WO2021181890A1 - Dispositif, système et procédé de mesure de signal électrique - Google Patents

Dispositif, système et procédé de mesure de signal électrique Download PDF

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Publication number
WO2021181890A1
WO2021181890A1 PCT/JP2021/001586 JP2021001586W WO2021181890A1 WO 2021181890 A1 WO2021181890 A1 WO 2021181890A1 JP 2021001586 W JP2021001586 W JP 2021001586W WO 2021181890 A1 WO2021181890 A1 WO 2021181890A1
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WIPO (PCT)
Prior art keywords
electric signal
electrode
living body
measuring device
signal measuring
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PCT/JP2021/001586
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English (en)
Japanese (ja)
Inventor
真央 勝原
一成 吉藤
僚 佐々木
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ソニーグループ株式会社
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Priority to JP2022505808A priority Critical patent/JPWO2021181890A1/ja
Publication of WO2021181890A1 publication Critical patent/WO2021181890A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]

Definitions

  • This technology relates to an electric signal measuring device, an electric signal measuring system, and an electric signal measuring method.
  • Non-Patent Document 1 and Patent Document 1 the component corresponding to the common mode noise is inverted and amplified and returned to the living body via the electrode to reduce the common mode noise. Techniques for reduction are described.
  • wet electrodes called wet electrodes are generally used for research and medical applications.
  • the wet electrode is an electrode that reduces the contact impedance with a living body by using gel, physiological saline, or the like.
  • the dry electrode can be easily attached, but there is a problem that the reduction of common mode noise becomes insufficient when the contact state between the electrode and the living body changes due to, for example, body movement or improper attachment.
  • the present technology provides an electric signal measuring device, an electric signal measuring system, and an electric signal measuring method for measuring biological information with high accuracy even if the contact state between the electrode and the living body changes due to body movement or the like. Is the main purpose.
  • an electrode for detecting an electric signal from a living body and a voltage used for common mode feedback based on contact state information between the living body and the electrode obtained from the electric signal.
  • an electric signal measuring device including at least a determination unit for determining the above voltage and a feedback unit for applying the voltage to the living body.
  • the electrode may be a dry electrode.
  • the contact state information may include contact impedance.
  • the contact state information may include the amplitude of the electrical signal.
  • the determination unit may determine the voltage by comparing the contact state information with a predetermined threshold value.
  • the determination unit may analyze the tendency of the contact state information to determine the voltage.
  • the electrode may have a switch.
  • the electrode may have a variable resistor.
  • the present technology includes an electrode that detects an electric signal from a living body and a determination unit that determines a voltage used for common mode feedback based on contact state information between the living body and the electrode obtained from the electric signal.
  • an electric signal measurement system including at least a feedback unit that applies the voltage to the living body.
  • the electrode detects an electric signal from a living body, and the voltage used for common mode feedback is determined based on the contact state information between the living body and the electrode obtained from the electric signal. And the electrode applies the voltage to the living body, and at least the electric signal measurement method is provided.
  • the present technology will be described in the following order. 1.
  • First Embodiment of the present technology (Example 1 of an electric signal measuring device) (1) Outline of this embodiment (2) Judgment unit (3) Verification 2.
  • a second embodiment of the present technology (Example 2 of an electric signal measuring device) 3.
  • Third Embodiment of the present technology (Example 3 of an electric signal measuring device) 4.
  • Fourth Embodiment of the present technology (Example 4 of an electric signal measuring device) 5.
  • Fifth Embodiment of the present technology Example 5 of an electric signal measuring device
  • a sixth embodiment of the present technology (Example 6 of an electric signal measuring device) 7. Seventh Embodiment of this technology (electric signal measurement system) 8.
  • Eighth Embodiment of the present technology (electric signal measurement method)
  • FIG. 1 is a circuit diagram showing a circuit configuration of the electric signal measuring device according to the first embodiment.
  • the electric signal measuring device 1000 includes at least a plurality of electrodes 100 to 300, a determination unit 500, and a feedback unit 400.
  • Each of the plurality of electrodes 100 to 300 is arranged at a position in contact with the skin surface of the living body S or at a position close to the skin surface of the living body S.
  • Each of the plurality of electrodes 100 to 300 detects an electric signal from the living body S.
  • an electroencephalogram (EEG) signal an electrocardiogram (ECG) signal, a magnetocardiogram (MCG) signal, a magnetoencephalogram (MEG) signal, a surface electromyogram (EMG) signal, an electrooculogram (EOG) signal, And there are skin potential (EDA) signals and the like.
  • the plurality of electrodes 100 to 300 will be described in more detail.
  • the plurality of electrodes 100 to 300 may be composed of a first detection electrode 100, a second detection electrode 200, and a third detection electrode 300.
  • the number of the plurality of electrodes 100 to 300 is not limited to three.
  • each of the first detection electrode 100 and the second detection electrode 200 detects an electric signal from the living body S.
  • the third detection electrode 300 detects an electric signal that serves as a reference for the electric potential from the living body S.
  • Each of the plurality of electrodes 100 to 300 may be a dry electrode.
  • Each of the plurality of electrodes 100 to 300 is a dry electrode, and even if the contact state between the electrodes and the living body changes due to body movement or the like, the electric signal measuring device 1000 measures the electric signal from the living body S with high accuracy. can.
  • the feedback unit 400 applies a voltage to the living body S. More specifically, the feedback unit 400 reduces the common mode noise by inverting and amplifying the component corresponding to the common mode noise and returning it to the living body (common feedback).
  • the first detection electrode 100 is composed of a first passive electrode 110 and a first active electrode 120.
  • the first active electrode 120 has, for example, a first switch 121, a first instrumentation amplifier 122, a first resistor 123, a first AD converter 124, a first switch switching unit 125, and the like. Can be done.
  • the second detection electrode 200 is composed of a second passive electrode 210 and a second active electrode 220, similarly to the first detection electrode 100.
  • the second active electrode 220 has, for example, a second switch 221, a second instrumentation amplifier 222, a second resistor 223, a second AD converter 224, a second switch switching unit 225, and the like. Can be done.
  • the third detection electrode 300 is composed of a third passive electrode 310 and a first operational amplifier 321.
  • the feedback unit 400 is composed of a fourth passive electrode 410 and a second operational amplifier 421.
  • the determination unit 500 is electrically connected to each of the plurality of electrodes 100 to 300 and the feedback unit 400.
  • the determination unit 500 obtains contact state information between the living body S and each of the plurality of electrodes 100 to 300 from the electric signals detected by each of the plurality of electrodes 100 to 300. Then, the determination unit 500 determines the voltage used for the common mode feedback based on the contact state information.
  • the determination unit 500 can be realized by using, for example, a microcomputer or the like.
  • the feedback unit 400 applies the voltage determined by the determination unit 500 to the living body S.
  • FIG. 2 is a flowchart showing the procedure of the determination unit according to the present embodiment.
  • the determination unit 500 obtains contact state information between the living body S and each of the plurality of electrodes 100 to 300 from the electric signals detected by each of the plurality of electrodes 100 to 300 (S1).
  • This contact state information may include, for example, the contact impedance or the amplitude of the electric signal.
  • the determination unit 500 determines the voltage used for common feedback based on the obtained contact state information (S2).
  • This determination method is not particularly limited, but to explain one example, the determination unit 500 may determine the voltage by comparing the contact state information with a predetermined threshold value. For example, when the contact impedance, which is an example of the contact state information, is equal to or higher than a predetermined threshold value (S2: Yes), the determination unit 500 disconnects the detection electrode that detects the electric signal including the contact state information from the circuit (S3). ..
  • the predetermined threshold value is not particularly limited.
  • the first detection electrode 100 detects an electric signal including contact state information equal to or higher than a predetermined threshold value. That is, it is assumed that the contact state between the first passive electrode 110 included in the first detection electrode 100 and the living body S is poor.
  • the determination unit 500 disconnects the first detection electrode 100 from the circuit. At this time, the determination unit 500 gives a disconnection instruction to the first switch switching unit 125. The first switch switching unit 125 changes the first switch 121 from the on state to the off state. As a result, the first detection electrode 100 is disconnected from the circuit.
  • the first switch 121 is realized by using, for example, a MOSFET.
  • the first switch switching unit 125 changes the first switch 121 from the on state to the off state by applying a predetermined voltage to the first switch 121.
  • the detection electrode may be separated by digital signal processing.
  • the determination unit 500 analyzes the tendency of the contact state information included in the electric signals detected by all the detection electrodes, and determines the voltage used for the common mode feedback. That is, when the determination is completed for all the detection electrodes (S4: Yes), the determination unit 500 determines the voltage used for the common mode feedback (S5).
  • the return unit 400 applies the voltage determined by the determination unit 500 to the living body S.
  • the common mode feedback is appropriately performed, so that the electric signal measuring device 1000 can measure the electric signal with high accuracy.
  • the timing at which each of the plurality of switches 121 and 221 is turned on and off may be each time an electric signal is detected or every time a predetermined number of times are specified.
  • an external reference signal obtained from an acceleration sensor or the like may be used as a trigger for determination by the determination unit 500.
  • the determination unit 500 configured by an event-driven algorithm may start the process when, for example, the contact state information changes to a predetermined threshold value or more.
  • the determination unit 500 may determine using the amplitude of the electric signal in addition to the above-mentioned contact impedance. For example, when this amplitude is equal to or greater than a predetermined threshold value, the determination unit 500 may disconnect the detection electrode that detects the electric signal including this amplitude from the circuit. By using the amplitude of the electric signal, the same effect can be obtained with a simpler circuit without using a current source.
  • the determination unit 500 may determine the voltage used for the common mode feedback by using a statistical algorithm.
  • the determination unit 500 may determine the voltage used for the common mode feedback, for example, based on the degree of variation from the average value in all the detection electrodes.
  • FIG. 3 is a circuit diagram showing a circuit configuration of a comparative example of an electric signal measuring device for explaining the effect of the present technology.
  • the electric signal measuring device 2000 includes at least a plurality of electrodes 100 to 300, a control unit 700, and a feedback unit 400.
  • the plurality of electrodes 100 to 300 for example, it is assumed that the contact state between the first passive electrode 110 of the first detection electrode 100 and the living body S is poor. In this case, the electric signal detected by the first detection electrode 100 contains a lot of noise.
  • the control unit 700 performs common feedback by applying a voltage to the living body S via the feedback unit 400 based on the electric signals obtained by each of the plurality of electrodes 100 to 300.
  • the electric signal from the living body S cannot be measured with high accuracy because the noise is superimposed and applied.
  • the electric signal measuring device 1000 has an effect that the electric signal from the living body S can be measured with high accuracy by removing the noise. Similar effects occur in other embodiments described below.
  • the measurement target is not limited to the living body.
  • a solid, a liquid, a gas, or the like having arbitrary circuit characteristics may be the object of measurement.
  • FIG. 4 is a circuit diagram of the electric signal measuring device used for this verification. Note that this circuit diagram is merely an example, and the circuit configuration of the electric signal measuring device 1000 is not limited to that shown in FIG.
  • this circuit includes a first channel Ch1 and a second channel Ch2.
  • Each of the first channel Ch1 and the second channel Ch2 has an input terminal (Sigma_IN, REF_IN) corresponding to an electrode. It is assumed that the contact impedance of the second channel Ch2 is higher than the contact impedance of the first channel Ch1.
  • FIG. 5 is an explanatory diagram of the verification result.
  • the first graph G1 shows the frequency and amplitude of the electric signal input to each of the plurality of input terminals (Sigma_IN, REF_IN) when the common mode feedback (DRL: Driven Right Leg) is not performed. Shown. As shown in the first graph G1, this electric signal contains common mode noise.
  • the second graph G2 shows the frequencies of the electric signals input to each of the plurality of input terminals (Sigma_IN, REF_IN) when the common mode feedback is performed based on the electric signals obtained from the first channel Ch1. And the amplitude are shown.
  • the electric signal obtained from the first channel Ch1 having a low contact impedance is used for the common mode feedback.
  • the electric signal obtained from the second channel Ch2 having a high contact impedance is not used for common feedback.
  • the common mode noise shown in the first graph G1 has been removed. Further, since the electric signal obtained from the second channel Ch2 having a high contact impedance is not used, the electric signal is measured with high accuracy.
  • the third graph G3 shows the frequencies of the electric signals input to each of the plurality of input terminals (Sigma_IN, REF_IN) when the common mode feedback is performed based on the electric signals obtained from the second channel Ch2. And the amplitude are shown.
  • the electrical signal obtained from the first channel Ch1 having a low contact impedance is not used for common mode feedback.
  • the electric signal obtained from the second channel Ch2 having a high contact impedance is not used for common feedback.
  • the amplitude is unstable and the electric signal can be measured with high accuracy. No. Moreover, the common mode noise is not removed.
  • the fourth graph G4 is input to each of a plurality of input terminals (Sig_IN, REF_IN) when common mode feedback is performed based on the electric signals obtained from the first channel Ch1 and the second channel Ch2. It shows the frequency and amplitude of the resulting electrical signal. This is the conventional common mode feedback.
  • FIG. 6 is an explanatory diagram of the verification result. In FIG. 6, the removal rate of common mode noise in each of the three patterns is shown.
  • the first pattern (left side) corresponds to the second graph G2 in FIG. 5, and is the common mode noise when the common mode feedback is performed based on the electric signal obtained from the first channel Ch1.
  • the removal rate of is shown. Of the three patterns, the removal rate of common mode noise is the highest. As a result, the electric signal is measured with high accuracy.
  • the second pattern corresponds to the third graph G3 in FIG. 5, and is the common mode noise when the common mode feedback is performed based on the electric signal obtained from the second channel Ch2.
  • the removal rate of is shown. Of the three patterns, the removal rate of common mode noise is the lowest.
  • the second channel Ch2 corresponds to an error electrode.
  • the third pattern (right side) corresponds to the fourth graph G4 in FIG. 5, and common mode feedback was performed based on the electric signals obtained from the first channel Ch1 and the second channel Ch2.
  • the removal rate of common mode noise at that time is shown. Insufficient removal of common mode noise.
  • this technology increases the removal rate of common mode noise.
  • the electric signal detected by the electrodes is measured with high accuracy.
  • FIG. 7 is a circuit diagram showing a circuit configuration of the electric signal measuring device according to the second embodiment.
  • the same components as those of the electric signal measuring device according to the first embodiment are designated by the same reference numerals, and detailed description thereof will be omitted.
  • each of the first active electrode 120 and the second active electrode 220 may have a variable resistor instead of the switch. That is, the first detection electrode 100 may have a first variable resistor 126. The second detection electrode 200 may have a second variable resistor 226.
  • the first switch switching unit 125 can change the resistance value of the first variable resistor 126. Specifically, the first switch switching unit 125 can change the resistance value of the first variable resistor 126, for example, by changing the voltage applied to the first variable resistor 126.
  • the second switch switching unit 225 can change the resistance value of the second variable resistor 226.
  • the determination unit 500 can adjust the amount of current flowing through each of the first variable resistor 126 and the second variable resistor 226. For example, when disconnecting the first detection electrode 100 from the circuit, the determination unit 500 instructs the first switch switching unit 125 to disconnect. The first switch switching unit 125 raises the resistance value of the first variable resistor 126. This reduces the amount of current flowing through the first variable resistor 126. As a result, the first detection electrode 100 is disconnected from the circuit.
  • the first switch switching unit 125 is provided independently of the first active electrode 120, but for example, the first active electrode 120 may have the first switch switching unit 125. The same applies to the second switch switching unit 225.
  • FIG. 8 is a circuit diagram showing a circuit configuration of the electric signal measuring device according to the third embodiment.
  • the same components as those of the electric signal measuring device according to the first and second embodiments are designated by the same reference numerals, and detailed description thereof will be omitted.
  • the determination unit 500 may have a function of switching each on / off state of the plurality of switches 121 and 221. That is, the electric signal measuring device 1000 according to the present embodiment does not have to independently include the switch switching unit.
  • the determination unit 500 changes the first switch 121 from the on state to the off state. As a result, the first detection electrode 100 is disconnected from the circuit.
  • FIG. 9 is a circuit diagram showing a circuit configuration of the electric signal measuring device according to the fourth embodiment.
  • the same components as those of the electric signal measuring device according to the first to third embodiments are designated by the same reference numerals, and detailed description thereof will be omitted.
  • the determination unit 500 may have a function of converting an analog signal into a digital signal. That is, as shown in FIG. 9, the electric signal measuring device 1000 according to the present embodiment does not have to be independently provided with the AD converter.
  • the determination unit 500 acquires the electric signals detected by each of the plurality of electrodes 100 to 300 as analog signals.
  • the determination unit 500 converts the electric signal of this analog signal into a digital signal, and determines the voltage used for the common mode feedback. Since it is not necessary to provide a plurality of AD converters, this technology can contribute to miniaturization of the device, for example.
  • FIG. 10 is a circuit diagram showing a circuit configuration of the electric signal measuring device according to the fifth embodiment.
  • the same components as those of the electric signal measuring devices according to the first to fourth embodiments are designated by the same reference numerals, and detailed description thereof will be omitted.
  • the second operational amplifier 421 included in the feedback unit 400 and each of the plurality of instrumentation amplifiers 122 and 222 are connected.
  • the feedback unit 400 can apply a voltage to the living body S and also apply a voltage to each of the plurality of instrumentation amplifiers 122 and 222.
  • the electric signal measuring device 1000 according to the present embodiment does not have to include a detection electrode for detecting an electric signal as a reference of the electric potential from the living body S. Thereby, this technology can contribute to the miniaturization of the device, for example.
  • FIG. 11 is a circuit diagram showing a circuit configuration of the electric signal measuring device according to the sixth embodiment.
  • the same components as those of the electric signal measuring devices according to the first to fifth embodiments are designated by the same reference numerals, and detailed description thereof will be omitted.
  • the electric signal measuring device 1000 does not have to be independently provided with an AD converter.
  • the determination unit 500 can convert an analog signal into a digital signal.
  • the electric signal measuring device 1000 may have a DA converter 600.
  • the DA converter 600 can convert a digital signal into an analog signal.
  • the determination unit 500 analyzes the tendency of the contact state information included in the electric signals obtained from each of the plurality of electrodes 100 to 300. Then, the determination unit 500 determines the voltage used for the common feedback. This voltage is applied to the living body S via the DA converter 600 and the feedback unit 400 without passing through each of the plurality of electrodes 100 to 300.
  • each of the first active electrode 120 and the second active electrode 220 does not have to have a switch or the like.
  • this technology can contribute to, for example, miniaturization of the device.
  • the electric signal measuring device 1000 has a function of the determination unit 500 to convert an analog signal into a digital signal, it may be provided with an AD converter independently.
  • FIG. 12 is a block diagram showing a configuration of an electric signal measurement system according to a seventh embodiment.
  • the electric signal measurement system according to the seventh embodiment may use the techniques according to the first to sixth embodiments. Therefore, the same components as those of the electric signal measuring devices according to the first to sixth embodiments are designated by the same reference numerals, and detailed description thereof will be omitted.
  • the electric signal measurement system 10000 includes at least a plurality of electrodes 100 to 300, a determination unit 500, and a feedback unit 400.
  • Each of the plurality of electrodes 100 to 300 is arranged at a position in contact with the skin surface of the living body S or at a position close to the skin surface of the living body S. Each of the plurality of electrodes 100 to 300 detects an electric signal from the living body S.
  • the feedback unit 400 applies a voltage to the living body S. More specifically, the feedback unit 400 reduces the common mode noise by inverting and amplifying the component corresponding to the common mode noise and returning it to the living body (common feedback).
  • the determination unit 500 is electrically connected to each of the plurality of electrodes 100 to 300 and the feedback unit 400.
  • the determination unit 500 obtains contact state information between the living body S and each of the plurality of electrodes 100 to 300 from the electric signals detected by each of the plurality of electrodes 100 to 300. Then, the determination unit 500 determines the voltage used for the common mode feedback based on the contact state information.
  • the determination unit 500 can be realized by using, for example, a microcomputer or the like.
  • the feedback unit 400 applies the voltage determined by the determination unit 500 to the living body S.
  • FIG. 13 is a flowchart showing the procedure of the electric signal measurement method according to the eighth embodiment.
  • the electric signal measurement method according to the present embodiment may use the techniques according to the first to seventh embodiments.
  • the electrode detects an electric signal from a living body (S100), and the contact state between the living body and the electrode obtained from the electric signal. Based on the information, it includes at least determining the voltage to be used for the common mode feedback (S200) and applying the voltage to the living body by the electrode (S300).
  • determining the voltage used for common mode feedback (S200) can be realized by using, for example, a microcomputer or the like.
  • the present technology can also have the following configurations.
  • the electrode is a dry electrode.
  • the contact state information includes the contact impedance.
  • the contact state information includes the amplitude of the electrical signal.
  • the electric signal measuring device according to any one of [1] to [3].
  • the determination unit determines the voltage by comparing the contact state information with a predetermined threshold value.
  • the electric signal measuring device according to any one of [1] to [4].
  • the determination unit analyzes the tendency of the contact state information and determines the voltage.
  • the electric signal measuring device according to any one of [1] to [5].
  • the electrode has a switch.
  • the electric signal measuring device according to any one of [1] to [6].
  • the electrode has a variable resistance, The electric signal measuring device according to any one of [1] to [7].
  • a feedback unit that applies the voltage to the living body, At least equipped with an electrical signal measurement system.
  • Electrodes detect electrical signals from the living body, Determining the voltage used for common mode feedback based on the contact state information between the living body and the electrode obtained from the electric signal.
  • An electrical signal measurement method that includes at least.
  • S Living body 1000: Electrical signal measuring device 100, 200, 300: Electrode 121, 221: Switch 126, 226: Variable resistance 400: Feedback unit 500: Judging unit 600: DA converter 10000: Electrical signal measuring system S100: Electrode is living body S200: Determining the voltage used for common mode feedback S300: Applying voltage to the living body

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

L'invention concerne un dispositif de mesure de signal électrique qui comprend au moins : une électrode afin de détecter un signal électrique provenant d'un corps vivant dans le but de mesurer des informations biologiques avec une précision élevée même lorsque l'état de contact entre l'électrode et le corps vivant change en raison du mouvement du corps, etc. ; une unité de détermination afin de déterminer une tension à utiliser dans une rétroaction en mode commun sur la base des informations sur l'état de contact entre le corps vivant et l'électrode, obtenues à partir du signal électrique ; une unité de rétroaction pour appliquer la tension au corps vivant.
PCT/JP2021/001586 2020-03-12 2021-01-19 Dispositif, système et procédé de mesure de signal électrique WO2021181890A1 (fr)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05168605A (ja) * 1991-12-25 1993-07-02 Nippon Koden Corp 生体信号増幅回路
JP2014124438A (ja) * 2012-12-27 2014-07-07 Denso Corp 心電計測システム
JP2016087061A (ja) * 2014-11-04 2016-05-23 東洋インキＳｃホールディングス株式会社 生体情報計測装置
JP2018047135A (ja) * 2016-09-23 2018-03-29 ホシデン株式会社 心電計測装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05168605A (ja) * 1991-12-25 1993-07-02 Nippon Koden Corp 生体信号増幅回路
JP2014124438A (ja) * 2012-12-27 2014-07-07 Denso Corp 心電計測システム
JP2016087061A (ja) * 2014-11-04 2016-05-23 東洋インキＳｃホールディングス株式会社 生体情報計測装置
JP2018047135A (ja) * 2016-09-23 2018-03-29 ホシデン株式会社 心電計測装置

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