WO2019196767A1 - 一种图像引导放射治疗设备 - Google Patents

一种图像引导放射治疗设备 Download PDF

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WO2019196767A1
WO2019196767A1 PCT/CN2019/081680 CN2019081680W WO2019196767A1 WO 2019196767 A1 WO2019196767 A1 WO 2019196767A1 CN 2019081680 W CN2019081680 W CN 2019081680W WO 2019196767 A1 WO2019196767 A1 WO 2019196767A1
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strip
imaging
annular frame
imager
sources
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PCT/CN2019/081680
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English (en)
French (fr)
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闫浩
刘海峰
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西安大医集团有限公司
深圳市奥沃医学新技术发展有限公司
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Publication of WO2019196767A1 publication Critical patent/WO2019196767A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • A61N5/1065—Beam adjustment
    • A61N5/1067—Beam adjustment in real time, i.e. during treatment

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  • the present disclosure relates to the field of radiation therapy technologies, and in particular, to an image guided radiation therapy device.
  • the Image Guided Radiation Therapy (IGRT) technology can position the patient target area before treatment by the imaging device, and perform real-time localization tracking of the target target area during treatment. It can reduce the probability of damage to normal tissues and key organs around the tumor during the treatment, so as to achieve accurate radiation therapy for the tumor.
  • IGRT Image Guided Radiation Therapy
  • the radiation therapy apparatus includes an annular frame 01 rotatable about a central axis, and a radiation therapy head 02 disposed on the annular frame 01 (eg, Multi-source focused treatment head) and imaging device.
  • the radiation therapy head 02 can emit a treatment beam to perform radiation therapy on the patient's tumor target area (the target area is on the central axis).
  • the imaging device may be composed of an oppositely disposed imaging source 03 and an imager 04, and the imaging device may be disposed at 90 degrees to the radiation therapy head 02 on the annular frame 01, which may generate a cone-shaped imaging beam and may acquire A two-dimensional image of the target area of the tumor.
  • the imaging apparatus can collect only a two-dimensional image of the tumor target area at the position A with respect to the plane of the y-axis and the z-axis at the position shown in FIG.
  • the two-dimensional image cannot reflect the positional shift of the tumor target area in the x-axis direction, for example, cannot reflect the positional shift of the tumor target area from the position A to the position A'. Therefore, the imaging device also needs to be rotated by a certain angle under the driving of the annular frame 01, and a two-dimensional image of the tumor target region is collected at the angle.
  • the image-guided radiotherapy apparatus may reconstruct the acquired plurality of two-dimensional images to obtain a three-dimensional image, and then register the three-dimensional image with the three-dimensional image in the treatment plan to obtain a positional shift of the tumor target area of the patient.
  • the treatment bed can be adjusted according to the positional shift of the tumor target area, so that the treatment beam emitted by the radiation treatment head 02 can hit the tumor target area.
  • the position of the target area of the patient may be The offset occurs again, for example from position A' shown in Figure 1 to a position between positions A and A'.
  • the position of the treatment beam hit by the radiation therapy 02 hair is not the position A' where the current tumor target area is located, and the accuracy of the radiation treatment is low.
  • the present disclosure provides an image-guided radiotherapy apparatus that can track the positional deviation of a tumor target area in real time and guide the radiation treatment head to perform radiation treatment according to the positional deviation, which can solve the radiotherapy precision in the related art. Not a high problem.
  • An embodiment of the present disclosure provides an image-guided radiation therapy apparatus, the apparatus comprising: an annular frame rotatable about a central axis; a radiation therapy head disposed on the annular frame for emitting a treatment beam; An imaging source for emitting an imaging beam, the strip imaging source being disposed in a first direction adjacent to the radiation therapy head; and a strip imager disposed in a second direction on a side of the strip imaging source And for receiving the imaging beam and for converting the imaging beam into a three-dimensional imaging signal to generate a three-dimensional image, wherein the second direction intersects the first direction.
  • the strip imaging source includes a plurality of sub-imaging sources respectively disposed along the first direction, and the plurality of sub-imaging sources are capable of respectively emitting an imaging beam.
  • an angle between a central axis of the treatment beam from which the radiation therapy hair exits and a central axis of the imaging beam emitted by the plurality of sub-imaging sources is less than or equal to a predetermined angle.
  • the distance between two adjacent sub-imaging sources is less than or equal to a preset value.
  • the first direction and the second direction satisfy one of the following conditions:
  • the first direction is a central axis direction of the annular frame, and the second direction is a circumferential direction of the annular frame;
  • the first direction is a circumferential direction of the annular frame
  • the second direction is a central axis direction of the annular frame.
  • the annular frame includes a first end surface and a second end surface along a central axis direction of the annular frame;
  • the strip-shaped imaging source or the strip-shaped imager disposed along a circumferential direction of the annular frame has a predetermined distance from the first end surface or the second end surface.
  • the strip-shaped imaging source or the strip imager disposed along a circumferential direction of the annular frame is arcuate in shape.
  • the strip imager is a single row detector or a plurality of rows of detectors.
  • the apparatus includes at least two sets of strip imaging sources, the imaging beams emitted by the at least two sets of strip imaging sources being received by the same strip imager or respectively received by different strip imagers.
  • the two sets of strip imaging sources are disposed opposite one another on both sides of the radiation therapy head.
  • the apparatus further includes: a patient support device for supporting the patient; and processing means for receiving the three-dimensional imaging signal transmitted by the strip imager and generating a three-dimensional image of the affected part of the patient, and according to the The three-dimensional image adjusts the patient support device.
  • the image guided radiation therapy apparatus includes: an annular frame, and a radiation treatment head, a strip imaging source and a strip imager disposed on the annular frame.
  • the annular frame is rotatable about a central axis;
  • the radiation therapy head can emit a treatment beam;
  • the strip imaging source can emit a plurality of imaging beams, and the strip imaging source is disposed in a first direction near the radiation therapy head Position;
  • the strip imager may be disposed on a side opposite the strip imaging source in a second direction intersecting the first direction, and the strip imager may be configured to receive an imaging beam and convert the imaging beam into three-dimensional imaging The signal is used to generate a three-dimensional image of the affected part of the patient.
  • the image-guided radiotherapy apparatus does not need to rotate the strip-shaped imaging source and the strip imager with the annular gantry by a certain angle, and does not need to process the two-dimensional image acquired at different angles, and can generate the position reflecting the affected part of the patient in real time. Offset 3D image.
  • the therapeutic beam of the radiation therapy hair can be guided in time to accurately hit the affected part of the patient, and the image guides the radiotherapy apparatus to have higher radiotherapy precision.
  • FIG. 1 is a schematic structural view of a conventional image guided radiotherapy apparatus
  • FIG. 2 is a schematic structural diagram of an image guided radiotherapy apparatus according to an embodiment of the present disclosure
  • FIG. 3 is a comparison diagram of two adjacent sub-imaging sources having different distances according to an embodiment of the present disclosure
  • FIG. 4 is a schematic diagram showing the positional relationship between a strip imaging source and a radiation treatment head according to an embodiment of the present disclosure
  • FIG. 5 is a schematic diagram showing the relationship between another strip imaging source and a radiation treatment head according to an embodiment of the present disclosure
  • FIG. 6 is a schematic diagram showing an arrangement manner of a strip image forming source and a strip imager according to an embodiment of the present disclosure
  • FIG. 7 is a schematic diagram of another arrangement manner of a strip imaging source and a strip imager according to an embodiment of the present disclosure.
  • FIG. 8 is a schematic structural diagram of an image-guided radiotherapy apparatus having two sets of strip-shaped imaging sources according to an embodiment of the present disclosure
  • FIG. 9 is a schematic structural diagram of an image-guided radiotherapy apparatus including a patient support device and a treatment device according to an embodiment of the present disclosure.
  • FIG. 2 is a schematic structural diagram of an image guided radiotherapy apparatus according to an embodiment of the present disclosure.
  • the image-guided radiation therapy apparatus 1 can include an annular gantry 11, a radiation therapy head 12, a strip imaging source 13, and a strip imager 14.
  • the annular frame 11 is rotatable about the central axis CA.
  • a radiation therapy head 12 can be disposed on the annular frame 11 and the radiation therapy head 12 can be used to emit a treatment beam.
  • the strip imaging source 13 can be used to emit an imaging beam, and the strip imaging source 13 can be placed in a position close to the radiation therapy head 12 in the first direction S1.
  • the strip imager 14 may be disposed on the opposite side of the strip imaging source 13 in a second direction S2 that intersects the first direction S1, and the strip imager 14 may be configured to receive through the patient's affected part (target or target) The imaging beam of the region is converted into a three-dimensional imaging signal to generate a three-dimensional image of the affected part of the patient.
  • the imaging beam emitted by the strip imaging source 13 may be a quadrangular pyramid beam. And the imaging beam can pass through the affected part of the patient and be received by the strip imager 14 in real time.
  • the strip imager 14 can convert the received imaging beam into a three-dimensional imaging signal. And, the imaging device including the strip imaging source 13 and the strip imager 14 itself, or the processing device connected to the strip imager 14 can quickly generate a three-dimensional image of the current patient affected part according to the three-dimensional imaging signal, and The three-dimensional image can accurately reflect the deviation of the affected part of the patient. Therefore, the image-guided radiotherapy apparatus provided by the embodiment of the present disclosure can guide the treatment beam emitted by the radiation treatment head 12 to accurately hit the patient's affected part in real time.
  • the image-guided radiotherapy apparatus can generate a three-dimensional image reflecting the positional deviation of the affected part of the patient in real time, and can then guide the radiation treatment head 12 to perform radiation therapy on the affected part of the patient in real time.
  • the time for image processing is saved, the real-time of image guidance is improved, and the precision of radiation therapy is improved.
  • the strip-shaped imaging source 13 may include a plurality of sub-imaging sources 131, ..., 13i, ..., 13n, i having an integer greater than or equal to 1 and less than or equal to n, and n being an integer greater than one.
  • the plurality of sub-imaging sources 131, . . . , 13i, . . . , 13n can respectively emit imaging beams, and the plurality of sub-imaging sources 131, . . . , 13i, . . . , 13n can be disposed in the first direction S1 near the radiation therapy head 12. position.
  • the plurality of sub-imaging sources 131, ..., 13i, ..., 13n included in the strip-shaped imaging source 13 may be in a single row and arranged in a linear arrangement.
  • the plurality of sub-imaging sources 131, ..., 13i, ..., 13n in the strip imaging source 13 may also be arranged in a plurality of rows in an array.
  • the strip imaging source 13 can include an N-slot imaging source, N being an integer greater than one.
  • the strip imager 14 it can be a single row of detectors or multiple rows of detectors.
  • the plurality of sub-imaging sources 131, ..., 13i, ..., 13n included in the strip imaging source 13 are in a single row or in multiple rows, adjacent two sub-images of the strip-shaped imaging source 13 disposed along the first direction S1
  • the distance between the sources is less than or equal to a preset value.
  • the intersection between adjacent imaging beams is closer to the strip imaging source 13 than the arrangement with larger spacing of adjacent sub-imaging sources, with a larger imaging range.
  • the imaging beam intersection of sub-imaging source 131 and sub-imaging source 132 is P1.
  • the imaging beam intersection of the sub-imaging source 131 and the sub-imaging source 132' is P2.
  • the horizontal line where the intersection P2 is located is farther away from the strip-shaped imaging source 13, since the imaging beams of the sub-imaging source 131 and the sub-imaging source 132' are not crossed between the horizontal line where the intersection P1 is located and the horizontal line where the intersection P2 is located.
  • the imaging at the shadow is not obtained, and the imaging range is small.
  • the central axis of the treatment beam emitted by the radiation therapy head 12 and the central axis of the imaging beam emitted along the plurality of sub-imaging sources are less than or equal to a predetermined angle.
  • the preset angle here can be set as needed. Of course, the smaller the preset angle, the better.
  • the preset angle is 0, and the central axis of the treatment beam emitted by the radiation therapy head 12 and the central axis of the plurality of imaging beams emitted by the plurality of sub-imaging sources are equal to the preset clip. angle. That is, the angle between the central axis of the treatment beam emitted by the radiation therapy head 12 and the central axis of the imaging beam emitted by the plurality of sub-imaging sources is zero. Since the imaging beam emitted from the strip imaging source 13 and the treatment beam emitted from the radiation therapy head 12 may interfere with each other, the smaller the preset angle, the better, in the case of ensuring that they do not interfere with each other.
  • the central axis of the treatment beam is The central axis C1 of the volume that can be formed for a plurality of treatment beams, the central axis C1 passing through the intersection T.
  • the radiation treatment head 12 is a suitable intensity-modulating treatment head 122
  • the treatment beam emitted from the radiation source is conformed to the patient's affected part by the collimator.
  • the central axis of the treatment beam can then be the central axis C1' of the volume formed by the treatment beam, which axis axis C1' passes through the intersection T of the treatment beam.
  • the central axis of the imaging beam emitted by the sub-imaging source may be the line axis C2 of the center point of the strip-shaped imaging source 13 and the center point of the strip imager 14.
  • the second direction S2 intersects the first direction S1 in space, where the manner of intersection includes, but is not limited to, orthogonal.
  • the intersection of two directions in space may mean that the orthogonal projections of the two planes in the same plane intersect.
  • the first direction S1 is the central axis CA direction of the annular frame 11 as shown in FIG. 1, that is, the first direction S1 is parallel to the extending direction of the central axis CA.
  • This second direction S2 may be the circumferential direction of the annular frame 11.
  • the first direction S1 may be a circumferential direction of the annular frame 11
  • the second direction S2 may be a central axis CA direction of the annular frame 11.
  • the strip imaging source 13 intersects the arrangement direction of the strip imager 14, and when the strip imaging source 13 is disposed along the central axis CA direction, the strip imager 14 is disposed in the circumferential direction. Conversely, when the strip-shaped imaging source 13 is disposed in the circumferential direction, the strip imager 14 is disposed along the central axis CA direction.
  • the circumferential direction may refer to the circumferential direction of the annular frame 11 .
  • the strip imaging source 13 may be a horizontal strip imaging source as shown in FIG. 2 or an arc strip imaging source.
  • the strip imager 14 may be a flat panel detector as shown in FIG. 2 or a curved detector. That is, the shape of the strip-shaped imaging source 13 or the strip imager 14 disposed in the circumferential direction of the annular frame 11 is curved.
  • the annular frame 11 includes a first end surface 111 and a second end surface 112 along the central axis CA direction.
  • the strip-shaped imaging source 13 or the strip imager 14 disposed along the circumferential direction of the annular frame 11 is at a predetermined distance from the first end surface 111 or the second end surface 112 of the annular frame 11.
  • the predetermined distance here may be zero, that is, the strip-shaped imaging source 13 or the strip imager 14 disposed along the circumferential direction of the annular frame 11 is disposed adjacent to the first end surface 111 or the second end surface 112.
  • the preset distance may not be 0, and may be set as needed.
  • the image-guided radiation therapy apparatus includes a strip-shaped imaging source 13 as a group.
  • the device may also include at least two sets of strip imaging sources.
  • a strip imager 14 disposed opposite the at least two sets of strip imaging sources can receive the imaged beams emitted by the at least two sets of strip imaging sources 13.
  • the image guided radiation therapy device includes two sets of strip imaging sources 13A and 13B.
  • the strip imager 14 can simultaneously receive the imaging beams emitted by the two sets of strip imaging sources 13A and 13B.
  • the image guided radiation therapy apparatus can comprise: at least two sets of strip imaging sources, and at least two sets of strip imagers corresponding one to one of the at least two sets of strip imaging sources.
  • each component imager can be used to receive an imaging beam emitted by a corresponding group of imaging sources.
  • the image guided radiation therapy apparatus includes two sets of strip imaging sources 13A and 13B, and corresponding sets of strip imagers 14A and 14B.
  • the imager 14A is for receiving an imaging beam emitted by the imaging source 13A
  • the imager 14B is for receiving an imaging beam emitted by the imaging source 13B.
  • the two sets of strip-shaped imaging sources 13A and 13B may be oppositely disposed on both sides of the radiation therapy head 12.
  • the image-guided radiation therapy apparatus can further include a patient support device 15 and a processing device 16.
  • the patient support device 15 can be used to support a patient.
  • the processing device 16 can be configured to receive a three-dimensional imaging signal transmitted by the strip imager 14 and generate a three-dimensional image of the affected part of the patient, and to adjust the patient support device 15 in accordance with the three-dimensional image.
  • the patient support device 15 can be a treatment bed or a treatment seat, or other device for supporting a patient.
  • the processing device 16 can be a processing device having a processing function, such as a computer or a server.
  • the processing device 16 can be a host computer.
  • the embodiment of the present disclosure does not specifically limit this.

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Abstract

一种图像引导放射治疗设备（1），该图像引导放射治疗设备（1）包括：环形机架（11）、放射治疗头（12）、条状成像源（13）和条状成像器（14）。其中，该环形机架（11）能够绕中心轴（CA）旋转，该放射治疗头（12）可以设置于环形机架（11）上，且可以发出治疗束。该条状成像源（13）可以发出成像束，且可以沿第一方向（S1）设置于靠近放射治疗头（12）的位置。该条状成像器（14）可以沿与第一方向（S1）相交的第二方向（S2）设置于条状成像源（13）的对侧，用于接收成像束，并将该成像束转化为三维成像信号以生成患者患部的三维图像。

Description

一种图像引导放射治疗设备
本公开要求于2018年04月11日提交的申请号为201810321113.X、发明名称为“一种图像引导放射治疗设备”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。
技术领域
本公开涉及放射治疗技术领域，尤其涉及一种图像引导放射治疗设备。
背景技术
图像引导放射治疗(Image Guided Radiation Therapy，IGRT)技术可以通过成像装置对患者靶区在治疗前进行定位，以及对患者靶区在治疗中进行实时定位跟踪。可以降低在治疗过程中，对肿瘤周围的正常组织及关键器官造成损伤的概率，从而实现对肿瘤的精确放射治疗。
图1为一种传统的图像引导放射治疗设备，如图1所示，该放射治疗设备包括能够绕中心轴旋转的环形机架01，设置于该环形机架01上的放射治疗头02(例如多源聚焦治疗头)以及成像装置。其中，放射治疗头02可以发出治疗束对患者的肿瘤靶区(靶区位于中心轴上)进行放射治疗。成像装置可以由相对设置的成像源03和成像器04组成，且该成像装置可以与放射治疗头02呈90度设置在该环形机架01上，该成像装置可以产生锥形成像束且可以采集肿瘤靶区的二维图像。
在使用传统的图像引导放射治疗设备进行图像引导放射治疗时，由于成像装置在如图1所示的位置仅可以采集到关于y轴和z轴所在平面的肿瘤靶区在位置A的二维图像，而该二维图像无法反映出肿瘤靶区在x轴方向的位置偏移，例如无法反映出肿瘤靶区从位置A偏移到位置A’的位置偏移。因此，成像装置还需要在环形机架01的带动下旋转一定的角度，并在该角度下采集肿瘤靶区的二维图像。之后，图像引导放射治疗设备可以将获取到的多个二维图像进行重建得到三维图像，再将三维图像与治疗计划中的三维图像进行配准得到患者肿瘤靶区的位置偏移。最后即可以根据该肿瘤靶区的位置偏移 调整治疗床，使得放射治疗头02发出的治疗束可以命中肿瘤靶区。
然而，在成像装置在一定角度获取肿瘤靶区的二维图像到重建生成三维图像，再到根据该三维图像配准得到患者肿瘤靶区的位置偏移的过程中，患者肿瘤靶区的位置可能再次发生偏移，例如从图1所示的位置A’再次偏移到位置A与A’之间的某一位置。这样，就可能导致放射治疗02头发出的治疗束命中的位置并非当前肿瘤靶区所在的位置A’，放射治疗的精度较低。
发明内容
本公开提供了一种图像引导放射治疗设备，该图像引导放射治疗设备可以实时的追踪肿瘤靶区的位置偏移并根据位置偏移引导放射治疗头进行放射治疗，可以解决相关技术中放射治疗精度不高的问题。
本公开实施例提供了一种图像引导放射治疗设备，所述设备包括：环形机架，能够绕中心轴旋转；放射治疗头，设置于所述环形机架上，用于发出治疗束；条状成像源，用于发出成像束，所述条状成像源沿第一方向设置于靠近所述放射治疗头的位置；条状成像器，沿第二方向设置于所述条状成像源的对侧，用于接收成像束，并用于将所述成像束转化为三维成像信号以生成三维图像，其中，所述第二方向与所述第一方向相交。
在一实施例中，所述条状成像源包括多个子成像源，所述多个子成像源分别沿所述第一方向设置，且所述多个子成像源能够分别发出成像束。
在一实施例中，所述放射治疗头发出的治疗束的中心轴，与所述多个子成像源发出的成像束的中心轴之间的夹角小于或等于预设夹角。
在一实施例中，相邻的两个所述子成像源之间的距离小于或等于预设值。
在一实施例中，所述第一方向和所述第二方向满足下述条件中的一种：
所述第一方向为所述环形机架的中心轴方向，所述第二方向为所述环形机架的周向方向；
所述第一方向为所述环形机架的周向方向，所述第二方向为所述环形机架的中心轴方向。
在一实施例中，所述环形机架沿所述环形机架的中心轴方向包括：第一端面和第二端面；
沿所述环形机架的周向方向设置的所述条状成像源或者所述条状成像器，距所述第一端面或者所述第二端面的距离均为预设距离。
在一实施例中，沿所述环形机架的周向方向设置的所述条状成像源或者所述条状成像器的形状均为弧形。
在一实施例中，所述条状成像器为单排探测器或者多排探测器。
在一实施例中，所述设备包括至少两组条状成像源，所述至少两组条状成像源发出的成像束被同一条状成像器接收，或者分别被不同的条状成像器接收。
在一实施例中，在所述设备包括两组条状成像源的情况下，所述两组条状成像源相对设置于所述放射治疗头的两侧。
在一实施例中，所述设备还包括：患者支撑装置，用于支撑患者；处理装置，用于接收所述条状成像器发送的三维成像信号并生成患者患部的三维图像，以及根据所述三维图像调整所述患者支撑装置。
与现有技术相比，本公开实施例提供的图像引导放射治疗设备包括：环形机架，以及设置于该环形机架上的放射治疗头、条状成像源和条状成像器。其中，该环形机架可绕中心轴旋转；该放射治疗头可以发出治疗束；该条状成像源可以发出多条成像束，且该条状成像源沿第一方向设置于靠近放射治疗头的位置；该条状成像器可以沿与第一方向相交的第二方向设置于条状成像源的对侧，且该条状成像器可以用于接收成像束，并将该成像束转化为三维成像信号以生成患者患部的三维图像。
由于该条状成像器可以将条状成像源发出的成像束转化为三维图像。因此，该图像引导放射治疗设备无需条状成像源和条状成像器随环形机架旋转一定角度，也无需对不同角度下获取的二维图像进行处理，就可以实时生成反映出患者患部的位置偏移的三维图像。进而可以及时引导放射治疗头发出的治疗束准确命中患者患部，该图像引导放射治疗设备的放射治疗精度较高。
本公开的其它特征和优点将在随后的说明书中阐述，并且，部分地从说明书中变得显而易见，或者通过实施本公开而了解。本公开的目的和其他优点可通过在说明书、权利要求书以及附图中所特别指出的结构来实现和获得。
附图说明
附图用来提供对本公开技术方案的进一步理解，并且构成说明书的一部分，与本申请的实施例一起用于解释本公开的技术方案，并不构成对本公开技术方案的限制。
图1为一种传统的图像引导放射治疗设备的结构示意图；
图2为本公开实施例提供的一种图像引导放射治疗设备的结构示意图；
图3为本公开实施例相邻两个子成像源具有不同距离的对比图；
图4为本公开实施例中一种条状成像源与放射治疗头位置关系示意图；
图5为本公开实施例中另一种条状成像源与放射治疗头位置关系示意图；
图6为本公开实施例中条状成像源和条状成像器的一种设置方式示意图；
图7为本公开实施例中条状成像源和条状成像器另一种设置方式示意图；
图8为本公开实施例提供的具有两组条状成像源的图像引导放射治疗设备的结构示意图；
图9为本公开实施例提供的包括患者支撑装置和处理装置的图像引导放射治疗设备的结构示意图。
具体实施方式
为使本公开的目的、技术方案和优点更加清楚明白，下文中将结合附图对本公开的实施例进行详细说明。需要说明的是，在不冲突的情况下，本申请中的实施例及实施例中的特征可以相互任意组合。
图2为本公开实施例提供的一种图像引导放射治疗设备的结构示意图。如图2所示，该图像引导放射治疗设备1可以包括：环形机架11、放射治疗头12、条状成像源13和条状成像器14。其中，环形机架11能够绕中心轴CA旋转。放射治疗头12可以设置于该环形机架11上，且该放射治疗头12可以用于发出治疗束。条状成像源13可以用于发出成像束，且该条状成像源13可以沿第一方向S1设置于靠近放射治疗头12的位置。条状成像器14可以沿与该第一方向S1相交的第二方向S2设置于条状成像源13的对侧，且该条状成像器14可以用于接收穿过患者患部(靶点或靶区)的成像束，并将该成像束转化为三维成像信号以生成患者患部的三维图像。
在使用上述图像引导放射治疗设备进行放射治疗时，该条状成像源13发出的成像束可以为偏四棱锥束。且该成像束可以穿过患者患部，被条状成像器14实时接收。
由于该条状成像器14可以将接收到的成像束转化为三维成像信号。并且，由于包括上述条状成像源13和条状成像器14的成像装置自身，或者与条状成像器14相连接的处理装置可以根据该三维成像信号快速生成当前患者患部的三维图像，且该三维图像可以准确反映出患者患部发生的偏移。因此本公开实施例提供的图像引导放射治疗设备可以实时引导放射治疗头12发出的治疗束准确命中患者患部。与相关技术相比，该图像引导放射治疗设备可以实时生成反映出患者患部的位置偏移的三维图像，进而可以实时引导放射治疗头12对患者患部进行放射治疗。节省了图像处理的时间，提高了图像引导的实时性，并且提高了放射治疗的精度。
参考图2，该条状成像源13可以包括多个子成像源131，…，13i，…，13n，i大于等于1且小于等于n的整数，n为大于1的整数。并且，该多个子成像源131，…，13i，…，13n能够分别发出成像束，该多个子成像源131，…，13i，…，13n可以沿第一方向S1设置于靠近放射治疗头12的位置。
对于条状成像源13，如图2所示，条状成像源13包括的多个子成像源131，…，13i，…，13n可以为单排，呈线性排布。当然，条状成像源13中的多个子成像源131，…，13i，…，13n也可以为多排，呈阵列排布。示例性的，条状成像源13可以包括N排子成像源，N为大于1的整数。对于条状成像器14，它可以为单排探测器，也可以为多排探测器。
一方面，不论条状成像源13包括的多个子成像源131，…，13i，…，13n为单排还是多排，该条状成像源13中沿第一方向S1设置的相邻两个子成像源(例如，子成像源131和132)之间的距离小于等于预设值。这样，与相邻子成像源具有较大间距的设置方式相比，相邻成像束之间的交叉点更靠近条状成像源13，具有较大的成像范围。
示例的，如图3所示，当相邻两个子成像源131和子成像源132之间的距离为d时，子成像源131和子成像源132的成像束交叉点为P1。当子成像源131与相邻子成像源132’之间的距离为d’，并且d’大于d时，子成像源131 和子成像源132’的成像束交叉点为P2。由图3可知，交叉点P2所在的水平线更远离条状成像源13，由于子成像源131和子成像源132’的成像束均未穿过交叉点P1所在水平线与交叉点P2所在水平线之间的阴影处，因此，在相邻子成像源131和132具有较大间距的设置方式下，阴影处的成像是无法被获取的，成像范围较小。
另一方面，不论条状成像源13包括的子成像源131，…，13i，…，13n为单排还是多排。如图2所示，放射治疗头12发出的治疗束的中心轴，与沿多个子成像源发出的成像束的中心轴之间的夹角小于或等于预设夹角。这里的预设夹角可以根据需要进行设定。当然，预设夹角越小越好。理想状态下，该预设夹角为0，且该放射治疗头12发出的治疗束的中心轴，与多个子成像源发出的多个成像束的中心轴之间的夹角等于该预设夹角。也即是，该放射治疗头12发出的治疗束的中心轴，与多个子成像源发出的成像束的中心轴之间的夹角均为0。由于条状成像源13发出的成像束与放射治疗头12发出的治疗束之间可能会相互干扰，因此，在保证它们之间不相互干扰的情况下，该预设角度越小越好。
这里需要说明的是，一方面，如图4所示，若放射治疗头12为多源聚焦放射治疗头121，多个放射源发出的治疗束可以聚焦于交点T，则治疗束的中心轴即可以为多个治疗束形成的体积的中心轴C1，该中心轴C1经过交点T。
另一方面，如图5所示，若放射治疗头12为适型调强治疗头122，放射源发出的治疗束经准直器适形后照射患者患部。则治疗束的中心轴可以为该治疗束形成的体积的中心轴C1’，该中心轴C1’经过治疗束的交点T。
并且，参考图4和图5，该子成像源发出的成像束的中心轴可以为条状成像源13的中心点与条状成像器14的中心点的连线轴C2。
又如图2所示，第二方向S2与第一方向S1在空间中是相交的，这里，相交的方式包括但不限于正交。其中，两个方向在空间中相交可以是指：两个方向在同一平面的正投影相交。更为详尽的，该第一方向S1为如图1所示的环形机架11的中心轴CA方向，也即是，该第一方向S1与中心轴CA的延伸方向平行。该第二方向S2可以为环形机架11的周向方向。或者，该第一方向S1可以为环形机架11的周向方向，该第二方向S2可以为环形机架11 的中心轴CA方向。
通过上述描述可知，条状成像源13与条状成像器14的设置方向是相交的，条状成像源13沿中心轴CA方向设置时，条状成像器14沿周向方向设置。相反的，条状成像源13沿周向方向设置时，条状成像器14沿中心轴CA方向设置。其中，该周向方向可以是指该环形机架11的周长方向。
这里需要说明的是，上述条状成像源13可以为如图2所示的水平条状成像源，也可以为弧形条状成像源。相应的，上述条状成像器14可以为如图2所示的平板探测器，也可以为弧形探测器。也即是，该环形机架11的周向方向设置的条状成像源13或者条状成像器14的形状为弧形。
继续参考图2，该环形机架11沿中心轴CA方向包括：第一端面111和第二端面112。沿该环形机架11的周向方向设置的条状成像源13或者条状成像器14，距该环形机架11的第一端面111或者第二端面112的距离均为预设距离。这里的预设距离可以为0，即沿该环形机架11的周向方向设置的条状成像源13或者条状成像器14紧邻该第一端面111或者第二端面112设置。当然，该预设距离也可以不为0，可以根据需要进行设定。
上述描述中，该图像引导放射治疗设备包括的条状成像源13为一组。然而，该设备还可以包括至少两组条状成像源。与该至少两组条状成像源相对设置的条状成像器14可以接收该至少两组条状成像源13发出的成像束。
示例性的，如图6所示，该图像引导放射治疗设备包括两组条状成像源13A和13B。条状成像器14可以同时接收两组条状成像源13A和13B发出的成像束。
或者，该图像引导放射治疗设备可以包括：至少两组条状成像源，以及与该至少两组条状成像源一一对应的至少两组条状成像器。其中，每组成像器可以用于接收对应的一组成像源发出的成像束。
示例性的，如图7所示，图像引导放射治疗设备包括两组条状成像源13A和13B，以及对应的两组条状成像器14A和14B。成像器14A用于接收成像源13A发出的成像束，成像器14B用于接收成像源13B发出的成像束。
如图8所示，在图像引导放射治疗设备包括两组条状成像源13A和13B的情况下，该两组条状成像源13A和13B可以相对设置于该放射治疗头12 的两侧。
如图9所示，该图像引导放射治疗设备还可以包括：患者支撑装置15和处理装置16。其中，该患者支撑装置15可以用于支撑患者。
该处理装置16可以用于接收条状成像器14发送的三维成像信号并生成患者患部的三维图像，以及根据三维图像调整患者支撑装置15。
这里需要说明的是，该患者支撑装置15可以为治疗床或治疗座椅，或其他用于支撑患者的装置。
该处理装置16可以为计算机或服务器等具有处理功能的处理设备，例如，该处理装置16可以为上位机。本公开实施例对此不作具体限定。
虽然本公开所揭露的实施方式如上，但所述的内容仅为便于理解本公开而采用的实施方式，并非用以限定本公开。任何本公开所属领域内的技术人员，在不脱离本公开所揭露的精神和范围的前提下，可以在实施的形式及细节上进行任何的修改与变化，但本公开的专利保护范围，仍须以所附的权利要求书所界定的范围为准。

Claims (11)

  1. 一种图像引导放射治疗设备，其特征在于，所述设备包括：
    环形机架，能够绕中心轴旋转；
    放射治疗头，设置于所述环形机架上，用于发出治疗束；
    条状成像源，用于发出成像束，所述条状成像源沿第一方向设置于靠近所述放射治疗头的位置；
    条状成像器，沿第二方向设置于所述条状成像源的对侧，用于接收成像束，并用于将所述成像束转化为三维成像信号以生成三维图像，其中，所述第二方向与所述第一方向相交。
  2. 根据权利要求1所述的设备，其特征在于，所述条状成像源包括多个子成像源，所述多个子成像源分别沿所述第一方向设置，且所述多个子成像源能够分别发出成像束。
  3. 根据权利要求2所述的设备，其特征在于，所述放射治疗头发出的治疗束的中心轴，与所述多个子成像源发出的成像束的中心轴之间的夹角小于或等于预设夹角。
  4. 根据权利要求2所述的设备，其特征在于，相邻的两个所述子成像源之间的距离小于或等于预设值。
  5. 根据权利要求1所述的设备，其特征在于，所述第一方向和所述第二方向满足下述条件中的一种：
    所述第一方向为所述环形机架的中心轴方向，所述第二方向为所述环形机架的周向方向；
    所述第一方向为所述环形机架的周向方向，所述第二方向为所述环形机架的中心轴方向。
  6. 根据权利要求5所述的设备，其特征在于，所述环形机架沿所述环形机架的中心轴方向包括：第一端面和第二端面；
    沿所述环形机架的周向方向设置的所述条状成像源或者所述条状成像器，距所述第一端面或者所述第二端面的距离均为预设距离。
  7. 根据权利要求5所述的设备，其特征在于，沿所述环形机架的周向方向设置的所述条状成像源或者所述条状成像器的形状均为弧形。
  8. 根据权利要求1所述的设备，其特征在于，所述条状成像器为单排探测器或者多排探测器。
  9. 根据权利要求1所述的设备，其特征在于，所述设备包括至少两组条状成像源，所述至少两组条状成像源发出的成像束被同一条状成像器接收，或者分别被不同的条状成像器接收。
  10. 根据权利要求9所述的设备，其特征在于，在所述设备包括两组条状成像源的情况下，所述两组条状成像源相对设置于所述放射治疗头的两侧。
  11. 根据权利要求1所述的设备，其特征在于，所述设备还包括：
    患者支撑装置，用于支撑患者；
    处理装置，用于接收所述条状成像器发送的三维成像信号并生成患者患部的三维图像，以及根据所述三维图像调整所述患者支撑装置。
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