WO2021182660A1 - Système et procédé de diagnostic objectif des huit constitutions - Google Patents

Système et procédé de diagnostic objectif des huit constitutions Download PDF

Info

Publication number
WO2021182660A1
WO2021182660A1 PCT/KR2020/003499 KR2020003499W WO2021182660A1 WO 2021182660 A1 WO2021182660 A1 WO 2021182660A1 KR 2020003499 W KR2020003499 W KR 2020003499W WO 2021182660 A1 WO2021182660 A1 WO 2021182660A1
Authority
WO
WIPO (PCT)
Prior art keywords
constitution
index
iris
correlation
objective
Prior art date
Application number
PCT/KR2020/003499
Other languages
English (en)
Korean (ko)
Inventor
최가혜
임영우
Original Assignee
주식회사 누베베
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 누베베 filed Critical 주식회사 누베베
Publication of WO2021182660A1 publication Critical patent/WO2021182660A1/fr

Links

Images

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00Machine learning
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment

Definitions

  • the present invention relates to an objective arm constitution diagnosis system and method, and more specifically, to a quantitative evaluation of iris indicators, heart rate variability and body composition analysis to evaluate autonomic nerve activity, It relates to an objective arm constitution diagnosis system and method that can objectively diagnose arm constitution through correlation.
  • Kwon Do-won of Korea classified humans into eight constitutions (Toeum, Soil, Mokeum, Mokyang, Masturbation, Suyang, Geumeum, Geumyang) according to the strength and weakness of the books in order to precisely classify acupuncture treatment through constitutional classification. It is also widely used in oriental medicine. Kwon Do-won's arm constitution is different from the Sasang constitution or there is a significant deviation.
  • the eight constitutions (8 constitutions) that are divided in this way have different physiology and pathological mechanisms.
  • jeok imbalance the congenital imbalance of the book function
  • hyperbalance the acquired pathology, that is, the state where the balance of the fossa imbalance is broken.
  • constitutional classification is primarily done through pulse pulse, but constitutional pulse assessment requires a long skillful process, and even an experienced oriental medical doctor's constitutional diagnosis is based on subjective evaluation of the pulse, so there is a problem with low objectivity. .
  • iris studies is a study that analyzes the innate characteristics and functional state of an individual through the analysis of the color or structural characteristics and changes of the iris, that is, the iris markers.
  • the iris marker does not change over time and reflects the genetic temperament, so there may be a relationship between the constitution and the iris.
  • the concept of balance and homeostasis of the autonomic nervous system may be related to constitution in that it is a change and regulation of human functions. This method is known to have relatively high reliability and reproducibility.
  • bioelectrical impedance analysis measures the resistance value (impedance) of the body by passing minute electric currents through the human body, and uses this to quantitatively measure the body water, minerals, body fat content, etc., which are components of the human body. Measuring and analyzing, the measurement method is simple and the measurement time is short, so it is widely used in clinical practice.
  • the present invention has been devised to solve these problems, and an object of the present invention is to use iris indicators that can be easily and simply quantitatively evaluated, heart rate variability and body composition analysis to evaluate autonomic nerve activity, iris indicators and biosignals according to arm constitution. It aims to provide an objective diagnosis system and method for the body constitution that can be objectively diagnosed through correlation with the body constitution and can be effectively used for treatment, food classification, and regimen according to each constitution.
  • An objective arm constitution diagnosis system includes: a user terminal of a user who requests a diagnosis of arm constitution and treatment, food classification, and regimen according to the diagnosis of the arm constitution; an arm constitution diagnosis server for objectively diagnosing a user's constitution according to a user's request of the user terminal and providing a customized prescription; And it is connected to the user terminal and the arm constitution diagnosis server through a network so that the arm constitution diagnosis server can objectively diagnose and provide customized prescription, and 8 constitutional pulse information, redness index, HRV information, body composition index information, and their correlations It is characterized in that it includes an objective data providing server that provides relationship information.
  • An objective method for diagnosing arm constitutions includes the steps of determining the validity of an 8 constitutional pulse for any one of the 8 constitutions transmitted through a pulse through an 8 constitutional pulse expert terminal;
  • the user's iris index received from the iris diagnosis expert terminal, the autonomic nerve activity of the autonomic nerve activity evaluation terminal, the user's body composition index received from the body composition index evaluation terminal, and the pulse received from the 8 constitutional pulse expert terminal It characterized in that it comprises the step of judging the validity of the results of the pulse by using the correlation of the redness index by constitution, autonomic nerve activity, body composition index, etc. by using the results.
  • the objective arm constitution diagnosis system and method uses iris indicators that can be easily and simply quantitatively evaluated, heart rate variability and body composition analysis to evaluate autonomic nerve activity, iris indicators and biosignals according to arm constitution. By diagnosing the body constitution objectively, it can be effectively used for treatment, food classification and regimen according to each constitution.
  • FIG. 1 is a schematic diagram of an objective arm constitution diagnosis system according to an embodiment of the present invention.
  • FIG. 2 is a block diagram illustrating the internal configuration of the objective arm constitution diagnosis server 100 of the objective arm constitution diagnosis system according to an embodiment of the present invention.
  • FIG. 3 is a block diagram illustrating the internal configuration of the objective data providing server 200 of the objective arm constitution diagnosis system according to an embodiment of the present invention.
  • FIG. 4 is a flowchart illustrating an objective arm constitution diagnosis method using an objective arm constitution diagnosis system according to an embodiment of the present invention.
  • FIG. 5 is a chart illustrating a method for examining the correlation between the iris index, body composition index, and HRV and the clinical characteristics of eight constitutions (Eight Constitution Medicine Type) in the objective arm constitution diagnosis method according to an embodiment of the present invention. .
  • FIG. 6 is a photograph showing an iris imaging method
  • FIG. 7 is a photograph showing the definition of ANWAR and PAR
  • FIG. 8 is a photograph showing markers of five iris constitutional analysis used to calculate or grade six iris parameters. am.
  • 9 to 12 are photographs showing NR in Geumyang constitution, TR in Geumeum constitution, lacunae in Mokyang constitution, and PD in soil constitution, respectively.
  • first, second, etc. are used to describe various elements, components, and/or sections, these elements, components, and/or sections are not limited by these terms. These terms are only used to distinguish one element, component, or sections from another. Accordingly, it goes without saying that the first element, the first element, or the first section mentioned below may be the second element, the second element, or the second section within the spirit of the present invention.
  • HRV heart rate variability for evaluating autonomic activity
  • BMI Body Mass Index
  • ANWR Autonomic Nerve Wreath Ratio
  • PAR pupil area ratio. (pupil area ratio)
  • ID is iris density
  • PD pigment dot
  • NR nerve ring
  • TR is toxic radii
  • TP Total Power
  • VLF Very Low Frequency
  • LF Low Frequency
  • HF High Frequency.
  • the arm constitution diagnosis server 100 objectively evaluates the user's constitution according to the user's request in the user terminal 10.
  • the 8 constitutional pulse information, Hongjae index, HRV information, body composition index information, and their correlation information collected from each objective data providing server 200 through the network 50 It is configured to generate objective arm constitution diagnosis information and provide it to the user terminal 10 through the network 50 .
  • the user terminal 10 may be a patient terminal that requires an objective arm constitution diagnosis, or may be an oriental medicine doctor terminal for accurately prescribing oriental medicine to the patient according to the objective arm constitution information.
  • the arm constitution diagnosis server 100 includes an information acquisition unit 110 that acquires iris index, body composition index, HRV, and pulse information of 8 constitutions from the user terminal 10 and the objective data providing server 200 .
  • the information generation unit 120 that determines the correlation between the information obtained through the information acquisition unit 110 and generates objective arm constitution diagnosis information with guaranteed objectivity, and the information generation unit 120
  • the objective information generated through ) is learned through the learning unit 150 to be described later, and the AI objective diagnosis unit 130 supporting the information generation unit 120 and the information generation unit 120 are generated through the A reclassification/correction unit 140 that reclassifies and corrects arm constitution information using the information provided by the AI objective diagnosis unit 130 for cases outside the statistical standard deviation range in the process of examining the objective validity of the information.
  • the information acquisition unit 110 the information generation unit 120 , the AI objective diagnosis unit 130 , and the database unit 170 for storing and registering information of the reclassification/correction unit 140 ) and a learning unit 150 for learning the information of the information generating unit 120 , the AI objective diagnosis unit 130 , and the reclassification/correction unit 140 .
  • the information generating unit 120 includes an 8 constitutional pulse validity review unit 121 that reviews the validity of the 8 constitutional pulse, an iris index/age correlation review unit 123 that reviews the correlation between the iris index and age, and the iris It may include an indicator/HRV correlation review unit 125 , a body composition index correlation review unit 127 for Hongjae index, and a correlation review unit 129 for each constitution.
  • the distribution by 8 constitutions is shown in the order of the frequency of soil, Mokyang, Geumeum, and Geumyang (similar to the distribution by 8 constitutions of subjects observed in the previous study of Jo and Kwon), with very few constitutions of Mokeum, Suyang, and Masturbation, and Toeum constitution. is not reported, the 8 constitutional pulse validity review unit 121 confirms the validity of the 8 constitutional pulse based on this statistical probability distribution standard.
  • the iris index / age correlation review unit 123 decreases PAR as the age of the entire subject increases, and PD increases. As age increases, PAR decreases, It can be judged that the validity is high when the PD increases.
  • the higher the ID the higher the LF/HF value, and the ID increases as the number of lacuna increases.
  • the Hongjae index body composition index correlation review unit 127 may determine that the greater the PAR, the greater the BMI, body weight, lean mass, and body fat mass.
  • the correlation review unit 129 for each constitution shows a positive correlation between NR and BMI in the Geumyang constitution, and a positive correlation between NR and skeletal muscle mass, body water, and weight in the Geumyang constitution, and ID and skeletal muscle mass in the Mokyang constitution. , a positive correlation with body water is shown, a negative correlation between PD and body fat percentage in soil constitution, and a positive correlation between PAR and lean body mass can be judged to be highly valid.
  • the correlation review unit 129 for each constitution shows a positive correlation between ID and LF/HF for Geumyang constitution, a positive correlation between TR and heart rate, and a negative correlation between PAR and LF/HF.
  • TR and LF/HF have a positive correlation
  • Mokyang constitution PAR, LF/HF and heart rate have a positive correlation
  • Geumyang constitution PAR and LF/HF have a negative correlation.
  • the AI objective diagnosis unit 130 learns the statistical probability information provided through the information generation unit 120 through the learning unit 150, but sets NR in the case of Geumyang and Geumeum constitution, and ID in the case of Mokyang constitution. In constitution, by judging PD as an index that can indicate the singularity of constitution, objectivity can be increased while reducing learning data.
  • the AI objective diagnosis unit 130 learns the statistical probability information provided through the information generation unit 120 through the learning unit 150, and 8 constitutional pulse information in case of deviation from the validity category, Using the Hongjae index, HRV information, body composition index information, and their correlation information, through the reclassification/correction unit 140, the reclassification operation and the correction operation are performed to determine Mokeum, Suyang, Masturbation, or exceptionally Toeum constitution The validity of the case can be increased.
  • the AI objective diagnosis unit 130 generally performs the iris index, body composition, and HRV analysis and the learning unit 150 for the case where the tendency of the results is different when the analysis is performed by dividing the constitution.
  • the information of the database unit 170 it is determined where to place the weights, so that the information generating unit 120 can provide more objective information through an objective diagnosis.
  • the AI objective diagnosis unit 130 shows that PAR and ANWR are important, and in the analysis of the iris index and HRV, there is an important correlation in LF/HF and HR
  • NR and TR are important in Geumyang and Geumeum in the analysis results by arm constitution, ID in Mokyang constitution, and PD in soil constitution, significant weighting factors are changed, and the reclassification/reporting
  • the government 140 may reclassify and correct it.
  • the AI objective diagnosis unit 130 allows the information generating unit 120 to learn the overall correlation analysis result and the significant index appearing for each constitution through the learning unit 150, so that the overall correlation analysis result and the significant index appearing for each constitution are significant.
  • the indicators are displayed differently, different iris indicators for each constitution may indicate a peculiarity of the constitution.
  • the AI objective diagnosis unit 130 causes the information generating unit 120 to change the autonomic nervous balance control differently because the autonomic nervous system responses are different when the two constitutions are at rest, even if different results are shown in some of the same indicators. Considering that it can be done, the diagnosis information of the arm constitution can be generated, and objectivity can be guaranteed based on big data.
  • the objective data providing server 200 shoots the iris, determines the parameters, generates an iris index by classifying each parameter, and the iris diagnosis expert terminal 210 that performs iris medical health diagnosis, and simply measures the heart rate variability.
  • the iris diagnosis expert terminal 210, the autonomic nerve activity evaluation terminal 230, the body composition index evaluation terminal 250, the 8 constitutional pulse expert terminal 270 and the objective arm constitution diagnosis in the objective data providing server 200 It may include a terminal communication unit 280 for controlling communication between the servers 100 and a terminal control unit 290 for controlling each of them.
  • the iris diagnosis expert terminal 210 includes an iris photographing unit 211 for photographing the iris, and a parameter determination unit 213 for determining a parameter for extracting medical information from the iris photographed by the iris photographing unit 211 . ), and the parameter-specific grade determination unit 215 that determines the parameter-specific grade that can provide meaningful medical information about the parameter, and the parameter-specific grade determination unit 215 according to the grade determined by the iris medically meaningful It may include an ANWR/PAR calculation unit 217 that calculates the ANWR and PAR (which will be described in detail later with reference to FIGS. 6 to 8 ).
  • the autonomic activity evaluation terminal 230 includes an HRV measuring unit 231 for measuring HRV and a parameter calculating unit 233 for calculating four frequency domain parameters using the HRV measured by the HRV measuring unit 231 . ) may be included.
  • the body composition index evaluation terminal 250 may include a BMI measurement unit 251 and a body composition index calculator 253 that calculates body composition indices using the BMI measurement information.
  • FIG. 4 is a flowchart illustrating an objective arm constitution diagnosis method using an objective arm constitution diagnosis system according to an embodiment of the present invention.
  • the objective arm constitution diagnosis method examines the validity of any one of the 8 constitutions transmitted by pulse through the 8 constitution pulse expert terminal 270 Received from the unit 121, it is determined whether the validity of the 8 constitutional pulse is within a statistical distribution range (S10).
  • any one of the transmitted constitutions is one of the distribution of 8 constitutions with high domestic statistical probability, such as Soil, Mokyang, Geumeum, and Geumyang constitutions
  • it is determined that the validity of the true pulse is high (S11)
  • S80 the objectivity is increased through the reclassification operation and the correction operation (S80), and it can be determined as an exceptional voice, yang, masturbation, or toeum constitution. have.
  • the iris index/age correlation review unit 123 uses the user age received through the user terminal 10 and the iris index characteristic received from the iris diagnosis expert terminal 210 to determine the age between the iris index and the age. A correlation may be determined (S20).
  • the iris index/age correlation review unit 123 can determine that there is validity when the PAR decreases and the PD increases as the age of the entire subject increases. and (S21), otherwise (S23), it is stored in the database unit 170 and the contents of the database unit 170 are learned through the AI objective diagnosis unit 130 and the learning unit 150, and the validity category in case of departure from It can be reclassified/corrected in consideration of the constitution through the reclassification/correction unit 140 (S70).
  • the redness index body composition index correlation review unit 127 uses the iris index characteristics received from the iris diagnosis expert terminal 210 and the body composition index received from the body composition index evaluation terminal 250 to determine the redness index and body composition. It may be determined whether the correlations of the indicators match (S30).
  • the Hongjae index body composition index correlation review unit 127 determines that the greater the PAR, the greater the BMI, body weight, lean mass, and body fat mass, and the larger the ANWR, the higher the validity is when the lean mass, body fat mass, and body fat percentage decrease (S31). , otherwise (S33), the database unit 170 stores it and learns the contents of the database unit 170 through the AI objective diagnosis unit 130 and the learning unit 150, and deviates from the validity category. about It can be reclassified/corrected in consideration of the constitution through the reclassification/correction unit 140 (S70).
  • the iris index/HRV correlation review unit 125 measures the iris index characteristics received from the iris diagnosis expert terminal 210 and the heart rate variability measurement unit 231 of the autonomic nerve activity evaluation terminal 230 . It can be determined whether the correlation between the iris index and the autonomic nerve activity is consistent with the autonomic nerve activity such as HRV calculated using the obtained heart rate variability (S40).
  • the higher the ID the higher the LF/HF value, and the ID increases as the number of lacuna increases.
  • the constitutional correlation review unit 129 includes the user's iris index received from the iris diagnosis expert terminal 210 , the autonomic nerve activity of the autonomic nerve activity evaluation terminal 230 , and the body composition index evaluation terminal 250 . ) and the user's body composition index received from the 8 constitutional pulse expert terminal 270, the correlation between the redness index for each constitution, autonomic nerve activity, body composition index, etc. can be reviewed (S50).
  • the correlation review unit 129 for each constitution shows a positive correlation between NR and BMI in the Geumyang constitution, and a positive correlation between NR and skeletal muscle mass, body water, and weight in the Geumyang constitution, and ID and skeletal muscle mass in the Mokyang constitution. , a positive correlation with body water is shown, a negative correlation between PD and body fat percentage in soil constitution, and a positive correlation between PAR and lean body mass can be judged to be highly valid (S51), and the constitution
  • the star correlation review unit 129 stores in the database unit 170 for the other case (S53) and learns the contents of the database unit 170 through the AI objective diagnosis unit 130 and the learning unit 150. Therefore, in case of deviation from the validity category, It can be reclassified/corrected in consideration of the constitution through the reclassification/correction unit 140 (S70).
  • the learning unit 150 learns the information stored in the database unit 170 with respect to the reclassified/corrected information in consideration of the constitution through the reclassification/correction unit 140 as described above, and the AI objective diagnosis unit (130) judges NR in the case of Geumyang and Geumeum constitution, ID in Mokyang constitution, and PD in soil constitution as an index that can indicate the singularity of constitution, reducing learning data and increasing objectivity.
  • the AI objective diagnosis unit 130 learns the statistical probability information provided through the information generation unit 120 through the learning unit 150, and 8 constitutional pulse information in case of deviation from the validity category, Using the Hongjae index, HRV information, body composition index information, and their correlation information, through the reclassification/correction unit 140, the reclassification operation and the correction operation are performed to determine Mokeum, Suyang, Masturbation, or exceptionally Toeum constitution The validity of the case can be increased.
  • the AI objective diagnosis unit 130 generally performs the iris index, body composition, and HRV analysis and the learning unit 150 for the case where the tendency of the results is different when the analysis is performed by dividing the constitution.
  • the information of the database unit 170 it is determined where to place the weights, so that the information generating unit 120 can provide more objective information through an objective diagnosis.
  • the AI objective diagnosis unit 130 shows that PAR and ANWR are important, and in the analysis of the iris index and HRV, there is an important correlation in LF/HF and HR
  • NR and TR are important in Geumyang and Geumeum in the analysis results by arm constitution, ID in Mokyang constitution, and PD in soil constitution, significant weighting factors are changed, and the reclassification/reporting
  • the government 140 may reclassify and correct it.
  • the AI objective diagnosis unit 130 allows the information generating unit 120 to learn the overall correlation analysis result and the significant index appearing for each constitution through the learning unit 150, so that the overall correlation analysis result and the significant index appearing for each constitution are significant.
  • the indicators are displayed differently, different iris indicators for each constitution may indicate a peculiarity of the constitution.
  • the AI objective diagnosis unit 130 causes the information generating unit 120 to change the autonomic nervous balance control differently because the autonomic nervous system responses are different when the two constitutions are at rest, even if different results are shown in some of the same indicators. Considering that it can be done, the diagnosis information of the arm constitution can be generated, and objectivity can be guaranteed based on big data.
  • the correlation between the iris index, body composition index, and HRV and the clinical characteristics of 8 constitutions is investigated.
  • the correlation between the iris index, body composition index, and HRV and the clinical characteristics of 8 constitutions is investigated.
  • FIG. 5 is a chart illustrating a method for examining the correlation between the iris index, body composition index, and HRV and the clinical characteristics of eight constitutions (Eight Constitution Medicine Type) in the objective arm constitution diagnosis method according to an embodiment of the present invention. .
  • the method of examining the correlation between the iris index, body composition index, and HRV and the clinical characteristics of 8 constitutions (Eight Constitution Medicine Type) in the objective arm constitution diagnosis method according to an embodiment of the present invention is February 20, 2018 Adult men and women who visited three oriental clinics in Seoul for 4 months from June 30, 2018 were recruited and surveyed for a total of 244 (40 men, 204 women, average 37.54 years ⁇ 8.50).
  • the clinical study subjects wore comfortable clothes and rested in a quiet room.
  • the iris imaging was performed after sitting toward the examiner at a predetermined position in front of the iris imaging machine.
  • 6 is a photograph showing an iris photographing method.
  • the iris camera is Dr. Camscope Pro LED (Sometech, Seoul, Korea) was used, and the length of the eyepiece was fixed at 65mm during iris photography to maintain a constant distance between the shooting lens (25x magnifying glass) and the iris. At this time, constant illumination was maintained by irradiating the iris with a continuous light source of 2000 lux (led lamp) while blocking external light. Since the large light reflection occurs for 0.2-0.5 seconds after light source stimulation, iris photography was taken 1 second after irradiating the continuous light source in order to minimize the large light reflection.
  • the captured images were saved in a certain size and format (960*720pixel, JPEG), and were analyzed using the measure tool of the Adobe photoshop program based on the six iris indices developed in previous studies.
  • the six iris indices are autonomic nerve wreath ratio (ANWR), pupil area ratio (PAR), iris density (ID), pigment dot (PD), and nerve ring (NR). ; consists of nerve ring, pain congestive gland (TR; toxic radii),
  • FIG. 7 is a photograph showing the definitions of ANWAR and PAR.
  • ANWAR means autonomic nerve wreath ratio
  • PAR means pupil area ratio
  • A represents the length of the Autonomic Nerve Wreath (ANW)
  • B means the length of the pupil including the length of the autonomic nerve ring
  • C includes the iris and pupil. It means the total length of the eye
  • D means the length of the pupil.
  • ANWAR is defined as A/B and PAR is defined as D/C.
  • Figure 8 shows the markers of the five iris constitutions used to calculate or grade the six iris parameters.
  • A indicates a lacuna or defect
  • B is a pigment spot (PD)
  • C is a nerve ring (NR)
  • D is an autonomic nerve area ratio (ANW)
  • E is a painful stasis line (TR).
  • iris density, pigment spots, nerve rings, and painful stasis were determined as four parameters, and significant grades were divided according to constitution for each parameter and shown in Table 1.
  • [Table 1] shows the classification of scales for iris density, pigment spots, neural rings, and toxic radii.
  • HRV was measured using a pulse wave tester (uBio Maccpa; UBIO Health Care, Suwon, Korea), and mean heart rate (HR) values were used through time domain analysis.
  • TP Total Power
  • VLF very low frequency
  • LF low frequency
  • HF high frequency
  • body mass index BMI
  • percent body fat percent body fat
  • total body water percent body fat
  • skeletal muscle mass percent body fat
  • fat free mass percent body fat
  • WHR waist-hip ratio
  • [Table 5] shows the human correlation between iris index, body mass index, and heart rate variability.
  • LF/HF is an index indicating the ratio of sympathetic and parasympathetic nerves, and increased LF/HF means dominance of the sympathetic nervous system.
  • NR and BMI were positively correlated, and in Geumyang constitution, NR and skeletal muscle mass, body water, and weight showed a positive correlation.
  • TR and heart rate showed a positive correlation. It is recognized that TR is caused by excessive contraction, relaxation, or prolonged fiber tension in the superficial iris fibers 11 . Therefore, an increase in TR can be inferred by hyperactivity of the sympathetic nervous system. PAR and LF/HF showed a negative correlation. In the Geum-eum constitution, a positive correlation between TR and LF/HF was found, suggesting a correlation between the increase of TR and the sympathetic nervous system as in the Geum-yang constitution. PAR, LF/HF, and heart rate showed a positive correlation in the shepherd's constitution. This is the opposite result of the negative correlation between PAR and LF/HF in Geumyang constitution. In soil constitution, a positive correlation was found between ID and LF/HF. This was the same as the result in Geumyang constitution.
  • [Table 14] shows the correlation between the Hongjae index, HRV, and BMI according to the 8 constitutions when analysis was performed by dividing the constitution.
  • 9 to 12 are photographs showing NR in Geumyang constitution, TR in Geumeum constitution, lacuna in Mokyang constitution, and PD in soil constitution, respectively.
  • the objective arm constitution diagnosis system and method uses iris indicators that can be easily and simply quantitatively evaluated, heart rate variability and body composition analysis to evaluate autonomic nerve activity, iris indicators and biosignals according to arm constitution. By diagnosing the body constitution objectively, it can be effectively used for treatment, food classification and regimen according to each constitution.

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Primary Health Care (AREA)
  • General Health & Medical Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Databases & Information Systems (AREA)
  • Pathology (AREA)
  • Software Systems (AREA)
  • Theoretical Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Mathematical Physics (AREA)
  • Evolutionary Computation (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Medical Treatment And Welfare Office Work (AREA)

Abstract

La présente invention porte sur un système de diagnostic objectif des huit constitutions qui peut diagnostiquer objectivement les huit constitutions par corrélation entre un indice d'iris et un biosignal en fonction des huit constitutions au moyen de l'indice d'iris évaluable quantitativement, d'une variabilité de la fréquence cardiaque qui évalue l'activité nerveuse autonome, et de l'analyse de composition du corps. Le système comprend : un terminal d'utilisateur auquel un utilisateur demande un diagnostic des huit constitutions, et un traitement, un classement alimentaire, et un régime en fonction du diagnostic ; un serveur de diagnostic des huit constitutions destiné à diagnostiquer objectivement une constitution de l'utilisateur en fonction de la demande de l'utilisateur par le biais du terminal d'utilisateur et à transmettre une ordonnance personnalisée ; et un serveur de transmission de données objectives connecté au terminal d'utilisateur et au serveur de diagnostic des huit constitutions par le biais d'un réseau et transmettant des informations de pouls des huit constitutions, un indice d'iris, des informations de VFC, des informations d'indice de composition du corps, et leurs informations de corrélation, afin de permettre le diagnostic objectif et l'ordonnance personnalisée par le serveur de diagnostic des huit constitutions.
PCT/KR2020/003499 2020-03-12 2020-03-13 Système et procédé de diagnostic objectif des huit constitutions WO2021182660A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020200030867A KR102198816B1 (ko) 2020-03-12 2020-03-12 객관적인 팔체질 진단시스템 및 객관적 팔체질 모니터링 방법
KR10-2020-0030867 2020-03-12

Publications (1)

Publication Number Publication Date
WO2021182660A1 true WO2021182660A1 (fr) 2021-09-16

Family

ID=74140951

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2020/003499 WO2021182660A1 (fr) 2020-03-12 2020-03-13 Système et procédé de diagnostic objectif des huit constitutions

Country Status (2)

Country Link
KR (1) KR102198816B1 (fr)
WO (1) WO2021182660A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102444793B1 (ko) * 2021-07-02 2022-09-20 박성일 홍채 분석을 통한 건강 솔루션 제공 장치, 시스템 및 방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000063828A (ko) * 2000-08-05 2000-11-06 이명수 전자식 체질진단시스템 및 신호처리 방법
KR20020023608A (ko) * 2000-09-23 2002-03-29 이종균 홍채무늬에 따른 인성 및 체질 분석 시스템 및 방법과프로그램 기록매체
KR100902575B1 (ko) * 2007-12-10 2009-06-11 박성일 홍채를 촬영한 이미지를 4타입으로 분류하는 홍채 이미지 분석방법
KR20130026845A (ko) * 2011-09-06 2013-03-14 한국 한의학 연구원 설문 정보를 이용한 건강 상태 판단 장치 및 방법, 건강 분류 함수 생성 장치 및 그 방법
KR20180101092A (ko) * 2017-03-03 2018-09-12 주식회사 누베베 홍채 패턴을 분석하여 비만 치료의 예후를 예측하는 비만 관리 시스템 및 방법

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000063828A (ko) * 2000-08-05 2000-11-06 이명수 전자식 체질진단시스템 및 신호처리 방법
KR20020023608A (ko) * 2000-09-23 2002-03-29 이종균 홍채무늬에 따른 인성 및 체질 분석 시스템 및 방법과프로그램 기록매체
KR100902575B1 (ko) * 2007-12-10 2009-06-11 박성일 홍채를 촬영한 이미지를 4타입으로 분류하는 홍채 이미지 분석방법
KR20130026845A (ko) * 2011-09-06 2013-03-14 한국 한의학 연구원 설문 정보를 이용한 건강 상태 판단 장치 및 방법, 건강 분류 함수 생성 장치 및 그 방법
KR20180101092A (ko) * 2017-03-03 2018-09-12 주식회사 누베베 홍채 패턴을 분석하여 비만 치료의 예후를 예측하는 비만 관리 시스템 및 방법

Also Published As

Publication number Publication date
KR102198816B1 (ko) 2021-01-05

Similar Documents

Publication Publication Date Title
Swanson et al. Semiautomated computer analysis of vessel growth in preterm infants without and with ROP
JP4817582B2 (ja) 視覚機能の対物電気生理学的評価方法および装置
Smith et al. A simple diagnostic test for pupillary abnormality in diabetic autonomic neuropathy
US20020024633A1 (en) Pupil evaluation system
WO2013094995A1 (fr) Système d'autodiagnostic du champ visuel faisant appel à un ordinateur personnel et méthode d'autodiagnostic du champ visuel
WO2017160015A1 (fr) Système de contrôle d'apnée du sommeil
Acton et al. Comparing the Nidek MP-1 and Humphrey field analyzer in normal subjects
Mavilio et al. Can variability of pattern ERG signal help to detect retinal ganglion cells dysfunction in glaucomatous eyes?
Schallenberg et al. Comparison of the Colvard, Procyon, and Neuroptics pupillometers for measuring pupil diameter under low ambient illumination
Lowe et al. The arclight ophthalmoscope: a reliable low-cost alternative to the standard direct ophthalmoscope
Lei et al. Test–retest reliability of hemifield, central-field, and full-field chromatic pupillometry for assessing the function of melanopsin-containing retinal ganglion cells
WO2021182660A1 (fr) Système et procédé de diagnostic objectif des huit constitutions
Hain et al. Vestibular testing
WO2019014955A1 (fr) Terminal mobile pour la détection de la glycémie
Misra et al. Corneal confocal microscopy in type 1 diabetes mellitus: a six-year longitudinal study
CASCIO A study of vision in cerebral palsy
Bayram et al. Clinical practice of horizontal video head impulse test in healthy children
Loyd et al. Characterizing gaze and postural stability deficits in people with multiple sclerosis
Caporali et al. Intrarater and interrater agreement and reliability of vestibular evoked myogenic potential triggered by galvanic vestibular stimulation (galvanic-VEMP) for HTLV-1 associated myelopathy testing
EP1865838B1 (fr) Appareil de depistage du glaucome
Skaat et al. Pupillometer-based objective chromatic perimetry in normal eyes and patients with retinal photoreceptor dystrophies
WO2021085772A1 (fr) Procédé et appareil d'évaluation d'un déclin cognitif dégénératif sur la base d'un mouvement oculaire
Kunumpol et al. GlauCUTU: virtual reality visual field test
Zhao et al. Quantitative analysis of related parameters of retinal nerve fiber layer and ganglion cell complex thickness in patients with different degrees of Parkinson's disease
JP2001309890A (ja) 脳機能検査方法及びその装置

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20924182

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 20924182

Country of ref document: EP

Kind code of ref document: A1