WO2020132797A1 - 一种针对补液的生理体征监测方法及监护设备 - Google Patents

一种针对补液的生理体征监测方法及监护设备 Download PDF

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Publication number
WO2020132797A1
WO2020132797A1 PCT/CN2018/123093 CN2018123093W WO2020132797A1 WO 2020132797 A1 WO2020132797 A1 WO 2020132797A1 CN 2018123093 W CN2018123093 W CN 2018123093W WO 2020132797 A1 WO2020132797 A1 WO 2020132797A1
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WIPO (PCT)
Prior art keywords
central venous
venous pressure
fluid replacement
interface
rehydration
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PCT/CN2018/123093
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English (en)
French (fr)
Inventor
卿磊
王澄
秦杰
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Priority to CN201880099383.9A priority Critical patent/CN112996436B/zh
Priority to PCT/CN2018/123093 priority patent/WO2020132797A1/zh
Publication of WO2020132797A1 publication Critical patent/WO2020132797A1/zh
Anticipated expiration legal-status Critical
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue

Definitions

  • the central venous pressure trend information displayed in the interface of the special tool for rehydration is refreshed.
  • the invention provides a monitoring device, including:
  • Memory stores program instructions
  • a processor the processor executes the program instructions to implement the following method steps:
  • the central venous pressure trend information displayed in the interface of the special tool for rehydration is refreshed.
  • the present invention provides a computer-readable storage medium including instructions, which when executed on a computer, causes the computer to perform the above-mentioned physiological sign monitoring method for fluid replacement.
  • 1 is a schematic flow chart of a method for monitoring physiological signs of fluid replacement
  • FIG. 2 is a schematic diagram of a hemodynamic monitoring interface of a monitoring device
  • FIG. 3 is a schematic diagram of a special tool interface of a monitoring device for fluid replacement
  • FIG. 4 is a schematic structural diagram of a monitoring device.
  • the CVP2-5 principle is a commonly used clinical judgment principle, that is, rapid rehydration of 100-200ml within 10 minutes. If the increase of CVP is less than 2mmHg, it indicates that the patient has volume responsiveness and can continue to rehydrate. When the CVP increases between 2-5mmHg, the fluid replacement needs to be suspended to observe whether the CVP can recover. When the CVP increase is greater than 5mmHg, it indicates that the patient is at risk of volume overload, and fluid replacement should be terminated.
  • the physiological sign monitoring method for fluid replacement in the present invention is described in detail below. It should be noted that the monitoring device mentioned in the present invention is not limited to the monitor, but also includes invasive/non-invasive ventilator, anesthesia machine, and Tremor, nurse station, central station, etc.
  • FIG. 1 is a schematic flowchart of a physiological sign monitoring method for fluid replacement in this embodiment, including:
  • the monitoring device can obtain the central venous pressure acquisition signal in the case of rehydration of the monitoring object through a measurement device connected to the human body, and the monitoring device can convert the collected signal of the central venous pressure in the case of rehydration of the monitoring object into Electrical signals, and pretreatment such as interference suppression, signal filtering and amplification, and finally the central venous pressure monitoring data under the condition of fluid replacement of the monitored object is finally obtained.
  • Central venous pressure is the pressure at which the superior and inferior vena cava enters the right atrium. It is measured by the superior, inferior vena cava or the right atrium internal tube. It reflects the right atrial pressure and is one of the main indicators for clinical observation of hemodynamics. In clinical practice, it is usually used as an indicator of fluid replacement rate and fluid replacement volume.
  • Step 102 Generate central venous pressure trend information based on central venous pressure monitoring data.
  • the central venous pressure trend information can display the monitoring data of the central venous pressure within a preset time period (for example, 30 minutes), and of course, it can also be set according to the actual situation, which is not specifically limited.
  • Step 103 Display a special tool interface for fluid replacement in the main monitoring interface.
  • the monitoring device may provide a main monitoring interface, and a special tool interface for displaying the condition of fluid replacement of the monitored object is generated on the main monitoring interface.
  • the main monitoring interface of conventional monitoring equipment will display various conventional physiological signs and waveform information. Medical personnel need to find CVP data that needs attention from the complicated information, so that medical personnel cannot intuitively and efficiently judge the fluid replacement situation. Get the data information you want to pay attention to.
  • a special tool interface for fluid replacement is displayed in the main monitoring interface, and the medical staff can intuitively obtain the desired CVP data information by observing the special tool interface .
  • the special tool interface for fluid supplementation can be popped out of the main monitoring interface after the user touches the CVP tool icon of the main monitoring interface.
  • FIG. 2 is a schematic diagram of a monitoring interface for hemodynamics of a monitoring device.
  • FIG. 3 is a schematic diagram of a special tool interface for fluid replacement in an embodiment of the present invention.
  • the monitoring interface receives the user's operation instructions, that is, the operation instructions for the "CVP 2-5" tool in area 201, and generates and displays a special tool interface for fluid replacement as shown in Figure 3.
  • the special tool interface for rehydration can be embedded in a display area of the main monitoring interface, or can be suspended on the main monitoring interface; the special tool interface for rehydration can cover or not cover other content displayed on the main monitoring interface .
  • Step 104 Display central venous pressure trend information in the interface of the special tool for fluid replacement.
  • the monitoring device can display the trend information of the central venous pressure of the monitored object in the special tool interface for fluid replacement after displaying the special tool interface for fluid replacement on the main monitoring interface.
  • the central venous pressure trend information may include at least one of a central venous pressure trend table and a central venous pressure trend chart. It can be understood that, in this embodiment, the central venous pressure of the monitored object is mainly displayed on the interface of a special tool for fluid replacement
  • the trend graph is explained as an example.
  • interface 301 is the above-mentioned special tool interface for rehydration
  • 302 is a trend graph of central venous pressure in the case of monitoring the subject to rehydration within a preset time period.
  • Step 105 Based on the acquired new central venous pressure monitoring data, refresh the central venous pressure trend information displayed in the interface of the special tool for fluid replacement.
  • the monitoring device can continue to monitor the center of the monitoring object through the measurement device after displaying the central venous pressure trend information on the special tool interface for fluid replacement.
  • the venous pressure is monitored in real time, and the central venous pressure trend information is generated, and the central venous pressure trend information displayed in the interface of the special tool for rehydration is refreshed according to the newly generated central venous pressure trend information. That is to say, the central venous pressure trend information in the interface of the special tool for fluid replacement always displays the latest central venous pressure trend information of the monitoring object acquired within a certain period of time (for example, within 30 minutes).
  • the central venous pressure trend chart can be used to generate and display the corresponding rehydration baseline of the monitored object, and the corresponding value of the rehydration baseline can also be set.
  • the measured value is used as the value corresponding to the rehydration baseline, or based on the configuration information entered by the user to determine the value corresponding to the rehydration baseline.
  • the first identification line and/or the second identification line may be generated and displayed on the central venous pressure trend map, the first identification The line and the second identification line are associated with the fluid replenishment baseline, and the value corresponding to the first identification line is less than the value corresponding to the second identification line, and the value corresponding to the fluid replenishment baseline is less than the value corresponding to the first identification line. That is to say, the two marking lines set on the basis of the fluid replacement baseline when the first marking line and the second marking line are understood, the values corresponding to the first marking line and the second marking line can also be based on The configuration information entered by the user is determined. The following is explained in conjunction with FIG. 3:
  • 302 is the trend graph of central venous pressure under the condition of rehydration of the monitoring object
  • 303 is the baseline of the rehydration corresponding to the monitoring object
  • 304 is the first marking line
  • 305 is the second marking line, where the first marking line and The second marking line is associated with the setting of the rehydration baseline.
  • the value corresponding to the first marking line is the value corresponding to the rehydration baseline + 2 mmHg, that is, 2 mmHg is added to the value corresponding to the rehydration baseline;
  • the second marking line corresponds to The value is the value corresponding to the baseline of rehydration +5mmHg, that is, add 5mmHg to the value corresponding to the baseline of rehydration.
  • the values corresponding to the fluid replenishment baseline, the first marking line and the second marking line can be set by the doctor or nurse according to the actual situation of the monitored object. The above is only an example and does not mean that the first marking line and the second marking line The limit of the value corresponding to the second marking line.
  • the following describes how to judge the rehydration situation of the monitored object based on the central venous pressure trend information of the monitored object and based on the rehydration baseline and the first marking line and/or the second marking line.
  • the monitoring device can measure the measured value of the central venous pressure of the monitored object in real time through the measuring device and determine that when the measured value of the central venous pressure of the monitored object exceeds the value corresponding to the first identification line, the first prompt information is generated; and/or It is determined that when the measured value of the central venous pressure of the monitored object exceeds the value corresponding to the second identification line, second prompt information that is different from the first prompt information is generated.
  • the first prompt information includes notification information indicating that the rehydration of the monitoring object needs to be suspended
  • the second prompt information includes notification information indicating that the rehydration of the monitoring object needs to be terminated.
  • the monitoring device can obtain the central venous pressure trend information of the monitored object in real time, and perform a trend graph (see 302 in FIG. 3) in the special tool interface of the rehydration situation Display, and the first marking line (refer to 304 in FIG. 3) and the second marking line (refer to 305 in FIG. 3) are also displayed on the special tool interface for fluid replacement, according to the measured value of the central venous pressure of the monitored object and The first marking line or the second marking line intersects to give a prompt message.
  • the first marking line is the value corresponding to the rehydration baseline +2mmHg
  • the second marking line is the value corresponding to the rehydration baseline +5mmHg as an example:
  • a first prompt message is issued, which A prompt message prompts to suspend rehydration of the monitored object;
  • a second prompt message is issued.
  • the second prompt message instructs to terminate the rehydration of the monitored object.
  • the monitoring device may generate a waveform diagram and/or numerical information corresponding to the physiological sign associated with the fluid replacement condition based on the physiological sign monitoring data associated with the fluid replacement condition, and Display the waveform graph and/or numerical information corresponding to the physiological signs associated with the fluid replacement status on the interface of the special tool for rehydration status, and refresh and display them in the interface of the dedicated tool for fluid replacement status based on the acquired new physiological sign monitoring data associated with the fluid rehydration status Waveforms and/or numerical information corresponding to physiological signs associated with fluid replacement.
  • FIG. 3 is the heart rate trend graph under the condition of rehydration within the preset time of the monitoring object
  • 308 is the rehydration situation of the monitoring object
  • Real-time numerical information of the heart rate such as "65” shown in Figure 3
  • 307 is the arterial pressure trend graph under the condition of rehydration within the preset time of the monitoring object
  • 309 is the real-time numerical information of the arterial pressure under the condition of rehydration of the monitoring object (For example, "130/80" shown in Figure 3)
  • there are other changes in the monitoring data of physiological signs related to the monitoring subject's fluid replacement status (not shown in Figure 3).
  • the process of monitoring the physiological characteristics of the monitoring object associated with the fluid replacement situation of the monitoring device is similar to the process of monitoring the central venous pressure monitoring data described above. The above has been specifically described, and the details will not be repeated here.
  • the interface of the dedicated tool for rehydration displays at least a central venous pressure trend graph and/or a waveform graph corresponding to the physiological characteristics associated with the fluid rehydration status (the waveform graph includes a physiological sign analog signal waveform graph and a physiological sign trend graph)
  • the trend graph and the waveform graph are marked by the same coordinate system, and the time axes of the two are consistent. The following describes the operation of the special tool interface in response to the user's fluid replacement:
  • the user performs operations on the monitor of the monitoring device, and the monitoring device generates corresponding operation instructions, and in response to the operation instructions, generates and displays a timeline in the trend graph and/or waveform graph, and displays central venous pressure and/or fluid replacement The measured values of the physiological signs associated with the situation at the time points corresponding to the timeline.
  • the operation of the user in the special tool interface of the fluid replenishment situation includes at least one of gesture operation, sliding operation, click operation, and voice control operation.
  • the monitoring device may receive the click Operation, at this time, the click operation generates an operation instruction, that is, the operation instruction can be defined in advance, for example, the slide operation display timeline and the measured values of the time points corresponding to the display timeline can be defined in advance (such as left slide operation, right slide Operation, slide-up operation, slide-down operation, etc.), or define the click operation to display the timeline and the measured values at the time points corresponding to the timeline (eg click the trend graph and/or waveform graph, double-click the trend graph and/or waveform graph Operation, etc.), or define the gesture operation to display the timeline and the measured values at the time points corresponding to the display timeline (such as swinging the wrist or arm to the left, swinging the wrist or arm to the right, such as the four-finger contraction operation or three fingers Slide operation, etc
  • the monitoring device can monitor the monitoring data of the central venous pressure of the monitoring object in real time during the rehydration of the monitoring object, and generate the central venous pressure according to the monitoring data of the central venous pressure Trend information, and display it on the special tool interface for rehydration, and display the rehydration baseline and the first marking line and/or second marking line in the special tool interface for rehydration, and according to the measured value of the central venous pressure at the current time of the monitoring object Prompt message is sent from the intersection with the first marking line and/or the second marking line to assist the doctor or nurse to rehydrate the monitored object, which is used to improve the prior art.
  • the doctor performs liquid therapy on the target object, he needs to watch and Record changes in the patient's central venous pressure parameters, and determine whether to terminate fluid therapy based on the parameter changes.
  • a monitoring device has an independent housing with a sensor interface area on the housing panel, in which multiple sensor interfaces are integrated to connect with various external physiological sign sensor accessories 411.
  • the housing panel also includes a small LCD display area, a display 419, Input interface circuit 422 and alarm circuit 420 (such as LED alarm area) and so on.
  • the parameter processing module is used for external communication and power interface for communicating with the host and taking power from the host.
  • the parameter processing module also supports extrapolated parameter modules.
  • the plug-in monitor host can be formed by inserting the parameter module as a part of the monitor, or connected to the host through a cable.
  • the extrapolated parameter module is used as an external accessory of the monitor.
  • the internal circuit of the parameter processing module is placed in the housing, as shown in FIG. 4, and includes at least two signal acquisition circuits 412 corresponding to physiological parameters, a front-end signal processing circuit 413, and a main processor 415.
  • the signal acquisition circuit 412 may be selected from Electrical circuits, breathing circuits, body temperature circuits, blood oxygen circuits, non-invasive blood pressure circuits, invasive blood pressure circuits, etc. These signal acquisition circuits 412 are electrically connected to corresponding sensor accessories for electrical connection to sensors corresponding to different physiological parameters Attachment 411, the output of which is coupled to the front-end signal processor.
  • the communication port of the front-end signal processor is coupled to the main processor.
  • the main processor 415 is electrically connected to the external communication and power interface 416 (the main processor 415 is connected to the external communication and power interface 416 can also include a power supply and battery management circuit 417).
  • Various physiological parameter measurement circuits can use the common circuit in the prior art.
  • the front-end signal processor completes the sampling and analog-to-digital conversion of the signal acquisition circuit output signal, and outputs the control signal to control the physiological signal measurement process. These parameters include but are not limited to : ECG, respiration, body temperature, blood oxygen, noninvasive blood pressure and invasive blood pressure parameters.
  • the front-end signal processor can be implemented by a single-chip microcomputer or other semiconductor devices, or by ASIC or FPGA.
  • the front-end signal processor can be powered by an isolated power supply.
  • the sampled data is sent to the main processor through the isolated communication interface.
  • the front-end signal processor circuit can be coupled to the main processor 415 through the isolated power supply and the communication interface 414 .
  • the reason why the front-end signal processor is powered by the isolated power supply is that the DC/DC power supply isolated by the transformer plays the role of isolating the patient from the power supply equipment.
  • the main purposes are: 1. Isolating the patient, floating the application part through the isolation transformer, so that The patient leakage current is small enough; 2. Prevent the voltage or energy during the application of defibrillation or electrocautery from affecting the cards and devices of the intermediate circuit such as the main control board (guaranteed by creepage distance and electrical clearance).
  • the main processor completes the calculation of physiological parameters, and sends the calculation results and waveforms of the parameters to the host (such as a host with a display, a PC, a central station, etc.) through external communication and power interface.
  • the external communication and power interface 416 can be Ethernet (Ethernet), Token Ring (Token Ring), Token Bus (Token Bus), and one or a combination of the LAN interfaces composed of the fiber distribution data interface (FDDI) as the backbone of the three types of networks. It is one or a combination of wireless interfaces such as infrared, Bluetooth, wifi, and WMTS communication, or one or a combination of wired data connection interfaces such as RS232 and USB.
  • the external communication and power interface 416 may also be one or a combination of two of a wireless data transmission interface and a wired data transmission interface.
  • the host computer can be any computer equipment such as the host computer of the monitor, the electrocardiograph, the ultrasound diagnostic apparatus, and the computer. By installing the matched software, a monitor device can be formed.
  • the host can also be a communication device, such as a mobile phone, and the parameter processing module sends data to a mobile phone that supports Bluetooth communication through a Bluetooth interface to realize remote transmission of data.
  • the display 419 is configured to display information
  • the memory 418 stores program instructions, and the main processor 415 implements the following method steps when executing the program instructions stored in the memory 418:
  • the central venous pressure trend information displayed in the interface of the special tool for rehydration is refreshed.
  • the central venous pressure trend information includes at least one of a central venous pressure trend table and a central venous pressure trend graph.
  • At least the central venous pressure trend graph is displayed in the interface of the special tool for fluid replacement, and the processor is further configured to implement:
  • main processor 415 is further configured to implement:
  • a value corresponding to the fluid replacement baseline is determined.
  • main processor 415 is further configured to implement:
  • the first marking line, the second marking line and the rehydration baseline have an association relationship, and the first The value corresponding to an identification line is smaller than the value corresponding to the second identification line, and the value corresponding to the rehydration baseline is smaller than the value corresponding to the first identification line.
  • the main processor is further configured to: when it is determined that the measured value of the central venous pressure of the monitored object exceeds the value corresponding to the first identification line, generate first prompt information; and/or When it is determined that the measured value of the central venous pressure of the monitoring object exceeds the value corresponding to the second identification line, second prompt information different from the first prompt information is generated.
  • the first prompt information includes notification information indicating that the rehydration of the monitored object needs to be suspended
  • the second prompt information includes notification information indicating that the rehydration of the monitored object needs to be terminated.
  • the main processor 415 is further configured: the value corresponding to the first identification line and the value corresponding to the second identification line are determined based on configuration information input by the user.
  • main processor 415 is further configured to implement:
  • physiological signs associated with the condition of fluid replacement of the monitored object include one or more of heart rate, arterial pressure, non-invasive blood pressure, blood oxygen, and blood perfusion index;
  • the main processor 415 is further configured to implement:
  • a timeline is generated and displayed in the trend graph and/or waveform graph
  • the measured values of the central venous pressure and/or the physiological signs associated with the fluid replacement situation at the time points corresponding to the time line are displayed.
  • the monitoring device can monitor the monitoring data of the central venous pressure of the monitoring object in real time during the rehydration of the monitoring object, and generate the central venous pressure according to the monitoring data of the central venous pressure Trend information, and display it on the special tool interface of the rehydration situation, at the same time display the rehydration baseline and the first marking line and/or the second marking line on the special tool interface of the rehydration situation, and according to the measured value of the central venous pressure at the current time of the monitoring object Prompt message is sent from the intersection with the first marking line and/or the second marking line to assist the doctor or nurse to rehydrate the monitored object, which is used to improve the prior art.
  • the doctor performs liquid therapy on the target object, he needs to watch and Record changes in the patient's central venous pressure parameters, and determine whether to terminate fluid therapy based on the parameter changes.
  • the embodiments of the present invention may be provided as methods, systems, or computer program products. Therefore, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment, or an embodiment combining software and hardware. Moreover, the present invention may take the form of a computer program product implemented on one or more computer usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) containing computer usable program code.
  • computer usable storage media including but not limited to disk storage, CD-ROM, optical storage, etc.
  • each flow and/or block in the flowchart and/or block diagram and a combination of the flow and/or block in the flowchart and/or block diagram may be implemented by computer program instructions.
  • These computer program instructions can be provided to the processor of a general-purpose computer, special-purpose computer, embedded processing machine, or other programmable data processing device to produce a machine that enables the generation of instructions executed by the processor of the computer or other programmable data processing device
  • These computer program instructions may also be stored in a computer readable memory that can guide a computer or other programmable data processing device to work in a specific manner, so that the instructions stored in the computer readable memory produce an article of manufacture including an instruction device, the instructions
  • the device implements the functions specified in one block or multiple blocks of the flowchart one flow or multiple flows and/or block diagrams.
  • These computer program instructions can also be loaded onto a computer or other programmable data processing device, so that a series of operating steps are performed on the computer or other programmable device to produce computer-implemented processing, which is executed on the computer or other programmable device
  • the instructions provide steps for implementing the functions specified in one block or multiple blocks of the flowchart one flow or multiple flows and/or block diagrams.
  • the computing device includes one or more processors (CPUs), input/output interfaces, network interfaces, and memory.
  • processors CPUs
  • input/output interfaces network interfaces
  • memory volatile and non-volatile memory
  • the memory may include non-permanent memory, random access memory (RAM) and/or non-volatile memory in a computer-readable medium, such as read only memory (ROM) or flash memory (flash RAM).
  • RAM random access memory
  • ROM read only memory
  • flash RAM flash memory
  • Computer readable media including permanent and non-permanent, removable and non-removable media, can store information by any method or technology.
  • the information may be computer readable instructions, data structures, modules of programs, or other data.
  • Examples of computer storage media include, but are not limited to, phase change memory (PRAM), static random access memory (SRAM), dynamic random access memory (DRAM), other types of random access memory (RAM), read-only memory (ROM), electrically erasable programmable read-only memory (EEPROM), flash memory or other memory technologies, read-only compact disc read-only memory (CD-ROM), digital versatile disc (DVD) or other optical storage, Magnetic tape cartridges, magnetic tape storage or other magnetic storage devices or any other non-transmission media can be used to store information that can be accessed by computing devices.
  • computer-readable media does not include temporary computer-readable media (transitory media), such as modulated data signals and carrier waves.
  • the embodiments of the present invention may be provided as methods, systems, or computer program products. Therefore, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment or an embodiment combining software and hardware. Moreover, the present invention may take the form of a computer program product implemented on one or more computer usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) containing computer usable program code.
  • computer usable storage media including but not limited to disk storage, CD-ROM, optical storage, etc.

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Abstract

一种针对补液的生理体征监测方法，包括：获取监测对象补液情况下中心静脉压监测数据；根据中心静脉压监测数据，生成中心静脉压趋势信息；在主监测界面内显示补液情况专用工具界面；在补液情况专用工具界面内显示中心静脉压趋势信息；基于获取到的新的中心静脉压监测数据，刷新显示在补液情况专用工具界面内的中心静脉压趋势信息。

Description

一种针对补液的生理体征监测方法及监护设备 技术领域
本发明涉及医疗设备领域，特别涉及一种针对补液的生理体征监测方法及监护设备。
背景技术
医生在对病人进行补液时经常会通过测量病人中心静脉压力(central venous pressure，CVP)的情况来判断病人是否存在容量反应性以及是否存在容量过负荷的风险。CVP是指右心房及上、下腔静脉胸腔段的压力。它可判断病人血容量、心功能与血管张力的综合情况，有别于周围静脉压力。
当前临床上，监护仪仅能提供的CVP参数的实时测量，医生在补液时需要自己在监护仪的主监测界面上，从众多参数波形信息中找到CVP的波形数据，并根据自己的经验，主观判断补液过程中CVP的变化情况决定是否继续补液或停止补液，非常不便。
发明内容
根据本发明的第一方面，本发明提供了一种针对补液的生理体征监测方法，包括：
获取监测对象补液情况下中心静脉压监测数据；
根据所述中心静脉压监测数据，生成中心静脉压趋势信息；
在主监测界面内显示补液情况专用工具界面；
在所述补液情况专用工具界面内显示所述中心静脉压趋势信息；
基于获取到的新的中心静脉压监测数据，刷新显示在所述补液情况专用工具界面内的中心静脉压趋势信息。
根据本发明的第二方面，本发明提供了一种监护设备，包括：
显示器，所述显示器配置为显示信息；
存储器，所述存储器存储有程序指令；
处理器，所述处理器执行所述程序指令实现下面方法步骤：
获取监测对象补液情况下中心静脉压的监测数据；
根据所述中心静脉压监测数据，生成中心静脉压趋势信息；
在主监测界面内显示补液情况专用工具界面；
在所述补液情况专用工具界面内显示所述中心静脉压趋势信息；
基于获取到的新的中心静脉压监测数据，刷新显示在所述补液情况专用工具界面内的中心静脉压趋势信息。
根据本发明的第三方面，本发明提供了一种计算机可读存储介质，包括指令，当所述指令在计算机上运行时，使得计算机执行上述针对补液的生理体征监测方法。
附图说明
图1为一种针对补液的生理体征监测方法的流程示意图；
图2为一种监护设备的血流动力学的监测界面的示意图；
图3为一种监护设备的补液情况专用工具界面的示意图；
图4为一种监护设备的结构示意图。
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。
本发明的说明书和权利要求书及上述附图中的术语“第一”、“第二”、“第三”、“第四”等(如果存在)是用于区别类似的对象，而不必用于描述特定的顺序或先后次序。应该理解这样使用的数据在适当情况下可以互换，以便这里描述的实施例能够以除了在这里图示或描述的内容以外的顺序实施。此外，术语“包括”和“具有”以及他们的任何变形，意图在于覆盖不排他的包含，例如，包含了一系列步骤或单元的过程、方法、系统、产品或设备不必限于清楚地列出的那些步骤或单元，而是可包括没有清楚地列出的或对于这些过程、方法、产品或设备固有的其它步骤或单元。
CVP2-5原则是临床上常用的判断原则，即：在10分钟内快速补液 100-200ml，如果CVP增高小于2mmHg，则表明病人存在容量反应性，可以继续补液。当CVP增高在2-5mmHg之间时，需要暂停补液，观察CVP能否恢复。当CVP增高大于5mmHg，则表明病人存在容量过负荷风险，应该终止补液。
下面对本发明中针对补液的生理体征监测方法进行详细描述，需要说明的是，本发明提及的监护设备，不仅限于监护仪，也包括具有监护功能的有创/无创呼吸机、麻醉机、除颤仪、护士站、中央站等。
请参阅图1，图1为本实施例中针对补液的生理体征监测方法的流程示意图，包括：
步骤101、获取监测对象补液情况下中心静脉压监测数据。
本实施例中，监护设备可以通过与人体连接的测量装置获取监测对象补液情况下的中心静脉压的采集信号，监护设备可以将获取到监测对象在补液情况下的中心静脉压的采集信号转换为电信号，并进行干扰抑制、信号滤波和放大等预处理，最终获取到监测对象补液情况下的中心静脉压监测数据。
中心静脉压是上、下腔静脉进入右心房处的压力，通过上、下腔静脉或右心房内置管测得，它反映右房压，是临床观察血液动力学的主要指标之一。在临床上通常作为补液速度和补液量的指标。
步骤102、根据中心静脉压监测数据，生成中心静脉压趋势信息。
本实施例中，监护设备在通过与人体连接的测量装置获取监测对象在补液情况下的中心静脉压数据之后，由于监测对象在补液情况下中心静脉压监测数据通常会随着时间的推移不断变化，因此，监护设备可以存储预设时间段内获得的监测对象在补液情况下的中心静脉压监测数据，以此来得到监测对象的中心静脉压趋势信息。
需要说明的是，该中心静脉压趋势信息可以显示中心静脉压在预设时间段(例如30分钟)内的监测数据，当然也可以是根据实际情况进行设置，具体不做限定。
步骤103、在主监测界面内显示补液情况专用工具界面。
本实施例中，监护设备可以提供主监测界面，并在主监测界面上生成用于显示监测对象补液情况专用工具界面。
通常的，常规的监护设备的主监测界面会显示各种常规的生理体征波形信 息，医护人员需要从繁杂的信息中找到需要关注的CVP数据，使得医护人员在判断补液情况时不能直观、高效地得到想要关注的数据信息。而本实施例中，当医护人员需要关注CVP的数据信息时，在主监测界面内显示一补液情况专用工具界面，医护人员通过观察该专用工具界面即可直观地获取所想要的CVP数据信息。具体的，补液情况专用工具界面可以通过用户触摸主监测界面的CVP工具图标后，从主监测界面中弹出。
例如，请参阅图2，图2为一种监护设备的血流动力学的监测界面的示意图，图3为本发明一种实施例中补液情况专用工具界面的示意图，其中可以在血流动力学的监测界面接收用户的操作指令，即对201区域“CVP 2-5 tool”的操作指令，生成并显示如图3所示的补液情况专用工具界面。
可以理解的是，补液情况专用工具界面可以是嵌入于主监测界面的一个显示区域，也可以悬浮于主监测界面上；补液情况专用工具界面覆盖或不覆盖除主监测界面上所显示的其他内容。
步骤104、在补液情况专用工具界面内显示中心静脉压趋势信息。
本实施例中，监护设备在主监测界面显示补液情况专用工具界面之后，可以将该监测对象的中心静脉压趋势信息在补液情况专用工具界面内显示。其中该中心静脉压趋势信息可以包括中心静脉压趋势表、中心静脉压趋势图中的至少一种，可以理解的是，本实施例中，主要以补液情况专用工具界面显示监测对象的中心静脉压趋势图在为例进行说明。
继续参阅图3，界面301即为上述所说的补液情况专用工具界面，302为预设时间段内监测对象补液情况下的中心静脉压趋势图。
步骤105、基于获取到的新的中心静脉压监测数据，刷新显示在补液情况专用工具界面内的中心静脉压趋势信息。
本实施例中，由于监测对象在补液情况下的中心静脉压监测数据是实时变化的，因此可以在补液情况专用工具界面显示中心静脉压趋势信息之后，监护设备继续通过测量装置对监测对象的中心静脉压进行实时监测，并生成中心静脉压趋势信息，并根据新生成的中心静脉压趋势信息刷新显示在补液情况专用工具界面内的中心静脉压趋势信息。也就是说，补液情况专用工具界面内的中心静脉压趋势信息始终显示的是最新的一段时间内(例如30分钟内)获取到 的监测对象的中心静脉压趋势信息。
为了辅助医护人员对补液情况的判断，可以在中心静脉压趋势图上生成并显示监测对象对应的补液基线，还可以设置补液基线对应的数值，例如可以将打开补液情况专用工具界面时中心静脉压的测量值作为补液基线对应的数值，或者基于用户输入的配置信息确定补液基线对应的数值。
可以理解的是，在中心静脉压趋势图上生成并显示监测对象对应的补液基线之后，可以在中心静脉压趋势图中生成并显示第一标识线和/或第二标识线，该第一标识线、第二标识线与补液基线具有关联关系，且该第一标识线对应的数值小于第二标识线对应的数值，补液基线对应的数值小于第一标识线对应的数值。也就是说，该第一标识线以及第二标识线时在补液基线的基础上进行设置的两条标识线，可以理解的是，该第一标识线以及第二标识线对应的数值同样可以基于用户输入的配置信息确定。下面结合图3进行说明：
请参阅图3，302为监测对象补液情况下的中心静脉压趋势图，303为监测对象对应的补液基线，304为第一标识线，305为第二标识线，其中，该第一标识线以及第二标识线与补液基线的设置具有关联关系，例如该第一标识线对应的数值为补液基线对应的数值+2mmHg，也即在补液基线对应的数值的基础上加2mmHg；第二标识线对应的数值为补液基线对应的数值+5mmHg，也即在补液基线对应的数值的基础上加5mmHg。可以理解的是，补液基线、第一标识线以及第二标识线对应的数值可以由医生或护士根据监测对象的实际情况自行设置，上述仅为举例说明，并不代表对第一标识线以及第二标识线对应的数值的限定。
下面说明如何通过监测对象的中心静脉压趋势信息，并基于补液基线，以及第一标识线和/或第二标识线对监测对象的补液情况进行判断。
该监护设备可以通过测量装置实时测量监测对象的中心静脉压的测量值，并确定当监测对象的中心静脉压的测量值超过第一标识线对应的数值时，生成第一提示信息；和/或，确定当监测对象的中心静脉压的测量值超过第二标识线对应的数值时，生成区别与第一提示信息的第二提示信息。其中：该第一提示信息包括表示需要暂停对监测对象进行补液的通知信息，该第二提示信息包括表示需要终止对监测对象进行补液的通知信息。
继续参阅图3，在对监测对象进行补液的过程中，监护设备可以实时获取监测对象的中心静脉压趋势信息，并在补液情况专用工具界面以趋势图(参阅图3中的302)的形式进行展示，且第一标识线(参阅图3中的304)以及第二标识线(参阅图3中的305)同样在补液情况专用工具界面进行显示，可以根据监测对象的中心静脉压的测量值与第一标识线或第二标识线的相交情况发出提示信息，下面以第一标识线为补液基线对应的数值+2mmHg，第二标识线为补液基线对应的数值+5mmHg为例进行说明：
若当前时刻监测对象的中心静脉压的测量值超过第一标识线时，即当前时刻监测对象的中心静脉压的测量值高于补液基线对应的数值+2mmHg，则发出第一提示信息，该第一提示信息提示暂停对监测对象进行补液；
若当前时刻监测对象的中心静脉压的测量值超过第二标识线时，即当前时刻监测对象的中心静脉压的测量值高于补液基线对应的数值+5mmHg，则发出第二提示信息，该第二提示信息指示对监测对象终止补液。
需要说明的是，监护设备除了获取监测对象在补液情况下的中心静脉压监测数据，还可以获取监测对象与补液情况关联的生理体征监测数据，该与补液情况关联的生理体征至少包括心率、动脉压(Art)、无创血压(NIBP)、血氧以及血流灌注指数中的一种。具体的，显示的血氧监测数据可以是血氧饱和度趋势图、血氧饱和度测量值等。
另外，监护设备在监测到监测对象与补液情况关联的生理体征监测数据之后，可以基于与补液情况关联的生理体征监测数据生成与补液情况关联的生理体征对应的波形图和/或数值信息，并在补液情况专用工具界面显示与补液情况关联的生理体征对应的波形图和/或数值信息，以及基于获取到的新的与补液情况关联的生理体征监测数据，刷新显示在补液情况专用工具界面内与补液情况关联的生理体征对应的波形图和/或数值信息。
下面结合图3，以与补液情况关联的生理体征为心率和动脉压为例进行说明，请参阅图3，306为监测对象预设时长内补液情况下的心率趋势图，308为监测对象补液情况下的心率的实时数值信息(例如图3中显示的“65”)，307为监测对象预设时长内补液情况下的动脉压趋势图，309为监测对象补液情况下的动脉压的实时数值信息(例如图3中显示的“130/80”)，当然也还有其他 与监测对象补液情况相关的生理体征的监测数据的变化(图3中未示出)，为了描述简便，不再一一进行说明。可以理解的是，监护设备在监护监测对象与补液情况关联的生理特征的过程与上述监测中心静脉压监测数据的过程类似，上述已经进行了具体说明，具体此处不再赘述。
还需要说明的是，当补液情况专用工具界面至少显示中心静脉压趋势图和/或与补液情况关联的生理特征对应的波形图(波形图包括生理体征模拟信号波形图和生理体征趋势图)时，还可以响应用户在补液情况专用工具界面的操作，在趋势图和/或波形图中生成并显示时间线，且显示中心静脉压和/或与补液情况关联的生理体征在时间线对应的时间点的测量值。可以理解的是，该趋势图以及波形图采用同样的坐标系进行标识，两者的时间轴是一致的。下面对响应于用户在补液情况专用工具界面的操作进行说明：
用户在监护设备的显示器上进行操作，监护设备生成对应的操作指令，并响应于该操作指令，在趋势图和/或波形图中生成并显示时间线，且显示中心静脉压和/或与补液情况关联的生理体征在时间线对应的时间点的测量值。
可以理解的是，用户在补液情况专用工具界面中的操作至少包括手势操作、滑动操作、点击操作以及声控操作中的一种，例如当用户对显示器进行点击操作时，监护设备可以接收到该点击操作，此时，该点击操作即生成操作指令，也就是说，可以提前定义操作指令，例如提前定义滑动操作显示时间线以及显示时间线对应的时间点的测量值(如左滑操作、右滑操作、上滑操作以及下滑操作等等)，或者定义点击操作显示时间线以及显示时间线对应的时间点的测量值(如单击趋势图和/或波形图，双击趋势图和/或波形图的操作等等)，或者定义手势操作显示时间线以及显示时间线对应的时间点的测量值(如向左摆动手腕或手臂，向右摆动手腕或手臂，如四根手指收缩操作或者三根手指上滑操作等等)，或者定义声控操作为显示时间线以及时间线对应的时间点的测量值(如收到显示的声音即显示时间线以及时间线对应的时间点的测量值)，上述仅为举例说明，并不代表对用户在补液情况专用工具界面中的操作的限定。
综上所述，可以看出，本发明实施例中，监护设备可以在对监测对象进行补液的过程中，实时监测监护对象的中心静脉压监测数据，并根据中心静脉压 监测数据生成中心静脉压趋势信息，并在补液情况专用工具界面进行显示，同时在补液情况专用工具界面中显示补液基线以及第一标识线和/或第二标识线，并根据监测对象当前时刻的中心静脉压的测量值与第一标识线和/或第二标识线的相交关系发出提示信息，辅助医生或护士对监护对象进行补液，用于改善现有技术中医生在对目标对象进行液体治疗时，需要自己观看并记录病人的中心静脉压参数变化，并根据参数变化判断是否需要终止液体治疗。
上面从针对补液的生理体征监测方法的角度对本发明实施例进行描述，下面从监护设备的角度对本发明实施例进行描述。
如图4所示，提供了一种监护设备。该监护设备具有独立的外壳，外壳面板上具有传感器接口区，其中集成了多个传感器接口，用于与外部的各个生理体征传感器附件411连接，外壳面板上还包括小型IXD显示器区，显示器419，输入接口电路422和报警电路420(如LED报警区)等。参数处理模块用于与主机进行通讯和从主机取电的对外通讯和电源接口。参数处理模块还支持外插参数模块，可以通过插入参数模块形成插件式监护仪主机，作为监护仪的一部分，也可以通过电缆与主机连接，外插参数模块作为监护仪外置的一个配件。
参数处理模块的内部电路置于外壳内，如图4所示，包括至少两个生理参数对应的信号采集电路412、前端信号处理电路413和主处理器415，信号采集电路412可以选自于心电电路、呼吸电路、体温电路、血氧电路、无创血压电路、有创血压电路等等，这些信号采集电路412分别与相应的传感器附件电连接，用于电连接到不同的生理参数对应的传感器附件411，其输出端耦合到前端信号处理器，前端信号处理器的通讯口耦合到主处理器，主处理器415与对外通讯和电源接口416电连接(主处理器415与对外通讯和电源接口416之间还可以包括电源和电池管理电路417)。各种生理参数测量电路可采用现有技术中的通用电路，前端信号处理器完成信号采集电路输出信号的采样和模数转换，并输出控制信号控制生理信号的测量过程，这些参数包括但不限于：心电，呼吸，体温，血氧，无创血压和有创血压参数。前端信号处理器可采用单片机或其它半导体器件实现，也可以采用ASIC或FPGA实现。前端信号处理器可由隔离电源供电，采样得到的数据经过简单处理打包后，通过隔离通讯接口发送至主处理器，例如前端信号处理器电路可以通过隔离电源和通讯接口414耦合到主处理器415上。前端信号处理器由隔离电源供电的原因是通过变 压器隔离的DC/DC电源，起到了隔离患者与供电设备的作用，主要目的是：1、隔离患者，通过隔离变压器，将应用部分浮地，使患者漏电流足够小；2、防止除颤或电刀应用时的电压或能量影响主控板等中间电路的板卡及器件(用爬电距离和电气间隙保证)。主处理器完成生理参数的计算，并通过对外通讯和电源接口将参数的计算结果和波形发送到主机(如带显示器的主机、PC机、中央站等等)，对外通讯和电源接口416可以是以太网(Ethernet)、令牌环(Token Ring)、令牌总线(Token Bus)以及作为这三种网的骨干网光纤分布数据接口(FDDI)构成的局域网接口中的一个或其组合，还可以是红外、蓝牙、wifi、WMTS通讯等无线接口中的一个或其组合，或者还可以是RS232、USB等有线数据连接接口中的一个或其组合。对外通讯和电源接口416也可以是无线数据传输接口和有线数据传输接口中的一种或两种的组合。主机可以是监护仪的主机、心电图机，超声诊断仪，计算机等任何一个计算机设备，安装配合的软件，就能够组成一个监护设备。主机还可以是通讯设备，例如手机，参数处理模块通过蓝牙接口将数据发送到支持蓝牙通讯的手机上，实现数据的远程传输。
其中，显示器419配置为显示信息；
存储器418存储有程序指令，主处理器415执行存储器418中存储的程序指令时实现下面方法步骤：
获取监测对象补液情况下中心静脉压的监测数据；
根据所述中心静脉压监测数据，生成中心静脉压趋势信息；
在主监测界面内显示补液情况专用工具界面；
在所述补液情况专用工具界面内显示所述中心静脉压趋势信息；
基于获取到的新的中心静脉压监测数据，刷新显示在所述补液情况专用工具界面内的中心静脉压趋势信息。
在一个实施例中，所述中心静脉压趋势信息包括中心静脉压趋势表、中心静脉压趋势图中的至少一种。
在一个实施例中，在所述补液情况专用工具界面内至少显示所述中心静脉压趋势图，所述处理器还配置为实现：
在所述中心静脉压趋势图中生成并显示所述监测对象对应的补液基线。
在一个实施例中，所述主处理器415还配置为实现：
在所述中心静脉压趋势图中生成并显示所述监测对象对应的补液基线之前，基于打开所述补液情况专用工具界面时的中心静脉压的测量值来确定所述补液基线对应的数值；
或者，基于用户输入的配置信息确定所述补液基线对应的数值。
在一个实施例中，所述主处理器415还配置为实现：
在所述中心静脉压趋势图中生成并显示第一标识线和/或第二标识线，所述第一标识线、所述第二标识线与所述补液基线具有关联关系，且所述第一标识线对应的数值小于所述第二标识线对应的数值，所述补液基线对应的数值小于所述第一标识线对应的数值。
在一个实施例中，所述主处理器还配置为实现：确定到所述监测对象的中心静脉压的测量值超过所述第一标识线对应的数值时，生成第一提示信息；和/或，确定到所述监测对象的中心静脉压的测量值超过所述第二标识线对应的数值时，生成区别于第一提示信息的第二提示信息。
在一个实施例中，所述第一提示信息包括表示需要暂停对所述监测对象进行补液的通知信息，所述第二提示信息包括表示需要终止对所述监测对象进行补液的通知信息。
在一个实施例中，所述主处理器415还配置为：所述第一标识线对应的数值和所述第二标识线对应的数值基于用户输入的配置信息确定。
在一个实施例中，所述主处理器415还配置为实现：
获取所述监测对象与补液情况关联的生理体征监测数据，所述与补液情况关联的生理体征包括心率、动脉压、无创血压、血氧、血流灌注指数中的一种或多种；
基于所述与补液情况关联的生理体征监测数据生成与补液情况关联的生理体征对应的波形图和/或数值信息；
在所述补液情况专用工具界面显示所述与补液情况关联的生理体征对应的波形图和/或数值信息；
基于获取到的新的与补液情况关联的生理体征监测数据，刷新显示在所述补液情况专用工具界面内与补液情况关联的生理体征对应的波形图和/或数值信息。
在一个实施例中，当所述补液情况专用工具界面至少显示中心静脉压趋势图和/或所述与补液情况关联的生理体征对应的波形图时，所述主处理器415还配置为实现：
响应用户在所述补液情况专用工具界面中的操作，在所述趋势图和/或波形图中生成并显示一时间线；
显示所述中心静脉压和/或所述与补液情况关联的生理体征在所述时间线对应的时间点的测量值。
综上所述，可以看出，本发明实施例中，监护设备可以在对监测对象进行补液的过程中，实时监测监护对象的中心静脉压监测数据，并根据中心静脉压监测数据生成中心静脉压趋势信息，并在补液情况专用工具界面进行显示，同时在补液情况专用工具界面中显示补液基线以及第一标识线和/或第二标识线，并根据监测对象当前时刻的中心静脉压的测量值与第一标识线和/或第二标识线的相交关系发出提示信息，辅助医生或护士对监护对象进行补液，用于改善现有技术中医生在对目标对象进行液体治疗时，需要自己观看并记录病人的中心静脉压参数变化，并根据参数变化判断是否需要终止液体治疗。
本领域内的技术人员应明白，本发明的实施例可提供为方法、系统、或计算机程序产品。因此，本发明可采用完全硬件实施例、完全软件实施例、或结合软件和硬件方面的实施例的形式。而且，本发明可采用在一个或多个其中包含有计算机可用程序代码的计算机可用存储介质(包括但不限于磁盘存储器、CD-ROM、光学存储器等)上实施的计算机程序产品的形式。
本发明是参照本发明实施例的方法、设备(系统)、和计算机程序产品的流程图和/或方框图来描述的。应理解可由计算机程序指令实现流程图和/或方框图中的每一流程和/或方框、以及流程图和/或方框图中的流程和/或方框的结合。可提供这些计算机程序指令到通用计算机、专用计算机、嵌入式处理机或其他可编程数据处理设备的处理器以产生一个机器，使得通过计算机或其他可编程数据处理设备的处理器执行的指令产生用于实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能的装置。
这些计算机程序指令也可存储在能引导计算机或其他可编程数据处理设备以特定方式工作的计算机可读存储器中，使得存储在该计算机可读存储器中 的指令产生包括指令装置的制造品，该指令装置实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能。
这些计算机程序指令也可装载到计算机或其他可编程数据处理设备上，使得在计算机或其他可编程设备上执行一系列操作步骤以产生计算机实现的处理，从而在计算机或其他可编程设备上执行的指令提供用于实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能的步骤。
在一个典型的配置中，计算设备包括一个或多个处理器(CPU)、输入/输出接口、网络接口和内存。
存储器可能包括计算机可读介质中的非永久性存储器，随机存取存储器(RAM)和/或非易失性内存等形式，如只读存储器(ROM)或闪存(flash RAM)。存储器是计算机可读介质的示例。
计算机可读介质包括永久性和非永久性、可移动和非可移动媒体可以由任何方法或技术来实现信息存储。信息可以是计算机可读指令、数据结构、程序的模块或其他数据。计算机的存储介质的例子包括，但不限于相变内存(PRAM)、静态随机存取存储器(SRAM)、动态随机存取存储器(DRAM)、其他类型的随机存取存储器(RAM)、只读存储器(ROM)、电可擦除可编程只读存储器(EEPROM)、快闪记忆体或其他内存技术、只读光盘只读存储器(CD-ROM)、数字多功能光盘(DVD)或其他光学存储、磁盒式磁带，磁带磁盘存储或其他磁性存储设备或任何其他非传输介质，可用于存储可以被计算设备访问的信息。按照本文中的界定，计算机可读介质不包括暂存电脑可读媒体(transitory media)，如调制的数据信号和载波。
还需要说明的是，术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含，从而使得包括一系列要素的过程、方法、商品或者设备不仅包括那些要素，而且还包括没有明确列出的其他要素，或者是还包括为这种过程、方法、商品或者设备所固有的要素。在没有更多限制的情况下，由语句“包括一个……”限定的要素，并不排除在包括要素的过程、方法、商品或者设备中还存在另外的相同要素。
本领域技术人员应明白，本发明的实施例可提供为方法、系统或计算机程 序产品。因此，本发明可采用完全硬件实施例、完全软件实施例或结合软件和硬件方面的实施例的形式。而且，本发明可采用在一个或多个其中包含有计算机可用程序代码的计算机可用存储介质(包括但不限于磁盘存储器、CD-ROM、光学存储器等)上实施的计算机程序产品的形式。
以上仅为本发明的实施例而已，并不用于限制本发明。对于本领域技术人员来说，本发明可以有各种更改和变化。凡在本发明的精神和原理之内所作的任何修改、等同替换、改进等，均应包含在本发明的权利要求范围之内。

Claims (12)

  1. 一种针对补液的生理体征监测方法，其特征在于，包括：
    获取监测对象补液情况下中心静脉压监测数据；
    根据所述中心静脉压监测数据，生成中心静脉压趋势信息；
    在主监测界面内显示补液情况专用工具界面；
    在所述补液情况专用工具界面内显示所述中心静脉压趋势信息；
    基于获取到的新的中心静脉压监测数据，刷新显示在所述补液情况专用工具界面内的中心静脉压趋势信息。
  2. 根据权利要求1所述的方法，其特征在于，所述中心静脉压趋势信息包括中心静脉压趋势表、中心静脉压趋势图中的至少一种。
  3. 根据权利要求2所述的方法，其特征在于，在所述补液情况专用工具界面内至少显示所述中心静脉压趋势图，所述方法还包括：
    在所述中心静脉压趋势图中生成并显示所述监测对象对应的补液基线。
  4. 根据权利要求3所述的方法，其特征在于，在所述中心静脉压趋势图中生成并显示所述监测对象对应的补液基线之前，所述方法还包括：
    基于打开所述补液情况专用工具界面时中心静脉压的测量值来确定所述补液基线对应的数值；
    或者，基于用户输入的配置信息确定所述补液基线对应的数值。
  5. 根据权利要求3所述的方法，其特征在于，所述方法还包括：
    在所述中心静脉压趋势图中生成并显示第一标识线和/或第二标识线，所述第一标识线、所述第二标识线与所述补液基线具有关联关系，且所述第一标识线对应的数值小于所述第二标识线对应的数值，所述补液基线对应的数值小于所述第一标识线对应的数值。
  6. 根据权利要求5所述的方法，其特征在于，所述方法还包括：确定到所述监测对象的中心静脉压的测量值超过所述第一标识线对应的数值时，生成第一提示信息；和/或，确定到所述监测对象的中心静脉压的测量值超过所述第二标识线对应的数值时，生成区别于第一提示信息的第二提示信息。
  7. 根据权利要求6所述的方法，其特征在于，所述第一提示信息包括表示需要暂停对所述监测对象进行补液的通知信息，所述第二提示信息包括表示 需要终止对所述监测对象进行补液的通知信息。
  8. 根据权利要求5所述的方法，其特征在于，所述第一标识线对应的数值和所述第二标识线对应的数值基于用户输入的配置信息确定。
  9. 根据权利要求1所述的方法，其特征在于，还包括：
    获取所述监测对象与补液情况关联的生理体征监测数据，所述与补液情况关联的生理体征至少包括心率、动脉压、无创血压、血氧以及血流灌注指数中的一种；
    基于所述与补液情况关联的生理体征监测数据生成与补液情况关联的生理体征对应的波形图和/或数值信息；
    在所述补液情况专用工具界面显示所述与补液情况关联的生理体征对应的波形图和/或数值信息；
    基于获取到的新的与补液情况关联的生理体征监测数据，刷新显示在所述补液情况专用工具界面内与补液情况关联的生理体征对应的波形图和/或数值信息。
  10. 根据权利要求9所述的方法，其特征在于，当所述补液情况专用工具界面至少显示中心静脉压趋势图和/或所述与补液情况关联的生理体征对应的波形图时，所述方法还包括：
    响应用户在所述补液情况专用工具界面中的操作，在所述趋势图和/或波形图中生成并显示时间线；
    显示所述中心静脉压和/或所述与补液情况关联的生理体征在所述时间线对应的时间点的测量值。
  11. 一种监护设备，其特征在于，包括：
    显示器，所述显示器配置为显示信息；
    存储器，所述存储器存储有程序指令；
    处理器，所述处理器执行所述程序指令实现如权利要求1-10任意一项所述的方法。
  12. 一种计算机可读存储介质，包括指令，当其在计算机上运行时，使得计算机执行如权利要求1-10中任一项所述的方法。
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