WO2020263190A1 - Xanthones permettant de diminuer la production de lipides dans les sébocytes - Google Patents

Xanthones permettant de diminuer la production de lipides dans les sébocytes Download PDF

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Publication number
WO2020263190A1
WO2020263190A1 PCT/SG2020/050367 SG2020050367W WO2020263190A1 WO 2020263190 A1 WO2020263190 A1 WO 2020263190A1 SG 2020050367 W SG2020050367 W SG 2020050367W WO 2020263190 A1 WO2020263190 A1 WO 2020263190A1
Authority
WO
WIPO (PCT)
Prior art keywords
skin
compound
composition
group
sebocytes
Prior art date
Application number
PCT/SG2020/050367
Other languages
English (en)
Inventor
Jun Xi Selwyn LOW
Xinhong LIM
Maurice VAN STEENSEL
Kai Xuan Keith TAN
Original Assignee
Agency For Science, Technology And Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency For Science, Technology And Research filed Critical Agency For Science, Technology And Research
Publication of WO2020263190A1 publication Critical patent/WO2020263190A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des composés xanthones destinés à être utilisés dans un procédé de diminution de la production de lipides dans les sébocytes ; des compositions comprenant au moins un tel composé ; l'utilisation d'une telle composition pour diminuer la production de lipides dans les sébocytes ; et une méthode cosmétique permettant de diminuer la production de lipides dans les sébocytes. Dans certains modes de réalisation, le composé est choisi dans le groupe constitué par l'α-mangostine et la γ-mangostine.
PCT/SG2020/050367 2019-06-25 2020-06-25 Xanthones permettant de diminuer la production de lipides dans les sébocytes WO2020263190A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201905849X 2019-06-25
SG10201905849X 2019-06-25

Publications (1)

Publication Number Publication Date
WO2020263190A1 true WO2020263190A1 (fr) 2020-12-30

Family

ID=74062100

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SG2020/050367 WO2020263190A1 (fr) 2019-06-25 2020-06-25 Xanthones permettant de diminuer la production de lipides dans les sébocytes

Country Status (1)

Country Link
WO (1) WO2020263190A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023238058A1 (fr) * 2022-06-07 2023-12-14 Dyson Operations PTE. LTD. Compositions d'acide oléanolique pour la régulation du sébum

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107638377A (zh) * 2017-10-31 2018-01-30 广州赛莱拉干细胞科技股份有限公司 一种含山竹干细胞提取物的控油美白护肤品及其制备方法
CN107789253A (zh) * 2017-10-31 2018-03-13 广州赛莱拉干细胞科技股份有限公司 一种祛痘补水护肤品及其制备方法
KR101987717B1 (ko) * 2017-12-05 2019-06-11 주식회사 코리아나화장품 크리소파놀, 망기페린 및 시코노퓨란 a를 포함하는 여드름 완화 및 피지분비 억제용 화장료 조성물

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107638377A (zh) * 2017-10-31 2018-01-30 广州赛莱拉干细胞科技股份有限公司 一种含山竹干细胞提取物的控油美白护肤品及其制备方法
CN107789253A (zh) * 2017-10-31 2018-03-13 广州赛莱拉干细胞科技股份有限公司 一种祛痘补水护肤品及其制备方法
KR101987717B1 (ko) * 2017-12-05 2019-06-11 주식회사 코리아나화장품 크리소파놀, 망기페린 및 시코노퓨란 a를 포함하는 여드름 완화 및 피지분비 억제용 화장료 조성물

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
PAN-IN PORNTIP; WONGSOMBOON ATTHAKORN; KOKPOL CHAYADA; CHAICHANAWONGSAROJ NUNTAREE; WANICHWECHARUNGRUANG SUPASON: "Depositing a-mangostin nanoparticles to sebaceous gland area for acne treatment", JOURNAL OF PHARMACOLOGICAL SCIENCES, vol. 129, no. 4, 1 December 2015 (2015-12-01), pages 226 - 232, XP055778965, ISSN: 1347-8613, DOI: 10.1016/J.JPHS. 2015.11.00 5 *
SUKATTA UDOMLAK; TAKENAKA MAKIKO; ONO HIROSHI; OKADOME HIROSHI; SOTOME ITARU; NANAYAMA KAZUKO; THANAPASE WARUNEE; ISOBE SEIICHIRO: "Distribution of Major Xanthones in the Pericarp, Aril, and Yellow Gum of Mangosteen (Garcinia Mangostana Linn.) Fruit and Their Contribution to Antioxidative Activity", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, vol. 77, no. 5, 23 May 2014 (2014-05-23), pages 984 - 987, XP055778971, ISSN: 0916-8451, DOI: 10.1271/BBB.120931 *
XU NUO, DENG WENJUAN, HE GAIYING, GAN XIAOSHUANG, GAO SHUANG, CHEN YU, GAO YITIAN, XU KE, QI JUNMEI, LIN HAOJIE, SHEN LI, LI XIAOK: "Alpha- and gamma-mangostins exhibit anti-acne activities via multiple mechanisms", IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, vol. 40, no. 5, 13 November 2018 (2018-11-13), pages 415 - 422, XP009525904, DOI: 10.1080/08923973.2018.1519831 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023238058A1 (fr) * 2022-06-07 2023-12-14 Dyson Operations PTE. LTD. Compositions d'acide oléanolique pour la régulation du sébum

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