WO2021075839A1 - Lentille intraoculaire multifocale ayant des zones de plage vision de près asymétriques - Google Patents

Lentille intraoculaire multifocale ayant des zones de plage vision de près asymétriques Download PDF

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Publication number
WO2021075839A1
WO2021075839A1 PCT/KR2020/013975 KR2020013975W WO2021075839A1 WO 2021075839 A1 WO2021075839 A1 WO 2021075839A1 KR 2020013975 W KR2020013975 W KR 2020013975W WO 2021075839 A1 WO2021075839 A1 WO 2021075839A1
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WO
WIPO (PCT)
Prior art keywords
range
intraocular lens
backing
field
multifocal intraocular
Prior art date
Application number
PCT/KR2020/013975
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English (en)
Korean (ko)
Inventor
엄영섭
Original Assignee
고려대학교 산학협력단
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Application filed by 고려대학교 산학협력단 filed Critical 고려대학교 산학협력단
Publication of WO2021075839A1 publication Critical patent/WO2021075839A1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1627Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing index of refraction, e.g. by external means or by tilting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1616Pseudo-accommodative, e.g. multifocal or enabling monovision
    • A61F2/1618Multifocal lenses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2002/1681Intraocular lenses having supporting structure for lens, e.g. haptics

Definitions

  • the present invention relates to a multifocal intraocular lens having an asymmetrical near-field, and more specifically, to minimize light loss during cataract surgery.
  • the present invention relates to a multifocal intraocular lens having an asymmetrical near/medium distance area capable of improving both near, intermediate and far vision while minimizing visual impairment such as bleeding.
  • the lens is a place in the eye that acts as a lens for a camera. It refracts light to form a clear image on the retina. As shown in FIG. 1, cataract is a disease in which vision is deteriorated because opacity occurs in the lens due to various reasons and thus transparency is lost.
  • Cataract surgery is a surgery in which the lens of a patient with turbidity is removed, and an artificial lens to replace the lens is inserted in its place.
  • the intraocular lens inserted into the eye during cataract surgery can be divided into a single focal lens with one focal point and a multifocal intraocular lens with multiple foci.
  • Short-focus IOLs are inserted by selecting to focus on a specific distance between far and near, and after surgery, you need to wear myopia glasses to see the far distance clearly or wear a magnifying glass to see the near distance clearly.
  • Multifocal IOLs can be divided into diffractive multifocal IOLs and refractive multifocal IOLs according to the method of changing the path of light to have multiple focal points.
  • the diffractive multifocal intraocular lens has been reported to lose 10 to 16% of light due to diffraction, and this loss of light causes several diffraction rings, halos, and light bleeding around the light, especially at night, causing visual impairment. I can make it.
  • the refractive multifocal IOL can be expected to reduce light spreading and glare by minimizing light loss due to the nature of refraction.
  • a multifocal intraocular lens having an asymmetrical near-field area capable of minimizing light loss during cataract surgery has a far-field and a near-field and mid-range in the area excluding the far-field.
  • a lens unit having at least one or more of the distance areas; And a support portion protruding in a direction staggered from each other along the circumferential direction of the lens unit, wherein each of the short-range region and the intermediate-distance region includes a plurality of first asymmetrical shapes of a closed cross-section in a radial direction with respect to the distant region. At least one or more refraction power and second refraction power are formed.
  • the first additional refractive power in the near region may be formed with the same refractive power or may be formed with different refractive powers.
  • the first backing refractive power when the first backing refractive power is formed with the same refractive power, the first backing refractive power may be formed by any one of 1.50 diopters(D), 1.75 D, 2.00 D, 2.25 D, 2.50 D, 2.75D and 3.00 D.
  • the first backing power and the second backing power are formed with different refractive powers
  • the first backing power is 1.75 D, 2.00 D, 2.25 D, 2.50 D, 2.75D, and 3.00 D.
  • the additional refractive power may be formed by any one of 0.75D, 1.00D, 1.25D, and 1.50D.
  • the boundary between the distant region, the near region, and the intermediate distance region may be formed with a continuous refractive change so as to minimize light loss and light spread.
  • the multifocal intraocular lens having an asymmetrical near-field uses an artificial intraocular lens having a near-field of multiple asymmetrical refraction powers to minimize light loss during cataract surgery, thereby reducing visual impairment such as haze and light bleeding after cataract surgery. As it can be minimized, it not only improves the quality of vision, but also improves vision in both distance, medium, and near distances, thereby increasing the satisfaction of vision.
  • 1 is a diagram showing a conceptual comparison between a normal lens and a cataract lens.
  • FIG. 2 is a schematic diagram of a multifocal intraocular lens having an asymmetric near-field and far-field region according to an embodiment of the present invention.
  • FIG. 3 is a schematic diagram of a multifocal intraocular lens having an asymmetrical near-field, intermediate-range, and far-field according to a second embodiment of the present invention.
  • FIG. 4 is a view showing various embodiments of a multifocal intraocular lens having an asymmetrical near-field according to an embodiment of the present invention.
  • 5 is an experimental result of a simulation according to a distance of a multifocal intraocular lens having an asymmetrical near-field according to the prior art and an embodiment of the present invention.
  • FIG. 2 is a schematic diagram of a multifocal intraocular lens having an asymmetrical near-field according to an embodiment of the present invention
  • FIG. 3 is a multifocal having an asymmetrical near-field, intermediate-range, and far-field according to the second embodiment of the present invention.
  • It is a schematic diagram of an artificial lens
  • FIG. 4 is a view showing various embodiments of a multifocal intraocular lens having an asymmetrical near-field according to an embodiment of the present invention.
  • a multifocal intraocular lens having an asymmetrical near-field is capable of minimizing light loss during cataract surgery, and the lens unit 110 and the support unit 120 ).
  • the lens unit 110 includes a near-field 111, an intermediate-range 113, and a far-field 112.
  • Each of the short-distance region 111 and the intermediate-distance region 113 may be formed of at least one or more so as to have an asymmetric first backing power and a second backing refractive power instead of a ring shape of a closed cross-section.
  • asymmetry means that, as shown in Figs. 2 to 4, the arc shape is continuous and does not form a ring shape, and is cut off at least once in the middle to form asymmetry for other regions except for a specific direction. do.
  • the near-field region 111 and the intermediate-distance region 113 are in regions excluding a specific direction (y-axis) It means to form an asymmetry.
  • the first additional refractive power of the near-field 111 may be formed with the same refractive power or different refractive powers.
  • the first backing refractive power may be formed of any one of 1.50 diopters(D), 1.75 D, 2.00 D, 2.25 D, 2.50 D, 2.75D and 3.00 D.
  • the first backing power and the second backing power are formed with different backing powers
  • the first backing power is 1.75 D, 2.00 D, 2.25 D, 2.50 D, 2.75D, and 3.00 D
  • the second backing refractive power may be formed of any one of 0.75D, 1.00D, 1.25D, and 1.50D.
  • first backing power and second backing power are examples, and may be variously changed as necessary.
  • the boundary between the far area 112 and the near area 111 minimizes light loss and light spread through continuous refraction changes. I can make it.
  • the boundary between the distant region 112, the near region 111, and the intermediate region 113 is It is desirable to be formed with continuous refractive change so as to be minimized.
  • the support part 120 may be formed to protrude in a direction staggered from each other along the circumferential direction of the lens part.
  • 5 is an experimental result of a simulation according to a distance of a multifocal intraocular lens having an asymmetrical near-field according to the prior art and an embodiment of the present invention.
  • Comparative Example 1 is a short focal intraocular lens
  • Comparative Example 2 is an artificial lens having a distant and a near region
  • an embodiment of the present invention has a near, intermediate, and distant triple focus. It is an artificial lens.
  • the multifocal intraocular lens according to the present invention may be manufactured for intracapsular fixation into which an artificial intraocular lens is inserted during conventional cataract surgery.
  • it is manufactured in the form of being inserted into the ciliary sulcus, so that it can serve as a multifocal artificial crystalline lens alone as an intraocular lens inserted into the ciliary sulcus.
  • it can act as a multifocal intraocular lens together with the intracystic monofocal intraocular lens inserted into the ciliary sulcus in addition to the existing intracystic monofocal intraocular lens.
  • the multifocal intraocular lens having an asymmetrical near-field uses an artificial intraocular lens having a near-field of several asymmetrical refraction powers to minimize light loss during cataract surgery, thereby reducing visual impairment such as halos and light bleeding after cataract surgery. As it can be minimized, it not only improves the quality of vision, but also improves vision in both distance, medium, and near distances, thereby increasing the satisfaction of vision.

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

La présente invention concerne une lentille intraoculaire multifocale ayant des zones de plage vision de près asymétriques, apte à réduire au minimum une perte de lumière dans une chirurgie de la cataracte, la lentille intraoculaire multifocale comprenant : une partie de lentille ayant une zone de plage vision de loin, et une zone de plage vision de près et/ou une zone de plage vision intermédiaire dans une zone qui exclut la zone de plage vision de loin ; et une partie de support faisant saillie dans des directions croisées le long de la direction circonférentielle de la partie de lentille, au moins l'une de la zone de plage vision de près et de la zone de plage intermédiaire étant formée avec une pluralité de premières sous-réfractions et de secondes sous-réfractions selon une forme asymétrique au lieu d'une forme d'anneau fermé dans la direction radiale par rapport à la zone de plage vision de loin. Selon la présente invention, des lentilles intraoculaires ayant plusieurs zones de plage vision de près de sous-réfractions asymétriques sont utilisées de façon à réduire au minimum une perte de lumière dans une chirurgie de la cataracte, de telle sorte que des perturbations visuelles telles que l'irisopsie et la réduction de la lumière peuvent être réduites au minimum après la chirurgie de la cataracte, ce qui permet d'améliorer la qualité de la vision et de la vision pour l'ensemble de la vision de près, de la plage intermédiaire et de la vision de loin, et ainsi la satisfaction de la vision peut être améliorée.
PCT/KR2020/013975 2019-10-14 2020-10-14 Lentille intraoculaire multifocale ayant des zones de plage vision de près asymétriques WO2021075839A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020190126601A KR102339078B1 (ko) 2019-10-14 2019-10-14 비대칭 근거리 영역을 가지는 다초점 인공수정체
KR10-2019-0126601 2019-10-14

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WO2021075839A1 true WO2021075839A1 (fr) 2021-04-22

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PCT/KR2020/013975 WO2021075839A1 (fr) 2019-10-14 2020-10-14 Lentille intraoculaire multifocale ayant des zones de plage vision de près asymétriques

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921496A (en) * 1987-08-24 1990-05-01 Grendahl Dennis T Radially segemented zone of focus artificial hydrogel lens
KR940013470A (ko) * 1992-12-09 1994-07-15 죠엘 알, 페트로우 안과용 렌즈 및 다중초점 시력 교정 제공 방법
US20050128432A1 (en) * 2003-12-16 2005-06-16 Altmann Griffith E. Multifocal contact lens and method of manufacture thereof
KR20110132381A (ko) * 2009-02-17 2011-12-07 오큘런티스 비.브이. 광학 섹터를 갖는 안과용 렌즈
KR101248488B1 (ko) * 2004-12-01 2013-04-02 알콘, 인코퍼레이티드 애포다이즈드 비구면 회절 렌즈

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7381221B2 (en) * 2002-11-08 2008-06-03 Advanced Medical Optics, Inc. Multi-zonal monofocal intraocular lens for correcting optical aberrations
US6951391B2 (en) * 2003-06-16 2005-10-04 Apollo Optical Systems Llc Bifocal multiorder diffractive lenses for vision correction
US7481532B2 (en) * 2006-02-09 2009-01-27 Alcon, Inc. Pseudo-accommodative IOL having multiple diffractive patterns
EP2928414B1 (fr) 2012-12-06 2017-08-23 Novartis AG Modèle de bord pour réduire les effets photiques dans des lentilles intraoculaires

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921496A (en) * 1987-08-24 1990-05-01 Grendahl Dennis T Radially segemented zone of focus artificial hydrogel lens
KR940013470A (ko) * 1992-12-09 1994-07-15 죠엘 알, 페트로우 안과용 렌즈 및 다중초점 시력 교정 제공 방법
US20050128432A1 (en) * 2003-12-16 2005-06-16 Altmann Griffith E. Multifocal contact lens and method of manufacture thereof
KR101248488B1 (ko) * 2004-12-01 2013-04-02 알콘, 인코퍼레이티드 애포다이즈드 비구면 회절 렌즈
KR20110132381A (ko) * 2009-02-17 2011-12-07 오큘런티스 비.브이. 광학 섹터를 갖는 안과용 렌즈

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KR102339078B1 (ko) 2021-12-14
KR20210043815A (ko) 2021-04-22

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