WO2020166744A1

WO2020166744A1 - Skin lifting method using microneedle having deformed structure and skin dressing pad

Info

Publication number: WO2020166744A1
Application number: PCT/KR2019/001858
Authority: WO
Inventors: 이진우
Original assignee: 주식회사 하이로닉
Priority date: 2019-02-15
Filing date: 2019-02-15
Publication date: 2020-08-20

Abstract

The present invention relates to a skin lifting method using a microneedle having a deformed structure and a skin dressing pad and, more specifically, to a skin lifting method comprising the steps of: attaching the skin dressing pad onto a skin; perforating the skin using the microneedle to remove a part of the skin tissue and injecting a drug for skin lifting into the perforated skin; and closing the perforated skin by the contraction of the skin dressing pad, wherein the microneedle may be a hollow microneedle which has an inwardly curved structure having a ∩-shape.

Description

Skin lifting method using modified structure microneedle and skin dressing pad

The present invention relates to a skin lifting method using a deformable structure needle, and more specifically, a skin lifting procedure that removes a part of skin tissue by perforating the skin, and a hollow type having a structure curved in a ∩ shape inward. It relates to a method of performing using a microneedle.

Improvement of excessive skin tissue and skin sagging caused by aging is a worldwide concern, and the demand for skin lifting procedures is increasing due to the continuous growth and aging of the beauty market.

The most effective skin lifting procedure is to remove the actual skin tissue. However, surgical therapy (facial, forehead, chest lift surgery, etc.) may have side effects.

For example, the face may become asymmetric after surgery. Inflammation may result, taking antibiotics or facial nerve palsy.

Accordingly, there is a need for a device that has a fast recovery period and is effective in improving skin sagging, such as some invasive but non-invasive therapy.

A procedure to meet these demands is a method of skin lifting procedure, and refers to a procedure in which unnecessary skin tissue is removed multiplexedly at once in a micro unit without scars or surgery using a microneedle.

Specifically, in the above-described procedure, first, a needle is penetrated into a skin target area, and the skin tissue of the pierced area is removed. In addition, by injecting a drug into the area where the skin tissue has been removed and then shielding it, it is a procedure that internally induces skin regeneration, thereby increasing skin elasticity.

However, when the needle penetrates the skin, it may be difficult to penetrate due to the fold of the skin, the skin tissue removal site may be uneven, and bleeding may occur due to the skin tissue removal. Accordingly, there is a demand for a skin lifting method using a deformable structure needle capable of easily penetrating the skin.

The present invention provides a skin lifting method using a microneedle having a structure curved in a ∩-shape in order to facilitate skin perforation in a skin lifting procedure using a microneedle.

The present invention provides a skin lifting method using a skin dressing pad capable of helping regeneration of perforated skin in a skin lifting procedure using a microneedle.

The skin lifting method using the modified structure microneedle and the skin dressing pad according to the present invention includes the steps of adhering the skin dressing pad to the skin, and the skin is punctured using the microneedle to remove part of the skin tissue, and the punctured Including the step of injecting a drug for skin lifting into the skin and closing the perforated skin while the skin dressing pad is contracted, the microneedle is a hollow microneedle having a structure curved inwardly in a ∩ shape. It can be a needle.

According to an embodiment of the present invention, the microneedle may have a horizontal axis and a vertical axis formed in a ratio of 1 to 2, respectively.

According to an embodiment of the present invention, the microneedles may have an inclination of 24 degrees.

According to an embodiment of the present invention, the skin dressing pad covers the skin so as to facilitate the perforation of the skin by the microneedles to flatten the skin surface, and to close the skin perforated by the microneedles. For example, it may include a contraction layer for contracting the skin surface, and an adhesive layer for bonding the skin support layer and the contraction layer to the skin.

According to an embodiment of the present invention, the skin dressing pad may further include a hemostatic layer for stopping bleeding that occurs when the skin is punctured by the microneedles.

According to an embodiment of the present invention, the shrinking layer may include a stimulus sensitive material capable of shrinking according to a change in temperature or moisture content.

According to an embodiment of the present invention, the skin support layer may be interposed between the contraction layer and the adhesive layer.

According to an embodiment of the present invention, the skin support layer is made of an expandable material, and the contraction layer may contract in one direction or in one of a first direction and a second direction perpendicular to each other.

According to the present invention, in a skin lifting procedure using a microneedle, in order to facilitate skin perforation, there is an effect that a skin lifting method using a microneedle having a structure curved inwardly in a ∩ shape can be provided.

According to the present invention, in a skin lifting procedure using a microneedle, it is possible to provide a skin lifting method using a skin dressing pad that can help regeneration of perforated skin.

1 is a view showing a process of using a microneedle and a skin dressing pad according to an embodiment.

2 is a view showing a microneedle according to an embodiment.

3 is another diagram showing a microneedle according to an embodiment.

4 is another diagram showing a microneedle according to an embodiment.

5 is a view showing a side of a microneedle according to an embodiment.

6 is a view showing a perspective view of a skin dressing pad according to an embodiment.

7 is a diagram illustrating a cross-sectional view of a skin dressing pad according to an exemplary embodiment.

Hereinafter, exemplary embodiments will be described in detail with reference to the accompanying drawings. The same reference numerals in each drawing indicate the same members. Various changes may be made to the embodiments described below. The embodiments described below are not intended to be limited to the embodiments, and should be understood to include all changes, equivalents, and substitutes thereto.

The terms used in the examples are used only to describe specific embodiments, and are not intended to limit the embodiments. Singular expressions include plural expressions unless the context clearly indicates otherwise. In the present specification, terms such as "comprise" or "have" are intended to designate the presence of features, numbers, actions, actions, components, parts, or combinations thereof described in the specification, but one or more other features. It is to be understood that the possibility of addition or presence of elements or numbers, actions, actions, components, parts, or combinations thereof is not preliminarily excluded.

Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which the embodiment belongs. Terms such as those defined in a commonly used dictionary should be interpreted as having a meaning consistent with the meaning in the context of the related technology, and should not be interpreted as an ideal or excessively formal meaning unless explicitly defined in this application. Does not.

In addition, in the description with reference to the accompanying drawings, the same reference numerals are assigned to the same components regardless of the reference numerals, and redundant descriptions thereof will be omitted. In describing the embodiments, when it is determined that a detailed description of related known technologies may unnecessarily obscure the subject matter of the embodiments, the detailed description thereof will be omitted, and the embodiments described below may be implemented by a combination of components.

The terms used in the present application are only used to describe specific embodiments, and are not intended to limit the present invention. Singular expressions include plural expressions unless the context clearly indicates otherwise. In the present application, terms such as "comprise" or "have" are intended to designate the presence of features, numbers, steps, actions, components, parts, or combinations thereof described in the specification, but one or more other features. It is to be understood that the presence or addition of elements or numbers, steps, actions, components, parts, or combinations thereof, does not preclude in advance.

Hereinafter, embodiments of the microneedle 20 and the skin dressing pad 100 according to the present invention will be described in detail with reference to the accompanying drawings, and in the description with reference to the accompanying drawings, the same or corresponding components are The same reference numbers are given, and redundant descriptions thereof will be omitted.

As shown in FIG. 1, in the lifting procedure of the lifting skin 10 using a plurality of microneedles 20, the skin dressing pad 100 is first adhered to the skin 10, and the microneedles 20 are attached. The skin 10 is punctured using the skin 10 to remove a part of the tissue, and a drug for lifting is injected. Finally, the skin dressing pad 100 is contracted and the perforated skin 10 is closed. The procedure of regenerating (10) may be performed, and the skin 10 of the person to be treated may be lifted through such a procedure.

At this time, the microneedle 20 serves to perforate the skin to remove part of the tissue of the skin 10, and the skin dressing pad 100 is used to facilitate the perforation of the skin 10 by the microneedle 20. The skin 10 can be supported, bleeding of the perforated area 12 can be stopped, and regeneration of the skin 10 of the perforated area 12 can be promoted.

Hereinafter, each configuration of the microneedle 20 and the skin dressing pad 100 according to the present embodiment will be described in more detail with reference to FIGS. 2 to 6.

As shown in FIG. 2, the microneedle 20 according to the present embodiment may be a hollow microneedle having a structure curved inwardly in a ∩ shape.

In general, since the tip of the needle is formed in a V-shape, when the skin is perforated using the needle, the skin tissue is removed in a V-shape, thereby forming a V-shaped perforated skin.

When lifting, as mentioned above, a drug for lifting is injected into the perforated skin area where a part of the skin tissue has been removed, but there is a limit to injecting a large amount of drugs into the V-shaped perforated skin.

On the contrary, the microneedle 20 of the present invention may be a hollow microneedle having a structure curved inwardly in a ∩ shape, as shown in FIG. 2.

When the microneedle 20 has a structure in which the microneedle 20 is curved inwardly in a ∩ shape as in the present invention, when the skin is punctured using the needle, the skin tissue is removed in a ∩ shape, and the ∩-shaped perforated skin is Is formed.

In this case, compared to the V-shaped perforated skin, it is possible to inject a large amount of the drug, and further, there is an advantage that the administered drug stays in the skin for a longer time. In particular, in the case of v-shaped perforated skin, the drug may flow out from the perforated skin as soon as the microneedles are removed.In the case of ∩-shaped perforated skin, the drug stays at the bottom of both sides. The amount of drug flowing out of the perforated skin can be significantly reduced.

That is, in the case of perforating the skin using a V-shaped needle, it may be difficult to see a smooth lifting effect due to insufficient drug administration as the drug flows out, but the ∩-shaped microneedle 20 of the present invention When the skin is punctured by using, it may function to retain the drug after administration and improve the consistency of administration.

2 to 3, the needle part 30 of the present invention may be formed by including one or more hollow microneedles 20 having a structure curved in a ∩ shape inward, and accordingly It is possible to apply the above effect of the present invention to a large area of skin.

Meanwhile, perforating the skin using the microneedle 20 may mean incision or ablation of the skin.

In this case, incision means cutting, abrasion, destruction or cutting of skin tissue. For example, an incision can cut, wear, or destroy skin tissue or portions thereof, thereby creating one or more holes in the skin area.

In addition, ablation refers to the action of removing skin tissue from the skin area. For example, ablation may remove skin tissue to have a specific structure, thereby creating one or more holes in the skin region, that is, a sound space generated by removal of the tissue.

Accordingly, when the skin is perforated using the microneedle 20 of the present invention, the skin region may include a plurality of cut tissue portions and/or ablated tissue portions (eg, a plurality of holes).

Referring to FIG. 4, a hollow microneedle having a structure curved in a ∩ shape inward according to an embodiment of the present invention may have a horizontal axis and a vertical axis formed in a ratio of 1 to 2, respectively. When the needle structure is formed in a ratio of 1 to 2 on the horizontal axis and the vertical axis as in the present invention, since the horizontal axis is narrower than the vertical axis, skin perforation can not be performed over a large area, thereby preventing the occurrence of scars on the skin epidermal layer. In addition, since the vertical axis is wider than the horizontal axis, there is an advantage that a perforation can be made to the dermal layer of the skin, and accordingly, a drug can be injected deep into the skin.

However, it is only an example that the horizontal axis and the vertical axis each have a ratio of 1 to 2, and it is obvious to include other ratios (eg, 2 to 4, 3 to 6, etc.) that maintain the ratio.

In addition, referring to the side of the microneedle 20 shown in FIG. 5, according to an embodiment of the present invention, the inclination of the microneedle 20 is so that it can be smoothly introduced into the inside of the skin when the skin is punctured. It can be formed to be 24 degrees.

6, a pad 100 for skin dressing according to an embodiment of the present invention is shown. The skin dressing pad 100 may support the skin to facilitate skin perforation by the microneedle 20, prevent bleeding at the perforated portion, and promote skin regeneration at the perforated portion.

First, the skin support layer 110 of the skin dressing pad 100 may be interposed between the contraction layer 130 and the adhesive layer 140. In addition, the skin support layer 110 may be disposed on the lower surface of the hemostatic layer 120.

The skin support layer 110 may cover the skin to facilitate skin perforation using the microneedles 20 to support the skin surface flat. Specifically, the skin support layer 110 may spread the skin evenly so that a predetermined position can be punctured using a plurality of microneedles 20.

As shown in Fig. 1, wrinkles are generated on the skin due to aging and the surface of the skin 10 becomes uneven.The skin support layer 110 is adhered to the surface of the skin 10 to uniformly flatten the surface of the skin 10 Because it can be made, it is possible to perform a perforation procedure more safely and effectively.

The skin support layer 110 may be, for example, a flexible film made of synthetic resin, and has a certain degree of rigidity to maintain the basic shape of a flat sheet, so when the skin support layer 110 is adhered to the skin surface, the skin support layer ( The skin surface may be evenly spread to correspond to the planar shape of 110).

As shown in FIG. 6, the hemostatic layer 120 may be disposed on the upper surface of the skin support layer 110, and react with blood to stop bleeding that occurs during skin perforation.

The hemostatic layer 120 may entirely cover the perforated area 12 of the skin, and contains a hemostatic agent that reacts with blood, so that the blood coagulates to stop bleeding.

In addition, the hemostatic action is possible through the compression of the bleeding area, and thus, some hemostatic effect can be achieved by closing the skin by the contraction layer 130 to be described later.

Meanwhile, although not shown in the drawings, by applying a hemostatic agent to the skin support layer 110, the skin support layer 110 and the hemostatic layer 120 may be integrally formed as one layer. In this case, the skin support layer 110 may be made of an absorbent material capable of absorbing a hemostatic component. In addition, by applying a hemostatic agent to the contraction layer 130 to be described later, the contraction layer 130 and the hemostatic layer 120 may be formed as one layer.

The contraction layer 130 may be closed by contracting the skin surface of the perforated area in order to promote regeneration of the perforated skin.

Specifically, the contraction layer 130 may be formed of a stimulus-sensitive material in which contraction occurs in response to temperature, pH, light, moisture, chemical exposure, electricity, and magnetic fields. In addition, the contraction direction of the contraction layer 130 may be adjusted as necessary.

When the contraction layer 130 contracts according to the temperature change, contraction may occur when the contraction layer 130 reaches a preset temperature. At this time, if the preset temperature is equal to the body temperature, the body temperature when adhered to the skin This can cause contraction. In contrast, when the preset temperature at which the contraction layer 130 contracts is set lower than the body temperature, the contraction layer 130 may reach a preset temperature according to a change in external temperature due to cooling or the like, and contraction may occur.

In addition, when the shrinkage layer 130 shrinks according to a change in moisture content, the shrinkage layer 130 may shrink when moisture included in the shrinkage evaporates. When moisture contained in the shrinking layer 130 evaporates, the volume may be reduced and shrinkage may occur.

The shrinking layer 130 may shrink in one direction. When contraction occurs in one direction, it is possible to provide an effect of lifting the skin in one direction in a skin lifting procedure.

In addition, the contraction layer 130 may contract in a first direction and a second direction perpendicular to each other on a plane. Through this, the first direction and the second direction are combined to cause contraction, thereby providing a tightening effect in all directions on a plane.

In addition, the shrinking layer 130 may be contracted in a direction in which the size of the punctured portion is reduced when puncturing occurs by the microneedle 20. Specifically, when a physical change occurs due to perforation of the microneedle 20, the shrinking layer 130 may shrink in a direction in which the size of the perforated portion is reduced.

For example, when perforation occurs by the microneedle 20, the shrinking layer 130 may shrink only the periphery of the perforated portion 12 to close the perforated portion.

In addition, the contraction layer 130 may contain a collagen component to promote skin regeneration.

Skin regeneration such as EGF (Epidermal Growth Factor) below any one of the above-described adhesive layer 140, skin support layer 110, hemostatic layer 120, and contraction layer 130 in contact with the skin A material that assists in may be applied.

The skin dressing pad 100 of the present invention may be made of a transparent material so that the skin condition can be checked without removing the pad when the skin is attached. On the contrary, the skin dressing pad 100 includes any one of the adhesive layer 140, the skin support layer 110, the hemostatic layer 120, and the contraction layer 130 so that the treatment site is not conspicuous during skin attachment. It can be composed of. In addition, a cover layer made of an opaque flesh-colored material may be further included.

According to an embodiment of the present invention, as shown in FIG. 7, the pad 100 for skin dressing of the present invention includes a hemostatic layer 120, a skin support layer 110, and a contraction layer 130 on the adhesive layer 140. These can be placed sequentially. That is, in the case of this embodiment, unlike the embodiment of FIG. 6, the hemostatic layer 120 may be formed below the skin support layer 110. Therefore, since the hemostatic layer 120 is disposed closer to the skin, it is possible to stably stop bleeding when bleeding occurs due to skin perforation.

As described above, although the embodiments have been described by the limited drawings, various modifications and variations are possible from the above description by those of ordinary skill in the art. For example, the described techniques are performed in a different order from the described method, and/or components such as a system, structure, device, circuit, etc. described are combined or combined in a form different from the described method, or other components Alternatively, even if substituted or substituted by an equivalent, an appropriate result can be achieved. Therefore, other implementations, other embodiments, and equivalents to the claims also fall within the scope of the following claims.

The skin lifting method using the modified structure microneedle and the skin dressing pad according to the present invention can be used in various skin lifting methods.

Claims

In the method of performing skin lifting using a modified structure microneedle and a skin dressing pad,

Adhering the skin dressing pad to the skin;

Piercing the skin using the microneedle to remove part of the skin tissue and injecting a drug for skin lifting into the perforated skin; And

Consisting including; closing the perforated skin while the skin dressing pad is contracted,

The micro-needles are hollow micro-needles having a structure curved inwardly in a ∩-shape.
The method of claim 1,

The microneedle is characterized in that the horizontal axis and the vertical axis are formed in a ratio of 1 to 2, skin lifting method.
The method of claim 1,

A method of performing skin lifting, characterized in that the inclination of the microneedles is formed at 24 degrees.
The method of claim 1,

The skin dressing pad may include a skin support layer covering the skin so as to facilitate perforation of the skin by the microneedles to planarize the skin surface;

A contraction layer that contracts the skin surface to close the skin perforated by the microneedles; And

Characterized in that it comprises an adhesive layer for adhering the skin support layer and the contraction layer to the skin.
The method of claim 4,

The skin dressing pad further comprises a hemostatic layer for stopping bleeding that occurs when the skin is punctured by the microneedles.
The method of claim 4,

The contraction layer comprises a stimulus-sensitive material capable of contraction according to a change in temperature or moisture content.
The method of claim 4,

The skin support layer is interposed between the contraction layer and the adhesive layer, skin lifting performing method.
The method of claim 4,

The skin support layer is made of an expandable material, and the contraction layer is characterized in that contraction occurs in one direction or in one of a first direction and a second direction perpendicular to each other.