WO2020108629A8 - 一种多肽rdp1及其提纯方法与应用 - Google Patents

一种多肽rdp1及其提纯方法与应用 Download PDF

Info

Publication number
WO2020108629A8
WO2020108629A8 PCT/CN2019/122077 CN2019122077W WO2020108629A8 WO 2020108629 A8 WO2020108629 A8 WO 2020108629A8 CN 2019122077 W CN2019122077 W CN 2019122077W WO 2020108629 A8 WO2020108629 A8 WO 2020108629A8
Authority
WO
WIPO (PCT)
Prior art keywords
rdp1
polypeptide
purification method
hyperuricaemia
present
Prior art date
Application number
PCT/CN2019/122077
Other languages
English (en)
French (fr)
Other versions
WO2020108629A1 (zh
Inventor
杨新旺
孙俊
孟步亮
刘乃心
王滢
Original Assignee
西安棣加生物科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 西安棣加生物科技有限公司 filed Critical 西安棣加生物科技有限公司
Publication of WO2020108629A1 publication Critical patent/WO2020108629A1/zh
Publication of WO2020108629A8 publication Critical patent/WO2020108629A8/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

本发明公开了一种抗高尿酸血症多肽RDP1,所述多肽RDP1包含的氨基酸序列如SEQ No.1所示。本发明还公开了所述多肽RDP1的提纯方法和应用。本发明所述抗高尿酸血症肽RDP1可减轻高尿酸血症,缓解肾损伤,具有广阔的应用前景。
PCT/CN2019/122077 2018-11-30 2019-11-29 一种多肽rdp1及其提纯方法与应用 WO2020108629A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201811456981.5 2018-11-30
CN201811456981.5A CN109369783B (zh) 2018-11-30 2018-11-30 一种多肽rdp1及其提纯方法与应用

Publications (2)

Publication Number Publication Date
WO2020108629A1 WO2020108629A1 (zh) 2020-06-04
WO2020108629A8 true WO2020108629A8 (zh) 2020-07-30

Family

ID=65376214

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2019/122077 WO2020108629A1 (zh) 2018-11-30 2019-11-29 一种多肽rdp1及其提纯方法与应用

Country Status (2)

Country Link
CN (1) CN109369783B (zh)
WO (1) WO2020108629A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109369783B (zh) * 2018-11-30 2021-09-10 昆明医科大学 一种多肽rdp1及其提纯方法与应用
CN111533783B (zh) * 2020-05-21 2022-03-18 昆明医科大学 一种抗痛风活性多肽rdp2及其制备方法与应用
CN111606973B (zh) * 2020-05-21 2022-03-18 昆明医科大学 一种抗痛风活性多肽rdp3及其制备方法与应用
CN118126130B (zh) * 2024-05-06 2024-06-28 中国海洋大学 小分子肽及其在制备黄嘌呤氧化酶抑制剂中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214786B2 (en) * 2000-12-14 2007-05-08 Kovalic David K Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
SG183721A1 (en) * 2007-11-27 2012-09-27 Ardea Biosciences Inc Novel compounds and compositions and methods of use
CN109369783B (zh) * 2018-11-30 2021-09-10 昆明医科大学 一种多肽rdp1及其提纯方法与应用

Also Published As

Publication number Publication date
CN109369783A (zh) 2019-02-22
CN109369783B (zh) 2021-09-10
WO2020108629A1 (zh) 2020-06-04

Similar Documents

Publication Publication Date Title
WO2020108629A8 (zh) 一种多肽rdp1及其提纯方法与应用
MX2021010559A (es) Polipéptidos efectores de crispr-cas y métodos de uso de estos.
WO2018067217A3 (en) COMPOSITIONS COMPRISING SHORT PEPTIDES DERIVED FROM PEDF AND USES THEREOF
AU2017248121A1 (en) T cell receptors
AU2017263237A1 (en) GDF15 fusion proteins and uses thereof
MX2020010806A (es) Peptidos anti-inflamatorios y usos de los mismos.
WO2017075505A3 (en) Novel polypeptides with improved proteolytic stability, and methods of preparing and using same
EP4249097A3 (en) Fc binding proteins with cysteine in the c-terminal helical region
MX2019006515A (es) Composiciones que comprenden peptido wkdeagkplvk.
EP4276463A3 (en) Peptides
MX2021011726A (es) Escindasas modificadas, usos de las mismas y kits relacionados.
MX2021001129A (es) Metodo de purificacion de antigenos.
NZ781143A (en) Anti-vegf protein compositions and methods for producing the same
MX2023001595A (es) Proteinas de fusion que comprenden proteinas de leche y composiciones de las mismas.
SG11202000115SA (en) Novel therapeutic enzyme fusion protein and use thereof
MX2020010716A (es) Metodo para escindir de la fase solida peptidos unidos a una fase solida.
WO2023102329A3 (en) Effector proteins and uses thereof
EP4041873A4 (en) PROTEINS CONTAINING MULTIPLE DIFFERENT NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING SUCH PROTEINS
WO2019094938A3 (en) Methods and compositions for the treatment of wounds
WO2020113141A3 (en) Cd86 variant immunomodulatory proteins and uses thereof
GB0107319D0 (en) Bacteriophage-mediated immunisation
PH12021551055A1 (en) Klk5 inhibitory peptide
PH12018500468A1 (en) Fusion protein
MX2018003445A (es) Expresion de proteinas que contienen fc.
EP3666893A8 (en) D type amino acid dehydrogenase

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19888704

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 19888704

Country of ref document: EP

Kind code of ref document: A1

122 Ep: pct application non-entry in european phase

Ref document number: 19888704

Country of ref document: EP

Kind code of ref document: A1

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC (EPO FORM 1205 DATED 27.06.2022)