WO2020107227A1 - Composition de médecine chinoise traditionnelle, et son procédé de préparation et utilisation associée - Google Patents
Composition de médecine chinoise traditionnelle, et son procédé de préparation et utilisation associée Download PDFInfo
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- WO2020107227A1 WO2020107227A1 PCT/CN2018/117739 CN2018117739W WO2020107227A1 WO 2020107227 A1 WO2020107227 A1 WO 2020107227A1 CN 2018117739 W CN2018117739 W CN 2018117739W WO 2020107227 A1 WO2020107227 A1 WO 2020107227A1
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- chinese medicine
- traditional chinese
- medicine composition
- ginseng
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Definitions
- the invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, its preparation method and application.
- the technical problem to be solved by the present invention is to treat various diseases described in the background art.
- the present invention discloses a traditional Chinese medicine composition, which is prepared by the following proportion of traditional Chinese medicine raw materials in terms of parts by weight: 40-240 parts of gypsum, 30-120 parts of Zhimu, 5-45 parts of ginseng, 15-60 copies of licorice.
- the invention also discloses a method for preparing a traditional Chinese medicine composition, which comprises the following steps:
- the mass ratio of the raw material of traditional Chinese medicine to water is 1: 4-6, and the soaking time is 20-40 min.
- step S3 first heat to boiling, and then continue to cook for 60-90 min at 100-115°C.
- the final amount of medicinal juice obtained is 1/2-7/10 of the amount of added water.
- the invention also provides the application of a traditional Chinese medicine composition in the preparation of drugs for eliminating troubles, nourishing yin and nourishing yin.
- the traditional Chinese medicine composition disclosed by the invention has the functions of eliminating troubles and nourishing and nourishing yin and nourishing yin.
- the above-mentioned traditional Chinese medicine raw materials cooperate with each other according to the compatibility relationship of "Jun, Chen, Zuo, Shi", and work synergistically to prevent the yang caused by the warm evil from converging and releasing, warming the body, sweating, and thirst, And epilepsy, cough, abdominal pain, constipation, jaundice, or exogenous warmth that does not hate wind and cold caused by the entrapment of water and heat caused by warming and losing heat, including some diabetes in modern medicine and seeing fever, sweating, thirst, or gout syndrome Symptoms such as fever, sweating and thirst have obvious healing effect or relief effect. Suitable for clinical application.
- FIG. 1 is a flowchart of a method for preparing a traditional Chinese medicine composition provided by an embodiment of the present invention.
- the embodiment of the present invention provides a traditional Chinese medicine composition, in which gypsum, timothrum, ginseng and licorice root are selected as raw materials of traditional Chinese medicine.
- gypsum has the effect of clearing away heat and purging fire, eliminating anxiety and quenching thirst.
- Zhimu has the effects of clearing heat and purging fire, nourishing yin and moisturizing, etc., and can treat fever and thirst, lung heat and dry cough, bone steaming hot flashes, internal heat and thirst, intestinal dry constipation.
- Ginseng has the functions of nourishing vital energy, replenishing the veins, solidifying the spleen, nourishing the spleen and lungs, regenerating the body and soothing the nerves.
- Roasted licorice has the effect of nourishing qi and nourishing yin, and Tongyang Fumai.
- the above-mentioned traditional Chinese medicine raw materials cooperate with each other according to the compatibility relationship of "Jun, Chen, Zuo, Shi", and can synergistically be used to treat dryness and dryness caused by heat injury fluid.
- japonica rice also has the effect of removing thirst and replenishing fluid, however The efficacy of Ginseng Bujin Liquid is far greater than that of japonica rice, and the use of ginseng is more symptomatic than japonica rice. Therefore, no japonica rice is added to the traditional Chinese medicine composition provided by the present invention.
- This embodiment provides a Chinese medicine composition, which includes 40 g of gypsum, 30 g of Anophora, 5 g of ginseng, and 15 g of licorice root.
- This embodiment also provides a method for preparing a traditional Chinese medicine composition, which includes the following steps:
- the above-mentioned traditional Chinese medicine composition can be used for the preparation of medicines for removing anxiety, nourishing and nourishing yin.
- the traditional Chinese medicine composition includes 240 g of gypsum, 90 g of Zhimu, 45 g of ginseng, and 30 g of licorice root.
- This embodiment also provides a method for preparing a traditional Chinese medicine composition, which includes the following steps:
- the above-mentioned traditional Chinese medicine composition can be used for the preparation of medicines for removing anxiety, nourishing and nourishing yin.
- This embodiment provides a traditional Chinese medicine composition, which includes 100 g of gypsum, 120 g of Anophora, 35 g of ginseng, and 60 g of licorice root.
- This embodiment also provides a method for preparing a traditional Chinese medicine composition, which includes the following steps:
- the above-mentioned traditional Chinese medicine composition can be used for the preparation of medicines for removing anxiety, nourishing and nourishing yin.
- This embodiment provides a traditional Chinese medicine composition, which includes 150 g of gypsum, 80 g of timothrum, 32 g of ginseng, and 35 g of licorice root.
- This embodiment also provides a method for preparing a traditional Chinese medicine composition, which includes the following steps:
- the above-mentioned traditional Chinese medicine composition can be used for the preparation of medicines for removing anxiety, nourishing and nourishing yin.
- the present invention also provides the traditional Chinese medicine compositions of Examples 5-10.
- the traditional Chinese medicine composition can be used for the preparation of drugs for relieving troubles and nourishing yin and nourishing yin and nourishing jin.
- Table 1 can be prepared by the preparation methods described in Examples 1-4,
- Gypsum (g) Mother (g) Ginseng (g) Roasted Licorice (g) 5 235 110 20 19 6 52 95 38 29 7 130 35 43 58 8 200 90 13 43 9 185 58 29 46 10 86 69 9 25
- Table 1 The Chinese medicine composition provided by Examples 5-10
- Subjects A total of 1058 patients, including 698 male patients and 360 female patients, with an age distribution of 45-80 years old. All patients had thermal dysentery or even bloody dysentery caused by the fire poisoning, and the clinical performance was not bad. Cold is against evil heat, sweating spontaneously, sweating more than sweating, dry mouth, tongue burning, polydipsia, drinking, not thirsty, pulse like Hongda.
- Treatment Take the Chinese medicine composition juice in the scheme of Example 1 of the present invention, take it three times in the morning, middle and evening, each time taking 150-350ml, warmly take Qihe, and observe the clinical efficacy.
- Criteria for curative effect 1) cured, symptoms and signs completely disappeared; 2) markedly effective, most symptoms and signs disappeared after treatment; 3) ineffective, symptoms and signs have not been relieved or even aggravated.
- the Chinese medicine composition in the present scheme under the mutual cooperation and synergistic effect of each specific compatible Chinese herbal medicine component, has the effect of curing and alleviating the related diseases caused by the evil of warmth,
- the obvious curative effect of nourishing yin and nourishing jin is suitable for clinical application.
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Composition de médecine chinoise traditionnelle, et son procédé de préparation et utilisation associée. La composition de médecine chinoise traditionnelle est préparée à partir des matières premières de médecine chinoise traditionnelle suivantes en parts : 40 à 240 parts de Gypsum fibrosum, de 30 à 120 parts d'Anemarrhenae rhizome, de 5 à 45 parts de Ginseng radix et rhizoma, et de 15 à 60 parts de Glycyrrhizae radix et rhizoma praeparata cum melle. La composition de médecine chinoise traditionnelle a pour effets de soulager l'agitation et de réalimenter en fluide corporel, et de nourrir le Yin et de réalimenter en fluide corporel ; et présente des effets thérapeutiques ou d'atténuation sur des patients atteints d'épilepsie, de toux, de douleur abdominale et de constipation, de jaunisse ou de maladies fébriles épidémiques provoquées par la chaleur et l'épuisement du fluide accompagné de la chaleur de l'eau, et sur des symptômes de diabètes accompagnés de fièvre, de transpiration et de soif, ou de symptômes de la goutte accompagnés de fièvre, de transpiration et de soif.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
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CN201880028269.7A CN111491650A (zh) | 2018-11-27 | 2018-11-27 | 一种中药组合物及其制备方法以及应用 |
PCT/CN2018/117739 WO2020107227A1 (fr) | 2018-11-27 | 2018-11-27 | Composition de médecine chinoise traditionnelle, et son procédé de préparation et utilisation associée |
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PCT/CN2018/117739 WO2020107227A1 (fr) | 2018-11-27 | 2018-11-27 | Composition de médecine chinoise traditionnelle, et son procédé de préparation et utilisation associée |
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WO2020107227A1 true WO2020107227A1 (fr) | 2020-06-04 |
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PCT/CN2018/117739 WO2020107227A1 (fr) | 2018-11-27 | 2018-11-27 | Composition de médecine chinoise traditionnelle, et son procédé de préparation et utilisation associée |
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Citations (1)
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CN101062306A (zh) * | 2007-05-23 | 2007-10-31 | 陈江 | 白虎人参汤 |
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- 2018-11-27 WO PCT/CN2018/117739 patent/WO2020107227A1/fr active Application Filing
- 2018-11-27 CN CN201880028269.7A patent/CN111491650A/zh active Pending
Patent Citations (1)
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CN101062306A (zh) * | 2007-05-23 | 2007-10-31 | 陈江 | 白虎人参汤 |
Non-Patent Citations (2)
Title |
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GUAN TONG: "Clinical observation on 33 cases of ankylosing spondylitis treated by syndrome differentiation and typing", vol. 17, no. 03, 1 August 3106 (3106-08-01) * |
WU CHUNLEI: "37 cases of ankylosing spondylitis treated by CT-guided sacroiliac joint injection combined with TCM syndrome differentiation", vol. 35, no. 2, 1 August 3005 (3005-08-01) * |
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