WO2020238601A1

WO2020238601A1 - Acquisition assembly and acquisition device

Info

Publication number: WO2020238601A1
Application number: PCT/CN2020/089673
Authority: WO
Inventors: 李剑; 李亚青; 李明锐; 孟星宇; 吴汉玲; 蔡云
Original assignee: 深圳微伴生物有限公司
Priority date: 2019-05-30
Filing date: 2020-05-11
Publication date: 2020-12-03

Abstract

An acquisition assembly and an acquisition device, which can solve the problems in the prior art of low acquisition efficiency and easy spilling of a preservation liquid. The acquisition assembly comprises: an acquisition member (10) provided with a communication structure, the acquisition member (10) being used for acquiring a sample; and a uniform-mixing member (20) having a uniform-mixing chamber and a preservation liquid chamber (21) which are provided independently of each other, the uniform-mixing chamber being used for uniformly mixing the sample and a preservation liquid, and the preservation liquid chamber (21) being used for storing the preservation liquid; the acquisition member (10) has a retreat position and a communication position relative to the uniform-mixing member (20), when the acquisition member (10) is in the retreat position, the preservation liquid chamber (21) is in a sealed state, and when the acquisition member (10) is in the communication position, the communication structure can enable the communication between the preservation liquid chamber (21) and the uniform-mixing chamber, so as to allow the preservation liquid in the preservation liquid chamber (21) to enter the uniform-mixing chamber.

Description

Collection component and collection device

This application claims the priority of the patent application filed to the State Intellectual Property Office of China on May 30, 2019, the application number is 201910464782.7, and the invention title is "collection piece and collection device", and it is filed on September 19, 2019 Priority to the patent application of the State Intellectual Property Office of China, the application number is 201910888000.2, and the invention title is "collection components and collection devices".

Technical field

The present application relates to the technical field of collection devices, and in particular to a collection component and a collection device.

Background technique

At present, stool detection is a routine clinical laboratory test item. In the stool detection process, it is necessary to use a collection spoon or a collection stick to sample the stool.

In the prior art, after the collection spoon or collection rod is used to complete the feces sampling, the collection spoon or collection rod with the stool sample needs to be put into the mixing tube, and then the preservation solution is injected into the mixing tube, and the mixing tube is used to Mix the sample with the preservation solution, and then use the mixed solution for testing.

However, in the prior art, due to the many collection steps, the collection efficiency is low, and the existing method of injecting the preservation solution into the mixing tube easily causes the preservation solution to spill.

Summary of the invention

The present application provides a collection assembly and a collection device to solve the problems of low collection efficiency and easy spillage of preservation liquid in the prior art.

According to one aspect of the present application, there is provided a collection assembly, which includes: a collection part provided with a conducting structure, and the collection part is used for collecting samples; and the mixing part has a mixing cavity and a storage liquid cavity that are independently arranged , The mixing chamber is used to mix the sample and the preservation solution, and the preservation liquid chamber is used to store the preservation solution; among them, the collection piece has an avoiding position and a conduction position relative to the mixing piece. When the collection piece is in the avoiding position, the preservation liquid cavity It is in a sealed state; when the collecting piece is in the conducting position, the conducting structure can conduct the storage liquid cavity with the mixing cavity, so as to conduct the storage liquid in the storage liquid cavity into the mixing cavity.

Further, the mixing member includes a mixing tube and a preservation liquid tube connected to each other, the preservation liquid tube has a preservation liquid cavity, and the mixing tube has a mixing cavity.

Further, the preservation liquid pipe has a double wall structure, the preservation liquid pipe has an inner layer and an outer layer which are arranged oppositely, and there is a gap between the inner layer and the outer layer, and the gap forms a preservation liquid cavity.

Further, the preservation liquid chamber has a first end and a second end which are arranged oppositely, the first end of the preservation liquid chamber is arranged close to the collecting member, the first end of the preservation liquid chamber is a closed structure, and the second end of the preservation liquid chamber is an opening Structure, the preservation liquid cavity can be communicated with the mixing cavity through the opening structure.

Further, the mixing element further includes: a plugging component, which is arranged at the opening structure, the plugging component is used to close the storage liquid cavity, and the plugging component has a blocked state and an open state. When the collecting piece moves from the avoiding position to the conductive In the position, the conducting structure cooperates with the blocking component to switch the blocking component from the blocking state to the open state.

Further, the plugging assembly includes: a sealing element arranged at the second end of the preservation liquid chamber; a connecting element arranged at the second end of the preservation liquid chamber; the sealing element seals the opening structure through the connecting element, and the connecting element has a second end arranged oppositely. The sealing position and the first open position, and the conduction structure is used to drive the connecting member to move from the first closed position to the first open position. When the connecting member is in the first open position, the storage liquid chamber communicates with the mixing chamber.

Further, the connecting piece is clamped on the inner layer, the sealing piece has a ring structure, the outer edge of the sealing piece is connected with the end surface of the outer layer, and the inner edge of the sealing piece is connected with the end surface of the inner layer through the connecting piece.

Further, the mixing tube includes a first section and a second section that are connected to each other. The first section of the mixing tube is arranged close to the collecting part, and the cross-sectional size of the first section of the mixing tube is larger than that of the second section of the mixing tube. Cross-sectional size, the preservation solution tube is located in the first section of the mixing tube.

Further, the collection piece includes: a body with a holding end and a collection end that are arranged oppositely, the conducting structure is arranged on the body, and the collection end is provided with a collection hole; the solid collection part is arranged at the collection end, and the solid collection part is used for collection. Solid sample; a suction and discharge part, which is arranged on the holding end and communicates with the collection hole, and the suction and discharge part sucks or discharges the liquid sample through the collection hole.

Further, a conductive sheet is provided on the side wall of the main body, and the extending direction of the conductive sheet is the same as the axial direction of the main body, and the conductive sheet forms a conductive structure.

Further, the collecting piece further includes a collecting head cover, one end of the collecting head cover and the mixing piece is detachably connected, the collecting head cover is provided with an escape hole, and the suction and draining piece partially penetrates the avoiding hole.

Further, the solid collection part includes a plurality of convex walls, the plurality of convex walls are arranged at intervals along the circumferential direction of the collection end, and a sample collection area is formed between two adjacent convex walls.

Further, a through hole is provided on the surface of at least one convex wall, and the through hole communicates with the sample collection area; and/or the convex wall has a free end and a connecting end that are oppositely arranged, and the connecting end of the convex wall is connected to the side wall of the collection end , The thickness of the free end is less than the thickness of the connecting end; and/or the convex wall is bent in a direction away from the body, and the bending direction of each convex wall is the same.

Further, the solid collection part includes: a collection shell sleeved on the collection end, the collection shell has a collection cavity, and the surface of the collection shell is a porous structure.

Further, the collection shell has a spherical structure.

According to another aspect of the present application, a collection device is provided. The collection device includes: a collection component, the collection component being the collection component provided above; a filter component, which is detachably connected to the collection component, and the filter component is used to compare the sample with the preservation solution The mixed liquid is filtered.

Further, the filter assembly includes: a filter tube having a first end and a second end that are arranged oppositely; the first end of the filter tube is detachably connected with the mixing tube of the collection assembly; and the filter screen is arranged in the filter tube.

Further, the mixing piece of the collection assembly further includes a protective plug. The protective plug is set in the mixing tube and is located close to the outlet of the mixing tube. The protective plug has a second blocking position and a second open position that are relatively disposed. When the protective plug is in the second blocking position, the protective plug blocks the outlet of the mixing tube. The filter tube is provided with a boss, which corresponds to the protective plug. The position between the filter tube and the mixing tube is adjustable. The relative position between the tube and the mixing tube is to use the boss to drive the protective plug to move.

Further, the collection device further includes a collection tube, which is detachably connected to the filter assembly, and the collection tube is used to collect the liquid filtered by the filter assembly.

Applying the technical solution of the present application, the collection component includes a collection part and a mixing part. Wherein, the collecting piece is provided with a conducting structure, the collecting piece is used for collecting samples, and the collecting piece has an avoiding position and a conducting position relative to the mixing piece. By making the mixing member have a mixing cavity and a storage chamber that are set independently of each other, after the collection member is used to complete the sample collection, only the collection member needs to be moved to the conductive position, and the conductive structure on the collection member can be used to The storage solution chamber is connected to the mixing chamber, so that the storage solution in the storage solution chamber can flow into the mixing chamber, so that the sample and the storage solution can be mixed in the mixing chamber. The above device eliminates the need for staff Injecting the preservation solution into the mixing piece can simplify the collection steps, thereby improving the collection efficiency, and the preservation solution will not have the risk of spilling during the inflow process, ensuring the normal mixing of the sample.

Description of the drawings

The drawings of the specification forming a part of the application are used to provide a further understanding of the application, and the exemplary embodiments and descriptions of the application are used to explain the application, and do not constitute an improper limitation of the application. In the attached picture:

Figure 1 shows an exploded view of a collection component provided according to an embodiment of the present application;

Figure 2 shows an exploded view of a collection device according to another embodiment of the present application;

FIG. 3 shows a schematic diagram of the structure of the preservation liquid tube in FIG. 1;

Fig. 4 shows a schematic structural diagram of the filter tube in Fig. 2;

Fig. 5 shows another structural schematic diagram of the filter tube in Fig. 2;

Figure 6 shows a top view of the filter tube in Figure 2;

FIG. 7 shows a schematic diagram of the structure of the solid collecting part in FIG. 1;

Fig. 8 shows another schematic diagram of the structure of the solid collecting part in Fig. 1.

Among them, the above drawings include the following reference signs:

10. Collecting piece; 11. Body; 111, conductive sheet; 12. Solid collecting part; 121, convex wall; 121a, through hole; 121b, free end; 121c, connecting end; 13, suction and discharge piece; 14, collecting head Cover; 15, collection shell;

20. Mixing part; 21. Preservation liquid chamber; 22. Mixing tube; 23. Preservation tube; 231. Inner layer; 232. Outer layer; 24. Blocking component; 241. Seal; 242. Connecting part; 25. Protective plug; 26. Mixing tube cover; 27. Mixing beads;

30. Filter assembly; 31. Filter tube; 32. Filter mesh; 33. Boss; 40. Collection tube.

Detailed ways

The technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all of the embodiments. The following description of at least one exemplary embodiment is actually only illustrative, and in no way serves as any restriction on the application and its application or use. Based on the embodiments in this application, all other embodiments obtained by those of ordinary skill in the art without creative work fall within the protection scope of this application.

As shown in FIG. 1, an embodiment of the present application provides a collection component, which includes a collection part 10 and a mixing part 20. Wherein, the collecting piece 10 is provided with a conducting structure, and the collecting piece 10 is used for collecting samples. Specifically, the mixing member 20 has a mixing cavity and a preservation liquid cavity 21 that are independently arranged. The mixing cavity is used for mixing the sample and the preservation solution, and the preservation liquid cavity 21 is used for storing the preservation solution. Wherein, the collecting member 10 has a avoiding position and a conducting position relative to the mixing member 20. When the collecting member 10 is at the avoiding position, the storage liquid chamber 21 is in a sealed state, and the storage liquid will not spill from the storage liquid chamber 21; When the collecting member 10 is in the conducting position, the conducting structure can conduct the storage liquid chamber 21 and the mixing chamber, so as to conduct the storage liquid in the storage liquid chamber 21 into the mixing chamber. At this time, the sample can be mixed. Mix well with the preservation solution in the homogenizing cavity.

Specifically, the user can use the collection piece 10 to collect a stool sample. During the process of collecting the sample, the collection piece 10 is located in the avoiding position. At this time, the storage liquid chamber 21 is in a sealed state, and the storage liquid will not spill from the storage liquid chamber 21. The user will not come into contact with the preservation liquid, which can improve the safety of the device. After the user completes the sample collection by using the collecting piece 10, by moving the collecting piece 10 to the conducting position, the conducting structure on the collecting piece 10 can connect the storage liquid chamber 21 with the mixing chamber, and the storage liquid can be directly connected From the storage liquid chamber 21 into the storage liquid chamber 21 of the mixing member 20, the storage liquid will not spill out. With the above structure, it is only necessary to move the collecting piece 10 from the avoiding position to the conducting position, and the process of loading the collecting piece 10 into the mixing piece 20 and combining the preservation solution with the sample can be completed at the same time, which can simplify the collection steps and improve the collection. effectiveness.

Wherein, the storage liquid cavity 21 of the mixing member 20 may be integrally formed with the mixing member, or an independent part may be provided, and the storage liquid chamber 21 may be provided in the independent part. In this embodiment, the mixing member 20 has an independently arranged part, and a storage liquid chamber 21 is arranged in the part.

Using the collection assembly provided in this embodiment, by making the mixing member 20 have a mixing cavity and a storage liquid chamber 21 that are independently arranged, after the collection member 10 is used to complete the sample collection, it is only necessary to move the collection member 10 to conduction. Position, the conductive structure on the collection piece 10 can be used to connect the storage liquid chamber 21 with the mixing chamber, so that the storage liquid in the storage liquid chamber 21 can flow into the mixing chamber, so that the sample and the storage liquid can be The mixing is carried out in the mixing chamber. With the above device, the staff does not need to inject the preservation solution into the mixing part, which can simplify the collection steps, thereby improving the collection efficiency, and the preservation solution will not be spilled during the inflow process. , To ensure the normal mixing of samples.

In this embodiment, the mixing member 20 includes a mixing tube 22 and a preservation liquid tube 23 connected to each other. The preservation liquid tube 23 has a preservation liquid cavity 21 and the mixing tube 22 has a mixing cavity. Wherein, the preservation liquid tube 23 can be arranged at one end of the mixing tube 22, or the preservation liquid tube 23 can be directly arranged inside the mixing tube 22. In this embodiment, the preservation liquid tube 23 is arranged inside the mixing tube 22. Thus, after the preservation liquid chamber 21 is connected to the mixing chamber by the conductive structure on the collecting member 10, the preservation liquid chamber 21 is located in the mixing chamber. Inside the homogenizing cavity, the preservation liquid can directly enter the mixing cavity, thereby solving the problem of easy spillage of the preservation liquid.

In other embodiments, by means of integral molding, the storage liquid chamber 21 and the mixing chamber can be provided in the mixing tube 22 at the same time, so that the storage liquid tube 23 may not be separately provided, which can simplify the structure of the device and reduce the processing cost. .

As shown in FIG. 3, the preservation liquid pipe 23 has a double-walled structure. The preservation liquid pipe 23 has an inner layer 231 and an outer layer 232 oppositely arranged, and there is a gap between the inner layer 231 and the outer layer 232, which forms the preservation liquid Cavities 21. Specifically, the collection piece 10 can pass through the inner layer 231 into the mixing cavity of the mixing tube 22. With the above structure, the preservation liquid tube 23 can be used to store the preservation liquid, and the preservation liquid tube 23 will not block the collection piece 10. In this embodiment, the preservation liquid pipe 23 has an annular cylindrical structure. In other embodiments, the preservation liquid tube 23 may have a semi-annular column shape, a meniscus column shape or other structures.

In this embodiment, the preservation liquid chamber 21 has a first end and a second end that are arranged oppositely. Wherein, the first end of the preservation liquid chamber 21 is arranged close to the collecting member 10, and the first end of the preservation liquid chamber 21 is a closed structure, and the preservation liquid will not be spilled from the first end of the preservation liquid chamber 21. In addition, the second end of the preservation liquid chamber 21 has an open structure, and the preservation liquid chamber 21 can be communicated with the mixing chamber through the opening structure. Since the second end of the preservation liquid chamber 21 is disposed toward the inside of the mixing tube 22, it is convenient to store. The liquid flows from the preservation liquid chamber 21 into the mixing chamber.

Wherein, the mixing member 20 further includes a plugging component 24, the plugging component 24 is arranged at the opening structure of the storage liquid cavity 21, and the plugging component 24 is used for sealing the storage liquid cavity 21. Specifically, the blocking component 24 has a blocking state and an open state. When the collecting piece 10 moves from the avoiding position to the conducting position, the conducting structure cooperates with the blocking component 24 to switch the blocking component 24 from the blocking state to In the open state, the storage liquid chamber 21 is connected to the mixing chamber at this time. Among them, the blocking component 24 includes a seal, a valve, etc., as long as the blocking component 24 can block the opening structure and switch from the blocked state to the open state.

In this embodiment, the blocking component 24 includes a sealing member 241 and a connecting member 242. Wherein, the sealing member 241 and the connecting member 242 are both arranged at the second end of the storage liquid chamber 21, wherein the sealing member 241 seals the opening structure through the connecting member 242, and the shape of the sealing member 241 matches the opening structure of the storage liquid chamber 21, The connecting member 242 has a first blocking position and a first open position that are relatively set. When the collecting member 10 is in the avoiding position, the connecting member 242 is located in the first blocking position. At this time, the storage liquid chamber 21 is blocked by the sealing member 241. Closed structure. Specifically, the conductive structure is used to drive the connecting member 242 from the first blocking position to the first open position. When the collecting member 10 moves to the conductive position, the connecting member 242 is located in the first open position. At this time, the liquid chamber is stored. 21 is connected to the mixing cavity.

Specifically, the connecting member 242 is clamped on the inner layer 231, and the sealing member 241 has a ring structure. By connecting the outer edge of the sealing member 241 with the end surface of the outer layer 232, and connecting the inner edge of the sealing member 241 with the end surface of the inner layer 231 through the connecting member 242, the sealing member 241 can be fixed to the second end of the storage liquid chamber 21 , The storage liquid chamber 21 is sealed by the seal 241. In this embodiment, the sealing member 241 includes a sealing film, and a clamping boss is provided on the inner wall of the inner layer 231. During the process of assembling the connecting member 242 inside the inner layer 231, the clamping boss can restrict the connecting member 242. When the connecting piece 242 is assembled in place against the clamping boss, that is, the connecting piece 242 is at the first blocking position, and the end of the connecting piece 242 is flush with the end surface of the second end of the storage liquid chamber 21. The sealing film is fixed on the second end of the storage liquid chamber 21 to complete the sealing of the storage liquid chamber 21. When the conductive structure drives the connecting piece 242 to move from the first blocking position to the first open position, the connecting piece 242 is located at the first open position, and the storage liquid chamber 21 is in communication with the mixing chamber at this time. Wherein, the sealing member 241 includes a transparent film of a certain material or a film of other materials, and the sealing method can be heat-sealed or other methods according to the production process and usage requirements.

In this embodiment, the mixing tube 22 includes a first section and a second section that are connected to each other. The first section of the mixing tube 22 is disposed close to the collecting member 10, and the cross-sectional size of the first section of the mixing tube 22 is larger than that of the mixing tube. For the cross-sectional size of the second section of the homogenizing tube 22, the preservation liquid tube 23 is located in the first section of the mixing tube 22. With the above structure, the first section of the mixing tube 22 can be used to accommodate the preservation liquid tube 23, and the volume of the device can be reduced. In addition, after assembling the preservation liquid tube 23 into the first section of the mixing tube 22, the end of the preservation liquid tube 23 will abut the second section of the mixing tube 22, and the second section of the mixing tube 22 can be used. The storage liquid tube 23 is restricted in position to fix the storage liquid tube 23 to prevent the storage liquid tube 23 from excessively entering the mixing tube 22. Moreover, by making the cross-sectional size of the first section of the mixing tube 22 larger than the cross-sectional size of the second section of the mixing tube 22, on the one hand, it is convenient for the collection piece 10 contaminated with fecal samples to extend into the mixing tube 22 and avoid The stool sample hits the nozzle or the user's hand to enhance the user's collection experience; on the other hand, it is for placing the preservation liquid tube.

The collecting member 10 includes a main body 11, a solid collecting part 12 and a suction and discharge member 13. Wherein, the main body 11 has a holding end and a collection end that are arranged oppositely, the conductive structure is arranged on the main body 11, and the collection end is provided with a collection hole. By arranging the solid collecting part 12 at the collecting end, the solid collecting part 12 can be used to collect solid samples. By disposing the suction and discharging member 13 on the holding end and connecting the suction and discharge member 13 with the collection hole, the suction and discharge member 13 sucks or sucks through the collection hole. Discharge the liquid sample. With the above structure, the collection member 10 is suitable for both quantitative collection of solid feces and quantitative collection of liquid feces, thereby improving collection efficiency and meeting the needs of feces collection. By adjusting the size of the solid collection part 12 and the suction and discharge part 13, quantitative sampling can be achieved. In this embodiment, the suction and discharge member 13 includes a silicone suction tip. Specifically, the silica gel tip is a hollow cavity structure, the volume of the hollow cavity can be determined or adjusted by the volume to be sampled, and the solid collection part 12 is used to achieve quantitative collection of samples.

Among them, the quantitative collection piece can be the above-mentioned integrated dry and wet collection piece, and it can also be divided into dry and wet separation as two collection pieces for design. The size of the silica gel head can be adjusted according to the reagent demand, and it can be in the body according to the needs. Mark or print on the scale.

In the prior art, the Bristol stool classification method is a medical classification method for stool. According to the shape, stool is divided into 7 categories, namely: Type 1: Hard balls (difficult to pass); Type 2: Sausage-like, but with uneven surface; Type 3: Sausage-like, but with cracks on the surface; Type 4: Like a sausage or snake, and with a smooth surface; Type 5: Soft block with smooth edges ( Easy to pass); Type 6: thick fluffy lumps, mushy stool; Type 7: watery, without solid lumps (completely liquid).

In this embodiment, there is a hollow structure with a certain aperture in the center of the main body 11, which is used to collect the seventh type of water-like feces. The solid collection part 12 is a wheel-shaped fan blade structure in a clockwise direction on all sides. It is thinner, and the height of the solid collection part 12 and the width of the fan blade can realize the quantification of stool samples. The two wheel-shaped fan blades have parallel small holes in the structure, and the small holes are supplemented by the homogenization operation. In this embodiment, there is a 2 mm flow hole in the center of the main body 11.

In addition, the outer periphery of the fan blade is thin or sharp. This design plays an important role in whether the collection piece can collect fecal samples. The direction and angle of the fan blade opening, the number of fan blades, the opening of the fan blade, and the upper The shape, diameter, number of holes, height of the fan blades, etc. can be adjusted accordingly according to actual sampling requirements.

If samples of types 1-6 are collected, the sample fills the gap of the solid collection part 12, and the quantitative collection of the samples is completed; if the samples of type 7 are collected, the sample can be obtained by squeezing the silicone head with a certain space on the top Since the pressure difference enters the hollow structure of the body 11 through the solid collection part 12, quantitative collection of water-like samples is realized.

Specifically, a conductive sheet 111 is provided on the side wall of the main body 11, and the extending direction of the conductive sheet 111 is the same as the axial direction of the main body 11, and the conductive sheet 111 forms a conductive structure. By arranging the conducting piece 111 on the side wall of the main body 11, when the collecting piece 10 is moved to the conducting position during the process of extending the collecting piece 10 into the mixing tube 22, the conducting piece 111 will interact with the connecting piece 242. Abut and drive the connecting member 242 to move to the first open position, so that the storage liquid chamber 21 is in communication with the mixing chamber.

In this embodiment, the side wall of the main body 11 is provided with a plurality of conductive sheets 111, and the plurality of conductive sheets 111 are arranged at intervals along the circumference of the main body 11. In addition, the end of the conductive piece 111 away from the suction and discharge member 13 has an arc-shaped structure, which facilitates the conductive piece 111 to drive the connecting member 242 to move. In this embodiment, four conductive pieces 111 are provided on the side wall of the main body 11.

In order to seal the collection component, the collection member 10 further includes a collection head cover 14, and one end of the collection head cover 14 and the mixing member 20 is detachably connected. In addition, the collecting head cover 14 is provided with an escape hole, and the suction and discharge member 13 partially penetrates the escape hole. Specifically, the collecting head cover 14 may be connected to the mixing tube 22 through a threaded structure. When the collecting piece 10 is extended into the mixing tube 22, after the conductive structure connects the storage liquid chamber 21 with the mixing chamber, the collecting head cover 14 can be connected to the mixing tube 22 to make the mixing tube 22 The mixing chamber forms a closed structure. At this time, the mixing tube 22 can be shaken to mix the sample with the preservation solution. Specifically, the silicone suction head is connected to the main body 11, and the silicone suction head is nested and connected with the collecting head cover 14. In addition, the collecting head cover 14 can be assembled with the mixing tube 22 to realize the sealing of the mixing tube 22 and the hand-held part of the collecting piece 10.

As shown in Figure 7, the solid collection part 12 includes a plurality of convex walls 121, which are arranged at intervals along the circumferential direction of the collection end, and a sample collection area is formed between two adjacent convex walls 121, which can be set according to actual needs. The number of convex walls 121, for example, consists of 3, 5, 8 or 10 convex walls 121, and the space of the collection area can be set to the required size according to needs. When collecting solid feces with collection pieces The stool samples can be gathered in the sample collection area. When the solid stool fills the sample collection area of the solid collection part 12, the quantitative collection of the sample is completed. In this embodiment, the solid collecting portion 12 includes four convex walls 121, and the four convex walls 121 are evenly spaced along the circumferential direction of the collecting end. By setting the height of the solid collection part 12 and the width of the convex wall 121, quantitative collection of stool samples can be realized.

In order to facilitate mixing the stool sample with the preservation solution, a through hole 121a is provided on the surface of at least one convex wall 121, and the through hole 121a is in communication with the sample collection area. By providing a through hole 121a on the surface of the convex wall 121, when the stool sample needs to be mixed with the preservation solution, the preservation solution can flush the convex wall 121 through the through hole 121a to prevent the stool sample from sticking to the convex wall 121 It is difficult to fall, and the structure can facilitate the homogenization operation of the stool sample and the preservation solution. Specifically, due to the small size of the collection piece and the narrow structure of the convex wall 121, in order to increase the aperture as much as possible to allow the liquid and the sample to pass through the aperture, consider designing the through hole 121a as a rectangular small hole, which can also be used according to specific conditions. The through hole 121a is designed as a round hole or other hole type. The through holes 121a may be provided on the spaced convex walls 121 or on all the convex walls 121. In this embodiment, two of the four convex walls 121 arranged at intervals are provided with through holes 121a, and each convex wall 121 is provided with three rectangular small holes at intervals along the length direction.

Wherein, the convex wall 121 has a free end 121b and a connecting end 121c that are arranged oppositely, and the connecting end 121c of the convex wall 121 is connected with the side wall of the collecting end. By setting the thickness of the free end 121b to be smaller than the thickness of the connecting end 121c, on the one hand, when the collecting piece is used to collect solid feces, it is convenient to extend the solid collecting part 12 into the solid feces; on the other hand, when the collecting piece is rotated At this time, the resistance received by the convex wall 121 can be reduced, which facilitates sample collection.

Specifically, the convex walls 121 are bent in a direction away from the main body 11, and the bending direction of each convex wall 121 is the same. For example, all of the convex walls 121 may be bent in a clockwise direction, all in a counterclockwise direction, or other bending situations. In this embodiment, the convex wall 121 forms a wheel-shaped fan blade structure in a clockwise direction. Wherein, the opening direction, angle and number of the convex wall 121, the shape, diameter, number of holes on the convex wall 121, and the height of the convex wall 121 can be adjusted accordingly according to actual sampling requirements.

In addition, in order to seal the other end of the mixing element 20, the mixing element 20 further includes a mixing tube cover 26, and the mixing tube cover 26 is threadedly connected with the other end of the mixing tube 22 opposite to the collecting head cover 14.

Wherein, the mixing member 20 further includes mixing beads 27, which are movably arranged in the mixing tube 22, and the mixing beads 27 can be used to assist in mixing the sample and the preservation solution. In this embodiment, the mixing beads 27 include steel beads and glass beads. Specifically, the mixing ball 27 is a stainless steel ball with a diameter of 5-7 mm.

Specifically, the collection component 10 and the mixing component 20 can be combined into a set, and then placed separately and sent to the user. The collection component is mainly used for mixing and storing the sample.

As shown in FIG. 8, the present application provides another embodiment of the collection assembly. In this embodiment, the solid collection part 12 of the collection piece 10 can also adopt the structure design of the collection shell 15, and the collection shell 15 is set in the collection At the end, the collection shell 15 has a collection cavity, and the surface of the collection shell 15 has a porous structure. Set the space of the collection cavity to the required size according to the needs. With the above structure, when the solid feces is collected by the solid collection part 12, the solid feces can enter the collection cavity through the porous structure on the surface of the collection shell 15 to complete the sample. Quantitative collection. In this embodiment, the collection shell 15 has multiple ribs, and the multiple ribs are staggered, and there are multiple hole-shaped structures between the multiple ribs, so that the collection shell 15 has a porous surface and a certain accommodation space inside. Structure.

Specifically, the collection shell 15 has a spherical structure. When samples need to be collected, the spherical structure of the collection shell 15 does not need to adjust the direction of use of the solid collection part 12, which has the advantage of being convenient to use and can improve collection efficiency.

As shown in FIG. 2, another embodiment of the present application provides a collection device, which includes a collection component and a filter component 30. The collection component is the collection component provided above, the filter component 30 is detachably connected to the collection component, and the filter component 30 is used to filter the mixed liquid of the sample and the preservation solution. By separately setting the collection device into a collection component and a filter component 30, the user can use the collection component to collect samples, and the inspector can use the filter component 30 to filter the mixed liquid of the sample and the preservation solution collected by the user. Specifically, the filter assembly 30 can be used to filter food residues or other large particle residues in the sample, so as to improve the efficiency of subsequent sample pre-processing and detection.

As shown in FIGS. 4 to 6, the filter assembly 30 includes a filter tube 31 and a filter mesh 32. Wherein, the filter tube 31 has a first end and a second end which are arranged oppositely. The first end of the filter tube 31 is detachably connected to the mixing tube 22 of the collection assembly. The filter screen 32 is arranged in the filter tube 31, and the mixed liquid flows through When the filter mesh 32 is used, the filter mesh 32 can filter the mixed liquid, and the filter aperture of the filter mesh 32 is about 1 mm. In this embodiment, the filter mesh 32 and the filter tube 31 are integrally formed, which can ensure the stability of the device. In other embodiments, the filter mesh 32 may be provided as a separate component.

By setting the filter assembly 30, the filter assembly 30 can be used to filter the particles larger than the filter diameter in the feces. After the sample is filtered through the structure to filter out the residue of large particles, on the one hand, the preservation effect of the sample in the preservation solution can be improved to a certain extent, and the other On the one hand, it can prevent large particles from clogging the pipette tip and affecting the pipetting gun or pipetting instrument during subsequent testing and sampling.

In order to seal the collection assembly, the mixing member 20 of the collection assembly further includes a protective plug 25 which is clamped in the mixing tube 22 and is arranged close to the outlet of the mixing tube 22. After the user collects the sample with the collecting element 10, since the outlet of the mixing tube 22 is provided with a protective plug 25, and the inlet of the mixing tube 22 is provided with a collecting head cover 14, the mixing tube 22 can form a sealed structure, so that the mixed liquid will not Leakage from the collection component. Specifically, the protective plug 25 has a second blocking position and a second open position that are relatively disposed. When the protective plug 25 is located at the second blocking position, the protective plug 25 blocks the outlet of the mixing tube 22. By providing a boss 33 in the filter tube 31, the boss 33 is set corresponding to the protective plug 25. Since the position between the filter tube 31 and the mixing tube 22 is adjustable, by adjusting the distance between the filter tube 31 and the mixing tube 22 In the relative position of, the protection plug 25 can be driven by the boss 33 to move. When the protection plug 25 moves from the second blocking position to the second open position, the mixing tube 22 and the filter tube 31 are in communication. In addition, by providing the protective plug 25, the mixing tube can be maintained in the vertical direction for replacement during the process of connecting the filter tube by the inspector, and the liquid will not leak out.

Specifically, when the protective plug 25 is pushed into the mixing tube, due to the presence of the boss 33, even if centrifugal force is applied to accelerate the sample filtration, it will not cause the protective plug to block the lower nozzle or the filter, thereby blocking the sample. Flow into the filter tube.

Among them, a push-pull structure can be provided between the filter tube 31 and the mixing tube 22, and the relative position between the filter tube 31 and the mixing tube 22 can be adjusted by using the push-pull structure, or the filter tube 31 and the mixing tube 22 can be threaded Connection, by rotating the filter tube 31 relative to the mixing tube 22, the relative position between the filter tube 31 and the mixing tube 22 can be adjusted. In this embodiment, the filter tube 31 and the mixing tube 22 are threadedly connected.

In order to facilitate the collection of the filtered liquid, the collection device further includes a collection tube 40, the collection tube 40 is detachably connected to the filter assembly 30, and the collection tube 40 is used to collect the liquid filtered by the filter assembly 30. Wherein, the collection tube 40 and the second end of the filter tube 31 are detachably connected. Specifically, the collection tube 40 is threadedly connected to the second end of the filter tube 31.

Among them, a one-dimensional code or two-dimensional code can be printed on the bottom and sides of the filter tube 31 and/or the rear collection tube 40 for sample information tracking and recording. According to needs, the tube cover of the collection tube 40 can be a grooved hexagon, and the bottom of the tube can be hexagonal or hexagonal, so that the structure of the cover and the bottom of the tube can be fixed by the corresponding opening instrument and realize automatic opening of the instrument. The bottom of the tube is tapered, which is convenient for processing and taking biological samples.

The method of using the device provided in this embodiment is as follows:

A. Assembly

1) After the collection piece 10 is assembled according to the use requirements, it is placed in the sampling box separately;

2) After the mixing tube and the storage liquid tube, the steel ball and the mixing tube cover are assembled, they are separately placed in the sampling box;

3) The above two parts are sent to users for use;

4) The filter tube and the filter tube cover are assembled together and handed over to the inspector for storage and use.

B. User use

1) Take out the collection piece 10 from the sampling box to prepare for sampling;

2) Sampling: If the status of the stool sample is 1-6, extend the collection piece 10 vertically into the stool sample and rotate it 1-3 clockwise. In order to increase the diversity of samples, take samples at 2-3 positions according to the situation, and rotate 1-2 times clockwise at each position according to requirements. If collecting type 7 water-like samples, collect a proper amount of samples by squeezing the upper silicone tip, and the sample enters the hollow part of the solid collection part from the small hole at the bottom;

3) Take out the mixing tube from the collection box, and put the collection piece 10 into the mixing tube;

4) If it is the seventh type of sample, squeeze the collection piece 10 to release the sample into the mixing tube; then tighten the tube cover; if it is the 1-6 sample, tighten the tube cover directly;

5) After the preservation solution has all flowed into the bottom of the tube; invert and mix dozens of times to fully disperse and mix the sample in the preservation solution;

6) Contact logistics as required and send back samples.

C. Use by inspectors

1) The inspector takes out the filter tube (including the filter tube cover) in advance and puts it on the carrier;

2) After the inspector gets the above mixing tube containing the sample, remove the mixing tube cap at the bottom and set it aside;

3) Put the mixing tube into the filter tube cover and tighten it;

4) Place the assembled mixing tube and filter tube on the centrifugal device to speed up the sample filtration; or stand still to complete the sample filtration;

5) After all the liquid samples enter the collection tube through the filter, remove the filter tube cover and the mixing tube, and discard;

6) Replace with a new filter tube cover and tighten it;

7) Take the sample filtrate in the filter tube as needed for relevant sample testing.

By arranging the preservation liquid tube 23 in the mixing tube 22 and providing a conducting structure on the collection piece 10, the preserving liquid cavity 21 of the preserving liquid tube 23 and the mixing cavity of the mixing tube 22 can be connected by the conducting structure In this way, the preservation solution can be combined with the sample during the process of combining the collection element 10 and the mixing element 20, which can improve the sampling efficiency and reduce the risk of contamination of the preservation solution caused by the user's contact with the preservation solution.

It should be noted that the terms used here are only for describing specific embodiments, and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should also be understood that when the terms "comprising" and/or "including" are used in this specification, they indicate There are features, steps, operations, devices, components, and/or combinations thereof.

Unless specifically stated otherwise, the relative arrangement of components and steps, numerical expressions and numerical values set forth in these embodiments do not limit the scope of the present invention. At the same time, it should be understood that, for ease of description, the dimensions of the various parts shown in the drawings are not drawn in accordance with actual proportional relationships. The technologies, methods, and equipment known to those of ordinary skill in the relevant fields may not be discussed in detail, but where appropriate, the technologies, methods, and equipment should be regarded as part of the authorization specification. In all examples shown and discussed here, any specific value should be interpreted as merely exemplary, rather than as a limitation. Therefore, other examples of the exemplary embodiment may have different values. It should be noted that similar reference numerals and letters indicate similar items in the following drawings, so once a certain item is defined in one drawing, it does not need to be further discussed in subsequent drawings.

In the description of the present invention, it needs to be understood that orientation words such as "front, back, up, down, left, right", "horizontal, vertical, vertical, horizontal" and "top, bottom", etc. indicate the orientation Or positional relationship is usually based on the positional or positional relationship shown in the drawings, which is only used to facilitate the description of the present invention and simplify the description. Unless otherwise stated, these positional words do not indicate or imply the pointed device or element It must have a specific orientation or be constructed and operated in a specific orientation, so it cannot be understood as a limitation of the protection scope of the present invention; the orientation word "inside and outside" refers to the inside and outside relative to the contour of each component itself.

For ease of description, spatially relative terms such as "above", "above", "above", "above", etc. can be used here to describe as shown in the figure. Shows the spatial positional relationship between one device or feature and other devices or features. It should be understood that the spatially relative terms are intended to encompass different orientations in use or operation other than the orientation of the device described in the figure. For example, if the device in the figure is inverted, then the device described as "above the other device or structure" or "above the other device or structure" will then be positioned as "below the other device or structure" or "on Under other devices or structures". Thus, the exemplary term "above" can include both orientations "above" and "below". The device can also be positioned in other different ways (rotated by 90 degrees or in other orientations), and the relative description of the space used here is explained accordingly.

In addition, it should be noted that the use of terms such as "first" and "second" to define parts is only for the convenience of distinguishing the corresponding parts. Unless otherwise stated, the above terms have no special meaning and therefore cannot be understood. To limit the protection scope of the present invention.

The above descriptions are only preferred embodiments of the application, and are not used to limit the application. For those skilled in the art, the application can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of this application shall be included in the protection scope of this application.

Industrial applicability

Applying the technical solution of the present application, the collection component includes a collection part and a mixing part. Wherein, the collecting piece is provided with a conducting structure, the collecting piece is used for collecting samples, and the collecting piece has a avoiding position and a conducting position relative to the mixing piece. By making the mixing member have a mixing cavity and a storage chamber that are set independently of each other, after the collection member is used to complete the sample collection, only the collection member needs to be moved to the conductive position, and the conductive structure on the collection member can be used to The storage solution chamber is connected to the mixing chamber, so that the storage solution in the storage solution chamber can flow into the mixing chamber, so that the sample and the storage solution can be mixed in the mixing chamber. The above device eliminates the need for staff Injecting the preservation solution into the mixing piece can simplify the collection steps, thereby improving the collection efficiency, and the preservation solution will not have the risk of spilling during the inflow process, ensuring the normal mixing of the sample.

Claims

A collection component, wherein the collection component includes:

The collecting piece (10) is provided with a conducting structure, and the collecting piece (10) is used for collecting samples;

The mixing member (20) has a mixing cavity and a storage solution cavity (21) that are independently set up, the mixing cavity is used for mixing the sample and the storage solution, and the storage solution cavity (21) is used for storing The preservation solution;

Wherein, the collecting member (10) has a avoiding position and a conducting position relative to the mixing member (20). When the collecting member (10) is located at the avoiding position, the storage liquid chamber (21) Is in a sealed state; when the collecting member (10) is located at the conducting position, the conducting structure can conduct the storage liquid chamber (21) with the mixing chamber to connect the storage liquid The preservation solution in the cavity (21) is conducted to the mixing cavity.
The collection assembly according to claim 1, wherein the mixing member (20) comprises a mixing tube (22) and a preservation liquid tube (23) connected to each other, and the preservation liquid tube (23) has the preservation A liquid cavity (21), and the mixing tube (22) has the mixing cavity.
The collection assembly according to claim 2, wherein the preservation liquid tube (23) has a double-walled tube structure, and the preservation liquid tube (23) has an inner layer (231) and an outer layer (232) arranged oppositely There is an interval between the inner layer (231) and the outer layer (232), and the interval forms the preservation liquid cavity (21).
The collection assembly according to claim 3, wherein the preservation liquid chamber (21) has a first end and a second end which are arranged oppositely, and the first end of the preservation liquid chamber (21) is close to the collection piece ( 10) Setting, the first end of the preservation liquid chamber (21) is a closed structure, the second end of the preservation liquid chamber (21) is an open structure, and the preservation liquid chamber (21) can pass through the opening structure In communication with the mixing cavity, the mixing member (20) further includes a blocking component (24), the blocking component (24) is disposed at the opening structure, and the blocking component (24) It is used to close the storage liquid cavity (21), and the blocking assembly (24) has a blocked state and an open state. When the collecting member (10) moves from the avoiding position to the conducting position, The conducting structure cooperates with the blocking component (24) to switch the blocking component (24) from the blocking state to the open state.
The collection assembly according to claim 4, wherein the blocking assembly (24) comprises:

The sealing member (241) is arranged at the second end of the preservation liquid chamber (21);

The connecting piece (242) is arranged at the second end of the preservation liquid chamber (21), the sealing piece (241) seals the opening structure through the connecting piece (242), and the connecting piece (242) has The first blocking position and the first open position are relatively set, and the conduction structure is used to drive the connecting member (242) to move from the first blocking position to the first open position, when the connection When the member (242) is located in the first open position, the preservation liquid chamber (21) is in communication with the mixing chamber, the connecting member (242) is clamped on the inner layer (231), and the The sealing element (241) has a ring structure, the outer edge of the sealing element (241) is connected to the end surface of the outer layer (232), and the inner edge of the sealing element (241) is connected to the connecting element (242) through the The end faces of the inner layer (231) are connected.
The collection assembly according to claim 2, wherein the mixing tube (22) comprises a first section and a second section that are connected to each other, and the first section of the mixing tube (22) is close to the collection piece ( 10) Setting that the cross-sectional size of the first section of the mixing tube (22) is greater than the cross-sectional size of the second section of the mixing tube (22), and the preservation liquid tube (23) is located in the mixing tube (22). In the first section of the even pipe (22).
The collection assembly according to claim 1, wherein the collection piece (10) comprises:

The main body (11) has a holding end and a collecting end that are arranged oppositely, the conducting structure is arranged on the main body (11), and the collecting end is provided with a collecting hole;

The solid collection part (12) is arranged at the collection end, and the solid collection part (12) is used for collecting solid samples;

The suction and discharge member (13) is arranged on the holding end and communicates with the collection hole, and the suction and discharge member (13) sucks or discharges a liquid sample through the collection hole.
The collection assembly according to claim 7, wherein a conductive sheet (111) is provided on the side wall of the main body (11), and the extending direction of the conductive sheet (111) is the same as that of the main body (11). The axial directions are the same, and the conductive sheet (111) forms the conductive structure.
The collection assembly according to claim 7, wherein the collection piece (10) further comprises a collection head cover (14), the collection head cover (14) and one end of the mixing piece (20) are detachably connected An escape hole is provided on the collecting head cover (14), and the suction and discharge member (13) partially penetrates the escape hole.
The collection assembly according to claim 7, wherein the solid collection part (12) comprises a plurality of convex walls (121), and the plurality of convex walls (121) are arranged at intervals along the circumferential direction of the collection end, adjacent to each other. A sample collection area is formed between the two convex walls (121).
The collection assembly of claim 10, wherein:

A through hole (121a) is provided on the surface of at least one of the convex walls (121), and the through hole (121a) is in communication with the sample collection area; and/or,

The convex wall (121) has a free end (121b) and a connecting end (121c) that are oppositely arranged. The connecting end (121c) of the convex wall (121) is connected to the side wall of the collecting end, and the free end ( The thickness of 121b) is less than the thickness of the connecting end (121c); and/or,

The convex wall (121) is bent in a direction away from the body (11), and the bending direction of each convex wall (121) is the same.
The collection assembly according to claim 7, wherein the solid collection part (12) comprises:

The collecting shell (15) is sleeved on the collecting end, the collecting shell (15) is provided with a collecting cavity, and the surface of the collecting shell (15) is a porous structure.
The collection assembly according to claim 12, wherein the collection shell (15) has a spherical structure.
An acquisition device, wherein the acquisition device includes:

A collection component, the collection component being the collection component according to any one of claims 1 to 13;

The filter component (30) is detachably connected with the collection component, and the filter component (30) is used for filtering the mixed liquid of the sample and the preservation solution.
The collection device according to claim 14, wherein the filtering component (30) comprises:

The filter tube (31) has a first end and a second end that are arranged oppositely, and the first end of the filter tube (31) is detachably connected to the mixing tube (22) of the collection assembly;

The filter screen (32) is arranged in the filter tube (31);

The mixing piece (20) of the collection assembly further includes a protective plug (25), the protective plug (25) is clamped in the mixing tube (22) and close to the mixing tube (22) The outlet is provided, the protective plug (25) has a second blocking position and a second open position that are relatively set, and when the protective plug (25) is located at the second blocking position, the protective plug (25) Block the outlet of the mixing tube (22), the filter tube (31) is provided with a boss (33), the boss (33) is arranged corresponding to the protective plug (25), and the filter tube The position between (31) and the mixing tube (22) is adjustable. By adjusting the relative position between the filter tube (31) and the mixing tube (22), the boss ( 33) Drive the protective plug (25) to move.
The collection device according to claim 14, wherein the collection device further comprises a collection tube (40), the collection tube (40) is detachably connected to the filter assembly (30), and the collection tube (40) It is used to collect the liquid filtered by the filter assembly (30).