WO2019156269A1 - Appareil pour la fabrication de suture médicale et procédé pour la fabrication de suture médicale - Google Patents

Appareil pour la fabrication de suture médicale et procédé pour la fabrication de suture médicale Download PDF

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Publication number
WO2019156269A1
WO2019156269A1 PCT/KR2018/001824 KR2018001824W WO2019156269A1 WO 2019156269 A1 WO2019156269 A1 WO 2019156269A1 KR 2018001824 W KR2018001824 W KR 2018001824W WO 2019156269 A1 WO2019156269 A1 WO 2019156269A1
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WO
WIPO (PCT)
Prior art keywords
suture
twist
yarn
compression units
suture yarn
Prior art date
Application number
PCT/KR2018/001824
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English (en)
Korean (ko)
Inventor
장민서
Original Assignee
(주)제이월드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by (주)제이월드 filed Critical (주)제이월드
Priority to PCT/KR2018/001824 priority Critical patent/WO2019156269A1/fr
Publication of WO2019156269A1 publication Critical patent/WO2019156269A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • D—TEXTILES; PAPER
    • D02—YARNS; MECHANICAL FINISHING OF YARNS OR ROPES; WARPING OR BEAMING
    • D02J—FINISHING OR DRESSING OF FILAMENTS, YARNS, THREADS, CORDS, ROPES OR THE LIKE
    • D02J3/00—Modifying the surface
    • D02J3/02—Modifying the surface by abrading, scraping, scuffing, cutting, or nicking

Definitions

  • the present invention relates to a medical suture manufacturing apparatus and a method of manufacturing a medical suture. More specifically, the present invention relates to a device for manufacturing a medical suture that can be stretched and molded, and a method of manufacturing a medical suture through the same.
  • sutures have been used to connect or suture damaged muscles, blood vessels, nerve tissue or wounds or surgical incisions.
  • sutures are used to remove tissues, sagging, wrinkles, etc. caused by double eyelid surgery or aging, decreased skin elasticity, trauma, overuse, necrosis, etc. in addition to surgical procedures. It is also used for such procedures.
  • a lifting procedure using a suture is a technique for lifting or pulling sagging skin and tissues of the face, jaw, neck, abdomen, vagina, chest, hips, etc. with a needle and thread without using a knife.
  • the skin does not need to be incised excessively, the occurrence of scars can be minimized, and bleeding or swelling due to surgery is being spotlighted.
  • the suture may include a plurality of protrusions (eg, barbs) on the surface to increase knots or lifting efficiency.
  • a separate incision or cutting process is required to form the protrusions on the suture outer surface.
  • Korean Patent Publication No. 10-1581865 discloses a medical suture manufacturing apparatus including a cutting portion (die cutter portion) to form protrusions on a suture surface.
  • a cutting portion die cutter portion
  • protrusions are formed on the outer surface of the suture through a direct cutting process, external damage of the suture may be inevitable, and a failure of suture may be caused during subsequent stretching.
  • Korean Patent Publication No. 10-1057377 also discloses a method for forming fine protrusions on a suture surface.
  • a method for preventing defects such as shape non-uniformity, breakage, etc. generated during the suture forming process.
  • One object of the present invention is to provide an apparatus for manufacturing a medical suture having excellent mechanical and shape reliability.
  • One object of the present invention is to provide a method of manufacturing a medical suture having excellent mechanical and shape reliability.
  • a suture feeder for supplying suture yarn;
  • a preheater for heating the suture yarn to a predetermined temperature; Pressing the suture yarn passing through the preheating unit in at least three directions and including at least three compression units arranged radially;
  • Medical suture manufacturing apparatus comprising a twist prevention portion for generating tension in the suture yarn to remove the twist generated in the preheating portion or the pressure forming portion.
  • each of the compression unit comprises a suture yarn is inserted into the groove, medical suture manufacturing apparatus.
  • each of the compression unit comprises a projection groove connected to the groove, medical suture manufacturing apparatus.
  • the projection groove comprises a first projection groove and a second projection groove inclined to face each other, medical suture manufacturing apparatus.
  • the compression units include three compression units radially arranged at 120 degrees ( o ) from each other around the suture yarn.
  • the compression units include four compression units arranged in each of the four quadrants divided by the vertical axis and the horizontal axis with the suture yarn as the origin.
  • the pressure forming part includes a first pressure forming part and a second pressure forming part spaced apart from each other in the longitudinal direction of the suture yarn
  • first press-molded part and the second press-molded part include compression units for pressing the suture yarn in a direction crossing each other.
  • the anti-twist portion comprises a tension roller, medical suture manufacturing apparatus.
  • the pressure forming portion is disposed between the first anti-twist portion and the second anti-twist portion, medical suture manufacture Device.
  • the anti-twist portion includes a first anti-twist portion, a second anti-twist portion and a third anti-twist portion
  • the pressurized molded part is disposed between the first twist prevention part and the second twist prevention part, and the preheating part is disposed between the second twist prevention part and the third twist prevention part.
  • step of pressing the suture yarn comprises forming a suture projection, medical suture manufacturing method.
  • Medical suture manufacturing apparatus includes a preheating portion and the anti-twisting portion, the twisting, twisting phenomenon of the suture generated in the preheating portion by the tension force by the anti-twisting portion can be buffered or removed. Therefore, it is possible to obtain a suture significantly improved thickness and shape uniformity.
  • the press-molded part may be further disposed between the preheating part and the kink-preventing part, and defects such as suture agglomeration, molding non-uniformity, etc. may be suppressed in the press-molded part by the tensile force by the kink-preventing part.
  • Medical suture manufacturing apparatus may include a pressure molding portion for compression molding the suture in at least three directions.
  • sutures having the desired thickness or diameter can be formed with improved precision.
  • the press-molded part includes a groove part for forming the protrusion, and thus, the protrusion forming may be performed together with the pressing process. Therefore, it is possible to prevent damage to the suture by a separate cutting or cutting process.
  • FIG. 1 is a schematic configuration diagram showing an apparatus for manufacturing a medical suture in accordance with some embodiments of the present invention.
  • FIGS 2 and 3 are schematic cross-sectional views for explaining the structure of the press-molded part according to some embodiments of the present invention.
  • FIG. 4 is a schematic diagram showing the shape of the projection groove in the compression unit according to some embodiments of the invention.
  • FIG. 5 is a schematic perspective view for explaining the structure of the press-molded part according to some embodiments of the present invention.
  • FIGS. 6 and 7 are schematic perspective and cross-sectional views, respectively, showing a suture made in accordance with some embodiments of the present invention.
  • FIGS. 8 and 9 are schematic perspective and cross-sectional views, respectively, showing a suture made in accordance with some embodiments of the present invention.
  • FIG. 10 is a schematic cross-sectional view showing a suture made in accordance with some embodiments of the present invention.
  • FIG. 11 is a schematic diagram illustrating an apparatus for manufacturing a medical suture in accordance with some embodiments of the present invention.
  • FIG. 12 is a schematic diagram illustrating an apparatus for manufacturing a medical suture in accordance with some embodiments of the present invention.
  • FIGS. 1 to 3 are schematic configuration diagram showing an apparatus for manufacturing a medical suture in accordance with some embodiments of the present invention.
  • 2 and 3 are schematic cross-sectional views for explaining the structure of the press-molded part according to some embodiments of the present invention. A method of manufacturing a medical suture is also described with reference to FIGS. 1 to 3.
  • the medical suture manufacturing apparatus 100 includes a suture supply unit 110, a preheating unit 120, a twist prevention unit 130, a protrusion forming unit 140, a twister 150, a cutting unit 160, and It may include a winding unit 170.
  • the suture supply unit 110 may include, for example, a spool structure in which the suture yarn 50 may be wound and supplied.
  • Suture yarn 50 may comprise a bioabsorbable polymer or a bioabsorbable polymer.
  • Suture yarn 50 is, for example, polydioxanone, poly- (l-actic acid), polyglycolicacid, polycaprolactone, or copolymers thereof At least one selected from among the bioabsorbable polymer material.
  • the suture yarn 50 may include, for example, at least one bio-absorbent polymer material selected from polyprophylene, nylon, or a mixture thereof.
  • the suture yarn 50 is discharged from the suture feeder 110 and, for example, through the first guide roller 115, the preheating portion 120, the anti-twist portion 130, and the protrusion forming portion. By passing through 140 can be made into a suture.
  • the suture yarn 50 may be heated to facilitate, for example, suture molding in the protrusion forming unit 140 and / or the twister 150.
  • the preheating unit 120 may be designed to increase the ductility of the suture yarn 50 to improve processability, but to heat the suture yarn 50 in a temperature range that does not deform the polymer material or damage the polymer crystallinity.
  • a heating wire may be built in the preheater 120, and a temperature sensor, a temperature controller, or the like for controlling the temperature of the heating wire may be included.
  • the preheater 120 may be heated to a temperature above the glass transition temperature (Tg) and below the melting point (Tm) of the suture yarn 50.
  • the suture yarn 50 may be heated to a temperature in the range C). Heating temperature in preheater 120 is Tm-40 If it exceeds C, the suture yarn 50 may be twisted or shrunk to such an extent that restoration is difficult in the preheating unit 120. Heating temperature in preheater 120 is Tm-80 If less than C, subsequent molding processes can be difficult.
  • the suture yarn 50 when the melting point of the suture yarn 50 is about 120 ° C. includes polydioxanone, the suture yarn 50 may be heated to a temperature of about 40 to 80 ° C. through the preheating unit 120. have.
  • the heating temperature in the preheating unit 120 may be in the range of Tm-80 ° C. to Tm-60 ° C. in consideration of ease of forming process and relaxation of the shrinkage and twist of the suture yarn 50.
  • the suture yarn 50 passed through the preheater 120 may be twisted, shrunk, agglomerated, etc., generated in the preheater 120 by the anti-twist 130.
  • the anti-twist 130 may have a tension roller form in which the suture yarn 50 drawn from the preheater 120 is stretched to lump and straighten the twisted portion.
  • the twist prevention unit 130 may include an upper roller and a lower roller, and the suture yarn 50 may pass between the upper roller and the lower roller to be discharged in a state where the twist is removed to the suture before forming the protrusion. .
  • the twist prevention unit 130 may also perform a compression roller function. For example, the thickness and width of the suture yarn 50 through the twist prevention unit 130 may be reduced through the compressive force to be discharged to the suture of a predetermined size.
  • the anti-twist 130 may include a heating member, such as a heating wire that is temperature adjustable, on or inside the surface.
  • the anti-twist 130 may include a metal material to improve thermal conductivity efficiency.
  • the suture yarn 50 may be in contact with the suture yarn 50 in a temperature range substantially similar to or slightly lower than that of the preheater 120, and may remove wrinkles, kinks, and aggregates.
  • the temperature of the anti-twist 130 may be within a range of about ⁇ 10 ° C. at the heating temperature of the preheater 120. Applying a tensile force to the suture yarn 50 in the above temperature range can remove the kink generated in the preheating unit 120 while preventing local wrinkles, damage.
  • the tensile force applied through the anti-twist 130 may be adjusted in a range to prevent excessive thinning, breaking, deformation, etc. of the suture yarn 50 while sufficiently removing the twist of the suture yarn 50 of the polymer material. have.
  • a tensile force of about 5 to 10N may be applied through the anti-twist portion 130. When the tensile force is less than about 5N, sufficient kink, wrinkle removal effect may not be implemented. When the tensile force exceeds about 10N, thinning and deformation of the suture yarn 50 may be caused.
  • the suture passing through the anti-twist 130 may be molded into a desired shape by the protrusion forming unit 140 and / or the twister 150.
  • the protrusion forming part 140 may form an incision line for forming a barb or a protrusion along the length direction of the suture.
  • the protrusion forming unit 140 may include a cutter for forming the incision line.
  • the protrusion forming part 140 may function as a die cut molding part which forms an incision along with compression from the upper and lower parts of the suture.
  • the suture formed by the protrusion forming unit 140 is formed by the suture line is rotated by the twister 150, for example, the protrusions are arranged in a spiral rotation can be formed in the suture.
  • the protruding portion 140 and the twister 150 may be omitted.
  • a barb or a protrusion of the suture is formed in the press-molded part 200 to prevent damage to the suture by a separate cutting and rotating process.
  • the press-molded part 200 may be disposed between the preheater 120 and the anti-twist 130. Accordingly, when protrusions are formed in the press-molded part 200, it is possible to prevent protrusion molding defects due to twisting and agglomeration of the suture yarn 50.
  • the suture yarn 50 preheated by the preheating unit 120 may be compression molded in the pressure forming unit 200. Therefore, the suture yarn 50 can be easily converted into a suture molded into a desired shape by the pressure forming part 200.
  • the rear end of the medical suture manufacturing apparatus 100 may be a cutting unit 160 that can be cut to a predetermined length or unit of the suture is completed.
  • the winding unit 170 may be disposed to wind the suture manufactured.
  • the press-molded part 200 may include a plurality of compression units for press-molding the suture yarn 50 in at least three different directions.
  • each said compression unit may comprise a molding groove which functions substantially as a compression mold or a molding mold.
  • the press-molded part 200 may include three compression units 210a, 210b, and 210c.
  • Each of the compression units 210a, 210b, and 210c may include a groove portion 212 into which the suture yarn 50 may be inserted and molded.
  • the groove portion 212 may be integrally connected with the projection groove 212a for forming a projection such as barb on the suture yarn 50.
  • the suture yarn 50 may be compressed in three directions by the groove portion 212, and may be pressed into the protrusion groove 212a to form protrusions on the surface thereof.
  • the compression units 210a, 210b, 210c are sutured yarns 3 along three axes radiated in a direction of about 120 degrees o from each other with the suture yarn 50 as the origin. 50) can be arranged around. Therefore, the protrusions can be formed three-dimensionally by the compression units 210a, 210b, and 210c arranged in the three axis direction.
  • the press-molded part 200 may include four compression units 213a, 213b, 213c, and 213d.
  • Each of the compression units 213a, 213b, 213c, and 213d may include a groove portion and a protrusion groove into which the suture yarn 50 is inserted and molded. Therefore, the suture yarn 50 is compressed in four directions by the groove portion, and the suture yarn 50 may be pressed into the protrusion groove to form protrusions on the surface.
  • the compression units 213a, 213b, 213c, 213d may be arranged in each of the four quadrants divided by the vertical and horizontal axes with the suture yarn 50 as the origin. . Therefore, the suture yarn 50 can be formed in three dimensions while the suture yarn 50 is press-molded from four directions.
  • the press-molded part 200 may include five or more compression units.
  • the compression units can be arranged along the same plane across the suture yarn 50, or in a circle around the suture yarn 50.
  • the medical suture manufacturing apparatus 100 includes a pressure molded part 200, the pressure molded part 200 is arranged in three or more directions to apply a pressure to the suture yarn Can include them. Therefore, a suture having a desired diameter and width from one press-molded part 200 can be produced without additional equipment (for example, a pressure roller). In addition, when pressed in two directions it is possible to prevent the suture from being too flat and to manufacture a substantially circular suture accurately.
  • the compression unit may include a protrusion groove therein, and may be formed so that the protrusions are arranged in three dimensions with pressure molding.
  • the protrusions may be implemented without a separate cutting process or cutting equipment for forming protrusions or barbs.
  • the protrusion or the barb may be formed through the structure / configuration of the pressure forming part 200 described above.
  • FIG. 4 is a schematic diagram showing the shape of the projection groove in the compression unit according to some embodiments of the invention.
  • one compression unit 211 included in the pressure molding part 200 may include a groove 212 and protrusion grooves 212a and 212b therein as described with reference to FIG. 2.
  • the plurality of protrusion grooves may be connected to the groove portion 212 and arranged along the longitudinal direction of the suture.
  • the protrusion grooves 212a and 212b may include, for example, protrusion groove groups having a triangular cross section and inclined in opposite directions.
  • Group 212b may be included.
  • the suture may include a plurality of protrusions arranged in an orientation facing each other by the above-described protrusion groove shape, and thus fixing ability to the skin may be improved.
  • FIG. 5 is a schematic perspective view for explaining the structure of the press-molded part according to some embodiments of the present invention.
  • the pressure molding part 200 may include a first pressure molding part 220 and a second pressure molding part 230 spaced apart from each other along the length direction of the suture.
  • the first press molding part 220 and the second press molding part 230 may be arranged to apply pressure in a direction crossing each other.
  • the first press-molded part 220 compresses the suture yarn 50 in the z-axis direction to form compression units 225a and 225b.
  • Protrusion grooves protruding in the z-axis direction may be formed in each compression unit of the first press-molded part 220.
  • the second press-molded part 230 may include compression units 235a and 235b for compression molding the suture yarn 50 in the y-axis direction. Protrusion grooves protruding in the y-axis direction may be formed in each compression unit of the second pressure forming part 230.
  • each press-molded part includes a pair of compression units
  • the plurality of press-molded parts may be arranged to be spaced apart from each other, and the cross-pressing directions may be arranged to form substantially three-dimensional protrusions.
  • the height or thickness of the suture is adjusted by the first press-molded part 220, and the width of the suture is adjusted by the second press-molded part 230, thereby precisely manufacturing a suture having a desired dimension.
  • FIGS. 6 and 7 are schematic perspective and cross-sectional views, respectively, showing a suture made in accordance with some embodiments of the present invention.
  • the suture may include a body 60 and protrusions 65a and 65b integrally formed from the body 60.
  • the protrusions may include a first protrusion 65a and a second protrusion 65b which are inclined in opposite directions and face each other.
  • the press-molded portion of the medical suture manufacturing apparatus includes three compression units 210a, 210b, and 210c as shown in FIG. 2, three projections (around the body 60 on the same cross section) 65a, 65b) can be arranged radially.
  • FIGS. 8 and 9 are schematic perspective and cross-sectional views, respectively, showing a suture made in accordance with some embodiments of the present invention.
  • the suture may include a body 70 and protrusions 75a and 75b integrally formed from the body 70.
  • the protrusions include a first protrusion 75a and a second protrusion 75b which are formed to face each other in opposite directions and face each other.
  • the press-molded portion of the medical suture making device includes four compression units 213a, 213b, 213c, and 213d as shown in FIG. 3, four protrusions around the body 70 on the same cross section.
  • the fields 75a and 75b may be arranged radially.
  • FIG. 10 is a schematic cross-sectional view showing a suture made in accordance with some embodiments of the present invention.
  • the first protrusion 62a formed on the suture body 60, and the first protrusion 62a may be arranged to be offset from each other at a predetermined angle ⁇ .
  • the three-dimensionally formed protrusions can be arranged in a spiral form.
  • FIG. 11 is a schematic diagram illustrating an apparatus for manufacturing a medical suture in accordance with some embodiments of the present invention. Detailed descriptions of substantially the same or similar structures and structures as those described with reference to FIG. 1 will be omitted.
  • the medical suture manufacturing apparatus 102 may include a twist prevention portion 130, a first twist prevention portion 132 and a second twist prevention portion 134.
  • the press-molded part 200 may be disposed between the first twist preventer 132 and the second twist preventer 134.
  • the press-molded part 200 may include a plurality of compression units, for example, as described with reference to FIGS. 2, 3, and 5, and each compression unit may include a protrusion groove.
  • each compression unit may include a protrusion groove.
  • the anti-twist portions 132 and 134 are disposed at the front and rear ends of the press-molded portion 200, respectively, it is possible to more effectively prevent protrusion molding defects due to twisting and agglomeration in the press-molded portion 200 when forming the protrusions. Can be.
  • the uniformity of protrusion molding may be further improved.
  • the protrusion forming part 140 and the twister 150 may be omitted.
  • FIG. 12 is a schematic diagram illustrating an apparatus for manufacturing a medical suture in accordance with some embodiments of the present invention.
  • the twist prevention portion of the medical suture manufacturing device 104 may include first to third twist prevention portions 132, 134, and 136.
  • the pressure shaping portion 200 is disposed between the first twist prevention portion 132 and the second twist prevention portion 134, and the second twist prevention portion 134 and the third twist prevention.
  • the preheating unit 120 may be disposed between the units 136.
  • the second anti-twist portion 134 and the third anti-twist portion 136 are disposed at the front end and the rear end of the preheater 120, thermal deformation and agglomeration of the suture yarn 50 in the preheater 120. Can be suppressed.
  • the first twist prevention part 132 and the second twist prevention part 134 are disposed at the front end and the rear end of the pressure shaping part 200, respectively, to prevent defects in molding of the suture in the pressure shaping part 200. Uniformly shaped projections can be formed

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Textile Engineering (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention comprend : une partie d'alimentation de suture pour fournir un fil de suture ; une partie de préchauffage pour chauffer le fil de suture à une température prédéfinie ; une partie de formage à la presse pour presser le fil de suture passé à travers la partie de préchauffage dans au moins trois directions et comprenant au moins trois unités de compression disposées radialement ; et une partie de prévention de torsion pour générer une tension dans le fil de suture afin d'éliminer la torsion générée dans la partie de préchauffage ou la partie de formage à la presse. Il est possible de fabriquer une suture ayant une forme uniforme sans endommager la suture par la partie de formage à la presse et la partie de prévention de torsion.
PCT/KR2018/001824 2018-02-12 2018-02-12 Appareil pour la fabrication de suture médicale et procédé pour la fabrication de suture médicale WO2019156269A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/KR2018/001824 WO2019156269A1 (fr) 2018-02-12 2018-02-12 Appareil pour la fabrication de suture médicale et procédé pour la fabrication de suture médicale

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Application Number Priority Date Filing Date Title
PCT/KR2018/001824 WO2019156269A1 (fr) 2018-02-12 2018-02-12 Appareil pour la fabrication de suture médicale et procédé pour la fabrication de suture médicale

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WO2019156269A1 true WO2019156269A1 (fr) 2019-08-15

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101581865B1 (ko) * 2014-12-26 2015-12-31 (주)제이월드 의료용 봉합사 제조 장치 및 봉합사 제조 방법
KR101642962B1 (ko) * 2015-11-05 2016-07-26 (주)제이월드 봉합사 및 그 제조 방법
KR20170044454A (ko) * 2015-10-15 2017-04-25 박래경 돌기를 가진 매선로프 제조장치
KR101779922B1 (ko) * 2017-01-04 2017-09-19 (주)제이월드 의료용 봉합사 제조 장치 및 의료용 봉합사의 제조 방법
KR101806150B1 (ko) * 2017-01-04 2017-12-07 (주)제이월드 의료용 봉합사 제조 장치 및 의료용 봉합사의 제조 방법

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101581865B1 (ko) * 2014-12-26 2015-12-31 (주)제이월드 의료용 봉합사 제조 장치 및 봉합사 제조 방법
KR20170044454A (ko) * 2015-10-15 2017-04-25 박래경 돌기를 가진 매선로프 제조장치
KR101642962B1 (ko) * 2015-11-05 2016-07-26 (주)제이월드 봉합사 및 그 제조 방법
KR101779922B1 (ko) * 2017-01-04 2017-09-19 (주)제이월드 의료용 봉합사 제조 장치 및 의료용 봉합사의 제조 방법
KR101806150B1 (ko) * 2017-01-04 2017-12-07 (주)제이월드 의료용 봉합사 제조 장치 및 의료용 봉합사의 제조 방법

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