WO2020195870A1 - Tubular therapeutic tool and film for tubular therapeutic tool - Google Patents

Tubular therapeutic tool and film for tubular therapeutic tool Download PDF

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Publication number
WO2020195870A1
WO2020195870A1 PCT/JP2020/010704 JP2020010704W WO2020195870A1 WO 2020195870 A1 WO2020195870 A1 WO 2020195870A1 JP 2020010704 W JP2020010704 W JP 2020010704W WO 2020195870 A1 WO2020195870 A1 WO 2020195870A1
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Prior art keywords
tubular
skeleton
stent graft
film
region
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PCT/JP2020/010704
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French (fr)
Japanese (ja)
Inventor
白濱　憲昭
崇志 吉森
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川澄化学工業株式会社
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Priority to JP2021509020A priority Critical patent/JP7473107B2/en
Publication of WO2020195870A1 publication Critical patent/WO2020195870A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts

Definitions

  • the present invention relates to a tubular therapeutic tool and a membrane body for a tubular therapeutic tool.
  • a stent graft has been conventionally known as a tubular therapeutic tool used for treating an aortic aneurysm or aortic dissection occurring in the aorta (see, for example, Patent Documents 1 and 2).
  • the stent graft includes, for example, a skeleton portion using a metal wire and a coating portion that covers the skeleton portion, and has a tubular outer shape as a whole.
  • the stent graft expands by applying an external force from the inside to the outside in the radial direction at a predetermined position in the blood vessel, and is placed in the blood vessel in close contact with the blood vessel.
  • the contact portion between the coating portion and the skeleton portion may rub. It is required to improve the durability of the stent graft against such rubbing between the skeleton portion and the coating portion.
  • An object of the present invention is to provide a tubular therapeutic tool having improved durability against rubbing between the skeleton portion and the coating portion.
  • One aspect of the present invention is It is a tubular treatment tool including a tubular main body portion, and the main body portion has a film portion made of a woven fiber and a skeleton portion provided on one surface of the film portion. A surface treatment portion processed so that the surface of the woven fabric becomes uneven is partially provided on one surface of the film portion.
  • the durability against rubbing between the skeleton portion and the coating portion can be improved.
  • FIG. 1 is a perspective view of the expanded state of the stent graft in one embodiment to which the present invention is applied
  • FIG. 3A is a diagram schematically showing a cross-sectional structure of a portion surrounded by a broken line in FIG. 3
  • FIG. 3B is a sectional view taken along line IVb-IVb of FIG. 4A. It is a figure which shows the outer peripheral surface side of another stent graft developed in a plane.
  • FIG. 1 is a perspective view of the expanded state of the stent graft 10 in one embodiment
  • FIG. 1 (B) is a plan view of the expanded state of the stent graft 10.
  • FIG. 2 is a diagram showing a state (use state) in which the stent graft 10 is placed in a blood vessel.
  • the stent graft 10 shown in FIGS. 1 and 2 is a branch blood vessel compatible main blood vessel stent graft, and has a tubular shape as a whole.
  • the stent graft 10 has openings provided at both ends in the axial direction Ax communicating with each other, and has a tubular flow path inside through which the patient's blood passes in the used state.
  • the stent graft 10 has a so-called self-expanding structure in which the shape of the expanded state is stored, and is introduced into the blood vessel in a state of being contracted inward in the radial direction (not shown).
  • the stent graft 10 is expanded by applying an external force from the inside to the outside in the radial direction at a predetermined position in the blood vessel (for example, a lesion site where an aortic aneurysm or the like is occurring) using an expansion catheter (not shown), and FIG. As shown, it is placed in the main blood vessel V1 in close contact with the inner wall of the blood vessel.
  • the stent graft 10 may be introduced into the blood vessel by a catheter different from the dilation catheter. Further, the stent graft 10 may be introduced into the blood vessel by being attached to the tip of the dilation catheter in a state of being contracted inward in the radial direction.
  • the stent graft 10 has a tubular body portion 10A and a branch portion 10B, respectively.
  • the main body portion 10A has a skeleton portion 11 and a tubular coating portion 12 provided along the skeleton portion 11.
  • a branch portion 10B is provided on the peripheral surface of the main body portion 10A.
  • the branch portion 10B is connected to the main body portion 10A so that the tubular flow path of the main body portion 10A and the internal space of the branch portion 10B communicate with each other.
  • the main body portion 10A of the stent graft 10 is placed in the main blood vessel V1 so that the branch portion 10B faces the branch blood vessel V2.
  • a branch blood vessel stent graft (not shown) is further connected to the branch portion 10B, and a branch blood vessel stent graft is placed in the branch blood vessel V2.
  • a straight tube-shaped stent graft 10 is shown.
  • the stent graft 10 of the present embodiment may have, for example, a shape curved in an arch shape (for example, a shape corresponding to the aortic arch of a patient) or a shape having a twist.
  • the skeleton portion 11 is a self-expanding stent skeleton configured to be deformable from a contracted state contracted inward in the radial direction to an expanded state expanded in the outward direction in the radial direction.
  • the skeleton portion 11 is composed of five skeleton pieces formed in a tubular shape with thin metal wires folded in a zigzag shape along the circumferential direction of the stent graft 10. These skeleton pieces are arranged side by side along the axial direction Ax. The adjacent skeleton pieces may be connected by a connecting member (not shown).
  • Examples of the material of the thin metal wire forming the skeleton portion 11 include known metals or metal alloys typified by stainless steel, nickel-titanium alloy, cobalt-chromium alloy, titanium alloy and the like.
  • the skeleton portion 11 may be made of a material other than metal (for example, ceramic or resin).
  • the cross-sectional shape of the thin metal wire of the skeleton portion 11 is, for example, a circle.
  • the cross-sectional shape of the thin metal wire of the skeleton portion 11 may be a rectangular shape or a shape in which the inside is flat and the outside is a curved surface (for example, a semicircle).
  • the film portion 12 is a tubular film body formed of a woven fiber, and forms the above-mentioned tubular flow path.
  • the material for forming the film portion 12 include a fluororesin such as PTFE (polytetrafluoroethylene) and a polyester resin such as polyethylene terephthalate.
  • the weaving method of the film portion 12 may be plain weave, twill weave, or satin weave.
  • a skeleton portion 11 is provided on the outer periphery of the film portion 12.
  • the film portion 12 is attached so as to close the gap portion of the skeleton portion 11.
  • the skeleton portion 11 is sewn on the outer peripheral surface of the film portion 12 with a thread 13, for example. Therefore, even when an instrument (for example, a catheter for introducing another stent graft) is passed through the inside of the stent graft 10, the instrument can be prevented from being caught on the inner surface of the stent graft 10.
  • an instrument for example, a catheter for introducing another stent graft
  • a recess 14 recessed inward in the radial direction is formed in a part of the pipe wall (in FIGS. 1A and 1B, a substantially central portion in the axial direction of the main body portion 10A).
  • a branch portion 10B is formed at substantially the center of the flat bottom surface of the recess 14 so as to project outward in the radial direction of the main body portion 10A.
  • the branch portion 10B has a tubular shape as described above, and functions as a connection portion for connecting a branch vascular stent graft.
  • the branch portion 10B has a flexibility (flexibility) such that the direction of the opening can be changed by, for example, the blood flow from the main blood vessel V1 to the branch blood vessel V2.
  • the shape of the branch portion 10B is shown as a cylindrical shape, but the shape of the branch portion 10B may be a tapered shape (conical truncated cone shape) in which the diameter is reduced toward the tip side. , Or it may be in the shape of a square cylinder or a truncated cone.
  • the branch portion 10B is formed of, for example, the same material as the coating portion 12, and is configured as one member together with the coating portion 12.
  • the film of the branch portion 10B may be formed of a member separate from the main body portion 10A and may be joined to the film portion 12.
  • the film of the branch portion 10B may be formed of the same material as the film portion 12, or may be formed of a different material.
  • FIGS. 1 and 2 show an example in which the skeleton portion is not arranged on the branch portion 10B, the skeleton portion may be arranged on the peripheral surface of the branch portion 10B.
  • FIG. 3 is a schematic view showing a part of the stent graft 10 in the circumferential direction cut open and the outer peripheral surface side developed in a plane.
  • the vertical direction in FIG. 3 corresponds to the axial direction Ax of the stent graft 10
  • the horizontal direction in FIG. 3 corresponds to the circumferential direction Ci of the stent graft 10.
  • the vertical direction of the paper surface in FIG. 3 corresponds to the radial direction Ra of the stent graft 10.
  • FIG. 4A is a diagram schematically showing a cross-sectional structure of a portion surrounded by a broken line in FIG. 3, and
  • FIG. 4B is a sectional view taken along line IVb-IVb of FIG. 4A.
  • the outer peripheral surface of the coating portion 12 of the stent graft 10 has a first region 21 as a surface-treated portion and a woven fabric of the coating portion 12 which has not been surface-treated.
  • a second area 22 is provided in which the ground is exposed as it is.
  • the first region 21 is provided on the outer peripheral surface of the film portion 12 with reference to the position of the skeleton portion 11, and is arranged so that at least the apex portions of the skeleton portion 11 that are folded back in a zigzag shape correspond to each other. It is set up.
  • FIG. 1 the outer peripheral surface of the coating portion 12 of the stent graft 10 has a first region 21 as a surface-treated portion and a woven fabric of the coating portion 12 which has not been surface-treated.
  • a second area 22 is provided in which the ground is exposed as it is.
  • the first region 21 is provided on the outer peripheral surface of the film portion 12 with reference to the position of the skeleton portion 11, and is arranged so that at least the
  • a plurality of circular first regions 21 are periodically arranged in a predetermined pattern (for example, in a staggered pattern) at intervals, and the first regions 21 are arranged.
  • a predetermined pattern for example, in a staggered pattern
  • the space is the second region 22.
  • the first region 21 is formed so as to have irregularities on the woven fabric or to be recessed from the flat second region 22, and has a surface that is difficult to contact with the skeleton portion 11.
  • the first region 21 and the second region 22 form irregularities on the outer peripheral surface of the film portion 12, and the surface roughness of the outer peripheral surface of the film portion 12 is increased.
  • a contact area between the surface of the second region 22 and the inside of the skeleton portion 11 is secured, but it is difficult to contact the inside of the skeleton portion 11.
  • the contact area is reduced by the amount of the first region 21.
  • the first region 21 is formed, for example, by calendar processing in which the woven fabric is pressed using a roller having a convex surface formed corresponding to the pattern of the first region 21.
  • the second region 22 may be surface-treated so that the surface of the woven fabric becomes flatter in order to facilitate contact with the inside of the skeleton portion 11.
  • it may be pressurized by a portion other than the convex surface of the roller for forming the first region 21, or may be coated with a biocompatible coating agent so as to be flatter.
  • FIGS. 4A and 4B show an example in which the woven fabric of the film portion 12 is subjected to calendar processing to form the first region 21.
  • the skeleton portion 11 is arranged so as to straddle the first region 21 and the second region 22, and the thread is formed on the coating portion 12. It is sewn at 13. Therefore, as shown in FIG. 4A, the inside of the skeleton portion 11 comes into contact with the surface of the second region 22 provided on the outer peripheral surface of the coating portion 12.
  • the main body 10A expands radially outward due to the pressure of blood flowing inside the main body 10A. Therefore, in the state of using the stent graft 10, a force acts on the coating portion 12 in the radial direction, and the outer peripheral surface of the coating portion 12 is pressed against the inside of the skeleton portion 11 so that the two are in close contact with each other. Become.
  • the skeleton portion 11 and the coating portion 12 may be displaced on the peripheral surface of the stent graft 10 due to the influence of such vibration.
  • the outer peripheral surface of the film portion 12 has a large surface roughness due to the unevenness formed by the first region 21 and the second region 22, the contact area between the skeleton portion 11 and the film portion 12 is reduced. Even if the skeleton portion 11 and the coating portion 12 are misaligned due to the pulsation of blood vessels or the like, the amount of wear is reduced.
  • the stent graft 10 of the present embodiment includes a tubular main body portion 10A, and the main body portion 10A is provided on a film portion 12 made of a woven fiber and one surface (for example, an outer peripheral surface) of the film portion 12. It has a skeleton portion 11.
  • a surface-treated portion (for example, the first region 21) is partially provided on one surface of the film portion 12 so that the surface of the woven fabric becomes uneven.
  • the outer peripheral surface of the coating portion 12 is processed so that the surface becomes uneven, so that the surface roughness can be increased, and the skeleton portion 11 and the coating portion 12 Even if the position shift occurs, the film portion 12 can be made less likely to be worn as compared with the configuration in which the first region 21 is not provided. As a result, the durability against rubbing between the skeleton portion 11 and the coating portion 12 can be improved.
  • the contact area between the surface of the second region 22 and the inside of the skeleton portion 11 is secured, it is possible to generate a frictional force that suppresses the positional deviation between the skeleton portion 11 and the coating portion 12.
  • the misalignment between the skeleton portion 11 and the coating portion 12 can be suppressed.
  • by forming the surface of the second region 22 more flat so that it can easily come into contact with the inside of the skeleton portion 11 made of fine metal wires unevenness at the interface between the second region 22 and the skeleton portion 11 is formed. It is possible to cause almost no meshing.
  • the second region 22 of the coating portion 12 can be made less likely to be worn.
  • the stent graft 10 when the inner wall of the flexible blood vessel is deformed so as to be in close contact with the unevenness of the first region 21 and the second region 22, it is formed between the coating portion 12 and the inner wall of the blood vessel.
  • the contact area becomes large and a large frictional force can be generated. Therefore, by providing the first region 21 and the second region 22 on the outer peripheral surface of the film portion 12, the friction when the stent graft 10 is in close contact with the inner wall of the blood vessel can be increased. As a result, it is possible to prevent the stent graft 10 from being displaced from a predetermined position in the blood vessel.
  • the skeleton portion 11 is sewn to the film portion 12, but the present invention is not limited to this, and the skeleton portion 11 is attached to the film portion 12 by, for example, sticking, adhering, or welding with tape. It may be attached. Further, the film portion 12 may be arranged on the outer peripheral side of the skeleton portion 11, or the skeleton portion 11 may be arranged between the two film portions 12 so as to sandwich the skeleton portion 11 from the outside and the inside.
  • each first region 21 may be any shape such as a polygon or an ellipse.
  • the arrangement pattern of the first region 21 in the film portion 12 may be another pattern such as a grid pattern. Further, the positional relationship between the first region 21 and the second region 22 in the film portion 12 illustrated in the above embodiment may be exchanged.
  • a plurality of first regions 21 are formed on the outer peripheral surface of the film portion 12 in a zigzag shape so as to correspond to the shape of the skeleton portion 11, and the plurality of first regions 21 are formed.
  • the skeleton portion 11 may be attached along the region 21 of 1.
  • the first region 21 may be provided at the seam portion where the film portion 12 is easily rubbed.
  • the first region 21 is provided at the position of the folded portion of the skeleton portion 11 having many seams on the outer peripheral surface of the film portion 12, the rubbing of the film portion 12 can be effectively suppressed.
  • the second region 22 may be provided in the seam portion, and in this case, the contact area between the surface of the second region 22 and the inside of the skeleton portion 11 can be more appropriately secured. Therefore, the misalignment between the skeleton portion 11 and the coating portion 12 can be effectively suppressed.
  • Stent graft tubular treatment tool
  • Main body 11
  • Skeleton 12 Coating 13
  • Thread 21
  • Second area 22

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  • Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

A stent graft (10) comprising a tubular body section (10A), wherein the body section has a film section (12) comprising a fibrous textile, and a skeleton section (11) provided to one surface of the film section. The one surface of the film section is partially provided with first regions (21) where processing so as to make the surface of the textile become rugged has been performed.

Description

管状治療具および管状治療具用膜体Tubular treatment tool and membrane body for tubular treatment tool
　本発明は、管状治療具および管状治療具用膜体に関する。 The present invention relates to a tubular therapeutic tool and a membrane body for a tubular therapeutic tool.
　例えば、大動脈に生じた大動脈瘤や大動脈解離などの治療に用いられる管状治療具として、ステントグラフトが従来から知られている（例えば、特許文献１、２参照）。
　ステントグラフトは、例えば、金属線を用いた骨格部と、骨格部を被覆する皮膜部を含み、全体として管状の外形をなす。ステントグラフトは、血管内の所定位置において内側から径方向外側に外力が加えられることで拡張し、血管と密着した状態で血管内に留置される。 For example, a stent graft has been conventionally known as a tubular therapeutic tool used for treating an aortic aneurysm or aortic dissection occurring in the aorta (see, for example, Patent Documents 1 and 2).
The stent graft includes, for example, a skeleton portion using a metal wire and a coating portion that covers the skeleton portion, and has a tubular outer shape as a whole. The stent graft expands by applying an external force from the inside to the outside in the radial direction at a predetermined position in the blood vessel, and is placed in the blood vessel in close contact with the blood vessel.
特許第６１３１４４１号公報Japanese Patent No. 6131441 特許第５８２４７５９号公報Japanese Patent No. 5824759
　ところで、ステントグラフトは、使用時に血管の脈動などにより変形すると、皮膜部と骨格部の接触部分が擦れることがある。このような骨格部と皮膜部との擦れに対してステントグラフトの耐久性を向上させることが要望されている。 By the way, if the stent graft is deformed due to the pulsation of blood vessels during use, the contact portion between the coating portion and the skeleton portion may rub. It is required to improve the durability of the stent graft against such rubbing between the skeleton portion and the coating portion.
　本発明の目的は、骨格部と皮膜部との擦れに対する耐久性を向上させた管状治療具を提供することである。 An object of the present invention is to provide a tubular therapeutic tool having improved durability against rubbing between the skeleton portion and the coating portion.
　本発明の一態様は、
　管状の本体部を備える管状治療具であって、本体部は、繊維の織物からなる皮膜部と、皮膜部の一面に設けられる骨格部と、を有する。皮膜部の一面には、織物の表面が凹凸になるように加工された表面処理部が部分的に設けられている。 One aspect of the present invention is
It is a tubular treatment tool including a tubular main body portion, and the main body portion has a film portion made of a woven fiber and a skeleton portion provided on one surface of the film portion. A surface treatment portion processed so that the surface of the woven fabric becomes uneven is partially provided on one surface of the film portion.
　本発明の一態様の管状治療具によれば、骨格部と皮膜部との擦れに対する耐久性を向上させることができる。 According to the tubular treatment tool of one aspect of the present invention, the durability against rubbing between the skeleton portion and the coating portion can be improved.
（Ａ）は本発明を適用した一実施形態におけるステントグラフトの拡張状態の斜視図であり、（Ｂ）はステントグラフトの拡張状態の平面図である。(A) is a perspective view of the expanded state of the stent graft in one embodiment to which the present invention is applied, and (B) is a plan view of the expanded state of the stent graft. ステントグラフトを血管内に留置させた状態を示す図である。It is a figure which shows the state which the stent graft was indwelled in the blood vessel. ステントグラフトの外周面側を平面状に展開して模式的に示す図である。It is a figure which shows typically the outer peripheral surface side of a stent graft developed in a plane. （Ａ）は、図３において破線で囲った部分の断面構造を模式的に示す図であり、（Ｂ）は図４（Ａ）のIVb-IVb線断面図である。FIG. 3A is a diagram schematically showing a cross-sectional structure of a portion surrounded by a broken line in FIG. 3, and FIG. 3B is a sectional view taken along line IVb-IVb of FIG. 4A. 他のステントグラフトの外周面側を平面状に展開して示す図である。It is a figure which shows the outer peripheral surface side of another stent graft developed in a plane.
　以下、本発明の実施形態について図面を参照して説明する。
　後述の各図では、管状治療具の一実施形態としてのステントグラフト１０の構成例を模式的に表している。図面におけるステントグラフト１０の形状、寸法等は模式的に示したもので、実際の形状や寸法等を示すものではない。 Hereinafter, embodiments of the present invention will be described with reference to the drawings.
In each figure described later, a configuration example of the stent graft 10 as an embodiment of the tubular treatment tool is schematically shown. The shapes, dimensions, etc. of the stent graft 10 in the drawings are schematically shown, and do not show the actual shapes, dimensions, etc.
　図１は、一実施形態におけるステントグラフト１０の拡張状態の斜視図であり、図１（Ｂ）はステントグラフト１０の拡張状態の平面図である。図２は、ステントグラフト１０を血管内に留置させた状態（使用状態）を示す図である。 FIG. 1 is a perspective view of the expanded state of the stent graft 10 in one embodiment, and FIG. 1 (B) is a plan view of the expanded state of the stent graft 10. FIG. 2 is a diagram showing a state (use state) in which the stent graft 10 is placed in a blood vessel.
　図１、図２に示すステントグラフト１０は、分枝血管対応型の主血管用ステントグラフトであり、全体形状が管状をなしている。ステントグラフト１０は、軸方向Ａｘの両端部に設けられた開口が連通しており、使用状態において患者の血液が通過する管状流路を内部に有している。 The stent graft 10 shown in FIGS. 1 and 2 is a branch blood vessel compatible main blood vessel stent graft, and has a tubular shape as a whole. The stent graft 10 has openings provided at both ends in the axial direction Ax communicating with each other, and has a tubular flow path inside through which the patient's blood passes in the used state.
　ステントグラフト１０は、拡張状態の形状が記憶された、いわゆる自己拡張型の構成を有し、径方向内側に収縮された状態（不図示）で血管内に導入される。ステントグラフト１０は、血管内の所定位置（例えば、大動脈瘤等が生じている病変部位）で、図示しない拡張用カテーテルを用いて内側から径方向外側に外力が加えられることで拡張し、図２に示すように血管内壁と密着した状態で主血管Ｖ１内に留置される。
　ステントグラフト１０は、拡張用カテーテルとは別のカテーテルによって血管内に導入されてもよい。また、ステントグラフト１０は、径方向内側に収縮された状態で拡張用カテーテルの先端に装着されることで血管内に導入されてもよい。 The stent graft 10 has a so-called self-expanding structure in which the shape of the expanded state is stored, and is introduced into the blood vessel in a state of being contracted inward in the radial direction (not shown). The stent graft 10 is expanded by applying an external force from the inside to the outside in the radial direction at a predetermined position in the blood vessel (for example, a lesion site where an aortic aneurysm or the like is occurring) using an expansion catheter (not shown), and FIG. As shown, it is placed in the main blood vessel V1 in close contact with the inner wall of the blood vessel.
The stent graft 10 may be introduced into the blood vessel by a catheter different from the dilation catheter. Further, the stent graft 10 may be introduced into the blood vessel by being attached to the tip of the dilation catheter in a state of being contracted inward in the radial direction.
　ステントグラフト１０は、それぞれ管状の本体部１０Ａおよび分枝部１０Ｂを有する。
　本体部１０Ａは、骨格部１１と、骨格部１１に沿って設けられる管状の皮膜部１２とを有する。本体部１０Ａの周面には、分枝部１０Ｂが設けられている。分枝部１０Ｂは、本体部１０Ａの管状流路と分枝部１０Ｂの内部空間とが連通するように本体部１０Ａと接続されている。 The stent graft 10 has a tubular body portion 10A and a branch portion 10B, respectively.
The main body portion 10A has a skeleton portion 11 and a tubular coating portion 12 provided along the skeleton portion 11. A branch portion 10B is provided on the peripheral surface of the main body portion 10A. The branch portion 10B is connected to the main body portion 10A so that the tubular flow path of the main body portion 10A and the internal space of the branch portion 10B communicate with each other.
　図２に示すステントグラフト１０の使用状態においては、分枝部１０Ｂが分枝血管Ｖ２に臨むように、ステントグラフト１０の本体部１０Ａが主血管Ｖ１内に留置される。この状態において分枝部１０Ｂに分枝血管用ステントグラフト（不図示）をさらに接続し、分枝血管Ｖ２に分枝血管用ステントグラフトを留置する。これにより、主血管Ｖ１と分枝血管Ｖ２との血流の維持が図られる。 In the state of use of the stent graft 10 shown in FIG. 2, the main body portion 10A of the stent graft 10 is placed in the main blood vessel V1 so that the branch portion 10B faces the branch blood vessel V2. In this state, a branch blood vessel stent graft (not shown) is further connected to the branch portion 10B, and a branch blood vessel stent graft is placed in the branch blood vessel V2. As a result, the blood flow between the main blood vessel V1 and the branch blood vessel V2 is maintained.
　図１、図２の例では、直管形状のステントグラフト１０を示している。もっとも、本実施形態のステントグラフト１０は、例えば、弓状に湾曲した形状（例えば、患者の大動脈弓に対応した形状）であってもよく、捻れを有する形状であってもよい。 In the examples of FIGS. 1 and 2, a straight tube-shaped stent graft 10 is shown. However, the stent graft 10 of the present embodiment may have, for example, a shape curved in an arch shape (for example, a shape corresponding to the aortic arch of a patient) or a shape having a twist.
　骨格部１１は、径方向内側に収縮した収縮状態から、径方向外側に拡張した拡張状態へと変形可能に構成された自己拡張型のステント骨格である。本実施形態では、骨格部１１は、ステントグラフト１０の周方向に沿うようにジグザグ状に折り返される金属細線で管状に形成した５つの骨格片で構成される。これらの骨格片は軸方向Ａｘに沿って並設されている。なお、隣接する骨格片同士は、連結部材（不図示）で連結されていてもよい。 The skeleton portion 11 is a self-expanding stent skeleton configured to be deformable from a contracted state contracted inward in the radial direction to an expanded state expanded in the outward direction in the radial direction. In the present embodiment, the skeleton portion 11 is composed of five skeleton pieces formed in a tubular shape with thin metal wires folded in a zigzag shape along the circumferential direction of the stent graft 10. These skeleton pieces are arranged side by side along the axial direction Ax. The adjacent skeleton pieces may be connected by a connecting member (not shown).
　骨格部１１を形成する金属細線の材料としては、例えば、ステンレス鋼、ニッケル－チタン合金、コバルト－クロム合金、チタン合金等に代表される公知の金属又は金属合金が挙げられる。なお、骨格部１１は、金属以外の材料（例えば、セラミックや樹脂等）で形成されていてもよい。
　後述の図４（Ｂ）に示すように、骨格部１１の金属細線の横断面形状は、例えば円形である。なお、骨格部１１の金属細線の横断面形状は、矩形状や、内側が平坦で外側が曲面である形状（例えば半円形など）であってもよい。 Examples of the material of the thin metal wire forming the skeleton portion 11 include known metals or metal alloys typified by stainless steel, nickel-titanium alloy, cobalt-chromium alloy, titanium alloy and the like. The skeleton portion 11 may be made of a material other than metal (for example, ceramic or resin).
As shown in FIG. 4 (B) described later, the cross-sectional shape of the thin metal wire of the skeleton portion 11 is, for example, a circle. The cross-sectional shape of the thin metal wire of the skeleton portion 11 may be a rectangular shape or a shape in which the inside is flat and the outside is a curved surface (for example, a semicircle).
　皮膜部１２は、繊維の織物で形成された管状の膜体であって、上述の管状流路を形成する。
　皮膜部１２を形成する材料としては、例えば、ＰＴＦＥ（ポリテトラフルオロエチレン）等のフッ素樹脂、ポリエチレンテレフタレート等のポリエステル樹脂等が挙げられる。なお、皮膜部１２の織り方は、平織り、綾織り、繻子織りのいずれであってもよい。 The film portion 12 is a tubular film body formed of a woven fiber, and forms the above-mentioned tubular flow path.
Examples of the material for forming the film portion 12 include a fluororesin such as PTFE (polytetrafluoroethylene) and a polyester resin such as polyethylene terephthalate. The weaving method of the film portion 12 may be plain weave, twill weave, or satin weave.
　皮膜部１２の外周に、骨格部１１が設けられている。皮膜部１２は、骨格部１１の隙間部分を閉塞するように取り付けられている。骨格部１１は、例えば、皮膜部１２の外周面に糸１３で縫い付けられている。このため、ステントグラフト１０の内部に器具（例えば、別のステントグラフトを導入するためのカテーテル）を通す手技を行う場合であっても、ステントグラフト１０の内面に器具が引っかかり難くすることができる。 A skeleton portion 11 is provided on the outer periphery of the film portion 12. The film portion 12 is attached so as to close the gap portion of the skeleton portion 11. The skeleton portion 11 is sewn on the outer peripheral surface of the film portion 12 with a thread 13, for example. Therefore, even when an instrument (for example, a catheter for introducing another stent graft) is passed through the inside of the stent graft 10, the instrument can be prevented from being caught on the inner surface of the stent graft 10.
　皮膜部１２には、管壁の一部（図１（Ａ）、（Ｂ）では、本体部１０Ａの軸方向における略中央部）に、径方向内側に窪んだ凹部１４が形成されている。凹部１４の平坦な底面の略中央には、本体部１０Ａの径方向の外側に突出するように分枝部１０Ｂが形成されている。 In the film portion 12, a recess 14 recessed inward in the radial direction is formed in a part of the pipe wall (in FIGS. 1A and 1B, a substantially central portion in the axial direction of the main body portion 10A). A branch portion 10B is formed at substantially the center of the flat bottom surface of the recess 14 so as to project outward in the radial direction of the main body portion 10A.
　分枝部１０Ｂは、上述のように管状をなしており、分枝血管用ステントグラフトを接続するための接続部として機能する。分枝部１０Ｂは、例えば、主血管Ｖ１から分枝血管Ｖ２への血流によって、開口の向きを変更できる程度の柔軟性（フレキシビリティ）を有する。
　図１、図２の例では、分枝部１０Ｂの形状を円筒形状で示すが、分枝部１０Ｂの形状は、先端側に向けて縮径するテーパー形状（円錐台形状）であってもよく、あるいは角筒形状や角錐台形状などであってもよい。 The branch portion 10B has a tubular shape as described above, and functions as a connection portion for connecting a branch vascular stent graft. The branch portion 10B has a flexibility (flexibility) such that the direction of the opening can be changed by, for example, the blood flow from the main blood vessel V1 to the branch blood vessel V2.
In the examples of FIGS. 1 and 2, the shape of the branch portion 10B is shown as a cylindrical shape, but the shape of the branch portion 10B may be a tapered shape (conical truncated cone shape) in which the diameter is reduced toward the tip side. , Or it may be in the shape of a square cylinder or a truncated cone.
　分枝部１０Ｂは、例えば、皮膜部１２と同じ材料で形成され、皮膜部１２とともに一部材として構成される。なお、分枝部１０Ｂの皮膜を本体部１０Ａとは別部材で構成し、皮膜部１２に接合してもよい。この場合、分枝部１０Ｂの皮膜は、皮膜部１２と同じ材料で形成してもよく、異なる材料で形成してもよい。
　なお、図１、図２では、分枝部１０Ｂには骨格部を配置しない例を示すが、分枝部１０Ｂの周面に骨格部を配置するようにしてもよい。 The branch portion 10B is formed of, for example, the same material as the coating portion 12, and is configured as one member together with the coating portion 12. The film of the branch portion 10B may be formed of a member separate from the main body portion 10A and may be joined to the film portion 12. In this case, the film of the branch portion 10B may be formed of the same material as the film portion 12, or may be formed of a different material.
Although FIGS. 1 and 2 show an example in which the skeleton portion is not arranged on the branch portion 10B, the skeleton portion may be arranged on the peripheral surface of the branch portion 10B.
　図３は、ステントグラフト１０の周方向の一部を切り開いて外周面側を平面状に展開して示した模式図である。図３の上下方向はステントグラフト１０の軸方向Ａｘに対応し、図３の左右方向はステントグラフト１０の周方向Ｃｉに対応する。また、図３の紙面垂直方向はステントグラフト１０の径方向Ｒａに対応する。
　図４（Ａ）は、図３において破線で囲った部分の断面構造を模式的に示す図であり、図４（Ｂ）は、図４（Ａ）のIVb-IVb線断面図である。 FIG. 3 is a schematic view showing a part of the stent graft 10 in the circumferential direction cut open and the outer peripheral surface side developed in a plane. The vertical direction in FIG. 3 corresponds to the axial direction Ax of the stent graft 10, and the horizontal direction in FIG. 3 corresponds to the circumferential direction Ci of the stent graft 10. Further, the vertical direction of the paper surface in FIG. 3 corresponds to the radial direction Ra of the stent graft 10.
FIG. 4A is a diagram schematically showing a cross-sectional structure of a portion surrounded by a broken line in FIG. 3, and FIG. 4B is a sectional view taken along line IVb-IVb of FIG. 4A.
　図３に示すように、ステントグラフト１０の皮膜部１２の外周面には、表面加工が施された表面処理部としての第１の領域２１と、表面加工が施されておらず皮膜部１２の織物地がそのまま露出する第２の領域２２が設けられている。
　第１の領域２１は、骨格部１１の位置を基準として皮膜部１２の外周面に設けられており、例えば、骨格部１１のうち、少なくともジグザグ状に折り返された頂点部分が対応するように配設されている。図３では、皮膜部１２の外周面において、円形状の複数の第１の領域２１が間隔を空けて所定のパターン（例えば、千鳥状）で周期的に配列され、これら第１の領域２１の間が第２の領域２２となる例を示す。 As shown in FIG. 3, the outer peripheral surface of the coating portion 12 of the stent graft 10 has a first region 21 as a surface-treated portion and a woven fabric of the coating portion 12 which has not been surface-treated. A second area 22 is provided in which the ground is exposed as it is.
The first region 21 is provided on the outer peripheral surface of the film portion 12 with reference to the position of the skeleton portion 11, and is arranged so that at least the apex portions of the skeleton portion 11 that are folded back in a zigzag shape correspond to each other. It is set up. In FIG. 3, on the outer peripheral surface of the film portion 12, a plurality of circular first regions 21 are periodically arranged in a predetermined pattern (for example, in a staggered pattern) at intervals, and the first regions 21 are arranged. An example is shown in which the space is the second region 22.
　図４（Ａ）に示すように、第１の領域２１は、織物地の凹凸を有するか平坦な第２の領域２２よりも凹むように形成され、骨格部１１と接し難い表面を有している。すなわち、第１の領域２１と第２の領域２２とにより、皮膜部１２の外周面には凹凸が形成されており、皮膜部１２の外周面の表面粗さが大きくされている。
　これにより、骨格部１１と皮膜部１２とが密着したとき、第２の領域２２の表面と骨格部１１の内側の間での接触面積が確保されるが、骨格部１１の内側と接触し難い第１の領域２１の分だけ接触面積が低減される。 As shown in FIG. 4A, the first region 21 is formed so as to have irregularities on the woven fabric or to be recessed from the flat second region 22, and has a surface that is difficult to contact with the skeleton portion 11. There is. That is, the first region 21 and the second region 22 form irregularities on the outer peripheral surface of the film portion 12, and the surface roughness of the outer peripheral surface of the film portion 12 is increased.
As a result, when the skeleton portion 11 and the coating portion 12 are in close contact with each other, a contact area between the surface of the second region 22 and the inside of the skeleton portion 11 is secured, but it is difficult to contact the inside of the skeleton portion 11. The contact area is reduced by the amount of the first region 21.
　第１の領域２１の形成方法は、公知の加工技術のうちから任意の方法を採用可能である。第１の領域２１は、例えば、第１の領域２１のパターンに対応する凸面が形成されたローラを用いて織物地をプレスするカレンダー加工によって形成される。
　また、第２の領域２２は、骨格部１１の内側と接触し易くするために、織物地の表面がより平坦となるように表面処理が施されてもよい。例えば、第１の領域２１を形成するためのローラの凸面以外の部分により加圧されてもよいし、生体適合性を有するコーティング剤でより平坦となるようにコーティングが施されてもよい。
　なお、図４（Ａ）、（Ｂ）では、皮膜部１２の織物地にカレンダー加工を施して第１の領域２１を形成した例を示している。 As a method for forming the first region 21, any known processing technique can be adopted. The first region 21 is formed, for example, by calendar processing in which the woven fabric is pressed using a roller having a convex surface formed corresponding to the pattern of the first region 21.
Further, the second region 22 may be surface-treated so that the surface of the woven fabric becomes flatter in order to facilitate contact with the inside of the skeleton portion 11. For example, it may be pressurized by a portion other than the convex surface of the roller for forming the first region 21, or may be coated with a biocompatible coating agent so as to be flatter.
Note that FIGS. 4A and 4B show an example in which the woven fabric of the film portion 12 is subjected to calendar processing to form the first region 21.
　図３、図４（Ａ）に示すように、皮膜部１２の外周面において、骨格部１１は、第１の領域２１および第２の領域２２に跨がって配置され、皮膜部１２に糸１３で縫い付けられている。そのため、図４（Ａ）に示すように、骨格部１１の内側は、皮膜部１２の外周面に設けられた第２の領域２２の表面と接触する。 As shown in FIGS. 3 and 4A, on the outer peripheral surface of the coating portion 12, the skeleton portion 11 is arranged so as to straddle the first region 21 and the second region 22, and the thread is formed on the coating portion 12. It is sewn at 13. Therefore, as shown in FIG. 4A, the inside of the skeleton portion 11 comes into contact with the surface of the second region 22 provided on the outer peripheral surface of the coating portion 12.
　ステントグラフト１０の使用状態においては、本体部１０Ａの内側を流れる血液の圧力で本体部１０Ａが径方向外側に膨張する。したがって、ステントグラフト１０の使用状態では、皮膜部１２に対しては径方向外側に向けて力が作用し、皮膜部１２の外周面が骨格部１１の内側に押し当てられて両者が密着した状態となる。
　ここで、ステントグラフト１０に対して血管の脈動による周期的な振動が加わると、このような振動の影響で、ステントグラフト１０の周面上で骨格部１１と皮膜部１２の位置ずれが生じうる。しかしながら、皮膜部１２の外周面は、第１の領域２１と第２の領域２２とにより形成された凹凸により表面粗さが大きいため、骨格部１１と皮膜部１２との接触面積が低減し、血管の脈動等で骨格部１１と皮膜部１２の位置ずれが生じても摩耗量が低減する。 In the state of using the stent graft 10, the main body 10A expands radially outward due to the pressure of blood flowing inside the main body 10A. Therefore, in the state of using the stent graft 10, a force acts on the coating portion 12 in the radial direction, and the outer peripheral surface of the coating portion 12 is pressed against the inside of the skeleton portion 11 so that the two are in close contact with each other. Become.
Here, when periodic vibration due to the pulsation of blood vessels is applied to the stent graft 10, the skeleton portion 11 and the coating portion 12 may be displaced on the peripheral surface of the stent graft 10 due to the influence of such vibration. However, since the outer peripheral surface of the film portion 12 has a large surface roughness due to the unevenness formed by the first region 21 and the second region 22, the contact area between the skeleton portion 11 and the film portion 12 is reduced. Even if the skeleton portion 11 and the coating portion 12 are misaligned due to the pulsation of blood vessels or the like, the amount of wear is reduced.
　以上のように、本実施形態のステントグラフト１０は、管状の本体部１０Ａを備え、本体部１０Ａは、繊維の織物からなる皮膜部１２と、皮膜部１２の一面（例えば、外周面）に設けられる骨格部１１と、を有する。皮膜部１２の一面には、織物の表面が凹凸になるように加工された表面処理部（例えば、第１の領域２１）が部分的に設けられている。
　本実施形態のステントグラフト１０によれば、皮膜部１２の外周面は、表面が凹凸になるように加工されていることで、表面粗さを大きくすることができ、骨格部１１と皮膜部１２の位置ずれが生じたとしても、第１の領域２１を設けない構成に比べて皮膜部１２を摩耗しにくくすることができる。これにより、骨格部１１と皮膜部１２との擦れに対する耐久性を向上させることができる。 As described above, the stent graft 10 of the present embodiment includes a tubular main body portion 10A, and the main body portion 10A is provided on a film portion 12 made of a woven fiber and one surface (for example, an outer peripheral surface) of the film portion 12. It has a skeleton portion 11. A surface-treated portion (for example, the first region 21) is partially provided on one surface of the film portion 12 so that the surface of the woven fabric becomes uneven.
According to the stent graft 10 of the present embodiment, the outer peripheral surface of the coating portion 12 is processed so that the surface becomes uneven, so that the surface roughness can be increased, and the skeleton portion 11 and the coating portion 12 Even if the position shift occurs, the film portion 12 can be made less likely to be worn as compared with the configuration in which the first region 21 is not provided. As a result, the durability against rubbing between the skeleton portion 11 and the coating portion 12 can be improved.
　また、第２の領域２２の表面と骨格部１１の内側の間での接触面積が確保されているため、骨格部１１と皮膜部１２の位置ずれを抑制する摩擦力を発生させることができ、骨格部１１と皮膜部１２の位置ずれを抑制できる。特に、第２の領域２２の表面を金属細線で構成された骨格部１１の内側と接触し易いようにより平坦に形成することで、第２の領域２２と骨格部１１の間では界面における凹凸の噛み合いをほとんど生じさせないようにできる。これにより、血管の脈動等で骨格部１１と皮膜部１２の位置ずれが生じても皮膜部１２の第２の領域２２を摩耗しにくくすることができる。
　さらに、ステントグラフト１０が血管に留置されたときに、柔軟な血管の内壁が第１の領域２１と第２の領域２２の凹凸に密着するように変形すると、皮膜部１２と血管内壁との間で接触面積が大きくなり、大きな摩擦力を生じさせ得る。
　そのため、皮膜部１２の外周面に第１の領域２１および第２の領域２２を設けることで、ステントグラフト１０が血管内壁と密着したときの摩擦が大きくすることができる。これにより、ステントグラフト１０が血管内の所定位置からずれることを抑制できる。 Further, since the contact area between the surface of the second region 22 and the inside of the skeleton portion 11 is secured, it is possible to generate a frictional force that suppresses the positional deviation between the skeleton portion 11 and the coating portion 12. The misalignment between the skeleton portion 11 and the coating portion 12 can be suppressed. In particular, by forming the surface of the second region 22 more flat so that it can easily come into contact with the inside of the skeleton portion 11 made of fine metal wires, unevenness at the interface between the second region 22 and the skeleton portion 11 is formed. It is possible to cause almost no meshing. As a result, even if the skeleton portion 11 and the coating portion 12 are displaced due to pulsation of blood vessels or the like, the second region 22 of the coating portion 12 can be made less likely to be worn.
Further, when the stent graft 10 is placed in the blood vessel, when the inner wall of the flexible blood vessel is deformed so as to be in close contact with the unevenness of the first region 21 and the second region 22, it is formed between the coating portion 12 and the inner wall of the blood vessel. The contact area becomes large and a large frictional force can be generated.
Therefore, by providing the first region 21 and the second region 22 on the outer peripheral surface of the film portion 12, the friction when the stent graft 10 is in close contact with the inner wall of the blood vessel can be increased. As a result, it is possible to prevent the stent graft 10 from being displaced from a predetermined position in the blood vessel.
　以上、本発明は上記実施形態に限定されることなく、本発明の趣旨を逸脱しない範囲において、種々の改良並びに設計の変更を行ってもよい。 As described above, the present invention is not limited to the above embodiment, and various improvements and design changes may be made without departing from the spirit of the present invention.
　上記実施形態では、骨格部１１は、皮膜部１２に縫い付けられるようにしたが、一例であってこれに限られるものではなく、例えば、テープによる貼着、接着又は溶着等により皮膜部１２に取り付けられていてもよい。
　また、皮膜部１２は骨格部１１の外周側に配置されてもよく、骨格部１１を外側と内側から挟み込むようにして２つの皮膜部１２の間に骨格部１１を配置してもよい。 In the above embodiment, the skeleton portion 11 is sewn to the film portion 12, but the present invention is not limited to this, and the skeleton portion 11 is attached to the film portion 12 by, for example, sticking, adhering, or welding with tape. It may be attached.
Further, the film portion 12 may be arranged on the outer peripheral side of the skeleton portion 11, or the skeleton portion 11 may be arranged between the two film portions 12 so as to sandwich the skeleton portion 11 from the outside and the inside.
　また、上記実施形態で例示した皮膜部１２における第１の領域２１および第２の領域２２の寸法や配置（図３参照）は、一例であってこれに限定されるものではない。例えば、個々の第１の領域２１の形状は、例えば、多角形、楕円などの任意の形状としてもよい。
　皮膜部１２における第１の領域２１の配置パターンは、例えば格子状などの他のパターンであってもよい。また、上記実施形態で例示した皮膜部１２における第１の領域２１と第２の領域２２の位置関係を入れ替えるようにしてもよい。 Further, the dimensions and arrangement (see FIG. 3) of the first region 21 and the second region 22 in the film portion 12 illustrated in the above embodiment are merely examples and are not limited thereto. For example, the shape of each first region 21 may be any shape such as a polygon or an ellipse.
The arrangement pattern of the first region 21 in the film portion 12 may be another pattern such as a grid pattern. Further, the positional relationship between the first region 21 and the second region 22 in the film portion 12 illustrated in the above embodiment may be exchanged.
　また、例えば、図５に示すように、皮膜部１２の外周面において、骨格部１１の形状に対応するようにジグザグ状に折り返すパターンで複数の第１の領域２１を形成し、これら複数の第１の領域２１に沿うように骨格部１１を取り付けてもよい。 Further, for example, as shown in FIG. 5, a plurality of first regions 21 are formed on the outer peripheral surface of the film portion 12 in a zigzag shape so as to correspond to the shape of the skeleton portion 11, and the plurality of first regions 21 are formed. The skeleton portion 11 may be attached along the region 21 of 1.
　上記実施形態のように骨格部１１を皮膜部１２に縫い付ける場合には、皮膜部１２が擦れやすい縫い目の部分に第１の領域２１を設けてもよい。例えば、皮膜部１２の外周面において、縫い目の多い骨格部１１の折り返し部分の位置に第１の領域２１を設けると、皮膜部１２の擦れを効果的に抑制できる。一方、縫い目の部分に第２の領域２２を設けてもよく、この場合には、第２の領域２２の表面と骨格部１１の内側の間での接触面積の確保をより適正に行うことができ、骨格部１１と皮膜部１２の位置ずれを効果的に抑制できる。 When the skeleton portion 11 is sewn to the film portion 12 as in the above embodiment, the first region 21 may be provided at the seam portion where the film portion 12 is easily rubbed. For example, if the first region 21 is provided at the position of the folded portion of the skeleton portion 11 having many seams on the outer peripheral surface of the film portion 12, the rubbing of the film portion 12 can be effectively suppressed. On the other hand, the second region 22 may be provided in the seam portion, and in this case, the contact area between the surface of the second region 22 and the inside of the skeleton portion 11 can be more appropriately secured. Therefore, the misalignment between the skeleton portion 11 and the coating portion 12 can be effectively suppressed.
　加えて、今回開示された実施形態は、全ての点で例示であって制限的なものではないと考えられるべきである。本発明の範囲は、上記した説明ではなくて特許請求の範囲によって示され、特許請求の範囲と均等の意味及び範囲内での全ての変更が含まれることが意図される。 In addition, the embodiments disclosed this time should be considered to be exemplary in all respects and not restrictive. The scope of the present invention is shown not by the above description but by the scope of claims, and is intended to include all modifications within the meaning and scope equivalent to the scope of claims.
１０　　ステントグラフト（管状治療具）
１０Ａ　本体部
１１　　骨格部
１２　　皮膜部
１３　　糸
２１　　第１の領域（表面処理部）
２２　　第２の領域 10 Stent graft (tubular treatment tool)
10A Main body 11 Skeleton 12 Coating 13 Thread 21 First region (surface treatment)
22 Second area

Claims (4)

  1. 　管状の本体部を備える管状治療具であって、
    　前記本体部は、繊維の織物からなる皮膜部と、前記皮膜部の一面に設けられる骨格部と、を有し、
    　前記皮膜部の前記一面には、前記織物の表面が凹凸になるように加工された表面処理部が部分的に設けられている管状治療具。     A tubular treatment tool with a tubular body
    The main body portion has a film portion made of a woven fiber and a skeleton portion provided on one surface of the film portion.
    A tubular treatment tool in which a surface treatment portion processed so that the surface of the woven fabric becomes uneven is partially provided on the one surface of the coating portion.
  2. 　前記表面処理部は、前記皮膜部の一面に間隔を空けて複数設けられる請求項１に記載の管状治療具。 The tubular treatment tool according to claim 1, wherein a plurality of the surface treatment portions are provided on one surface of the coating portion at intervals.
  3. 　前記表面処理部は、前記骨格部の位置を基準として前記一面に設けられている請求項１に記載の管状治療具。 The tubular treatment tool according to claim 1, wherein the surface treatment portion is provided on one surface of the surface with reference to the position of the skeleton portion.
  4. 　管状の本体部を備える管状治療具用膜体であって、
    　前記本体部は、繊維の織物からなる皮膜部を有し、
    　前記皮膜部において管状治療具の骨格部が設けられる一面には、前記織物の表面が凹凸になるように加工された表面処理部が部分的に設けられている管状治療具用膜体。

          A membrane body for a tubular therapeutic tool having a tubular body,
    The main body has a film portion made of a woven fiber and has a film portion.
    A membrane body for a tubular treatment tool in which a surface treatment portion processed so that the surface of the woven fabric is uneven is partially provided on one surface of the film portion where the skeleton portion of the tubular treatment tool is provided.
PCT/JP2020/010704 2019-03-26 2020-03-12 Tubular therapeutic tool and film for tubular therapeutic tool WO2020195870A1 (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800089B1 (en) * 2000-05-31 2004-10-05 Advanced Cardiovascular Systems, Inc. Mechanical attachment method of cover materials on stents
JP2008505728A (en) * 2004-07-12 2008-02-28 ボストン サイエンティフィック リミテッド Composite vascular graft comprising a bioactive agent coating and a biodegradable sheath
JP2010515545A (en) * 2007-01-11 2010-05-13 ロバート ラマール ジュニア ビョーク Multidrug-eluting coronary stent for percutaneous coronary intervention

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800089B1 (en) * 2000-05-31 2004-10-05 Advanced Cardiovascular Systems, Inc. Mechanical attachment method of cover materials on stents
JP2008505728A (en) * 2004-07-12 2008-02-28 ボストン サイエンティフィック リミテッド Composite vascular graft comprising a bioactive agent coating and a biodegradable sheath
JP2010515545A (en) * 2007-01-11 2010-05-13 ロバート ラマール ジュニア ビョーク Multidrug-eluting coronary stent for percutaneous coronary intervention

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