰度和穿透深度等自行判断,超声成像系统根据用户输入确定用于获得所述瞬时弹性测量结果的感兴趣区域的深度范围。具体地,可以在显示器上显示超声图像,由用户来手动选择超声图像上的感兴趣区域,并根据接收到的用户输入来获取用户选择的感兴趣区域。在其他示例中,还可以通过半自动的方式来获取感兴趣区域,例如,首先根据弹性测量超声频率自动确定一个大致的深度范围,再由用户在该深度范围内手动选择更为精确的感兴趣区域。Of course, the region of interest for instantaneous elasticity measurement can also be determined by the user based on the clarity and penetration depth of the displayed image. The ultrasound imaging system determines the depth range of the region of interest for obtaining the instantaneous elasticity measurement result according to user input. . Specifically, the ultrasound image can be displayed on the display, the user manually selects the region of interest on the ultrasound image, and the region of interest selected by the user is obtained according to the received user input. In other examples, the region of interest can also be obtained in a semi-automatic manner. For example, first an approximate depth range is automatically determined according to the elasticity measurement ultrasonic frequency, and then the user manually selects a more accurate region of interest within the depth range .
在步骤S320,对所述被测对象施加机械振动,以在所述被测对象的目标区域内产生剪切波。In step S320, mechanical vibration is applied to the measured object to generate a shear wave in the target area of the measured object.
在本实施例中,以振动器设置在超声探头内部为例来进行描述,但应理解,振动器还可以与超声探头相互独立。当超声探头本身包括振动器时,可以向超声探头的振动器输出用于驱动振动器振动的驱动信号以实施瞬时弹性测量,振动器接收到驱动信号以后产生机械振动,从而使与被测对象体表接触的超声探头振动,并通过超声探头将振动产生的剪切波传送至被测对象目标区域的组织中,以在目标区域的组织内部生成剪切波,该剪切波行经选定的感兴趣区域。In this embodiment, the vibrator is provided inside the ultrasonic probe as an example for description, but it should be understood that the vibrator can also be independent of the ultrasonic probe. When the ultrasonic probe itself includes a vibrator, a driving signal for driving the vibrator to vibrate can be output to the vibrator of the ultrasonic probe to implement instantaneous elasticity measurement. The ultrasonic probe in contact with the surface vibrates, and the shear wave generated by the vibration is transmitted to the tissue in the target area of the measured object through the ultrasonic probe to generate a shear wave inside the tissue in the target area. The shear wave travels through the selected sensory area. Area of interest.
在一个实施例中,由于不同的被测对象适用于不同的机械振动振幅,因此,瞬时弹性测量方法300还可以包括:确定适用于所述被测对象的机械振动振幅,以及根据所述机械振动振幅确定所述机械振动的驱动强度,以所确定的驱动强度驱动振动器以产生满足要求的机械振动振幅。In an embodiment, since different measured objects are suitable for different mechanical vibration amplitudes, the instantaneous elasticity measurement method 300 may further include: determining the mechanical vibration amplitudes suitable for the measured object, and according to the mechanical vibration The amplitude determines the driving intensity of the mechanical vibration, and the vibrator is driven with the determined driving intensity to generate a mechanical vibration amplitude that meets the requirements.
其中,机械振动振幅的确定与剪切波的穿透力和被测对象的承受力有关。因此,可以基于所述被测对象的体型、年龄、肋间距和/或健康状况等确定机械振动振幅。例如,大体型的被测对象或肋间距窄的被测对象需要较强的穿透力,因而适用于较大的机械振动振幅;幼年或健康状况较差的被测对象承受能力较差,因而适用于较小的机械振动振幅。Among them, the determination of the mechanical vibration amplitude is related to the penetration force of the shear wave and the endurance of the measured object. Therefore, the mechanical vibration amplitude can be determined based on the body shape, age, rib spacing, and/or health status of the measured object. For example, a large-sized test object or a test object with a narrow rib spacing requires stronger penetrating power, so it is suitable for larger mechanical vibration amplitudes; young or poorly-healthy test objects have poor bearing capacity, so Suitable for small mechanical vibration amplitude.
在一个实施例中,机械振动振幅的确定还可以与弹性测量超声频率的确定相关联。例如,选定弹性测量超声频率以后,自动确定预先设定的与之关联的机械振动振幅。In one embodiment, the determination of the mechanical vibration amplitude may also be associated with the determination of the elastic measurement ultrasonic frequency. For example, after selecting the elastic measurement ultrasonic frequency, the preset mechanical vibration amplitude associated with it is automatically determined.
在步骤S330,通过包括多个阵元的超声探头,采用所述弹性测量超声频率向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超 声回波,以获得超声回波数据。In step S330, an ultrasonic probe including a plurality of array elements is used to transmit ultrasonic waves tracking the shear wave to the target area using the elasticity measurement ultrasonic frequency, and receive ultrasonic echoes of the target area to obtain ultrasonic waves. Echo data.
其中,可以采用图1所示的超声成像系统100中的处理器116控制发射/接收电路114激励超声探头110以步骤S310中确定的弹性测量超声频率向被测对象的目标区域发射超声波,以跟踪在所述目标区域内传播的剪切波,以及接收从目标区域返回的所述超声波的超声回波以获得超声回波数据。由于本申请实施例采用多阵元的超声探头,在较宽的频带下都具有较佳的灵敏度,因而可以基于同一把探头根据需要切换频率,在提高测量准确性的同时,无需切换探头,避免了繁琐的操作。相对于传统的瞬时弹性测量的超声探头,本申请实施例的超声探头由于采用了多阵元,其产生的超声波频率范围较宽,相较于传统瞬时弹性测量的超声探头,本申请包括多阵元的超声探头也可以认为是一种宽频探头。The processor 116 in the ultrasonic imaging system 100 shown in FIG. 1 may be used to control the transmitting/receiving circuit 114 to excite the ultrasonic probe 110 to transmit ultrasonic waves to the target area of the object to be measured at the elasticity measurement ultrasonic frequency determined in step S310 to track Shear waves propagated in the target area, and ultrasonic echoes of the ultrasonic waves returned from the target area are received to obtain ultrasonic echo data. Since the embodiment of this application adopts a multi-element ultrasonic probe with better sensitivity in a wider frequency band, it can switch the frequency as needed based on the same probe, which improves the measurement accuracy and does not need to switch the probe to avoid A tedious operation. Compared with the traditional ultrasonic probe for instantaneous elasticity measurement, the ultrasonic probe of the embodiment of the present application adopts multiple array elements, and the ultrasonic wave generated by it has a wider frequency range. Compared with the traditional ultrasonic probe for instantaneous elasticity measurement, the present application includes multiple arrays. Yuan's ultrasound probe can also be considered as a broadband probe.
在本步骤中,向目标区域施加机械振动并产生剪切波后,发射作为追踪脉冲的超声波并接收其超声回波,从而得到目标区域内一段时间内一段传播范围内的追踪脉冲的回波数据。发射超声波的发射间隔时间可预先确定。所述超声回波数据记录了剪切波传播过程中,其传播范围内各位置上的组织信息。In this step, after mechanical vibration is applied to the target area and shear waves are generated, ultrasonic waves are emitted as tracking pulses and received ultrasonic echoes, so as to obtain echo data of tracking pulses within a propagation range within a period of time in the target area . The transmission interval time for transmitting ultrasonic waves can be predetermined. The ultrasonic echo data records the tissue information at each position within the propagation range of the shear wave during the propagation process.
步骤S340,根据所述超声回波数据获得所述目标区域的瞬时弹性测量结果。Step S340: Obtain an instantaneous elasticity measurement result of the target area according to the ultrasonic echo data.
其中,所述瞬时弹性测量结果包括用于评价目标区域组织的弹性程度的弹性参数,其可以是剪切波的传播速度,也可以是弹性模量。Wherein, the instantaneous elasticity measurement result includes an elasticity parameter used to evaluate the elasticity of the tissue in the target area, which may be the propagation velocity of the shear wave or the elastic modulus.
具体地,在接收到超声回波数据以后,可以对超声回波数据进行处理,例如滤波、放大、波束合成等处理。之后,可以基于处理后的超声回波数据,采用相关算法得到所需要的瞬时弹性测量参数或图像。在本申请实施例中,可以根据超声回波数据进行形变估计运算,形成目标区域内各检测位置处对应的形变-时间曲线,其反映了该点处组织形变值随时间变化的关系。根据形变-时间曲线中峰值对应时间值和检测位置物理距离值,可以作出拟合时间-距离直线,求取时间-距离直线的斜率的倒数,即可得到剪切波速度值,之后可以通过剪切波速度计算反映组织硬度的弹性模量参数。可以理解的是,以上计算过程仅是示例性的,本申请实施例可以采用其他合适的算法根据超声回波数据获得瞬时弹性测量结果。Specifically, after receiving the ultrasonic echo data, the ultrasonic echo data can be processed, such as filtering, amplifying, and beam synthesis. After that, based on the processed ultrasonic echo data, relevant algorithms can be used to obtain the required instantaneous elasticity measurement parameters or images. In the embodiment of the present application, the deformation estimation operation can be performed based on the ultrasonic echo data to form a corresponding deformation-time curve at each detection position in the target area, which reflects the relationship between the tissue deformation value at that point and time. According to the corresponding time value of the peak value in the deformation-time curve and the physical distance value of the detection position, a fitting time-distance straight line can be made, and the reciprocal of the slope of the time-distance straight line can be obtained to obtain the shear wave velocity value. The shear wave velocity calculates the elastic modulus parameter that reflects the hardness of the tissue. It can be understood that the above calculation process is only exemplary, and other suitable algorithms may be used in the embodiment of the present application to obtain the instantaneous elasticity measurement result based on the ultrasonic echo data.
在一些实施例中,在计算出瞬时弹性测量结果后,可以直接将计算出的 瞬时弹性测量结果通过输出设备(例如图1所示的输出设备118)进行输出。其中,所述输出设备可以是显示装置,例如显示屏或显示器等等,瞬时弹性测量结果可以在显示装置的显示界面上进行显示,例如,可以以文字方式显示剪切波速度、弹性模量等参数,还可以显示出组织弹性图像。In some embodiments, after the instantaneous elasticity measurement result is calculated, the calculated instantaneous elasticity measurement result can be directly output through an output device (for example, the output device 118 shown in FIG. 1). Wherein, the output device may be a display device, such as a display screen or a display, etc. The instantaneous elasticity measurement result may be displayed on the display interface of the display device, for example, the shear wave velocity, elastic modulus, etc. may be displayed in text Parameters can also display tissue elasticity images.
现在重新参照图1,本申请实施例还提供了一种超声成像系统100,超声成像系统100可以用于实现上述方法300。超声成像系统100可以包括超声探头110、振动器112、发射/接收电路114、处理器116和输出设备118等部件,其中,超声探头110包括多个阵元(即换能器阵元),因而能够在较宽频带下发射和接收超声波;振动器112用于对被测对象施加机械振动,以在所述被测对象的目标区域内产生剪切波;发射/接收电路114用于激励所述超声探头110采用适用于所述被测对象的弹性测量超声频率向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超声回波,以获得超声回波数据;处理器116用于确定所述弹性测量超声频率,以及对所述超声回波数据进行处理,以获得所述目标区域的瞬时弹性测量结果;输出设备118用于输出所述瞬时弹性测量结果。Referring now to FIG. 1 again, an embodiment of the present application also provides an ultrasound imaging system 100, which can be used to implement the above-mentioned method 300. The ultrasound imaging system 100 may include components such as an ultrasound probe 110, a vibrator 112, a transmitting/receiving circuit 114, a processor 116, and an output device 118. Among them, the ultrasound probe 110 includes multiple array elements (ie, transducer array elements). It can transmit and receive ultrasonic waves in a wider frequency band; the vibrator 112 is used to apply mechanical vibration to the measured object to generate shear waves in the target area of the measured object; the transmitting/receiving circuit 114 is used to excite the The ultrasonic probe 110 uses an elasticity measurement ultrasonic frequency suitable for the measured object to transmit an ultrasonic wave tracking the shear wave to the target area, and receives the ultrasonic echo of the target area to obtain ultrasonic echo data; processing; The device 116 is used to determine the elasticity measurement ultrasonic frequency and process the ultrasonic echo data to obtain the instantaneous elasticity measurement result of the target area; the output device 118 is used to output the instantaneous elasticity measurement result.
在一个实施例中,所述输出设备118还用于输出建议采用所述弹性测量超声频率以进行瞬时弹性测量的提示信息,处理器116还用于根据接收到的用户指令确定是否将所述超声探头110的发射和接收频率切换为所述弹性测量超声频率。In one embodiment, the output device 118 is also used to output prompt information suggesting that the elasticity measurement ultrasonic frequency is used for instantaneous elasticity measurement, and the processor 116 is also used to determine whether to use the ultrasonic The transmitting and receiving frequencies of the probe 110 are switched to the elastic measurement ultrasonic frequency.
以上仅对超声成像系统100的主要部件和各部件的主要功能进行了描述,而省略了以上已经描述过的细节内容。各个部件的其他相关描述可以参照上文对超声成像系统100和瞬时弹性测量方法300的具体描述。Only the main components of the ultrasound imaging system 100 and the main functions of each component are described above, and the details that have been described above are omitted. For other related descriptions of the various components, reference may be made to the detailed description of the ultrasound imaging system 100 and the instantaneous elasticity measurement method 300 above.
基于以上描述,根据本申请实施例的瞬时弹性测量方法和超声成像系统,通过使用包括多个阵元的超声探头,可以在不切换探头的情况下,根据被测对象的实际需要选择不同的弹性测量超声频率,从而满足临床中对不同的穿透力和分辨率的检测需求,提升了弹性测量的有效性,同时操作简便,并且有利于节约成本。Based on the above description, according to the instantaneous elasticity measurement method and the ultrasonic imaging system of the embodiments of the present application, by using an ultrasonic probe including multiple array elements, different elasticities can be selected according to the actual needs of the measured object without switching the probe. The ultrasonic frequency is measured, so as to meet the needs of different penetrating power and resolution in the clinic, improve the effectiveness of elasticity measurement, and at the same time, it is easy to operate and is beneficial to cost saving.
在瞬时弹性的成像过程中,除了得到目标组织的与弹性相关的结果以外,还可以进行声衰减参数的成像或测量。声衰减参数用于反映超声波在一定深度范围内传播时的声强度(或幅度、能量)的衰减程度,在临床中可用于脂肪肝程度的预测。一般来说,脂肪肝程度越严重,声衰减越快。如图4所示, 对于同一频率的超声波来说,超声波的幅度与传播深度成线性反比关系,声衰减参数通常对应于上述反比关系的斜率。本发明另一实施例提供了一种声衰减参数的测量方法,通过使用包括多个阵元的超声探头,可以为不同的被测对象选择相对合适的声衰减参数测量频率进行声衰减参数的测量,提升测量的准确性。In the instantaneous elastic imaging process, in addition to obtaining the elasticity-related results of the target tissue, imaging or measurement of acoustic attenuation parameters can also be performed. The sound attenuation parameter is used to reflect the attenuation degree of the sound intensity (or amplitude, energy) when the ultrasonic wave propagates in a certain depth range, and can be used to predict the degree of fatty liver in clinical practice. Generally speaking, the more serious the degree of fatty liver, the faster the sound attenuation. As shown in Fig. 4, for ultrasonic waves of the same frequency, the amplitude of the ultrasonic waves has a linear inverse relationship with the propagation depth, and the sound attenuation parameter usually corresponds to the slope of the above inverse relationship. Another embodiment of the present invention provides a method for measuring sound attenuation parameters. By using an ultrasonic probe that includes multiple array elements, a relatively appropriate sound attenuation parameter measurement frequency can be selected for different objects to be measured for sound attenuation parameter measurement. , Improve the accuracy of measurement.
图5是本申请实施例的声衰减参数测量方法500的一个示意性流程图。如图5所示,所述方法500包括如下步骤:FIG. 5 is a schematic flowchart of a method 500 for measuring sound attenuation parameters according to an embodiment of the present application. As shown in FIG. 5, the method 500 includes the following steps:
步骤S510,确定适用于被测对象的声衰减参数测量频率。Step S510: Determine the sound attenuation parameter measurement frequency suitable for the measured object.
其中,确定适用于被测对象的声衰减参数测量频率类似于方法300中确定被测对象的弹性测量超声频率的方式。作为一种实现方式,声衰减参数的测量过程可以与瞬时弹性测量过程同步进行,即复用瞬时弹性成像的回波数据。具体地,在进行瞬时弹性测量的过程中,处理器在获取到追踪剪切波的超声波的超声回波数据后,还可以进一步根据该回波数据来确定目标区域的声衰减参数。在该实现方式中,声衰减参数测量频率等同于上述的弹性测量超声频率。在其他实现方式中,声衰减参数测量也可以与瞬时弹性测量分别进行,则声衰减参数测量频率可以与弹性测量超声频率相同,也可以不同于弹性测量超声频率。Wherein, determining the sound attenuation parameter measurement frequency suitable for the measured object is similar to the method 300 for determining the elastic measurement ultrasonic frequency of the measured object. As an implementation manner, the measurement process of the acoustic attenuation parameter can be performed synchronously with the instantaneous elasticity measurement process, that is, the echo data of the instantaneous elastography is multiplexed. Specifically, in the process of instantaneous elasticity measurement, after acquiring the ultrasonic echo data of the ultrasonic wave tracking the shear wave, the processor may further determine the acoustic attenuation parameter of the target area according to the echo data. In this implementation, the sound attenuation parameter measurement frequency is equivalent to the elastic measurement ultrasonic frequency described above. In other implementations, the sound attenuation parameter measurement can also be performed separately from the instantaneous elasticity measurement, and the sound attenuation parameter measurement frequency can be the same as the elasticity measurement ultrasonic frequency, or it can be different from the elasticity measurement ultrasonic frequency.
具体地,所述声衰减参数测量频率指用于声衰减参数测量的超声发射和接收频率,进一步地,该声衰减参数测量频率可以是超声发射和接收的中心频率。声衰减参数测量频率越高,则分辨率越高而穿透力越低,反之,声衰减参数测量频率越低,则分辨率越低而穿透力越高。因此,确定适用于被测对象的声衰减参数测量频率有利于在超声穿透力和空间分辨率之间达到较优化的平衡,提高声衰减参数测量的有效性和准确性。Specifically, the sound attenuation parameter measurement frequency refers to the ultrasonic transmitting and receiving frequencies used for sound attenuation parameter measurement. Further, the sound attenuation parameter measurement frequency may be the center frequency of ultrasonic transmitting and receiving. The higher the sound attenuation parameter measurement frequency, the higher the resolution and the lower the penetration power. Conversely, the lower the sound attenuation parameter measurement frequency, the lower the resolution and the higher the penetration power. Therefore, determining the sound attenuation parameter measurement frequency suitable for the measured object is conducive to achieving a more optimized balance between ultrasonic penetration and spatial resolution, and improving the effectiveness and accuracy of sound attenuation parameter measurement.
作为具体的实施方式,可以首先获取表征被测对象的个体特征的数据,并根据表征所述被测对象的个体特征的数据确定适用于该被测对象的声衰减参数测量频率。其中,表征被测对象的个体特征的数据可以是表征被测对象身体结构特征的数据。在根据表征被测对象的个体特征的数据确定对其适用的声衰减参数测量频率时,针对不同的数据,可以直接匹配到与所获得的数据关联的声衰减参数测量频率,也可以对所获得的数据进行分析,并根据分析结果选择适用的声衰减参数测量频率。As a specific implementation manner, the data characterizing the individual characteristics of the measured object may be acquired first, and the sound attenuation parameter measurement frequency suitable for the measured object can be determined according to the data characterizing the individual characteristics of the measured object. Among them, the data that characterizes the individual characteristics of the measured object may be data that characterizes the physical structure of the measured object. When determining the sound attenuation parameter measurement frequency applicable to the measured object according to the data that characterizes the individual characteristics of the measured object, for different data, it can be directly matched to the sound attenuation parameter measurement frequency associated with the obtained data, or the obtained sound attenuation parameter measurement frequency can be directly matched. Analyze the data, and select the applicable sound attenuation parameter measurement frequency according to the analysis result.
在一个示例中,表征被测对象的个体特征的数据可以包括表征被测对象 的体型的数据,例如体重、胸围或腰围等。体型越大,所需的穿透力越高,则声衰减参数测量频率越低。类似地,表征被测对象的个体特征的数据可以包括被测对象的年龄、肋间距或健康状况的数据。当获取如上所述表征被测对象体型、年龄、肋间距或健康状况等能够通过文字或数字表示的数据时,可以直接将预先设定的与获取到的表征被测对象的个体特征的数据相关联的频率确定为所需的声衰减参数测量频率。In an example, the data characterizing the individual characteristics of the measured object may include data characterizing the body type of the measured object, such as weight, chest circumference, or waist circumference. The larger the body size, the higher the penetration force required, and the lower the sound attenuation parameter measurement frequency. Similarly, the data characterizing the individual characteristics of the measured object may include data on the age, rib spacing, or health status of the measured object. When obtaining data that can be expressed in words or numbers, such as the body shape, age, rib spacing, or health status of the measured object as described above, the preset can be directly related to the acquired data that characterizes the individual characteristics of the measured object The frequency of the connection is determined as the measurement frequency of the required sound attenuation parameter.
在另一个实施例中,表征被测对象的个体特征的数据可以包括图像数据,例如所述被测对象的声衰减参数测量的目标区域的超声图像数据。当采用超声图像数据确定声衰减参数测量频率时,还需要对超声图像数据进行进一步的分析,并根据从图像中提取的分析结果确定适用的声衰减参数测量频率。作为一种实现方式,可以先连续采用多个超声频率分别发射超声波并接收回波,以采集被测对象的目标区域的超声图像数据。接着,对所述多个超声频率下的所述超声图像数据进行分析,并根据分析结果,将满足预定标准的超声图像数据所对应的超声频率作为所述声衰减参数测量频率。其中,满足预定标准的超声图像可以是多个所述超声图像数据中分辨率和/或信噪比最佳的超声图像数据。In another embodiment, the data characterizing the individual characteristics of the measured object may include image data, for example, ultrasound image data of the target area of the measurement of the acoustic attenuation parameter of the measured object. When the ultrasonic image data is used to determine the sound attenuation parameter measurement frequency, it is necessary to further analyze the ultrasonic image data, and determine the applicable sound attenuation parameter measurement frequency according to the analysis result extracted from the image. As an implementation manner, a plurality of ultrasonic frequencies may be continuously used to transmit ultrasonic waves and receive echoes respectively, so as to collect ultrasonic image data of the target area of the measured object. Then, the ultrasound image data at the multiple ultrasound frequencies is analyzed, and according to the analysis result, the ultrasound frequency corresponding to the ultrasound image data meeting a predetermined standard is used as the sound attenuation parameter measurement frequency. Wherein, the ultrasound image that meets the predetermined standard may be ultrasound image data with the best resolution and/or signal-to-noise ratio among the multiple ultrasound image data.
在另一种实现方式中,也可以基于所获得的超声图像数据测量被测对象的个体特征参数,并根据测得的个体特征参数确定适用于被测对象的声衰减参数测量频率。其中,当声衰减参数测量的目标区域包括肝脏区域时,所述个体特征参数包括体表-肝包膜距离(Skin Capsule Distance,SCD)。In another implementation manner, it is also possible to measure the individual characteristic parameters of the measured object based on the obtained ultrasound image data, and determine the sound attenuation parameter measurement frequency suitable for the measured object according to the measured individual characteristic parameters. Wherein, when the target area of the sound attenuation parameter measurement includes the liver area, the individual characteristic parameter includes the body surface-liver capsule distance (Skin Capsule Distance, SCD).
以上描述了确定被测对象的声衰减参数测量频率的几种示例性的实现方式。在一个实施例中,确定适用于被测对象的声衰减参数测量频率之后,超声成像系统可以直接将声衰减参数测量频率切换为步骤S510中所确定的声衰减参数测量频率。在另一个实施例中,也可以输出建议采用所述声衰减参数测量频率以进行声衰减参数测量的提示信息,并根据接收到的用户指令确定是否将声衰减参数测量过程中所述超声探头的发射和接收频率切换为所述声衰减参数测量频率。The foregoing describes several exemplary implementations of determining the measurement frequency of the sound attenuation parameter of the measured object. In one embodiment, after determining the sound attenuation parameter measurement frequency suitable for the measured object, the ultrasound imaging system may directly switch the sound attenuation parameter measurement frequency to the sound attenuation parameter measurement frequency determined in step S510. In another embodiment, a prompt message suggesting that the sound attenuation parameter measurement frequency should be used for sound attenuation parameter measurement can also be output, and according to the received user instruction, it is determined whether to change the sound attenuation parameter measurement process of the ultrasonic probe. The transmitting and receiving frequencies are switched to the sound attenuation parameter measurement frequency.
步骤S520,通过包括多个阵元的超声探头,采用所述声衰减参数测量频率向所述被测对象的目标区域发射超声波,并接收所述目标区域的超声回波,以获得超声回波数据。Step S520, using the acoustic attenuation parameter measurement frequency to transmit ultrasonic waves to the target area of the measured object through an ultrasonic probe including a plurality of array elements, and receive ultrasonic echoes of the target area to obtain ultrasonic echo data .
其中,可以采用超声成像系统的处理器控制发射/接收电路激励超声探头 以步骤S510中确定的声衰减参数测量频率向被测对象的目标区域发射超声波,以及接收从目标区域返回的所述超声波的超声回波以获得超声回波数据。由于本申请实施例采用多阵元的超声探头,在较宽的频带下都具有较佳的灵敏度,因而可以基于同一把探头根据需要切换频率,在提高测量准确性的同时,无需切换探头,避免了繁琐的操作。Wherein, the processor of the ultrasound imaging system may be used to control the transmitting/receiving circuit to excite the ultrasonic probe to transmit ultrasonic waves to the target area of the measured object at the sound attenuation parameter measurement frequency determined in step S510, and to receive the ultrasonic waves returned from the target area. Ultrasound echo to obtain ultrasonic echo data. Since the embodiment of this application adopts a multi-element ultrasonic probe with better sensitivity in a wider frequency band, it can switch the frequency as needed based on the same probe, which improves the measurement accuracy and does not need to switch the probe to avoid A tedious operation.
步骤S530,根据所述超声回波数据获得所述目标区域的声衰减参数测量结果。Step S530: Obtain the sound attenuation parameter measurement result of the target area according to the ultrasonic echo data.
其中,可以根据目标区域对应的超声回波信号在各个深度的幅度,确定目标区域的声衰减参数。通常,从不同深度返回的超声回波信号的幅度不同,深度即目标区域中的组织与探头的距离,深度越深的组织得到的超声回波信号的幅度通常也越低,参见图4。由于超声回波信号的幅度随着深度的增加而降低,将幅度转换为dB(分贝)为单位时,即可确定幅度随着深度的增加而呈现降低的趋势,超声回波的能量衰减的斜率即可理解为声衰减参数。Among them, the acoustic attenuation parameter of the target area can be determined according to the amplitude of the ultrasonic echo signal corresponding to the target area at each depth. Generally, the amplitudes of the ultrasonic echo signals returned from different depths are different. The depth refers to the distance between the tissue in the target area and the probe. The deeper the tissue, the lower the amplitude of the ultrasonic echo signals, see Figure 4. Since the amplitude of the ultrasonic echo signal decreases with the increase of depth, when the amplitude is converted into dB (decibel) as a unit, it can be determined that the amplitude will decrease with the increase of depth. The slope of the energy attenuation of ultrasonic echo It can be understood as a sound attenuation parameter.
最后,还可以通过输出设备输出声衰减参数测量结果,例如在显示装置上显示声衰减参数测量结果。所述测量结果可以包括声衰减参数的数值、曲线,此外,还可以根据该声衰减参数确定每个像素点的像素值,得到声衰减图像;声衰减图像可以与基础超声图像或弹性图像叠加显示。Finally, the sound attenuation parameter measurement result can also be output through the output device, for example, the sound attenuation parameter measurement result is displayed on the display device. The measurement result can include the value and curve of the sound attenuation parameter. In addition, the pixel value of each pixel can be determined according to the sound attenuation parameter to obtain the sound attenuation image; the sound attenuation image can be superimposed and displayed with the basic ultrasound image or elastic image .
参照图6,本申请实施例还提供了一种超声成像系统600,超声成像系统600可以用于实现上述方法500。超声成像系统600可以包括超声探头610、发射/接收电路612、处理器614和输出设备618等部件。其中,超声探头610、发射/接收电路612、处理器614和输出设备618的具体细节可以参照图1所示的超声成像系统100中的超声探头110、发射/接收电路114、处理器116和输出设备118,以下仅对超声成像系统600的主要部件和各部件的主要功能进行了描述,而省略了以上已经描述过的细节内容。各个部件的其他相关描述可以参照上文对超声成像系统100和声衰减参数测量方法600的具体描述。Referring to FIG. 6, an embodiment of the present application also provides an ultrasound imaging system 600, and the ultrasound imaging system 600 may be used to implement the above method 500. The ultrasound imaging system 600 may include components such as an ultrasound probe 610, a transmitting/receiving circuit 612, a processor 614, and an output device 618. Among them, the specific details of the ultrasonic probe 610, the transmitting/receiving circuit 612, the processor 614, and the output device 618 can refer to the ultrasonic probe 110, the transmitting/receiving circuit 114, the processor 116, and the output device in the ultrasonic imaging system 100 shown in FIG. For the device 118, only the main components of the ultrasound imaging system 600 and the main functions of each component are described below, and the details that have been described above are omitted. For other related descriptions of the various components, reference may be made to the detailed description of the ultrasound imaging system 100 and the sound attenuation parameter measurement method 600 above.
在本实施例中,超声成像系统600可以实现为瞬时弹性超声成像系统,则该超声成像系统600可以包括振动器,用于对被测对象的目标区域施加机械振动以产生剪切波,从而启动瞬时弹性测量,具体参见超声成像系统100中的振动器112。或者,超声成像系统600也可以实现为声辐射力弹性成像系统,则超声成像系统600可以不包括振动器,由超声探头610对被测对象 的目标区域施加声辐射力脉冲以产生剪切波,从而启动声辐射力弹性测量。In this embodiment, the ultrasound imaging system 600 may be implemented as a transient elastic ultrasound imaging system, and the ultrasound imaging system 600 may include a vibrator for applying mechanical vibration to the target area of the measured object to generate shear waves, thereby starting For the instantaneous elasticity measurement, refer to the vibrator 112 in the ultrasound imaging system 100 for details. Alternatively, the ultrasound imaging system 600 can also be implemented as an acoustic radiation force elastic imaging system. The ultrasound imaging system 600 may not include a vibrator. The ultrasound probe 610 applies acoustic radiation force pulses to the target area of the object to be measured to generate shear waves. This starts the elastic measurement of acoustic radiation force.
在超声成像系统600中,超声探头110包括多个阵元(即换能器阵元),因而能够在较宽频带下发射和接收超声波;发射/接收电路612用于激励所述超声探头610采用适用于所述被测对象的声衰减参数频率向被测对象的目标区域发射超声波,并接收所述目标区域的超声回波,以获得超声回波数据;处理器614用于确定所述声衰减参数测量频率,以及对所述超声回波数据进行处理,以获得所述目标区域的声衰减参数测量结果;输出设备618用于输出所述声衰减参数测量结果。In the ultrasound imaging system 600, the ultrasound probe 110 includes multiple array elements (ie, transducer array elements), so that it can transmit and receive ultrasound in a wider frequency band; the transmitting/receiving circuit 612 is used to excite the ultrasound probe 610 to use The acoustic attenuation parameter frequency applicable to the measured object transmits ultrasonic waves to the target area of the measured object, and receives the ultrasonic echo of the target area to obtain ultrasonic echo data; the processor 614 is used to determine the acoustic attenuation Parameter measurement frequency, and processing the ultrasonic echo data to obtain the sound attenuation parameter measurement result of the target area; the output device 618 is used to output the sound attenuation parameter measurement result.
基于以上描述,根据本申请实施例的声衰减参数测量方法和超声成像系统,通过使用包括多个阵元的超声探头,可以在不切换探头的情况下,根据被测对象的实际需要选择不同的声衰减参数测量超声频率,从而满足临床中对不同的穿透力和分辨率的检测需求,提升了声衰减参数测量的有效性,同时操作简便,并且有利于节约成本。Based on the above description, according to the sound attenuation parameter measurement method and ultrasonic imaging system of the embodiments of the present application, by using an ultrasonic probe including multiple array elements, different probes can be selected according to the actual needs of the measured object without switching the probe. The sound attenuation parameter measures the ultrasonic frequency, so as to meet the detection requirements of different penetration and resolution in the clinic, improve the effectiveness of the sound attenuation parameter measurement, and at the same time, it is easy to operate and is beneficial to cost saving.
本申请另一实施例还提供一种弹性测量方法,其基于包括多个阵元的超声探头,采用多个弹性测量超声频率进行弹性测量,并综合多次测量的结果以得到更为准确的综合测量结果。下面,将参考图7描述根据本申请一个实施例的弹性测量方法。图7是本申请实施例的弹性测量方法700的一个示意性流程图。Another embodiment of the present application also provides an elasticity measurement method, which is based on an ultrasonic probe including multiple array elements, uses multiple elasticity measurement ultrasonic frequencies to perform elasticity measurement, and integrates the results of multiple measurements to obtain a more accurate synthesis. Measurement results. Hereinafter, the elasticity measurement method according to an embodiment of the present application will be described with reference to FIG. 7. FIG. 7 is a schematic flowchart of an elasticity measurement method 700 according to an embodiment of the present application.
如图7所示,所述弹性测量方法700包括如下步骤:As shown in FIG. 7, the elasticity measurement method 700 includes the following steps:
在步骤S710,基于包括多个阵元的超声探头,依次采用至少两个弹性测量超声频率向被测对象的目标区域发射跟踪剪切波的超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;In step S710, based on the ultrasonic probe including a plurality of array elements, at least two elastic measuring ultrasonic frequencies are successively used to transmit ultrasonic waves that track shear waves to the target area of the object to be measured, and receive ultrasonic echoes of the target area to Obtain at least two sets of ultrasonic echo data;
在步骤S720,根据所述超声回波数据获得每个所述超声频率下的所述目标区域的弹性测量结果;In step S720, obtain the elasticity measurement result of the target area at each ultrasonic frequency according to the ultrasonic echo data;
在步骤S730,综合至少两个所述弹性测量结果,以确定综合弹性测量结果。In step S730, at least two of the elasticity measurement results are integrated to determine a comprehensive elasticity measurement result.
在一个实施例中,弹性测量方法700可以是一种瞬时弹性测量方法,即首先基于机械振动在所述被测对象的所述目标区域产生所述剪切波。在另一个实施例中,弹性测量方法700也可以是一种声辐射力弹性测量方法,即基于声辐射力在所述被测对象的所述目标区域产生所述剪切波。In an embodiment, the elasticity measurement method 700 may be an instantaneous elasticity measurement method, that is, the shear wave is first generated in the target area of the measured object based on mechanical vibration. In another embodiment, the elasticity measurement method 700 may also be an acoustic radiation force elasticity measurement method, that is, the shear wave is generated in the target area of the measured object based on the acoustic radiation force.
在本实施例中,由超声探头以至少两个弹性测量超声频率依次向被测对 象的目标区域发射超声波,以跟踪在所述目标区域内传播的剪切波,以及接收从目标区域返回的所述超声波的超声回波以获得超声回波数据。作为示例,剪切波的产生和超声波的发射与接收交替进行。由于本申请实施例采用多阵元的超声探头,在较宽的频带下都具有较佳的灵敏度,因而可以基于同一把探头根据需要切换频率,在提高测量准确性的同时,无需切换探头,避免了繁琐的操作。In this embodiment, the ultrasonic probe emits ultrasonic waves to the target area of the object to be measured with at least two elasticity measuring ultrasonic frequencies in order to track the shear waves propagating in the target area, and to receive all the returning from the target area. The ultrasonic echo of the ultrasonic wave is used to obtain ultrasonic echo data. As an example, the generation of shear waves and the transmission and reception of ultrasonic waves alternate. Since the embodiment of this application adopts a multi-element ultrasonic probe with better sensitivity in a wider frequency band, it can switch the frequency as needed based on the same probe, which improves the measurement accuracy and does not need to switch the probe to avoid A tedious operation.
之后,基于每组超声回波数据,获得一个弹性测量结果。其中,所述弹性测量结果包括用于评价目标区域组织的弹性程度的弹性参数,其可以是剪切波的传播速度,也可以是弹性模量。具体地,在接收到超声回波数据以后,可以对超声回波数据进行处理,例如滤波、放大、波束合成等处理。之后,可以基于处理后的超声回波数据,采用相关算法得到所需要的弹性测量参数。After that, based on each group of ultrasonic echo data, an elasticity measurement result is obtained. Wherein, the elasticity measurement result includes an elasticity parameter used to evaluate the degree of elasticity of the tissue in the target area, which may be the propagation velocity of the shear wave or the elastic modulus. Specifically, after receiving the ultrasonic echo data, the ultrasonic echo data can be processed, such as filtering, amplifying, and beam synthesis. After that, based on the processed ultrasonic echo data, relevant algorithms can be used to obtain the required elastic measurement parameters.
获得至少两个弹性测量结果以后,对所获得的弹性测量结果进行统计运算,以得到综合弹性测量结果,从而更准确完整地反映组织的弹性信息。其中,所述统计运算包括以下中的一项或多项:至少两个弹性测量结果的平均值、中值、方差、标准差、四分位值等等。After obtaining at least two elasticity measurement results, statistical operations are performed on the obtained elasticity measurement results to obtain a comprehensive elasticity measurement result, thereby more accurately and completely reflecting the organization's elasticity information. Wherein, the statistical operation includes one or more of the following: average value, median value, variance, standard deviation, quartile value, etc. of at least two elasticity measurement results.
在一些实施例中,在计算出综合弹性测量结果后,可以直接将计算出的综合弹性测量结果通过输出设备进行输出。其中,所述输出设备可以是显示装置,例如显示屏或显示器等等,综合弹性测量结果可以在显示装置的显示界面上进行显示。In some embodiments, after the comprehensive elasticity measurement result is calculated, the calculated comprehensive elasticity measurement result can be directly output through the output device. Wherein, the output device may be a display device, such as a display screen or a display, etc., and the comprehensive elasticity measurement result may be displayed on the display interface of the display device.
重新参照图6,本申请实施例还提供了一种超声成像系统600,超声成像系统600可以用于实现上述方法700。超声成像系统600可以包括超声探头610、发射/接收电路612、处理器614和输出设备618等部件。其中,超声探头610、发射/接收电路612、处理器614和输出设备618的具体细节可以参照图1所示的超声成像系统100中的超声探头110、发射/接收电路114、处理器116和输出设备118,以下仅对超声成像系统600的主要部件和各部件的主要功能进行了描述,而省略了以上已经描述过的细节内容。各个部件的其他相关描述可以参照上文对超声成像系统100和声衰减参数测量方法600的具体描述。Referring again to FIG. 6, an embodiment of the present application also provides an ultrasound imaging system 600, and the ultrasound imaging system 600 may be used to implement the above method 700. The ultrasound imaging system 600 may include components such as an ultrasound probe 610, a transmitting/receiving circuit 612, a processor 614, and an output device 618. Among them, the specific details of the ultrasonic probe 610, the transmitting/receiving circuit 612, the processor 614, and the output device 618 can refer to the ultrasonic probe 110, the transmitting/receiving circuit 114, the processor 116, and the output device in the ultrasonic imaging system 100 shown in FIG. For the device 118, only the main components of the ultrasound imaging system 600 and the main functions of each component are described below, and the details that have been described above are omitted. For other related descriptions of the various components, reference may be made to the detailed description of the ultrasound imaging system 100 and the sound attenuation parameter measurement method 600 above.
在本实施例中,超声成像系统600可以实现为瞬时弹性超声成像系统,则该超声成像系统600可以包括振动器,用于对被测对象的目标区域施加机械振动以产生剪切波,从而启动瞬时弹性测量,具体参见超声成像系统100中的振动器112。或者,超声成像系统600也可以实现为声辐射力弹性成像 系统,则超声成像系统600可以不包括振动器,由超声探头610对被测对象的目标区域施加声辐射力脉冲以产生剪切波,从而启动声辐射力弹性测量。In this embodiment, the ultrasound imaging system 600 may be implemented as a transient elastic ultrasound imaging system, and the ultrasound imaging system 600 may include a vibrator for applying mechanical vibration to the target area of the measured object to generate shear waves, thereby starting For the instantaneous elasticity measurement, refer to the vibrator 112 in the ultrasound imaging system 100 for details. Alternatively, the ultrasound imaging system 600 can also be implemented as an acoustic radiation force elastic imaging system. The ultrasound imaging system 600 may not include a vibrator. The ultrasound probe 610 applies acoustic radiation force pulses to the target area of the object to be measured to generate shear waves. This starts the elastic measurement of acoustic radiation force.
在超声成像系统600中,超声探头110包括多个阵元(即换能器阵元),因而能够在较宽频带下发射和接收超声波;发射/接收电路612用于激励所述超声探头610依次采用至少两个弹性测量超声频率向被测对象的目标区域发射跟踪剪切波的超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;处理器614用于根据所述超声回波数据获得每个所述超声频率下的所述目标区域的弹性测量结果,以及综合至少两个所述弹性测量结果,以确定综合弹性测量结果;输出设备618用于输出所述综合弹性测量结果。In the ultrasound imaging system 600, the ultrasound probe 110 includes multiple array elements (ie, transducer array elements), so that it can transmit and receive ultrasound in a wider frequency band; the transmitting/receiving circuit 612 is used to excite the ultrasound probe 610 in turn At least two elastic measurement ultrasonic frequencies are used to transmit ultrasonic waves tracking shear waves to the target area of the measured object, and receive ultrasonic echoes of the target area to obtain at least two sets of ultrasonic echo data; the processor 614 is configured to The ultrasonic echo data obtains the elasticity measurement result of the target area at each of the ultrasonic frequencies, and synthesizes at least two of the elasticity measurement results to determine the comprehensive elasticity measurement result; the output device 618 is used to output the elasticity measurement result. Comprehensive resilience measurement results.
基于以上描述,根据本申请实施例的弹性测量方法和超声成像系统,通过使用包括多个阵元的超声探头,可以在不切换探头的情况下,采用多个弹性测量超声频率进行弹性测量,并综合多次测量的结果以得到更为准确的综合弹性测量结果。Based on the above description, according to the elasticity measurement method and ultrasonic imaging system of the embodiments of the present application, by using an ultrasonic probe including multiple array elements, multiple elasticity measurement ultrasonic frequencies can be used for elasticity measurement without switching the probe, and Integrate the results of multiple measurements to obtain a more accurate comprehensive elasticity measurement result.
本申请另一实施例还提供一种声衰减参数测量方法,其基于包括多个阵元的超声探头,采用多个声衰减参数测量频率进行声衰减参数测量,并综合多次测量的结果以得到更为准确的综合测量结果。下面,将参考图8描述根据本申请一个实施例的声衰减参数测量方法。图8是本申请实施例的声衰减参数测量方法800的一个示意性流程图。Another embodiment of the present application also provides a sound attenuation parameter measurement method, which is based on an ultrasonic probe including multiple array elements, uses multiple sound attenuation parameter measurement frequencies to perform sound attenuation parameter measurement, and integrates the results of multiple measurements to obtain More accurate comprehensive measurement results. Hereinafter, a method for measuring sound attenuation parameters according to an embodiment of the present application will be described with reference to FIG. 8. FIG. 8 is a schematic flowchart of a method 800 for measuring sound attenuation parameters according to an embodiment of the present application.
如图8所示,所述声衰减参数测量方法800包括如下步骤:As shown in FIG. 8, the sound attenuation parameter measurement method 800 includes the following steps:
在步骤S810,基于包括多个阵元的超声探头,依次采用至少两个声衰减参数测量频率向被测对象的目标区域发射超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;In step S810, based on the ultrasonic probe including a plurality of array elements, at least two acoustic attenuation parameter measurement frequencies are used in sequence to transmit ultrasonic waves to the target area of the object to be measured, and receive ultrasonic echoes of the target area to obtain at least two sets Ultrasonic echo data;
在步骤S820,根据所述超声回波数据获得每个所述超声频率下的所述目标区域的声衰减参数测量结果;In step S820, obtain a sound attenuation parameter measurement result of the target area at each ultrasonic frequency according to the ultrasonic echo data;
在步骤S830,综合至少两个所述声衰减参数测量结果,以确定综合声衰减参数测量结果。In step S830, at least two of the sound attenuation parameter measurement results are integrated to determine a comprehensive sound attenuation parameter measurement result.
在本实施例中,由超声探头以至少两个声衰减参数测量频率依次向被测对象的目标区域发射超声波,并接收从目标区域返回的所述超声波的超声回波以获得超声回波数据。由于本申请实施例采用多阵元的超声探头,在较宽的频带下都具有较佳的灵敏度,因而可以基于同一把探头根据需要切换多个声衰减参数测量频率,在提高测量准确性的同时,无需切换探头,避免了繁琐的操作。In this embodiment, the ultrasonic probe sequentially transmits ultrasonic waves to the target area of the measured object at at least two sound attenuation parameter measurement frequencies, and receives ultrasonic echoes of the ultrasonic waves returned from the target area to obtain ultrasonic echo data. Since the embodiment of this application uses a multi-element ultrasonic probe, it has better sensitivity in a wider frequency band, so it is possible to switch multiple sound attenuation parameter measurement frequencies based on the same probe as needed, which improves measurement accuracy while improving measurement accuracy. , No need to switch probes, avoiding tedious operations.
之后,基于每组超声回波数据,获得一个声衰减参数测量结果。其中,所述声衰减参数测量结果衰减参数用于反映超声波在一定深度范围内传播时的声强度(或幅度、能量)的衰减程度,在临床中可用于脂肪肝程度的预测。After that, based on each group of ultrasonic echo data, a measurement result of acoustic attenuation parameters is obtained. Wherein, the measurement result of the sound attenuation parameter attenuation parameter is used to reflect the attenuation degree of the sound intensity (or amplitude, energy) when the ultrasonic wave propagates in a certain depth range, and can be used to predict the degree of fatty liver in clinical practice.
获得至少两个声衰减参数测量结果以后,对所获得的声衰减参数测量结果进行统计运算,以得到综合声衰减参数测量结果,从而更准确完整地反映组织的弹性信息。其中,所述统计运算包括以下中的一项或多项:至少两个声衰减参数测量结果的平均值、中值、方差、标准差、四分位值等等。After obtaining at least two sound attenuation parameter measurement results, statistical calculations are performed on the acquired sound attenuation parameter measurement results to obtain a comprehensive sound attenuation parameter measurement result, so as to more accurately and completely reflect the elasticity information of the tissue. Wherein, the statistical operation includes one or more of the following: average value, median value, variance, standard deviation, quartile value, etc. of at least two sound attenuation parameter measurement results.
在一些实施例中,在计算出综合声衰减参数测量结果后,可以直接将计算出的综合声衰减参数测量结果通过输出设备进行输出。其中,所述输出设备可以是显示装置,例如显示屏或显示器等等,综合声衰减参数测量结果可以在显示装置的显示界面上进行显示。In some embodiments, after the comprehensive sound attenuation parameter measurement result is calculated, the calculated comprehensive sound attenuation parameter measurement result can be directly output through the output device. Wherein, the output device may be a display device, such as a display screen or a display, etc., and the measurement result of the comprehensive sound attenuation parameter may be displayed on the display interface of the display device.
重新参照图6,本申请实施例还提供了一种超声成像系统600,超声成像系统600可以用于实现上述方法800。超声成像系统600可以包括超声探头610、发射/接收电路612、处理器614和输出设备618等部件。其中,超声探头610、发射/接收电路612、处理器614和输出设备618的具体细节可以参照图1所示的超声成像系统100中的超声探头110、发射/接收电路114、处理器116和输出设备118,以下仅对超声成像系统600的主要部件和各部件的主要功能进行了描述,而省略了以上已经描述过的细节内容。各个部件的其他相关描述可以参照上文对超声成像系统100和声衰减参数测量方法600的具体描述。6 again, an embodiment of the present application also provides an ultrasound imaging system 600, which can be used to implement the above method 800. The ultrasound imaging system 600 may include components such as an ultrasound probe 610, a transmitting/receiving circuit 612, a processor 614, and an output device 618. Among them, the specific details of the ultrasonic probe 610, the transmitting/receiving circuit 612, the processor 614, and the output device 618 can refer to the ultrasonic probe 110, the transmitting/receiving circuit 114, the processor 116, and the output device in the ultrasonic imaging system 100 shown in FIG. For the device 118, only the main components of the ultrasound imaging system 600 and the main functions of each component are described below, and the details that have been described above are omitted. For other related descriptions of the various components, reference may be made to the detailed description of the ultrasound imaging system 100 and the sound attenuation parameter measurement method 600 above.
在超声成像系统600中,超声探头110包括多个阵元(即换能器阵元),因而能够在较宽频带下发射和接收超声波;发射/接收电路612用于激励所述超声探头610依次采用至少两个声衰减参数测量频率向被测对象的目标区域发射超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;处理器614用于根据所述超声回波数据获得每个所述超声频率下的所述目标区域的声衰减参数测量结果,以及综合至少两个所述声衰减参数测量结果,以确定综合声衰减参数测量结果;输出设备618用于输出所述综合声衰减参数测量结果。In the ultrasound imaging system 600, the ultrasound probe 110 includes multiple array elements (ie, transducer array elements), so that it can transmit and receive ultrasound in a wider frequency band; the transmitting/receiving circuit 612 is used to excite the ultrasound probe 610 in turn At least two sound attenuation parameter measurement frequencies are used to transmit ultrasonic waves to the target area of the object to be measured, and receive ultrasonic echoes of the target area to obtain at least two sets of ultrasonic echo data; the processor 614 is configured to according to the ultrasonic echo The wave data obtains the sound attenuation parameter measurement result of the target area at each of the ultrasonic frequencies, and integrates at least two of the sound attenuation parameter measurement results to determine the comprehensive sound attenuation parameter measurement result; the output device 618 is used to output The comprehensive sound attenuation parameter measurement result.
基于以上描述,根据本申请实施例的声衰减参数测量方法和超声成像系统,通过使用包括多个阵元的超声探头,可以在不切换探头的情况下,采用多个声衰减参数测量频率进行声衰减参数测量,并综合多次测量的结果以得到更为准确的综合弹性测量结果。Based on the above description, according to the sound attenuation parameter measurement method and ultrasonic imaging system of the embodiments of the present application, by using an ultrasonic probe including multiple array elements, multiple sound attenuation parameter measurement frequencies can be used to perform sound without switching the probe. The attenuation parameter is measured, and the results of multiple measurements are integrated to obtain a more accurate comprehensive elasticity measurement result.
本申请实施例还提供了一种瞬时弹性测量方法,参照图9。图9是本申请实施例的瞬时弹性测量方法900的一个示意性流程图。The embodiment of the present application also provides a method for measuring instantaneous elasticity, refer to FIG. 9. FIG. 9 is a schematic flowchart of an instantaneous elasticity measurement method 900 according to an embodiment of the present application.
如图9所示,所述瞬时弹性测量方法900包括如下步骤:As shown in FIG. 9, the instantaneous elasticity measurement method 900 includes the following steps:
步骤S910,确定适用于被测对象的机械振动振幅,并根据所述机械振动振幅确定机械振动的驱动强度;Step S910, determining the mechanical vibration amplitude applicable to the measured object, and determining the driving intensity of the mechanical vibration according to the mechanical vibration amplitude;
步骤S920,采用所述驱动强度对所述被测对象施加所述机械振动振幅的机械振动,以在所述被测对象的目标区域内产生剪切波;Step S920, applying the driving intensity to the measured object with the mechanical vibration of the mechanical vibration amplitude, so as to generate a shear wave in the target area of the measured object;
步骤S930,向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超声回波,以获得超声回波数据;Step S930, transmitting ultrasonic waves tracking the shear wave to the target area, and receiving ultrasonic echoes of the target area to obtain ultrasonic echo data;
步骤S940,根据所述超声回波数据获得所述目标区域的瞬时弹性测量结果。Step S940: Obtain an instantaneous elasticity measurement result of the target area according to the ultrasonic echo data.
在本实施例中,以振动器设置在超声探头内部为例来进行描述,但应理解,振动器还可以与超声探头相互独立。当超声探头本身包括振动器时,可以向超声探头的振动器输出用于驱动振动器振动的驱动信号以实施瞬时弹性测量,振动器接收到驱动信号以后产生机械振动,从而使与被测对象体表接触的超声探头振动,并通过超声探头将振动产生的剪切波传送至被测对象目标区域的组织中,以在目标区域的组织内部生成剪切波,该剪切波行经选定的感兴趣区域。In this embodiment, the vibrator is provided inside the ultrasonic probe as an example for description, but it should be understood that the vibrator can also be independent of the ultrasonic probe. When the ultrasonic probe itself includes a vibrator, a driving signal for driving the vibrator to vibrate can be output to the vibrator of the ultrasonic probe to implement instantaneous elasticity measurement. The ultrasonic probe in contact with the surface vibrates, and the shear wave generated by the vibration is transmitted to the tissue in the target area of the measured object through the ultrasonic probe to generate a shear wave inside the tissue in the target area. The shear wave travels through the selected sensory area. Area of interest.
在本实施例中,由于不同的被测对象适用于不同的机械振动振幅,因此,在步骤S910中,确定适用于所述被测对象的机械振动振幅,并根据所述机械振动振幅确定所述机械振动的驱动强度,以所确定的驱动强度驱动振动器以产生满足要求的机械振动振幅。In this embodiment, because different measured objects are suitable for different mechanical vibration amplitudes, in step S910, determine the mechanical vibration amplitude suitable for the measured object, and determine the mechanical vibration amplitude according to the mechanical vibration amplitude. The driving intensity of the mechanical vibration is to drive the vibrator with the determined driving intensity to generate the mechanical vibration amplitude that meets the requirements.
其中,机械振动振幅的确定需要考虑到剪切波的穿透力和被测对象的承受力。因此,可以基于所述被测对象的体型、年龄、肋间距和/或健康状况等确定机械振动振幅。例如,大体型的被测对象或肋间距窄的被测对象需要较强的穿透力,因而适用于较大的机械振动振幅;幼年或健康状况较差的被测对象承受能力较差,因而适用于较小的机械振动振幅。Among them, the determination of the mechanical vibration amplitude needs to consider the penetration force of the shear wave and the endurance of the measured object. Therefore, the mechanical vibration amplitude can be determined based on the body shape, age, rib spacing, and/or health status of the measured object. For example, a large-sized test object or a test object with a narrow rib spacing requires stronger penetrating power, so it is suitable for larger mechanical vibration amplitudes; young or poorly-healthy test objects have poor bearing capacity, so Suitable for small mechanical vibration amplitude.
在一个实施例中,机械振动振幅的确定还可以与弹性测量超声频率的确定相关联。例如,选定弹性测量超声频率以后,自动确定预先设定的与之关联的机械振动振幅。In one embodiment, the determination of the mechanical vibration amplitude may also be associated with the determination of the elastic measurement ultrasonic frequency. For example, after selecting the elastic measurement ultrasonic frequency, the preset mechanical vibration amplitude associated with it is automatically determined.
在确定适用被测对象的机械振动振幅后,可以自动关联至预先设定的用于产生该机械振动振幅的振动器的驱动强度,并以该驱动强度驱动振动器, 以产生所述机械振动振幅的机械振动,进而在被测对象的目标区域产生剪切波。之后,执行上述步骤S930和步骤S940,向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超声回波,以获得超声回波数据,以及根据所述超声回波数据获得所述目标区域的瞬时弹性测量结果。步骤S920至步骤S940的其他具体细节参照瞬时弹性测量方法300中的相关描述,在此不再赘述。After determining the mechanical vibration amplitude applicable to the measured object, it can be automatically correlated to the preset driving intensity of the vibrator used to generate the mechanical vibration amplitude, and the vibrator is driven with the driving intensity to generate the mechanical vibration amplitude The mechanical vibration of the measured object generates a shear wave in the target area of the measured object. After that, the above steps S930 and S940 are executed, the ultrasonic wave tracking the shear wave is transmitted to the target area, and the ultrasonic echo of the target area is received to obtain ultrasonic echo data, and according to the ultrasonic echo The data obtains the instantaneous elasticity measurement result of the target area. For other specific details of step S920 to step S940, refer to the relevant description in the instantaneous elasticity measurement method 300, which will not be repeated here.
基于以上描述,根据本实施例的瞬时弹性测量方法根据被测对象的实际需要选择不同机械振动振幅的机械振动,从而满足临床中对不同强度机械振动的需求,有利于提高瞬时弹性测量的准确性和有效性,并且提升了用户体验。Based on the above description, according to the instantaneous elasticity measurement method of this embodiment, mechanical vibrations with different mechanical vibration amplitudes are selected according to the actual needs of the measured object, so as to meet the clinical needs for different intensities of mechanical vibration, which is beneficial to improve the accuracy of instantaneous elasticity measurement. And effectiveness, and enhance the user experience.
尽管这里已经参考附图描述了示例实施例,应理解上述示例实施例仅仅是示例性的,并且不意图将本申请的范围限制于此。本领域普通技术人员可以在其中进行各种改变和修改,而不偏离本申请的范围和精神。所有这些改变和修改意在被包括在所附权利要求所要求的本申请的范围之内。Although the exemplary embodiments have been described herein with reference to the accompanying drawings, it should be understood that the above-described exemplary embodiments are merely exemplary, and are not intended to limit the scope of the present application thereto. Those of ordinary skill in the art can make various changes and modifications therein without departing from the scope and spirit of the present application. All these changes and modifications are intended to be included within the scope of the present application as required by the appended claims.
本领域普通技术人员可以意识到,结合本文中所公开的实施例描述的各示例的单元及算法步骤,能够以电子硬件、或者计算机软件和电子硬件的结合来实现。这些功能究竟以硬件还是软件方式来执行,取决于技术方案的特定应用和设计约束条件。专业技术人员可以对每个特定的应用来使用不同方法来实现所描述的功能,但是这种实现不应认为超出本申请的范围。A person of ordinary skill in the art may realize that the units and algorithm steps of the examples described in combination with the embodiments disclosed herein can be implemented by electronic hardware or a combination of computer software and electronic hardware. Whether these functions are executed by hardware or software depends on the specific application and design constraint conditions of the technical solution. Professionals and technicians can use different methods for each specific application to implement the described functions, but such implementation should not be considered beyond the scope of this application.
在本申请所提供的几个实施例中,应该理解到,所揭露的设备和方法,可以通过其它的方式实现。例如,以上所描述的设备实施例仅仅是示意性的,例如,所述单元的划分,仅仅为一种逻辑功能划分,实际实现时可以有另外的划分方式,例如多个单元或组件可以结合或者可以集成到另一个设备,或一些特征可以忽略,或不执行。In the several embodiments provided in this application, it should be understood that the disclosed device and method may be implemented in other ways. For example, the device embodiments described above are only illustrative. For example, the division of the units is only a logical function division, and there may be other divisions in actual implementation, for example, multiple units or components may be combined or It can be integrated into another device, or some features can be ignored or not implemented.
在此处所提供的说明书中,说明了大量具体细节。然而,能够理解,本申请的实施例可以在没有这些具体细节的情况下实践。在一些实例中,并未详细示出公知的方法、结构和技术,以便不模糊对本说明书的理解。In the instructions provided here, a lot of specific details are explained. However, it can be understood that the embodiments of the present application can be practiced without these specific details. In some instances, well-known methods, structures, and technologies are not shown in detail, so as not to obscure the understanding of this specification.
类似地,应当理解,为了精简本申请并帮助理解各个发明方面中的一个或多个,在对本申请的示例性实施例的描述中,本申请的各个特征有时被一起分组到单个实施例、图、或者对其的描述中。然而,并不应将该本申请的方法解释成反映如下意图:即所要求保护的本申请要求比在每个权利要求中 所明确记载的特征更多的特征。更确切地说,如相应的权利要求书所反映的那样,其发明点在于可以用少于某个公开的单个实施例的所有特征的特征来解决相应的技术问题。因此,遵循具体实施方式的权利要求书由此明确地并入该具体实施方式,其中每个权利要求本身都作为本申请的单独实施例。Similarly, it should be understood that, in order to simplify this application and help understand one or more of the various aspects of the invention, in the description of the exemplary embodiments of this application, the various features of this application are sometimes grouped together into a single embodiment or figure. , Or in its description. However, the method of this application should not be interpreted as reflecting the intention that the claimed application requires more features than the features explicitly recorded in each claim. More precisely, as reflected in the corresponding claims, the point of the invention is that the corresponding technical problems can be solved with features that are less than all the features of a single disclosed embodiment. Therefore, the claims following the specific embodiment are thus explicitly incorporated into the specific embodiment, wherein each claim itself serves as a separate embodiment of the application.
本领域的技术人员可以理解,除了特征之间相互排斥之外,可以采用任何组合对本说明书(包括伴随的权利要求、摘要和附图)中公开的所有特征以及如此公开的任何方法或者设备的所有过程或单元进行组合。除非另外明确陈述,本说明书(包括伴随的权利要求、摘要和附图)中公开的每个特征可以由提供相同、等同或相似目的的替代特征来代替。Those skilled in the art can understand that in addition to mutual exclusion between the features, any combination of all features disclosed in this specification (including the accompanying claims, abstract, and drawings) and any method or device disclosed in this manner can be used. Processes or units are combined. Unless expressly stated otherwise, each feature disclosed in this specification (including the accompanying claims, abstract and drawings) may be replaced by an alternative feature providing the same, equivalent or similar purpose.
此外,本领域的技术人员能够理解,尽管在此所述的一些实施例包括其它实施例中所包括的某些特征而不是其它特征,但是不同实施例的特征的组合意味着处于本申请的范围之内并且形成不同的实施例。例如,在权利要求书中,所要求保护的实施例的任意之一都可以以任意的组合方式来使用。In addition, those skilled in the art can understand that although some embodiments described herein include certain features included in other embodiments but not other features, the combination of features of different embodiments means that they are within the scope of the present application. Within and form different embodiments. For example, in the claims, any one of the claimed embodiments can be used in any combination.
本申请的各个部件实施例可以以硬件实现,或者以在一个或者多个处理器上运行的软件模块实现,或者以它们的组合实现。本领域的技术人员应当理解,可以在实践中使用微处理器或者数字信号处理器(DSP)来实现根据本申请实施例的一些模块的一些或者全部功能。本申请还可以实现为用于执行这里所描述的方法的一部分或者全部的装置程序(例如,计算机程序和计算机程序产品)。这样的实现本申请的程序可以存储在计算机可读介质上,或者可以具有一个或者多个信号的形式。这样的信号可以从因特网网站上下载得到,或者在载体信号上提供,或者以任何其他形式提供。The various component embodiments of the present application may be implemented by hardware, or by software modules running on one or more processors, or by a combination of them. Those skilled in the art should understand that a microprocessor or a digital signal processor (DSP) may be used in practice to implement some or all of the functions of some modules according to the embodiments of the present application. This application can also be implemented as a device program (for example, a computer program and a computer program product) for executing part or all of the methods described herein. Such a program for implementing the present application may be stored on a computer-readable medium, or may have the form of one or more signals. Such a signal can be downloaded from an Internet website, or provided on a carrier signal, or provided in any other form.
应该注意的是上述实施例对本申请进行说明而不是对本申请进行限制,并且本领域技术人员在不脱离所附权利要求的范围的情况下可设计出替换实施例。在权利要求中,不应将位于括号之间的任何参考符号构造成对权利要求的限制。本申请可以借助于包括有若干不同元件的硬件以及借助于适当编程的计算机来实现。在列举了若干装置的单元权利要求中,这些装置中的若干个可以是通过同一个硬件项来具体体现。单词第一、第二、以及第三等的使用不表示任何顺序。可将这些单词解释为名称。It should be noted that the above-mentioned embodiments illustrate rather than limit the application, and those skilled in the art can design alternative embodiments without departing from the scope of the appended claims. In the claims, any reference signs placed between parentheses should not be constructed as a limitation to the claims. The application can be realized by means of hardware including several different elements and by means of a suitably programmed computer. In the unit claims listing several devices, several of these devices may be embodied in the same hardware item. The use of the words first, second, and third, etc. do not indicate any order. These words can be interpreted as names.
以上所述,仅为本申请的具体实施方式或对具体实施方式的说明,本申请的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本申请揭露的技术范围内,可轻易想到变化或替换,都应涵盖在本申请的保护范围之内。 本申请的保护范围应以权利要求的保护范围为准。The above are only specific implementations of this application or descriptions of specific implementations. The scope of protection of this application is not limited to this. Anyone familiar with the technical field within the technical scope disclosed in this application can easily Any change or replacement should be covered within the scope of protection of this application. The protection scope of this application shall be subject to the protection scope of the claims.

Claims (40)

  1. 一种瞬时弹性测量方法,其特征在于,所述方法包括:A method for measuring instantaneous elasticity, characterized in that the method comprises:
    确定适用于被测对象的弹性测量超声频率;Determine the elastic measurement ultrasonic frequency suitable for the measured object;
    对所述被测对象施加机械振动,以在所述被测对象的目标区域内产生剪切波;Applying mechanical vibration to the measured object to generate a shear wave in the target area of the measured object;
    通过包括多个阵元的超声探头,采用所述弹性测量超声频率向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超声回波,以获得超声回波数据;Using the elastic measuring ultrasonic frequency to transmit ultrasonic waves that track the shear wave to the target area by using an ultrasonic probe including a plurality of array elements, and receive ultrasonic echoes of the target area to obtain ultrasonic echo data;
    根据所述超声回波数据获得所述目标区域的瞬时弹性测量结果。Obtain the instantaneous elasticity measurement result of the target area according to the ultrasonic echo data.
  2. 根据权利要求1所述的方法,其特征在于,所述确定适用于被测对象的弹性测量超声频率包括:The method according to claim 1, wherein the determining the elasticity measurement ultrasonic frequency suitable for the measured object comprises:
    获取表征所述被测对象的个体特征的数据;Acquiring data characterizing the individual characteristics of the measured object;
    根据所述表征所述被测对象的个体特征的数据确定所述弹性测量超声频率。The elasticity measurement ultrasonic frequency is determined according to the data characterizing the individual characteristics of the measured object.
  3. 根据权利要求2所述的方法,其特征在于,所述根据所述表征所述被测对象的个体特征的数据确定所述弹性测量超声频率,包括:The method according to claim 2, wherein the determining the elasticity measurement ultrasonic frequency according to the data characterizing the individual characteristics of the measured object comprises:
    将预先设定的与所述表征所述被测对象的个体特征的数据相关联的频率确定为所述弹性测量超声频率。The pre-set frequency associated with the data characterizing the individual characteristics of the measured object is determined as the elasticity measurement ultrasonic frequency.
  4. 根据权利要求2或3所述的方法,其特征在于,所述表征所述被测对象的个体特征的数据包括表征所述被测对象的体型、年龄、肋间距和/或健康状况的数据。The method according to claim 2 or 3, wherein the data characterizing the individual characteristics of the measured object includes data characterizing the body shape, age, rib spacing, and/or health status of the measured object.
  5. 根据权利要求2所述的方法,其特征在于,所述表征所述被测对象的个体特征的数据包括所述被测对象的所述目标区域的超声图像数据。The method according to claim 2, wherein the data characterizing the individual characteristics of the measured object comprises ultrasound image data of the target area of the measured object.
  6. 根据权利要求5所述的方法,其特征在于,所述获取表征所述被测对象的个体特征的数据包括:采用多个超声频率分别采集所述被测对象的所述目标区域的超声图像数据,The method according to claim 5, wherein the acquiring data characterizing the individual characteristics of the measured object comprises: separately acquiring ultrasound image data of the target area of the measured object using a plurality of ultrasound frequencies ,
    所述根据所述表征所述被测对象的个体特征的数据确定所述弹性测量超声频率,包括:The determining the elasticity measurement ultrasonic frequency according to the data characterizing the individual characteristics of the measured object includes:
    分析所述多个超声频率下的所述超声图像数据,并将满足预定标准的超声图像数据所对应的超声频率作为所述弹性测量超声频率。The ultrasound image data at the multiple ultrasound frequencies is analyzed, and the ultrasound frequency corresponding to the ultrasound image data meeting a predetermined standard is used as the elasticity measurement ultrasound frequency.
  7. 根据权利要求6所述的方法,其特征在于,所述满足预定标准的超声图像数据包括多个所述超声图像数据中分辨率和/或信噪比最佳的超声图像数据。The method according to claim 6, wherein the ultrasound image data that meets a predetermined standard comprises a plurality of ultrasound image data with the best resolution and/or signal-to-noise ratio among the ultrasound image data.
  8. 根据权利要求5所述的方法,其特征在于,所述根据所述表征所述被测对象的个体特征的数据确定所述弹性测量超声频率,包括:The method according to claim 5, wherein the determining the elasticity measurement ultrasonic frequency according to the data characterizing the individual characteristics of the measured object comprises:
    基于所述超声图像数据测量所述被测对象的个体特征参数;Measuring the individual characteristic parameters of the measured object based on the ultrasound image data;
    根据所述个体特征参数确定适用于所述被测对象的所述弹性测量超声频率。The elasticity measurement ultrasonic frequency suitable for the measured object is determined according to the individual characteristic parameter.
  9. 根据权利要求8所述的方法,其特征在于,所述个体特征参数包括体表-肝包膜距离。The method according to claim 8, wherein the individual characteristic parameter includes a body surface-liver envelope distance.
  10. 根据权利要求9所述的方法,其特征在于,所述体表-肝包膜距离越大,所述弹性测量超声频率越低。The method according to claim 9, wherein the greater the distance between the body surface and the liver capsule, the lower the elasticity measurement ultrasound frequency.
  11. 根据权利要求8所述的方法,其特征在于,所述基于所述超声图像数据测量所述被测对象的个体特征参数包括自动测量或用户手动测量。The method according to claim 8, wherein the measuring the individual characteristic parameters of the measured object based on the ultrasound image data comprises automatic measurement or manual measurement by a user.
  12. 根据权利要求1-11之一所述的方法,其特征在于,所述方法还包括:The method according to any one of claims 1-11, wherein the method further comprises:
    输出建议采用所述弹性测量超声频率以进行瞬时弹性测量的提示信息;Outputting a prompt message suggesting that the elasticity measurement ultrasonic frequency is used for instantaneous elasticity measurement;
    根据接收到的用户指令确定是否将所述超声探头的发射和接收频率切换为所述弹性测量超声频率。It is determined whether to switch the transmitting and receiving frequencies of the ultrasonic probe to the elasticity measurement ultrasonic frequency according to the received user instruction.
  13. 根据权利要求1所述的方法,其特征在于,还包括:The method according to claim 1, further comprising:
    根据所述弹性测量超声频率确定用于获得所述瞬时弹性测量结果的感兴趣区域的深度范围。The depth range of the region of interest for obtaining the instantaneous elasticity measurement result is determined according to the elasticity measurement ultrasonic frequency.
  14. 根据权利要求13所述的方法,其特征在于,所述根据所述弹性测量超声频率确定用于获得所述瞬时弹性测量结果的感兴趣区域的深度范围,包括:The method according to claim 13, wherein the determining the depth range of the region of interest for obtaining the instantaneous elasticity measurement result according to the elasticity measurement ultrasonic frequency comprises:
    当确定所述弹性测量超声频率时,自动在预先设定的与所述弹性测量超声频率相关联的深度范围内确定所述感兴趣区域的深度范围。When the elasticity measurement ultrasonic frequency is determined, the depth range of the region of interest is automatically determined within the preset depth range associated with the elasticity measurement ultrasonic frequency.
  15. 根据权利要求13或14所述的方法,其特征在于,所述弹性测量超声频率越低,所述感兴趣区域的深度越深。The method according to claim 13 or 14, wherein the lower the elasticity measurement ultrasonic frequency, the deeper the depth of the region of interest.
  16. 根据权利要求9所述的方法,其特征在于,还包括:The method according to claim 9, further comprising:
    根据所述被测对象的所述体表-肝包膜距离确定用于获得所述瞬时弹性测量结果的感兴趣区域的深度范围。The depth range of the region of interest for obtaining the instantaneous elasticity measurement result is determined according to the body surface-liver envelope distance of the measured object.
  17. 根据权利要求1所述的方法,其特征在于,还包括:The method according to claim 1, further comprising:
    根据用户输入确定用于获得所述瞬时弹性测量结果的感兴趣区域的深度范围。The depth range of the region of interest used to obtain the instantaneous elasticity measurement result is determined according to the user input.
  18. 根据权利要求1所述的方法,其特征在于,还包括:The method according to claim 1, further comprising:
    确定适用于所述被测对象的声衰减参数测量频率;Determine the sound attenuation parameter measurement frequency suitable for the measured object;
    通过所述超声探头,采用所述声衰减参数测量频率向被测对象的目标区域发射超声波,并接收所述目标区域的超声回波,以获得超声回波数据;Using the ultrasonic probe to use the sound attenuation parameter measurement frequency to transmit ultrasonic waves to a target area of the measured object, and receive ultrasonic echoes of the target area to obtain ultrasonic echo data;
    根据所述超声回波数据获得所述目标区域的声衰减参数测量结果。Obtain the sound attenuation parameter measurement result of the target area according to the ultrasonic echo data.
  19. 根据权利要求18所述的方法,其特征在于,所述确定适用于所述被测对象的声衰减参数测量频率包括:The method according to claim 18, wherein the determining the sound attenuation parameter measurement frequency applicable to the measured object comprises:
    根据所述被测对象的体型、肋间距和/或健康状况确定所述声衰减参数测量频率。The sound attenuation parameter measurement frequency is determined according to the body shape, rib spacing and/or health condition of the measured object.
  20. 根据权利要求1所述的方法,其特征在于,还包括:The method according to claim 1, further comprising:
    确定适用于所述被测对象的机械振动振幅;以及Determine the mechanical vibration amplitude applicable to the measured object; and
    根据所述机械振动振幅确定所述机械振动的驱动强度。The driving intensity of the mechanical vibration is determined according to the amplitude of the mechanical vibration.
  21. 根据权利要求20所述的方法,其特征在于,所述确定适用于所述被测对象的机械振动振幅包括:The method according to claim 20, wherein the determining the mechanical vibration amplitude applicable to the measured object comprises:
    基于所述被测对象的体型、年龄、肋间距和/或健康状况确定所述机械振动振幅。The mechanical vibration amplitude is determined based on the body shape, age, rib spacing, and/or health status of the measured object.
  22. 一种声衰减参数测量方法,其特征在于,所述方法包括:A method for measuring sound attenuation parameters, characterized in that the method includes:
    确定适用于被测对象的声衰减参数测量频率;Determine the sound attenuation parameter measurement frequency suitable for the measured object;
    通过包括多个阵元的超声探头,采用所述声衰减参数测量频率向所述被测对象的目标区域发射超声波,并接收所述目标区域的超声回波,以获得超声回波数据;Using the acoustic attenuation parameter measurement frequency to transmit ultrasonic waves to the target area of the measured object by using an ultrasonic probe including a plurality of array elements, and receive ultrasonic echoes of the target area to obtain ultrasonic echo data;
    根据所述超声回波数据获得所述目标区域的声衰减参数测量结果。Obtain the sound attenuation parameter measurement result of the target area according to the ultrasonic echo data.
  23. 根据权利要求22所述的方法,其特征在于,所述确定适用于被测对象的声衰减参数测量频率包括:The method according to claim 22, wherein the determining the sound attenuation parameter measurement frequency suitable for the measured object comprises:
    获取表征所述被测对象的个体特征的数据;Acquiring data characterizing the individual characteristics of the measured object;
    根据所述表征所述被测对象的个体特征的数据确定所述声衰减参数测量频率。The measurement frequency of the sound attenuation parameter is determined according to the data characterizing the individual characteristics of the measured object.
  24. 根据权利要求23所述的方法,其特征在于,所述根据所述表征所述被测对象的个体特征的数据确定所述声衰减参数测量频率,包括:The method according to claim 23, wherein the determining the sound attenuation parameter measurement frequency according to the data characterizing the individual characteristics of the measured object comprises:
    将预先设定的与所述表征所述被测对象的个体特征的数据相关联的频率确定为所述声衰减参数测量频率。The preset frequency associated with the data characterizing the individual characteristics of the measured object is determined as the sound attenuation parameter measurement frequency.
  25. 根据权利要求23或24所述的方法,其特征在于,所述表征所述被测对象的个体特征的数据包括表征所述被测对象的体型、年龄、肋间距和/或健康状况的数据。The method according to claim 23 or 24, wherein the data characterizing the individual characteristics of the measured object includes data characterizing the body shape, age, rib spacing, and/or health status of the measured object.
  26. 根据权利要求23所述的方法,其特征在于,所述表征所述被测对象 的个体特征的数据包括所述被测对象的所述目标区域的超声图像数据。The method according to claim 23, wherein the data characterizing the individual characteristics of the measured object comprises ultrasound image data of the target area of the measured object.
  27. 根据权利要求26所述的方法,其特征在于,所述获取表征所述被测对象的个体特征的数据包括:采用多个超声频率分别采集所述被测对象的所述目标区域的超声图像数据,The method according to claim 26, wherein said acquiring data characterizing the individual characteristics of the measured object comprises: separately acquiring ultrasound image data of the target area of the measured object using a plurality of ultrasound frequencies ,
    所述根据所述表征所述被测对象的个体特征的数据确定所述声衰减参数测量频率,包括:The determining the sound attenuation parameter measurement frequency according to the data characterizing the individual characteristics of the measured object includes:
    对比所述多个超声频率下的所述超声图像数据,并将满足预定标准的超声图像数据所对应的超声频率作为所述声衰减参数测量频率。The ultrasound image data at the multiple ultrasound frequencies are compared, and the ultrasound frequency corresponding to the ultrasound image data meeting a predetermined standard is used as the sound attenuation parameter measurement frequency.
  28. 根据权利要求26所述的方法,其特征在于,所述根据所述表征所述被测对象的个体特征的数据确定所述声衰减参数测量频率,包括:The method according to claim 26, wherein the determining the sound attenuation parameter measurement frequency according to the data characterizing the individual characteristics of the measured object comprises:
    基于所述超声图像数据测量所述被测对象的个体特征参数;Measuring the individual characteristic parameters of the measured object based on the ultrasound image data;
    根据所述个体特征参数确定适用于所述被测对象的所述声衰减参数测量频率。The measurement frequency of the sound attenuation parameter suitable for the measured object is determined according to the individual characteristic parameter.
  29. 根据权利要求28所述的方法,其特征在于,所述个体特征参数包括体表-肝包膜距离。The method according to claim 28, wherein the individual characteristic parameter comprises a body surface-liver envelope distance.
  30. 一种弹性测量方法,其特征在于,所述方法包括:An elasticity measurement method, characterized in that the method includes:
    基于包括多个阵元的超声探头,依次采用至少两个弹性测量超声频率向被测对象的目标区域发射跟踪剪切波的超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;Based on an ultrasound probe that includes a plurality of array elements, at least two elasticity measurement ultrasound frequencies are used in sequence to transmit shear wave-tracking ultrasound to the target area of the object to be measured, and receive the ultrasound echoes of the target area to obtain at least two sets Ultrasonic echo data;
    根据所述超声回波数据获得每个所述超声频率下的所述目标区域的弹性测量结果;Obtaining an elasticity measurement result of the target area at each ultrasonic frequency according to the ultrasonic echo data;
    综合至少两个所述弹性测量结果,以确定综合弹性测量结果。At least two of the elasticity measurement results are combined to determine a comprehensive elasticity measurement result.
  31. 根据权利要求30所述的方法,其特征在于,还包括:The method according to claim 30, further comprising:
    基于机械振动在所述被测对象的所述目标区域产生所述剪切波;或者Generating the shear wave in the target area of the measured object based on mechanical vibration; or
    基于声辐射力在所述被测对象的所述目标区域产生所述剪切波。The shear wave is generated in the target area of the measured object based on the acoustic radiation force.
  32. 一种声衰减参数测量方法,其特征在于,所述方法包括:A method for measuring sound attenuation parameters, characterized in that the method includes:
    基于包括多个阵元的超声探头,依次采用至少两个声衰减参数测量频率向被测对象的目标区域发射超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;Based on an ultrasonic probe including multiple array elements, at least two acoustic attenuation parameter measurement frequencies are used to transmit ultrasonic waves to the target area of the object to be measured, and receive ultrasonic echoes of the target area to obtain at least two sets of ultrasonic echo data ;
    根据所述超声回波数据获得每个所述超声频率下的所述目标区域的声衰减参数测量结果;Obtaining, according to the ultrasonic echo data, a measurement result of the sound attenuation parameter of the target area at each of the ultrasonic frequencies;
    综合至少两个所述声衰减参数测量结果,以确定综合声衰减参数测量结果。At least two of the sound attenuation parameter measurement results are combined to determine a comprehensive sound attenuation parameter measurement result.
  33. 一种瞬时弹性测量方法,其特征在于,所述方法包括:A method for measuring instantaneous elasticity, characterized in that the method comprises:
    确定适用于被测对象的机械振动振幅,并根据所述机械振动振幅确定机械振动的驱动强度;Determine the mechanical vibration amplitude suitable for the measured object, and determine the driving strength of the mechanical vibration according to the mechanical vibration amplitude;
    采用所述驱动强度对所述被测对象施加所述机械振动振幅的机械振动,以在所述被测对象的目标区域内产生剪切波;Applying the driving intensity to the measured object with the mechanical vibration of the mechanical vibration amplitude, so as to generate a shear wave in the target area of the measured object;
    向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超声回波,以获得超声回波数据;Transmitting ultrasonic waves that track the shear wave to the target area, and receiving ultrasonic echoes of the target area to obtain ultrasonic echo data;
    根据所述超声回波数据获得所述目标区域的瞬时弹性测量结果。Obtain the instantaneous elasticity measurement result of the target area according to the ultrasonic echo data.
  34. 一种超声成像系统,其特征在于,包括:An ultrasound imaging system, characterized in that it comprises:
    超声探头,所述超声探头包括多个阵元;An ultrasonic probe, the ultrasonic probe includes a plurality of array elements;
    振动器,用于对被测对象施加机械振动,以在所述被测对象的目标区域内产生剪切波;A vibrator for applying mechanical vibration to the measured object to generate a shear wave in the target area of the measured object;
    发射/接收电路,用于激励所述超声探头采用适用于所述被测对象的弹性测量超声频率向所述目标区域发射跟踪所述剪切波的超声波,并接收所述目标区域的超声回波,以获得超声回波数据;The transmitting/receiving circuit is used to excite the ultrasonic probe to use the elastic measurement ultrasonic frequency suitable for the measured object to transmit the ultrasonic wave tracking the shear wave to the target area, and to receive the ultrasonic echo of the target area To obtain ultrasonic echo data;
    处理器,用于:Processor for:
    确定所述弹性测量超声频率;以及Determining the elasticity measurement ultrasonic frequency; and
    对所述超声回波数据进行处理,以获得所述目标区域的瞬时弹性测量结果;Processing the ultrasonic echo data to obtain the instantaneous elasticity measurement result of the target area;
    输出设备,用于输出所述瞬时弹性测量结果。The output device is used to output the instantaneous elasticity measurement result.
  35. 根据权利要求34所述的超声成像系统,其特征在于,所述输出设备还用于输出建议采用所述弹性测量超声频率以进行瞬时弹性测量的提示信息;The ultrasonic imaging system according to claim 34, wherein the output device is further configured to output a prompt message suggesting that the elasticity measurement ultrasonic frequency is used for instantaneous elasticity measurement;
    所述处理器还用于根据接收到的用户指令确定是否将所述超声探头的发射和接收频率切换为所述弹性测量超声频率。The processor is further configured to determine whether to switch the transmitting and receiving frequencies of the ultrasonic probe to the elasticity measurement ultrasonic frequency according to the received user instruction.
  36. 一种超声成像系统,其特征在于,包括:An ultrasound imaging system, characterized in that it comprises:
    超声探头,所述超声探头包括多个阵元;An ultrasonic probe, the ultrasonic probe includes a plurality of array elements;
    发射/接收电路,用于激励所述超声探头依次采用至少两个弹性测量超声频率向所述目标区域发射跟踪剪切波的超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;The transmitting/receiving circuit is used to excite the ultrasonic probe to use at least two elasticity measuring ultrasonic frequencies to transmit ultrasonic waves tracking shear waves to the target area in turn, and receive ultrasonic echoes from the target area to obtain at least two sets Ultrasonic echo data;
    处理器,用于:Processor for:
    对所述至少两组超声回波数据进行处理,以获得所述目标区域的至少两组弹性测量结果;Processing the at least two sets of ultrasonic echo data to obtain at least two sets of elastic measurement results of the target area;
    综合所述至少两组弹性测量结果,以得到综合弹性测量结果。The at least two sets of elasticity measurement results are synthesized to obtain a comprehensive elasticity measurement result.
  37. 根据权利要求36所述的超声成像系统,其特征在于,还包括:The ultrasound imaging system of claim 36, further comprising:
    振动器,用于对被测对象施加机械振动,以在所述被测对象的目标区域内产生所述剪切波。The vibrator is used to apply mechanical vibration to the measured object to generate the shear wave in the target area of the measured object.
  38. 根据权利要求36所述的超声成像系统,其特征在于,所述超声探头还用于基于声辐射力在所述被测对象的目标区域内产生所述剪切波。The ultrasound imaging system according to claim 36, wherein the ultrasound probe is further configured to generate the shear wave in a target area of the measured object based on acoustic radiation force.
  39. 一种超声成像系统,其特征在于,包括:An ultrasound imaging system, characterized in that it comprises:
    超声探头,所述超声探头包括多个阵元;An ultrasonic probe, the ultrasonic probe includes a plurality of array elements;
    发射/接收电路,用于激励所述超声探头采用适用于所述被测对象的声衰减参数测量频率向所述目标区域发射超声波,并接收所述目标区域的超声回波,以获得超声回波数据;The transmitting/receiving circuit is used to excite the ultrasonic probe to use the sound attenuation parameter measurement frequency suitable for the measured object to transmit ultrasonic waves to the target area and receive the ultrasonic echo of the target area to obtain the ultrasonic echo data;
    处理器,用于:Processor for:
    确定所述声衰减参数测量频率;以及Determining the sound attenuation parameter measurement frequency; and
    对所述超声回波数据进行处理,以获得所述目标区域的声衰减参数测量结果;Processing the ultrasonic echo data to obtain a measurement result of the acoustic attenuation parameter of the target area;
    输出设备,用于输出所述声衰减参数测量结果。The output device is used to output the measurement result of the sound attenuation parameter.
  40. 一种超声成像系统,其特征在于,包括:An ultrasound imaging system, characterized in that it comprises:
    超声探头,所述超声探头包括多个阵元;An ultrasonic probe, the ultrasonic probe includes a plurality of array elements;
    发射/接收电路,用于激励所述超声探头依次采用至少两个声衰减参数频率向所述目标区域发射超声波,并接收所述目标区域的超声回波,以获得至少两组超声回波数据;A transmitting/receiving circuit for stimulating the ultrasonic probe to sequentially use at least two acoustic attenuation parameter frequencies to transmit ultrasonic waves to the target area and receive ultrasonic echoes of the target area to obtain at least two sets of ultrasonic echo data;
    处理器,用于:Processor for:
    对所述至少两组超声回波数据进行处理,以获得所述目标区域的至少两组声衰减参数测量结果;Processing the at least two sets of ultrasonic echo data to obtain at least two sets of sound attenuation parameter measurement results of the target area;
    综合所述至少两组声衰减参数测量结果,以得到综合声衰减参数测量结果;Synthesize the at least two sets of sound attenuation parameter measurement results to obtain a comprehensive sound attenuation parameter measurement result;
    输出设备,用于输出所述综合声衰减参数测量结果。The output device is used to output the measurement result of the comprehensive sound attenuation parameter.
PCT/CN2020/090336 2020-05-14 2020-05-14 Transient elasticity measurement method, acoustic attenuation parameter measurement method, and ultrasound imaging system WO2021226955A1 (en)

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