WO2020242331A3 - Coincidence detection system for measuring arterial blood time-activity curves and methods of using same - Google Patents

Coincidence detection system for measuring arterial blood time-activity curves and methods of using same Download PDF

Info

Publication number
WO2020242331A3
WO2020242331A3 PCT/QA2020/050007 QA2020050007W WO2020242331A3 WO 2020242331 A3 WO2020242331 A3 WO 2020242331A3 QA 2020050007 W QA2020050007 W QA 2020050007W WO 2020242331 A3 WO2020242331 A3 WO 2020242331A3
Authority
WO
WIPO (PCT)
Prior art keywords
btac
invasive
methods
detection system
same
Prior art date
Application number
PCT/QA2020/050007
Other languages
French (fr)
Other versions
WO2020242331A2 (en
Inventor
Jim William O'DOHERTY
Othmane BOUHALI
Yassine TOUFIQUE
Original Assignee
Qatar Foundation For Education, Science And Community Development
Sidra Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qatar Foundation For Education, Science And Community Development, Sidra Medicine filed Critical Qatar Foundation For Education, Science And Community Development
Publication of WO2020242331A2 publication Critical patent/WO2020242331A2/en
Publication of WO2020242331A3 publication Critical patent/WO2020242331A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computerised tomographs
    • A61B6/037—Emission tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4266—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a plurality of detector units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/504—Clinical applications involving diagnosis of blood vessels, e.g. by angiography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/58—Testing, adjusting or calibrating apparatus or devices for radiation diagnosis
    • A61B6/582—Calibration
    • A61B6/583—Calibration using calibration phantoms

Abstract

The present disclosure describes a method for calculating measurements of the blood time activity curve (BTAC) for use with positron emission tomography (PET), using a small field of view coincidence detector system. The disclosed method of using a non-invasive in vivo arterial sampling system, which in combination with the use of computational stimulations, successfully calculates a blood-time activity curve (BTAC) within individual subjects. The BTAC can be used in the application of kinetic models without physical arterial sampling or reliance on image-based techniques. This method allows a non-invasive measurement of the same variable as that determined by invasive measurements, and leads to higher subject compliance.
PCT/QA2020/050007 2019-05-31 2020-05-30 Coincidence detection system for measuring arterial blood time-activity curves and methods of using same WO2020242331A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962855338P 2019-05-31 2019-05-31
US62/855,338 2019-05-31
US201962870315P 2019-07-03 2019-07-03
US62/870,315 2019-07-03
US202063002845P 2020-03-31 2020-03-31
US63/002,845 2020-03-31

Publications (2)

Publication Number Publication Date
WO2020242331A2 WO2020242331A2 (en) 2020-12-03
WO2020242331A3 true WO2020242331A3 (en) 2021-03-25

Family

ID=73552090

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/QA2020/050007 WO2020242331A2 (en) 2019-05-31 2020-05-30 Coincidence detection system for measuring arterial blood time-activity curves and methods of using same

Country Status (1)

Country Link
WO (1) WO2020242331A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114152635A (en) * 2021-10-15 2022-03-08 中国人民解放军军事科学院军事医学研究院 Equivalent simulation device for neutron energy spectrum in human blood vessel after neutron external irradiation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090108206A1 (en) * 2007-10-29 2009-04-30 Siemens Medical Solutions Usa, Inc. MR-Compatible Blood Sampling System For PET Imaging Applications in Combined PET/MR Imaging System
US20090218502A1 (en) * 2006-02-17 2009-09-03 Jan Axelsson Beta-radiation detector for blood flow and chromatography
US20100128956A1 (en) * 2007-04-17 2010-05-27 National Institute Of Radiological Sciences Pet scanner and image reconstruction method thereof
US20120112078A1 (en) * 2010-03-31 2012-05-10 Millett John MOBILE CARDIAC POSITRON EMISSION TOMOGRAPHY (moPET) CAMERA
US20180271470A1 (en) * 2017-03-23 2018-09-27 Wisconsin Alumni Research Foundation Methods for quantifying pancreatic beta cell function and mass properties with radiomanganese positron emission tomography

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090218502A1 (en) * 2006-02-17 2009-09-03 Jan Axelsson Beta-radiation detector for blood flow and chromatography
US20100128956A1 (en) * 2007-04-17 2010-05-27 National Institute Of Radiological Sciences Pet scanner and image reconstruction method thereof
US20090108206A1 (en) * 2007-10-29 2009-04-30 Siemens Medical Solutions Usa, Inc. MR-Compatible Blood Sampling System For PET Imaging Applications in Combined PET/MR Imaging System
US20120112078A1 (en) * 2010-03-31 2012-05-10 Millett John MOBILE CARDIAC POSITRON EMISSION TOMOGRAPHY (moPET) CAMERA
US20180271470A1 (en) * 2017-03-23 2018-09-27 Wisconsin Alumni Research Foundation Methods for quantifying pancreatic beta cell function and mass properties with radiomanganese positron emission tomography

Also Published As

Publication number Publication date
WO2020242331A2 (en) 2020-12-03

Similar Documents

Publication Publication Date Title
Dey et al. InstaBP: cuff-less blood pressure monitoring on smartphone using single PPG sensor
Hemon et al. Comparison of foot finding methods for deriving instantaneous pulse rates from photoplethysmographic signals
JP2016528981A5 (en)
RU2016107845A (en) MONITORING SYSTEM AND METHOD FOR MONITORING HEMODYNAMIC STATUS OF SUBJECT
MX2020005042A (en) System for monitoring patients suffering from respiratory disease comprising a portable medical device and method based on the use of such system.
Hamacher et al. Towards the assessment of local dynamic stability of level-grounded walking in an older population
RU2016142360A (en) DEVICE FOR PROCESSING AND METHOD FOR PROCESSING DATA ON THE HEART ACTIVITY OF A LIVING BEING
Rajala et al. Pulse arrival time (PAT) measurement based on arm ECG and finger PPG signals-comparison of PPG feature detection methods for PAT calculation
JP2018500982A5 (en)
JP2016534770A5 (en)
BR112015022173A2 (en) apparatus and methods for computing cardiac output of a living individual by applanation tonometry
Panagiota et al. Assessment of human gait speed and energy expenditure using a single triaxial accelerometer
WO2011159972A3 (en) Detection of noise during heart beat variation evaluation
Altini et al. Estimating running performance combining non-invasive physiological measurements and training patterns in free-living
WO2017055670A1 (en) Method and apparatus for estimating the transit time of the aortic pulse from time intervals measured between fiducial points of a ballistocardiogram
MX2020002223A (en) Compressive imaging method and system.
WO2017100519A1 (en) Systems and methods for adaptable presentation of sensor data
RU2019129106A (en) SYSTEM AND METHOD FOR UNSIGNIFICANT DETERMINATION OF FERTILIZER WINDOWS
WO2020242331A3 (en) Coincidence detection system for measuring arterial blood time-activity curves and methods of using same
Rasool et al. Continuous and noninvasive blood pressure estimation by two-sensor measurement of pulse transit time
JP2020531109A5 (en)
US20180199833A1 (en) Device for calculating systolic blood pressure using pulse transit time and method therefor
JP2016506278A5 (en)
KR101576666B1 (en) System and method for cardiopulmonary fitness estimation in daily life
Jang et al. A Gaussian model-based probabilistic approach for pulse transit time estimation

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20813420

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 20813420

Country of ref document: EP

Kind code of ref document: A2