WO2021224481A1 - Désinfectant pour les mains - Google Patents

Désinfectant pour les mains Download PDF

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Publication number
WO2021224481A1
WO2021224481A1 PCT/EP2021/062206 EP2021062206W WO2021224481A1 WO 2021224481 A1 WO2021224481 A1 WO 2021224481A1 EP 2021062206 W EP2021062206 W EP 2021062206W WO 2021224481 A1 WO2021224481 A1 WO 2021224481A1
Authority
WO
WIPO (PCT)
Prior art keywords
weight
disinfectant according
hand disinfectant
hand
alcohol
Prior art date
Application number
PCT/EP2021/062206
Other languages
German (de)
English (en)
Inventor
Alain GIGER
Original Assignee
Giger & Klingler Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giger & Klingler Ag filed Critical Giger & Klingler Ag
Publication of WO2021224481A1 publication Critical patent/WO2021224481A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N3/00—Preservation of plants or parts thereof, e.g. inhibiting evaporation, improvement of the appearance of leaves or protection against physical influences such as UV radiation using chemical compositions; Grafting wax
    • A01N3/02—Keeping cut flowers fresh chemically
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02—Acyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/242—Gold; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Definitions

  • the present invention relates to a hand disinfectant having the features of the preamble of claim 1, comprising 50 to 95% by weight of an alcohol and made up to 100% by weight with water.
  • disinfectants consist of a mixture of a high concentration alcohol and water.
  • Various approaches have been attempted to improve skin friendliness, to increase the service life of more complex mixtures, to simplify their production, etc.
  • WO 2018/114121 A1 discloses a disinfectant consisting of: (i) an antimicrobial particulate composite material comprising an oligodynamic metal which is embedded in a water-insoluble inorganic carrier; and (ii) at least one of thymol or terpineol or a mixture thereof.
  • CN111085492A discloses a multifunctional medical instrument cleaning device comprising a cleaning tank body, a clamp assembly and movable means, said cleaning tank being fixedly mounted within the sterilization box body.
  • the box body is provided with a water spray cleaner which includes a spray tube, a water tank and a water pump. These are connected to each other by hoses with a gold wire connection, which improves the disinfection process, the efficiency of the work and at the same time the safety of the medical staff.
  • the post-published WO2020 / 092703A discloses various methods for cleaning automated circulatory systems or devices that generate wastewater suitable for irrigation.
  • a disinfectant or a fungicide can be used may be used, which contains surface plasmon resonance particles (PRPs) and resonance light scattering particles (RLSs) - particles of silver or gold that scatter light.
  • PRPs surface plasmon resonance particles
  • RLSs resonance light scattering particles
  • the size and shape of the PRP / RLS particles determine the wavelength of the scattered light).
  • the invention is based on the object of specifying a hand disinfectant which retains a disinfecting effect that continues to have a disinfectant effect even after it has been applied.
  • Another object of the invention is to automatically restore the sun protection for the hands and wrists that is no longer present after hand disinfection.
  • oligodynamic metals are added to the mixture known from the preamble, these corresponding to between 0.01% by weight and 1.0% by weight of the prepared hand disinfectant.
  • oligodynamic metals are preferably added in the amount of 0.1 g to 1 g per 15 cl.
  • Metals of the 8th to 11th groups of the 5th and 6th periods of the periodic table of the elements are added as oligodynamic metals, either in the form of a single metal or a mixture of different metals.
  • the oligodynamic metals are mixed in in particular in powder form.
  • this can be added as a 24 carat powder with grain sizes from 300 to 900 microns, especially 400, 425 or 600 microns.
  • the product Due to the catalytic effect of the oligodynamic metals, the product will lose its liquid components more quickly and develop a leave-on character.
  • the remaining metallic components reflect the sun's rays and leave especially UV radiation does not penetrate the skin. There is also a shiny effect on the skin, which shows the protective effect.
  • a sparkling powder mixture of 1% by weight to 5% can be added, which consists in particular of sodium borosilicate glass or calcium-sodium borosilicate glass and titanium dioxide, whereby the borosilicate glass is preferably between 92 Wt .-% to 97 wt .-% and the titanium dioxide essentially makes up the remainder of the mixture.
  • composition of the present invention is preferably in the form of a "leave-on" composition.
  • the leave-on composition can be in the form of a disappearing cream or in the form of a disinfectant composition.
  • the preferred application is hand disinfection with evaporating liquid ingredients.
  • the cosmetically acceptable base consists of alcohol and water.
  • the preferred alcohols are ethyl alcohol and isopropyl alcohol.
  • a mixture of two or more alcohols can also preferably be used in the hand sanitizer composition.
  • the amount of alcohol should preferably be in the range of 50 wt% to 95 wt%, more preferably 60 wt% to 80 wt%, and most preferably 65 wt% to 80 wt% of the weight of the Hand sanitizer composition lying.
  • the hand disinfectant preferably contains 7,7-trimethylbicyclo [2.2.1] -2-heptanone in a proportion of 0% to 0.2% by weight, in particular 0.1% by weight.
  • Other names are camphor or (+) - Bornan-2-one.
  • the hand disinfectant preferably contains 2-amino-2-methylpropanol in a proportion of 0% to 0.1% by weight, in particular 0.04% by weight.
  • ingredients can be glycerine as a denaturant, humectant, perfume, and part of the solvent; Chamomile flower extract for skin care; Leaf extract of the Virginian witch hazel also for skin care, panthenol as an antistatic skin care additive; Allantoin as a skin-caring, skin-protecting and soothing additive with regard to the disinfecting substances. (-) - a-Bisabolol should also be added as a further skin care and skin calming additive.
  • Acrylate / c10-30 alkyl acrylate cross-polymer can be added for emulsion stabilization, film formation and viscosity control. As a product that is not easily degradable, it can be dispensed with in other formulations in favor of other stabilizers.
  • PEG-12 dimethicone can be added as a conditioning agent.
  • An addition of sodium hydroxide can serve as a buffering agent.
  • the pH value of the disinfectant can be set to values between 7.1 and 7.5.
  • H2O water
  • the advantages of adding several oligodynamic metals lies in the interaction of the different ingredients:
  • the silver component increases the disinfection aspect of the suspension; the gold content leads to interactions of the upper skin layers to an anti-aging effect and according to the applicant, platinum interacts with the nervous system.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Emergency Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Organic Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention se rapporte à un désinfectant pour les mains comprenant de 50 % en pds à 95 % en pds d'un alcool, un ou plusieurs métaux oligodynamiques ayant 0,01 % en pds et 1,0 % en pds, et de l'eau. En particulier, des métaux du 8ᵉ au 11ᵉ groupe de la 5ᵉ et 6ᵉ période du tableau périodique des éléments sont utilisés, de préférence à partir du groupe comprenant l'argent, l'or, le platine, et l'osmium. De plus, l'invention concerne un mélange pulvérulent de verre borosilicate et de dioxyde de titane. En particulier, le désinfectant pour les mains est conçu pour améliorer l'hygiène des mains, fournir une protection contre le soleil, et afficher l'état de protection de ces deux fonctions.
PCT/EP2021/062206 2020-05-07 2021-05-07 Désinfectant pour les mains WO2021224481A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH00550/20 2020-05-07
CH00550/20A CH717395A2 (de) 2020-05-07 2020-05-07 Handdesinfektionsmittel.

Publications (1)

Publication Number Publication Date
WO2021224481A1 true WO2021224481A1 (fr) 2021-11-11

Family

ID=76181068

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2021/062206 WO2021224481A1 (fr) 2020-05-07 2021-05-07 Désinfectant pour les mains

Country Status (2)

Country Link
CH (1) CH717395A2 (fr)
WO (1) WO2021224481A1 (fr)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1506772A2 (fr) * 2003-08-13 2005-02-16 L'oreal Filtres solaires UV à aspect et SPF améliorés qui comprennent des microsphères en verre
CA2587064A1 (fr) * 2007-05-02 2008-11-02 Savon Roby Inc. Gel antimicrobien pour la peau
PL211394B1 (pl) * 2007-01-30 2012-05-31 Nanoco Społka Z Ograniczoną Odpowiedzialnością Preparat biobójczy
WO2018114121A1 (fr) 2016-12-20 2018-06-28 Unilever N. V. Composition antimicrobienne comprenant un métal oligodynamique
JP2020019746A (ja) * 2018-08-03 2020-02-06 株式会社大阪製薬 粘稠抗菌剤
CN111085492A (zh) 2019-12-31 2020-05-01 詹碧容 一种多功能医疗用器械清洗装置
WO2020092703A1 (fr) 2018-10-31 2020-05-07 Diversey, Inc. Procédés de nettoyage de systèmes de recirculation automatisés et utilisation d'un effluent de déchets généré à partir de ceux-ci

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1506772A2 (fr) * 2003-08-13 2005-02-16 L'oreal Filtres solaires UV à aspect et SPF améliorés qui comprennent des microsphères en verre
PL211394B1 (pl) * 2007-01-30 2012-05-31 Nanoco Społka Z Ograniczoną Odpowiedzialnością Preparat biobójczy
CA2587064A1 (fr) * 2007-05-02 2008-11-02 Savon Roby Inc. Gel antimicrobien pour la peau
WO2018114121A1 (fr) 2016-12-20 2018-06-28 Unilever N. V. Composition antimicrobienne comprenant un métal oligodynamique
JP2020019746A (ja) * 2018-08-03 2020-02-06 株式会社大阪製薬 粘稠抗菌剤
WO2020092703A1 (fr) 2018-10-31 2020-05-07 Diversey, Inc. Procédés de nettoyage de systèmes de recirculation automatisés et utilisation d'un effluent de déchets généré à partir de ceux-ci
CN111085492A (zh) 2019-12-31 2020-05-01 詹碧容 一种多功能医疗用器械清洗装置

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
.: "Gold Strike / Silver Strike", 1 January 2000 (2000-01-01), Amsterdam, Netherlands, pages 1 - 1, XP055831721, Retrieved from the Internet <URL:https://www.maxxium.nl/merken/gold-strike-silver-strike/> [retrieved on 20210812] *
CHRISTINA L BURNETT ET AL: "Final amended report on safety assessment on aminomethyl propanol and aminomethyl propanediol", INTERNATIONAL JOURNAL OF TOXICOLOGY, SAGE PUBLICATIONS, INC, US, vol. 28, no. 65, 1 January 2009 (2009-01-01), pages 141S - 161S, XP008160925, ISSN: 1091-5818, DOI: 10.1177/1091581809350932 *
DATABASE GNPD [online] MINTEL; 23 July 2020 (2020-07-23), ANONYMOUS: "Hand Sanitizer Spray", XP055831857, retrieved from https://www.gnpd.com/sinatra/recordpage/7973985/ Database accession no. 7973985 *
DATABASE GNPD [online] MINTEL; 4 February 2021 (2021-02-04), ANONYMOUS: "Alcohol Hand Gel", XP055831854, retrieved from https://www.gnpd.com/sinatra/recordpage/8462313/ Database accession no. 8462313 *
HANS E MÜLLER: "Untersuchungen zur oligodynamischen Wirkung von 17 verschiedenen Metallen auf Bacillus subtilis, Enterobacteriaceae, Legionellaceae, Micrococcaceae und Pseudomonas aeruginosa", ZENTRALBLATT FÜR BAKTERIOLOGIE UND HYGIENE, SEKTION B, vol. 182, 1 December 1985 (1985-12-01), Germany, pages 95 - 101, XP009529342 *
TILAKI R M ET AL: "The effect of liquid environment on size and aggregation of gold nanoparticles prepared by pulsed laser ablation", JOURNAL OF NANOPARTICLE RESEARCH ; AN INTERDISCIPLINARY FORUM FOR NANOSCALE SCIENCE AND TECHNOLOGY, KLUWER ACADEMIC PUBLISHERS, DO, vol. 9, no. 5, 23 September 2006 (2006-09-23), pages 853 - 860, XP019506663, ISSN: 1572-896X *

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