WO2019223841A1 - Dosiervorrichtung - Google Patents
Dosiervorrichtung Download PDFInfo
- Publication number
- WO2019223841A1 WO2019223841A1 PCT/DE2019/200046 DE2019200046W WO2019223841A1 WO 2019223841 A1 WO2019223841 A1 WO 2019223841A1 DE 2019200046 W DE2019200046 W DE 2019200046W WO 2019223841 A1 WO2019223841 A1 WO 2019223841A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- liquid
- drinking
- metering device
- control device
- drinking vessel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/0015—Devices specially adapted for taking medicines
- A61J7/0046—Cups, bottles or bags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0418—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
- A61J7/0445—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system for preventing drug dispensing during a predetermined time period
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/065—Rigid ampoules, e.g. glass ampoules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1437—Locking means requiring key or combination to open the container
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/70—Device provided with specific sensor or indicating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/70—Device provided with specific sensor or indicating means
- A61J2200/76—Device provided with specific sensor or indicating means for fluid level
Definitions
- the invention relates to a metering device and a drinking bottle with such a metering device.
- Bottles are known in various designs. After it has been proven that a regular fluid intake in humans is necessary for the health, drinking bottles are widely used. Bottles can therefore serve for the daily supply of liquids.
- liquid is an active ingredient or the liquid such
- Levodopa (C9H11NO4), also known as L-dopa, is the abbreviation for L-3,4-dihydroxyphenylalanine, a non-proteinogenic a-amino acid found in the body of tyrosine with the help of the enzyme
- Tyrosine hydroxylase is formed. It occurs as a white, crystalline powder that is sparingly soluble in water.
- Levodopa can be converted into the active neurotransmitter dopamine in the central nervous system by decarboxylation. Levodopa is used to treat Parkinson's disease. This is intended to increase the dopamine concentration in the basal cells of the cerebrum.
- Parkinson's disease is one of the most common chronic neurological diseases, during which it usually comes after a few years to effect fluctuations (so-called motor and non-motor Wirkflaktuationen).
- PEG with Jet-PEG enteric invasive gastric tube
- a subcutaneously applied soluble dopamine agonist therapy eg APO-Go®
- TIIS deep-throat stimulation
- the problems with these therapies are in addition to the considerable effort and the z.T. very high
- the object of the present invention is therefore to provide a metering device with the aid of which precisely defined amounts of liquid can be removed from a drinking vessel at specific times.
- the metering device should be able to form an easily manageable unit together with the drinking vessel, which in the case of more frequent, e.g. per hourly intake can make this possible in a simple way outside the home (on the way).
- the metering device generally serves to regulate the delivery of the liquid from the drinking vessel. In this case, various forms of metering device are possible. Ultimately, it depends on which liquids are to be dispensed. Some embodiments of the metering device will be described below.
- the metering device according to the invention is particularly suitable for the dosage of
- Drug fluids in particular for the dosed and timed intake of a drug suspension, such as a levodopa suspension for the high-frequency treatment of idiopathic Parkinson's disease.
- a liquid is therefore also understood to mean a suspension, ie. H. a heterogeneous mixture of a liquid and finely dispersed solids.
- the liquid medium may be a heterogeneous substance mixture used in medicine.
- the drinking vessel for example, with a commercial and approved levodopa / carbidopa suspension in a fixed
- a defined maximum dose eg. 1000 mg / d.
- a maximum daily dose in mg can thus be selected. If this maximum dose is reached, then no more liquid can be dispensed to avoid overdose. Then it may be necessary to switch to other therapeutic procedures.
- dopaminergic solutions may also be used (eg, soluble
- the metering device has a control device which detects the delivery of the liquid via sensors (eg flow or weight sensors) and can pass on corresponding signals to a display and / or evaluation unit.
- the delivered amount of liquid can thus be registered and, for example, form the basis for the delivery of a next dose.
- the controller may control the delivery of the liquid. It converts input signals into drive movements in the dosing device. For example, a pump or a valve can be controlled, whereby a defined amount of liquid released or the liquid flow is interrupted.
- the control device is, in particular, a programmable logic control device, i. H. a microcontroller with memories for the control program and control parameters.
- control device can also be used to create a wireless connection, for example to smartphones or tablet devices, so that programming of the system or queries of therapy protocols via smartphone apps (for example, by the doctor, possibly also with the help of telemedical methods) are possible.
- smartphones or tablet devices so that programming of the system or queries of therapy protocols via smartphone apps (for example, by the doctor, possibly also with the help of telemedical methods) are possible.
- smartphone apps for example, by the doctor, possibly also with the help of telemedical methods
- patients can also be reminded about the timely intake of their medication via such modules and the correct intake can be recorded.
- the drinking vessel may be made of glass, plastic or other materials. Depending on
- the drinking vessel may also be provided with a light protection for the liquid.
- a lightweight plastic bottle is inexpensive to produce and easy to handle.
- the size of the drinking vessel depends on the respective application. 200 and 500 ml bottles are preferred.
- the delivery of the liquid is time-dependent via the control device.
- the controller may direct signals to a pump such that the pump may deliver and deliver a defined volume of fluid for delivery to a patient.
- a time-dependent control can also mean that predetermined time intervals between two drug withdrawals are set, so that a drug withdrawal is prevented in shorter time intervals.
- control device is designed to generate a signal visually and / or acoustically detectable for the user of the drinking vessel.
- a signal can emanate from the metering device or the drinking vessel.
- LEDs in different colors may be lit and beeps may sound indicating to the user that liquid intake is required or sufficient
- the control device can also be designed to generate an electronic signal for
- the metering device to a
- Such a storage chamber can be located, for example, in the closure device of the drinking vessel.
- the storage chamber is filled after programming each with a defined amount of the liquid medium, for example via an electrically operated pump. The medium can then be removed from the storage chamber.
- sensors eg flow or weight sensors
- the sensors give their signals to the control device, which detects the delivery of the liquid and can pass on appropriate signals to a display and / or evaluation. If the amount of liquid dispensed is registered, more can be added
- Program steps are initiated, for example, the person may be asked to take more liquid or the liquid delivery is interrupted by a valve and it begins a new time cycle to deliver a next dose.
- control device is assigned a control panel via which volume and time parameters for the medium to be delivered can be set.
- This control panel can be integrated in the closure device, whereby the metering device is overall easy to handle and operate. But it can also be attached to the outside of the drinking vessel. Through the control panel, all
- Adjustment parameters including the drug concentration, be adjustable and / or retrievable.
- the present invention also relates to a drinking bottle with a metering device.
- the metering device is in the closing device of the bottle.
- the closing device can be combined with the metering device as a separate unit from a drinking bottle and, for example, combined with other drinking vessels.
- the closure device is screwed sealingly on the drinking vessel. But there are also other connections possible such as a bayonet lock.
- the drinking bottle may have a stirrer in case of using
- the agitator can be operated by an electric motor and by the
- Control device possibly be controlled immediately before a liquid removal.
- the stirring motor of the agitator is preferably integrated in the closing device, so that the stirring shaft projects with the stirring elements into the drinking vessel. Such a construction allows the use of the bottle at any location.
- Fig. 2 is a closing device in a side view
- Fig. 3 is a closing device with stirrer and
- Fig. 4 is a closing device with control panel in a plan view.
- the drinking bottle 8 according to FIG. 1 has a drinking vessel 2, which forms the bottle body.
- the drinking vessel 2 has a cylindrical shape with a bottleneck 14 to which an eyelet 15 is attached for attachment of a carrying strap, not shown.
- the drinking vessel 2 is made of plastic, z. B. polyethylene terephthalate (PET). As described above, but also other materials come into consideration, depending on whether it is the drinking vessel 2 to a on or Reusable drinking vessel is or whether the drinking vessel 2 should be compressible.
- PET polyethylene terephthalate
- the drinking vessel 2 is formed single-walled. But it can also be double-walled to the
- the wall 16 of the drinking vessel 2 is here provided with a light protection coating 17. It has an over the length of the drinking vessel 2 extending viewing window 11 with a display device in the form of a scale 12 in order to control the level of the drinking vessel 2 can.
- the closing device 9 is schraubelementformig and closes the
- the drinking spout 19 is provided with a drinking spout 19 through which the liquid 3 can be dispensed.
- the drinking spout 18 may additionally be provided with a mouthpiece.
- control device 4 In the interior of the closure device 9 are the control device 4 and the storage chamber 5. In addition, the entire sensor system, lines for the liquid 3, valves and devices for power supply are arranged in the closing device 9.
- a closing device 9 is shown in a side view.
- Control device 4 controllable valve 18 shuts off the line 19 for the liquid 3.
- a sensor 6 is provided in the form of a flow sensor, which is also connected to the control device 4.
- FIG 3 shows a closing device 9 with agitator 10.
- the agitator 10 is driven by an electric motor 20 and is formed with a stirring shaft 21 on which stirring elements 22 are arranged.
- the agitator 10 may also be connected to the control device 4.
- the closure device 9 shows the control panel 7, which has a display 23 for displaying the relevant setting parameters such as dosing volume, dosing times and the like. having.
- controls z. B. in the form of buttons 24, 25 and optical
- a smartphone app or the control panel 7 the volume and time parameters for the liquid 3 to be dispensed are then set in accordance with the medical prescription. So the
- a lock code can be set up here which releases the programming system after correct entry for changes. For example, the following parameters are entered:
- the patient Via the control panel 7 of the dosing device 1 and / or a smartphone app, the patient is reminded to take the drug. At the same time, a message can be sent to the attending physician or nursing staff, for example in a nursing facility.
- the control device 4 of the metering device 1 then releases the set volume of the liquid 3, the levodopa suspension, at the predetermined time. D. h., The set volume is delivered via the metering device 1 and is available to the patient. If the medication provided is not taken, another message will be sent to the doctor or nurse.
- the patient may make his own entry and retrieve the demand dose. Since all medication can be detected in this way, a therapy protocol can be easily created and evaluations can be made. LIST OF REFERENCE NUMBERS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR112020024097-4A BR112020024097A2 (pt) | 2018-05-25 | 2019-05-24 | dispositivo de dosagem |
US17/057,789 US20210196573A1 (en) | 2018-05-25 | 2019-05-24 | Metering device |
DE112019002661.5T DE112019002661A5 (de) | 2018-05-25 | 2019-05-24 | Dosiervorrichtung |
EP19732251.4A EP3801438A1 (de) | 2018-05-25 | 2019-05-24 | Dosiervorrichtung |
CN201980045991.6A CN112384186A (zh) | 2018-05-25 | 2019-05-24 | 计量装置 |
CONC2020/0014494A CO2020014494A2 (es) | 2018-05-25 | 2020-11-23 | Dispositivo de medicion |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102018112608.5 | 2018-05-25 | ||
DE102018112608.5A DE102018112608A1 (de) | 2018-05-25 | 2018-05-25 | Dosiervorrichtung |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2019223841A1 true WO2019223841A1 (de) | 2019-11-28 |
Family
ID=66999540
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE2019/200046 WO2019223841A1 (de) | 2018-05-25 | 2019-05-24 | Dosiervorrichtung |
Country Status (8)
Country | Link |
---|---|
US (1) | US20210196573A1 (de) |
EP (1) | EP3801438A1 (de) |
CN (1) | CN112384186A (de) |
BR (1) | BR112020024097A2 (de) |
CL (1) | CL2020003036A1 (de) |
CO (1) | CO2020014494A2 (de) |
DE (2) | DE102018112608A1 (de) |
WO (1) | WO2019223841A1 (de) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10138063A1 (de) * | 2001-08-03 | 2003-02-27 | Helmut Bucksch | Trinkgefäß mit einer Vorrichtung zur Anzeige der Trinkmenge |
EP1719984A1 (de) * | 2005-05-03 | 2006-11-08 | Districare OHG | Vorrichtung zur Kontrolle der Flüssigkeitsentnahme aus einem Trinkgefäß |
US20100270257A1 (en) * | 2005-07-13 | 2010-10-28 | Vitality, Inc. | Medicine Bottle Cap With Electronic Embedded Curved Display |
DE102010041112A1 (de) * | 2010-09-21 | 2012-03-22 | Robert Bosch Gmbh | Durchflussmessgerät für einen Flüssigkeitsbehälter und Verfahren zur Hydrationsüberwachung eines Patienten |
DE202017003569U1 (de) | 2016-08-26 | 2017-08-16 | BSN BürgerServiceNetz UG (haftungsbeschränkt) | Anordnung zur kontrollierten zeitgerechten Flüssigkeitsaufnahme |
DE102010049727B4 (de) | 2010-10-30 | 2018-04-05 | Silag Handel Ag | Einstellbarer Trinkflaschenverschluß mit Trinkhalmfunktion |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5300042A (en) * | 1992-03-02 | 1994-04-05 | Kossoff-Sukel, Inc. | Medication dispensing apparatus |
DE4411021C1 (de) * | 1994-03-30 | 1995-07-20 | Henkel Kgaa | Zweikammerdosierer mit integriertem, abdichtendem Dosiermengenregulator und Verfahren zum Dosieren von Flüssigkeiten |
US6249717B1 (en) * | 1996-11-08 | 2001-06-19 | Sangstat Medical Corporation | Liquid medication dispenser apparatus |
US6252494B1 (en) * | 2000-01-28 | 2001-06-26 | Michael D. Howell | Timed dispenser for programmed fluid consumption |
CA2568141A1 (en) * | 2006-11-06 | 2008-05-06 | Atabakhsh Rahim | Unit dose liquid dispenser |
US8236253B2 (en) * | 2007-04-30 | 2012-08-07 | Midmark Corporation | Portable sterilizing apparatus for surgical and dental instruments |
US8224481B2 (en) * | 2009-01-19 | 2012-07-17 | Access Business Group International Llc | Method and apparatus for dispensing fluid compositions |
JP5614695B2 (ja) * | 2010-03-29 | 2014-10-29 | エチメディックス エスエー | 安全な液状薬剤ディスペンサおよび液状医薬品の投与方法 |
US9563600B2 (en) * | 2012-08-23 | 2017-02-07 | Leigh M. Rothschild | System and method for monitoring and dispensing doses of medication |
US9301648B2 (en) * | 2013-02-21 | 2016-04-05 | Headquarters, Inc. | Drink mixer bottle and agitator |
-
2018
- 2018-05-25 DE DE102018112608.5A patent/DE102018112608A1/de not_active Withdrawn
-
2019
- 2019-05-24 CN CN201980045991.6A patent/CN112384186A/zh active Pending
- 2019-05-24 US US17/057,789 patent/US20210196573A1/en active Pending
- 2019-05-24 DE DE112019002661.5T patent/DE112019002661A5/de active Pending
- 2019-05-24 EP EP19732251.4A patent/EP3801438A1/de active Pending
- 2019-05-24 WO PCT/DE2019/200046 patent/WO2019223841A1/de unknown
- 2019-05-24 BR BR112020024097-4A patent/BR112020024097A2/pt not_active Application Discontinuation
-
2020
- 2020-11-23 CO CONC2020/0014494A patent/CO2020014494A2/es unknown
- 2020-11-24 CL CL2020003036A patent/CL2020003036A1/es unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10138063A1 (de) * | 2001-08-03 | 2003-02-27 | Helmut Bucksch | Trinkgefäß mit einer Vorrichtung zur Anzeige der Trinkmenge |
EP1719984A1 (de) * | 2005-05-03 | 2006-11-08 | Districare OHG | Vorrichtung zur Kontrolle der Flüssigkeitsentnahme aus einem Trinkgefäß |
US20100270257A1 (en) * | 2005-07-13 | 2010-10-28 | Vitality, Inc. | Medicine Bottle Cap With Electronic Embedded Curved Display |
DE102010041112A1 (de) * | 2010-09-21 | 2012-03-22 | Robert Bosch Gmbh | Durchflussmessgerät für einen Flüssigkeitsbehälter und Verfahren zur Hydrationsüberwachung eines Patienten |
DE102010049727B4 (de) | 2010-10-30 | 2018-04-05 | Silag Handel Ag | Einstellbarer Trinkflaschenverschluß mit Trinkhalmfunktion |
DE202017003569U1 (de) | 2016-08-26 | 2017-08-16 | BSN BürgerServiceNetz UG (haftungsbeschränkt) | Anordnung zur kontrollierten zeitgerechten Flüssigkeitsaufnahme |
Also Published As
Publication number | Publication date |
---|---|
CL2020003036A1 (es) | 2021-06-11 |
CN112384186A (zh) | 2021-02-19 |
DE112019002661A5 (de) | 2021-03-11 |
BR112020024097A2 (pt) | 2021-02-17 |
CO2020014494A2 (es) | 2020-12-10 |
DE102018112608A1 (de) | 2019-11-28 |
EP3801438A1 (de) | 2021-04-14 |
US20210196573A1 (en) | 2021-07-01 |
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