WO2021225949A1 - Système et procédé de capture et de conservation de fluide corporel - Google Patents

Système et procédé de capture et de conservation de fluide corporel Download PDF

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Publication number
WO2021225949A1
WO2021225949A1 PCT/US2021/030449 US2021030449W WO2021225949A1 WO 2021225949 A1 WO2021225949 A1 WO 2021225949A1 US 2021030449 W US2021030449 W US 2021030449W WO 2021225949 A1 WO2021225949 A1 WO 2021225949A1
Authority
WO
WIPO (PCT)
Prior art keywords
collection jar
plunger
phase change
change material
disposed
Prior art date
Application number
PCT/US2021/030449
Other languages
English (en)
Inventor
Thomas Smith
Pepin Gelardi
Theodore Ullrich
Ross Sloan
Original Assignee
Dadi Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/865,577 external-priority patent/US11707407B2/en
Application filed by Dadi Inc. filed Critical Dadi Inc.
Publication of WO2021225949A1 publication Critical patent/WO2021225949A1/fr

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
    • B01L3/5055Hinged, e.g. opposable surfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0621Control of the sequence of chambers filled or emptied
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16Reagents, handling or storing thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/18Transport of container or devices
    • B01L2200/185Long distance transport, e.g. mailing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/02Identification, exchange or storage of information
    • B01L2300/021Identification, e.g. bar codes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/043Hinged closures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • B01L2300/047Additional chamber, reservoir
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons

Definitions

  • the present invention involves a system and method for capturing and preserving a bodily fluid. More particularly, the present invention involves a system and method for capturing, preserving, and transporting a bodily fluid, such as semen ejaculate, for short or long term storage, subsequent use in in vitro fertilization or other medical procedures and/or testing. Simplicity of use is an important element of the invention as it is intended to be primarily used by ordinary consumers and preservation of the sample is critical.
  • spermatozoa i.e., sperm or sperm cells
  • Current means of storing spermatozoa typically involve a remote site for on-premise collection of the specimen, such as at a sperm bank or cryobank.
  • the interested male must travel to this facility, masturbate while there, and travel back home once finished. This can be time-consuming and uncomfortable, as the interested male must essentially masturbate on command in addition to the facility likely having an unappealing sterile medical ambience. It would be preferable for the interested male to be able to collect the specimen in the comfort of his home and at his leisure.
  • kits have been recently developed and available for interested males. However, these kits either have no or poor temperature control elements, such as dry ice packs or cold packs, for maintaining the kit and/or the specimen at an acceptable temperature range or below a maximum.
  • temperature control elements such as dry ice packs or cold packs
  • kits also include numerous components, requiring much more labor and handling by the user and, consequently, leading to greater human error. Therefore, there exists a need for a system and associated method of at-home specimen collection with superior ease of use and precise transportation temperature control.
  • the invention features a system for capturing, preserving, and transporting a bodily fluid, including a collection jar having a base body, a lid body configured to attach to the base body to close the collection jar, and a cartridge having a plunger therein and disposed in the lid body, the cartridge housing a preservative when the plunger is in a first plunger position and permitting a release of the preservative into an internal cavity of the collection jar when the plunger is in a second plunger position, where the plunger is configured to move from the first plunger position to the second plunger position by pushing the plunger into the internal cavity, and a transportation packaging having an outer container, at least one insulation foam support disposed in the outer container, at least one phase change material bottle disposed in the outer container, and at least one collection jar holding tray disposed in the outer container, where the phase change material bottle has an indented portion corresponding to an indented portion of the collection jar holding tray, and where the collection jar is configured for placement in the at least
  • Implementations of the invention may include one or more of the following features.
  • the collection jar may further include a threaded attachment mechanism configured to screw the lid body onto the base body to close the collection jar.
  • the preservative may be a commercially available medium including gentamicin, glycerol, and/or albumin.
  • the at least one insulation foam support may include a polyurethane foam.
  • the at least one phase change material bottle may include a phase change material, and the phase change material may be a commercially available phase change material including a functionalized bioPCM, an inorganic material, an organic material, and/or a eutectic material.
  • the transportation packaging may further include at least one absorbent layer.
  • the transportation packaging may include two insulation foam supports, two phase change material bottles, and two collection jar holding trays.
  • the outer container may be a hinged box having a first half and a second half, where each of the first half and the second half includes one insulation foam support, one phase change material bottle, and one collection jar holding tray.
  • the transportation packaging may include an internal device disposed therein and having a first two-factor authentication code, and an external device disposed thereon and having a second two-factor authentication code, the external device being in the form of a seal.
  • the transportation packaging may be configured to maintain a mixture of the bodily fluid and the preservative at a temperature in the range of 15 to 37 degrees Centigrade.
  • the invention features a method of capturing, preserving, and transporting a bodily fluid, including placing a bodily fluid in an internal cavity of a collection jar, closing the collection jar with the bodily fluid disposed therein, releasing a preservative into the internal cavity of the collection jar, and placing the collection jar with the bodily fluid and released preservative disposed therein into a transportation packaging
  • the collection jar includes a base body, a lid body configured to attach to the base body to close the collection jar, and a cartridge having a plunger therein and disposed in the lid body, the cartridge housing a preservative when the plunger is in a first plunger position and permitting a release of the preservative into an internal cavity of the collection jar when the plunger is in a second plunger position, where the plunger moves from the first plunger position to the second plunger position by pushing the plunger into the internal cavity
  • the transportation packaging includes an outer container, at least one insulation foam support disposed in the outer container,
  • Implementations of the invention may include one or more of the following features.
  • the collection jar may further include a threaded attachment mechanism configured to screw the lid body onto the base body to close the collection jar.
  • the preservative may be a commercially available medium including gentamicin, glycerol, and/or albumin.
  • the at least one insulation foam support may include a polyurethane foam.
  • the at least one phase change material bottle may include a phase change material, and the phase change material may be a commercially available phase change material including a functionalized bioPCM, an inorganic material, an organic material, and/or a eutectic material.
  • the transportation packaging may further include at least one absorbent layer.
  • the transportation packaging may include two insulation foam supports, two phase change material bottles, and two collection jar holding trays.
  • the outer container may be a hinged box having a first half and a second half, where each of the first half and the second half includes one insulation foam support, one phase change material bottle, and one collection jar holding tray.
  • the transportation packaging may include an internal device disposed therein and having a first two-factor authentication code, and an external device disposed thereon and having a second two-factor authentication code, the external device being in the form of a seal.
  • the transportation packaging may maintain a mixture of the bodily fluid and the preservative at a temperature in the range of 15 to 37 degrees Centigrade.
  • Fig 1A shows a front perspective exploded view of a collection jar of one embodiment of the present invention
  • Fig. IB shows a front perspective view of the collection jar of Fig. 1 A;
  • Fig. 1C shows a side view of the collection jar of Fig. 1A
  • Fig. ID shows a top view of the collection jar of Fig. 1A
  • Fig. 2A shows a front perspective exploded view of a collection jar cartridge of one embodiment of the present invention
  • Fig. 2B shows a side cross-sectional view of the collection jar cartridge of Fig. 2A;
  • Fig 3 A shows a front perspective exploded view of a collection jar transportation packaging of one embodiment of the present invention
  • Fig. 3B shows a front perspective view of the collection jar transportation packaging of Fig. 3 A;
  • Fig. 3C shows a side view of the collection jar transportation packaging of Fig. 3 A;
  • Fig. 3D shows a top view of the collection jar transportation packaging of Fig. 3A
  • Fig. 4A shows a front perspective view of a system of one embodiment of the present invention, the system including a collection jar and a collection jar transportation packaging;
  • Fig. 4B shows a front perspective exploded view of the system of Fig. 4A;
  • Fig. 4C shows a front perspective exploded view of the collection jar of the system of
  • FIG. 4A shows a front perspective exploded view of a portion of the collection jar transportation packaging of the system of Fig. 4A;
  • Fig. 5 A shows aspects of a two-factor authentication code system utilized in connection with a collection jar of the present invention.
  • Fig. 5B shows aspects of the two-factor authentication code system utilized in connection with a collection jar transportation packaging of the present invention.
  • the present invention relates to a system and associated method for capturing, preserving, and transporting a bodily fluid, including through the use of a collection jar, an associated sealing lid and a transportation packaging, as will be described herein.
  • the collection jar is preferably configured to collect and hold the bodily fluid and a wash solution which may include a short and/or long term specimen preservative.
  • the collection jar is also preferably configured to easily release the wash solution/preservative into the internal cavity of the jar, such as by a simple push button mechanism.
  • the transportation packaging is preferably configured to hold the collection jar in a sufficiently stable position during transportation, both to and from a user and the laboratory for testing and short and long term storage facility.
  • the transportation packaging is also preferably configured to maintain the specimen, as preserved, in the collection jar within an acceptable temperature range, preferably but not exclusively between 15 to 37 degrees Centigrade.
  • the overall process may cover transporting the collection jar in a transportation packaging to a user, removing the collection jar from the transportation packaging, depositing a bodily fluid in the collection jar, releasing the preservative, and transporting the filled collection jar in the transportation packaging to another location, such as a testing laboratory or storage facility.
  • the bodily fluid is semen ejaculate.
  • Figs. 1-4 show different views of systems of several embodiments of the present invention.
  • a system 1 includes a collection jar 100 and a transportation packaging 200. Collection jar 100 may be disposed within, and removed from, transportation packaging 200. The collection jar 100 is meant to be centrally housed within the transportation packaging 200.
  • components of collection jar 100 include abase body 110, a lid body 120 that attaches to base body 110 via mating screw threads on internal container body lll.
  • a threaded attachment mechanism may be included in collection jar 100 to permit lid body 120 to screw onto base body 110 and internal container body 111 to open and close jar 100.
  • a cartridge 112 including plunger button 130 on cartridge body 122 is disposed within lid body 120, with plunger buton 130 being exposed through an opening in lid body 120.
  • the base body 110 with internal container body 111 includes a central holding area, similar to many cosmetic holding jars, now commercially available.
  • the lid body 120 mates and closes off the interior of the collection jar. In the exploded view of Fig.
  • collection jar 100 includes base body 110 and an internal container body 111 that connects with base body 110. Internal container body 111 snaps or screws into the base body 110 and provides a central depression area for the specimen. Collection jar 100 also includes outer lid body 120 and cartridge 112, described in greater detail with regards to Fig. 2.
  • components of collection jar cartridge 112 include a cartridge body 122, an internal container seal 121, plunger buton 130, a plunger 132, a plunger plug 133, and a plunger endcap 134.
  • Fig. 2B is a cross-sectional view of collection jar cartridge 112.
  • Cartridge 112 may house a substance, such as a wash solution, a preservative, a wash solution containing a preservative, and the like.
  • the substance may include one or more preservatives, nutrients, and/or other compounds for maintaining the health of the bodily fluid for several days, including through return transportation.
  • a selected preservative may be a commercially available medium, such as those including gentamicin, glycerol, and/or albumin, and/or such as those produced by IRVINE SCIENTIFIC (e g., MULTIPURPOSE HANDLING MEDIUM), VITROLIFE (e g., SPERMRINSE), COOPERSURGICAL, VETOQUINOL, THERMOFISHER SCIENTIFIC (e.g., Gibco Cell Culture Media), and the like.
  • IRVINE SCIENTIFIC e g., MULTIPURPOSE HANDLING MEDIUM
  • VITROLIFE e g., SPERMRINSE
  • COOPERSURGICAL e.g., VETOQUINOL
  • THERMOFISHER SCIENTIFIC e.g., Gibco Cell Culture Media
  • the substance may be loaded into cartridge 112 through the use of a circular jig, particularly a circular jig in which cartridge body 122 may sit inverted with plunger plug 133 having been removed such that the substance may be added into the central opening available by the removal of plug 133 and sealed therein by the reinsertion of plug 133.
  • a user may collect his or her bodily fluid in collection jar 100, such as onto the depression in internal container body 111, and close collection jar 100, such as by screwingly attaching lid body 120 to base body 110.
  • the user may elect to release the preservative or wash substance housed in cartridge 112.
  • the user may press or push plunger button 130 to move plunger 132 from the first position to a second position, i.e., the depressed position.
  • the plunger is in the second position, an internal cavity of cartridge 112 is in fluid communication, i.e., opened to, the depression of the internal container body 111.
  • the internal cavity of collection jar 100 such as internal container body 111, and the preservative substance, may secrete from cartridge 112 and into the internal cavity of collection jar 100, thereby mixing with the bodily fluid disposed therein.
  • the substance-release mechanism is irreversible, i.e., plunger button 130 can only be pressed once and plunger 132 cannot be reversed from the second plunger position back to the original first plunger position.
  • Fig. 3 shows an exploded view of a transportation packaging 200.
  • transportation packaging 200 includes a first outer container part 211 and a second outer container part 212, which together form the outer container, such as one in the form of a hinged box, optionally including a locking mechanism such as latch 213.
  • transportation packaging 200 includes a first assembly disposed in first outer container part 211 that is formed of an insulation foam 221, phase change material bottle 231, and collection jar holding tray 251.
  • transportation packaging 200 includes a second assembly disposed in second outer container part 212 that is formed of an insulation foam 222, phase change material bottle 232, and collection jar holding tray 252.
  • Absorbent layers may be included beneath collection jar holding tray 252, such as jar containment absorbent layer 241 and tray absorbent layer 242.
  • Tray 252 may include a plurality of small holes to permit any spillage to exit tray 252 and be absorbed by the absorbent layers.
  • the absorbent layers are preferably foam with a capacity to absorb more than 20 mL of spillage.
  • a wiper gasket 262 may be included in connection with collection jar holding tray 252, with gasket retainer 261 being utilized for securing gasket 262 to tray 252.
  • Collection jar holding trays 251 and 252 are preferably configured to hold or cradle, including during transportation, collection jar 100 within a centrally recessed or indented portion of trays 251 and 252.
  • Phase change material bottles 231 and 232 may also have a corresponding centrally recessed or indented portion such that indented portions of trays 251 and 252 are disposed in indented portions of phase change material bottles 231 and 232, respectively.
  • Insulation foam 221 and 222 may have a central opening. This shape permits phase change material bottles 231 and 232 to be surrounded by, or sit in, insulation foam 221 and 222, thereby eliminating or reducing thermal leakage at side portions and slowing down heat transfer between the ambient environment and the phase change material.
  • Acceptable types of foam for utilization as the foam insulation include polyurethane foam and other foams having low density and low thermal conductivity.
  • phase change material is preferably disposed in phase change material bottles 231 and 232, and the selected phase change material may be a commercially available phase change material, including but not limited to a functionalized bioPCM, an inorganic material, an organic material, a eutectic material. Examples include SAVENRG PCM-OM18P (RGEES, LLC), SAVENRG PCM-HS22P (RGEES, LLC), and the like.
  • the phase change material be selected such that both the preservative first housed in collection j ar 100 as well as the bodily fluid-preservative mixture subsequently housed in collection jar 100 are maintained at a desired temperature, such as a temperature in the range of 15 to 37 degrees Centigrade, during transportation.
  • the desired temperature range may be any acceptable temperature range and may be determined based on the substance or object being housed and transported as well as the associated phase change material selected for this substance or object.
  • the system is capable of maintaining the bodily fluid-preservative mixture at a temperature above 15 degrees Centigrade for more than 30 hours in an ambient temperature of 7 degrees Centigrade and for more than 12 hours in an ambient temperature of 15 degrees Centigrade.
  • Fig. 4 shows a system 1 according to one embodiment of the present invention.
  • Figs. 4A-4B show system 1 including collectionjar 100, collection jar transportation packaging 200, and associated components, including those previously described.
  • Fig. 4C shows collection jar 100 and associated components of this embodiment.
  • Fig. 4D shows a portion of collection jar transportation packaging 200, particularly that portion which includes insulation foam 222.
  • While a primary application of the system and associated method of the present invention is the collection and transportation of semen ejaculate, this system and method may be utilized with respect to other bodily fluids that can be collected through home use and that benefit from greater temperature control during transportation, either to or from the user.
  • Other bodily fluids and the like may include amniotic fluid, aqueous humour, vitreous humour, bile, blood, blood plasma, blood serum, cerebrospinal fluid, cerumen or earwax, chyle, chyme, endolymph, perilymph, exudates, feces, female ejaculate, gastric acid, gastric juice, lymph, mucus, pericardial fluid, peritoneal fluid, pleural fluid, pus, rheum, saliva, sebum or skin oil, serous fluid, semen, serum, smegma, sputum, synovial fluid, sweat, tears, urine, vaginal secretion, vaginal discharge, vomit, cord blood, and stem cells.
  • this system and method may be utilized in non-human applications, e.g., for animal bodily fluids, including but not limited to horse or bull semen. Additionally, this system and method may be utilized in non-medical applications involving multiple transportations with a need for greater temperature control, such as meats, beverages, and luxury goods at risk of damage by extreme temperatures.
  • Fig. 5A illustrates aspects of a two-factor authentication code known by the ERP system that is utilized in connection with collection jar 100, specifically QR code 501 and numeric code 502 disposed on collection jar 100.
  • Fig. 5B illustrates aspects of the two- factor authentication code known by the ERP system that is utilized in connection with transportation packaging 200, specifically seal 510 having barcode 511 disposed thereon.
  • Seal 510 may be originally packaged in an open position within transportation packaging 200 when being transported to a user. Upon the user preparing to return or further transport transportation packaging 200 having collection jar 100 disposed therein, the user may seal transportation packaging 200 with seal 510 at portions thereon, including but not limited to clasps, loops, hooks, and the like arranged on transportation packaging 200. A preferred embodiment is the inclusion of two hardened clasps on transportation packaging 200 capable of holding the user- applied seal in place.
  • the ERP system is configured to match the known codes. Codes may be scanned and paired to authenticate the substances at one or more times in the transportation process, including prior to transit, after transit to the user, and/or after transit from the user.
  • the authentication system of the present invention is not limited to the embodiment of Fig.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Packages (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

L'invention concerne un système et un procédé associé pour la capture, la conservation, et le transport d'un fluide corporel, comprenant un pot de collecte ayant un corps de base, un corps de couvercle, et une cartouche renfermant un piston et disposée dans le corps de couvercle, la cartouche contenant un agent de conservation lorsque le piston est dans une première position de piston et permettant une libération de l'agent de conservation dans une cavité interne du pot de collecte lorsque le piston est dans une seconde position de piston, et un emballage de transport ayant un récipient externe, au moins un support de mousse isolant, au moins une bouteille de matériau à changement de phase, et au moins un plateau de maintien de pot de collecte, la bouteille de matériau à changement de phase ayant une partie en retrait correspondant à une partie en retrait du plateau de maintien de pot de collecte, et le pot de collecte étant conçu pour être placé dans ledit au moins un plateau de maintien de pot de collecte pendant le transport.
PCT/US2021/030449 2020-05-04 2021-05-03 Système et procédé de capture et de conservation de fluide corporel WO2021225949A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16/865,577 US11707407B2 (en) 2018-11-20 2020-05-04 System and method for bodily fluid capture and preservation
US16/865,577 2020-05-04

Publications (1)

Publication Number Publication Date
WO2021225949A1 true WO2021225949A1 (fr) 2021-11-11

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Application Number Title Priority Date Filing Date
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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4530816A (en) * 1983-06-15 1985-07-23 Hamilton Farm Method and device for cooling, preserving and safely transporting biological material
FR2650256A1 (fr) * 1989-07-27 1991-02-01 Marcoux Jean Container isothermique pour le transport sans choc thermique et sans vibration de semences animales destinees a l'insemination artificielle, procede pour la mise en temperature d'insemination de l'ejaculat ainsi transporte et sperme ainsi obtenu
US20060254944A1 (en) * 2005-05-10 2006-11-16 Yi-Feng Kao Dehydration and preservation method for a sanitary utensil containing bio-specimen and the storage device thereof
WO2009123889A1 (fr) * 2008-03-29 2009-10-08 Cohen B Ariel Dispositif pour optimiser la qualité du sperme
US20100137741A1 (en) * 2008-12-01 2010-06-03 Oasis Diagnostics Corporation Multi compartment body part scraping fluid collection device
US20120310113A1 (en) * 2008-12-01 2012-12-06 Oasis Diagnostics Corporation Biological sample collection system
US20130091890A1 (en) * 2010-06-28 2013-04-18 Biocision, Llc Specimen freezing rate regulator device
US20170000109A1 (en) * 2015-07-02 2017-01-05 Xiaojun Xing Multilayer insulation of biological samples and cooling by immersing in a cryogenic liquid for cryopreservation
US20200155126A1 (en) * 2018-11-20 2020-05-21 Project Legacy, Inc. System and method for bodily fluid capture and preservation

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4530816A (en) * 1983-06-15 1985-07-23 Hamilton Farm Method and device for cooling, preserving and safely transporting biological material
FR2650256A1 (fr) * 1989-07-27 1991-02-01 Marcoux Jean Container isothermique pour le transport sans choc thermique et sans vibration de semences animales destinees a l'insemination artificielle, procede pour la mise en temperature d'insemination de l'ejaculat ainsi transporte et sperme ainsi obtenu
US20060254944A1 (en) * 2005-05-10 2006-11-16 Yi-Feng Kao Dehydration and preservation method for a sanitary utensil containing bio-specimen and the storage device thereof
WO2009123889A1 (fr) * 2008-03-29 2009-10-08 Cohen B Ariel Dispositif pour optimiser la qualité du sperme
US20100137741A1 (en) * 2008-12-01 2010-06-03 Oasis Diagnostics Corporation Multi compartment body part scraping fluid collection device
US20120310113A1 (en) * 2008-12-01 2012-12-06 Oasis Diagnostics Corporation Biological sample collection system
US20130091890A1 (en) * 2010-06-28 2013-04-18 Biocision, Llc Specimen freezing rate regulator device
US20170000109A1 (en) * 2015-07-02 2017-01-05 Xiaojun Xing Multilayer insulation of biological samples and cooling by immersing in a cryogenic liquid for cryopreservation
US20200155126A1 (en) * 2018-11-20 2020-05-21 Project Legacy, Inc. System and method for bodily fluid capture and preservation

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