WO2020250182A3 - 지페노사이드 화합물을 유효성분으로 포함하는 퇴행성 신경질환 치료용 조성물 - Google Patents

지페노사이드 화합물을 유효성분으로 포함하는 퇴행성 신경질환 치료용 조성물 Download PDF

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WO2020250182A3
WO2020250182A3 PCT/IB2020/055510 IB2020055510W WO2020250182A3 WO 2020250182 A3 WO2020250182 A3 WO 2020250182A3 IB 2020055510 W IB2020055510 W IB 2020055510W WO 2020250182 A3 WO2020250182 A3 WO 2020250182A3
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composition
neurodegenerative disease
gypenoside
compound
active ingredient
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PCT/IB2020/055510
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English (en)
French (fr)
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WO2020250182A2 (ko
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정병수
도은경
김홍기
이근우
송우석
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주식회사 모든바이오
정병수
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Publication of WO2020250182A2 publication Critical patent/WO2020250182A2/ko
Publication of WO2020250182A3 publication Critical patent/WO2020250182A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 지페노사이드 화합물 또는 이의 약학적으로 허용되는 염을 유효성분으로 포함하는 퇴행성 신경질환의 예방, 개선 또는 치료용 조성물에 관한 것으로, 상기 조성물은 퇴행성 신경질환에 따른 학습능력 및 기억력 감퇴를 억제하는 효과가 우수하여 상기 질환의 예방, 개선 또는 치료에 유용하게 사용될 수 있다.
PCT/IB2020/055510 2019-06-13 2020-06-12 지페노사이드 화합물을 유효성분으로 포함하는 퇴행성 신경질환 치료용 조성물 WO2020250182A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020190070208A KR102059659B1 (ko) 2019-06-13 2019-06-13 지페노사이드 화합물을 유효성분으로 포함하는 퇴행성 신경질환 치료용 조성물
KR10-2019-0070208 2019-06-13

Publications (2)

Publication Number Publication Date
WO2020250182A2 WO2020250182A2 (ko) 2020-12-17
WO2020250182A3 true WO2020250182A3 (ko) 2021-05-06

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PCT/IB2020/055510 WO2020250182A2 (ko) 2019-06-13 2020-06-12 지페노사이드 화합물을 유효성분으로 포함하는 퇴행성 신경질환 치료용 조성물

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KR (1) KR102059659B1 (ko)
WO (1) WO2020250182A2 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102059659B1 (ko) * 2019-06-13 2019-12-26 주식회사 모든바이오 지페노사이드 화합물을 유효성분으로 포함하는 퇴행성 신경질환 치료용 조성물
KR102534935B1 (ko) * 2020-12-02 2023-05-22 한양대학교 에리카산학협력단 진세노사이드를 유효성분으로 포함하는 알츠하이머 예방 또는 치료용 약학적 조성물

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103933052A (zh) * 2014-01-04 2014-07-23 中国医学科学院药用植物研究所 七叶胆苷ⅹⅶ在制备用于防治心脑血管及神经退行性疾病药物中的应用
KR20170042139A (ko) * 2015-10-08 2017-04-18 충북대학교 산학협력단 돌외 추출물 또는 지페노시드를 유효성분으로 포함하는 파킨슨병에서 나타나는 기억력 장애의 치료 또는 예방용 조성물
KR101928553B1 (ko) * 2018-08-07 2018-12-12 주식회사 모든바이오 진세노사이드 화합물을 함유하는 인플라마좀 매개 염증성 질환의 예방 또는 치료용 조성물
KR102059659B1 (ko) * 2019-06-13 2019-12-26 주식회사 모든바이오 지페노사이드 화합물을 유효성분으로 포함하는 퇴행성 신경질환 치료용 조성물

Patent Citations (4)

* Cited by examiner, † Cited by third party
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CN103933052A (zh) * 2014-01-04 2014-07-23 中国医学科学院药用植物研究所 七叶胆苷ⅹⅶ在制备用于防治心脑血管及神经退行性疾病药物中的应用
KR20170042139A (ko) * 2015-10-08 2017-04-18 충북대학교 산학협력단 돌외 추출물 또는 지페노시드를 유효성분으로 포함하는 파킨슨병에서 나타나는 기억력 장애의 치료 또는 예방용 조성물
KR101928553B1 (ko) * 2018-08-07 2018-12-12 주식회사 모든바이오 진세노사이드 화합물을 함유하는 인플라마좀 매개 염증성 질환의 예방 또는 치료용 조성물
KR102059659B1 (ko) * 2019-06-13 2019-12-26 주식회사 모든바이오 지페노사이드 화합물을 유효성분으로 포함하는 퇴행성 신경질환 치료용 조성물

Non-Patent Citations (2)

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Title
CAI HUI, LIANG QIANLEI, GE GUANQUN: "Gypenoside Attenuates β Amyloid-Induced Inflammation in N9 Microglial Cells via SOCS1 Signaling", NEURAL PLASTICITY, HINDAWI, vol. 2016, 1 January 2016 (2016-01-01), pages 1 - 10, XP055808337, ISSN: 2090-5904, DOI: 10.1155/2016/6362707 *
LEE BOMBI, SHIM INSOP, LEE HYEJUNG: "Gypenosides Attenuate Lipopolysaccharide-Induced Neuroinflammation and Memory Impairment in Rats", EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, OXFORD UNIVERSITY PRESS, US, vol. 2018, 19 June 2018 (2018-06-19), US, pages 1 - 10, XP055808338, ISSN: 1741-427X, DOI: 10.1155/2018/4183670 *

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KR102059659B1 (ko) 2019-12-26

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