WO2021143953A1 - 生物样品分析仪用的载物台、传送平台和生物样品分析仪 - Google Patents

生物样品分析仪用的载物台、传送平台和生物样品分析仪 Download PDF

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Publication number
WO2021143953A1
WO2021143953A1 PCT/CN2021/080953 CN2021080953W WO2021143953A1 WO 2021143953 A1 WO2021143953 A1 WO 2021143953A1 CN 2021080953 W CN2021080953 W CN 2021080953W WO 2021143953 A1 WO2021143953 A1 WO 2021143953A1
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WO
WIPO (PCT)
Prior art keywords
stage
board
plate
detection
carrier
Prior art date
Application number
PCT/CN2021/080953
Other languages
English (en)
French (fr)
Inventor
方炜
唐林勇
商涛
王中平
Original Assignee
利多(香港)有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202010048939.0A external-priority patent/CN113125690A/zh
Priority claimed from CN202021200373.0U external-priority patent/CN213482251U/zh
Application filed by 利多(香港)有限公司 filed Critical 利多(香港)有限公司
Priority to EP21740762.6A priority Critical patent/EP4174495A4/en
Priority to US17/758,807 priority patent/US20230044723A1/en
Publication of WO2021143953A1 publication Critical patent/WO2021143953A1/zh

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/069Absorbents; Gels to retain a fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099Characterised by type of test elements
    • G01N2035/00108Test strips, e.g. paper
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099Characterised by type of test elements
    • G01N2035/00148Test cards, e.g. Biomerieux or McDonnel multiwell test cards

Definitions

  • the invention belongs to the field of medical detection, and relates to a biological sample analyzer and its accessories, in particular a carrier, a transfer platform and a biological sample analyzer for the biological sample analyzer.
  • Urine analyzer as a kind of biological sample analyzer, is used to determine physiological indicators in urine.
  • a test strip or test card impregnated with urine this invention may also be referred to as "biological sample detection reagent” or simply “detection reagent" is placed on the stage and transported to the detection position. The test result is read by the instrument.
  • biological sample detection reagent or simply “detection reagent”
  • the first solution is to place the test strips or test cards on their corresponding brackets, and then place the brackets on a common carrier.
  • a common carrier For example, the urine analyzer of the US patent US7118713, when the operator replaces the test strip or test card with a test card or test strip, the carrier needs to be replaced at the same time. The operation steps are cumbersome and the carrier is equipped with a carrier. Placement will form a cleaning dead angle.
  • the second solution is to set a test card placement position on the carrier, and process the outer dimension of the test strip bracket so that it can also be placed in the test card placement position, such as the urine analyzer of US Pat. No. 6,239,445.
  • this solution lacks a test card tray, the tray still needs to be replaced repeatedly during use.
  • the third solution is to design the carrier on two sides, with one side for the test strip placement and the other for the test card placement.
  • a carrier usually requires a relatively large volume and occupies a relatively large space.
  • the operator needs to clean and dry the used side of the carrier first, and then connect the used side to the instrument, and the unused side is used to place the test card or test strip.
  • This type of stage can be placed on the front and back of the urine machine with different types of detection devices (test cards or test strips). When the type of detection device is changed, the download stage needs to be taken, cleaned and then placed in the instrument, and the operation steps are complicated.
  • the existing stage design has problems such as large instrument volume, multiple operation steps, difficult cleaning, and inconvenient use.
  • test card when the test card is placed on the stage, it is necessary to ensure that the test card can be accurately positioned in the testing instrument, so that the optical detection components of the instrument can be accurately aligned with the detection area of the test card to obtain accurate test results. If the test card is inaccurately positioned in the detection instrument, the active light source emitted by the optical detection component on the detection instrument cannot accurately illuminate the detection area, resulting in inaccurate detection results or errors.
  • some existing technologies can accurately locate, the locating process is cumbersome, time-consuming and labor-intensive, and work efficiency is low. Therefore, there is a need for a biological sample analyzer with a stage that is accurate in positioning and convenient and quick to operate.
  • the present invention provides a stage for a biological sample analyzer.
  • the stage serves as a transmission and detection device in the biological sample analyzer.
  • the stage can be realized without turning the stage over.
  • a test board and test strips for use with the stage are also provided. Simplifies the detection steps, improves detection efficiency, and reduces the risk of detection errors.
  • the present invention provides a stage for a biological sample analyzer, and a detection device limit structure is provided on one side of the stage that carries the detection device.
  • the side of the stage carrying the test strip is provided with a detection board limit structure, which can fix the detection board on the stage and ensure the accuracy of the placement direction of the detection board.
  • the detection board limiting structure is a boss that fits with the detection board, or a concave hole that fits the detection board, or a groove for accommodating the detection board, or a combination of a boss and a groove, or a concave hole Combination with grooves.
  • the boss can not only be matched with the detection board to limit the detection board on the stage, but also can limit the position of the test strip on the stage to ensure detection
  • the detection result area on the plate or test strip is exactly located in the light source detection area of the biological sample analyzer to ensure that the detection result can be accurately read by the biological sample analyzer.
  • the boss also has the function of supporting the test strip, especially the test strip wetted by the sample will be easily deformed due to the increase in weight, resulting in the deformation of the detection result area, and the detection result cannot be accurately collected. Therefore, it is particularly important that the test strip is supported.
  • the limit structure of the detection board is a concave hole
  • the concave hole is matched with the detection board to limit the detection board on the stage, and the test strip is also limited on the stage to make the test board and the test paper
  • the bars are all located in the detection area of a suitable light source.
  • the detection board limiting structure is a groove for accommodating the detection board, the detection board is restricted by the groove so that the detection board is located in the detection area of a suitable light source.
  • the height of the boss ensures that the detection height of the test strip on the boss is the same as the detection height of the test strip in the detection board on the boss.
  • the test results of the test board and the test strip can be located in the appropriate light source detection area of the biological sample analyzer, so as to ensure that the test results on the test board and test strip can be accurately read by the biological sample analyzer .
  • the protrusions or the recesses are arranged unevenly on the stage, which plays a role in preventing fools.
  • This uneven arrangement can be used to identify the direction in which the detection board is placed on the stage.
  • the uneven arrangement of the bosses is selected from the following methods or a combination of different methods, but is not limited to this list, for example, not arranged in the same straight line, the spacing between the bosses is not the same, and the boss to the groove end The distance between the protrusions is different, and the distance between the boss and the end of the groove is different from the distance between the bosses.
  • the number of bosses or recessed holes is one or more. More preferably, for example, three or more.
  • the boss or the concave hole is located in the groove.
  • the detection board can be contained and limited by the groove, and the position of the detection board can be further limited by the boss.
  • the three bosses located in the groove, and the three bosses are arranged unevenly. Specifically, the three bosses are arranged unevenly with different intervals.
  • a test strip positioning structure is also provided on the stage.
  • the positioning structure of the test strip is a card slot or a protruding nail at both ends of the stage, or a combination of a card slot and a protruding nail.
  • the card slots at both ends of the stage are a first card slot and a second card slot. Two protruding nails are respectively located in the first slot and the second slot
  • the center of the boss is located on the same straight line as the center of the first slot and the center of the second slot.
  • the first card slot and the second card slot are used for arranging and fixing the test strip, and they are used for positioning the test strip.
  • the center of the boss is on the same straight line as the center of the first slot and the center of the second slot, so that the boss becomes the bottom support of the test strip.
  • the first slot and the second slot are located at both ends of the groove that accommodates the detection board.
  • the three bosses located in the groove are distributed on a straight line, and the center lines of the bosses coincide with the center lines of the first slot and the second slot.
  • the depth of the groove for accommodating the test strip is greater than the depth of the first slot and the second slot on which the test strip is placed, so as to ensure the The test result is at the same height as the test result of the test strip.
  • both the first slot and the second slot are provided with bumps that support the test strip ,
  • the height of the bump is the same as the height of the bump.
  • the widths of the first slot and the second slot are the same as the width of the test strip, so as to better fix the test strip.
  • both ends of the first card slot are open; the width of the opening is the same as the width of the test strip; one end of the second card slot is open; the opening is provided with a symmetrical Protrusions; two side walls at the end of the second slot are provided with symmetrical protrusions; the distance between the protrusions at the opening of the second slot and the side wall protrusions is the same as the width of the test strip.
  • two side walls of the groove are provided with protruding strips protruding from the side walls; the protruding strips are adjacent to the ends of the groove; The spacing between the ribs of the side wall is equal to the width of the detection board.
  • the present invention also provides a detection board used for detection in a biological sample analyzer, and the detection board has a structure matched with the structure of the stage.
  • the detection board includes a bottom plate and a cover plate, and the back of the bottom plate is provided with a limit structure matching the limit structure of the detection plate on the stage.
  • the limiting structure on the back of the bottom plate is a concave hole or a protrusion.
  • concave holes or protrusions there are one or more concave holes or protrusions.
  • the concave hole corresponds to the convex platform on the stage, and the sizes, shapes, and positions of the two are in one-to-one correspondence.
  • the detection board is placed on the stage, the concave holes on the detection board are snapped on the convex platform of the stage one by one, so as to realize the fixation of the detection board and the determination of the direction of the detection board.
  • the limit structure on the back of the bottom plate is convex
  • the corresponding concave holes are provided on the stage, which can also realize the fixation of the detection board and the determination of the direction of the detection board.
  • the uneven arrangement of the concave holes or protrusions on the detection board also corresponds to the uneven arrangement of the protrusions or concave holes on the stage.
  • the concave holes or protrusions are located on the center line of the bottom plate.
  • a symmetrical recess is provided at the middle position of the two side walls of the bottom plate and the cover plate on the detection plate.
  • the present invention also provides a detection unit of a biological sample analyzer, which includes a movement mechanism and an optical detection system, as well as the carrier platform and the carrier transport platform described in the present invention.
  • the carrier platform is a rack plate, and the carrier table is detachably mounted on the rack plate.
  • the present invention also provides a biological sample analyzer, which includes a detection unit, which includes a movement mechanism and an optical detection system, and also includes the stage and the stage transport platform of the present invention.
  • the invention provides a transfer platform for a biological sample analyzer, which includes a movable carrying board and a carrying table.
  • the carrying table is placed on the carrying plate and can be separated from the carrying plate; the side of the carrying plate facing the carrying table The upper surface is the upper surface, and the opposite surface is the lower surface; the side of the stage facing the bearing plate is the lower surface, and the opposite side is the upper surface; the stage and the bearing plate are respectively equipped with magnetic blocks that attract magnetically.
  • the suction force of the magnetic block automatically positions the stage relative to the carrying plate.
  • the transfer platform used for the analyzer includes two pairs of magnetic blocks spaced at a proper distance from each other.
  • the two magnetic blocks on the stage have opposite polarities in the same direction, and the two magnetic blocks on the carrier plate are in the same direction.
  • the polarity is opposite, the magnetic block on the stage and the corresponding magnetic block on the carrying plate are arranged in an opposite sex attraction.
  • the surface of the carrier plate is provided with a recessed area in the area close to the magnetic block; when the orthographic projection of the magnetic block on the carrier plate on the carrier plate is located in the recessed area, the attractive force of the magnetic block causes the carrier to oppose the carrier plate Automatic positioning.
  • the surface of the carrier board is provided with a recessed area in the area directly above the magnetic block, and when the carrier is placed on the carrier board, the magnetic block on the carrier is located in the recessed area.
  • the contour of the recessed area on the carrying plate is rectangular, square, circular or elliptical, and its area is larger than the area of the bottom surface of the magnetic block mounted on the carrying plate.
  • the magnetic block on the carrying table is cylindrical. There is room for activity in the recessed area.
  • the magnetic block on the carrier at least partially protrudes from the lower surface of the carrier and enters the recessed area on the carrier plate.
  • the upper surface of the bearing plate and the lower surface of the stage are respectively provided with vertical walls that cooperate with each other.
  • the axis of the magnetic block on the bearing plate and the stage is offset from each other by 0.5-3.0 mm.
  • the magnetic block on the stage at least partially protrudes from the lower surface of the stage, the upper surface of the bearing plate is provided with counterbores, and the magnet blocks protruding from the stage fall into the counterbores on the bearing plate , And against the wall of the counterbore, so as to achieve automatic positioning.
  • a section of slope channel connected to the counterbore is provided on the upper surface of the bearing plate, and the slope channel gradually descends from a position farther from the counterbore to a position closer to the counterbore.
  • the uppermost opening of the counterbore is provided with a larger cone chamfering guide hole, the depth of the chamfer is 0.3-2.0 mm, and the angle between the chamfer and the vertical axis of the counterbore is between 30 degrees and 60 degrees between.
  • the upper surface of the bearing plate is provided with a recessed area in the area directly above the magnetic block, and the counterbore is located in the recessed area.
  • the diameter of the counterbore is 0.1-1.0 mm larger than the diameter of the magnet block.
  • the upper surface of the carrying plate and the lower surface of the stage are respectively provided with positioning structures that cooperate with each other.
  • the positioning structure includes protrusions respectively provided on the upper surface of the carrying plate and the lower surface of the stage, and the attraction of the magnetic block makes the protrusions abut against each other, thereby realizing automatic positioning.
  • the positioning structure includes mutually matched protrusions and grooves respectively provided on the upper surface of the carrying plate and the lower surface of the stage, the protrusions fall into the grooves, and the attraction of the magnetic block makes the side walls of the protrusions and the grooves Lean against each other to realize automatic positioning.
  • the outer contour of the orthographic projection of the projections and grooves on the carrying plate and the carrying table on the upper surface of the carrying plate or the lower surface of the carrying table is wedge-shaped.
  • the cross-sectional profile of the protrusions and grooves on the carrying plate and the carrying table on the carrying plate or the carrying table is a wedge shape or an inverted trapezoid with a wide upper and a narrow bottom.
  • the upper surface of the bearing plate is provided with a drainage channel in the area close to the magnetic block on the bearing plate.
  • the upper surface of the bearing plate is provided with a drain hole communicating with the recessed area, and the drain hole penetrates to the lower surface of the bearing plate.
  • the upper surface of the bearing plate is provided with a drain channel communicating with the counterbore, and the drain channel includes a drain hole penetrating to the lower surface of the bearing plate.
  • the drainage channel is provided with water-absorbent materials, and these water-absorbent materials are selected from: water-absorbent filter paper, sponge, nitrocellulose membrane and glass fiber membrane.
  • the present invention provides a transfer platform on a biological sample analyzer, which includes a movable carrying plate and a carrying platform on the carrying plate and separable from the carrying plate; the carrying platform and the carrying plate each include an upper surface And the lower surface, the lower surface of the stage and the upper surface of the bearing plate face each other; the upper surface of the stage is provided with a limit structure for fixing the detection element, the stage and the bearing plate are respectively provided with magnetic blocks, two The magnetic blocks of the carrier are arranged in a way of magnetic attraction; when the stage is placed in the pre-set area on the carrier board, the stage and the magnetic blocks on the carrier board are close to each other, so that the stage automatically Move to the designated position on the bearing plate.
  • stage on the conveying platform of the present invention may also include the limiting structure of the present invention.
  • the present invention also provides a biological sample analyzer, which includes a movement mechanism, an optical detection mechanism, and a transport platform for the biological sample analyzer described in the present invention driven by the movement mechanism.
  • the stage structure of the present invention can realize that under the premise of not moving the stage, especially under the premise of not turning the stage, it can carry test strips for testing, and can also carry a test board for testing.
  • the upper limit structure of the stage is a boss
  • the boss plays the role of supporting and limiting the test strip
  • the detection board is selected for detection
  • the boss acts as a detection board Due to the uneven arrangement of the bosses, the positioning function can play a limiting and foolproof effect, and prevent the detection board from being reversed.
  • the groove of the stage can not only accommodate and limit the test board, but also has a large space for holding urine, which can effectively reduce urine pollution.
  • the volume of the biological sample analyzer with the stage and the detection unit is reduced; in the detection process, the stage is avoided repeatedly turning over and the operation steps are reduced; at the same time, the stage can be detachably mounted on the motor driven
  • the rack board is convenient to enter and exit the biological sample analyzer, and it is easy to disassemble, so as to facilitate cleaning.
  • the transfer platform used for the analysis of the present invention adopts magnets arranged in an oppositely attracted arrangement, and is also provided with a positioning structure, it is only necessary to place the stage containing the detection reagents on the pre-set of the bearing plate during operation. Approximate position (no need for precise positioning). Under the precise guidance of the magnetic drive and positioning structure, the stage can automatically reach the precise position on the bearing plate to achieve automatic and precise positioning, so as to achieve the technical effect of blind placement. Therefore, the present invention has the advantages of simple operation, time-saving and labor-saving, and high working efficiency. At the same time, the present invention has simple structure, low cost, and is suitable for wide promotion.
  • Fig. 1 is a schematic diagram of the structure of the stage for the biological sample analyzer of the present invention.
  • Fig. 2 is a plan view of the stage for the biological sample analyzer of the present invention.
  • Fig. 3 is a schematic diagram of the detection board placed on the stage for the biological sample analyzer of the present invention.
  • Fig. 4 is a cross-sectional view taken along the line A-A in Fig. 3.
  • Figure 5 is a schematic diagram of the back of the detection board.
  • Fig. 6 is a schematic diagram of a test strip placed on the stage of the biological sample analyzer of the present invention.
  • Fig. 7 is a cross-sectional view taken along the line A-A in Fig. 6.
  • Fig. 8 is a schematic diagram of a detection unit of a biological sample analyzer.
  • Fig. 9 is a schematic diagram of a detection plate placed on the detection unit of the biological sample analyzer.
  • Figure 10 is a schematic diagram of a test strip placed on the detection unit of the biological sample analyzer.
  • Figure 11 is an exploded schematic view of the cooperation of the stage and the carrying plate.
  • Fig. 12 is a schematic diagram of a detection unit of a biological sample analyzer including another stage.
  • Fig. 13 is a schematic diagram of a detection board matched with the stage of Fig. 12.
  • Fig. 14 is a schematic diagram of a detection unit of a biological sample analyzer including another stage.
  • FIG. 15 is a three-dimensional schematic diagram of the carrier board in the first embodiment of the present invention, showing the upper surface structure of the carrier board.
  • Figure 16 is similar to Figure 15 but shows the magnet block in a precise location.
  • Figure 17 is a top view of the carrying plate and the stage after being combined.
  • Figure 18 is a cross-sectional view of Figure 17 along the line A-A.
  • FIG. 18A is a partial enlarged schematic diagram of FIG. 18 at position A.
  • FIG. 18A is a partial enlarged schematic diagram of FIG. 18 at position A.
  • FIG. 18B is a partial enlarged schematic diagram of FIG. 18 at position B.
  • FIG. 18B is a partial enlarged schematic diagram of FIG. 18 at position B.
  • FIG. 19 is a three-dimensional schematic diagram of the stage in the second embodiment of the present invention, showing the structure of the lower surface of the stage.
  • FIG. 19A is a partial enlarged schematic diagram of FIG. 19 at position A.
  • FIG. 19A is a partial enlarged schematic diagram of FIG. 19 at position A.
  • FIG. 19B is a partial enlarged schematic diagram of FIG. 19 at position B.
  • FIG. 19B is a partial enlarged schematic diagram of FIG. 19 at position B.
  • FIG. 20 is a three-dimensional schematic diagram of the carrier board in the second embodiment of the present invention, showing the upper surface structure of the carrier board (including magnetic blocks).
  • FIG. 20A is a partial enlarged schematic diagram of FIG. 20 at position A.
  • FIG. 20A is a partial enlarged schematic diagram of FIG. 20 at position A.
  • FIG. 20B is a partial enlarged schematic diagram of FIG. 20 at position B.
  • FIG. 20B is a partial enlarged schematic diagram of FIG. 20 at position B.
  • Fig. 21 is a partial cross-sectional view of the side view after the combination of Fig. 19 and Fig. 20, and the stage reaches the precise positioning position on the bearing plate.
  • FIG. 21A is a partial enlarged schematic diagram of FIG. 21 at position A.
  • FIG. 21A is a partial enlarged schematic diagram of FIG. 21 at position A.
  • FIG. 22 is a schematic diagram of the first arrangement scheme of the polarities of the magnetic blocks on the stage and the carrying plate.
  • FIG. 23 is a schematic diagram of the second arrangement scheme of the polarities of the magnetic blocks on the stage and the carrying plate.
  • FIG. 24 is a three-dimensional schematic diagram of the carrier board in the third embodiment of the present invention, showing the upper surface structure (without magnetic blocks) of the carrier board.
  • Fig. 24A is an enlarged schematic partial cross-sectional view of Fig. 24 along the line A-A direction.
  • FIG. 25 is a three-dimensional schematic diagram of the carrier board in the fourth embodiment of the present invention, showing the upper surface structure of the carrier board (without magnetic blocks).
  • Fig. 26 is a side cross-sectional view of the stage in the fourth embodiment of the present invention when the stage is placed in the initial position of the carrier plate.
  • FIG. 26A is a partial enlarged schematic diagram of FIG. 26 at position A.
  • FIG. 26A is a partial enlarged schematic diagram of FIG. 26 at position A.
  • Figure 27 is similar to Figure 26, but shows the precise positioning of the carrier plate.
  • FIG. 27A is a partial enlarged schematic diagram of FIG. 27 at position A.
  • FIG. 27A is a partial enlarged schematic diagram of FIG. 27 at position A.
  • FIG. 28 is a three-dimensional schematic diagram of the carrier board in the fifth embodiment of the present invention, showing the upper surface structure of the carrier board (without magnetic blocks).
  • FIG. 28A is a partial enlarged schematic diagram of FIG. 28 at position A.
  • FIG. 28A is a partial enlarged schematic diagram of FIG. 28 at position A.
  • FIG. 28B is a partial enlarged schematic diagram of FIG. 28 at position B.
  • FIG. 28B is a partial enlarged schematic diagram of FIG. 28 at position B.
  • Figure 29 is similar to Figure 28, but includes magnets.
  • Fig. 30 is a top plan view of Fig. 29;
  • FIG. 31 is a three-dimensional schematic diagram of the carrier board in the sixth embodiment of the present invention, showing the upper surface structure of the carrier board (without magnetic blocks).
  • FIG. 32 is a three-dimensional schematic diagram of the stage in the sixth embodiment of the present invention, showing the structure of the lower surface of the stage (including magnetic blocks).
  • Fig. 33 is a plan view (partial cross-sectional view) of the initial position after Fig. 31 and Fig. 32 are combined.
  • Figure 34 is similar to Figure 33, but shows that the stage has reached a precise position on the carrier plate.
  • Fig. 35 is a side sectional view of Fig. 34;
  • FIG. 36 is a three-dimensional schematic diagram of the carrier board in the seventh embodiment of the present invention, showing the upper surface structure of the carrier board (without magnetic blocks).
  • FIG. 37 is a three-dimensional schematic diagram of the stage in the seventh embodiment of the present invention, showing the structure of the lower surface of the stage (without magnetic block).
  • Fig. 38 is a top view of Fig. 37 and Fig. 38 combined.
  • Fig. 39 is a cross-sectional view taken along line A-A of Fig. 38, showing the initial position of the stage and the carrying plate after being combined.
  • Figure 40 is similar to Figure 39, but shows the precise positioning position of the stage and the carrier plate after being combined.
  • the present invention is used for the stage of a biological sample analyzer, which can place both a test board and test strips on the same surface (test strips for short. Test strips for short.
  • the detection board and the detection test strip are collectively referred to as the detection element).
  • the operator selects the test board or test strip according to the needs of the test item, and puts the test board or test strip on the stage to complete the detection and analysis of information on the test board and test strip to avoid frequent biological Take out or turn over the stage in the sample analyzer, which can improve the detection efficiency while effectively avoiding the operator's cumbersome operation and the error caused by the operation. Therefore, on the same side of the stage carrying the test strip, such as the front side, a detection board limiting structure is provided on the same side of the stage carrying the test strip, such as the front side.
  • the detection board limit structure makes the detection board be limited to the appropriate position of the stage, so that after the stage enters the biological sample analyzer, the detection result on the detection board is exactly in the detection area of the light source.
  • the detection board limiting structure is a boss matching the detection board, or a concave hole matching the detection board, or a groove for accommodating the detection board, or a combination of a boss and a groove, or a concave hole Combination with grooves.
  • a boss 111 is provided on the stage 100.
  • the boss 111 is used as a limit structure for the detection board.
  • the boss is used as a limit structure and cooperates with the detection board to limit the detection board 200 to position the detection board on the stage. The detection position.
  • the boss 111 also limits the position of the test strip on the stage, which can ensure that the test results on the test board and the test strip are exactly on the biological sample analysis
  • the appropriate light source detection area of the instrument ensures that the detection results on the detection board and test strips can be accurately read by the biological sample analyzer.
  • the boss is also used as a supporting structure to cooperate with the test strip to support the test strip 300 so that the test strip on the stage is on a substantially same plane.
  • the height of the boss on the stage is designed to ensure that the detection height of the test strip on the boss is the same as the detection height of the test strip in the detection board on the boss. In this way, whether the detection board or the test strip is located on the convex platform for detection, it can be located in the appropriate light source detection area of the biological sample analyzer to ensure that the detection results of the detection board and the test strip are accurately read.
  • the detection board 200 in the embodiment shown in FIG. 5 includes a bottom board 210 and a cover board 220.
  • the test strip for testing is installed on the bottom plate 210, and the cover plate 220 covers the bottom plate 210 and the test strip to form the test plate 200.
  • the back of the bottom plate 210 of the detection board is provided with a concave hole 211 corresponding to the boss 111, and the concave hole is a limiting structure on the detection board.
  • the size and position of the concave hole 211 on the detection board correspond to the convex platform 11 on the stage one by one. After the detection board 200 is positioned on the stage 100, the concave hole 211 is engaged in the boss 111 on the stage.
  • the number of the boss 111 is not limited, as long as it can be matched with the concave hole of the detection board so that the detection board can be placed on the correct detection position of the stage.
  • the number of bosses 111 is 1-5; in a specific embodiment, there are three bosses 111.
  • the number of the concave holes 211 of the detection plate can be the same as or different from that of the bosses 111 on the stage.
  • the number of concave holes 211 is the same as the number of bosses 111. For example, when the number of bosses 111 is three, the number of concave holes 211 is also three.
  • the number of concave holes 211 is different from the number of bosses 111, for example, when the number of bosses 111 is three, the number of concave holes 211 is also four, three of which correspond to the bosses, and the remaining one is concave.
  • the hole can be used for other purposes or is idle when matched with the stage.
  • the bosses on the stage can be arranged evenly.
  • the uneven arrangement of the bosses 111 is used to identify and limit the direction of the detection board 200 on the stage 100 to ensure that the direction in which the detection board 200 is placed on the stage 100 will not be wrong. . Avoid inaccurate or undetectable detection results caused by the detection board 200 being reversed or the detection board deviates from the light source detection area of the biological sample analyzer.
  • specific methods include but are not limited to: the bosses 111 are not arranged on the same straight line; or, the spacing between the bosses 111 is different.
  • the line between the centers of the two bosses is not parallel to the horizontal or vertical central axis of the detection board; for another example, when there are three or more bosses, the adjacent The spacing between the two bosses 111 is not the same; or three or more bosses 111 are not arranged on a straight line.
  • the arrangement of the concave holes 211 on the back of the detection board bottom plate 210 is the same as the arrangement of the boss 111 on the stage 100.
  • the concave holes 211 are arranged on a straight line with different intervals, and the interval between the concave holes 211 and the interval between the bosses 111 correspond to the same one-to-one correspondence.
  • the concave holes 211 are arranged on the center line of the bottom plate 210.
  • the recessed hole 211 on the back of the bottom plate 210 may or may not penetrate the entire bottom plate 210.
  • the area of the stage 100 where the detection board is stored is provided with a groove 110, and the groove 110 of the stage is used to accommodate and limit the detection board.
  • the boss 111 In the groove 110 That is, the boss and the groove are combined to limit the detection board.
  • the groove forms a large space for holding urine, it can accommodate the urine overflowing from the test strip 300 or the detection plate 200. On the one hand, the urine collected in the groove will not flow out of the stage and cause pollution to the environment.
  • the bottom of the groove has a certain distance from the test strip or the test board placed on the boss, the collection The overflow urine at the bottom of the groove cannot touch the test strip or the test board, so as to prevent different urine samples from contaminating the test strip or the test board being tested.
  • two side walls of the groove 110 are provided with protruding strips 112 protruding from the side walls; the position of the protruding strips 112 is adjacent to the end of the groove 110; the spacing between the protruding strips 112 on the two side walls is equal to Detect the width of the board 200.
  • the protruding strips 112 on the two side walls contact and engage with the side walls of the detection board 200 so that the detection board 200 is better fixed in the groove 110.
  • One or more protruding strips 112 are provided on both side walls near the two ends of the groove 110.
  • the positions of the convex strips 112 arranged on the two side walls of the groove 110 are symmetrical.
  • a recess 230 is provided in the middle of the two side walls of the bottom 210 and the cover 220 of the detection board, such as a symmetrical design. ⁇ 230 ⁇ The depression 230.
  • the space formed by the recess can facilitate the operator's fingers or the gripper of the mechanical arm to extend into the recess to grab the detection board.
  • the detection plate limiting structure on the stage is a concave hole 111', and the arrangement and arrangement of the detection plate refer to the arrangement and arrangement of the aforementioned boss 111.
  • the back of the bottom plate of the detection board 200' is provided with a detection board protrusion 211' that matches with the stage recess 111', and the number and arrangement of the detection board protrusions 211' are the same as those of the stage recess.
  • the detection board protrusion 211' on the detection board 200' is inserted into the stage recess 111' on the stage 100' in a one-to-one correspondence Inside, the detection board 200' is confined on the stage 100'.
  • the section of the boss or the concave hole of the limiting structure can be of different shapes.
  • two of the bosses can be square, and the shape of the third boss is circular.
  • the concave holes on the matching detection board are also square and circular respectively.
  • the test strip 300 in the embodiment shown in FIG. 8 includes a substrate 301 on which a detection test paper 302 is pasted.
  • the test paper may be a urine union test paper, a lateral flow test paper, or the like.
  • a test strip positioning structure is provided on the stage.
  • the positioning structure of the positioning test strip on the stage is a card slot or a protruding nail.
  • the positioning structure of the test strip is a protruding nail, it is matched with it, and a test strip hole is provided on the test strip.
  • the test strip is locked and positioned by the card slot, or the test strip hole is matched with the protruding nail on the stage to make the test strip positioned.
  • the test strip positioning structure on the stage 100 is a card slot, and there are two card slots, the first card slot 120 and the second card slot 130, corresponding to the test strip The ends.
  • the first card slot 120 and the second card slot 130 are respectively provided at both ends of the groove 110 to position and support the test strip 300.
  • the first slot 120 is located at one end of the stage 100 to facilitate the insertion of the test strip 300 into the stage 100 from the end of the stage 100.
  • the center of the boss 111 and the center of the first slot 120 and the center of the second slot 130 are located on the same straight line. That is, when the test strip 300 is located on the stage 100, both ends of the test strip 300 are respectively located in the first slot 120 and the second slot 130, and the boss 111 is located directly below the test strip 300 .
  • the area of the groove 110 is placed on the test board 200, and the grooves 120 and 130 are placed on both ends of the test strip.
  • the depth of the groove 110 is greater than the first The depth of the card slot 120 and the second card slot 130, so that when the test strip and the test board are placed on the stage, the test strip and the test result area on the test board can be located at the same height and located in a suitable light source Area.
  • the height of the boss 111 in the groove 110 is the same as the height of the first groove 120 and the second groove 130 higher than the groove 110; or , The groove 110 has the same depth as the grooves 120 and 130, so it is easy to form one piece during production.
  • the first groove 120 and the second groove 130 are provided with protrusions 122 and 132.
  • the height of the protrusions 122 and 132 is the same as that of the groove
  • the height of the boss 111 in the slot is the same, so that the test strip 300 in the slot and the groove is in a horizontal state.
  • the widths of the first slot 120 and the second slot 130 are the same as the width of the test strip 300, so that the slot can better engage and position the test strip.
  • openings 121 are provided at both ends of the first card slot 120; the width of the opening 121 is the same as the width of the test strip 300.
  • the first slot 120 is fixed to one end of the test strip 300 by engaging the side wall of the test strip 300 at the opening 121 of the first slot.
  • one end of the second slot 130 has an opening 131; the opening 131 is provided with a symmetrical protrusion 133.
  • two side walls at the end of the second slot 130 are provided with symmetrical protrusions 133.
  • the distance between the protrusion 133 at the second slot opening 131 and the side wall protrusion 133 is the same as the width of the test strip 300.
  • the protrusion 133 at the opening and the protrusion 133 on the side wall contact the side wall of the test strip 300 so that the other end of the test strip is fixed in the second slot 130.
  • the test strip positioning structure provided on the same surface of the stage 100' and the concave hole is a protruding nail 314', and the protruding nail 314' is connected to the concave hole 111' of the carrier. Located in a straight line.
  • a test strip hole 301' is provided on the test strip 300'. After the test strip 300' is on the stage 100', the test strip hole 301' is sleeved on the protruding nail 314', so that the test strip 300' is positioned.
  • the test strip positioning structure may also include a first card slot 120 and a second card slot 130.
  • the protruding nail 314' is located in the first card slot 120 and the second card slot 130, and passes through the first card slot 120 and the second card slot.
  • the two card slots 130 cooperate with the protruding nail 314' to position the test strip 300' together.
  • the positioning structure of the test strip may also be a combination of the slot 120, 130 and the protruding nail 314', so that the test strip 300' is fixed more firmly.
  • the limit structure on the stage 100" is a boss 111, which corresponds to the limit structure type concave hole 211 of the detection plate 200.
  • the test strip on the stage 100" is positioned The structure is a protruding nail 314', and the corresponding positioning structure of the test strip 300' is a test strip hole 301'.
  • the detection board and the test strip can also be called the detection device, and the detection board limit structure and the test strip positioning structure can also be called the detection device fixing structure.
  • a biological sample analyzer for biological sample analysis includes a stage and a detection unit.
  • the stage 100 is used in a biological sample analyzer. Specifically, the stage 100 is used to be placed in the detection unit 10 of the biological sample analyzer, and the detection plate 200 or the test strip 300 is brought into the detection unit 10 , The detection and analysis function of the biological sample analyzer is realized through the information reading and analysis feedback of the detection board 200 or the test strip 300 by the detection unit 10, as shown in Figs. 8-14.
  • the detection unit 10 includes a stage, a stage transport platform, a movement mechanism, and an optical detection mechanism. More specifically, the detection unit 10 includes a stage 100 or 100' or 100", a transport platform includes a carrier plate 400, a movement mechanism includes a motor 600 and a gear 700, and an optical detection mechanism includes a light source (such as a hexagonal head 900) and a detection photoelectric PCB Board 800.
  • the hexagonal head is a light path detection channel, surrounded by 6 LED lights, the middle is the PD receiving channel, which is assembled with the detection photoelectric PCB board, and then installed on the gantry bracket.
  • Motor 600 and gear 700 The gear 700 meshes with the carrier board 400.
  • the gear 700, the hexagonal head 900 and the detection photoelectric PCB board 800 are all connected to the gantry support 500.
  • the motor 600 drives the gear 700 to rotate, and the gear 700 drives the carrier board 400 through gear meshing.
  • the linear reciprocating motion on the gantry bracket 500 finally drives the stage 100 on the carrying plate 400 to enter and exit linearly in the gantry bracket 500; thus, the stage 100 enters the gantry bracket 500, and the hexagonal head 900 and the detection photoelectric PCB board 800 cooperate to read Take the information on the test board 200 or the test strip 300 on the stage 100; and realize that the stage 100 leaves the gantry support 500, so that the test board 200 or the test strip 300 on the stage 100 can be replaced, and Take the function of cleaning the download stage 100.
  • the stage 100 is placed on the carrier plate 400.
  • the stage 100 is detachably fixed on the carrier plate 400.
  • the carrying plate 400 and the stage 100 are attracted by the magnetic block to achieve the detachable assembly of the carrying plate and the stage.
  • the two ends of the back of the stage are provided with magnetic holes, namely the first magnetic hole 102 and the second magnetic hole 102'; on both ends of the carrier plate are provided with magnetic holes, which are the first magnetic hole 401 and the second magnetic hole.
  • the second magnetic hole 402' A magnetic block 101 is installed in the first magnetic hole 102, and a magnetic block 101' is installed in the second magnetic hole 102'.
  • a magnetic block is also pressed into the magnetic hole 402 (the magnetic block is not shown in the figure) .
  • the two magnetic blocks 101 and 101' in the first magnetic hole 102 and the second magnetic hole 102' on the stage have opposite magnetic properties on the side facing the carrier plate.
  • the magnetic block 101 in the first magnetic hole 102 faces One side of the bearing plate is S pole
  • the side of the magnetic block 101' in the second magnetic hole 102' facing the bearing plate is N pole.
  • the magnetism of a magnetic block and the magnetism of the magnetic block are attracted to the magnetic surface of the magnetic block on the back of the stage, which corresponds to the first magnetic hole 102 of the stage.
  • the magnetic block is pressed into the first magnetic hole 401 of the carrier plate, and the side of the magnetic block facing the carrier is N pole.
  • the second magnetic hole 402' of the carrier plate corresponding to the second magnetic hole 102' of the carrier is internally pressed Into the magnetic block, the magnetic block on the side of the magnetic block facing the stage is an S pole. According to the principle of magnetic repulsion of the same sex and attraction of the opposite sex, the stage can only be placed on the carrier board with 102 corresponding to 402 and 102' corresponding to 402', so that the magnetic blocks in the magnetic hole are attracted to each other.
  • the detection board 200 of this embodiment takes an HCG detection board as an example, and a test paper for detecting HCG is placed in the detection board.
  • the test strip 300 in this embodiment is an example of a urine test strip for routine urine testing, such as a urine 11 test strip, a urine 12 test strip, and the like.
  • the stage 100 moves out of the gantry bracket 500 under the drive of the carrier plate 400, and the detection plate 200 is placed in the groove 110 of the stage.
  • the concave hole 211 of the detection plate 200 and the boss 111 in the groove are engaged in a one-to-one correspondence, and a urine sample is added to the sample loading hole of the detection plate.
  • the hexagonal head 900 and the detection photoelectric PCB board 800 read and analyze the detection information on the detection board 200.
  • the motor 600 drives the carrying plate 400 to drive the stage 100 to move away from the gantry bracket 500, and the detection plate 200 is removed.
  • the stage 100 is driven by the carrying plate 400 to move out of the gantry bracket 500, and is placed in the first slot 120 and the second slot 130 of the stage
  • the test strip 300 is such that the test strip 300 is clamped in the first slot 120 and the second slot 130, and at the same time, the middle part of the test strip 300 is positioned on the boss 111 to obtain support.
  • the hexagonal head 900 and the detection photoelectric PCB board 800 read and analyze the detection information on the test strip 300.
  • the motor 600 drives the carrying plate 400 to drive the stage 100 to move away from the gantry support 500, and the test strip 300 is removed.
  • the stage of the present invention can not only put a test strip of urinary union for testing, but also put an HCG board for testing. There is no need to move the stage during the conversion process between the urinalysis test paper and the test board.
  • the motor 600 drives the stage 100 to move to the gantry bracket 500 for storage.
  • the stage 100 needs to be cleaned, the carrier plate 400 and the stage 100 are moved out of the gantry bracket 500 by the motor 600, and the stage 100 is removed from the carrier plate 400 for cleaning. After the cleaning is completed, pass through The magnetic attraction connects the magnetic block 101 of the stage and the magnetic block 401 of the carrier plate together by corresponding adsorption. Then the motor 600 moves the bearing plate 400 and the stage 100 into the gantry bracket 500.
  • the present invention also provides a transport platform for an analyzer, which includes a movable carrier plate 400 and a carrier table 100.
  • the carrying plate 400 is driven by a motor 600, a gear 700, etc., and can move back and forth.
  • the stage 100 is placed on the carrier board 400 and can be separated from the carrier board 400.
  • the side of the carrier board 400 facing the stage 100 is the upper surface 410, and the opposite side is the lower surface 411.
  • the side of the stage 100 facing the carrier plate 400 is the lower surface 151, and the opposite side is the upper surface 152 (FIG. 19).
  • the stage 100 and the carrier plate 400 are respectively provided with magnetic blocks 101 and 401 that are magnetically attracted.
  • the suction of the magnetic blocks 101 and 401 causes the stage 100 to automatically move to a designated position on the carrying plate 400, thereby realizing the relative position of the stage 100
  • the bearing plate 400 is automatically positioned.
  • the upper surface 410 of the carrier board 400 is in the area close to the magnetic blocks 401, 401' on the carrier board, preferably directly above the two magnetic blocks 401, 401' on the carrier board, respectively, with recessed areas 412, 413 respectively (Shown in Figure 18A and Figure 18B).
  • the contours of the recessed areas 412 and 413 are rectangular, square, circular or elliptical (only rectangles are shown in FIGS. 15 and 16 and other shapes are omitted), and the area is larger than the outer contour of the magnetic block 101 in the stage 100.
  • the magnetic blocks 101, 101' in the stage 100 still have movable space in the recessed areas 412, 413 of the upper surface 410 of the carrier plate 400, and do not need to be placed in precise positioning positions.
  • the magnetic blocks in the stage 100 and the bearing plate 400 are as close as possible to each other, thereby driving the stage 100 and the bearing plate 400 to automatically and accurately position, thereby achieving the technical effect of blind placement.
  • the contours of the recessed areas 412, 413 are rectangular, square, circular or elliptical, and their area is larger than the outer contours of the magnetic blocks 101, 101' in the stage 100, it is easy to place the The magnetic blocks 101 and 101' are respectively placed in the recessed areas 412 and 413, so the operation is very convenient.
  • the transport platform for the analyzer of the present invention includes two pairs of magnetic blocks 101, 101' (arranged along the longitudinal direction of the carrier table 100 and the carrier plate 400, respectively, at an appropriate distance from each other.
  • the two magnetic blocks 101, 101' on the stage 100 have opposite polarities in the same direction (for example, the vertical downward direction); the two magnetic blocks 401, 401' on the carrier plate 400 are in the same direction (for example, the vertical downward direction).
  • the polarity of the direction) is also opposite; therefore, the magnetic blocks on the stage 100 and the corresponding magnetic blocks on the carrier plate 400 are arranged in an opposite sex attraction (the arrangement is as follows).
  • Figures 22 and 23 show two magnetic arrangement schemes of the magnetic block on the stage and the carrier board (this arrangement scheme is applicable to all embodiments).
  • FIG. 19-21A is the second embodiment of the present invention.
  • the difference between this embodiment and the first embodiment is that the upper surface 410 of the carrying plate 400 and the lower surface 151 of the stage 100 are respectively provided with positioning structures that cooperate with each other.
  • the positioning structure includes vertical walls 416 and 153 respectively provided on the upper surface 410 of the carrying plate and the lower surface 151 of the stage.
  • the axis of the magnetic block on the carrier plate 400 and the stage 100 are not coincident, but offset by a distance F between 0.5-3.0 mm. Therefore, the magnetic blocks 101 and 401 are mutually Attracting, urges the vertical walls 416 and 153 to keep abutting. Such a design can ensure that the stage 100 is positioned on the carrier plate 400 more accurately.
  • Figures 24 and 24A is the third embodiment of the present invention.
  • the difference between this embodiment and the first embodiment is that the recessed areas 412 and 413 on the surface 410 of the carrier plate are replaced with two contour dimensions corresponding to the contour dimensions of the magnetic block 101 protruding from the lower surface 151 of the carrier plate.
  • Counterbore 414, 414' (as shown in Figure 24).
  • the upper surface 410 of the carrying plate is provided with counterbores 414, 414' directly above the two magnetic blocks 401, 401', which are adapted to the shape of the two magnetic blocks 101, 101' fixed on the stage.
  • the magnetic block 101' on the stage at least partially protrudes from the lower surface 151 of the stage, and can at least partially enter the counterbore 414', but try to limit the magnetic block 101' on the stage from sinking.
  • the inside of the hole 414 ′ shakes in a direction parallel to the upper surface 410 of the stage.
  • the magnetic block 101' on the stage is a cylinder, and the contour of the counterbore 414' on the carrier plate is also a cylinder.
  • the diameter of the counterbore 414' is 0.1-1.0 mm larger than the diameter of the magnet 101'.
  • the uppermost opening of the counterbore 414' is provided with a larger size
  • the cone is chamfered to guide the hole 418.
  • the depth L of the chamfer is 0.3-2.0 mm
  • the angle a between the chamfer and the vertical axis of the counterbore is between 30 degrees and 60 degrees (preferably 40 degrees). It should be noted that in other solutions of this embodiment, the uppermost opening of the counterbore 414, 414' may not include the cone chamfering guide hole 418.
  • Figures 25-27A is the fourth embodiment of the present invention.
  • the upper surface 410 of the bearing plate is provided with a slope passage 415 communicating with the counterbore 414, and the slope passage 415 is from a position farther from the counterbore 414 to closer to the counterbore 414 The position gradually descends (the corresponding ramp channel 415' on the other side has a similar structure and will not be repeated here).
  • the magnetic blocks on the stage 100 follow the ramp channels 415, 415' under the suction force of the magnetic blocks. It slides into the counterbore 414, 414' and the side wall of the counterbore 414, 414' respectively approximately in the longitudinal direction of the carrier plate 400, so as to achieve precise positioning (shown in FIG. 27A).
  • FIGS. 28-30 is the fifth embodiment of the present invention.
  • This embodiment combines the structures of the first embodiment and the third embodiment, that is, the design includes both the recessed area 412 and the counterbore 414, and the counterbore 414 is located in the recessed area 412.
  • the magnetic block on the stage 100 automatically slides under the suction force of the magnetic block. It enters into the counterbore 414 and abuts against the side wall of the counterbore 414 to achieve precise positioning (as shown in FIGS. 29 and 30).
  • the upper surface 410 of the carrier board is provided with the area close to the magnetic blocks 401, 401' on the carrier board, respectively, which communicate with the counterbores 414, 414'.
  • the drainage channels 419, 419' are used to drain the liquid (such as urine) that has leaked here in time.
  • the drain channel 419 further includes a drain hole 420.
  • the bottom of the drain hole 420 is lower than the bottom of the drain channel 419, but does not penetrate the lower surface 411 of the carrier plate.
  • the drain hole 420 penetrates to the lower surface 411 of the carrier plate.
  • a water-absorbing material can also be placed at the bottom of the counterbore 414, 414' to absorb the liquid leaking there. It is also possible to arrange a water-absorbing material in the drain channel 419 and/or the drain hole 420 to absorb the liquid leaking there.
  • These water-absorbing materials are selected from: water-absorbing filter paper, sponge, nitrocellulose membrane and glass fiber membrane.
  • the design of the drain channel 419 and the drain hole 420 is not only applicable to the fifth embodiment, but also applicable to other embodiments.
  • the upper surface 410 of the bearing plate is provided with a drain hole 420 communicating with the recessed area, and the drain hole 420 penetrates or does not penetrate to the lower surface 411 of the bearing plate.
  • the upper surface 410 of the bearing plate is provided with a drain channel 419 communicating with the counterbore 414, 414', the drain channel 419 includes a drain hole 420, the drain hole 420 penetrates or does not penetrate to the bearing plate Lower surface 411.
  • the positioning structure includes mutually matched protrusions 154 and grooves 417 respectively provided on the upper surface 410 of the carrying plate and the lower surface 151 of the stage.
  • the protrusions 154 fall into the grooves 417, and the magnetic block
  • the suction force causes the side walls of the protrusion 154 and the groove 417 to abut against each other, thereby realizing automatic positioning.
  • the outer contours of the orthographic projection of the projections 154 and grooves 417 on the carrier plate 400 and the stage 100 on the upper surface 410 of the carrier plate or the lower surface 151 of the stage are wedge-shaped.
  • the protrusion 154 is placed in the groove 417 under the suction force of the magnetic block.
  • the carrier plate 400 slides in the longitudinal direction (the X direction shown in FIG. 33) until the side walls of the protrusion 154 and the groove 417 abut against each other, thereby achieving precise positioning (as shown in FIGS. 34 and 35).
  • the figure shows that the protrusion 154 is designed on the stage 100 and the groove 417 is designed on the carrier plate 400, it is also possible to design the protrusion 154 on the carrier plate 400 and the groove 417 on the carrier plate 400.
  • stage 100 On stage 100.
  • Figures 36-40 which is the seventh embodiment of the present invention.
  • the cross-sectional profile of the protrusions 154' and recesses 417' on the carrying plate and the carrying table is a wedge shape with a wide upper and a narrow bottom or an inverted profile. Trapezoid.
  • the protrusion 154' slides into the groove 417' in a direction substantially perpendicular to the upper surface 410 of the carrier plate. , So as to guide the stage 100 to automatically reach the precise positioning position on the carrier plate 400.
  • the figure shows that the protrusion 154' is designed on the stage 100 and the groove 417' is designed on the carrier plate 400, it is also possible to design the protrusion 154' on the carrier plate 400, and the groove 417' Designed on the stage 100.

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Abstract

本发明涉及一种用于分析仪的传送平台,包括可移动的承载板和载物台,载物台被放置在承载板上并且可与承载板分离。承载板之面向载物台的那一面为上表面,相反面为下表面。载物台之面对承载板的那一面为下表面,相反面为上表面。载物台和承载板上分别设有磁性相吸的磁块。当载物台被放置在承载板上预先设定的区域内时,磁块的吸力使载物台相对承载板自动定位,从而达到盲放的技术效果。本发明可应用于特定蛋白、胆固醇、血红素、尿常规、干式生化等的检测分析仪。本发明具有操作简便、省时省力、工作效率高等优点。同时,本发明结构简单,成本低廉,适合广泛推广。

Description

生物样品分析仪用的载物台、传送平台和生物样品分析仪 技术领域
本发明属于医学检测领域,涉及生物样品分析仪及其配件,特别是生物样品分析仪用的载物台、传送平台和生物样品分析仪。
背景技术
尿液分析仪作为生物样品分析仪的一种,是用于测定尿液中生理指标的。一般的,将浸有尿液的测试条或测试卡(本发明将其又可称为“生物样品检测试剂”或者简称为“检测试剂”)置于载物台上并被运输至检测位以被仪器读取检测结果。一台仪器要实现测试条和测试卡两种测试装置均可使用,目前有三种实现方案。
第一种方案是将测试条或测试卡分别放在各自对应的托架上,再将托架置于通用的载台上。如美国专利US7118713的尿液分析仪,操作人员在将测试条或测试卡替换为测试卡或测试条时,需要同时将托架也进行更换,操作步骤繁琐,并且载台上设有托架的放置位会形成清洗死角。
第二种方案是在载台上设置有测试卡放置位,对测试条托架进行外形尺寸加工,使其也可以放入测试卡放置位,如美国专利US6239445的尿液分析仪。该方案相较于上述第一种方案虽然少了一个测试卡托架,但仍然需要在使用过程中对托架进行反复更换。
第三种方案是将载台作两面设计,一面为测试条放置位,另一面为测试卡放置位。这种载台通常需要较大体积,占用的空间比较大。在更换测试类型时,操作人员需先对载台已使用过的一面进行清洗、干燥,再将使用过的一面与仪器相连接,未使用过的一面用来放置测试卡或测试条。这类载物台正反两面可放置不同类型检测装置(测试卡或测试条)的尿机,当更换检测装置类型时,需取下载物台,清洗后再放入仪器中,操作步骤复杂。
现有的载物台设计,会存在仪器体积大、操作步骤多、清洗难度大、使用不方便等问题。
此外,当测试卡放到载物台上后,需要确保测试卡能在检测仪器内精确定位,使仪器光学检测部件能精准地对准测试卡的检测区,获得准确的测试结果。如果测试卡在检测仪器内定位不准,那么,检测仪器上的光学检测部件发出的主动光源就不能精准地照射检测区,造成检测结果不准确或报错。虽然有些现有技术能够准确地定位,但是定位过程繁琐,费时费力,工作效率低。因此,需要一种既定位准确又操作方便快捷的具有载物台的的生物样品分析仪。
发明内容
本发明提供一种生物样品分析仪用的载物台,该载物台在生物样品分析仪中起到传送检测装置的作用,所述载物台无需翻转载物台的情况下,即可实现在同一个载物台的同一面选择放置试纸条或测试卡(又可称为检测板),以分别完成采用试纸条检测的项目或采用测试卡检测的项目。同时,还提供与该载物台配套使用的检测板和试纸条。简化了检测步骤,提高检测效率,降低检测出错的风险。
本发明提供的一种生物样品分析仪用的载物台,所述载物台承载检测装置的一面上设有检测装置限位结构。
载物台上承载试纸条的一面设有检测板限位结构,所述限位结构能将检测板固定在载物台上,并保证检测板放置方向的准确。
一些优选的实施方式中,检测板限位结构为与检测板配合的凸台,或者与检测板配合的凹孔,或者容纳检测板的凹槽,或者凸台与凹槽的结合,或者凹孔与凹槽的结合。
当检测板限位结构为凸台时,凸台除了与检测板配套将检测板限位在载物台上,还可起到对试纸条在载物台上的位置进行限位,确保检测板或试纸条上的检测结果区正好位于生物样品分析仪的光源检测区域,保证检测结果能够被生物样品分析仪准确读取。同时,凸台还兼具支撑试纸条的作用,特别是被样品浸湿的试纸条会因重量增加而易发生变形,导致检测结果区域 也变形,导致检测结果不能被准确采集。因此,试纸条被支撑尤为重要。当检测板限位结构为凹孔时,凹孔除了与检测板配套对检测板进行载物台上的限位,还对试纸条在载物台上进行限位,使检测板和试纸条均位于合适光源检测区内。当检测板限位结构为容纳检测板的凹槽时,通过凹槽对检测板进行限位,使检测板位于合适光源检测区内。
一些优选的实施方式中,凸台高度保证位于凸台上的试纸条检测高度和位于凸台上的检测板内的试纸条检测高度相同。这样,能够使检测板的检测结果和试纸条的检测结果都位于生物样品分析仪的合适的光源检测区域,从而保证检测板和试纸条上的检测结果能够被生物样品分析仪准确读取。
一些优选的实施方式中,凸台或者凹孔在载物台上为不均匀排布,起到防呆作用。
这种不均匀排布的方式可用于识别检测板放置在载物台上的方向。凸台不均匀排布的方式选自以下方式或不同方式的组合,但不限于此所列,比如,不排列在同一条直线上、凸台之间的间距不相同、凸台到凹槽端部的间距不相同、凸台到凹槽端部的距离与凸台之间的间距不同。
一些优选的实施方式中,凸台或者凹孔的数量为一个及以上。更优选的,例如三个或三个以上。
一些优选的实施方式中,凸台或凹孔位于凹槽内。既可以通过凹槽来容纳和限定检测板,又可以通过凸台进一步限位检测板的位置。
一些优选的实施方式中,凸台为三个,位于凹槽内,三个凸台不均匀排布。具体的,三个凸台之间为间距不相同的不均匀排布。
一些优选的实施方式中,载物台上还设有试纸条定位结构。
一些优选的实施方式中,试纸条定位结构为位于载物台两端的卡槽或者凸钉,或者卡槽与凸钉的结合。
一些优选的实施方式中,位于载物台两端的卡槽为第一卡槽和第二卡槽。两个凸钉分别位于第一卡槽和第二卡槽内
一些优选的实施方式中,凸台中心与第一卡槽中心以及第二卡槽中心位于同一直线上。第一卡槽和第二卡槽用于安置和固定试纸条,其定位试纸条作用。而凸台中心与第一卡槽中心以及第二卡槽中心位于同一直线上,使凸台成为试纸条的底部支撑。
一些优选的实施方式中,第一卡槽和第二卡槽位于容纳检测板的凹槽的两端。
一些优选的实施方式中,位于凹槽内三个凸台分布在一条直线上,并且,凸台的中心线与第一卡槽和第二卡槽的中心线重合。
一些优选的实施方式中,因检测板的厚度通常大于试纸条的厚度,容纳检测板的凹槽深度大于安置试纸条的第一卡槽和第二卡槽的深度,这样保证检测板的检测结果与试纸条的检测结果处于同一高度。
同样的,为了保证检测板的检测结果区与试纸条的检测结果区处于同一高度,一些优选的实施方式中,第一卡槽和第二卡槽内均设有支撑试纸条的凸块,所述凸块高度与凸台高度相同。
一些优选的实施方式中,第一卡槽和第二卡槽宽度与试纸条宽度相同,以更好地固定试纸条。
一些优选的实施方式中,为了更优的限定试纸条,所述第一卡槽两端开口;所述开口宽度与试纸条宽度相同;第二卡槽一端开口;开口处设有对称的凸起;第二卡槽末端两侧壁设有对称的凸起;第二卡槽开口处凸起和侧壁凸起之间的间距与试纸条宽度相同。
一些优选的实施方式中,为了使检测板位于凹槽内被更好的固定,所述凹槽两侧壁设有突出于侧壁的凸条;所述凸条邻近凹槽的端部;两侧壁的凸条之间的间距等于检测板宽度。
本发明还提供用于生物样品分析仪中进行检测的检测板,该检测板具有与载物台结构相配套的结构。具体的,检测板包括底板和盖板,底板的背面设有与载物台上的检测板限位结构相配套的限位结构。
一些优选的实施方式中,底板背面的限位结构为凹孔或凸起。
具体的,凹孔或凸起为一个及以上。当底板背面的限位结构为凹孔时,凹孔与载物台上的凸台相对应,并且,二者大小、形状以及位置均一一对应。检测板放置到载物台上时,检测板上的凹孔一一对应卡合到载物台的凸台上,从而实现检测板的固定,以及检测板方向的确定。同理,将底板背面的限位结构为凸起时,载物台对应的设置凹孔,同样能实现检测板的固定,以及检测板方向的确定。
一些优选的实施方式中,检测板上的凹孔或凸起为三个及以上;凹孔或凸起为不均匀排布。检测板上的凹孔或凸起不均匀排布的方式也与载物台上的凸台或凹孔的不均匀排列方式相对应。
一些优选的实施方式中,凹孔或凸起位于底板中心线上。
一些优选的实施方式中,检测板上的底板和盖板两个侧壁中间位置处设有对称的凹陷。
本发明还提供一种生物样品分析仪的检测单元,包括运动机构和光学检测系统,以及本发明中所述的载物台和载物台运送平台。
一些优选的实施方式中,所述载物台运送平台为齿条板,载物台可拆卸式地安装在齿条板上。
本发明还提供一种生物样品分析仪,包括检测单元,该检测单元包括运动机构和光学检测系统,还包括本发明所述的载物台和载物台运送平台。
本发明提供一种生物样品分析仪用的传送平台,包括可移动的承载板和载物台,载物台被放置在承载板上并且可与承载板分离;承载板面向载物台的那一面为上表面,相反面为下表面;载物台面对承载板的那一面为下表面,相反面为上表面;载物台和承载板上分别设有磁性相吸的磁块,当载物台被放置在承载板预先设定的区域内时,磁块的吸力使载物台相对承载板自动定位。
进一步的:用于分析仪的传送平台包括两对彼此间隔适当距离的磁块,载物台上的两个磁块在同一方向的极性相反,承载板上的两个磁块在同一方向的极性相反,载物台上的磁块和承载板上对应的磁块呈异性相吸排布。
进一步的:承载板上表面在靠近磁块的区域设有凹陷区;当载物台上的磁块在承载板上的正投影位于该凹陷区时,磁块的吸力使载物台相对承载板自动定位。
进一步的:承载板上表面在其磁块的正上方区域设有凹陷区,当载物台被放置在承载板上时,载物台上的磁块位于该凹陷区内。
进一步的:承载板上的凹陷区的轮廓为矩形、正方形、圆形或者椭圆形,其面积大于安装在载物板上之磁块的底面面积,载物台上之磁块为圆柱形,其在凹陷区内有活动的空间。
进一步的:载物台上的磁块至少部分凸出于载物台的下表面,并进入承载板上的凹陷区内。
进一步的:承载板之上表面和载物台之下表面分别设有相互配合的竖墙,当载物台被放置在承载板上预先设定的区域内时,磁块的吸力使载物台和承载板上的竖墙相互抵靠。
进一步的:承载板和载物台上的磁块的轴线相互偏移0.5-3.0毫米。
进一步的:载物台上的磁块至少部分凸出于载物台的下表面,承载板在其上表面设有沉孔,载物台上凸出的磁块落入承载板上的沉孔,并且抵靠沉孔的孔壁,从而实现自动定位。
进一步的:承载板上表面设有一段与沉孔连通的斜坡通道,斜坡通道从离沉孔较远位置处向离沉孔较近位置处逐渐下降。进一步的:沉孔的最上端开口处设有尺寸更大的圆锥体倒角引导孔,倒角的深度为0.3‐2.0毫米,倒角与沉孔垂直轴线的夹角介于30度到60度之间。
进一步的:承载板之上表面在其磁块的正上方区域设有凹陷区,沉孔位于该凹陷区内。
进一步的:沉孔的直径比磁块的直径大0.1‐1.0毫米。
进一步的:承载板的上表面和载物台的下表面分别设有相互配合的定位结构。
进一步的:定位结构包括分别设置在承载板之上表面和载物台下表面的凸起,磁块的吸力使这些凸起相互抵靠,从而实现自动定位。
进一步的:定位结构包括分别设置在承载板上表面和载物台下表面的相互配合的凸起和凹槽,凸起落入凹槽内,磁块的吸力使凸起和凹槽的侧壁相互抵靠,从而实现自动定位。
进一步的:承载板和载物台上的凸起和凹槽在承载板上表面或者载物台下表面上的正投影的外轮廓为楔形。
进一步的:承载板和载物台上的凸起和凹槽在承载板或者载物台之横截面的轮廓为上宽下窄的楔形或者倒梯形。
进一步的:承载板上表面在靠近承载板上之磁块的区域设有排液渠。
进一步的:承载板上表面设有与凹陷区连通的排液孔,所述排液孔贯穿至承载板下表面。
进一步的:承载板上表面设有与沉孔连通的排液渠,所述排液渠包括贯穿至承载板下表面的排液孔。
进一步的:所述排液渠内设有吸水性材料,这些吸水性材料选自于:吸水性滤纸、海绵、硝化纤维膜和玻璃纤维膜。
进一步的,本发明提供了一种生物样品分析仪上的传送平台,包括可移动的承载板和位于承载板上并且可与承载板分离的载物台;载物台和承载板各自包括上表面和下表面,载物台的下表面与承载板的上表面彼此面对;载物台的上表面设有固定检测元件的限位结构,载物台和承载板上分别设有磁块,两者的磁块以磁性相吸方式排列;当载物台被放置在承载板上预先设定的区域内时,载物台和承载板上磁性相吸的磁块彼此靠近,使载物台自动移动到承载板上的指定位置。
进一步的,本发明所述传送平台上的载物台还可包括本发明所述的限位结构。
本发明还提供一种生物样品分析仪,其包括运动机构、光学检测机构和由运动机构驱动的本发明中所述的生物样品分析仪用的传送平台。
有益效果:
本发明的载物台结构能实现可以在不动载物台的前提下,特别是不翻转载物台的前提下,既可以承载试纸条实施检测,又可以承载检测板实施检测。同时,载物台上限位结构为凸台时,当选用试纸条检测的时候,凸台起到支撑和限位试纸条的作用;当选用检测板检测的时候,凸台起到检测板的定位作用,因凸台不均匀排布,可以起到限位作用和防呆作用,防止检测板放反。此外,在试纸条检测时载物台的凹槽除了能够容纳和限位检测板,还有很大的盛尿液空间,可以有效的减少尿液的污染。
同时,具有该载物台和检测单元的生物样品分析仪,体积变小;在检测过程中,避免了反复翻转载物台,减少操作步骤;同时,该载物台可拆卸搭载在电机带动的齿条板上,方便进出生物样品分析仪,拆卸方便,从而方便清洗。
本发明用于分析仢的传送平台由于采用呈异性相吸排列的磁铁,并且还设有定位结构,因此,操作时只需要把装有检测试剂的载物台放到承载板的预先设定的大致位置(无需精准定位),在磁力作用的驱动和定位结构的精确导引下,载物台就能自动到达承载板上的精准位置,实现自动精准定位,从而达到盲放的技术效果。因此,本发明具有操作简便、省时省力、工作效率高等优点。同时,本发明结构简单,成本低廉,适合广泛推广。
附图说明
图1为本发明的生物样品分析仪用的载物台的结构示意图。
图2为本发明的生物样品分析仪用的载物台的俯视图。
图3为本发明的生物样品分析仪用的载物台上放置检测板的示意图。
图4为图3的A-A剖视图。
图5为检测板的背面示意图。
图6为本发明的生物样品分析仪用的载物台上放置试纸条的示意图。
图7为图6的A-A剖视图。
图8为生物样品分析仪的检测单元的示意图。
图9为生物样品分析仪的检测单元上放置检测板的示意图。
图10为生物样品分析仪的检测单元上放置试纸条的示意图。
图11为载物台和承载板配合的分解示意图。
图12为包含另一载物台的生物样品分析仪的检测单元的示意图。
图13为与图12载物台配套的检测板示意图。
图14为包含另一载物台的生物样品分析仪的检测单元的示意图。
图15为本发明第一实施例中的承载板的立体示意图,显示出了承载板的上表面结构。
图16与图15相似,但是显示了磁块位于精确定位位置。
图17为承载板与载物台结合后的俯视图。
图18为图17沿A—A线的剖视图。
图18A为图18在位置A的局部放大示意图。
图18B为图18在位置B的局部放大示意图。
图19为本发明第二实施例中的载物台的立体示意图,显示出了载物台的下表面结构。
图19A为图19在位置A的局部放大示意图。
图19B为图19在位置B的局部放大示意图。
图20为本发明第二实施例中的承载板的立体示意图,显示出了承载板的上表面结构(包括了磁块)。
图20A为图20在位置A的局部放大示意图。
图20B为图20在位置B的局部放大示意图。
图21为图19与图20结合后的侧视局部剖视图,载物台到达承载板上精确定位位置。
图21A为图21在位置A的局部放大示意图。
图22为载物台与承载板上的磁块的极性第一种排列方案示意图。
图23为载物台与承载板上的磁块的极性第二种排列方案示意图。
图24为本发明第三实施例中的承载板的立体示意图,显示出了承载板的上表面结构(无磁块)。
图24A为图24沿线A-A方向的局部剖视放大示意图。
图25为本发明第四实施例中的承载板的立体示意图,显示出了承载板的上表面结构(无磁块)。
图26为本发明第四实施例中的载物台被放置到承载板的初始位置时的侧面剖视图。
图26A为图26在位置A的局部放大示意图。
图27与图26相似,但显示出了承载板上的精确定位位置。
图27A为图27在位置A的局部放大示意图。
图28为本发明第五实施例中的承载板的立体示意图,显示出了承载板的上表面结构(无磁块)。
图28A为图28在位置A的局部放大示意图。
图28B为图28在位置B的局部放大示意图。
图29与图28相似,但是包含了磁块。
图30为图29的平面俯视图。
图31为本发明第六实施例中的承载板的立体示意图,显示出了承载板的上表面结构(无磁块)。
图32为本发明第六实施例中的载物台的立体示意图,显示出了载物台的下表面结构(含磁块)。
图33是图31与图32结合后的初始位置的俯视图(局部剖视)。
图34与图33相似,但是显示了载物台到达承载板上精确定位位置。
图35是图34的侧面剖视图。
图36是本发明第七实施例中的承载板的立体示意图,显示出了承载板的上表面结构(无磁块)。
图37为本发明第七实施例中的载物台的立体示意图,显示出了载物台的下表面结构(无磁块)。
图38为图37与图38结合后的俯视图。
图39是图38沿A—A线的剖视图,显示了载物台与承载板结合后的初始位置。
图40与图39相似,但是显示了载物台与承载板结合后的精确定位位置。
附图标记
载物台100、100’、100”,磁块101、101’、401、401’,凹槽110,凸台111,载物台凹孔111’,凸条112,第一卡槽120,开口121,凸块122,第二卡槽130,卡槽凸钉134’,开口131,凸块132,凸起133,载物台下表面151,载物台上表面152,检测板200、200’,底板210,盖板220,凹孔211,检测板凸起211’,凹陷230,试纸条300、300’,基板301,检测试纸302,试纸条孔301’,检测单元10,承载板400,承载板上表面410,承载板下表面411,凹陷区412、413,竖墙416、153,沉孔414、414’,斜坡通道415,凸起154,凹槽417,圆锥体倒角引导孔418,排液渠419、419’,排液口420,第一磁孔102、402,第二磁孔102’、402’,龙门支架500,电机600,齿轮700,六角头900,检测光电PCB板800。
具体实施方式
在以下的详细描述中,图例附带的参考文字是这里的一个部分,它以举例说明本发明可能实行的特定具体方案的方式来说明。我们并不排除本发明还可以实行其它的具体方案和在不违背本发明的使用范围的情况下改变本发明的结构。
如图1-14所示,本发明用于生物样品分析仪的载物台,能够在同一面上既放置检测板,又放置检测试纸条(检测试纸条简称试纸条。为方便起见,将检测板和检测试纸条合称为检测元件)。操作者根据测试项目的需要,分别选择检测板或试纸条,并将检测板或试纸条放在载物台上,完成检测板和试纸条上的信息检测和分析,避免频繁从生物样品分析仪中取出或翻转载物台,从而在可以提高检测效率的同时,有效避免操作人员因操作繁琐而导致操作出错。因此,在载物台承载试纸条的同一面,比如正面,设有检测板限位结构。这个检测板限位结构使检测板被限定在载物台的合适位置,从而使载物台进入生物样品分析仪后,检测板上的检测结果正好位于光源检测区。
一些实施例中,检测板限位结构是与检测板配合的凸台,或者是与检测板配合的凹孔,或者是容纳检测板的凹槽,或者凸台与凹槽的结合,或者凹孔与凹槽的结合。
如图1至10所示的实施例中,载物台100上设有凸台111。该凸台111作为检测板限位结构,当载物台上放置检测板200时,凸台作为限位结构与检测板配合用于限位检测板200,起到将检测板定位在载物台的检测位置。同时,当试纸条位于载物台上时,该凸台111还对试纸条在载物台上的位置进行限位,能够保证检测板和试纸条上的检测结果正好位于生物样品分析仪的合适的光源检测区域,保证检测板和试纸条上的检测结果能够被生物样品分析仪准确读取。并且,凸台还作为支撑结构与试纸条配合,用于支撑试纸条300,使载物台上的试纸条处于一个基本相同的平面上。
在一个进一步优化的设计方案中,凸台在载物台上的高度设计为能够保证位于凸台上的试纸条检测高度和位于凸台上的检测板内的试纸条检测高度相同。这样,无论是检测板还是试纸条位于凸台上进行检测时,都能够位于生物样品分析仪的合适的光源检测区域,保证检测板和试纸条的检测结果被准确读取。
如图5所示实施例中的检测板200,包括底板210和盖板220。检测用的试纸条被安装在底板210上,盖板220盖合底板210和试纸条,形成检测板200。检测板的底板210背面设有与凸台111对应的凹孔211,该凹孔为检测板上的限位结构。在一个优化的设计中,检测板上的凹孔211的大小和位置均一一对应载物台上的凸台11。检测板200位于载物台100上后,凹孔211卡合在载物台上的凸台111内。
凸台111的个数没有限制,只要能实现与检测板的凹孔配合使得检测板能放置在载物台的正确的检测位。所述凸台111可以为一个,也可以为多个。具体的,凸台111的个数为1-5个;一个具体的实施例中,凸台111为3个。检测板凹孔211的数量可以与载物台上的凸台111相同或不同。凹孔211的数量与凸台111的数量相同,比如,当凸台111的数量为三个,凹孔211的数量也为三个。凹孔211的数量与凸台111的数量不同时,比如,当凸台111的数量为三个, 凹孔211的数量也为四个,其中三个凹孔与凸台对应,剩余的一个凹孔可以作为其他用途或在与该载物台配合时是闲置的。
载物台上的凸台可以均匀分布排列。在另一个优化的方案中,通过凸台111的不均匀排布,来识别和限定检测板200位于载物台100上的方向,保证检测板200放置在载物台100上的方向不会错误。避免检测板200方向放反或检测板偏离生物样品分析仪的光源检测区而导致的检测结果不准确或无法检测。凸台111在载物台100上为不均匀排布的实例中,具体的方式包括但不限于:凸台111不排列在同一条直线上;或者,凸台111之间的间距不相同。比如,当凸台111为两个时,两个凸台的中心连线不与检测板的横向中轴线或竖向中轴线平行;再比如,当凸条111为三个及以上时,相邻两凸台111之间的间距不相同;或者三个及以上的凸台111不设置在一条直线上。
凹孔211在检测板底板210背面的排布方式与凸台111在载物台100上的排布方式相同。比如,当凸台111为直线排列并间距不同时,与之对应,凹孔211排列在一条直线上并间距不同,并且凹孔211间距与凸台111间距一一对应相同。当凸台111位于载物台100中心线上时,凹孔211则排列在底板210的中心线上。
凹孔211在底板210背面可以穿透或不穿透整个底板210。当载物台上的凸台与检测板上的凹孔配合组装在一起时,凸台不会影响到检测板内试纸条的检测。
图1-10所示的实施例中,载物台100存放检测板的区域设有凹槽110,载物台的凹槽110用于容纳并限位检测板,一些实施例中,凸台111在凹槽110内。即凸台与凹槽相结合对检测板进行限位。此外,由于凹槽形成了很大的盛尿液空间,可以容纳试纸条300或检测板200溢出的尿液。一方面,收集在凹槽内的尿液不会流出载物台而对环境造成污染,另一方面,由于凹槽底部与放在凸台上的试纸条或检测板具有一定的距离,收集在凹槽底部的溢出尿液无法接触到试纸条或检测板,从而避免不同尿液样本污染了正在检测的试纸条或检测板。在进一步优化的设计中,在凹槽110两侧壁设有突出于侧壁的凸条112;凸条112的位置邻近凹槽110的端部;两侧壁的凸条112之间的间距等于检测板200宽度。通过两侧壁的凸条112与检测板200侧壁接触卡合使检测板200被更好的固定在凹槽110内。凹槽110的两个端部附近的两侧壁上均设有一个或多个凸条112。分列于凹槽110两侧壁的凸条112位置相对称。
为了更方便检测板200在载物台100上的拿取,特别是从凹槽中拿取,在检测板的底板210和盖板220两个侧壁中间位置处设凹陷部230,比如对称设计的凹陷部230。当从凹槽中取出检测板时,凹陷部形成的空间能方便操作者的手指或机械臂的抓夹伸入到所述凹陷部而抓取检测板。
如图12-13所示的实施例中,载物台上检测板限位结构为凹孔111’,其设置和排布方式参照前述凸台111的设置和排布。相应的,检测板200’底板的背面上设有与载物台凹孔111’配合的检测板凸起211’,该检测板凸起211’的数量和排布方式均与载物台凹孔111’一一对应,当检测板200’位于载物台100’上时,检测板200’上的检测板凸起211’一一对应插入载物台100’上的载物台凹孔111’内,使检测板200’被限定在载物台100’上。
所述限位结构凸台或凹孔,其截面可以是不同的形状。例如当凸台为3个时,其中两个凸台可以是正方形,第三个凸台的形状为圆形。相对应的,与之配合的检测板上的凹孔也分别为正方形和圆形。
如图8所示实施例中的试纸条300,包括基板301,在基板上粘贴有检测试纸302。所述检测试纸可以是尿联检测试纸、侧向横流(lateral flow)检测试纸等。
载物台上设有试纸条定位结构。例如,载物台上定位试纸条定位结构为卡槽或凸钉。当试纸条定位结构为凸钉时,与之配套,试纸条上设有试纸条孔。试纸条被卡槽卡合定位,或者试纸条孔与载物台上的凸钉配合使试纸条被定位。
如图1-10所示的实施例中,载物台100上的试纸条定位结构为卡槽,卡槽有两个,第一卡槽120和第二卡槽130,对应于试纸条的两端。第一卡槽120和第二卡槽130分别设置在凹槽 110的两端,对试纸条300进行定位和支撑。一些具体结构中,第一卡槽120位于载物台100的一个端部,方便从载物台100端部将试纸条300插入载物台100中。当液体样品添加到整个细长型的试纸条300后,液体的重量会导致试纸条中部下弯,当易下弯的中部获得凸台的支撑后,从而确保了在检测位时整个试纸条处于几乎相同的平面。因此,为了保证对试纸条300的更好的支撑,凸台111中心与第一卡槽120中心以及第二卡槽130中心位于同一直线上。也即,当试纸条300位于载物台100上时,试纸条300的两端分别位于第一卡槽120和第二卡槽130内的同时,凸台111位于试纸条300正下方。凹槽110的区域放置检测板200,卡槽120和130放置试纸条的两端,由于检测板200厚度大于试纸条300,因此在一个优选的设计中,凹槽110的深度大于第一卡槽120和第二卡槽130的深度,这样,当试纸条和检测板放入载物台上后,试纸条和检测板上的检测结果区域可以位于同一高度,并位于合适的光源区。更为具体的实施例中,为了保证试纸条位于同一水平高度,凹槽110中凸台111的高度与第一卡槽120和第二卡槽130比凹槽110高出的高度相同;或者,凹槽110与卡槽120和130深度相同,方便制作时一体成型,同时在第一卡槽120和第二卡槽130内均设有凸块122和132,凸块122和132高度与凹槽内的凸台111高度相同,这样保证位于卡槽和凹槽内的试纸条300位于水平状态。第一卡槽120和第二卡槽130宽度与试纸条300宽度相同,这样,卡槽能够更好的卡合定位试纸条。或者,第一卡槽120两端设有开口121;开口121宽度与试纸条300宽度相同。即通过第一卡槽的开口121处卡合试纸条300侧壁来使第一卡槽120与试纸条300的一端固定。同时,第二卡槽130一端开口131;开口131处设有对称的凸起133。以及,第二卡槽130末端两侧壁设有对称的凸起133。第二卡槽开口131处凸起133和侧壁凸起133之间的间距与试纸条300宽度相同。通过开口处的凸起133以及侧壁的凸起133与试纸条300侧壁接触来使试纸条的另一端被固定在第二卡槽130内。
如图12-13的实施例中,在载物台100’与凹孔的同一面上设有的试纸条定位结构为凸钉314’,该凸钉314’与载物台凹孔111’位于一条直线上。同时,在试纸条300’上设有试纸条孔301’。当试纸条300’位于载物台100’上后,试纸条孔301’套接在凸钉314’上,使试纸条300’被定位。当然,该试纸条定位结构也可以还包括第一卡槽120和第二卡槽130,凸钉314’位于第一卡槽120和第二卡槽130内,通过第一卡槽120和第二卡槽130与凸钉314’配合一起定位试纸条300’。当然,试纸条定位结构也可以是卡槽120、130与凸钉314’的结合,使试纸条300’被固定更为牢固。
如图14的实施例中,载物台100”上的限位结构为凸台111,与之对应的检测板200的限位结构式凹孔211。而载物台100”上的试纸条定位结构为凸钉314’,与之对应的试纸条300’定位结构为试纸条孔301’。
检测板和试纸条又可称为检测装置,检测板限位结构和试纸条定位结构又可称为检测装置固定结构。
一种用于生物样品分析的生物样品分析仪,包括载物台和检测单元。所述载物台100用于生物样品分析仪中,具体的,载物台100用于置于生物样品分析仪的检测单元10中,将检测板200或试纸条300带入检测单元10中,通过检测单元10对检测板200或试纸条300的信息读取和分析反馈,来实现生物样品分析仪的检测分析功能,如图8-14所示。
具体的,如图1-14所示,检测单元10包括载物台、载物台运送平台、运动机构和光学检测机构。更具体的,检测单元10包括载物台100或100’或100”、运送平台包括承载板400,运动机构包括电机600和齿轮700,光学检测机构包括光源(例如六角头900)和检测光电PCB板800。所述六角头是一个光路检测通道,周围一圈分布着6个LED灯,中间是PD接收通道,它与检测光电PCB板装配,然后再安装到龙门支架上。电机600与齿轮700连接,齿轮700与承载板400齿轮啮合,同时,齿轮700和六角头900以及检测光电PCB板800都连接在龙门支架500上,电机600带动齿轮700转动,齿轮700通过齿轮啮合带动承载板400在龙门支架500上直线往复运动,最终带动位于承载板400上的载物台100在龙门支架500内直线进出;从而 实现载物台100进入龙门支架500,六角头900和检测光电PCB板800配合读取位于载物台100上的检测板200或试纸条300上的信息;以及,实现载物台100离开龙门支架500,能够实现更换载物台100上检测板200或试纸条300,以及取下载物台100进行清洗的功能。
载物台100置于承载板400上,如图8至11所示的实例中,载物台100可拆卸式地固定在承载板400上。一个具体的实施例中,图11所示,承载板400与载物台100通过磁块吸力配合,实现承载板和载物台可拆卸式的组装。具体的,载物台背面的两端设有磁孔,分别是第一磁孔102和第二磁孔102’;在承载板上的两端设有磁孔,分别是第一磁孔401和第二磁孔402’。在第一磁孔102中装入磁块101,在第二磁孔102’中装入磁块101’,同样的,在磁孔402中也压入磁块(图中未示出磁块)。并且,载物台上第一磁孔102和第二磁孔102’内的两个磁块101,101’面向承载板这面的磁性相反,比如,第一磁孔102内的磁块101面向承载板的一面是S极,则第二磁孔102’内的磁块101’面向承载板一面是N极。并且在承载板400的磁孔402内各压入一个磁块的磁性与所述磁块的磁性与载物台背面的磁块磁面相吸,即与载物台第一磁孔102相对应的承载板第一磁孔401内压入磁块,所述磁块面向载物台的一面是N极,与载物台第二磁孔102’相对应的承载板第二磁孔402’内压入磁块,所述磁块面向载物台的一面的磁块是S极。根据磁性的同性相斥,异性相吸的原理,载物台放在承载板上只能是102对应402,以及102’对应402’放置,这样磁孔内的磁块是相互吸引的。如果错误地将102对应402’、102’对应402,磁孔内的磁块相互排斥的,载物台无法放在承载板上。这样可以保证载物台在承载板上的方向不会放置错误。
下面就本发明的图8-10的实施例的检测单元10来进行操作描述。
本实施例的检测板200以HCG检测板为例,检测板内放置的是用于检测HCG的试纸。本实施例中的试纸条300为尿常规检测的尿联检测试纸为例,例如尿11联、尿12联检测试纸等。
当操作者需要对尿样中的HCG进行检测时,通过电机600控制,载物台100在承载板400的带动下,移动出龙门支架500,在载物台的凹槽110内安置检测板200,使检测板200的凹孔211和凹槽内的凸台111一一对应卡合,并向检测板的加样孔中添加尿样。然后,在驱动承载板400带动载物台100运动到龙门支架500下后,六角头900和检测光电PCB板800对检测板200上的检测信息进行读取和分析。待检测完毕后,电机600驱动承载板400带动载物台100运动离开龙门支架500,取下检测板200。若紧接着要采用尿联试纸进行尿常规检测时,载物台100在承载板400的带动下,移动出龙门支架500,在载物台的第一卡槽120和第二卡槽130内安置试纸条300,使试纸条300被卡合在第一卡槽120和第二卡槽130内,同时让试纸条300的中部位于凸台111上获得支撑。然后,在驱动承载板400带动载物台100运动到龙门支架500下后,六角头900和检测光电PCB板800对试纸条300上的检测信息进行读取和分析。当检测完毕后,电机600驱动承载板400带动载物台100运动离开龙门支架500,取下试纸条300。本发明所述的载物台既可以放尿联的试纸条进行测试,也可以放HCG板进行测试。在尿联试纸和检测板的转换过程中,并不需要移动载物台。
当完成所有检测时,电机600带动载物台100运动至龙门支架500下收纳。当需要对载物台100进行清洗时,通过电机600将承载板400和载物台100运动移出龙门支架500,将载物台100从承载板400上取下进行清洗,清洗完成后,再通过磁吸将载物台的磁块101与承载板的磁块401对应吸附连接在一起。再通过电机600将承载板400和载物台100运动移入龙门支架500。
请参阅图1-40所示,本发明还提供了一种用于分析仪的传送平台,包括可移动的承载板400和载物台100。承载板400由电机600和齿轮700等驱动,可作往复运动。载物台100被放置在承载板400上,并且可与承载板400分离。承载板400之面向载物台100的那一面为其上表面410,相反面为下表面411。载物台100之面对承载板400的那一面为下表面151,相反面为上表面152(图19)。载物台100和承载板400上分别设有磁性相吸的磁块101、401。当载物台100被放置在承载板400上预先设定的区域内时,磁块101、401的吸力使载物台100自动 移动到承载板400上的指定位置,从而实现载物台100相对承载板400自动定位。
请参阅图15-18B所示,这是本发明之第一实施例。承载板400的上表面410在靠近承载板上的磁块401、401’的区域,优选在承载板上放置两块磁块401、401’的正上方位置处,分别设有凹陷区412、413(图18A、图18B所示)。凹陷区412、413的轮廓为矩形、正方形、圆形或者椭圆形(图15和图16中只显示了矩形,其他形状省略),其面积大于载物台100内的磁块101的外轮廓。因此,当将载物台100放置到承载板400上时,只需要将载物台100内的磁块101、101’分别放置在承载板400之上表面410的凹陷区412、413内(即预先设置的区域),载物台100内的磁块101、101’在承载板400之上表面410的凹陷区412、413内尚有可活动的空间,而无需放在精准定位位置,在磁块的吸力作用下,载物台100和承载板400内的磁块尽量相互靠近,从而带动载物台100和承载板400自动精准定位,进而达到了盲放的技术效果。由于凹陷区412、413的轮廓为矩形、正方形、圆形或者椭圆形,其面积大于载物台100内的磁块101、101’的外轮廓,因此,很容易就可以将载物台上的磁块101、101’分别放置到凹陷区412、413内,所以操作非常方便。
为了定位更加精准,本发明用于分析仪的传送平台包括两对彼此间隔适当距离的磁块101、101’(分别沿载物台100和承载板400之纵长方向排布,为简便起见,下文只详细描述其中一对磁块结构和定位方式,另一对磁块可以类推)。载物台100上的两个磁块101、101’在同一方向(例如垂直向下方向)的极性相反;承载板400上的两个磁块401、401’在同一方向(例如垂直向下方向)的极性也相反;因此,载物台100上的磁块和承载板400上对应的磁块呈异性相吸排布(排列方式如下)。
Figure PCTCN2021080953-appb-000001
图22、23显示载物台和承载板上的磁块磁性的两种排列方案(该排列方案适用于全部实施例)。
请参阅图19-21A所示,这是本发明之第二实施例。本实施例与第一实施例的区别在于:承载板400的上表面410和载物台100的下表面151分别设有相互配合的定位结构。在本实施例中,定位结构包括分别设置在承载板之上表面410和载物台之下表面151的竖墙416、153。当把载物台100放置到承载板上预先设置的区域后,磁块101的吸力使竖墙416、153相互抵靠,从而实现自动定位。请参阅图21A所示,承载板400和载物台100上的磁块的轴线不是重合的,而是偏移了距离F,介于0.5-3.0毫米之间,因此,磁块101、401相互吸引,促使竖墙416、153持续保持抵靠。如此设计,可以确保载物台100在承载板400上更加精确地定位。
请参阅图24、24A所示,这是本发明之第三实施例。本实施例与第一实施例的区别在于:将承载板上表面410上的凹陷区412、413分别替换成轮廓尺寸与凸出于载物台下表面151的磁块101的外形尺寸对应的两个沉孔414、414’(如图24所示)。换言之,承载板之上表面410在其两个磁块401、401’的正上方设有与固定在载物台上的两个磁块101、101’的外形相适应的沉孔414、414’(图24A仅以一对磁块101’、401’的位置关系为例进行说明,另一对磁块101、401的位置关系可参照获得)。即,载物台上的磁块101’至少部分凸出于载物台的下表面151,并且可以至少部分进入沉孔414’内,但又尽量限制载物台上的磁块101’在沉孔414’内在与载物台上表面410平行的方向上晃动。载物台上之磁块101’为圆柱体,承载板上的沉孔414’的轮廓也是圆柱体,沉孔414’的直径比磁块101’的直径大0.1-1.0毫米。为了方便引导磁块101’更加容易地沿垂直于承载板上表面410的方向进入沉孔414’,在本实施例的一种方案中,沉孔414’的最上端开口处设有尺寸更大的圆锥体倒角引导孔418。在优选的方案中,倒角的深度L为0.3-2.0毫米,倒角与沉孔垂直轴线的夹角a介于30度到60度之间(优选40 度)。需要说明的是,在本实施例的其他方案中,沉孔414、414’的最上端开口处也可以不包括圆锥体倒角引导孔418。
请参阅图25-27A所示,这是本发明之第四实施例。本实施例与第三实施例的区别在于:承载板之上表面410设有一段与沉孔414连通的斜坡通道415,斜坡通道415从离沉孔414较远位置处向离沉孔414较近位置处逐渐下降(另一边对应的斜坡通道415’,结构相似,不再赘述)。当载物台100被放置到承载板400上的预先设定的位置时(图26A所示),在磁块的吸力作用下,载物台100上的磁块沿着斜坡通道415、415’大致在承载板400的纵长方向分别滑入到沉孔414、414’,及至磁块抵靠沉孔414、414’的侧壁,从而实现精确定位(图27A所示)。
请参阅图28-30所示,这是本发明之第五实施例。本实施例结合了第一实施例和第三实施例的结构,即同时包括了凹陷区412和沉孔414的设计,沉孔414位于凹陷区412内。当载物台100被放置到承载板400上的预先设定的位置时(磁块101被放置在凹陷区412内),在磁块的吸力作用下,载物台100上的磁块自动滑入到沉孔414内,抵靠沉孔414的侧壁,从而实现精确定位(如图29、30所示)。
请参阅图28A和图28B所示,以实施例五为例,承载板上表面410在靠近承载板上的磁块401、401’的区域,分别设有与沉孔414、414’相连通的排液渠419、419’,以便将泄漏到此处的液体(例如尿液)及时排出。更进一步地,排液渠419还包括排液孔420。在一种设计中,排液孔420的底比排液渠419的底要低,但是并不贯穿至承载板下表面411。在另一种设计中,排液孔420贯穿至承载板下表面411。另外,也可以在沉孔414、414’的底部安置吸水性材料,将泄漏到此处的液体吸收掉。还可以在排液渠419和\或排液孔420内安置吸水性材料,将泄漏到此处的液体吸收掉。这些吸水性材料选自于:吸水性滤纸、海绵、硝化纤维膜和玻璃纤维膜。
另请参阅图15、图16、图18A和图20B。排液渠419、排液孔420的设计不仅适用于实施例五,也适用于其他的实施例。例如,在实施例一、二、六、七中,承载板上表面410设有与凹陷区连通的排液孔420,所述排液孔420贯穿或者不贯穿至承载板下表面411。在实施例三、四中,承载板上表面410设有与沉孔414、414’连通的排液渠419,排液渠419包括排液孔420,排液孔420贯穿或者不贯穿至承载板下表面411。
请参阅图31-35所示,这是本发明之第六实施例。本实施例与前述实施例的区别在于:定位结构不同。在本实施例中,定位结构包括分别设置在承载板上表面410上和载物台下表面151的相互配合的凸起154和凹槽417,凸起154落入凹槽417内,磁块的吸力使凸起154和凹槽417的侧壁相互抵靠,从而实现自动定位。在本实施例中,承载板400和载物台100上的凸起154和凹槽417在承载板之上表面410或者载物台之下表面151上的正投影的外轮廓为楔形。当载物台100被放置到承载板400上的预先设定的位置时(凸起154被放置在和凹槽417内),在磁块的吸力作用下,凸起154在凹槽417内沿承载板400之纵长方向(图33所示的X方向)滑动,及至凸起154和凹槽417的侧壁相互抵靠,从而实现精确定位(如图34、35所示)。虽然图中显示凸起154被设计在载物台100上,凹槽417被设计在承载板400上,但是,也可以将凸起154设计在承载板400上,将凹槽417设计在载物台100上。
请参阅图36-40所示,这是本发明之第七实施例。本实施例与第六实施例的区别在于:承载板和载物台上的凸起154’和凹槽417’在承载板或者载物台之横截面的轮廓为上宽下窄的楔形或者倒梯形。当载物台100被放置在承载板400上预先设定的位置时,在磁块的吸力作用下,凸起154’在大致垂直于承载板之上表面410的方向滑入凹槽417’内,从而引导当载物台100自动到达承载板400上的精准定位位置。虽然图中显示凸起154’被设计在载物台100上,凹槽417’被设计在承载板400上,但是,也可以将凸起154’设计在承载板400上,将凹槽417’设计在载物台100上。
以上的描述仅为本发明的具体实施方式,并非因此限制本发明所要求保护的范围。凡是利用本发明说明书及附图内容所作的等效结构或等效流程变换,或直接或间接运用在其它相关的技术领域,均同理包括在本发明的保护范围内。

Claims (15)

  1. 一种生物样品分析仪用的传送平台,其特征在于:包括可移动的承载板和载物台,载物台被放置在承载板上并且可与承载板分离;承载板之面向载物台的那一面为上表面,相反面为下表面;载物台之面对承载板的那一面为下表面,相反面为上表面;载物台和承载板上分别设有磁性相吸的磁块,当载物台被放置在承载板上预先设定的区域内时,磁块的吸力使载物台相对承载板自动定位。
  2. 根据权利要求1所述的传送平台,其特征在于:包括两对彼此间隔适当距离的磁块,载物台上的两个磁块在同一方向的极性相反,承载板上的两个磁块在同一方向的极性相反,载物台上的磁块和承载板上对应的磁块呈异性相吸排布。
  3. 根据权利要求2所述的传送平台,其特征在于:承载板之上表面在靠近磁块的区域设有凹陷区;当载物台上的磁块进入该凹陷区时,磁块的吸力使载物台相对承载板自动定位。
  4. 根据权利要求1、2或者3之一所述的传送平台,其特征在于:承载板的上表面和载物台的下表面分别设有相互配合的定位结构。
  5. 根据权利要求1、2或者3之一所述的用于分析仪的传送平台,其特征在于:载物台上的磁块至少部分凸出于载物台的下表面,承载板在其上表面设有沉孔,载物台上凸出的磁块落入承载板上的沉孔,并且抵靠沉孔的孔壁,从而实现自动定位。
  6. 根据权利要求5所述的传送平台,其特征在于:承载板之上表面设有一段与沉孔连通的斜坡通道,斜坡通道从离沉孔较远位置处向离沉孔较近位置处逐渐下降。
  7. 根据权利要求4所述的传送平台,其特征在于:定位结构包括分别设置在承载板之上表面和载物台之下表面的凸起,磁块的吸力使这些凸起相互抵靠,从而实现自动定位。
  8. 根据权利要求4所述的传送平台,其特征在于:定位结构包括分别设置在承载板之上表面和载物台之下表面的相互配合的凸起和凹槽,凸起落入凹槽内,磁块的吸力使凸起和凹槽的侧壁相互抵靠,从而实现自动定位。
  9. 根据权利要求8所述的传送平台,其特征在于:承载板和载物台上的凸起和凹槽在承载板之上表面或者载物台之下表面上的正投影的外轮廓为楔形。
  10. 根据权利要求8所述的传送平台,其特征在于:承载板和载物台上的凸起和凹槽在承载板或者载物台之横截面的轮廓为上宽下窄的楔形或者倒梯形。
  11. 根据权利要求1或者2之一所述的用于分析仪的传送平台,其特征在于:承载板上表面在靠近承载板上之磁块的区域设有排液渠。
  12. 根据权利要求3所述的用于分析仪的传送平台,其特征在于:承载板上表面设有与凹陷区连通的排液孔,所述排液孔贯穿至承载板下表面。
  13. 根据权利要求5所述的传送平台,其特征在于:承载板上表面设有与沉孔连通的排液渠,所述排液渠包括贯穿至承载板下表面的排液孔。
  14. 根据权利要求1、2或者3之一所述的传送平台,其特征在于:其特征在于,所述载物台上还包括限位结构。
  15. 一种生物样品分析仪,包括权利要求1至14之一所述的传送平台。
PCT/CN2021/080953 2020-01-16 2021-03-16 生物样品分析仪用的载物台、传送平台和生物样品分析仪 WO2021143953A1 (zh)

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