WO2020148660A1

WO2020148660A1 - Composition comprising tolfenpyrad and pyraclostrobin

Info

Publication number: WO2020148660A1
Application number: PCT/IB2020/050283
Authority: WO
Inventors: Dr. Shailendra Mitharam BHARAMBE; Pushpender Singh CHOUHAN; Dr. Ashim Kumar DUTTA; Ashutosh ACHARYA; Vishwanath GADE; Santosh Shridhar AUTKAR; Ravikumar Suryanarayana SARAGUR; Ruchi GARG
Original assignee: Pi Industries Ltd.
Priority date: 2019-01-17
Filing date: 2020-01-15
Publication date: 2020-07-23
Also published as: WO2020148660A8; MA54005B1; KR20210116466A; CO2021006225A2; TN2021000134A1; CN113453552A; MX2021006534A; ZA202104998B; MA54005A1

Abstract

The present invention discloses a synergistic combination of tolfenpyrad and pyraclostrobin 5with its composition and a method for controlling a wide variety of undesired pathogenic microorganisms, insect pests and mites, for a plant, including the treatment of plant/plant parts and a region around the plant. The present invention also discloses an enhanced efficacy against pests and diseases in comparison to individual components of the said combination. The combination also widens the spectrum and said to have longer residual effects against undesired pathogenic microorganisms, insect pests and mites.

Description

COMPOSITION COMPRISING TOLFENPYRAD AND PYRACLOSTROBIN

FIELD OF THE INVENTION:

The present invention relates to a combination of tolfenpyrad and pyraclostrobin and its composition and methods of preparation thereof. Particularly, the present invention relates to a synergistic composition comprising tolfenpyrad and pyraclostrobin, methods of preparation of the composition and use thereof for the control of a wide variety of undesired phytopathogenic microorganisms, insect pests and mites.

BACKGROUND OF THE INVENTION:

In many economically important crops, such as rice, peppers, tomatoes, grapes, peas, cotton and other agricultural and horticultural crops, fungal infection and insect infestation may occur simultaneously for which growers are applying control measures either separately or by simply tank mixing various insecticides and fungicides together. This practice of mixing various pesticides might lead to poor efficacy and crop damage due to compatibility issues hence a premix of the best possible formulation for a combination of an insecticide and a fungicide would help growers to combat these important diseases and insects/mites in those crop stages.

Typical problems arising in the field of pest control is to reduce the dose rates of the active ingredients in order to reduce or avoid unfavorable environmental or toxicological effects whilst still allowing effective disease/pest control. Therefore, a combined application of an effective amount of fungicide and insecticide as a uniform composition is a practical necessity.

It is known in the art that certain pyrazole carboxamide derivatives have insecticidal as well as fungicidal properties for example tolfenpyrad. Tolfenpyrad is a contact insecticide and fungicide, which was developed by Mitsubishi Chemical (now Nihon Nohyaku), as described in US 5,039,693. It is used to control or suppress a wide range of insect pests and diseases including Lepidoptera, Coleoptera, Diptera, Hemiptera, Orthoptera, and Thysanoptera insects, and downy mildew and powdery mildew. It is effective in controlling all developmental stages of most target pests. It is classified under group 21A of the IRAC mode of action and group 39 of FRAC mode of action. Tolfenpyrad is a MET1 inhibitor, which inhibits cell respiration when it comes in contact with the target pests.

Chemically, it is 4-chloro-3-ethyl-l-methyl-/V-[4-(p-tolyloxy)benzyl]-l//-pyrazole-5- carboxamide and has the following structure:

Strobilurin derivatives have fungicidal activity, for example, pyraclostrobin, azoxystrobin, fluoxastrobin, trifloxystrobin, pyribencarb, or pyraoxystrobin. Pyraclostrobin is a broad spectrum foliar fungicide, developed by BASF, as described in US 5,869,517. It is classified under group 11 of the FRAC mode of action, which blocks the mitochondrial electron transport and thus inhibits the energy supply of the fungus which results in the death of the target fungus. Currently, it is used to control various fungal diseases such as downy mildew, powdery mildew, black shank, black spot, melanose, post bloom fruit drop, anthracnose, alternaria brown spot, scab or greasy spot, leaf rust, black point, net blotch, scald, septoria leaf and glume blotch, spot blotch, stem rust, stripe rust, yellow leaf spot, eyespot, gray leaf spot, northern corn leaf spot, physoderma brown spot, rust, southern corn leaf blight or yellow leaf blight. Chemically, it is methyl 2-[l-(4-chlorophenyl)-lFl-pyrazol-3-yloxymethyl]-N- methoxycarbanilate and has the following structure:

Various patent applications disclose the mixtures of fungicides and insecticides for e.g. US20120322654, US20080261811 and WO2011144593. There is no such effective composition available that act simultaneously on a wide variety of fungi and pest. It has been found that, as a solution to the above mentioned problems, a combination comprising a pyrazole carboxamide class compound and a strobilurin class compound provides an effective composition in controlling a wide variety of undesired phytopathogenic microorganisms, insect pests and mites. More, specifically, the combination comprises tolfenpyrad and pyraclostrobin.

The components of the combination of the present invention have a similar site of action. Tolfenpyrad acts by inhibiting complex-1 in the mitochondrial electron-transport chain of mitochondria and pyraclostrobin acts by inhibiting the complex-III in mitochondrial respiration. The present invention provides a combination of tolfenpyrad and pyraclostrobin with enhanced efficacy and spectrum as compared to the use of tolfenpyrad and pyraclostrobin alone.

SUMMARY OF THE INVENTION:

In one aspect, the present invention provides a composition comprising of:

a) an effective amount of tolfenpyrad or salt(s) thereof,

b) an effective amount of pyraclostrobin or salt(s) thereof,

c) optionally, an addition of one or more insecticidal or fungicidal or acaricidal or nematicidal or herbicidal or plant growth regulator compounds or any combination thereof,

d) agriculturally acceptable additives.

In a particular aspect, the present invention provides a synergistic combination of tolfenpyrad and pyraclostrobin to control a wide variety of undesired phytopathogenic microorganisms, insect pests and mites.

In another aspect, the present invention provides a synergistic fungicidal and insecticidal combination of tolfenpyrad and pyraclostrobin.

In yet another aspect, the present invention provides a synergistic fungicidal combination of tolfenpyrad and pyraclostrobin. In a further aspect, the present invention provides a synergistic insecticidal combination of tolfenpyrad and pyraclostrobin.

In another aspect, the present invention is to provide longer residual control of the undesired phytopathogenic microorganisms, insect pests and mites treated with the combination of tolfenpyrad and pyraclostrobin.

In a further aspect, the present invention provides a synergistic composition comprising of: a) an effective amount of tolfenpyrad or salt(s) thereof,

b) an effective amount of pyraclostrobin or salt(s) thereof,

d) agriculturally acceptable additives.

In one aspect, the present invention provides a synergistic composition of tolfenpyrad and pyraclostrobin to control a wide variety of undesired phytopathogenic microorganisms, insect pests and mites.

In a further aspect, the present invention provides a synergistic composition comprising tolfenpyrad and pyraclostrobin; the composition possesses fungicidal and/or insecticidal activity.

In another aspect, the present invention provides a method for the preparation of the composition comprising of tolfenpyrad and pyraclostrobin.

In a further aspect, the present invention provides a method for improving crop health (phyto tonic effect), comprising treating a plant with an effective amount of the composition of tolfenpyrad and pyraclostrobin.

The above aspects and other objectives will become more apparent in view of the description given below. DETAILED DESCRIPTION OF THE INVENTION:

ABBREVIATIONS

DEFINITIONS

The foregoing definitions provided herein for the terminologies used in the present disclosure are for illustrative purposes only and in no manner limit, the scope of the present invention disclosed in the present disclosure.

It will be understood that the terminology used herein is for the purpose of describing embodiments only, and is not intended to be limiting. As used in this specification, the singular forms“a”,“an” and“the” include plural referents unless the context clearly dictates otherwise. Thus, for example, the reference to“a surfactant” includes one or more such surfactants.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the invention pertains. Although other methods and materials similar, or equivalent, to those described herein can be used in the practice of the present invention, the preferred materials and methods are described herein. As used herein, the terms“comprises”,“comprising”,“includes”,“including”, or any other variation thereof, are intended to cover a non-exclusive inclusion, subject to any limitation explicitly indicated. For example, a composition or a method that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, or method.

As used herein, the term“composition” or“formulation” can be used interchangeably, unless stated otherwise, is meant to encompass, and are not limited to, compositions or formulations containing the combination of tolfenpyrad and pyraclostrobin.

As used herein, the term“insecticidal” refers to the ability of a composition or substance to improve the ability of insect mortality or inhibit the growth rate.

As used herein the term“fungicidal” refers to the ability of a composition or substance to reduce the rate of fungal growth or increase fungal mortality.

As used herein the term“nematicidal” refers to the ability of a composition or substance to improve the ability of the nematode mortality or inhibit the growth rate.

As used herein the term“acaricidal” refers to the ability of a composition or substance belonging to the Arachnida increase mortality ectoparasites Acari or its ability to inhibit the growth rate.

As used herein the term“herbicidal”, refers to the ability of a composition or substance that is applied to an area of interest (eg, a field or area of cultivation) before the plants appear visibly from the soil and / or before germination of the seeds or that is applied to an area after a plant has visibly emerged from the soil.

As used herein the term“plant growth regulator” refers to the ability of a composition or substance that serves to modify the growth and development of a treated plant to an agricultural maturity state without killing the treated plant.

As used herein, the term“additive(s)” or“auxiliary agent(s)” or“agriculturally acceptable carrier(s)” can be used interchangeably and refers to inert substances which are commonly used as diluent, to provide stability or to increase the activity profile of the composition or formulation with or without having agrochemical activity or direct effect on the undesired pathogenic microorganism, insect pests and mites.

As used herein, the term“surfactant(s)” means a compound that, when dissolved in a liquid, reduces the surface tension of the liquid, which reduces the interfacial tension between two liquids or which reduces surface tension between a liquid and a solid.

As used herein, the term“stabilize^ s)” refers to a substance capable of imparting resistance against physical or chemical deterioration or deformulation.

As used herein, the term“defoamer(s)” refers to a chemical additive that reduces and hinders the formation of foam in the industrial process of liquids, semi-solids, or solids. The terms defoamer, defoaming agent and anti-foaming agent can be used interchangeably.

As used herein, the term“thickener(s)” refers to a polymeric material, which at a low concentration increases the viscosity of an aqueous solution and helps to stabilize the composition.

Unless otherwise specified, % refers to % weight; and % weight refers to % of the weight of respective component with respect to the total weight of the composition.

As used herein, the term“locus” means a plant, plant parts, plant propagation material (preferably seed), soil, area, material or environment in which a pest is growing or may grow. As used herein, the term“plant parts” are understood to mean all above-ground and below ground parts and organs of plants, such as shoot, leaf, flower and root, examples including leaves, needles, stems, stalks, flowers, fruit-bodies, fruits and seeds, and also roots, tubers and rhizomes. The plant parts also include harvested plants and vegetative and generative propagation material, for example seedlings, tubers, rhizomes, cuttings and seeds.

As used herein, the term“effective amount” means the amount of the active substances in the compositions to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target organism. The effective amount can vary for the various compositions used in the present invention. An effective amount of the compositions will also vary according to the prevailing conditions such as desired pesticidal effect and duration, weather conditions, target species, locus, mode of application, and the like.

As used herein, the term “tolfenpyrad” encompasses tolfenpyrad or its agrochemical acceptable salt(s), ester(s), derivative(s) or any other modified form of tolfenpyrad.

As used herein, the term“pyraclostrobin” encompasses pyraclostrobin or its agrochemical acceptable salt(s), ester(s), derivative(s) or any other modified form of pyraclostrobin.

In one embodiment, the present invention provides a composition comprising of:

a) an effective amount of tolfenpyrad or salt(s) thereof,

b) an effective amount of pyraclostrobin or salt(s) thereof,

d) agriculturally acceptable additives.

In another embodiemnt, the present invention provides a synergistic composition comprising of:

a) an effective amount of tolfenpyrad or salt(s) thereof,

b) an effective amount of pyraclostrobin or salt(s) thereof,

d) agriculturally acceptable additives.

In one embodiment, the present invention provides a synergistic combination of tolfenpyrad and pyraclostrobin to control a wide variety of undesired phytopathogenic microorganisms, insect pests and mites.

In a further embodiment, the present invention provides a fungicidal and insecticidal combination of tolfenpyrad and pyraclostrobin. In yet another embodiment, the present invention provides a fungicidal combination of tolfenpyrad and pyraclostrobin.

In a further embodiment, the present invention provides an insecticidal combination of tolfenpyrad and pyraclostrobin.

In another embodiment, the present invention provides a longer residual control of the undesired phytopathogenic microorganisms, insect pests and mites treated with the combination of tolfenpyrad and pyraclostrobin.

The combination ratio of tolfenpyrad and pyraclostrobin depends on various factors such as, the undesired phytopathogenic microorganisms, insect pests and mites to be controlled, the degree of infestation, the climatic conditions, the characteristics of the soil and the application method, wherein the ratio of tolfenpyrad and pyraclostrobin is 50:1 to 1:50, preferably 20:1 to 1: 20 or 10: 1 to 1: 10, more preferably 3:2 to 2:3.

In one embodiment, the present invention further provides a composition of tolfenpyrad and pyraclostrobin for the control of a wide variety of undesired phytopathogenic microorganisms, insect pests and mites.

In another embodiment, the present invention provides a composition of tolfenpyrad and pyraclostrobin, wherein the composition is used as fungicidal and/or insecticidal composition. The composition is selected from wettable powder (WP), a water dispersible granule (WDG), a water dispersible tablet (WT), a suspension concentrate (SC), an ultra-low volume (ULV) liquid (UL), an ultra-low volume (ULV) suspension (SU), an emulsifiable granule (EG), an oil-in-water emulsion (EW), an emulsifiable concentrate (EC), an emulsifiable powder (EP), a dispersible concentrate (DC), a micro-emulsion (ME), an oil dispersion (OD), a capsule suspension (CS), a dustable powder (DP) or an aerosol (AE).

In a preferred embodiment, the present invention provides a water dispersible granule composition of tolfenpyrad and pyraclostrobin.

In another preferred embodiment, the present invention provides a suspension concentrate composition of tolfenpyrad and pyraclostrobin. These compositions may be manufactured by any process known in the art, such as, “Pesticide Formulation Guide” (edited by Pesticide Science Society of Japan, The Agricultural Formulation and Application Committee, published by Japan Plant Protection Association, 1997).

The composition of the present invention comprises of tolfenpyrad and pyraclostrobin in a wider ratio, in relation to various factors such as, the undesired phytopathogenic microorganisms, insect pests and mites to be controlled, the degree of infestation, the climatic conditions, the characteristics of the soil and the application method, wherein the weight ratio of tolfenpyrad and pyraclostrobin is 50: 1 to 1 :50, preferably 20: 1 to 1 : 20 or 10: 1 to 1 : 10, more preferably 3:2 to 2:3.

Accordingly, the present invention further provides a composition for the control of a wide variety of undesired phytopathogenic microorganisms, insect pests and mites, wherein the weight percentage of tolfenpyrad is about 4% to 80%, preferably about 10% to 60% and the weight percentage of pyraclostrobin is 80% to 4%, preferably about 60% to 10% and the weight percentage of additives is about 5% to 95%, preferably about 20% to 90%. The total content of tolfenpyrad and pyraclostrobin in the composition is selected in the weight range typically from 8% to 84%, preferably from 10% to 80%, more preferably from 12% to 75%.

The composition comprising organic or inorganic carrier material including agriculturally acceptable additive(s) is selected from the group comprising of solid carrier(s), liquid carrier(s), gaseous carrier(s), surfactant(s), binder(s), disintegrating agent(s), pH adjuster(s), thickener(s), preservative(s), anti-freezing agent(s), defoaming agent(s), extender(s), stabilizer(s) and/or coloring agent(s) or a combination thereof. The composition may also contain if desired, one or more auxiliaries customary for crop protection compositions.

Solid carrier(s) is selected from the group comprising of, but not limited to, natural minerals quartz, talc, kaolin, pyrophyllite, montmorillonite, attapulgite, bentonite, chalk, zeolite, calcite, sericite, acid clay, diatomaceous earth, Fuller’s earth, meerschaum, gibbsite, dolomite or pumice; synthetic minerals such as precipitated silica, fumed silica, sodium silicate, alumina, aluminum hydroxide; inorganic salts such as calcium carbonate, ammonium sulfate, sodium sulfate, potassium chloride, organic materials such as urea, solid polyoxyethylene, solid polyoxypropylene, polyethylene, polypropylene, lactose, starch, lignin, cellulose, cottonseeds hulls, wheat flour, soyabean flour, wood flour, walnut shell flour, plant powders, sawdust, coconut shellflower, corn cob, tobacco stem. These solid carriers may be used alone or in combination.

Liquid carrier(s) is selected from the group comprising of, but not limited to, water; alcohols such as ethanol, propanol, butanol, n-octanol, isopropanol ethylene glycol, diethylene glycol, propylene glycol, polyethylene glycol, benzyl alcohol, glycerin; polyol ethers such as ethylene glycol monopropyl ether, diethylene glycol monomethyl ether, dipropylene glycol dimethyl ether; ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone; ethers such as dipropyl ether, dioxane, tetrahydrofuran, aliphatic hydrocarbons such as normal paraffin, isoparaffin, kerosene, mineral oil; aromatic hydrocarbons such as xylene, toluene, naphthene, solvent naphtha, solvent C9, solvent C10, solvent C12, solvesso 100, solvesso 150, solvesso 200; chlorinated aliphatic or aromatics hydrocarbons such as chlorobenzene, chloroethylene, methylene chloride; esters such as ethyl acetate, diisopropyl phthalate, dimethyl adipate, methyl oleate, methyl tallowate; lactones such as gamma-butyrolactone, gamma-valerolactone, epsilon-caprolactone; amides such as dimethylformamide, N-methylpyrrolidone, N-octylpyrolidone, N,N-dimethyldecanamide; nitriles such as acetonitrile; organosulfur compound such as dimethyl sulfoxide; vegetable oils such as soybean oil, rapeseed oil, cotton seed oil. These liquid carriers may be used alone or in combination.

Gaseous carrier(s) is selected from the group comprising of, but not limited to, liquefied petroleum gas, air, nitrogen, carbon dioxide or dimethyl ether. These gaseous carriers may be used alone or in combination thereof.

Surfactant(s) (a dispersing agent, a wetting agent, a spreader, an adjuvant for penetration enhancement, rain fastness, soil leaching control etc.) are nonionic or anionic surfactants or a combination of these surfactants. It is preferred to use one or more than one kind of surfactant. Surfactant(s) is selected from the group comprising of, but not limited to, sugar esters such as sorbitan monolaurate, polyoxyethylene sorbitan monolaurate; alkyl polyglucoside such as decyl glucoside; polyoxyethylene alkyl ethers such as polyoxyethylene lauryl ether, or polyoxyethylene coconut fatty alcohol ether; polyoxyethylene alkynyl ether such as polyoxyethylene 2,4,7,9-tetramethyl-5-decyn-4,7-diol ether; polyoxyethylene aryl ethers such as polyoxyethylene nonylphenyl ether or polyoxyethylene tristyrylphenyl ether; polyoxyethylene vegetable oil ethers such as polyoxyethylene castor oil or polyoxyethylene hydrogenated castor oil; vegetable oil ethoxylate; alcohol C12-C15 ethoxylate; polyoxyethylene fatty acid esters such as polyoxyethylene monolaurate, polyoxyethylene distearate or polyoxyethylene resin acid ester; polyoxyethylene polyoxypropylene (EO-PO) block co-polymers such as Pluronic^®; polyoxyethylene polyoxypropylene alkyl ether such as polyoxyethylene polyoxypropylene lauryl ether; polyoxyethylene polyoxypropylene aryl ether such as polyoxyethylene polyoxypropylene styrylphenyl ether; polyoxyethylene alkyl amines such as polyoxyethylene stearyl amine; polyoxyethylene fatty acid amide such as lauric acid diethanolamid; fluorinated surfactant; alkyl sulfates such as sodium lauryl sulfate; sodium alkylbenzene sulfonate, calcium alkylbenzene sulphonate; polyoxyethylene alkyl ether sulfates such as sodium polyoxyethylene lauryl ether sulfate; polyoxyethylene aryl ether sulfates such as sodium polyoxyethylene nonylphenyl ether sulfate or ammonium polyoxyethylene tristyrylphenyl ether sulfate; aryl sulfonate such as calcium dodecyl benzene sulfonate, sodium naphthalene sulfonate or sodium naphthalene sulfonate formaldehyde condensate; poly aryl phenyl ether sulphate ammonium salt;‘alpha’ -olefin sulfonate; alkyl sulfosuccinate such as sodium dioctyl sulfosuccinate; sodium lignosulfonate; polycarboxylic acid sodium salt; N-methyl fatty acid sarcosinate; polyoxyethylene alkyl ether phosphate; polyoxyethylene aryl ether phosphates such as polyoxyethylene phenyl ether phosphate; polyoxyethylene alkyl phenyl ether phosphate; graft co-polymers such as polymethyl methacrylate-polyethylene glycol graft copolymer; or a combination thereof.

Binder(s) or adhesive-imparting agent(s) is selected from the group comprising of, but not limited to, polyvinyl alcohol, dextrin, denatured dextrin, soluble starch, guar gum, xanthan gum, sucrose, polyvinylpyrrolidone, gum arabic, polyvinyl acetate, sodium polyacrylate, carboxymethyl cellulose or its salt, carboxymethylcellulose dextrin, bentonite, polyethylene glycol having an average molecular weight of 6,000 to 20,000, polyethylene oxide having average molecular weight of 100,000 to 5,000,000, natural phosphatide such as cephalinic acid or lecithin. These binders or adhesive -imparting agents may be used alone or in combination thereof.

Disintegrating agent(s) is selected from the group comprising of, but not limited to, sodium tripolyphosphate, stearic acid metal salt, cellulose powder, dextrin, methacrylate co-polymer, polyvinylpyrrolidone, polyaminocarboxylic acid chelate compound, styrene sulfonate/isobutylene/maleic anhydride co-polymer, starch/polyacrylonitrile graft co- polymer, sodium hexametaphosphate, carboxymethyl cellulose, sodium polycarbonate, bentonite. These disintegrating agents may be used alone or in combination thereof. pH adjuster(s) is selected from the group comprising of, but not limited to, sodium or potassium carbonate, sodium or potassium hydrogen carbonate, sodium or potassium dihydrogenphosphate, disodium or dipotassium hydrogenphosphate, citric acid, malic acid and triethanolamine. These pH adjusters may be used alone or in combination thereof.

Thickener(s) is selected from the group comprising of, but not limited to, water-soluble polymer and inorganic fine powder, wherein the examples for water-soluble polymers are xanthan gum, welan gum, guar gum, polyvinyl alcohol, carboxymethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic polymer, acrylic graft copolymer, starch derivative or polysaccharide; or an inorganic fine powder selected from high purity silica, bentonite, white carbon. These thickeners may be used alone or in combination thereof.

Preservative(s) is selected from the group comprising of, but not limited to, potassium sorbate, 4-hydroxybenzoic acid esters, 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4- isothiazolin-3-one, 1 ,2-benzisothiazolin-3-one (Proxel^® GXL). These preservatives may be used alone or in combination thereof.

Anti-freezing agent(s) is selected from the group comprising of, but not limited to, polyhydric alcohol such as ethylene glycol, diethylene glycol, propylene glycol, polyethylene glycol and glycerol. These anti-freezing agents may be used alone or in combination thereof.

Defoamer(s) is selected from the group comprising of, but not limited to, silicone compounds such as polysiloxane, polydimethylsiloxane and organic fluorine compounds. These defoamers may be used alone or in combination thereof.

Extender(s) is selected from the group comprising of, but not limited to, silicon type surfactant, a cellulose powder, dextrin, processed starch, a polyaminocarboxylic acid chelate compound, crosslinked polyvinylpyrrolidone, maleic acid and styrene, methacrylic acid co polymer, half ester of polymer of polyhydric alcohol with dicarboxylic anhydride, water- soluble salt of polystyrene sulfonic acid. These extenders may be used alone or in combination thereof. Stabilizer(s) is selected from the group comprising of, but not limited to, drying agents such as zeolite, quick lime or magnesium oxide; antioxidant agent such as phenol type, amine type, sulfur type or phosphorus type; or ultraviolet absorber such as salicylic acid type or a benzophenone type. These stabilizers may be used alone or in combination thereof.

Coloring agent(s) is selected from the group comprising of, but not limited to inorganic pigment such as iron oxide, titanium oxide or Prussian blue; organic dye such as alizarin dye, azo dye, metal phthalocyanine dye. These coloring agents may be used alone or in combination thereof.

When additive ingredients are incorporated into the composition of the present invention, the content of the carrier is selected typically in weight range of about 5% to 95%, preferably about 20% to 90%; the content of the surfactant is selected from the range of typically about 0.1% to 30%, preferably about 0.5% to 10%, and the content of the other additives is selected from the range of typically about 0.1% to 30%, preferably about 0.5% to 10%.

The composition of the present invention can be applied by any one of the methods selected from atomization, spreading, dusting, spraying, diffusion, immersion, irrigation, injection, mixing, sprinkling (water immersion), foaming, dressing, coating, blasting, fumigation, smoking, smog and painting.

In an embodiment, the present invention provides a method of controlling a wide variety of undesired phytopathogenic microorganisms, insect pests and mites, with an effective amount of a composition of tolfenpyrad and pyraclostrobin.

In an embodiment, the present invention provides a method for controlling undesired phytopathogenic microorganisms with an effective amount of the composition of tolfenpyrad and pyraclostrobin.

The undesired pathogenic microorganism for the present invention is selected from the group comprising of Albugo spp. (white rust) on ornamentals, vegetables (e.g. A. Candida) and sunflowers (e.g. A. tragopogonis), Altemaria spp. (Alternaria leaf spot) on vegetables, citrus fruits (A. citri), rape (A. brassicola or brassicae), sugar beets (A. tenuis), fruits, rice, soybeans, potatoes (e.g. A. solani or A. altemata), tomatoes (e.g. A. solani or A. alternata) and wheat; Aphanomyces spp. on sugar beets and vegetables; Ascochyta spp. on cotton, cereals and vegetables, e.g. A. tritici (anthracnose) on wheat and A. hordei on barley; Bipolaris and Drechslera spp. (teleomorph: Cochliobolus spp. for e.g. Cochliobolus carbonum (northern corn leaf blight)), e.g. Southern leaf blight (D. maydis ) or Northern leaf blight ( B . zeicola ) on corn, e.g. spot blotch (B. sorokiniand) on cereals, e.g. B. oryzae on rice and turfs and on oats; Blumeria (formerly Erysiphe ) graminis (powdery mildew) on cereals (e.g. on wheat or barley); Botrytis cinerea (teleomorph: Botryo tinia fit eke I iana : grey mold) on fruits and berries (e.g. strawberries), vegetables (e.g. lettuce, carrots, celery and cabbages), rape, flowers, vines, forestry plants and wheat; Bremia lactucae (downy mildew) on lettuce; Ceratocystis (syn. Ophiostomd) spp. (rot or wilt) on broadleaved trees and evergreens, e.g. C. ulmi (Dutch elm disease) on elms; Cercospora spp. (Cercospora leaf spots) on corn and cotton, (Cercospora blight spots) on cotton, (e.g. Gray leaf spot: C. zeae-maydis ), rice, sugar beets (e.g. C. beticola), sugar cane, vegetables, coffee, soybeans (e.g. C. sojina or C. kikuchii ) and rice, sunflower (e.g. cercospora leaf spot: C. helianthi), peanut (e.g. early leaf spot: C. arachidicola), Cercosporidium spp. on peanut (e.g. C. personation: late leaf spot); Cladosporium spp. on tomatoes (e.g. C. fulvum: leaf mold) and cereals, e.g. C. herbarum (black ear) on wheat, C. caryigenum (pecan scab) on pecan; Cylindrocladium spp. on peanut (C. crotalariae: cylindrocladium black rot); Claviceps purpurea (ergot) on cereals; Cochliobolus (anamorph: Helminthosporium of Bipolaris ) spp. (leaf spots) on corn (C. carbonum), cereals (e.g. C. sativus (black point), anamorph: B. sorokiniand) and rice (e.g. C. miyabeanus, anamorph: H. oryzae), Colletotrichum (teleomorph: Glomerella) spp. (anthracnose) on cotton (e.g. C. gossypii), corn (e.g. C. graminicola: Anthracnose stalk rot), soft fruits, potatoes (e.g. C. coccodes: black dot), beans (e.g. C. Iindemuthianum), citrus fruits (e.g. C. acutatum (post bloom fruit drop), C. gloeosporioides) and soybeans (e.g. C. truncatum or C. gloeosporioides), Corticium spp., e.g. C. sasakii (sheath blight) on rice; Corynespora cassiicola (leaf spots) on soybeans and ornamentals; Cycloconium spp., e.g. C. oleaginum on olive trees; Cylindrocarpon spp. (e.g. fruit tree canker or young vine decline, teleomorph: Nectria or Neonectria spp.) on fruit bees, vines (e.g. C. liriodendri, teleomorph: Neonectria liriodendri: Black Foot Disease) and ornamentals; Dematophora (teleomorph: Rosellinia) necatrix (root and stem rot) on soybeans; Diplodia spp. e.g. Diplodia boll rot on cotton, Diaporthe spp., e.g. D. phaseolorum (damping off) on soybeans, D. citri (melanose) on citrus fruits; Drechslera (syn. Helminthosporium, teleomorph: Pyrenophora) spp. on corn, cereals, such as barley (e.g. D. teres, net blotch), oats (e.g. D. avenae, leaf spot), and wheat (e.g. D. tritici-repentis: tan spot), rice and turf; Esca (dieback, apoplexy) on vines, caused by Formitiporia (syn. Phellinus ) punctata, F. mediterranea, Phaeomoniella chlamydospora (earlier Phaeoacremonium chlamydosporum ), Phaeoacremonium aleophilum and/or Botryosphaeria obtusa Elsinoe spp. on pome fruits (E. pyri), on citrus fruits (E. fawcetti ), soft fruits (E. veneta : anthracnose) and vines (E. ampelina : anthracnose); Entyloma oryzae (leaf smut) on rice; Epicoccum spp. (black mold) on wheat; Erysiphe spp. (powdery mildew) on sugar beets (E. betae), (powdery mildew) on rye (E. graminis), vegetables (e.g. E. pisi ), such as cucurbits (e.g. E. cichoracearum), cabbages, sunflower, rape (e.g. E. cruciferarum), peas and bean (e.g. E. polygoni)·, Eutrypa lata (Eutypa canker or dieback, anamorph: Cytosporina lata, syn. Libertella blepharis ) on fruit trees, vines and ornamental woods; Exserohilum (syn. Helminthosporium ) spp. on corn (e.g. E. turcicumf, Fusarium (teleomorph: Gibberella ) spp. (wilt, root or stem rot) on various plants, such as hardlock, boll rot of cotton, F. graminearum or F. culmorum (root rot, scab or head blight) on cereals (e.g. wheat or barley), F. oxysporum on tomatoes, F. solani on soybeans and F. verticillioides on corn; Gaeumannomyces graminis (take-all) on cereals (e.g. wheat or barley) and corn; Gibberella spp. on cereals (e.g. G. zeae) and rice (e.g. G. fujikuroi: Bakanae disease); Glomerella cingulata on vines, pome fruits and other plants and G. gossypii on cotton; Grain staining complex on rice; Guignardia bidwellii (black rot) on vines, Guignardia citricarpa (balck spot) on citrus fruits; Gymnosporangium spp. on rosaceous plants and junipers, e.g. G. sabinae (rust) on pears; Helmintho sporium spp. (syn. Drechslera, teleomorph: Cochliobolu ) on corn, cereals and rice; Hemileia spp., e.g. H. vastatrix (coffee leaf rust) on coffee; Isariopsis clavispora (syn. Cladosporium vitis ) on vines; Kabatiella zeae (eyespot) on corn; Leptosphaeria maculans (blackleg) on oilseed crops; Leptosphaerulina spp. on peanut (e.g. L. crassiasca : pepperspot); Macrophomina phaseolina (syn. phaseoli) (root and stem rot) on soybeans and cotton; Microdochium (syn. Fusarium ) nivale (pink snow mold) on cereals (e.g. wheat or barley); Microsphaera diffusa (powdery mildew) on soybeans; Myeosphaerella citri (greasy spot) on citrus fruit, Monilinia spp., e.g. M. laxa, M. fructicola and M. fructigena (bloom and twig blight, brown rot) on stone fruits and other rosaceous plants; Myeosphaerella spp. on peas and beans, cereals, bananas, soft fruits and ground nuts, such as e.g. M. graminicola (anamorph: Septoria tritici, Septoria blotch ) on wheat or M. fijiensis (black Sigatoka disease) on bananas; Peronospora spp. (downy mildew) on cabbage (e.g. P. brassicae), rape (e.g. P. parasitica), onions (e.g. P. destructor), tobacco (P. tabacind) and soybeans (e.g. P. manshurica)·, Phyllosticta maydis (yellow leaf blight) on corn; Phakopsora pachyrhizi and P. meibomiae (soybean rust) on soybeans; Phialophora spp. e.g. on vines (e.g. P. tracheiphila and P. tetraspord) and soybeans (e.g. P. gregata: stem rot); Phoma lingam (root and stem rot) on rape and cabbage and P. betae (root rot, leaf spot and damping-off) on sugar beets, Phoma exigua (ascochyta blight) on peas and beans, phoma blight, boh rot on cotton, Phoma arachidicola (web blotch) on peanut; Phomopsis spp. on sunflowers, vines (e.g. P. viticola: can and leaf spot) and soybeans (e.g. stem rot: phaseoli, teleomorph: Diaporthe phaseolorum) Phykopsora spp. e.g. rust on cotton, Physoderma maydis (physoderma brown spot) on corn; Phytophthora spp. (wilt, root, leaf, fruit and stem root) on various plants, such as paprika and cucurbits (e.g. P. capsici), soybeans (e.g. P. megasperma, syn. P. sojae), potatoes and tomatoes (e.g. P. infestans : late blight), broad-leaved trees (e.g. P. ramorum: sudden oak death) and peas and beans (e.g. P. nicotianae : downy mildew); Plasmodiophora brassicae (club root) on cabbage, rape, radish and other plants; Plasmopara spp., e.g. P. viticola (downy mildew) on vines and P. halstedii on sunflowers; Podosphaera spp. (powdery mildew) on rosaceous plants, hop, pome and soft fruits, e.g. P. leucotricha on apples; Polymyxa spp., e.g. on cereals, such as barley and wheat (P. graminis ) and sugar beets (P. betae ) and thereby transmitted viral diseases; Pseudocercosporella herpotrichoides (eyespot, teleomorph: Tapesia yallundae ) on cereals, e.g. wheat or barley; Pseudoperonospora (downy mildew) on various plants, e.g. P. cubensis on cucurbits or P. humili on hop; Pseudopezicula tracheiphila (red fire disease or rotbrenner, anamorph: Phialophora ) on vines; Puccinia spp. (rusts) on various plants, e.g. P. triticina (brown or leaf rust), P. striiformis (stripe or yellow rust), P. hordei (dwarf rust), P. graminis (stem or black rust) or P. recondita (brown or leaf rust) on cereals, such as e.g. wheat, barley or rye (P. recondita), P. kuehnii (orange rust) on sugar cane and P. asparagi on asparagus, P. coronata (crown rust) and P. graminis (stem rust) on oats, P. arachidis (rust) on peanut; Pyrenophora (anamorph: Drechslerd) tritici-repentis (tan spot) on wheat, P. feres (net blotch) on barley, or P. avenae (leaf blotch) on oats; Pyricularia spp., e.g. P. oryzae (teleomorph: Magnaporthe grisea, rice blast) on rice and P. grisea on turf and cereals; Pythium spp. (damping-off) on turf, rice, corn, wheat, cotton, rape, sunflowers, soybeans, sugar beets, vegetables and various other plants (e.g. P. ultimum or P. aphanidermatum) Ramularia spp., e.g. R. collo-cygni ( Ramularia leaf spots, physiological leaf spots) on barley and mint, and R. beticola on sugar beets; Rhizoctonia spp. on cotton, rice, potatoes, turf, com, rape, potatoes, sugar beets, vegetables and various other plants, e.g. R. solani (root and stem rot) on soybeans, R. solani (sheath blight) on rice and peanut, or R. cerealis (Rhizoctonia spring blight) on wheat or barley; Rhizopus stolonifer (black mold, soft rot) on strawberries, carrots, cabbage, vines and tomatoes; Rhynchosporium secalis (scald) on barley, rye and triticale; Sarocladium oryzae and S. attenuatum (sheath rot) on rice; Sclerotinia spp. (stem rot or white mold) on vegetables and field crops, such as rape, sunflowers (e.g. S. sclerotiorum ) and soybeans (e.g. S. rolfsii or S. sclerotiorum ), S. minor (sclerotinia blight) on peanut, S. sclerotiorum (white mold) on potato; Sclerotium spp. on peanut (e.g. S. rolfsii), Septoria spp. on various plants, e.g. S. glycines (brown spot) on soybeans, S. tritici (Septoria blotch) on wheat and S. nodorum (syn. Stagonospora ) (Stagonospora blotch) on cereals, S. avenae (septoria blotch) on oats, S. linicola (pasmo) on flax seed; Uncinula (syn. Erysiphe ) necator (powdery mildew, anamorph: Oidium tuckeri ) on vines; Setospaeria spp. (leaf blight) on corn (e.g. S. turcicum, syn. Helminthosporium turcicum) and turf; Sphacelotheca spp. (smut) on corn, (e.g. S. reiliana: head smut), sorghum und sugarcane; Sphaerotheca fuliginea (powdery mildew) on cucurbits; Spongospora subterranea (powdery scab) on potatoes and thereby transmitted viral diseases; Stagonospora spp. on cereals, e.g. S. nodorum (Stagonospora blotch, teleomorph: Leptosphaeria (syn. Phaeosphaeria) nodorum) on wheat, septrotia leaf and glume blotch on rye; Stemphyllium spp. e.g. stemphyllium leaf spot on cotton, Synchytrium endobioticum on potatoes (potato wart disease); Taphrina spp., e.g. T. deformans (leaf curl disease) on peaches and T. pruni (plum pocket) on plums; Thielaviopsis spp. (black root rot) on tobacco, pome fruits, vegetables, soybeans and cotton, e.g. T. basicola (syn. Chalara elegans), Tilletia spp. (common bunt or stinking smut) on cereals, such as e.g. T. tritici (syn. T. caries, wheat bunt) and T. controversa (dwarf bunt) on wheat; Typhula incarnata (grey snow mold) on barley or wheat; Urocystis spp., e.g. U. occulta (stem smut) on rye; Uromyces spp. (rust) on vegetables, such as beans (e.g. U. appendiculatus, syn. U. phaseoli) and sugar beets (e.g. U. betae), Ustilago spp. (loose smut) on cereals (e.g. U. nuda and U. avaenae), corn (e.g. U. maydis: corn smut) and sugar cane; Venturia spp. (scab) on apples (e.g. V. inaequalis) and pears; and Verticillium spp. (wilt) on various plants, such as fruits and ornamentals, vines, soft fruits, vegetables and field crops, e.g. V. dahliae on strawberries, rape, potatoes and tomatoes.

In a preferred embodiment, the present invention provides a fungicidal composition comprising of tolfenpyrad and pyraclostrobin to control the undesired pathogenic microorganisms selected from the group comprising of, but not limited to, downy mildew, powdery mildew, black shank, black spot, melanose, post bloom fruit drop, anthracnose, alternaria brown spot, scab or greasy spot, leaf rust, black point, net blotch, scald, septoria leaf and glume blotch, spot blotch, stem rust, stripe or yellow rust, yellow leaf spot, eyespot, gray leaf spot, northern corn leaf spot, physoderma brown spot, rust, southern corn leaf blight, yellow leaf blight, leaf blast, or late blight. The combination or the composition of the present invention is also suitable for controlling the undesired pathogenic microorganisms occurring in plant parts, in the protection of materials (e.g. wood, paper, paint dispersions, fiber or fabrics) and in the protection of stored products. The term“protection of materials” is to be understood to denote the protection of technical and non-living materials, such as adhesives, glues, wood, paper and paperboard, textiles, leather, paint dispersions, plastics, cooling lubricants, fiber or fabrics, against the infestation and destruction by undesired pathological microorganisms, such as fungi and bacteria. As to the protection of wood and other materials, the particular attention is paid to the following undesired pathogenic microorganisms: Ascomycetes such as Ophiostoma spp., Ceratocystis spp., Aureobasidium pullulans, Sclerophoma spp., Chaetomium spp., Humicola spp., Petriella spp., Trichurus spp.; Basidiomycetes such as Coniophora spp., Coriolus spp., Gloeophyllum spp., Lentinus spp., Pleurotus spp., Poria spp., Serpula spp. and Tyromyces spp., Deuteromycetes such as Aspergillus spp., Cladosporium spp., Penicillium spp., Trichorma spp., Altemaria spp., Paecilomyces spp. and Zygomycetes such as Mucor spp., and in addition in the protection of stored products the following undesired pathogenic microorganisms are worthy of note: Candida spp. and Saccharomyces cerevisae.

The composition of the present invention also provides a nonagronomic (other than field crops) application such as application on horticultural crops (e.g., greenhouse, nursery or ornamental plants not grown in a field), residential, commercial and industrial structures, turf (e.g., sod farm, pasture, golf course, lawn, sports field, etc.).

In an embodiment, the present invention provides a method for controlling insect pests and mites with an effective amount of the composition of tolfenpyrad and pyraclostrobin.

Insect pests or mites is selected from the order of moths and butterflies ( Lepidoptera ), beetles ( Coleoptera ), flies, mosquitoes (Dipteral), thrips (Thysanoptera), termites ( Isoptera ), cockroaches (Blattaria - Blattoded), true bugs ( Hemiptera ), crickets, grasshoppers, locusts (_' Orthoptera ), arachnids ( Acarina ), fleas ( Siphonaptera ), silverfish, firebrat ( Thysanura ), millipedes ( Diplopoda ), earwigs ( Dermaptera ), lice ( Phthiraptera ), or plant parasitic nematodes.

In a further embodiment of the present invention defines the insect pests and mites from the orders of: lepidopterans ( Lepidoptera ), for example Agrotis ypsilon, Agrotis segetum (cutworm), Alabama argillacea, Anticarsia gemmatalis, Argyresthia conjugella, Autographa gamma, Bupalus piniarius, Cacoecia murinana, Capua reticulana, Cheimatobia brumata, Choristoneura fumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydia pomonella, Cydia caryana (hickory shuckworm), Dendrolimus pini, Diaphania nitidalis, Diatraea grandosella, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bouliana, Feltia subterranea, Galleria mellonella, Grapholitha funebrana, Grapholitha molesta,Heliothis armigera, Heliothis virescens (tobacco budworm), Heliothis zea, Hellula undalis, Hibemiadefoliaria, Hyphantria cunea, Hyponomeuta malinellus, Keiferia lycopersicella, Lambdina fiscellaria, Laphygma exigua, Leucoptera co feella, Leucoptera scitella, Lithocolletis blancardella, Lobesia botrana, Loxostege sticticalis, Lymantria dispar, Lymantria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae, Orgyia pseudotsugata, Ostrinia nubilalis (european corn borer), Panolis flammea, Pectinophora gossypiella (pink bollworm), Peridroma saucia, Phalera bucephala, Phthorimaea operculella, Phyllocnistis citrella, Pieris brassicae, Pieris rapae (imported cabbageworm), Plathypena scabra, Plutella xylostella, Pseudoplusia includens, Rhyacionia frustrana, Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera frugiperda (fall armyworm), Spodoptera littoralis, Spodoptera litura, Thaumatopoea pityocampa, Tortrix viridana, Trichoplusia ni, Zeiraphera canadensis, Giant swallowtail (orangedog), Paralobesia viteana (grape berry moth), Desmia funeralis (grape leaffolder), Helicoverpa zea (corn earworm), Helicoverpa armigeral (cotton bollworm), Agrotis segetum, Agrotis ipsilon, Agrotis exclamationis, Manduca quinquemaculata (tomato hornworm), Lithophane antennata (green fruitworm), Lithophane unimoda, Orthosia hibisci, Anarsia lineatella (peach twig borer), Acrobasis nuxvorella (pecan nut casebearer), Amyelois transitella (navel orangeworm), Marmara gulosa (Citrus peelminer)and Harrisina Americana (Grapeleaf skeletonizer), beetles ( Coleoptera ), for example Agrilus sinuatus, Agriotes lineatus, Agriotes obscurus, Amphimallus solstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum, Aphthona euphoridae, Athous haemorrhoidalis, Atomaria linearis, Blastophagus piniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum, Bruchus lends, Byctiscus betulae, Cassida nebulosa, Cerotoma trifurcata, Cetonia aurata, Ceuthorrhynchus assimilis, Ceuthorrhynchus napi, Chaetocnema tibialis, Conoderus vespertinus, Crioceris asparagi, Ctenicera ssp., Curculio caryae (pecan weevil), Diabrotica longicornis, Diabrotica semipunctata, Diabrotica 12-punctata, Diabrotica speciosa, Diabrotica virgifera, Epilachna varivestis, Epitrix hirtipennis, Eutinobothrus brasiliensis, Hylobius abietis, Hypera brunneipennis, Hypera postica, Ips typographus, Lema bilineata, Lema melanopus, Leptinotarsa decemlineata (Colorado potato beetle), Limonius califomicus, Lissorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melolontha hippocastani, Melolontha melolontha, Oulema oryzae, Ortiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllobius pyri, Phyllotreta chrysocephala, Phyllophaga sp., Phyllopertha horticola, Phyllotreta nemorum, Phyllotreta striolata, Popillia japonica (Japanese beetle), Sitona lineatus, Sitophilus granaria, Diaprepes abbreviatus, and Conotrachelus nenuphar (plum curculio), flies, mosquitoes ( Diptera ), e.g. Aedes aegypti, Aedes albopictus, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Anopheles crucians, Anopheles albimanus, Anopheles gambiae, Anopheles freebomi, Anopheles leucosphyrus, Anopheles minimus, Anopheles quadrimaculatus, Calliphora vicina, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Chrysops discalis, Chrysops silacea, Chrysops atlanticus, Cochliomyia hominivorax, Contarinia sorghicola Cordylobia anthropophaga, Culicoides furens, Culex pipiens, Culex nigripalpus, Culex quinquefasciatus, Culex tarsalis, Culiseta inomata, Culiseta melanura, Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Delia antique, Delia coarctata, Delia platura, Delia radicum, Dermatobia hominis, Drosophila suz.ukii (spotted wing drosophila), Fannia canicularis, Geomyza Tripunctata, Gasterophilus intestinalis, Glossina morsitans, Glossina palpalis, Glossina fuscipes, Glossina tachinoides, Haematobia irritans, Haplodiplosis equestris, Hippelates spp., Hylemyia platura, Hypoderma lineata, Leptoconops torrens, Liriomyza sativae, Liriomyza trifolii, Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mansonia titillanus, Mayetiola destructor, Musca domestica, Muscina stabulans, Oestrus ovis, Opomyza florum, Oscinella frit, Pegomya hysocyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Phlebotomus argentipes, Psorophora columbiae, Psila rosae, Psorophora discolor, Prosimulium mixtum, Rhagoletis cerasi, Rhagoletis pomonellal (apple maggot), Sarcophaga haemorrhoidalis, Sarcophaga sp., Simulium vittatum, Stomoxys calcitrans, Tabanus bovinus, Tabanus atratus, Tabanus lineola, Tabanus similis, Tipula oleracea, Tipula paludosa, and Rhagoletis cerasi (cherry fruit fly), thrips ( Thysanoptera ), e.g. Dichromothrips corbetti, Dichromothrips ssp., Frankliniella fusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri (Citrus thrips), Thrips oryzae, Thrips palmi, Thrips tabaci, and Drepanothrips reuteri (grape thrips) termites ( Isoptera ), e.g. Calotermes flavicollis, Leucotermes flavipes, Heterotermes aureus, Reticulitermes flavipes, Reticulitermes virginicus, Reticulitermes lucifugus, Termes natalensis, and Coptotermes formosanus, cockroaches (Blattaria - Blattodea), e.g. Blattella germanica, Blattella asahinae, Penplaneta americana, Periplaneta japonica, Periplaneta brunnea, Periplaneta fuligginosa, Periplaneta australasiae, and Blatta orientalis,

true bugs ( Hemiptera ), e.g. Diaphorina citri, Acrostemum hilare, Blissus leucopterus, Cyrtopeltis notatus, Dysdercus cingulatus, Dysdercus intermedius, Eurygaster integriceps, Euschistus impictiventris, Leptoglossus phyllopus, Lygus lineolaris, Lygus pratensis, Nezara viridula, Piesma quadrata, Solubea insularis , Thyanta perditor, Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Aphis fab ae, Aphis forbesi, Aphis pomi, Aphis gos sypii, Aphis grossulariae, Aphis schneideri, Aphis spiraecola, Aphis sambuci, Acyrthosiphon pisum, Aulacorthum solani, Bemisia argentifolii, Brachycaudus cardui, Brachycaudus helichrysi, Brachycaudus persicae, Brachycaudus prunicola, Brevicoryne brassicae, Capitophorus homi, Cerosipha gossypii, Chaetosiphon fragaefolii, Cryptomyzus ribis, Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola, Dysaulacorthum pseudosolani, Dysaphis plantaginea, Dysaphis pyri, Empoasca fabae, Hyalopterus pruni, Hyperomyzus lactucae, Macrosiphum avenae, Macrosiphum euphorbiae, Macrosiphon rosae, Megoura viciae, Melanaphis pyrarius, Metopolophium dirhodum, Myzus persicae, Myzus ascalonicus, Myzus cerasi, Myzus varians, Nasonovia ribis-nigri, Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mail, Psylla piri, Rhopalomyzus ascalonicus, Rhopalosiphum maidis, Rhopalosiphum padi, Rhopalosiphum insertum, Sappaphis mala, Sappaphis mall, Schizaphis graminum, Schizoneura lanuginosa, Sitobion avenae, Trialeurodes vaporariorum,Toxoptera aurantiiaud, Viteus vitifolii, Cimex lectularius, Cimex hemipterus, Reduvius senilis, Triatoma spp., Cicadella viridis (green leafhoppers), Bactericera cockerelli (potato psyllid), Arilus critatus, Planococcus citri (citrus mealybug), Pseudococcus maritimus (grape mealybug), P seudatomoscelis seriatus (cotton fleahopper), Proxys punctulatus (black stink bug), Halyomorpha halys, Citri col a scale ( Coccus pseudomagnoliarum), Barnacle scale ( Ceroplastes cirripediformis), and Brown soft scale ( Coccus hesperidum ), ants, bees, wasps, sawflies ( Hymenoptera ), e.g. Athalia rosae, Atta cephalotes, Atta capiguara, Atta cephalotes, Atta laevigata, Atta robusta, Atta sexdens, Atta texana, Crematogasterspp., Hoplocampa minuta, Hoplocampa testudinea, Monomorium pharaonis, Solenopsis geminata, Solenopsis invicta, Solenopsis richteri, Solenopsis xyloni, Pogonomyrmex barbatus, Pogonomyrmex californicus, Pheidole megacephala, Dasymutilla occidentalis, Bombus spp. Vespula squamosa, Paravespula vulgaris, Paravespula pennsylvanica, Paravespula germanica, Dolichovespula maculata, Vespa crabro, Polistes rubiginosa, Camponotus floridanus, and Linepithema humile, crickets, grasshoppers, locusts ( Orthoptera ), e.g. Acheta domestica, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplus bivittatus, Melanoplus femurrubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Schistocerca americana, Schistocerca gregaria, Dociostaurus maroccanus, Tachycines asynamorus, Oedaleus senegalensis, Zonozerus variegatus, Hieroglyphus daganensis, Kraussaria angulifera, Calliptamus italicus, Chortoicetes terminifera, Scudderia spp. (katydid) and Locustana pardalina,

Arachnoidea, such as arachnids ( Acarina ), e.g. of the families Argasidae, Ixodidae and Sarcoptidae, such as Amblyomma americanum, Amblyomma variegatum, Ambryomma maculatum, Argas persicus, Boophilus annulatus, Boophilus decoloratus, Boophilus microplus, Dermacentor silvarum, Dermacentor andersoni, Dermacentor variabilis, Hyalomma truncatum, Ixodes ricinus, Ixodes rubicundus, Ixodes scapularis, Ixodes holocyclus, Ixodes pacificus, Omithodorus moubata, Omithodorus hermsi, Omithodorus turicata, Omithonyssus bacoti, Otobius megnini, Dermanyssus gallinae, Psoroptes ovis, Rhipicephalus sanguineus, Rhipicephalus appendiculatus, Rhipicephalus evertsi, Sarcoptes scabiei, and Eriophyidae spp. such as Aculus schlechtendali, Phyllocoptrata oleivora (citrus rust mite), Aceria sheldoni (citrus bud mite) and Eriophyes sheldoni; Tarsonemidae spp. such as Phytonemus pallidus and Polyphagotarsonemus latus; Tenuipalpidae spp. such as Brevipalpus phoenicis; Tetranychidae spp. such as Tetranychus cinnabarinus, Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius and Tetranychus urticae, Panonychus ulmi, Panonychus citri (citrus red mite), and Oligonychus pratensis; Araneida, e.g. Latrodectus mactans, and Loxosceles reclusa, fleas ( Siphonaptera ), e.g. Ctenocephalides felis, Ctenocephalides canis, Xenopsylla cheopis, Pulex irritans, Tunga penetrans, and Nosopsyllus fasciatus, silverfish, firebrat ( Thysanura ), e.g. Lepisma saccharina and Thermobia domestica,

centipedes ( Chilopoda ), e.g. Scutigera coleoptrata,

millipedes ( Diplopoda ), e.g. Narceus spp.,

earwigs ( Dermaptera ), e.g .forficula auricularia,

lice ( Phthiraptera ), e.g. Pediculus humanus capitis, Pediculus humanus corporis, Pthirus pubis, Haematopinus eurystemus, Haematopinus suis, Linognathus vituli, Bovicola bovis, Menopon gallinae, Menacanthus stramineus and Solenopotes capillatus, plant parasitic nematodes such as root-knot nematodes, Meloidogyne arenaria, Meloidogyne chitwoodi, Meloidogyne exigua, Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica and other Meloidogyne species; cyst nematodes, Globodera rostochiensis, Globodera pallida, Globodera tabacum and other Globodera species, Heterodera avenae, Heterodera glycines, Heterodera schachtii, Heterodera trifolii, and other Heterodera species; seed gall nematodes, Anguina funesta, Anguina tritici and other Anguina species; stem and foliar nematodes, Aphelenchoides besseyi, Aphelenchoides fragariae, Aphelenchoides ritzemabosi and other Aphelenchoides species; sting nematodes, Belonolaimus longicaudatus and other Belonolaimus species; pine nematodes, Bursaphelenchus xylophilus and other Bursaphelenchus species; ring nematodes, Criconema species, Criconemella species, Criconemoides species, and Mesocriconema species; stem and bulb nematodes, Ditylenchus destructor, Ditylenchus dipsaci, Ditylenchus myceliophagus and other Ditylenchus species; awl nematodes, Dolichodorus species; spiral nematodes, Helicotylenchus dihystera, Helicotylenchus multicinctus and other Helicotylenchus species, Rotylenchus robustus and other Rotylenchus species; sheath nematodes, Hemicycliophora species and Hemicriconemoides species; Hirshmanniella species; lance nematodes, Hoplolaimus columbus, Hoplolaimus galeatus and other Hoplolaimus species; false root-knot nematodes, Nacobbus aberrans and other Nacobbus species; needle nematodes, Longidorus elongates and other Longidorus species; pin nematodes, Paratylenchus species; lesion nematodes, Pratylenchus brachyurus, Pratylenchus coffeae, Pratylenchus curvitatus, Pratylenchus goodeyi, Pratylencus neglectus, Pratylenchus penetrans, Pratylenchus scribneri, Pratylenchus vulnus, Pratylenchus zeae and other Pratylenchus species; Radinaphelenchus cocophilus and other Radinaphelenchus species; burrowing nematodes, Radopholus similis and other Radopholus species; reniform nematodes, Rotylenchulus reniformis and other Rotylenchulus species; Scutellonema species; stubby root nematodes, Trichodorus primitivus and other Trichodorus species; Paratrichodorus minor and other Paratrichodorus species; stunt nematodes, Tylenchorhynchus claytoni, Tylenchorhynchus dubius and other Tylenchorhynchus species and Merlinius species; citrus nematodes, Tylenchulus semipenetrans and other Tylenchulus species; dagger nematodes, Xiphinema americanum, Xiphinema index, Xiphinema diver sicaudatum and other Xiphinema species; and other plant parasitic nematode species.

In a preferred embodiment, the present invention provides an insecticidal combination/composition comprising of tolfenpyrad and pyraclostrobin to control the insect pests and mites from the order of Lepidoptera, Coleoptera, Diptera, Hemiptera, Orthoptera, Acarina and Thysanoptera insects.

The composition of the present invention used to control a wide variety of undesired pathogenic microorganisms, insect pests and mites, is advantageous, for several purposes, e.g.:

• useful for addressing a wider range of pest and diseases e.g. insecticidal, fungicidal and acaricidal activity;

• offering a single application as a uniform composition in place of separate application of fungicides and insecticides;

• offering crop health improvement in comparison to separate applications of fungicides and insecticides;

• longer residual control after application of the composition.

In another embodiment, the present invention provides a combination/composition that shows enhanced action against undesired pathogenic microorganisms, insect pests and mites, in comparison to the control rates that are possible with the individual compounds and/or suitable for improving the health of plants when applied to plants, parts of plants, plant propagation materials, or at their locus of their growth. In yet another embodiment, the combination or the composition of the present invention is particularly important for controlling a multitude of undesired pathogenic microorganisms, insect pests and mites, on various cultivated plants or plant parts, such as cereals, e.g. wheat, rye, barley, triticale, oats or rice; beet, e.g. sugar beet or fodder beet; fruits, such as pomes, stone fruits or soft fruits, e.g. apples, pears, plums, peaches, almonds, cherries, strawberries, raspberries, nectarine, prune, blackberries or gooseberries; leguminous plants, such as lentils, peas, alfalfa or soybeans; oil plants, such as rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palms, ground nuts or soybeans; cucurbits, such as squashes, cucumber or melons; fiber plants, such as cotton, flax, hemp or jute; citrus fruit, such as oranges, lemons, grapefruits or mandarins; vegetables, such as spinach, lettuce, asparagus, cabbages, carrots, onions, tomatoes, potatoes, cucurbits or paprika; lauraceous plants, such as avocados, cinnamon or camphor; energy and raw material plants, such as corn, soybean, rape, sugar cane or oil palm; corn; tobacco; nuts; coffee; tea; bananas; vines (table grapes and grape juice grape vines); hop; turf; sweet leaf (also called Stevia); natural rubber plants or ornamental and forestry plants, such as flowers, shrubs, broad-leaved trees or evergreens, e.g. conifers; and on the plant propagation material, such as seeds, and the crop material of these plants.

In a preferred embodiment, the combination or composition of the present invention is particularly important for controlling a multitude of undesired pathogenic microorganisms, insect pests and mites, in the cucumber crop.

The rate of application amount varies depending on, for example, the blending ratio of an active ingredient, a metrological condition, a dosage form, an application time, an application method, an application place, a pest to be controlled, and a target crop, in ordinary cases.

In the method of combating harmful fungi depending on the type of compound and the desired effect, the application rates of the mixture according to the invention are , preferably from 5 to 1000 g/ha, most preferably from 10 to 750 g/ha, in particular from 20 to 500 g/ha.

In the method of combating pests (insects, acarids or nematodes) depending on the type of compound and the desired effect, the application rates of the mixture according to the invention are from , preferably from 20 to 1000 g/ha, more preferably from 10 to 750 g/ha, in particular from 20 to 500 g/ha.

In an embodiment, the present invention provides a method for improving crop health (phyto- tonic effect), comprising treating a plant with an effective amount of composition of tolfenpyrad and pyraclostrobin.

The present invention is further illustrated by the following examples. These examples describe possible preferred embodiments for illustrative purposes only, but they do not limit the scope of the invention.

Example 1: Emulsifiable concentrate (EC)

Preparation Method: Polyoxyethylene alkyl ether 3.0 parts, polyoxiethylene tristyrylppenol ether 2.0 parts and calcium alkylbenzene sulfonate were put into a mixture of N-methyl-2- pyrrolidone 5.0 parts and xylene 60.1 parts under mixing with an overhead stirrer and well mixed. Into this mixture, tolfenpyrad technical 15.5 parts and then pyraclostrobin technical 10.4 parts were added by portion wise. This mixture was well mixed till all materials were completely solved.

Example 2: Oil-in water emulsion (EW)

Preparation Method: Tolfenpyrad technical 7.80 parts and pyraclostrobin 5.20 parts were completely solved into xylene 15.00 parts. Polyoxyethylene castor oil ether 4.00 parts, polyoxyethylene polyoxypropylene block copolymer 7.00 parts, poly dimethyl siloxane emulsion 0.10 parts, l,2-benzisothiazolin-3-one 0.05 parts, polyethylene glycol 5.00 parts and water 35.85 parts were well mixed in a collodal mill. Into this mixture, the xylene solution of tolfenpyrad and pyraclostrobin was put portion wise and emulsified till the median diameter of oil droplet becomes below 2 pm. Into the prepared emulstion mixture, xanthan gum 1% aqueous solution 20.00 parts was added and mixed uniformly.

Example 3: Wettable Powder (WP)

Preparation Method: Kaolin 59.1 parts and precipitated silica 6.0% were well mixed in a high shear mixer. After mixing well, tolfenpyrad technical 15.5 parts, pyroxastrobin technical 10.4 parts, sodium alkyl sulfate 3.0 parts, sodium lignin sulfonate 2.0 parts and sodium naphthalene sulfonate formaldehyde condensate 4.0 parts were added and mixed well in a high shear mixer. The mixture was milled by an air jet mill under operaton condition to get the median diameter below 10 pm.

Example 4: Water dispersible granule (WG)

Preparation Method: Ammonium sulfate 16.7 parts, kaolin 16.7 parts and fumed silica 2.0% were well mixed in a high shear mixer. After mixing well, tolfenpyrad technical 31.0 parts, pyroxastrobin technical 20.6 parts, sodium naphthalene sulfonate formaldehyde condensate 3.0 parts, sodium lignin sulfate 8.0 parts and sodium alkyl sulfonate 2.0 parts and were added, and mixed well in a high shear mixer. The mixture was milled by an air jet mill under operaton condition to get the median diameter below 10 pm. The resulting mixture was kneaded with water, extruded through a screen (0.8 mm diameter opening) and dried. Example 5: Suspension Concentrate (SC)

Preparation Method: Polyoxyethylene alkyl ether 3.00 parts, polymethacrylate -poly oxy ethylene graft copolymer 4.00 parts, sodium naphthalene sulfonate formaldehyde condensate 1.00 parts, l,2-benzisothiazolin-3-one 0.05 parts and polysiloxane emulsion 0.30 parts were mixed into a solution of distilled water 44.75 parts and polyethylene glycol 6.00 parts. Into this mixture, tolfenpyrad technical 15.50 parts and pyraclostrobin technical 10.40 were added and pre-milled in a colloidal mill till the median diameter of tolfenpyrad technical and pymetrozine technical become below 100 micrometers. The pre-milled mixture was milled in a bead mill till the median diameter of the technicals become below 5 pm. After milling, xanthan gum aqueous 1% solution 15.00 parts is added into the milled solution and mixed uniformly. Following the test results illustrate the present invention and are not intended to limit the present invention. Example: Biological effect of Combination of Tolfenpyrad and Pyraclostrobin:

Experiments were carried out to study the biological efficacy in ter s of disease, pest control, crop vigour, and yield with the combinations of the present invention. Bio-efficacy assessments were done for control of Downey mildew, Powdery mildew, Jassid and thrips in cucumber and its indirect influence on cucumber vigour and yield.

Trials were conducted in open field to test the efficacy of the combination of tolfenpyrad and pyraclostrobin for controlling downy mildew, powdery mildew, thrips and jassid in cucumber at different test doses. The test compounds were applied 30 days after sowing at the given application rates with the help of back pack sprayers fitted with a hollow cone nozzle. The water volume used for spraying was 5001ts/ha, the size of each plot was 50 sq. mt and each treatment was replicated 3 times. Disease and pest severity was recorded one day before application and 10 days post application. Crop vigour was recorded at 30 days after application. The cucumber was harvested at a weekly interval based on the maturity index of green cucumber. Six picking yield was recorded. At application time the cucumber crop (Cucumber) indicated 8% downy mildew and 10% powdery mildew severity, while the mean pre -count of jassids was 3/leaf and thrips was 5/leaf. At data recording time, the disease severity of downy mildew was 25% and of powdery mildew was 35% in the untreated plots while the jassid population was 8/leaf and thrips population was 15/leaf at data recording. The composition comprising the compound of component (1) and the component (2) shows a synergistic effect. According to the present invention, a synergistic effect of the combination is always present when the pesticidal activity of the active compound combinations exceeds the total of the activities of the single combining partners when applied individually. The expected activity for a given combination of two active compounds (binary mixture) can be calculated by using Colby’s formula (COLBY, S.R. “Calculating synergistic and antagonistic responses of herbicide combination”, Weeds, Vol. 15, pages 20-22; 1967).

Colby's formula:

The expected activity for a given combination of two active compounds (binary composition) can be calculated as follows:

XY

E ~ X + Y

loo

In which E represents the expected percentage of inhibition of the disease for the combination of two pesticides at defined doses (for example equal to x and y respectively), x is the percentage of inhibition observed for the disease by the compound (1) at a given dose (equal to x), y is the percentage of inhibition observed for the disease by the compound (2) at a defined dose (equal to y). When the percentage of inhibition observed for the combination is greater than E, there is a synergistic effect.

Here the efficacy is determined in %. 0% means an efficacy which corresponds to that of the control; whereas 100 % means that no infection is observed.

If an actual combination exceeds the calculated value, the action of the combination is super additive i.e., a synergistic effect is present, in this case, the actually observed efficacy must exceed the value calculated using the above formula for expected efficacy (E). In the case of purely complementary addition of activities (expected activity), said difference (O-E) is zero. A negative value of the difference (O-E) signals a loss of activity compared to the expected efficacy. However, besides the actual synergistic action with respect to fungicidal activity, the composition according to the invention can also have further surprising advantageous properties. Examples of such advantageous properties that may be mentioned are more advantageous degradability; improved toxicological and ecotoxicological behaviours; or improved characteristics of the useful plants including, emergence, crop yields, more developed root system, tillering increases, increase in plant height, bigger leaf blades, stronger tillers, greener leaf colours, early flowering, early maturity, increased shoot growth, increased plant vigour and early germination.

The agrochemical composition of the present invention also exhibits vigourous growth in crop. Vigour, here refers to early leaf area development and growth rate of the crop, has often been associated with improved competitive ability. Rapid canopy closure allows crops to quickly shade the ground and competing plants. Vigourous early growth may also promote greater root growth and improve water-use efficiency (Siddique et al., 1990; Richards et al., 2007; Richards, 2008), which may contribute to higher yields in water and nutrient-limited environments overall a potent strengthening effect in plants is observed. Accordingly, they can be used for mobilizing the defenses of the plant against attack by undesirable microorganisms. Increased plant vigour, comprising plant health/plant quality and seed vigour, reduced stand failure, improved appearance, increased recovery after periods of stress, improved pigmentation (e.g. chlorophyll content, stay-green effects, etc.) and improved photosynthetic efficiency.

Table 1 : Vigour index followed

Under optimal conditions, more fruit may initially develop from the axil of 4 per leaf than can later be supported to full size, so fruit may need thinning. Plants allowed to bear too much fruit become exhausted, abort fruit, and fluctuate widely in productivity over time. Excessive plant vigor is indicated by rapid growth, thick and brittle stems, large leaves, long tendrils, deep green foliage, the profusion of fruit, and large, deep yellow flowers. On the other hand, cucumbers are very sensitive to unfavorable conditions, and the slightest stress affects their growth and productivity.

Effects of the combinations on disease control, pest control, vigour and yield of cucumber are given in the following tables. Table 2: Activity of the combination on Downey mildew of Cucumber

It was thus concluded that the combinations of the present invention were surprisingly synergistically efficacious for the control of downy mildew. Table 3: Activity of the combination on Powdery mildew of Cucumber

It was thus concluded that the combinations of the present invention were surprisingly synergistically active for the control of Powdery mildew.

5

Table 4: Activity of the combination on Jassid of Cucumber

It was thus concluded that the combinations of the present invention surprisingly indicated jassids control synergies.

1 0 Table 5: Activity of the combination on Thrips of Cucumber

Synergies in terms of thrips control with the said combinations are clearly reflected in the data.

Table 6: Activity of the combination on crop vigour

It was thus concluded that the cucumber crop treated with the test combinations according to the present invention surprisingly indicated synergies in terms of vigour which could be caused by the effective disease control, pest control and the activation of some beneficial physiological pathways. Test combination of Tolfenpyrad + Pyraclostrobin @ 150 + 100 & 80 g a.i./ha indicated the highest synergies in terms of crop vigour. Delayed onset of senescence in the combination plots was one of the key observations at maturity which led to an extended crop cycle of 10 days.

5

Table 7: Activity of the combination on yield of Cucumber

Synergies seen in terms of increased yield can be attributed to better pest and disease control and delayed senescence.

1 0

Thus, from the foregoing description, it will be apparent to one of the person skilled in the art that many changes and modifications can be made thereto without departing from the spirit or scope of the invention as set forth in the description. Accordingly, it is not intended that the scope of the foregoing description be limited to the description set forth above, but rather that

15 such description be construed as encompassing such features that reside in the present invention, including all the features and embodiments that would be treated as equivalents thereof by those skilled in the relevant art.

Claims

Claims:

1. A composition comprising of

a) an effective amount of tolfenpyrad or salt(s) thereof,

b) an effective amount of pyraclostrobin or salt(s) thereof,

d) agriculturally acceptable additives.

2. A synergistic composition comprising of

a) an effective amount of tolfenpyrad or salt(s) thereof,

b) an effective amount of pyraclostrobin or salt(s) thereof,

d) agriculturally acceptable additives.

3. The composition as claimed in claim 1, wherein said composition comprises of weight percentage of tolfenpyrad is about 4% to 80%, preferably about 10% to 60%, the weight percentage of pyraclostrobin is about 80% to 4%, preferably about 60% to 10% and the weight percentage of additives is about 5% to 95%, preferably about 20% to 90%.

4. The composition as claimed in claim 1 , wherein the tolfenpyrad and pyraclostrobin in a ratio 50:1 to 1:50, preferably 20:1 to 1:20 or 10:1 to 1 :10, more preferably 3:2 to 2:3.

5. The composition as claimed in claim 1, wherein said composition is formulated as a wettable powder (WP), a water dispersible granule (WDG), a water dispersible powder, a water dispersible tablet (WT), a suspension concentrate (SC), an ultra-low volume (ULV) liquid, an ultralow volume (ULV) suspension (SU), a water soluble granule (SG), an emulsifiable granule (EG), an emulsifiable powder (EP), a dispersible concentrate (DC), an oil-in water emulsion (EW), an emulsifiable concentrate (EC), a micro-emulsion (ME), an oil dispersion (OD), a capsule suspension (CS), a du stable powder (DP) or an aerosol.

6. The composition as claimed in claim 1, wherein said composition further comprises of agriculturally acceptable formulation additives is selected from the group comprising of surfactant(s), liquid carrier(s), solid carrier(s), binder(s), disintegrating agent(s), pH adjuster(s), thickener(s), preservative(s), antifreezing agent(s), defoamer(s), coloring agent(s), or a combination thereof.

7. The composition as claimed in claim 6, wherein suitable surfactant(s) is selected from the group comprising of sorbitan monolaurate, polyoxyethylene sorbitan monolaurate; alkyl polyglucoside (decyl glucoside), polyoxyethylene alkyl ethers (polyoxyethylene lauryl ether, or polyoxyethylene coconut fatty alcohol ether), polyoxyethylene alkynyl ether (polyoxyethylene 2,4,7,9-tetramethyl-5-decyn-4,7-diol ether), polyoxyethylene aryl ethers (polyoxyethylene nonylphenyl ether or polyoxyethylene tristyrylphenyl ether), polyoxyethylene vegetable oil ethers (polyoxyethylene castor oil or polyoxyethylene hydrogenated castor oil), vegetable oil ethoxylate, alcohol C12-C15 ethoxy late; polyoxyethylene fatty acid esters (polyoxyethylene monolaurate, polyoxyethylene distearate or polyoxyethylene resin acid ester); polyoxyethylene polyoxypropylene (EO-PO) block co-polymers (Pluronic^®), polyoxyethylene polyoxypropylene alkyl ether (polyoxyethylene polyoxypropylene lauryl ether), polyoxyethylene polyoxypropylene aryl ether (polyoxyethylene polyoxypropylene styrylphenyl ether), polyoxyethylene alkyl amines (polyoxyethylene stearyl amine), polyoxyethylene fatty acid amide (lauric acid diethanolamid), fluorinated surfactant, alkyl sulfates (sodium lauryl sulfate), sodium alkylbenzene sulfonate, calcium alkylbenzene sulphonate, polyoxyethylene alkyl ether sulfates (sodium polyoxyethylene lauryl ether sulfate), polyoxyethylene aryl ether sulfates (sodium polyoxyethylene nonylphenyl ether sulfate or ammonium polyoxyethylene tristyrylphenyl ether sulfate), aryl sulfonate (calcium dodecyl benzene sulfonate, sodium naphthalene sulfonate or sodium naphthalene sulfonate formaldehyde condensate), poly aryl phenyl ether sulphate ammonium salt,‘alpha’ -olefin sulfonate, alkyl sulfosuccinate (sodium dioctyl sulfosuccinate), sodium lignosulfonate, polycarboxylic acid sodium salt, N-methyl fatty acid sarcosinate, polyoxyethylene alkyl ether phosphate, polyoxyethylene aryl ether phosphates (polyoxyethylene phenyl ether phosphate), polyoxyethylene alkyl phenyl ether phosphate, graft co polymers (polymethyl methacrylate-polyethylene glycol graft copolymer), or a combination thereof.

8. The composition as claimed in claim 6, wherein the suitable liquid carrier(s) is selected from the group comprising of water, alcohols (ethanol, propanol, butanol, n- octanol, isopropanol ethylene glycol, diethylene glycol, propylene glycol, polyethylene glycol, benzyl alcohol, glycerin), polyol ethers (ethylene glycol monopropyl ether, diethylene glycol monomethyl ether, dipropylene glycol dimethyl ether), ketones (acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone; ethers such as dipropyl ether, dioxane, tetrahydrofuran), aliphatic hydrocarbons (normal paraffin, isoparaffin, kerosene, mineral oil), aromatic hydrocarbons (xylene, toluene, naphthene, solvent naphtha, solvent C9, solvent C10, solvent C12, solvesso 100, solvesso 150, solvesso 200), chlorinated aliphatic or aromatics hydrocarbons (chlorobenzene, chloroethylene, methylene chloride); esters (ethyl acetate, diisopropyl phthalate, dimethyl adipate, methyl oleate, methyl tallowate), lactones (gamma- butyrolactone, gamma- valerolactone, epsilon-caprolactone), amides

(dimethylformamide, N-methylpyrrolidone, N-octylpyrolidone, N,N- dimethyldecanamide), nitriles (acetonitrile); organosulfur compound (dimethyl sulfoxide), vegetable oils (soybean oil, rapeseed oil, cotton seed oil) or a combination thereof.

9. The composition as claimed in claim 6, wherein suitable solid carrier(s) is selected from the group comprising of natural minerals (quartz, talc, kaolinite, pyrophyllite, montmorillonite, attapulgite, bentonite, kieselguhr, chalk, zeolite, calcite, sericite, acid clay, diatomaceous earth, Fuller’s earth, or pumice), synthetic minerals (precipitated silica, fumed silica and calcium carbonate), inorganic salts (calcium carbonate, ammonium sulfate, sodium sulfate, potassium chloride), organic materials (urea, lactose, starch, lignin, cellulose, cottonseeds hulls, wheat flour, soyabean flour, wood flour, walnut shell flour, plant powders), plastic carrier polyethylene, polypropylene or polyvinylidene chloride or a combination thereof.

10. The composition as claimed in claim 6, wherein suitable binder(s) is selected from the group comprising of polyvinyl alcohol, dextrin, denatured dextrin, soluble starch, guar gum, sucrose, polyvinylpyrrolidone, gum arabic, polyvinyl acetate, polysodium acrylate, carboxymethyl cellulose or its salt, carboxymethylcellulose dextrin, bentonite, polyethylene glycol having an average molecular weight of 6,000 to 20,000, polyethylene oxide having average molecular weight of 100,000 to 5,000,000, natural phosphatide (cephalinic acid or lecithin) or a combination thereof.

11. The composition as claimed in claim 6, wherein suitable disintegrating agent(s) is selected from the group comprising of sodium tripolyphosphate, stearic acid metal salt, cellulose powder, dextrin, methacrylate copolymer, polyvinylpyrrolidone, polyaminocarboxylic acid chelate compound, styrene sulfonate/isobutylene/maleic anhydride copolymer, starch/polyacrylonitrile graft copolymer, sodium hexametaphosphate, carboxymethyl cellulose, sodium polycarbonate, bentonite or a combination thereof.

12. The composition as claimed in claim 6, wherein suitable pH adjuster(s) is selected from the group comprising of sodium or potassium carbonate, sodium or potassium hydrogen carbonate, sodium or potassium dihydrogenphosphate, disodium or dipotassium hydrogenphosphate, citric acid, malic acid and triethanolamine, or a combination thereof.

13. The composition as claimed in claim 6, wherein suitable thickener(s) is selected from the group comprising of xanthan gum, welan gum, guar gum, polyvinyl alcohol, carboxylmethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic polymer, starch derivative or polysaccharide, silica, bentonite, or white carbon or a combination thereof.

14. The composition as claimed in claim 6, wherein suitable preservative(s) is selected from the group comprising of 4-hydroxybenzoic acid esters, 2-methyl-4-isothiazolin- 3-one, 5-chloro-2-methyl-4-isothiazolin-3-one and l,2-benzisothiazolin-3-one, or a combination thereof.

15. The composition as claimed in claim 6, wherein suitable anti-freezing agent(s) is selected from the group comprising of glycerin, ethylene glycol, polyethylene glycol, propylene glycol, diethylene glycol, dipropylene glycol and urea, or a combination thereof.

16. The composition as claimed in claim 6, wherein suitable defoamer(s) is selected from the group comprising of silicone compounds and organic fluorine compounds, or a combination thereof.

17. The composition as claimed in claim 6, wherein suitable coloring agent(s) is selected from the group comprising of organic dyestuffs (azo dye, phthalocyanine dye or alizarin dye) and inorganic pigments (iron oxide), or a combination thereof.

18. A method for controlling pest(s), wherein the pest, their habitat, breeding grounds, their locus, or the plants to be protected against pest attack, the soil or plant propagation material are treated with an effective amount of the composition of claim 1.

19. A method for controlling phytopathogenic harmful fungi, comprising treating a fungus, a habitat of the fungus, a seed, soil, or a plant to be protected against fungal attack with an effective amount of the composition of claim 1.

20. A method for improving plant health, comprising treating a plant propagation material of the plant, or a locus where the plant is growing or is to grow with an effective amount of composition of claim 1.

21. A process for preparing the composition of claim 1, comprising mixing the tolfenpyrad and pyraclostrobin with agriculturally acceptable formulation additives.