WO2020209314A1 - Medical fluid injector and medical fluid injecting device comprising same - Google Patents

Abstract

This injection head 110 is for mounting a medical fluid syringe 200B, the medical fluid syringe 200B is to be filled with medical fluid and includes a tubular cylinder member 230 and a piston member 240 that is freely slidably inserted therein. The cylinder member 230 is formed such that the shape of a cross section thereof taken in a plane orthogonal to the axis thereof is substantially elliptical, and a cylinder flange 231 is provided on the end on the side where the piston member 240 is inserted. On the rear face of the cylinder flange 231, an engaging projection or an engaging recess 239 with which an engaging member of the medical fluid injector engages is formed.

Description

Chemical injection device and chemical injection device equipped with it

The present invention relates to a drug solution injector and a drug solution injection device that hold a plurality of drug solution syringes and deliver the drug solution to a subject, and more particularly to a drug solution injector and a drug solution injection device that can be compactly configured.

Currently, CT (Computed Tomography) scanners, MRI (Magnetic Resonance Imaging) devices, PET (Positron Emission Tomography) devices, ultrasonic diagnostic devices, angiography (angiography) imaging devices, etc. are known as medical diagnostic imaging devices. ing. When using such an imaging device, a contrast medium, physiological saline, or the like (hereinafter, these are also simply referred to as “chemical solutions”) may be injected into the subject.

Conventionally, various devices have been known as devices for automatically injecting a chemical solution. The configuration and performance of the device differ depending on what kind of inspection the device is used for (in other words, what kind of imaging device it is used with), etc., but in the case of MRI inspection, for example, A contrast medium injection device that injects a gadolinium-based contrast medium is used. In this contrast medium injection device, for example, a non-magnetic ultrasonic motor is used as the drive source of the piston drive mechanism so as not to affect the image pickup by the MRI device. Further, a drug solution injection device equipped with two syringes of a physiological saline solution and a contrast medium and simultaneously injecting them as needed is also conventionally known (see, for example, Patent Document 1).

JP-A-2017-77349

The injection head of Patent Document 1 holds two syringes in parallel, but the size of the syringe holding portion of the injection head and its peripheral structure is relatively large, and there is room for further improvement in terms of miniaturization. Has been done. Miniaturization of the injection head (chemical injection device) for injecting the contrast medium is also preferable from the viewpoint of reducing the psychological burden on the subject to whom the contrast medium is injected.

The present invention has been made in view of the above problems, and an object of the present invention is a drug solution injector that can be compactly configured in a drug solution injector that holds a plurality of drug solution syringes and delivers the drug solution to a subject. Etc. are to be provided.

A chemical injector according to one embodiment of the present invention for solving the above problems is as follows:
A first piston drive mechanism having a ram member that moves back and forth to move the piston member of the first syringe,
A second piston drive mechanism having a ram member that moves back and forth to move the piston member of the second syringe,
A syringe holder for holding the first and second syringes, and
With
The syringe holder is provided at the tip of a center frame arranged so as to extend between the two ram members.

(Explanation of terms)
-"Chemical solution injection device" means a chemical solution injection device that injects a chemical solution, and may include the following components: one or more piston drive mechanisms, one or more control circuits (control). One or more head displays and one or more displays. When the chemical injection device includes an injection head, a console, and the like, the injection head may be provided with a piston drive mechanism and a control circuit for controlling the piston drive mechanism, and the console may be provided with a display and a control circuit for controlling the piston drive mechanism.
-"Chemical solution" means, for example, a contrast medium, physiological saline, a predetermined drug, or a mixture thereof.
-For terms indicating direction, "front" corresponds to the tip side of the syringe and "rear" corresponds to the opposite side. The injection head is held rotatably around a horizontal axis, for example, (i) a posture during use in which the tip side of the syringe faces downward from the horizontal, and (ii) a posture when sucking a drug solution into the syringe. It is possible to switch to the non-use posture in which the tip side of the syringe faces vertically upward. In the present specification, for convenience of explanation, the syringe will be described with reference to a horizontal posture (in this posture, the ram member of the piston drive mechanism is also horizontal).

-As the "imaging device", for example, an MRI (Magnetic Resonance Imaging) device, a CT (Computed Tomography) device, an angio imaging device, a PET (Positron Emission Tomography) device, a SPECT (Single Photon) device, and a SPECT (Single Photon) device. , MR angio device, ultrasonic diagnostic device, and angiography device.

-Regarding the "syringe", the syringe may be attached with an IC tag. The IC tag contains information about the syringe (syringe identification information, syringe pressure resistance, cylinder member inner diameter, piston member stroke, etc.), information on the chemical solution filled in the syringe (name (for example, product name), iodine amount). Alternatively, component information such as the amount of gadolinium, expiration date, chemical volume, etc.) may be stored. Not limited to the IC tag, other data holding media such as a barcode may be used.

According to the present invention, it is possible to provide a drug solution injector or the like that can be compactly configured in a drug solution injector that holds a plurality of drug solution syringes and delivers the drug solution to a subject.

It is a perspective view of the injection head of one Embodiment of this invention (syringe attached state). It is a perspective view which shows the structure of the injection head of FIG. 1A. It is a block diagram which shows the structure of the chemical liquid injection apparatus. It is a perspective view which shows the 1st syringe and a syringe adapter. It is a perspective view which shows the cylinder of the 2nd syringe formed in an elliptical shape. It is a perspective view which shows the piston member of the 2nd syringe. It is a perspective view for demonstrating the structure of the rear surface of a cylinder flange. It is a rear view for demonstrating the structure of the rear surface of a cylinder flange. It is a perspective view which shows the syringe holder. It is a figure which shows only the member on the rear side among the members of a syringe holder. It is a top view which looked at the state which the cylinder flange was inserted into a syringe holder from the upper side. It is a perspective view for demonstrating the structure of the engaging member. It is a perspective view which shows the presser member provided in the tip part of the ram member, and the flange gripping mechanism provided in the front end part thereof. It is a top view which saw the presser member and the flange gripping mechanism from the upper side. It is a figure which shows only a pair of rotating claws (initial state). It is a perspective view for demonstrating the relationship between a rotary claw and a piston flange. It is a front view for demonstrating the relationship between a rotary claw and a piston flange. It is a figure which shows an example of the case where a pair of rotary claws are configured so that it can expand in the radial direction of a piston flange. It is a figure which shows the operation which the piston flange is gripped by a pair of rotary claws (front view). It is a figure which shows the operation which the piston flange is gripped by a pair of rotary claws (plan view). It is a perspective view which shows the structural example of a syringe adapter (the state seen from the front side). It is a perspective view which shows the structural example of a syringe adapter (the state seen from the rear side). It is a perspective view which shows an example of the holding stand of an injection head and a head display. It is a perspective view which shows the detail of a holding stand. It is a perspective view which shows an example of a console. It is a perspective view which looked at the chemical liquid injector from the front side. It is a perspective view which looked at the chemical liquid injector from the back side. It is a front view of a chemical injection device. It is a rear view of a chemical injection device. It is a top view of the chemical injection device. It is a bottom view of a chemical injection device. It is a right side view of a chemical injector. It is a left side view of a chemical injection device. It is a reference view which looked at the chemical liquid injector from the front side (the state which the 1st syringe was attached to the syringe holder via an adapter, and the 2nd syringe was attached to a syringe holder without passing through an adapter). It is a figure which shows another example of an elliptical syringe. It is a figure which shows another example of an elliptical syringe, (a) is the view which looked at the conduit part side, (b) is the figure which looked at the piston member side, (c) is the figure which looked at the cylinder flange from the upper surface side. is there. It is a figure which shows the gasket alone. It is a figure which shows the cylinder member independently. It is a figure which shows the structural example of the conduit part. It is a schematic cross-sectional view of a syringe before inserting a ram into a hole of a sucker. It is the schematic sectional drawing of the syringe in the state which the ram is inserted into the hole of a sucker. It is the schematic sectional drawing of the syringe in the state which the ram and the gasket are connected. It is a schematic exploded perspective view of the syringe which concerns on another aspect. It is a figure which shows the configuration example of the injection head which can hold an elliptical type syringe by the front loading method. This is an example of an adapter for setting a general-purpose syringe with respect to the injection head of FIG. 43. It is a schematic diagram for demonstrating the operation example of the opening / closing valve and the like when the piston of a syringe is not held. It is a schematic diagram which shows the structure which enables the chemical solution filling from the chemical solution container into a syringe (chemical solution container).

One embodiment of the present invention will be described below with reference to the drawings. In the following, specific examples of the chemical injection device are disclosed, but the present invention is not necessarily limited to these specific configurations. In the following, the configuration of the device or the device will be basically described with reference numerals in the drawings, but for convenience of explanation, the reference numerals may be omitted.

As shown in FIGS. 1A, 1B, and 2, the chemical solution injection device 100 of the present embodiment is for injecting a chemical solution such as a contrast medium toward the subject via the chemical solution circuit 900, and the injection head 110. And console 150. First, the configuration of the entire chemical injection device including the injection head 110 will be described, and then the specific structure of the injection head 110 will be described with reference to other drawings.

(Injection head)
The injection head 110 is, for example, for an MRI examination. The injection head 110 is a two-cylinder type to which two syringes 200A and 200B can be attached. One syringe 200A is filled with a contrast medium, and the other syringe 200B is filled with physiological saline. The present invention is not necessarily limited to the injection head for MRI examination, and can be applied to the injection head for CT examination and angiography examination. In the present specification, the syringes 200A and 200B may be referred to as a first syringe and a second syringe, respectively, or they may be simply referred to as a syringe 200 without distinguishing them. Various mechanisms on the syringe 200A side may be expressed as "mechanisms on the A side", and various mechanisms on the syringe 200B side may be expressed as "mechanisms on the B side". The second syringe 200B may be filled with another chemical solution instead of the physiological saline solution.

The injection head 110 has a housing 111 as shown in FIG. 1A, and a ram member 133 of the piston drive mechanism 130 for moving the piston members of the syringes 200A and 200B protrudes from the front end of the housing 111. At the same time, a syringe holder 170 for holding the syringes 200A and 200B is provided.

A plurality of physical buttons 161 for causing the injection head 110 to perform various operations are provided on the housing 111. The physical button 161 is not particularly limited, but may be: a forward button for advancing the ram member of the piston drive mechanism, a retract button for retracting the ram member, a forward button or a retract button. An accelerator button that speeds up the movement of the ram member by pressing it at the same time, and a stop button that stops the movement of the head. The housing 111, the physical button 161 and / or the structure around the button are water-repellent (for example, coating, painting, attaching a protective member, etc.) to prevent adhesion even if a chemical solution is dropped. It may be done. Further, according to such a configuration, it is possible to prevent the chemical solution from entering the injection head.

As schematically shown in FIG. 2, the piston drive 130 is connected to a motor 131, which is a drive source, a transmission mechanism 132 that transmits the rotational output of the drive motor and converts it into linear motion, and a syringe. It has a ram member 133 that advances and / or retracts the piston member of the above. Specifically, the transmission mechanism 132 includes a transmission element connected to the shaft of the motor, a screw shaft connected to the transmission element, a trapezoidal screw nut attached to the screw shaft, and a drive element connected to the trapezoidal screw nut. And may have. The transmission mechanism transmits the rotation from the motor to the screw shaft, which rotates the screw shaft, and the action of the trapezoidal screw nut causes the drive element to move in the forward direction or the reverse direction.

In the case of an MRI inspection device, a non-magnetic material is used for the parts constituting the injection head 110. For example, examples of the non-magnetic material include stainless steel, aluminum, plastic, brass, copper, and cellamix. The motor 131 may be an ultrasonic motor constructed by using a non-magnetic material. In this ultrasonic motor, for example, the elastic body is made of phosphor bronze, the shaft, screws and spacers are made of brass, the case, base and rotor are made of aluminum, and the bush is made of fluororesin. There may be.

The injection head 110 may be provided with a load cell 138 (see FIG. 2) for detecting the force with which the ram member 133 presses the piston member of the syringe. Using the detection result of the load cell 138, it is possible to obtain an estimated value of the pressure of the chemical solution when the chemical solution is being injected. The calculation of this estimated value may be performed in consideration of the needle size, the concentration of the drug solution, the injection conditions, and the like. Alternatively, the pressure may be calculated based on the motor current of the motor 131 instead of using the load cell 138.

(console)
As shown in FIG. 2, the console 150 includes a display 151 for displaying a graphical user interface and the like, a touch panel 153, a control unit 155, one or more physical switches 157, and a storage unit which is a storage medium such as a hard disk. It may have 159. As an example, one of these elements may be provided in a housing (not shown), and the console 150 may be provided as a device separate from the injection head 110. The console 150 is configured to be connected to the injection head 110 by a wired connection or a wireless connection so that data can be transmitted and received to and from the injection head 110. The console 150 may also have a data transmission / reception unit (not shown) that transmits and / or receives data to an external network or device. Regarding the console, it is not an essential matter that one element as described above is integrally provided in the housing, and for example, a control unit, a display, and the like may be configured as separate devices. A specific configuration example of the console will be described later with reference to other drawings.

The control unit 155 has a function of controlling the creation of the injection protocol, the execution of the injection, and the like, and includes, for example, a setting screen display function, an injection protocol creation function, an injection control function, a history generation function, a history output function, and the like. You may be.

The setting screen display function displays a screen for setting the injection protocol, specifically, a graphical user interface for setting the injection protocol on the display 151 and / or another display (for example, the injection head 151 described later with reference to FIG. 22). It corresponds to the function of displaying on the head display provided in the vicinity of -1.

The injection protocol creation function corresponds to, for example, a function of accepting an input operation on the touch panel 153 of the display 151 by a doctor or a medical worker (simply referred to as an operator) and creating an injection protocol reflecting the contents thereof. .. In the protocol creation function, for example, information selected from the type of drug solution, injection rate of drug solution, injection amount of drug solution, physical information (for example, body weight) of the subject, body classification of the subject to be imaged, imaging site, biological information of the subject, etc. Based on, the predetermined parameters of the injection protocol are calculated accordingly.

The injection control function corresponds to the function of controlling the operation of the piston drive mechanism (details below) according to the created injection protocol. The injection control unit operates only one of the piston drive mechanisms and operates both at the same time. The injection control function may be performed by the control circuit 115 of the injection head 110.

The history generation function corresponds to the function of generating injection history data (chemical solution injection data). The “injection history data” includes, for example, an injection work ID which is unique identification information for each injection operation, dates and times of injection start and end, identification information of a drug solution injection device, contrast medium and / or physiological saline injection conditions. It may be at least one of the injection result of the contrast medium and / or the physiological saline, and the identification information of the drug solution or the imaging site. The history output function corresponds to a function of transmitting injection history data to the outside. Specifically, the data may be transmitted to a predetermined external device and / or a database on the network.

The storage unit 159 may store, for example, an image displayed on a display, data of a graphical user interface, or the like. Further, an algorithm including a calculation formula for setting injection conditions and data of the injection protocol may be stored.

The injection head 110 of this embodiment has some technical features such as:
(A) Elliptical syringe and syringe holder (B) Specific structure of center frame and piston drive mechanism (C) Piston flange gripping mechanism The basic configurations of syringes 200A and 200B mounted on the injection head 110 have been described below. Later, the above technical features will be described in order.

(Syringe)
Regarding the syringe, the first syringe 200A and the second syringe 200B may have the same shape, but in the present embodiment, the first syringe 200A filled with the contrast medium in a relatively small size and more. A second syringe 200B, which is formed to a large size and filled with saline, is used. The syringe may be a prefilled type filled with a chemical solution in advance, or may be a suction type syringe used by sucking the chemical solution into an empty syringe.

As shown in FIG. 3, the first syringe 200A has a hollow cylindrical cylinder member 210 and a piston member 220 slidably inserted into the cylinder member 210. A conduit portion 213 is formed at the front end portion of the cylinder member 210, and a cylinder flange 211 is formed at the rear end portion of the cylinder member 210. A gasket (not shown) is provided at the tip of the piston member 220, and a disk-shaped piston flange 221 is formed at the rear end as an example. The first syringe 200A may be held by the injection head 110 via the syringe adapter 270.

The first syringe 200A is filled with a contrast medium for MRI examination. Although not limited, the volume of the syringe 200A may be about 50 ml or less. In FIG. 3, the syringe 200A is drawn in a posture in which the cylinder flange 211 extends in the vertical direction, but it is configured to be attached to the syringe adapter 270 in a posture in which the cylinder flange extends in the horizontal direction. You may. A specific configuration example of the syringe adapter 270 will be described later with reference to another drawing.

As shown in FIGS. 4 to 7, the second syringe 200B also has a hollow cylinder-shaped cylinder member 230 and a piston member 240 slidably inserted into the cylinder member 230. As a matter common to the first and second syringes, the piston member is not necessarily limited to a long rod as shown in the figure, but is a so-called rodless type (may be simply referred to as a "plunger" or the like). It may be. The shape of the syringe is not particularly limited, but in the second syringe 200B of the present embodiment, a syringe having an elliptical cross-sectional shape in a plane perpendicular to the axial direction of the syringe is used.

As shown in FIG. 4, a conduit portion 233 is formed at the front end portion of the cylinder member 230, and a cylinder flange 231 is formed at the rear end portion. As shown in FIG. 5, the piston member 240 includes an insertion cylinder portion 243 having an elliptical cross-sectional shape, and a shaft portion 247 extending from the insertion cylinder portion 243 to the rear side. A gasket 245 is provided at the tip of the insertion cylinder portion 243. A disk-shaped piston flange 241 is formed at the rear end of the shaft portion 247.

As shown in FIGS. 6 and 7, the cross-sectional shape of the internal space 230s of the cylinder member 230 is elliptical, and the insertion cylinder portion 243 of the piston member 240 is inserted into the internal space 230s. The cylinder flange 231 may be formed in an elliptical shape, but in the present embodiment, the cylinder flange 231 is formed in a substantially egg-shaped contour, and is designed so that the overhanging dimension from the tubular portion differs between the upper part and the lower part. Although not limited, the cylinder flange 231 is configured to be set in the syringe holder 170 described later in the orientation shown in FIGS. 6 and 7 (the direction in which the lower part in the drawing is the protruding side of the egg shape). ..

The plate thickness of the cylinder flange 231 is constant, and an elliptical rib 236 slightly protruding from the same surface is formed on the rear surface. The rib 236 is formed in a shape along the opening of the cylinder member 230. Further, on the rear surface of the cylinder flange 231, two flange ribs 237 and 237 extending in the horizontal direction are formed on both the left and right sides. The "horizontal direction" is a direction orthogonal to the direction (vertical direction) in which the cylinder flange 231 is inserted into the syringe holder 170.

As shown in FIG. 7, flange ribs 237 may be formed in parallel above and below the center line L2 so as to sandwich the horizontal center line L2 passing through the center of the syringe. A locking recess 239 into which a locking member of a syringe holder, which will be described later, is fitted is formed between the two flange ribs 237.

As shown in FIG. 7, the cylinder flange 231 itself has a substantially egg shape and is vertically asymmetrical, but the two upper and lower flange ribs 237 may be formed symmetrically with the center line L2 in between. Further, the two flange ribs 237 on the right side and the two flange ribs 237 on the left side may be formed symmetrically with the center line L1 in the vertical direction in between.

(A: Syringe holder)
Subsequently, the syringe holder 170 will be described with reference to FIGS. 8 to 10. The syringe holder 170 is provided one by one so as to correspond to each of the syringes 200A and B, and has basically the same structure. Here, the syringe holder 170 corresponding to the syringe 200B will be described as an example.

In this example, the syringe holder 170 is formed in a substantially U shape as a whole, and is composed of a first member 171 located on the front side of the injection head and a second member 173 located on the rear side. However, as described above, the present invention is not limited to two members, and may be composed of a single member or a plurality of three or more members. The materials of these members 171 and 173 are not particularly limited, but may be made of resin or metal. The syringe holder 170 has a receiving groove 175 that receives the cylinder flange 231. As an example, the receiving groove 175 may have a substantially U-shape having a shape complementary to the outer shape of the cylinder flange 231.

Note that FIG. 9 is a view of the second member 173 viewed from the front side of the injection head. In this example, the bottom portion of the receiving groove 175 is an opening 175h, and the cylinder flange 231 is In the set state, the lowermost portion of the cylinder flange 231 slightly protrudes downward from the bottom portion of the syringe holder 170. Although it is not always necessary to have such a configuration, the structure of such a syringe holder 170 is advantageous in that it is possible to reduce the size by removing a part of the holder. The opening 175h may also serve to allow the liquid to escape through the opening 175h when the liquid spills onto the holder.

As shown in FIGS. 8 and 9, engaging members 176 that fit into the engaging recesses 239 of the cylinder flange 231 are provided on both the left and right sides of the receiving groove 175. The engaging member 176 may have any shape as long as it gets over the rib 237 of the cylinder flange 231 and fits into the engaging recess 239 when the syringe is mounted, and the engaging member 176 may have any shape. It may be a structural portion in which a part is projected, or it may be a member different from the second member 173.

As an example, as shown in FIG. 11, an engaging member 176 that is separate from the second member 173 may be attached to a part of the second member 173. Specifically, the engaging member 176 is fitted into the hole 173h formed in the second member 173 from the rear surface side of the second member 173, and a part of the engaging member 176 projects into the receiving groove 175. It may be provided in.

The material of the engaging member 176 may be a hard material that does not substantially deform when the rib 237 of the cylinder flange 231 abuts, or the rib 237 of the cylinder flange 231 abuts. It may be an elastic member that deforms elastically. The engaging member 176 may be provided interchangeably. The outer shape of the engaging member 176 is not particularly limited, but may be columnar, columnar, block-shaped, plate-shaped, or the like.

When the cylinder flange 231 (see FIGS. 6 and 7) is inserted in parallel into the receiving groove 175 of the syringe holder 170, the lower flange ribs 237 first come into contact with the engaging members 176, and then the cylinder flange 231 is further inserted. Is pushed downward, the engaging member 176 goes over the flange rib 237 and fits into the engaging recess 239 to engage. With such a configuration, the cylinder flange 231 can be held and fixed in the syringe holder 170.

The feel when the cylinder flange 231 is mounted in the receiving groove 175 depends on the amount of protrusion of the engaging member 176, the shape of the flange rib 237, the material of the engaging member 176, and the like. By separating the member constituting the syringe holder 170 and the engaging member 176 as in the present embodiment, the feel at the time of mounting can be appropriately set by selecting the material, for example. Further, the replaceable configuration has an advantage that the syringe holder 170 can be continuously used only by replacing the engaging member 176, for example, when the engaging member 176 is worn out.

The advantages of the oval syringe are as follows. That is, according to the configuration of the present embodiment in which the syringe is held in a posture in which the long axis of the ellipse is in the vertical direction, the width of the cylinder flange 170 in the horizontal direction is also increased by the reduction in the width of the syringe in the horizontal direction. Decrease. As a result, the width of the injection head in the horizontal direction can be reduced and the size of the injection head can be reduced. That is, since the width of the syringe is reduced as compared with the case where the syringe has a circular cross-sectional shape, the injection head can be miniaturized. In particular, in an injection head capable of mounting two or more syringes, the effect of miniaturization is great.

The above advantage, in other words, means that the size of the injection head is about the same as the conventional product, but a larger capacity syringe can be mounted. In recent years, for example, as a KVO (Keep Vein Open) function for the purpose of preventing the onset of thrombus, an injection method of continuing slow injection of a drug solution has been used, and the consumption of the drug solution tends to increase. Can also be seen. According to the configuration of the present embodiment, it is possible to cope with such a large-capacity chemical solution injection without causing an increase in the size of the injection head.

(B: Center frame)
As shown in FIGS. 1A and 1B, the injection head 110 of the present embodiment has a configuration in which the syringe holder 170 is supported by the center frame 181. The center frame 181 is located between the two ram members 133 of the piston drive mechanism 130, and is provided so as to extend in the front-rear direction of the injection head 110.

The center frame 181 may be made of any material and / or shape as long as it has sufficient rigidity so as not to interfere with the suction or injection of the chemical solution. In this embodiment, a flat plate-shaped member is used as an example. The center frame 181 which is a plate-shaped member is arranged in such a posture that the plate thickness direction is the left-right direction of FIG. 1A.

The material of the center frame 181 may be a resin material, a metal material, a carbon fiber material (CFRP carbon fiber reinforced plastic: Carbon Fiber Reinforced Plastics), or the like. In particular, a lightweight and highly rigid carbon fiber material is preferable because it is advantageous for reducing the size and weight of the injection head.

Referring to FIG. 1B, the rear end portion of the center frame 181 is fixed to a holding plate 183 provided so as to extend in the width direction of the injection head 110, and the center frame 181 and the holding plate 183 are substantially T-shaped. It constitutes a frame. A shaft plate 185 is further fixed to one end of the holding plate 183. The shaft plate 185 is a member for supporting the support shaft 116 (see FIG. 1A). The material of the holding plate 183 and the shaft plate 185 may be the same as that of the center frame 181, and may be a carbon fiber material as an example.

Although a plurality of members are used in the present embodiment, such as the center frame 181 and the holding plate 183, and the shaft plate 185, all of them may be formed as an integral member. Alternatively, the center frame 181 and the holding plate 183 may be an integral member, or the holding plate 183 and the shaft plate 185 may be an integral member. When a carbon fiber material is used, each member may be a laminate of carbon fiber materials, or may be an integral part by molding.

Refer to FIGS. 1A and 1B again, and one syringe holder 170 is attached to the tip of the center frame 181 so as to sandwich the center frame 181. Although not limited, the one syringe holder 170 and the other syringe holder 170 may be provided substantially symmetrically with the center frame 181 interposed therebetween.

As described above, according to the configuration in which the syringe holder 170 is supported by the center frame 181, it has the following effects. That is, as a configuration for supporting the syringe holder 170, for example, a structure in which support shafts (not shown) are provided on both sides of each ram member 133 and the syringe holder is supported by the two support shafts can be considered. However, according to the configuration in which the syringe holder 170 is held only by the center frame 181 provided between the ram members 133 without providing the support shafts on both sides as in the present embodiment, the size of the injection head 110 in the width direction can be increased. There is an advantage that the holding and injection head can be miniaturized.

Further, the ram member 133 is a member for pressing the piston members of the syringes 200A and 200B, and is usually arranged at a predetermined distance from each other. However, the center frame 181 of the present embodiment has a space thereof. Since it is provided in, the injection head does not become large. Even if the syringe holders 170 and 170 are supported only by the center frame 181 in this way, the chemical solution can be injected by using, for example, a carbon fiber material or designing the material into a shape that can secure sufficient rigidity. At this time, even when a pressing force is applied to the syringes 200A and 200B, the deformation of the member is suppressed, and the chemical solution can be satisfactorily injected.

Although one plate-shaped member is used for the center frame 181 in the present embodiment, the center frame may be composed of a plurality of members arranged between the ram members 133 and 133.

Subsequently, the specific structure of the piston drive mechanism 130 will be described with reference to FIG. 1B. In the present embodiment, the motor 131, which is an ultrasonic motor, the transmission mechanism 132, and the ram member 133 are arranged in order from the rear end to the front end of the injection head 110. More specifically, the transmission mechanism 132 has a base module 132-1 provided adjacent to the motor 131, and a cylinder module 132-2 arranged in front of the base module 132-1. The whole is modular.

In this example, the base module 132-1 has a substantially cylindrical casing, and a gear (not shown) for transmitting the output from the shaft of the motor 131 is provided inside the casing. The cylinder module 132-2 also has a substantially cylindrical casing, and a linear motion mechanism or the like (not shown) for moving the ram member 131 forward and backward is provided inside the casing. The casing of the cylinder module 132-2 may be connected and fixed to the holding plate 183.

The rod-shaped ram member 133 is arranged so as to extend toward the front end side of the injection head 110 through the holding plate 183. The base end side (not shown) of the ram member 133 is held in the cylinder module 132-2, and the presser member 135 is provided on the tip end side of the ram member 133. As an example, the ram member 133 may be arranged coaxially with the casing of the cylinder module 132-2.

Although not limited, the board module 115'may be arranged between two cylinder modules 132-2 arranged adjacent to each other. A control circuit 115 (see FIG. 2) and the like are housed in the board module 115'.

According to the above configuration, since the piston drive mechanism 130 is modularized, it is easy to deal with a failure, for example, and it is excellent in maintainability. Further, for example, even when the chemical solution is injected from three or more syringes, the piston drive mechanism 130 can be easily added.

(C: Flange gripping mechanism)
The flange gripping mechanism 140 of the present embodiment will be described with reference to FIGS. 12 to 18. FIG. 12 is a perspective view showing a presser member 135 provided at the tip end portion of the ram member 133 and a flange gripping mechanism 140 provided at the front end portion thereof. The flange gripping mechanism 140 may be different between the A side and the B side of the injection head, but this embodiment has a common configuration. Hereinafter, the flange gripping mechanism 140 on the B side will be described as an example. Therefore, the description is about the member related to the syringe 200B, but of course, the following items also apply to the mechanism on the A side.

The flange gripping mechanism 140 grips the piston flange 241 of the syringe 200B by advancing the ram member 133 with the syringe 200B set in the syringe holder 170, for example. Therefore, strictly speaking, the syringe 200B is not moved with respect to the flange gripping mechanism 140 on the fixed side, but in the following, in order to make the explanation easier to understand, "push the piston flange into the pair of rotating claws". The expression such as is also used.

As shown in FIG. 12, the presser member 135 is a member for pressing the piston member of the syringe, and in this example, it has a flat pressing surface 135a. Although not shown in FIG. 12, a load cell or the like for detecting the pressure pressing the piston member may be provided inside the presser member 135. Further, a predetermined sensor (not shown) configured to move together with the presser member 135 is provided in the vicinity of the presser member 135, and the position of the presser member 135 and the piston member using the sensor is provided. Relationships may be detected. Specifically, it may detect that the presser member 135 is close to the piston member. As the predetermined sensor, various sensors such as a physical sensor, an optical sensor, a magnetic sensor, a contact type, and a non-contact type can be used. Although not limited to, an optical object detection sensor having a light emitting portion and a light receiving portion disclosed in Japanese Patent No. 6422939 may be used.

As shown in FIGS. 12 and 13, the flange gripping mechanism 140 has a pair of left and right rotary claws 143, and the pair of rotary claws 143 is for gripping the piston flange 241 from both sides. The detailed operation will be described later (see FIG. 18), but the rotary claw 143 is configured to be rotatable around a shaft 149 extending in a direction parallel to the ram member 133. Specifically, as shown in FIG. 18, all the rotary claws 143 rotate in the same direction (clockwise in this example) around the shaft 149, whereby when gripping the piston flange 241, the piston flange 241 is gripped. One rotating claw 143 (right side in the drawing) is configured to rotate upward, and the other rotating claw 143 (left side in the drawing) is configured to rotate downward. In the present invention, the direction of rotation is not particularly limited as long as each rotating claw 143 operates in a complex manner in the vertical direction. The rotation direction of the rotary claw 143 may be counterclockwise around the axis 149 instead of clockwise.

Explaining the rotary claw 143 and its peripheral structure in detail, first, as shown in FIG. 14, the rotary claw 143 is projected from the base portion 146 rotatably supported by the shaft 149 and the base portion 146. It has a formed claw portion 145. In this example, the pair of rotating claws 143 are arranged so that the claw portions 145 face each other.

The claw portion 145 is a substantially plate-shaped portion as a whole, and when the piston flange 241 is pushed in, a tapered surface 145s that abuts on the outer peripheral portion of the piston flange 241 is formed. The reason for forming such a tapered surface 145s is that when the outer peripheral portion of the piston flange 241 is pressed against the same surface, a circumferential force for rotating the rotary claw 143 around the shaft 149 is generated. This is to make it. The rotary claw 143 rotates due to the moment generated by this force.

The principle of rotation of the rotary claw 143 is that, as shown in FIG. 15, when the piston flange 241 is linearly moved in the direction of arrow a, a part of the outer peripheral portion thereof is tapered. This is because the component force of the force that abuts on a part of the 145s and the piston flange 241 presses the tapered surface 145s acts as a circumferential force around the shaft 149. As the piston flange 241 is pushed in, the rotary claw 143 gradually rotates while the outer peripheral portion of the piston flange 241 and the tapered surface 145s slide. If such a principle is used, the specific shape and size of the tapered surface 145s can be changed as appropriate.

In the present embodiment, as shown in FIG. 15, the tapered surface 145s is three-dimensionally inclined with respect to the arrow a direction (the normal direction of the tapered surface 145s and the arrow a direction intersect three-dimensionally). Is formed in. The size of the tapered surface 145s may be appropriately set according to the size and shape of the piston flange 241 that is expected to be used.

In the present embodiment, as shown in FIG. 16, by providing the tapered surface 145s in a relatively wide range, it is possible to contact the outer peripheral portion of the piston flange 241'of a relatively small size, and the piston of a relatively large size is provided. The outer peripheral portion of the flange 241 ″ can also be brought into contact with the outer peripheral portion. According to such a configuration, it is possible to support not only a single size but also a plurality of sizes of piston flanges.

The material of the rotary claw 143 is not particularly limited, such as a metal material, a resin material, and a carbon fiber material, but a metal material may be used as an example.

With reference to FIGS. 13 and 14 again, the rear surface 145t of the claw portion 145 is a surface facing the front surface of the piston flange 241. Therefore, the rear surface 145t may be a flat surface parallel to the front surface of the piston flange 241. As shown in FIG. 14B, the corner portions 145a and 145a of the claw portion 145 may be formed in a gently curved rounded shape.

As shown in FIGS. 14B and 16, the initial position of the pair of rotating claws 143 is such that the claw portion 145 of each rotating claw 143 extends toward the center O. In this initial state, an urging force around the shaft 149 is applied by an urging means (not shown), whereby the posture in the initial state is maintained. The urging means may be, but is not limited to, a coil spring (torsion spring) passed through the shaft 149. If the urging force by the coil spring is too strong, the rotary claw 143 will not rotate well when the piston flange 241 presses against the tapered surface 145s, and if it is too weak, the rotary claw 241 will rotate when it enters between the rotary claws 143. Since the claw 143 may not return to the initial position and the flange may not be gripped well, it is preferable to appropriately set the claw 143 and the piston flange 241 in consideration of the material and shape. Various other means can be used as the urging means, and a leaf spring or the like may be used.

In the present embodiment, as shown in FIG. 17, the above-mentioned rotating claw 143 may be further provided at the tip portions of the pair of arms 141. A pair of arms 141 are provided on both sides of the presser member 135. Each of the arms 141 is rotatably supported by a shaft 141a, whereby the pair of arms 141 can be expanded and closed in the radial direction of the piston flange 241. An urging force around the shaft 141a is applied to each arm 141 by an urging means (not shown), whereby the closed state is maintained. As the urging means, a coil spring (torsion spring) passed through the shaft 141a may be used. As described above, the urging means is also used for the rotation of the rotary claw 143 around the shaft 149, but the urging force of the urging means is the operation of opening the arm 141 and the rotation of the rotary claw 143. It is desirable that the latter operation is set to occur preferentially among the operations to be performed.

<Operation>
The operation of the flange gripping mechanism described above will be described below.

First, with the ram member 133 of the piston drive mechanism 130 retracted, the syringe 200B in a state where the chemical solution is contained or in an empty state is attached to the syringe holder 170. Mounting is performed by moving the syringe 200B linearly with respect to the syringe holder 170 so that the piston flange 231 of the syringe 200B is inserted into the receiving groove 175 of the syringe holder 170 (see "downward" direction in FIG. 1A).

When the syringe 200B is attached to the syringe holder 170, for example, the physical button 161 of the injection head 110 is operated to advance the ram member 133 as shown in FIG. 19 (a). When the ram member 133 advances to a certain position, the outer peripheral portion of the piston flange 241 comes into contact with the tapered surface 145s of each rotary claw 143.

When the ram member 133 is further advanced in this state, as described with reference to FIG. 18, the rotary claw 143 is pushed by the piston flange 241, so that each rotary claw 143 rotates around the shaft 149. The nails gradually open. Then, when the pair of rotary claws 143 are opened to the extent that the piston flange 241 can pass between them, the piston flange 241 is inserted between the pair of rotary claws 143 as shown in FIG. 19B, and at the same time, the shaft 149 is inserted. The rotating claw 143 returns to its original position due to the restoring force of the surrounding urging means, so that the piston flange 241 is gripped by the pair of rotating claws 143. The series of gripping operations can be performed without expanding the pair of arms 141, but from the viewpoint of smooth insertion and the like, the pair of arms 141 are expanded and the piston flange 241 is between the pair of rotating claws 143. It may be accepted (combined use of rotation of each claw and expansion of a pair of arms).

As described above, according to the flange gripping mechanism 140 of the present embodiment, a part of the piston member can be gripped only by bringing the gripping mechanism linearly close to the piston member, which is a complicated work by the operator. Does not need. Further, since the rotary claw 143 can grip piston flanges of various sizes as described above, it is not necessary to prepare a plurality of flange gripping mechanisms 140 for use depending on the size of the piston flange used.

According to the present invention, when gripping the piston flange 241, one rotating claw 143 and the other rotating claw 143 perform a line-symmetrical operation with reference to the vertical center line L1 (see FIG. 16) (that is,). In the example of FIG. 16, for example, both rotating claws 143 may be rotated so as to be lifted upward), but as shown in FIG. 16 and the like, in the present embodiment, they are point-symmetrical. It works in the opposite direction. According to such a configuration, the force applied to the piston flange 241 becomes symmetrical, so that the rotary claw 143 can be operated satisfactorily.

In the above-described embodiment, a pair of rotating claws 143 are used, but as a modification, for example, a plurality of configurations of three or more are assumed. Further, such a flange gripping mechanism is not necessarily limited to one used as a part of an injection device, and may be used in various devices (for example, a chemical aspirator) having a function of gripping a flange of a syringe. ..

(Syringe adapter)
Next, a specific example of the adapter 270 holding the syringe 200A filled with the contrast medium will be described with reference to FIGS. 20 and 21.

For example, when injecting a contrast medium in a CT examination, a syringe 200A having the same size as the saline syringe 200B may be used. In this case, both the first and second syringes are directly directed to the syringe holder 170. You just have to put it on. However, in the case of MRI examination and the like, a relatively small syringe may be used because a small amount of contrast medium is required. In order to deal with such a case, in the present embodiment, the syringe 200A can be attached to the syringe holder 170 via the cylinder adapter 270.

As shown in FIGS. 20 and 21, the syringe adapter 270 has a cylinder holding portion 273 that receives the cylinder member 210 of the syringe 200A and a flange holding portion 271 that receives the cylinder flange 211. The cylinder adapter 270 is provided so as to be rotated by an operator, and has, for example, a stopper arm 277 that presses the set syringe from above. The cylinder holding portion 273 has a recess 273a curved in a substantially U shape so as to have an inner surface shape complementary to the outer shape of the cylinder member 210. The flange holding portion 271 has a receiving groove 271a for receiving the cylinder flange 211.

The outer shape of the flange holding portion 271 may be partially the same as that of the cylinder flange 231 of the syringe 200B described with reference to FIGS. 6 and 7. That is, the flange holding portion 271 may have an inverted egg-shaped contour shape (more accurately, a shape substantially half of the lower side of the inverted egg-shaped contour shape) as in the cylinder flange 231 as an example. A U-shaped recess 272 is formed on the rear surface on which the piston member 220 of the syringe is located when the syringe is set.

As shown in FIG. 21, a thick portion 286, a rib 287, and an engaging recess 289 are formed around the recess 272. The rib 287 extends horizontally from the thick portion 286 to the left and right, and an engaging recess 289 is formed above the rib 287. The engaging recess 289 functions in common with the engaging recess 239 of the syringe 200B described with reference to FIG. 7, and when the syringe adapter 270 is set in the syringe holder 170, the engaging member 176 becomes the engaging recess 289. It is designed to fit into and engage with.

The cylinder adapter 270 configured as described above can be set in the syringe holder 170 in the same procedure as the procedure for mounting the syringe 200B or the like.

Regarding the elliptical syringe, not only the syringe on the B side but also the syringe on the A side may be an elliptical syringe. Further, the shape is not necessarily limited to a strict elliptical shape, and any non-circular shape having a different length between the long axis and the short axis of the cross-sectional shape may be adopted. With respect to one or both of the syringes 200A and 200B, the chemical solution may be sucked from the storage container containing the chemical solution as needed and used a plurality of times.

In the above embodiment, the operation in which the piston flange is gripped by the pair of rotating claws by moving the piston member in the direction of its axis has been described. However, as another gripping method, the piston member may be moved in a direction orthogonal to the axis thereof to grip the piston flange between the pair of rotating claws, as in the mounting procedure in the so-called side loading method.

Although one embodiment of the present invention has been specifically described above with reference to the drawings, the present invention is not limited to the specific configuration described above. Hereinafter, some peripheral devices and the like used together with the injection head will be described.

(P1. Stand and display)
The injection head 110 may be held by a movable holding stand 103 as shown in FIG. The holding stand 103 has a base portion having a plurality of casters and a support column supported by the base portion. The injection head 110 is rotatably held on the upper end side of the column.

A display 151-1 may be attached to the holding stand 103. The display 151-1 may be connected to the injection head 110 and / or the console 150 to display various information regarding the chemical injection. Regarding the holding of the display 151-1. Specifically, as shown in FIG. 23, the display 151-1 may be held by the height-adjustable holding bar 103a.

The holding stand 103 may also be provided with a container holder 104 for holding a container such as a bottle containing a chemical solution. The container holder 104 can hold, but is not limited to, a container containing the chemical solution sucked into the first syringe 200A and a container containing the chemical solution sucked into the second syringe 200B. It may have two holding portions 105-1 and 105-2.

The equipment and the like shown in FIGS. 22 and 23 are also preferably made of a non-magnetic material when used in an MRI inspection. Alternatively, the device may be operated only at a timing that does not affect the inspection.

Since the injection head 110 of one form of the present invention can be configured to be compact and lightweight, it can be satisfactorily held by a ceiling-hung type holding device in addition to the stand as shown in FIG.

The control using the head display 151-1 may be as follows, for example:
-The operator can input and / or change the injection protocol via the head display 151-1, and the drug solution injection operation or the like is performed based on the input and / or change. The injection protocol in this case may be for the main injection or for a test shot.
-The injection protocol set by another device (for example, a console) is displayed on the head display 151-1 so that the operator can check the contents.
-The chemical solution injection device is operated by a predetermined input to the head display 151-1. The predetermined input may be touch panel input, physical button pressing, voice input, or the like. The operation of the drug solution injection device may be start, pause, restart, end, or the like of the drug solution injection.
-The head display 151-1 shows not only predetermined information before the start of drug solution injection (for example, information on the injection protocol) but also predetermined information during drug solution injection (syringe remaining amount, injection amount, injection rate, injection pressure, progress). One or more selected from the time and the like may be displayed.

According to the configuration of one embodiment of the present invention, it is possible to carry out the test on the display beside the injection head. Therefore, the operator should look at the needle stick of the patient to confirm that there is no leakage of the drug solution, or if the leakage is confirmed, or if the patient becomes ill, the operation should be stopped immediately. It is possible to carry out safe chemical injection.

(P2. Console)
As for the console 150 used together with the injection head 110, various ones can be used depending on the use of the chemical injection device, but as an example, the one shown in FIG. 24 may be used. The console 150 is a stationary type that is used by being placed on a desk or the like, and is provided with a display 151, a switch 157, and the like. It may be a touch panel type display. The shape of the housing 158 of the console 150 is not particularly limited, but it may be a highly stable design in which the width is relatively wide with respect to the height.

(P3. Example of appearance of injection head)
More specifically, the injection head 110 may have an appearance as shown in FIGS. 25 to 33. The present specification also discloses the design of the injection head shown in FIGS. 25 to 33. In addition to the overall design of the injection head, for example, a partial design in which the following parts are symmetrical is also disclosed: the shape of the syringe holder, the flange gripping mechanism, the center frame, the housing, the physical button, and / or Arrangement etc.

Description of the article: This article is an injector for a drug solution injector for holding a syringe filled with a drug solution such as a contrast medium and injecting the drug solution in the syringe toward a patient. By advancing the ram member with the syringe set, the piston in the syringe is pushed and the chemical solution is pushed out. The operation buttons arranged on the upper surface of the article are for operating the forward, backward, stop, etc. of the ram member.

(P4. Syringe)
In one embodiment of the present invention, syringes having the shapes shown in FIGS. 34 to 38 may be used. In these drawings, a code (with the letter M) corresponding to the code representing each part of the syringe 200B described above is used, but duplicate description will be omitted. The syringe M200 of FIG. 34 includes a cylinder member M230 having a substantially elliptical cylinder shape and a piston member M240 inserted therein. Flange M231 and M241 are formed at the rear ends of the cylinder member M230 and the piston member 240M, respectively.

The contour shape of the cylinder flange M231 may be vertically symmetrical, but in this example, it is an asymmetrical shape. An uneven portion of an arrow mark may be formed near the lower end of the cylinder flange M231, and a character such as "SET" may be formed on the upper surface side. As in this example, the piston member M240 may have a structure in which a plurality of reinforcing ribs are formed to give strength.

The gasket M245 is not limited, but may be an elastic body formed in the shape shown in FIG. 36, and is attached to the tip end portion of the piston member M240. The cylinder member M230 may have the shape shown in FIG. 37 as an example, and the conduit portion formed at the tip portion thereof may be provided in any shape. Although not limited to this, it may be a conduit portion M233 as shown in FIG. 38 (a) or a conduit portion M233'as shown in FIG. 38 (b).

(P5-1. Rodless syringe and corresponding drive mechanism)
As described above, a so-called rodless type syringe may be used in one embodiment of the present invention. Specifically, a syringe and a piston drive mechanism having a structure as shown in FIGS. 39 to 41 are used. You may. Hereinafter, the connection structure of the ram 1110 and the gasket 1100 will be described with reference to these figures. Here, the ram 1110 is a part that moves linearly forward and backward along the axial direction as a part of the piston drive mechanism, and the gasket 1100 is a part that is inserted into the cylinder 1091 which is the outer cylinder of the syringe 1090. is there.

In the examples of FIGS. 39 to 41, the cylinder 1091 has a cylindrical shape, and the gasket 1100 inserted therein has a circular contour shape and a hole H having an enlarged inlet diameter. That is, in the hole H, the inlet into which the ram 1110 is inserted has a longer inner diameter than the bottom pressed by the end face of the ram 1110. Gasket 1100 also has a plurality of engaging claws 1122, which are configured to displace between an expanded position (FIG. 40) and a constricted position (FIG. 41). There is. The engaging claw 1122 includes an inner surface S1 including a first inner surface 1126 and a second inner surface 1127 that define the hole H, and an outer surface S2 that is inclined away from the perpendicular line P passing through the center of the hole H (bottom). There is. An O-ring 1130 is fitted on the outer surface S2. The first inner surface 1126 extends in a ring shape from the bottom of the hole H with which the end surface of the front end portion 1111 of the ram 1110 abuts. The first inner surface 1126 extends parallel to the perpendicular line P. The second inner surface 1127 extends in a ring shape from the first inner surface 1126 to the protrusion 1124. Further, the second inner surface 1127 is inclined with respect to the first inner surface 1126 in a direction away from the perpendicular line P as it approaches the entrance of the hole H.

The outer surface S2 of the engaging claw 1122 is inclined so as to move away from the perpendicular line P as it approaches the entrance of the hole H. Therefore, the length of the line segment that intersects the perpendicular line P and connects the outer edges of the plurality of engaging claws 1122 is longer than the length of the inner diameter of the cylinder 1091. That is, the outer edge of the engaging claw 1122 is located radially outside the inner surface of the cylinder 1091. The engaging claw 1122 has a protrusion 1124 that projects toward the perpendicular P.

The ram 1110 is formed with an annular engaging groove 1112 to which the protrusion 1124 is engaged. When the protrusion 1124 of the engaging claw 1122 displaced to the narrowed position is not arranged in an annular shape, the engaging groove 1112 may be formed at a position corresponding to the protrusion 1124. In the front end portion 1111 of the ram 1110, the outer surface of the portion on the end face side of the engaging groove 1112 is also slightly inclined with respect to the central axis R of the ram 1110. The inclination angle of the outer surface with respect to the central axis R (for example, 1 to 5 degrees) is preferably set smaller than the inclination angle of the second inner surface 1127 with respect to the perpendicular line P (for example, 4 to 10 degrees). Since the outer surface of the front end portion 1111 is inclined, the front end portion 1111 can be guided into the hole H so that the central axis R is aligned with the vertical line P when the front end portion 1111 is inserted.

When the ram 1110 is inserted into the hole H until the state shown in FIG. 40, the end surface (tip surface) of the front end portion 1111 comes into contact with the bottom of the hole H. At this time, the engaging claw 1122 is in the expanded position, and the outer surface of the front end portion 1111 comes into contact with the boundary portion (connecting portion between the surfaces) between the first inner surface 1126 and the second inner surface 1127 of the engaging claw 1122. In other words, the inner dimension of the hole H is set to a size that abuts on the outer surface of the front end portion 1111 at the boundary portion. An annular groove 1125, which is a starting point of deformation of the engaging claw 1122, is formed at a position corresponding to the boundary portion. The annular groove 1125 has, but is not limited to, a shape having a substantially semicircular cross section. The boundary portion is set at a position corresponding to the center of the bottom of the annular groove 1125. That is, the center and the boundary portion of the bottom of the annular groove 1125 are provided so as to be located in the same cross section orthogonal to the longitudinal direction in this example. The inner surface S1 is formed so as to be inclined with respect to the boundary portion, and therefore, when the front end portion 1111 is inserted, a gap is formed between the outer surface of the front end portion 1111 and the second inner surface 1127. On the other hand, since the outer surface of the front end portion 1111 is also slightly inclined, a gap is also formed between the outer surface and the first inner surface 1126. The annular groove 1125 may have a substantially trapezoidal shape or a substantially triangular cross-sectional shape so as to narrow inward.

When the ram 1110 pushes the gasket 1100, the gasket 1100 advances in the cylinder 1091. When the gasket 1100 advances, the outer surface S2 (FIG. 39) of the engaging claw 1122 is inclined, so that the outer surface S2 of the engaging claw 1122 comes into contact with the inner surface of the cylinder 1091. Then, as the cylinder 1091 moves forward, the engaging claw 1122 is displaced toward the perpendicular line P side due to the reaction force from the inner surface of the cylinder 1091. At this time, the engaging claw 1122 is deformed starting from the center of the bottom of the annular groove 1125. Therefore, the boundary portion between the first inner surface 1126 and the second inner surface 1127 is pressed against the front end portion 1111.

That is, the boundary portion between the first inner surface 1126 and the second inner surface 1127 is displaced toward the perpendicular line P of the sucker. As a result, even if the front end portion 1111 is inserted at a position biased with respect to the perpendicular line P in the hole H, the front end portion 1111 is displaced so that the position of the central axis R of the front end portion 1111 is aligned with the perpendicular line P. .. That is, the front end portion 1111 is pushed by the boundary portion B and displaced toward the center of the hole H. Therefore, it is possible to prevent the central axis R from tilting with respect to the gasket 1100. Further, even if there is a gap between the front end portion 1111 and the suction hole H due to manufacturing tolerance or the like, the front end portion 1111 is held at the boundary portion. As a result, it is possible to prevent the ram 1110 from rattling with respect to the gasket 1100.

When the gasket 1100 is inserted into the cylinder 1091 until the state shown in FIG. 41, the engaging claw 1122 is narrowed by receiving the reaction force from the inner surface of the cylinder 1091. Then, the protrusion 1124 of the engaging claw 1122 penetrates into the engaging groove 1112, and the protrusion 1124 engages with the engaging groove 1112. As a result, the gasket 1100 and the ram 1110 are mechanically connected. With the displacement of the engaging claw 1122, the annular groove 1125 is deformed so as to expand. After that, when the gasket 1100 advances in the cylinder 1091, the sealing member 1140 presses the chemical solution in the cylinder 1091. As a result, the chemical solution is pushed out from the tip of the syringe.

After injecting the chemical solution, the ram 1110 retracts, and the gasket 1100 connected to the ram 1110 also retracts. Then, when the ram 1110 and the gasket 1100 are retracted to the positions shown in FIG. 40, the restriction by the inner surface of the cylinder 1091 is released, the engaging claw 1122 expands outward, and the connection between the engaging claw 1122 and the ram 1110 is released. To.

According to the ram 1110 and the gasket 1100 as described above, the engaging claw 1122 is deformed starting from the center of the bottom of the annular groove 1125. Therefore, the plurality of engaging claws 1122 are evenly displaced toward the perpendicular line P. Further, since the front end portion 1111 is held at the boundary portion between the first inner surface 1126 and the second inner surface 1127, the position of the central axis R of the front end portion 1111 of the ram 1110 is aligned with the perpendicular line P. As a result, when the ram 1110 is detached from the gasket 1100, it is possible to prevent the front end portion 1111 from being positioned at a position biased with respect to the perpendicular line P. Therefore, it is possible to prevent the engaging groove 1112 of the front end portion 1111 from being caught in the protrusion 1124. Further, when connecting the gasket 1100 and the ram 1110, it is possible to prevent the ram 1110 from rattling with respect to the gasket 1100. Further, since the gasket 1100 and the ram 1110 are directly connected, the distance between the syringe 1090 and the pressing portion (piston drive mechanism) can be shortened. Therefore, the size of the injection head can be reduced.

The ram 1110 may be made of, for example, stainless steel or aluminum, and as a specific example, it may be manufactured by welding a solid substantially cylindrical front end portion to a hollow pipe. Alternatively, it may be manufactured by screwing a solid front end into a hollow pipe. The front end may be made of a material other than stainless steel or aluminum, for example a material having a higher hardness than the gasket.

(P5-2. Rodless syringe and other examples of corresponding drive mechanism)
Although the example in which the gasket 1100 having a circular contour shape is inserted into the cylindrical cylinder 1091 has been described above, in one embodiment of the present invention, such a characteristic structure is further applied to the elliptical cylinder. It may be the one that has been done. Hereinafter, a brief description will be given with reference to FIG. 42.

In the example of FIG. 42, an elliptical syringe 2090 is drawn, and this syringe 2090 has a cylinder 2091 having a flange formed on the rear end side and a gasket 2100. The outer surface of the gasket 2100 inserted into the cylinder 2091 comes into contact with the inner surface of the cylinder 2091. The gasket 2100 engages with the front end portion 1111 of the ram 1110, and is moved back and forth in the cylinder 2091 by the ram 1110.

The gasket 2100 has a sealing member 2140 as a tip portion having an elliptical cross-sectional shape. In the cross section of the seal member 2140, the length in the height direction is longer than the length in the width direction orthogonal to the height direction. Further, the gasket 2100 includes a sucker 2120 having a plurality of divided engaging claws 2122, and the tip of the sucker 2120 is inserted into the sealing member 2140. The sucker 2120 is made of an elastic resin such as POM (polyacetal resin), and can be manufactured by molding. The sealing member 2140 is made of, for example, butyl rubber and can be manufactured by molding.

Regarding the operation of the gasket 2100, when the motor (not shown) of the piston drive mechanism rotates with the engaging claw 2122 connected to the ram 1110, the ram 1110 and the gasket 2100 move forward. The engaging claw 2122 may be provided with a groove into which the O-ring is fitted, and the expansion of the engaging claw 2122 can be restricted by fitting the O-ring. The cylinder 2091 has a cross-sectional shape complementary to that of the gasket 2100. That is, the cylinder 2091 has a substantially elliptical cross-sectional shape, and the length in the height direction in the cross section is longer than the length in the width direction orthogonal to the height direction. Even when such an elliptical syringe is used, the connection structure as described with reference to FIGS. 39 to 41 can be used, and the same advantages as those described above using the circular syringe as an example can be obtained. Obtainable.

Note that, in FIG. 42, what is indicated by reference numeral 2095 on the rear surface of the flange of the cylinder 2091 is a protrusion formed so as to protrude from the same surface. By forming the two protrusions 2095 at a predetermined distance above and below in this way, a recess is formed between the protrusions, and a predetermined engagement for positioning and / or fixing the cylinder 2091 in the recess. The parts are designed to engage. The engaging portion may be a structural portion provided as a part of the injection head, or may be a structural portion provided as a part of the adapter.

(P6. Control of prefilled syringe by piston drive mechanism)
As the syringe set in the device for automatically injecting the drug solution, a prefilled syringe pre-filled with the drug solution (for example, a contrast medium) is often used. In the case of a prefilled syringe, the gasket of the syringe and the ram of the piston drive mechanism do not necessarily have to be mechanically connected (connected) because it is generally not necessary to suck the chemical solution into the syringe in the hospital facility. As an example, see FIGS. 39 to 42).

Even in such a case, a piston drive mechanism having a substantially cylindrical rod-shaped ram 1110 as shown in FIGS. 39 to 42 is used to advance the ram 1110 and push the gasket (not shown) of the prefilled syringe. You may do so and inject the drug solution.

(P7. Syringe mounted on the front loading type injection head via an adapter)
The injection head shown in FIG. 1A has a configuration in which the syringe holder 170 is held on the tip end side of the center frame 181. However, as shown in FIG. 43, a so-called front loading type injection head can also be used. The injection head P110 has a housing P111 in which a piston drive mechanism (not shown) and the like are housed therein, and a syringe holder P170 is provided at a front end portion thereof. The syringe holder P170 is configured to hold the elliptical rodless syringes P200A and P200B, and specifically, has a substantially U-shaped receiving groove for receiving the cylinder flange P231 of the cylinder member P230. There is. The cylinder flange P231 itself may have an elliptical shape, or may have a substantially egg shape as described above.

In such an injection head P110, the contrast agent syringe may be configured to hold the prefilled syringe 200 via the adapter P270 as shown in FIG. 44 instead of the syringe P200A. Similar to the one illustrated in FIG. 3, the prefilled syringe 200 has a long piston member 220 inserted into a cylindrical cylinder member 210, and a piston flange 221 is formed at the rear end of the piston member 220. There is. Although not limited, the piston plunge 221 has a circular contour and a flat rear surface.

The adapter P270 has a shape like a cylinder divided in half as a whole, and the prefilled syringe 200 is set so as to be placed on the adapter from above in the drawing. In this example, the adapter P270 is provided with a length that holds the piston member 220 pulled out from the cylinder member 210 and a part of the cylinder member 210, as shown in the figure. A holding groove P277 is formed in a part of the adapter P270 to hold the cylinder flange 211 of the prefilled syringe 200 directly or via the adapter. The rear end of the adapter P270 is provided with an elliptical or substantially egg-shaped contoured adapter flange P271 corresponding to the syringe holder P170 of the injection head. The adapter P270 is held by fitting the adapter flange P271 into the receiving groove of the syringe holder P170. By using such an adapter P270, the contrast medium prefilled syringe conventionally used in hospital facilities can be satisfactorily used in the injection head P110 holding the elliptical type syringe P200A.

It should be noted that a predetermined identification means may be provided so that the type of the adapter P270 as described above can be recognized. Such identification means may be applied not to the adapter P270 of FIG. 44 but to the adapter 270 shown in FIGS. 20, 21 and the like. For example, the physical shape of the adapter may be read by a predetermined sensor or a contact-type switch (provided on the injection head side in one example) to recognize the type of the adapter. Alternatively, the adapter may be provided with a data storage medium, which may be read by a predetermined reading device (provided on the injection head side in one example) to recognize the type of the adapter. Further, a magnet or the like may be provided on the adapter, and the type of the adapter may be recognized by detecting the magnet or the like with a hall sensor. The device for identifying / detecting the adapter is not particularly limited, and a proximity sensor or the like may be used. The information to be recognized is not particularly limited, and in addition to the information about the adapter, for example, information about the syringe held in it (information about the syringe itself and / or information about the drug solution contained therein). You may. Using such an identification means, the speed may be set according to the size of the syringe, the injection amount may be set, and / or the movement range (front-back limit) of the piston (plunger) may be set.

Although not limited, in one embodiment of the present invention, as in the injection head P110 of FIG. 43, a switching mechanism P615 for switching a part of the opening / closing state of the chemical solution circuit may be further provided. The switching mechanism P615 may be an on-off valve that operates using a predetermined actuator (not shown) as a drive source, or a clamp mechanism that closes the chemical solution circuit by sandwiching the tube. In the case of an injection head for MRI, it is preferable to use a non-magnetic ultrasonic motor as an actuator of the switching mechanism, which can be used without any trouble even in a high magnetic field environment of the MRI apparatus. Further, such a switching mechanism P615 may be held by, for example, an arm P601 extending from the housing P111 side. Alternatively, it may be held in a device separate from the injection head. The ultrasonic motor is characterized in that the holding torque is high (even when not controlled) as compared with other motors such as a DC motor and a brushless motor. A dedicated brake mechanism or the like may be provided to keep the chemical solution circuit in a closed state (example), but in the case of a configuration using an ultrasonic motor, the position is fixed by the holding force of the ultrasonic motor itself. , The brake mechanism may be omitted.

(P8. Use of different types of syringes and corresponding chemical solution circuits)
In one embodiment of the invention, the injection head does not necessarily hold a plurality of syringes of the same shape and / or size, but may hold different types of syringes by their respective piston drive mechanisms. A specific example will be described with reference to FIG. 45. In the example of FIG. 45, the injection head comprises a type of piston drive mechanism having a ram 1110 as shown in FIGS. 39-42. That is, in this embodiment, the ram 1110 does not have a claw member that grips the piston flange of the syringe. Therefore, if the syringe uses the gasket 1100 having a special structure as shown in FIGS. 39 to 42, the connection between the ram 1110 and the gasket 1100 is achieved (as a result, the gasket 1100 can be moved backward). Otherwise, the connection between the ram 1110 and the gasket will not be achieved.

In FIG. 45, the contrast medium side is a general syringe 200A, and the physiological saline side is a syringe 1090 using the gasket 1100 having a special structure. In the case of such a configuration, since the piston member of the syringe 200A is not connected and held by the piston drive mechanism (ram), the following problems may occur.

Explaining the configuration of FIG. 45 as a premise, here, a Y-shaped chemical solution circuit 900 is connected to each syringe 200A and 1090. In the chemical solution circuit 900, the flow path 911 from the syringe 200A and the flow path 912 from the syringe 1090 merge and continue to one flow path 913, and an injection needle or the like is placed on the end side of the flow path 913 (not shown). Be connected. A mixing device (mixing connector) may be provided at the confluence of the flow path 911 and the flow path 912 to generate a spiral flow in the device and thereby efficiently mix a plurality of chemicals. In the embodiment of FIG. 45, opening / closing valves V-1 to V-3 are arranged in the flow paths 911 to 913, respectively. The on-off valves V-1 to V-3 may be any as long as they can switch the opening and closing of the flow path. The on-off valves V-1 to V-3 preferably have a structure that can be automatically switched by a switching mechanism provided as a part of the injection head or a switching mechanism provided as an accessory of the injection head. A part or all of the on-off valve may be replaced with a one-sided valve, or a clamp mechanism or the like may be used. Not all of the on-off valves V-1 to V-3 are indispensable, and one of them or two of any combination may be provided.

In such a chemical solution circuit 900, when the opening / closing valve is not provided, if the ram 1110 on the syringe 1090 side is pulled to suck the chemical solution into the syringe, the pressure inside the syringe 1090 becomes negative, and the pressure is increased accordingly. The chemical solution in the other syringe 200A connected to the syringe via the chemical solution circuit 900 may be sucked out to the chemical solution circuit 900 side. Therefore, in this case, it is preferable in one embodiment to control the opening / closing valve V-1 to be automatically closed when the operation is performed. As a result, it is possible to prevent unintentional wraparound of the chemical solution.

Even when the suction operation as described above is not performed, for example, when the posture of the injection head is changed for injection of the chemical solution (specifically, the posture in which the tip side of the syringe is lower than the end side), the chemical solution is used. Due to its own weight, the chemical solution may flow unintentionally in the chemical solution circuit. In order to prevent this, at least one of the on-off valves V-1 to V-3 (specifically, for example, the valve V-1 for preventing the outflow of the chemical solution from the syringe on the side where the piston member is not held) and / Or controlling the V-3) to close automatically is also preferred in one embodiment. In addition, in order to prevent the chemical solution mixed with blood etc. on the subject side from flowing back to the upstream side of the chemical solution circuit, close the on-off valve V-3 or regulate the flow with a one-sided valve. It may be. Regarding the opening / closing valve V-2, if the volumes of the syringe 200A and the syringe 1090 are significantly different, the chemical solution may sneak into the other side (syringe 1090 side) during injection with the syringe 200A, so that the other side is opened / closed during injection. It is also preferable to control the valve V-2 so as to close it. When injecting the syringe on the larger capacity side, the on-off valve on the other side may be closed.

The above-mentioned unintended wraparound of the drug solution (movement of the drug solution from the syringe 200A side to the syringe 1090 side) occurs more prominently when the size of the syringe 200A is relatively small and the size of the syringe 1090 is relatively large. In other words, the operation control as described above is particularly preferably available when the capacity of the second syringe is 2 times or more, 5 times or more, 10 times or more, or 20 times or more the capacity of the first syringe. is there. When it comes to mixing chemicals with each other, unintended mixing may occur due to the difference in specific gravity of the chemicals. Therefore, such parameters may also be considered as whether or not to adopt the above-mentioned operation control.

Although the syringe 1090 has been described as an example, the above technique may be applied when a general syringe having a relatively large size is used instead of such a special syringe. Further, the above operation control has been described on the premise that the ram 1110 does not hold and fix the piston member of the syringe 200 at all. For example, the rear end of the piston member is held by a pair of claws (see reference numeral 143 of 12 in one example). Even with this configuration, there is a possibility that the piston member may move slightly due to some clearance, causing unintended movement of the chemical solution. Therefore, even in the case of such a configuration, the above-mentioned operation control may be adopted if necessary.

(P9. Reading data from bottles, etc.)
As one embodiment of the present invention, as shown in FIG. 46, in addition to the configuration as shown in FIG. 2, one or a plurality of chemical liquid containers 890A and 890B for storing the chemical liquid to be sucked into the syringe are set. A configuration in which the container holder 800 is provided may be adopted. Since the configuration of FIG. 46 is basically the same as that of FIG. 2 except for the configuration of the container holder 800 and the like, a duplicate description will be omitted. Although the detailed structure of the chemical solution circuit 900 is not shown, a circuit for connecting the chemical solution containers 890A and 890B and the syringes 200A and 200B is actually used so that suction from the chemical solution container can be performed. ..

The container holder 800, together with the injection head 110, may be supported by a movable support stand (eg, as in the container holder 104 of FIG. 23) or by a ceiling-suspended support arm (not shown). You may. The chemical solution holder 800 is provided with a reading device 500 that reads a display code 895, which is a data holding means attached to either or both of the chemical solution containers 890A and 890B (also simply referred to as the chemical solution container 890).

The display code 895 is, for example, an information holding medium such as a bar code or a two-dimensional code, and specifically, a matrix-type two-dimensional code such as a QR (Quick Response) code is used. You may. The information held by the display code 895 includes one or more of the chemical solution type, product name, manufacturing company name, expiration date, capacity, concentration, chemical solution container size, material, serial number, manufacturing date, etc. It may be a combination of. Specifically, the display code 895 may be a GS1 standard code, and has one or more information such as the manufacturing date, packing number, quality assurance date, order number, and quantity of the object. It may be. In one embodiment of the present invention, the display code 895 is one or more of a drug price standard listed drug code, an individual drug code, a code for a receipt computer processing system, a JAN code, a reference number (HOT code), an ATC code, and the like. Combinations may be included. Further, in addition to an information holding medium such as a barcode, an IC tag (RFID tag) that includes an IC chip and an antenna and exchanges information by wireless communication may be used.

The reading device 500 may have a unit for optically reading information. An optical reader is less likely to cause magnetic field interference in an MRI environment and is particularly suitable for a chemical injection device for MRI. When the chemical solution container 890 is set using such a configuration, predetermined information (in one example, one or a combination of contrast agent information, volume information, concentration information, and remaining amount information) is read. The information may be displayed on any display in the system. In addition, the chemical solution container may be collated using the information.

Although the plurality of embodiments of the present invention have been specifically described above, the present invention is not limited to the above-mentioned configuration and can be appropriately modified without departing from the spirit thereof. It is also possible to appropriately combine the contents disclosed as one embodiment and the contents disclosed as another embodiment.

This application discloses the following inventions:
(Appendix A)
1. 1. A holding mechanism for a chemical syringe having a cylinder member and a piston member slidably inserted therein, and a cylinder flange (231) formed at the rear end of the cylinder member.
An engaging recess (239) is formed on the rear surface of the cylinder flange.
A member having a receiving groove (175) for receiving a part of the cylinder flange (231),
An engaging member (176) arranged in the receiving groove and made of an elastic material,
With
As the cylinder flange is inserted into the receiving groove, the engaging member elastically fits into and engages with the engaging recess.
Flange holding mechanism.

2. The flange holding mechanism according to the above description, wherein at least two engaging members are provided so as to be located on both sides of the cylinder flange.

3. 3. The flange holding mechanism according to the above description, wherein a flange rib (237) is formed adjacent to the engaging recess.

4. The outer shape of the cylinder flange is circular, oval or oval,
The flange holding mechanism according to the above description, wherein the flange rib (237) is formed so as to extend in the horizontal direction. The mounting direction of the cylinder flange with respect to the flange holding mechanism is the vertical direction, and the "horizontal direction" is the direction orthogonal to it.

(Appendix B)
1. 1. A first piston drive mechanism having a ram member that moves back and forth to move the piston member of the first syringe,
A second piston drive mechanism having a ram member that moves back and forth to move the piston member of the second syringe,
A syringe holder for holding the first and second syringes and
With
The syringe holder is a chemical injection device provided at the tip of a center frame arranged so as to extend between the two ram members.

2. The chemical injection device described above, wherein the center frame is a carbon fiber material.

3. 3. The drug solution injector according to the above, wherein the center frame is a plate-shaped member.

4. The drug solution injector according to the above description, wherein the support member constituting the drug solution injector is not arranged on the side (the side opposite to the center frame) of the first and second syringes held in parallel.

5. The drug solution injector according to the above, wherein the center frame is fixed to a holding plate that holds a part of the first and second piston drive mechanisms.

6. The chemical injector according to the above, wherein the center frame and the holding plate are a single member of an integrally formed carbon fiber material.

7. The drug solution injector according to the above description, wherein the syringe holder is formed in a substantially U shape as a whole and is provided on one surface and the other surface of the center frame which is a plate-shaped member.

8. The drug solution injector according to the above description, further comprising a housing, wherein the center frame projects from the housing toward the front end side of the drug solution injector.

9. A chemical injection device including the above-described chemical injection device and a console connected to the chemical injection device.

(Appendix C)
1. 1. There is a gripping mechanism (140) that grips the piston flanges (221 and 241) of the piston member of the chemical syringe with a pair of rotating claws (143).
The pair of rotating claws (143) are configured to move between the closed state and the open state, and (i) when the piston member is brought closer to the pair of rotating claws in the closed state. , The piston flange presses against the tapered surface of the rotary claw, and the rotary claw rotates around a rotation axis (149) parallel to the axial direction of the piston member, whereby the piston flange is rotated by the pair of rotations. (Ii) When the piston flange enters between the pair of rotating claws, the pair of rotating claws are returned to the closed position by the urging force, and the pair of rotating claws return the pair of rotating claws to the closed state. A flange gripping mechanism (140) configured to grip the piston flange.

2. When gripping the piston flange, the flange gripping described above is configured so that one rotating claw and the other rotating claw move in opposite directions so as to be point-symmetric with respect to the center of the piston flange. mechanism.

3. 3. The flange gripping mechanism according to the above, wherein the tapered surface of the rotary claw abuts on the outer peripheral portion of the piston member.

4. The tapered surface is formed over a certain range in the radial direction of the piston flange.
The outer peripheral portion of the first size piston flange, which is relatively small in diameter, comes into contact with the tapered surface.
The flange gripping mechanism according to the above description, wherein the outer peripheral portion of a second size piston flange having a relatively large diameter is also configured to be able to come into contact with the tapered surface.

5. The flange gripping mechanism according to the above description, wherein the pair of rotary claws are formed at the tip portions of the pair of arms.

6. The arm is rotatable about a predetermined axis (141a), whereby the pair of rotating claws are close to each other in a first state and the pair of rotating claws are separated from each other in a second state. The flange gripping mechanism described above, which is configured to be movable to and from.

7. A piston drive mechanism (130) having a ram member (133) that moves the piston member of the chemical syringe forward and backward, and
The above-described flange gripping mechanism (140) provided at the tip of the ram member and
A chemical injection device.

8. The drug solution injection device according to the above description, which has two piston drive mechanisms, and each piston drive mechanism is provided with the flange gripping mechanism.

100 Chemical injection device 103 Holding stand 104 Container holder 110 Injection head 111 Housing 115 Control circuit 116 Support shaft 130 Piston drive mechanism 131 Motor 132 Transmission mechanism 132-1 Base module 132-2 Cylinder module 133 Ram member 135 Presser member 135a Pressing surface 138 Load cell 140 Flange gripping mechanism 141 Arm 143 Rotating claw 145 Claw part 145s Tapered surface (receiving surface)
146 Base 149 Axis 150 Console 151, 151-1 Display 153 Touch panel 155 Control 157 Switch 158 Housing 159 Storage 161 Physical button 170 Cylinder holder 171 First member 173 Second member 173h Hole 175 Receiving groove 175h Opening 176 Engagement member 181 Center frame 183 Holding plate 185 Shaft plate 200A, 200B (200) Syringe 210 Cylinder member 211 Cylinder flange 213 Conduit 220 Piston member 221 Piston flange 230 Cylinder member 230s Internal space 233 Conduit 231 Cylinder flange 237 Flange rib 239 Engagement recess 240 Piston member 241 Piston flange 243 Insertion part Cylinder part 245 Gasket 247 Shaft part 270 Syringe adapter 271 Flange holding part 271a Receiving groove 272 Recession 273 Cylinder holding part 277 Cylinder holding part 287 Thick part 287 Rib 289 Engaging recess 500 Device 800 Cylinder holder 890A, 890B Chemical solution container 895 Display code (data carrier)
900 Chemical solution circuit 911, 912, 913 Flow path 1090, 2090 Syringe 1091, 2091 Cylinder 1100, 2100 Gasket 1110 Ram 1111 Front end 1122 Engagement claw 1125 O-ring 2120 Sucker 2140 Seal member P110 Injection head P170 Syringe holder P200A , P200B Syringe P231 Cylinder Flange P270 Adapter P271 Adapter Flange P277 Holding Groove P601 Arm P615 Switching Mechanism O Center H Hole

Claims (1)

1. A chemical syringe having a cylindrical cylinder member and a piston member slidably inserted therein and filled with a chemical solution.
   The cylinder member has a substantially elliptical cross-sectional shape on a surface orthogonal to the axis thereof, and a cylinder flange is provided at an end on the side where the piston member is inserted.
   A chemical liquid syringe in which an engaging protrusion or an engaging concave portion with which an engaging member of a chemical liquid injector is engaged is formed on the rear surface of the cylinder flange.

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