WO2019155895A1 - Dispositif d'hémodialyse implantable - Google Patents

Dispositif d'hémodialyse implantable Download PDF

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Publication number
WO2019155895A1
WO2019155895A1 PCT/JP2019/002213 JP2019002213W WO2019155895A1 WO 2019155895 A1 WO2019155895 A1 WO 2019155895A1 JP 2019002213 W JP2019002213 W JP 2019002213W WO 2019155895 A1 WO2019155895 A1 WO 2019155895A1
Authority
WO
WIPO (PCT)
Prior art keywords
housing
blood
dialysate
filtrate
membrane
Prior art date
Application number
PCT/JP2019/002213
Other languages
English (en)
Japanese (ja)
Inventor
則尚 三木
藍 渡邊
能士 大田
Original Assignee
学校法人 慶應義塾
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 学校法人 慶應義塾 filed Critical 学校法人 慶應義塾
Priority to JP2019570668A priority Critical patent/JPWO2019155895A1/ja
Publication of WO2019155895A1 publication Critical patent/WO2019155895A1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration

Definitions

  • the hemodialyzer preferably has a filtration device 71 for filtering blood.
  • the filtration device 71 includes a second housing 73, a blood filtration membrane 61, and a filtrate discharge part 63.
  • This blood filtration membrane 61 is connected to the arterial blood circuit 7 and is a membrane for filtering blood that does not flow into the first housing 3 but flows into the second housing 73.
  • the blood channel layer 43 is a layer provided in the first housing 3 and having the blood channel 41.
  • the blood flow path 41 is a blood flow path for guiding the blood flowing into the first housing 3 to the venous blood circuit 11.
  • the dialysate flow path layer 47 is a layer provided in the first housing 3 and having the dialysate flow path 45.
  • the dialysate flow path 45 is a dialysate flow path for guiding the dialysate flowing into the first housing 3 to the dialysate discharge section 31.
  • the dialysate channel 45 may be connected to the dialysate inlet and the dialysate outlet.
  • the hemodiafiltration membrane 5 is interposed between the blood channel layer 43 and the dialysate channel layer 47 and diafilters the blood flowing through the blood channel 41.
  • FIG. 6 is a conceptual diagram showing a hemodialysis apparatus having a blood channel layer, a dialysate channel layer, and a filtrate channel layer.
  • the blood flow path layer 43, the dialysate flow path layer 47, and the filtrate flow path layer 69 are preferably included in a plurality of layers. In this case, it is preferable that the blood flow path layer 43 and the dialysate flow path layer 47 and the blood flow path layer 43 and the filtrate flow path layer 69 are adjacent to each other.
  • the blood filtration membrane 61 has the same shape (here, hexagonal) as each layer.
  • FIG. 6 is a conceptual diagram showing a hemodialysis apparatus having a blood channel layer, a dialysate channel layer, and a filtrate channel layer.
  • the blood flow path layer 43, the dialysate flow path layer 47, and the filtrate flow path layer 69 are preferably included in a plurality of layers. In this case, it is preferable that the blood flow path layer 43 and the dialysate
  • the blood channel layer 43 is a layer provided in the first housing 3 and having the blood channel 41.
  • the blood flow path 41 is a blood flow path for guiding the blood flowing into the first housing 3 to the venous blood circuit 11.
  • the dialysate flow path layer 47 is a layer provided in the first housing 3 and having the dialysate flow path 45.
  • the blood whose waste product has been scraped by the blood filtration membrane 61 is discharged to the venous blood circuit 11. Further, the filtrate filtered by the blood filtration membrane 61 is discharged to a liquid discharge portion 63 (for example, a tube).
  • the liquid discharge part 63 is connected to a tube connected to the bladder, for example. Then, the filtrate accumulates in the bladder and is appropriately released outside the body.
  • the present invention can be used in the field of medical equipment.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

Le problème décrit par la présente invention est de fournir un dispositif d'hémodialyse qui réduit le risque d'accidents et d'infections et peut éliminer les déchets à un degré suffisant. A cet effet, l'invention concerne un dispositif d'hémodialyse qui comprend : une membrane de filtration d'hémodialyse 5 à l'intérieur d'un premier boîtier 3; un circuit sanguin côté artériel 7 pour faire circuler du sang dans le premier boîtier 3; un circuit sanguin côté intraveineux 11 pour faire sortir le sang du premier boîtier 3; une unité d'introduction de dialysat 21 qui est raccordée au premier boîtier 3 et introduit un dialysat dans le premier boîtier 3; une unité de décharge de dialysat 31 qui est raccordée au premier boîtier 3 et qui est destinée à décharger le dialysat qui a été à travers le boîtier; et une première unité de raccordement extracorporelle 25 pour raccorder une unité d'alimentation en dialysat d'un dispositif d'alimentation en dialysat extracorporel avec l'unité d'introduction de dialysat 21.
PCT/JP2019/002213 2018-02-09 2019-01-24 Dispositif d'hémodialyse implantable WO2019155895A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2019570668A JPWO2019155895A1 (ja) 2018-02-09 2019-01-24 インプラント血液透析装置

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018-022097 2018-02-09
JP2018022097 2018-02-09

Publications (1)

Publication Number Publication Date
WO2019155895A1 true WO2019155895A1 (fr) 2019-08-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2019/002213 WO2019155895A1 (fr) 2018-02-09 2019-01-24 Dispositif d'hémodialyse implantable

Country Status (2)

Country Link
JP (1) JPWO2019155895A1 (fr)
WO (1) WO2019155895A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112691248A (zh) * 2019-10-23 2021-04-23 希捷科技有限公司 人工肾脏
JP7202042B1 (ja) 2022-04-30 2023-01-11 慶應義塾 医療機器及びその製造方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5599258A (en) * 1979-01-25 1980-07-29 Nissho Kk Dialysis filtration type artificial kidney
JPS55133261A (en) * 1979-01-23 1980-10-16 Sodip Sa Device for disposing fluid regarded as object of medical technology
US20120289881A1 (en) * 2011-05-02 2012-11-15 Medtronic, Inc. System and Implantable Device for Treating Chronic Kidney Disease
JP2017158814A (ja) * 2016-03-09 2017-09-14 学校法人慶應義塾 血液濾過装置
WO2017192556A1 (fr) * 2016-05-05 2017-11-09 The Regents Of The University Of California Dispositif d'hémofiltration et ses procédés d'utilisation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55133261A (en) * 1979-01-23 1980-10-16 Sodip Sa Device for disposing fluid regarded as object of medical technology
JPS5599258A (en) * 1979-01-25 1980-07-29 Nissho Kk Dialysis filtration type artificial kidney
US20120289881A1 (en) * 2011-05-02 2012-11-15 Medtronic, Inc. System and Implantable Device for Treating Chronic Kidney Disease
JP2017158814A (ja) * 2016-03-09 2017-09-14 学校法人慶應義塾 血液濾過装置
WO2017192556A1 (fr) * 2016-05-05 2017-11-09 The Regents Of The University Of California Dispositif d'hémofiltration et ses procédés d'utilisation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112691248A (zh) * 2019-10-23 2021-04-23 希捷科技有限公司 人工肾脏
JP7202042B1 (ja) 2022-04-30 2023-01-11 慶應義塾 医療機器及びその製造方法
WO2023210761A1 (fr) * 2022-04-30 2023-11-02 慶應義塾 Instrument médical et son procédé de fabrication
JP2023164208A (ja) * 2022-04-30 2023-11-10 慶應義塾 医療機器及びその製造方法

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JPWO2019155895A1 (ja) 2021-03-25

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