WO2020235824A3 - 뇌 이상 단백질 치료를 위한 방사선 치료 시스템 및 이의 치료 방법 - Google Patents

뇌 이상 단백질 치료를 위한 방사선 치료 시스템 및 이의 치료 방법 Download PDF

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Publication number
WO2020235824A3
WO2020235824A3 PCT/KR2020/005435 KR2020005435W WO2020235824A3 WO 2020235824 A3 WO2020235824 A3 WO 2020235824A3 KR 2020005435 W KR2020005435 W KR 2020005435W WO 2020235824 A3 WO2020235824 A3 WO 2020235824A3
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Prior art keywords
radiation
brain
radiotherapy system
treating abnormal
treatment method
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PCT/KR2020/005435
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English (en)
French (fr)
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WO2020235824A2 (ko
Inventor
장건호
정원규
신동오
김동욱
Original Assignee
경희대학교산학협력단
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Publication of WO2020235824A2 publication Critical patent/WO2020235824A2/ko
Publication of WO2020235824A3 publication Critical patent/WO2020235824A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1042—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head
    • A61N5/1045—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087—Ions; Protons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/109—Neutrons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1094—Shielding, protecting against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1096—Elements inserted into the radiation path placed on the patient, e.g. bags, bolus, compensators

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

개시된 본 발명에 의한 뇌 이상 단백질 치료를 위한 방사선 치료 시스템은, 환자의 뇌로 전리 방사선을 조사하여 뇌 단백질을 감소시켜 미세아교세포(microglia cell)의 기능을 회복시키는 방사선부 및 방사선부로부터 조사되는 방사선의 총량 및 횟수를 제어하는 제어부를 포함하며, 제어부는 뇌로 기 설정된 저선량 또는 극저선량 방사선 중 적어도 어느 하나의 범위의 총 방사선량을 복수의 횟수로 분할하여 조사하도록 제어한다. 이러한 구성에 의하면, 뇌 단백질 치료로 인한 인지기능을 향상시킬 수 있게 된다.
PCT/KR2020/005435 2019-05-22 2020-04-24 뇌 이상 단백질 치료를 위한 방사선 치료 시스템 및 이의 치료 방법 WO2020235824A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2019-0060110 2019-05-22
KR1020190060110A KR102272858B1 (ko) 2019-05-22 2019-05-22 뇌 이상 단백질 치료를 위한 방사선 시스템 및 이의 사용 방법

Publications (2)

Publication Number Publication Date
WO2020235824A2 WO2020235824A2 (ko) 2020-11-26
WO2020235824A3 true WO2020235824A3 (ko) 2021-02-04

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PCT/KR2020/005435 WO2020235824A2 (ko) 2019-05-22 2020-04-24 뇌 이상 단백질 치료를 위한 방사선 치료 시스템 및 이의 치료 방법

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KR (1) KR102272858B1 (ko)
WO (1) WO2020235824A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230061121A (ko) * 2021-10-28 2023-05-08 경희대학교 산학협력단 저선량 전리방사선 치료장치
WO2024029862A1 (ko) * 2022-08-01 2024-02-08 경희대학교 산학협력단 광자 에너지 빔 방출 형태에 따른 치매, 만성 염증 치료를 위한 저선량 방사선 치료시스템
WO2024029861A1 (ko) * 2022-08-01 2024-02-08 경희대학교 산학협력단 광자 에너지 빔 방출 형태에 따른 치매, 만성 염증 치료를 위한 저선량 방사선 치료시스템

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100016841A1 (en) * 2006-01-30 2010-01-21 Luis De Taboada Light-emitting device and method for providing phototherapy to the brain
US20130323166A1 (en) * 2010-09-10 2013-12-05 William Beaumont Hospital Radiation Therapy for Treating Alzheimer's Disease
KR20150096395A (ko) * 2012-12-10 2015-08-24 오르피트 인더스트리즈 고정 마스크의 부착을 위한 프로파일
JP5807869B2 (ja) * 2011-04-18 2015-11-10 公益財団法人ヒューマンサイエンス振興財団 放射線プロテクタ
US20160367837A1 (en) * 2015-06-16 2016-12-22 Eugene R. Moore Treatment of Alzheimer's disease
KR20190045136A (ko) * 2019-04-24 2019-05-02 한국수력원자력 주식회사 저선량 방사선을 이용한 초파리의 퇴행성 질환 증상을 완화시키는 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2859605T3 (es) 2013-07-26 2021-10-04 Univ Iowa Res Found Procedimientos y composiciones para tratar enfermedades del cerebro
EP4218916A1 (en) 2015-11-24 2023-08-02 Massachusetts Institute of Technology System for treating dementia

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100016841A1 (en) * 2006-01-30 2010-01-21 Luis De Taboada Light-emitting device and method for providing phototherapy to the brain
US20130323166A1 (en) * 2010-09-10 2013-12-05 William Beaumont Hospital Radiation Therapy for Treating Alzheimer's Disease
JP5807869B2 (ja) * 2011-04-18 2015-11-10 公益財団法人ヒューマンサイエンス振興財団 放射線プロテクタ
KR20150096395A (ko) * 2012-12-10 2015-08-24 오르피트 인더스트리즈 고정 마스크의 부착을 위한 프로파일
US20160367837A1 (en) * 2015-06-16 2016-12-22 Eugene R. Moore Treatment of Alzheimer's disease
KR20190045136A (ko) * 2019-04-24 2019-05-02 한국수력원자력 주식회사 저선량 방사선을 이용한 초파리의 퇴행성 질환 증상을 완화시키는 방법

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KR102272858B1 (ko) 2021-07-05
KR20200134540A (ko) 2020-12-02
WO2020235824A2 (ko) 2020-11-26

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