WO2021221588A1 - Système d'analyse de couleur d'un échantillon d'urine - Google Patents

Système d'analyse de couleur d'un échantillon d'urine Download PDF

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Publication number
WO2021221588A1
WO2021221588A1 PCT/TR2021/050389 TR2021050389W WO2021221588A1 WO 2021221588 A1 WO2021221588 A1 WO 2021221588A1 TR 2021050389 W TR2021050389 W TR 2021050389W WO 2021221588 A1 WO2021221588 A1 WO 2021221588A1
Authority
WO
WIPO (PCT)
Prior art keywords
urine
analysis system
color analysis
monitoring line
camera
Prior art date
Application number
PCT/TR2021/050389
Other languages
English (en)
Inventor
Utku ULUSAHIN
Ali Agulcan DULGER
Ahmet ULUDAG
Original Assignee
Oruba Medikal Teknoloji Arge Ic Ve Dis Tic. Ltd. Sti.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oruba Medikal Teknoloji Arge Ic Ve Dis Tic. Ltd. Sti. filed Critical Oruba Medikal Teknoloji Arge Ic Ve Dis Tic. Ltd. Sti.
Publication of WO2021221588A1 publication Critical patent/WO2021221588A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/207—Sensing devices adapted to collect urine
    • A61B5/208—Sensing devices adapted to collect urine adapted to determine urine quantity, e.g. flow, volume
    • E—FIXED CONSTRUCTIONS
    • E03—WATER SUPPLY; SEWERAGE
    • E03D—WATER-CLOSETS OR URINALS WITH FLUSHING DEVICES; FLUSHING VALVES THEREFOR
    • E03D11/00—Other component parts of water-closets, e.g. noise-reducing means in the flushing system, flushing pipes mounted in the bowl, seals for the bowl outlet, devices preventing overflow of the bowl contents; devices forming a water seal in the bowl after flushing, devices eliminating obstructions in the bowl outlet or preventing backflow of water and excrements from the waterpipe
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B10/007—Devices for taking samples of body liquids for taking urine samples

Definitions

  • This invention relates to a urine sample color analysis system that allows visual tests to be carried out using a camera in order to find out current medical condition of an individual from the urine samples.
  • the urine color analysis is performed in two main ways. The first and most common of these is that after the sample is transferred to a container by a patient, the analysis is performed in a laboratory environment with various devices. As an example, the Japanese patent application no. JP2009229213 can be examined.
  • This invention includes the development of a urine sampling system that allows taking the urine sample without the intervention of the personnel or the patient for performing the visual analysis of the urine.
  • a urine sampling system that allows taking the urine sample without the intervention of the personnel or the patient for performing the visual analysis of the urine.
  • SUBSTITUTE SHEETS (RULE 26) for a different disease diagnosis.
  • the main subjects of this invention are the camera which can determine these biomarkers and the system that passes the urine through the camera.
  • Figure 1 The front view of the urinal embodiment of the urine sample color analysis system of the invention.
  • Figure 2 The rear view of the urinal embodiment of the urine sample color analysis system of the invention.
  • Figure 3 The perspective view of internal parts of the urine sample color analysis system of the invention that can be used in urinals or toilets.
  • Figure 4 The perspective view of the imaging unit of the urine sample color analysis system of the invention.
  • Figure 5 The exploded perspective view of the imaging unit of the urine sample color analysis system of the invention.
  • Figure 6 The cross-sectional view of the imaging unit of the urine sample color analysis system of the invention.
  • FIG. 7 The side view of the urine sample color analysis system of the invention which shows the sectional area of the imaging unit.
  • the parts in the drawings are enumerated and equivalents of numbers are given below.
  • the urine sample color analysis system (1) of present invention essentially comprises a monitoring line (6) that allows the urine sample conveyed to a monitoring line (6) to be passed through an imaging unit (7) with a camera (13).
  • the imaging unit (7) is an enclosed box so that it does not receive light from outside.
  • the urine sample conveyed to the monitoring line (6) located inside this box is monitored with the camera (13).
  • urine pumping is performed by the pump (5).
  • the urine sample is drawn from the collection container (2) where the urine is collected.
  • the collection container (2) allows that the air bubbles inside rise to the surface and the pump (5) only draws the urine by way of keeping the urine for a while.
  • the whole system operates according to a certain automation scenario to allow that the urine sample can be monitored with the camera (13) without operator and/or user touching it.
  • This scenario begins when the person who will undergo the urine measurement/imaging notifies the urine sample color analysis system (1) that they will urinate. For initialization, it is sufficient for the user to show a QR code, a bar code image, to the reader or to approach to the system and show his/her hand to the reader.
  • the urine will be collected in the sample collection container (2) with the user urinating in a urinal or toilet type apparatus.
  • the urine amount collected in the collection container (2) is instantly followed by a load cell (3).
  • the load cell (3) By means of the load cell (3), not only the start and end time of the urination process will be tracked, but also the amount of the urine collected can be acquired before the urine is sent to the imaging unit (7).
  • the load cell (7) can determine if the amount of the urine is below the lower limit value required for the imaging. In this case, the user will be notified that it is not possible to carry out the imaging process before the measurement starts.
  • the pump (5) will vacuum the urine in the collection container (2) through the urine suction line (6) and pump it to the monitoring line (6) according to the scenario.
  • the monitoring line (6) is a space between the upper body (8) and the lower body (9), and the flow line (10) passes through this space.
  • the urine reaches the monitoring line (6) immediately after the pump (5) operates.
  • the control card (11) will allow to record the photographs of the urine color with the operation of the pump (5) and operation of the camera (13) at the same time.
  • images taken by the camera (13) should not be affected by ambient light and each image should be recorded under the same conditions.
  • the monitoring line (6) will be illuminated before each recording by the lightning (14) inside the imaging unit (7).
  • the components of this lightning (7) system can not only provide lightning in different wavelengths (400nm-700nm) to create white light, but also provide lightning in ultraviolet (100nm-400nm) or infrared (700nm- lmm) wavelengths to identify specific biomarkers in the urine.
  • Images obtained from the monitoring line (6) by means of the camera (13) using the lightning (14) at different wavelengths are recorded by the control card (11). These images will be recorded regardless of whether the camera (13) records at visible wavelength or spectrometrically. From the images obtained, it can be determined whether the owner of the urine has one of the disease biomarkers, and what the content is from the liquid and solid food residues constituting the urine composition.
  • the urine directed directly by gravity from the urine collection bowl of the urinal or toilet can be passed through the monitoring line (6).
  • data based on the urine color can be processed without the collection container (2), the load cell (3), and the pump (5) by means of detecting the image with the most intense urine through the software from a series of photographs taken with the camera (13).
  • the urine sample color analysis system (1) may smell in a certain period of time due to residues as well as causing deterioration in image definition due to contamination of interior of the flow line (6). For this purpose, it is important to clean all components after each use. The cleaning process will be carried out by the user starting from the urine discharge stage until the end with clean water, soapy water, chemical-added water or a different fluid. At the same time, all of the collection container (2), the pump (5) and the monitoring line (6) will be cleaned.
  • the system only has a water connection, it is sufficient for the system to warn personnel to pour the additive fluids such as alcohol, soap, bleach directly into the bowl of the urinal or toilet.
  • the urine sample color analysis system (1) which cleans itself with high-pressure mains water after each use, can add the additive to this water itself.
  • a certain amount of cleaning chemical will be autonomously provided to the system continuously via a venturi connection to be added behind an inlet valve that opens and closes the mains water.
  • the open time of the mains water valve will be monitored by the urine sample color analysis system (1), and will warn the operator to carry out refilling when it is almost empty.
  • the urine sample color analysis system (1) will be able to perform the urine temperature measurement as well as the color analysis and biomarker control.
  • the urine coming directly from the bladder is at internal body temperature. Therefore, it can be immediately determined from the temperature of the urine whether the user is suffering from an inflammatory disease.
  • it is possible to access information about the color of the urine by using a color sensor instead of the camera (13).
  • a cost-efficient system can be achieved which responds fast by requiring less processor power.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Physiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Hydrology & Water Resources (AREA)
  • Water Supply & Treatment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention se rapporte à un système d'échantillon d'urine qui permet à l'échantillon d'urine d'être pris pour être utilisé dans des tests de laboratoire à prendre sans interrompre la personne lorsqu'elle urine. L'invention recueillera l'urine du patient durant le test de mesure du débit d'urine et transfèrera une certaine quantité de l'urine au récipient de test. Ainsi, il sera possible d'utiliser l'échantillon dans des tests de laboratoire qui est obtenu durant le test du débit d'écoulement d'urine. Le système transfèrera automatiquement l'échantillon d'urine requis dans le cadre de l'échantillonnage vers le récipient d'échantillon, en effectuant les étapes durant et après le procédé de miction que le patient effectue normalement à partir de qui l'échantillon d'urine doit être pris. Ensuite, le système nettoiera le réservoir d'urine.
PCT/TR2021/050389 2020-04-27 2021-04-26 Système d'analyse de couleur d'un échantillon d'urine WO2021221588A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2020/06566 2020-04-27
TR202006566 2020-04-27

Publications (1)

Publication Number Publication Date
WO2021221588A1 true WO2021221588A1 (fr) 2021-11-04

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ID=78374185

Family Applications (1)

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PCT/TR2021/050389 WO2021221588A1 (fr) 2020-04-27 2021-04-26 Système d'analyse de couleur d'un échantillon d'urine

Country Status (1)

Country Link
WO (1) WO2021221588A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5625911A (en) * 1994-02-23 1997-05-06 Toto Ltd. Apparatus for sampling urine
US20180184906A1 (en) * 2015-08-03 2018-07-05 Thomas Prokopp Device and method for the mobile analysis of excrement in a toilet
CN109083241A (zh) * 2018-09-26 2018-12-25 陈宣亦 一种检测身体特征的家用马桶
US10383606B1 (en) * 2018-07-16 2019-08-20 Bloom Health, Inc. Toilet based urine analysis system
US20190369085A1 (en) * 2018-05-31 2019-12-05 Kohler Co. Health seat for toilets and bidets

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5625911A (en) * 1994-02-23 1997-05-06 Toto Ltd. Apparatus for sampling urine
US20180184906A1 (en) * 2015-08-03 2018-07-05 Thomas Prokopp Device and method for the mobile analysis of excrement in a toilet
US20190369085A1 (en) * 2018-05-31 2019-12-05 Kohler Co. Health seat for toilets and bidets
US10383606B1 (en) * 2018-07-16 2019-08-20 Bloom Health, Inc. Toilet based urine analysis system
CN109083241A (zh) * 2018-09-26 2018-12-25 陈宣亦 一种检测身体特征的家用马桶

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