CN108720870A - A kind of fatty liver detecting system based on ultrasonic attenuation coefficient - Google Patents
A kind of fatty liver detecting system based on ultrasonic attenuation coefficient Download PDFInfo
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- CN108720870A CN108720870A CN201810855225.3A CN201810855225A CN108720870A CN 108720870 A CN108720870 A CN 108720870A CN 201810855225 A CN201810855225 A CN 201810855225A CN 108720870 A CN108720870 A CN 108720870A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5207—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of raw data to produce diagnostic data, e.g. for generating an image
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
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Abstract
The present invention is a kind of fatty liver detecting system based on ultrasonic attenuation coefficient, belongs to signal processing and liver attenuation coefficient technical field.Measure different degrees of Patients with Fatty Liver hepatic fat content, slave computer acquisition ultrasound echo signal is uploaded to host computer, gain first is carried out to original signal, bandpass filtering is carried out to signal again, remove interference noise, envelope detection is carried out using Hilbert transform pairs filtering signal, logarithmic transformation is carried out to the signal after detection again, obtain doing after data smothing filtering and down-sampled, linear fit is carried out to all continuity points and seeks straight slope, the final attenuation coefficient for acquiring corresponding data, the calculating process measures fat content in liver by calculating attenuation degree of the ultrasound echo signal in human liver's fat, it can be used for measuring the attenuation coefficient of liver organization and detect the degree of fatty liver.
Description
Technical field
The fatty liver detecting system based on ultrasonic attenuation coefficient that the present invention relates to a kind of, the system particularly relate to ultrasound
Method detects fatty attenuation coefficient to judge a kind of system of liver fat degree.
Background technology
Fatty liver (fatty liver) refer to due to various reasons caused by the excessive lesion of fat accumulation in liver cell,
It is a kind of common pathology of livers rather than a kind of independent disease.Fatty liver disease is just seriously threatening the health of compatriots, at
To be only second to the second largest hepatopathy of virus hepatitis, incidence is constantly increasing, and age of onset rejuvenation increasingly.Normal person liver
Contain a small amount of fat, such as triglycerides, phosphatide, glycolipid and cholesterol in tissue, weight be about liver weight 3%~
5%, if intrahepatic fat accumulation is too many, more than liver weight 5% or histologically 50% or more liver cell has steatosis
When, so that it may it is known as fatty liver.Its clinical manifestation less serious case is asymptomatic, and the severe one state of an illness is violent.In general, fatty liver category invertibity disease
Disease, early diagnosing and treating in time can often restore normal.
Making a definite diagnosis for previous fatty liver must rely on needle biopsy of liver, and this detection methods may be because of the generation of complication
Patient is often enabled to be difficult to receive.Apparent fatty liver is not difficult to obtain diagnosis according to ultrasound diagnosis, but morning, mid-term image not very allusion quotation
Type, although having, time point is finer and closely woven, does not occur the case where obvious Blood vessel pattern and far field echo are weakened, only according to
Discernable by eye is easily influenced by subjective factor, wants to make a definite diagnosis extremely difficult.
By area of computer aided ultrasound hepatic sclerosis detection device come quantitative detection hepatic fat content, it is used as diagnosing
A kind of detection means of fatty liver disease.The change of matter necessarily leads to quantitative change, and attenuation coefficient measurement is a dosing process, decaying
The height of coefficient directly reflects fat content.So attenuation coefficient can be quantified as one of Diagnosis of Fatty liver and indexing
Reference index.
Using attenuation coefficient is measured, it can effectively reflect its specific structure very sensitively according to tissue quality, density
Change, the case where to judge lesion, the deficiency for making up diasonograph.For large-scale crowd fatty liver screening with
And diagnosis, the treatment of mild fatty liver provide a kind of simple, accurate and effective diagnostic method.
Invention content
The present invention is a kind of fatty liver detecting system based on ultrasonic attenuation coefficient, belongs to signal processing and liver decaying system
Number technical field.Ultrasonic examination is non-invasive with its, without radiation insult, repeatability, it is cheap the advantages that, become primary dcreening operation fat
The prefered method of liver, so fatty attenuation coefficient can diagnose the content of liver fat as quantitative target.
Different degrees of Patients with Fatty Liver hepatic fat content is measured, slave computer acquisition ultrasound echo signal is uploaded to upper
Machine first carries out gain to original signal, then carries out bandpass filtering to signal, removes interference noise, utilizes Hilbert transform
Envelope detection is carried out to filtering signal, then logarithmic transformation is carried out to the signal after detection, obtain doing after data smothing filtering and
It is down-sampled, linear fit is carried out to all continuity points and seeks straight slope, finally acquires the attenuation coefficient of corresponding data, the calculating
Journey measures fat content in liver by calculating attenuation degree of the ultrasound echo signal in human liver's fat, can be used for surveying
It measures the attenuation coefficient of liver organization and detects the degree of fatty liver.
First aspect of the present invention it is proposed a kind of logarithmic transformation method for data compression, measures many cases difference journeys
Spend the hepatic fat content of Patients with Fatty Liver or body mould, the ultrasound echo signal that acquisition centre frequency is f, to ultrasound echo signal
It carries out gain and obtains original signal, to going the signal after gain to carry out bandpass filtering, to remove interference noise, then to signal
Envelope detection is carried out using Hilbert method, Log logarithmic transformations are done after modulus.
Another aspect of the present invention, it is proposed that a kind of smoothing method for data filtering, for every in data-signal
One row, do the smoothing processing of current point and preceding N-1 points since each column N points, the signal after obtaining smoothly.
Another aspect of the invention, it is proposed that a method of it is down-sampled for data, to it is above-mentioned it is smooth after signal into
Row down-sampled, each row in the number of winning the confidence, since starting point, every M points take a little obtain it is down-sampled after signal.
Fatty attenuation coefficient calculates simple in the present invention, can accomplish to measure in real time, assist existing B ultrasound equipment, curing
There is good behaviour in institute, medical center field application；The measurement of fatty attenuation coefficient is acquired by LeScan hepatic sclerosis detectors
Ultrasound echo signal carries out calculating verification, and result of calculation has very high accuracy；Ultrasonic examination is non-invasive with its, is damaged without radiation
The advantages that hindering, is repeatable, cheap, becomes the prefered method of primary dcreening operation fatty liver, so fatty attenuation coefficient can conduct
Quantitative target diagnoses the content of liver fat.
Description of the drawings
Attached drawing is used for providing further understanding the embodiment of the present invention herein, constitutes a part for the embodiment of the present invention,
But it is not limited to the present embodiment.In the accompanying drawings：
It is the overall flow figure of ultrasound echo signal processing of the present invention shown in Fig. 1
It is the flow chart that signal of the present invention carries out logarithmic transformation shown in Fig. 2
It is signal smoothing process chart of the present invention shown in Fig. 3
It is the down-sampled process chart of signal of the present invention shown in Fig. 4
Specific embodiment
Below in conjunction with the accompanying drawings, the embodiment of the present invention in further detail and completely illustrate, it is described herein specific
Embodiment is only used for explaining the embodiment of the present invention, rather than the restriction to the embodiment of the present invention.
In Fig. 1, it is shown that the signal processing flow figure of fatty attenuation coefficient is obtained by ultrasound echo signal, slave computer is adopted
Collection ultrasound echo signal is uploaded to host computer, first carries out gain to original signal, then carry out bandpass filtering to signal, removal is dry
Noise is disturbed, envelope detection is carried out using Hilbert transform pairs filtering signal, then logarithmic transformation is carried out to the signal after detection, obtains
Smothing filtering and down-sampled is done after to data, carrying out linear fit to all continuity points seeks straight slope, finally acquires correspondence
The attenuation coefficient of data.
In fig. 2, it is shown that the process flow of signal logarithmic transformation measures the different degrees of Patients with Fatty Liver of many cases or body mould
Hepatic fat content, acquisition centre frequency be f ultrasound echo signal, to ultrasound echo signal carry out gain obtain it is original
Signal, to going the signal after gain to carry out bandpass filtering, to remove interference noise, then to signal using Hilbert method into
Row envelope detection does Log transformation after modulus.
In figure 3, it is shown that signal smoothing process flow is done for each row in data-signal since each column N points
The smoothing processing of current point and preceding N-1 points, sum (data (i- (N-1)：I, line))/N.
In fig. 4 it is shown that signal down-sampled process flow, the signal after smooth is carried out it is down-sampled, in the number of winning the confidence
Each row, since starting point, every M points take a little obtain it is down-sampled after signal, data (M* (i-1)+1, line).
It is only presently preferred embodiments of the present invention, practical range not for the purpose of limiting the invention described in above example；It is i.e. all
The equivalents that right under this invention is done are that scope of the presently claimed invention is covered.
Claims (4)
1. a kind of fatty liver detecting system based on ultrasonic attenuation coefficient belongs to signal processing and liver attenuation coefficient technology neck
Domain.Ultrasonic examination is non-invasive with its, without radiation insult, repeatability, it is cheap the advantages that, become the first choice of primary dcreening operation fatty liver
Method, so fatty attenuation coefficient can diagnose the content of liver fat as quantitative target.It is characterized in that measuring different
Degree Patients with Fatty Liver hepatic fat content, slave computer acquisition ultrasound echo signal be uploaded to host computer, first to original signal into
Row goes gain, then carries out bandpass filtering to signal, removes interference noise, and envelope is carried out using Hilbert transform pairs filtering signal
Detection, then carry out logarithmic transformation to the signal after detection obtains doing after data smothing filtering and down-sampled, to all continuity points
It carries out linear fit and seeks straight slope, finally acquire the attenuation coefficient of corresponding data, the calculating process is by calculating ultrasonic echo
Attenuation degree of the signal in human liver's fat measures fat content in liver, can be used for measuring the decaying system of liver organization
The degree of number and detection fatty liver.
2. a kind of logarithmic transformation method for data compression according to claim 1, it is characterised in that measure many cases not
With degree Patients with Fatty Liver or the hepatic fat content of body mould, the ultrasound echo signal that acquisition centre frequency is f, to ultrasonic echo
Signal carries out gain and obtains original signal, then right to remove interference noise to going the signal after gain to carry out bandpass filtering
Signal carries out envelope detection using Hilbert method, and Log logarithmic transformations are done after modulus.
3. a kind of smoothing method for data filtering according to claim 1, it is characterised in that in data-signal
Each row, the smoothing processing of current point and preceding N-1 points is done since each column N points, obtain it is smooth after signal.
4. according to claim 1 a kind of for the down-sampled method of data, it is characterised in that it is above-mentioned it is smooth after letter
Number progress is down-sampled, each row in the number of winning the confidence, since starting point, every M points take a little obtain it is down-sampled after signal.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110313940A (en) * | 2019-08-01 | 2019-10-11 | 无锡海斯凯尔医学技术有限公司 | Signal decay calculation method, apparatus, equipment and computer readable storage medium |
| WO2021226955A1 (en) * | 2020-05-14 | 2021-11-18 | 深圳迈瑞生物医疗电子股份有限公司 | Transient elasticity measurement method, acoustic attenuation parameter measurement method, and ultrasound imaging system |
| RU2798784C1 (en) * | 2019-08-01 | 2023-06-27 | Уси Хиски Медикал Текнолоджис Ко., Лтд. | Method, apparatus and device for calculation of signal attenuation and machine-readable data carrier |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105930665A (en) * | 2016-04-26 | 2016-09-07 | 北京工业大学 | Liver fat qualitative measurement method based on ultrasonic attenuation coefficient |
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2018
- 2018-07-31 CN CN201810855225.3A patent/CN108720870A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105930665A (en) * | 2016-04-26 | 2016-09-07 | 北京工业大学 | Liver fat qualitative measurement method based on ultrasonic attenuation coefficient |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110313940A (en) * | 2019-08-01 | 2019-10-11 | 无锡海斯凯尔医学技术有限公司 | Signal decay calculation method, apparatus, equipment and computer readable storage medium |
| WO2021018102A1 (en) * | 2019-08-01 | 2021-02-04 | 无锡海斯凯尔医学技术有限公司 | Signal attenuation calculation method, signal attenuation calculation apparatus and signal attenuation calculation device, and computer-readable storage medium |
| RU2798784C1 (en) * | 2019-08-01 | 2023-06-27 | Уси Хиски Медикал Текнолоджис Ко., Лтд. | Method, apparatus and device for calculation of signal attenuation and machine-readable data carrier |
| WO2021226955A1 (en) * | 2020-05-14 | 2021-11-18 | 深圳迈瑞生物医疗电子股份有限公司 | Transient elasticity measurement method, acoustic attenuation parameter measurement method, and ultrasound imaging system |
| CN114144119A (en) * | 2020-05-14 | 2022-03-04 | 深圳迈瑞生物医疗电子股份有限公司 | Instantaneous elasticity measurement method, acoustic attenuation parameter measurement method and ultrasonic imaging system |
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Application publication date: 20181102 |